Novartis AG

Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: • Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area • Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents • Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders • Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) • Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. • Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: ∙ Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise ∙ Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. ∙ ≥ 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. ∙ Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process ∙ Good knowledge of oncology and experience in early clinical development preferred. ∙ Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Global Program Clinical Head (GPCH) is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy. About the Role The role reports into the Clinical Development Head. Your responsibilities will include: • Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on NIBR clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-Development Decision Point, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. Minimum Requirements: MD or equivalent (required) PhD (preferred) 5 years professional experience as MD and a minimum of 10 years of experience with clinical drug development in an industry environment spanning clinical activities in Phases I through III/IV and experience with leading submission dossiers (required) Ideally a Board certified Nephrologist OR extensive (> 5 years) experience in clinical development withing the Nephrology Therapeutic area Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry This is a hybrid role based in Basel. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Senior* Clinical Development Medical Director (Sr* CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Senior/CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. This hybrid role can be based in Basel, Dublin, London, Barcelona or Madrid. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The *Senior/Clinical Development Director (*Sr. CDD) is the clinical/scientific expert and if assigned the clinical development lead of a section of a global clinical program and/or trial. (e.g., an indication, a new formulation, or a specific development phase) or a large, complex trial, under the leadership of the GPCH. The *Sr. CDD may be assigned to have a team leadership role for sections clinical programs and/or global clinical trials, depending on the size, nature and complexity About the Role Major accountabilities: Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program. Clinical deliverables may include the clinical development strategy for assigned program section(s), clinical sections of individual protocols consistent with the Integrated Development Plans (IDP), clinical data review program specific standards, clinical components of regulatory documents/registration dossiers, and publications Contributes and if assigned leads development and delivery of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drives execution of the section of the clinical program in partnership with global line functions, in particular clinical operations, trial leaders and data management/analysis, and regional/country clinical development associates Ensures ongoing clinical and scientific review of clinical trial data. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results. May be the Program or Function Manager of associates (e.g., CDD or associate CDD Supports GPCH in assessing overall risk-benefit of the molecule for the assigned section of the clinical program, may be a (core) member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety Member and if assigned may (co-)lead the Global Clinical Team (GCT), if there is a separate GCT for the assigned program section. Represents the section when assigned in Global Program Team (GPT) meetings, and as the section spokesperson in internal and external meetings/boards, as assigned Supports the Clinical Development Head (CDH) by providing clinical/scientific input into IDP/CDP and CTP reviews and contributing/driving development of disease clinical standards for new disease areas. May take on other TA responsibilities as directed by the CDH Minimum Requirements: Work Experience: Advanced degree in life sciences/healthcare (or clinically relevant degree) is required. PharmD, or PhD strongly preferred ≥ 10 years of involvement in clinical research, global drug development in an academic or industry environment spanning clinical activities in Phases I through IV. ≥ 5 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry. Experience in late phase clinical development strongly preferred Solid scientific writing skills Experience with regulatory submissions (IND, NDA/BLA, CTA/MAA) preferred Solid and advanced scientific acumen and ability to analyze and interpret scientific literature and data. Strong affinity with data, data quality and analysis. Preferred knowledge and/or experience of assigned therapeutic area Demonstrated ability to establish strong scientific partnership with key internal and external stakeholders ≥ 3 years people management experience required; this may include management in a matrix environment * Final job title Senior Clinical Development Director, Level 6 / Clinical Development Director, Level 6 and associated responsibilities will be commensurate with the successful candidates’ level of expertise. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050166 May 20, 2025 Switzerland Summary The Senior Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Sr CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 10 years of experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. - 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we-ll help you thrive personally and professionally:- Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Barcelona Gran Vía, Spain Alternative Location 2 Dublin (NOCC), Ireland Alternative Location 3 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Job Description Summary The Clinical Operations Program Head (COPH) is accountable to deliver data-driven, actionable operational and strategic insights for execution of a clinical development program and all associated trials by representing GCO at the Global Clinical Team (GCT) as well as at the Global Program Team (GPT). The COPH is accountable to plan the strategic operationalization of clinical drug development programs and trials in line with the needs of the EPTs/GPTs. This specific COPH role may be focused within Immunology, CRM or Neuroscience programs. The COPH leads the GCO sub-team to determine the GCO operational input to planning prior to any given development tollgate and to prepare the Operational Execution Plan (OEP), which is authored and owned by the COPH. The OEP incorporates both data-derived insights as well as country insights which enable informed decision-making, identify complexity, enable the generation of risk mitigation plans to reduce chances of delays, allow easier adaption of actions, and ensure transparency of the GCO operational position and the downstream delivery of program and trial milestones. To do this, the COPH owns the early viability assessments and program and trial feasibility of the planned programs and trials. During the execution of the trial (concept sheet onwards), the COPH will continue to lead the GCO sub-team to ensure the progress of the trial is in line with the OEP, to proactively deploy mitigation actions whenever necessary to ensure timely delivery of the trial as per plan. Experienced leader guiding members of the organization through the GCO organizational evolution, the evolution of new “product aligned” ways of working and of our overall culture. He / she champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. About the Role Major accountabilities: Lead operational delivery of the clinical development program and is responsible for the overall operational execution of the clinical program and related trials, as aligned with the IDP/CDP. Single GCO point of contact for assigned clinical development program and related trials. Key partner to GPCH during strategy, planning and execution stage of the program and related trials ensuring that the clinical science and strategy are consistently harmonized with an operationally feasible approach within the OEP-defined operational boundaries, so that the trials generate reliable information to answer the research questions and support decision making while protecting study participants. Leads operational delivery of the assigned program and related clinical trials and for all related strategic planning, prioritization of activities within that program and owns the early viability and feasibility assessment done by the GCO sub-teams as well as the development of operational scenarios for the execution of assigned programs and trials. Oversight and management of clinical trial budget for the assigned program and trials per OEP aligned with financial toll gates (e.g. IMB) and oversight of scope changes throughout the trial and program duration. Acts as a key partner to the GCO DU Head to use the operational insights developed with the GCO sub-team to actively shape the GDD DU strategy by driving the science of operations and GCO’s voice to ensure that the development strategy is operationally executable, thus contributing to both GCO and GDD DU mid to long term success. Is a key contact to senior leaders in GCO and beyond. Empowered to manage stakeholders, resolve conflict, and facilitate agreement. Actively monitor evolution and trends in Biopharmaceutical industry and may represent GCO and Novartis at Industry consortia. May be a member of Early Program Teams, providing an early and proactive assessment of operational viability of new clinical programs and ensuring that GCO’s assessment is correctly reflected in the overall program plans. In partnership with the GCO DU Head ensure that novel programs are reflected in the mid-long term GCO strategy and that GCO is prepared for their operationalization. The COPH champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. Essential Requirements : Bachelors in life science/healthcare required; Advanced degree or equivalent education/degree in life sciences/ healthcare preferred (PhD/MD/ PharmD/ Masters) and 10+ years relevant experience in pharmaceutical drug development. Experience in managing associates globally and in management in a matrix organization. Proven ability to lead cross functional matrix teams applying product-oriented agile ways of working. Strong leadership, interpersonal and problem-solving skills. High resilience and ability to advocate and implement new ways of working. Extensive knowledge of clinical development processes, preferably extensive knowledge of Novartis late-stage development processes or high likelihood to develop it within 6 months after appointment. Proven ability to lead in times of organizational transformation and to lead across organizational boundaries. Strong knowledge of therapeutic area or high likelihood to develop it within 6 months after appointment. Strong matrix management skills for bridging stakeholders (business, scientific, technical) Strong relationship-building skills; can influence, negotiate with and motivate executive leadership Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Discovery Postdoctoral Fellow in pathogenic, innate signaling in B cells About the Role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help uncover how the transcription factor IRF5 contributes to B cell-mediated pathology in systemic autoimmune diseases. You will be part of our Innate Immunity group in Basel, CH and work together with a cross functional team. The project aims to uncover the pathogenic role of IRF5 in autoimmune diseases by interrogating its role in transcriptional regulation of key pathways and target genes in B cells employing state of the art omics technologies (CUT&RUN, transcriptomics etc.) combined with in house mouse- and primary cellular models. Available patient samples will allow the candidate to translate findings to relevant diseases. The project will take advantage of readily available key reagents, assays, infrastructure, wet lab- and computational-workflows as well as access to a broad range of expertise covering immunology, various technologies and data science. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset. E.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Lead and drive multidisciplinary projects and engage with experts from diverse departments within Biomedical Research Develop and nurture relationships with key collaborators and stakeholders Present research findings and insights at internal and external meetings Actively participate and collaborate within the BR Postdoc community Role Requirements : PhD in immunology, molecular or cellular biology or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strong expertise in innate signaling or B cell biology, and molecular biology Strong publication records or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Candidates must be able to work independently as well as with interdisciplinary teams Experience in the following would be advantageous: experience with in vivo mouse work chromatin profiling and omics experiments computational skills (R, Phyton) to analyze own datasets How to apply Please submit your CV and cover letter by July 11th, 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054303 Jun 05, 2025 Switzerland Summary Discovery Postdoctoral Fellow in Cancer Functional Genomics About the Role About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our team in the Oncology Drug Discovery (ODD) group in Basel, Switzerland. You will work on a project that aims at understanding the molecular mechanisms regulating the activity of specific lineage-specific transcription factors, and how they selectively exert their oncogenic functions. You will employ cutting-edge gene editing and functional genomics techniques to dissect the structure-function relationship of these oncogenes, how they can differently regulate transcription and respond to external stimuli in the context of cancer, and help elucidate mechanisms of resistance that may arise upon pharmacological treatment. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams, maintain timely organized records, and actively participate in lab activities. Design, execute, analyze and evaluate experiments in various in vitro and ex vivo assays. Research scientific literature, implement new technologies, and present findings within the team and the broader community. Present at internal meetings, international conferences and publish in top-tier scientific journals. Role Requirements : PhD in molecular biology, cancer biology, biochemistry or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Knowledge in gene regulation, chromatin and transcription factor biology, particularly in the context of cancer. Strong experience with molecular biology tools, gene editing (e.g. knock-in/out, base editing) and genome-wide genomics techniques (e.g. ChIP-seq, ATAC-seq) Expertise in large-scale functional genomics screens (e.g. CRISPR screen, Perturb-seq, deep mutational scanning) Bioinformatics skills are beneficial. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV (with contact for three referees) and cover letter by July 1st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary Within Neuroscience our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. We are now looking for an International Value & Access Director to lead our global strategy for early pipeline programs. In this pivotal role, you will be responsible for developing and implementing strategies that ensure patients in the International region can benefit from our groundbreaking therapies. The Value & Access Director is dedicated to co-developing innovative and winning market access strategies, optimizing the payer value proposition and access-relevant evidence packages for assets, in partnership with the cross-functional teams. They develop and implement transformative access solutions serving strategic disease areas (DAs) and maximizing assets for International markets, with focus on our priority geographies (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) needs and feasibility. The main purpose of the Access Directors is to: Define Strategy • With International TA, develop and deliver all aspects of access strategy and execution for compounds/brands across the R-D-C continuum. • Enable asset strategy to translate science into payer and HCS value propositions and solutions, securing access, affordability, and contribute to wide scale patient access and efficiencies at scale. • Plays a critical leadership role in launch readiness, partnering across functions and key markets. Ensure Cross Functional Collaboration • Represent access with internal partners and external stakeholders. Internally, drive vision, inspire and provide leadership throughout the Access community (International, Regions, Countries) and with key partners (CPS/International, Development, Biomedical Research, Operations, S&G, Regions and Countries). Externally, represent Novartis in appropriate fora and organizations to drive the Novartis strategic access agenda. • Collaborate and partner with TAs, Medical Affairs, Development and Biomedical Research to enhance the value proposition, access strategy and access-relevant evidence packages. • With the commercial organization and Pricing team, (co-)create the international pricing strategy and guidance. • Create collaborative partnerships internally and externally to break down silos, partner across the value chain and shape the future of healthcare and markets. • Collaborate with S&G and Development to drive consistent and access-optimal approaches to product shaping, value propositions and HCS value creation. Act as a Thought leader within the Disease Area • Create and champion a compelling and competitive international strategic vision for how IM will innovate and expand access through DAs for the benefit of patients, Healthcare Systems, Payers, and Novartis • Active leadership in internal fora - enable broad country insights and alignment, and leverage external fora (e.g., EMA/EUnetHTA & advisory boards) to pressure-test strategies, level of evidence etc. for feasibility and success. • Stay abreast of internal and external developments, trends and other dynamics that affect the wider health policy and access domains, as well as of relevant scientific, clinical, and commercial developments. • Analyze and anticipate changes in priority international markets (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) to model future expenditures and project critical market access assumptions. About the Role Key Resposanbilities: Develop and maintain the Integrated Product Access strategy throughout the product lifecycle which clearly articulates the product strategy and differentiation most relevant to payers (e.g., well-defined target population, clinical endpoints, comparators, outcome measures, utility instruments, Health Economics data), patients, and HCS stakeholders worldwide. Develop payer negotiation strategy, upskill and prepare countries for their payer negotiations. Develop innovative patient access and contracting approaches, Managed Entry Agreements (MEAs) as required, to improve patient outcomes and support healthcare system affordability. Ensure that at launch, Novartis brands are supported by a robust payer value proposition particularly featuring core elements; ‘Value for money’ story, strong value evidence package and a pricing strategy maximizing the lifetime value of the brand (including existing and future evidence to justify price) and the reputation of Novartis. Ensure Access input is reflected in TPPs, clinical programs (including IEPs), BD&L assessments, asset maximization and indication sequencing Identify evidence, in addition to registration studies, required to meet the needs of medical experts and institutions involved in reimbursement & access decisions for key geographies. Collaborate with the HEOR & PCO team to ensure full integration of adequate HEOR/evidence deliverables in high quality cross-franchise strategy. Develop and rollout the “access toolbox” to share with priority markets (CN, DE, JP) major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) In collaboration with international or regional policy groups, develop and rollout materials which communicate the value of NVS medicines to HCS decision-makers, with focus on international forums and publications Manage Access community and budgets. Essential requirements: 5+ years of experience in market access roles 2+ years global or ex-US regional experience Experience working early in drug development lifecycle Product launch experience Cross functional and matrix influential experience across a team of multiple stakeholders Experience in driving commercial strategy driven through access or HEOR or pricing expertise Desirable requirements: 2+ years of experience in the relevant therapeutic area. Strong external network with thought leaders and influencers in the payer and HTA environment MBA, Ph.D., M.D. or RPh Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Within Neuroscience our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. We are now looking for an International Value & Access Director to lead our global strategy for the Spinal Muscular Atrophy (SMA) gene therapy pipeline. In this pivotal role, you will be responsible for developing and implementing strategies that ensure patients in the International region can benefit from our groundbreaking therapies. The Value & Access Director is dedicated to co-developing innovative and winning market access strategies, optimizing the payer value proposition and access-relevant evidence packages for assets, in partnership with the cross-functional teams. They develop and implement transformative access solutions serving strategic disease areas (DAs) and maximizing assets for International markets, with focus on our priority geographies (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) needs and feasibility. The main purpose of the Access Directors is to: Define Strategy • With International TA, develop and deliver all aspects of access strategy and execution for compounds/brands across the R-D-C continuum. • Enable asset strategy to translate science into payer and HCS value propositions and solutions, securing access, affordability, and contribute to wide scale patient access and efficiencies at scale. • Plays a critical leadership role in launch readiness, partnering across functions and key markets. Ensure Cross Functional Collaboration • Represent access with internal partners and external stakeholders. Internally, drive vision, inspire and provide leadership throughout the Access community (International, Regions, Countries) and with key partners (CPS/International, Development, Biomedical Research, Operations, S&G, Regions and Countries). Externally, represent Novartis in appropriate fora and organizations to drive the Novartis strategic access agenda. • Collaborate and partner with TAs, Medical Affairs, Development and Biomedical Research to enhance the value proposition, access strategy and access-relevant evidence packages. • With the commercial organization and Pricing team, (co-)create the international pricing strategy and guidance. • Create collaborative partnerships internally and externally to break down silos, partner across the value chain and shape the future of healthcare and markets. • Collaborate with S&G and Development to drive consistent and access-optimal approaches to product shaping, value propositions and HCS value creation. Act as a Thought leader within the Disease Area • Create and champion a compelling and competitive international strategic vision for how IM will innovate and expand access through DAs for the benefit of patients, Healthcare Systems, Payers, and Novartis • Active leadership in internal fora - enable broad country insights and alignment, and leverage external fora (e.g., EMA/EUnetHTA & advisory boards) to pressure-test strategies, level of evidence etc. for feasibility and success. • Stay abreast of internal and external developments, trends and other dynamics that affect the wider health policy and access domains, as well as of relevant scientific, clinical, and commercial developments. • Analyze and anticipate changes in priority international markets (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) to model future expenditures and project critical market access assumptions. About the Role Key Responsibilities: Develop and maintain the Integrated Product Access strategy throughout the product lifecycle which clearly articulates the product strategy and differentiation most relevant to payers (e.g., well-defined target population, clinical endpoints, comparators, outcome measures, utility instruments, Health Economics data), patients, and HCS stakeholders worldwide. Develop payer negotiation strategy, upskill and prepare countries for their payer negotiations. Develop innovative patient access and contracting approaches, Managed Entry Agreements (MEAs) as required, to improve patient outcomes and support healthcare system affordability. Ensure that at launch, Novartis brands are supported by a robust payer value proposition particularly featuring core elements; ‘Value for money’ story, strong value evidence package and a pricing strategy maximizing the lifetime value of the brand (including existing and future evidence to justify price) and the reputation of Novartis. Ensure Access input is reflected in TPPs, clinical programs (including IEPs), BD&L assessments, asset maximization and indication sequencing Identify evidence, in addition to registration studies, required to meet the needs of medical experts and institutions involved in reimbursement & access decisions for key geographies. Collaborate with the HEOR & PCO team to ensure full integration of adequate HEOR/evidence deliverables in high quality cross-franchise strategy. Develop and rollout the “access toolbox” to share with priority markets (CN, DE, JP) major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) In collaboration with international or regional policy groups, develop and rollout materials which communicate the value of NVS medicines to HCS decision-makers, with focus on international forums and publications Manage Access community and budgets. Essential requirements: 5+ years of experience in market access roles 2+ years global or ex-US regional experience Experience working early in drug development lifecycle Product launch experience Cross functional and matrix influential experience across a team of multiple stakeholders Experience in driving commercial strategy driven through access or HEOR or pricing expertise Desirable requirements: Therapeutic area expertise in SMA or with GTx. Strong external network with thought leaders and influencers in the payer and HTA environment MBA, Ph.D., M.D. or RPh Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are inviting applications for our Innovation Fellowship track of the Novartis Postdoctoral Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multi-disciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Transcription factors play pivotal roles in regulating immune responses, inflammation, and cellular stress pathways. However, their structural flexibility—often due to intrinsically disordered regions—has made them historically "undruggable." This project aims to overcome that challenge by leveraging novel mechanisms to selectively target these proteins. By modulating transcription factor stability, we aim to unlock new therapeutic strategies for immunological disorders with high unmet medical need, especially in patient populations unresponsive to current treatments. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Investigate novel mechanisms for targeted degradation of transcription factors, focusing on intrinsically disordered proteins (IDPs). Conduct cell-based and in vitro experiments. Analyze multi-omics data and apply AI-driven protein complex modeling in collaboration with data science experts. Work closely with cross-functional teams in immunology, chemistry, and structural biology as well as data scientists. Contribute to publications, and the development of new drug discovery technologies. Role requirements : PhD in transcription factor biology or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded June 2023 or later). Experience in understanding regulatory complexes using protein-based approaches as well as functional cellular assays. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills How to apply Please submit your CV and cover letter for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10057213 Jul 07, 2025 Switzerland Summary We are inviting applications for our Innovation Fellowship track of the Novartis Postdoctoral Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multi-disciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Transcription factors play pivotal roles in regulating immune responses, inflammation, and cellular stress pathways. However, their structural flexibility-often due to intrinsically disordered regions-has made them historically "undruggable." This project aims to overcome that challenge by leveraging novel mechanisms to selectively target these proteins. By modulating transcription factor stability, we aim to unlock new therapeutic strategies for immunological disorders with high unmet medical need, especially in patient populations unresponsive to current treatments. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Investigate novel mechanisms for targeted degradation of transcription factors, focusing on intrinsically disordered proteins (IDPs). Conduct cell-based and in vitro experiments. Analyze multi-omics data and apply AI-driven protein complex modeling in collaboration with data science experts. Work closely with cross-functional teams in immunology, chemistry, and structural biology as well as data scientists. Contribute to publications, and the development of new drug discovery technologies. Role requirements : PhD in transcription factor biology or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded June 2023 or later). Experience in understanding regulatory complexes using protein-based approaches as well as functional cellular assays. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills How to apply Please submit your CV and cover letter for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com, and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary We are thrilled to seek applications for our Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multidisciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Current human induced pluripotent stem cell (iPSC)- and embryonic stem cell (ES)-derived neurons are inherently immature, limiting their ability to model disease-relevant phenotypes, particularly in age-related disorders. Overcoming this challenge by enhancing maturation and introducing aging components is critical for creating more accurate and effective models of neurodegenerative diseases. Developing these advanced systems is essential, as the aging component is a key driver of these conditions and remains absent from current in-vitro models. The two goals of this innovation postdoc are: 1) How to drive these patient-derived induced neuronal cells to full maturity? 2) How to accelerate aging of these mature neurons to resemble neurodegenerative disease-like states? Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: • Work independently as well as with interdisciplinary teams. Design and execute experiments related to neuron aging, including data collection, analysis, and interpretation. • Through literature approaches, identify suitable protocols to develop an innovative new approach for iPSC maturation and driving aging. • Establish a fast cycle time to test and optimize new protocol ideas. • Establish benchmark experiments to validate maturity and aging of neuronal system. Role requirements: • PhD in molecular biology, neuroscience, tissue engineering, or a related field • Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). • Experience in neuronal cell culturing, iPSC, complex in-vitro systems, cellular aging. • Strong publication record or other scientific achievements (i.e. awards, patents, grants) • Excellent analytical, communication, presentation and organizational skills • Passion for fundamental exploratory research and boundless curiosity • A tinkering mindset How to apply Please submit your CV and cover letter by September 1st, 2025, for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10057139 Jul 07, 2025 Switzerland Summary We are thrilled to seek applications for our Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multidisciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Current human induced pluripotent stem cell (iPSC)- and embryonic stem cell (ES)-derived neurons are inherently immature, limiting their ability to model disease-relevant phenotypes, particularly in age-related disorders. Overcoming this challenge by enhancing maturation and introducing aging components is critical for creating more accurate and effective models of neurodegenerative diseases. Developing these advanced systems is essential, as the aging component is a key driver of these conditions and remains absent from current in-vitro models. The two goals of this innovation postdoc are: 1) How to drive these patient-derived induced neuronal cells to full maturity? 2) How to accelerate aging of these mature neurons to resemble neurodegenerative disease-like states? Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams. Design and execute experiments related to neuron aging, including data collection, analysis, and interpretation. Through literature approaches, identify suitable protocols to develop an innovative new approach for iPSC maturation and driving aging. Establish a fast cycle time to test and optimize new protocol ideas. Establish benchmark experiments to validate maturity and aging of neuronal system. Role requirements: PhD in molecular biology, neuroscience, tissue engineering, or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Experience in neuronal cell culturing, iPSC, complex in-vitro systems, cellular aging. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity A tinkering mindset How to apply Please submit your CV and cover letter by September 1st, 2025, for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com, and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people’s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities – all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and join us in reimagining new medicines together! The Role: As Global Program Regulatory Director, you will provide global leadership throughout the lifecycle of a development and/or marketed product program(s). Your experience will ensure that input from global HAs, regional and functional collaborators is collated to build a coherent, global regulatory strategy which fulfills the target product profile and portfolio objectives. You will also be responsible for identifying regulatory opportunities, mitigate against potential issues and ensure the execution of regulatory strategy across regions. In addition, you will lead global regulatory sub- team(s), share your regulatory and development expertise, and represent the RA function on cross functional initiatives and committees. About the Role Major accountabilities: Regulatory Strategy & Submissions With multiple stakeholders, develop, document and communicate high quality global regulatory strategies and HA interactions to achieve business objectives. Evaluate and communicate potential global regulatory opportunities and risks, developing mitigation strategies Leverage regional expertise in executing global regulatory strategy, and HA engagement. Provide strategic regulatory input into analysis and interpretation of scientific data, to key documentation, Leverage scientific knowledge and acumen in the analysis, interpretation and communication of data to colleagues. Lead interactions with Regulatory Affairs and Development Unit management and external consultants, for input to regulatory strategies. Accountable , in conjunction (with regulatory labelling) for maintaining Novartis core product information documents though product life cycle. Contribute to any BD&L Due Diligence activity Regulatory Excellence & Compliance Ensure compliance with global regulatory requirements and adherence to regulatory internal policies and processes, coordinating regulatory compliance activities at a global level. Provide support as needed for non-project related excellence activities. People As an effective matrix leader, provide feedback and mentor team members, line functions and sub- teams. Working with line managers, you will provide opportunities for team member growth and development, leading by example acting as a role model for Novartis values and behaviours. Your Experience: Science based bachelor's or master's degree. Advanced degree desirable. Significant regulatory and pharmaceutical development experience, across Phases I-IV. A track record of working with HA guidance and feedback, discussion and negotiations; post marketing/ brand optimization strategies and regulatory operations. Proven leadership success across a broad range of regulatory and pharmaceutical development activities. Strong interpersonal skills and experience working in a complex, cross functional organization, navigating complexity and leading cross function teams. Fluency in English. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050556 May 08, 2025 Switzerland Summary Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people-s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities - all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and join us in reimagining new medicines together! The Role: As Global Program Regulatory Director, you will provide global leadership throughout the lifecycle of a development and/or marketed product program(s). Your experience will ensure that input from global HAs, regional and functional collaborators is collated to build a coherent, global regulatory strategy which fulfills the target product profile and portfolio objectives. You will also be responsible for identifying regulatory opportunities, mitigate against potential issues and ensure the execution of regulatory strategy across regions. In addition, you will lead global regulatory sub- team(s), share your regulatory and development expertise, and represent the RA function on cross functional initiatives and committees. About the Role Major accountabilities: Regulatory Strategy & Submissions With multiple stakeholders, develop, document and communicate high quality global regulatory strategies and HA interactions to achieve business objectives. Evaluate and communicate potential global regulatory opportunities and risks, developing mitigation strategies Leverage regional expertise in executing global regulatory strategy, and HA engagement. Provide strategic regulatory input into analysis and interpretation of scientific data, to key documentation, Leverage scientific knowledge and acumen in the analysis, interpretation and communication of data to colleagues. Lead interactions with Regulatory Affairs and Development Unit management and external consultants, for input to regulatory strategies. Accountable, in conjunction (with regulatory labelling) for maintaining Novartis core product information documents though product life cycle. Contribute to any BD&L Due Diligence activity Regulatory Excellence & Compliance Ensure compliance with global regulatory requirements and adherence to regulatory internal policies and processes, coordinating regulatory compliance activities at a global level. Provide support as needed for non-project related excellence activities. People As an effective matrix leader, provide feedback and mentor team members, line functions and sub- teams. Working with line managers, you will provide opportunities for team member growth and development, leading by example acting as a role model for Novartis values and behaviours. Your Experience: Science based bachelor's or master's degree. Advanced degree desirable. Significant regulatory and pharmaceutical development experience, across Phases I-IV. A track record of working with HA guidance and feedback, discussion and negotiations; post marketing/ brand optimization strategies and regulatory operations. Proven leadership success across a broad range of regulatory and pharmaceutical development activities. Strong interpersonal skills and experience working in a complex, cross functional organization, navigating complexity and leading cross function teams. Fluency in English. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10040975 May 06, 2025 Switzerland Summary Location: Basel, Switzerland; Responsible for timely, independent management of complex intellectual property (IP) administrative, filing and legal support tasks. Proactive involvement in a high performing team providing a diverse range of complex IP administrative support for a defined group of patent practitioners in regional, international and foreign filing. Maintain and manage a complex, accurate docket, using a patent docketing system. Provides expert knowledge and understanding of IP law and practice issues. Undertakes operational and strategic responsibilities to maximize the effectiveness of paralegal sup-port at a local and global level. Responsible for applying, maintaining and contributing to the improvement of the department best practices. Responsible for training others in all areas of European Patents (EP) and foreign patent matters. Lead teams within the Patent Support team in areas of efficiency and improvement of current processes About the Role Your responsibilities include, but not limited to : Filing of EP/international and foreign patent applications and related correspondence from filing to issuance of grant. Responsible for EP and international patent filings, patent nationalizations into foreign jurisdictions, as well as foreign filings under other conventions. Responsible for preparing all documents required in connection with EP, Patent Cooperation Treaty (PCT) and foreign applications; proactively initiates preparation of responses to official communications and notifications. Maintain and share advanced knowledge of latest patent rules and adapting practices to comply. Monitor and updating electronic docket(s) for responsible attorney(s) and assigned paralegal tasks on a daily basis. Monitor all assigned cases and proactively ensuring that all related deadlines are met in a timely manner. Independent, proactive and critical review, maintenance and assistance of responsible attorney(s)- dockets and workload. Coordinate outsourcing, transfer in and transfer out of patent files and responsibilities in a timely and efficient manner, minimizing risk of loss of rights. Communicate effectively with colleagues, inventors, foreign agents and other associates. Actively participate in patent group and cross-divisional meetings as needed. Role includes on an as needed basis the flexibility to provide support in other areas within the Patent Support team (i.e. annuities, invoicing and data input). Undertake projects to address global prosecution and operational issues affecting department. Leads teams in development of procedures and processes. Ability to conduct meetings as needed. Recommends areas/systems of possible improvement in efficiencies in procedures. What you'll bring to the role: Relevant degree, Law - Paralegal/equivalent IP certification or equivalent experience Proficiency in English required - spoken & written, other languages is an asset. Demonstrated professional experience as a patent paralegal in a patent law firm or corporation with international and foreign filing experience. Ability to deal with a highly complex environment - manages workload and work product with high quality. Advanced knowledge and competency of patent database and report generating tools. Ability to work well and meet deadlines, without supervision, in an electronic office environment. Well-developed research and critical thinking skills, and sound decision-making abilities, with attention to detail to produce consistently accurate work Excellent analytical skills, organizational, and communication skills. Liaise with other cross-divisional groups to prevent duplication of effort and to ensure that effective knowledge sharing occurs. Demonstrates leadership qualities and ability to mentor and develop the technical competence of other paralegals. Ability to act as a champion for the Patent Support team at a NIBR site. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary As our Clinical Development Medical Director in our Immunology Development Unit you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. About the Role The Clinical Development Medical Director (CDMD) for Rheumatology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) Your responsibilities include, but are not limited to: • Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) • Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates • Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor • Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety • Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. • Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) • Work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters • Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support • Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. • May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: • MD (or equivalent medical degree) is required. • Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred • Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. • 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. • 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment • Showcase advanced knowledge of assigned therapeutic area • Demonstrate ability to establish strong scientific partnership with key partners • Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process • Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. • Exhibit excellent business communication and presentation skills • Possess strong interpersonal skills • Adept with excellent negotiation and conflict resolution skills Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons. This hybrid role can be based in Basel, London, Barcelona, Madrid or Dublin. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a Postdoc in bioprocess modelling and new technologies, you will be a key enabler for our aspirations to advance on the field of model-based development and optimization, as well as contribute to our innovation strategy. You will function as subject matter expert on in-silico modelling, data, and digital initiatives in close collaboration with experts within the Biologics community. About the Role Preferred start date : August 2025 Duration: 2 years Location: Campus Basel Your Responsibilities: Your responsibilities include, but are not limited to: Develop mathematical models (mechanistic, data-driven, hybrid) to characterize the production system (cellular, USP or DSP units, etc.) and its dynamic including uncertainty modeling. Design experiments in the context of model-based experimental learning to support the model development activities. Perform model verification and validation activities including historical and new data and convert model outcomes into practical relevant information for the purpose of process optimization/characterization. Identify and influence model-based and data driven initiatives. Contribute and function as a subject matter expert to the establishment of in-silico models in accordance with our data & digital strategy. Be proactively identifying challenges, proposing solutions, and communicating key issues to internal customers and partners. Align and collaborate with external vendors (if needed) to establish and implement innovative model-based solutions. What you will bring to the role: A PhD in relevant fields such as bio-chemical engineering, bioprocess technology, applied data science or similar with a strong background on process modelling (mechanistic, statistic and hybrid models) and optimization. Demonstrated programming skills (Python, R, and/or MATLAB), and knowledge of Machine Learning algorithms. Knowledge of USP/DSP (continuous/connected) processes, with the interest and ability to work on either field. Excellent ability to build collaborative relationships and a can-do mindset. Effective communication and presentation skills Proven ability to manage and prioritize multiple tasks. Agility to adjust to a fast-changing working environment. Proficiency in oral and written English Desirable requirements: Curious mindset with a strong interest in new technologies Attitude to resolve challenges with the ability to accurately balance between efforts, risks, and benefits. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: As a Formulation Project Leader in Oral Late Phase Development (NCE), you will lead and manage formulation and process development of Oral solid dosage forms from Lab-scale through scale-up and transfer to commercial scale in close collaboration with the Drug Product Subteam. Development activities include among others: formulation and process design and optimization, quality risk management as well as scientific writing of development documents and GMP documentation. For this position, special emphasis lies in bringing a keen interest and experience in applied data science and mechanistic modelling as tools to enable data-driven and efficient process development and scale-up. About the Role Your responsibilities will include but are not limited to: You have a passion for innovative formulations and technologies and bring experience in enabling formulation development. You understand the value and ideally bring experience of applying data-centric, computational models to guide formulation and manufacturing process development. You drive with scientific excellence the formulation development and manufacturing work of standard and enabling formulations and manufacturing processes of Oral Drug Products (NCE), supported by data-driven conclusions and mechanistic modelling. You collaborate closely with the Drug Product Sub-Team and Transfer Team members and together identify, understand and manage critical aspects concerning Drug Substance, Drug Product, Analytics, Packaging and Device. You maintain a regular exchange with key experts in e.g., Technology Focus Groups, Modelling & Simulation, Biopharmaceutics and further networks, and build their guidance into the development strategy and project plans. You author sound scientific and well-structured development documents as well as GMP documents to enable commercial manufacturing of new Drug Products. You contribute to the generation of CMC submission dossiers, support and answer Drug Product related questions of Health Authorities and Inspectors. What you’ll bring to the role: Advanced degree (minimum PhD) in relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 2 years of successful industry experience in the development of pharmaceutical formulations. Focus: Formulation and process development of standard and enabling formulations for small molecules (NCE) and scale up of manufacturing processes into oral drug products for commercialization. Knowledge of data science and data visualization, ideally experience of applying data-centric, computational models to guide formulation and manufacturing process development. Interdisciplinary thinking and interest in collaboration with other functions Broad and profound understanding of formulation development activities. Good knowledge of laboratory and/or technical tools (e.g., QbD, PAT) as well as knowledge of relevant GLP, GMP regulations and policies. Successfully demonstrated track record of creativity and problem solving in projects. Effective communication, organizational, planning and negotiation skills. Scientific and technical writing skills Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 About the Role Are you interested in pursuing a career in law? We have the perfect opportunity for you! Our legal trainee position offers excellent hands-on, in-house legal experience within the dynamic and multinational environment of a leading pharmaceutical company. More than 70’000 unique individuals work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world. We are seeking a motivated and diligent legal trainee who has the courage to navigate in unknown and ambiguous legal areas and has the curiosity to learn and being exposed to interesting and challenging new legal questions. If you're passionate about making a difference and keen to kickstart your career with our in-house team, this could be the ideal role for you. We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 Your responsibilities include: • You'll be the backbone of our Legal team, offering essential advice in employment law (including questions related to Diversity, Equity & Inclusion), as well as litigation and investigation. You'll have the opportunity to tackle complex global and local issues, transforming challenges into solutions. • You'll get your hands on practical tasks, managing individual legal cases, but also major projects (reorganizations, divestments, implementation of new policies and processes, etc.), drafting and reviewing agreements, internal regulations, and templates. This is your chance to shift from theory to practical application, making an immediate impact. • Your role will involve in-depth legal research and the creation of legal memoranda, helping us to break down complex ideas into digestible insights. Here, your knowledge will fuel our mutual success. • You'll also play a pivotal role in reporting key legal matters to our audit committees in strict adherence to the Sarbanes-Oxley Act. What you’ll bring to the role: • Swiss Bachelor of Law (BLaw) und Master of Law (MLaw) • Excellent proficiency in English and German, both in verbal and written communication • High motivation and ability to work independently on challenging tasks and projects • Prior legal internship and knowledge in employment law is a plus Are you ready to sharpen your skills and inspire change? If you're excited to contribute and learn, apply now, and submit a cover letter that includes your motivation for the position and your availability for six months starting in January or June 2026. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10048565 May 08, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: As a Formulation Project Leader in Oral Late Phase Development (NCE), you will lead and manage formulation and process development of Oral solid dosage forms from Lab-scale through scale-up and transfer to commercial scale in close collaboration with the Drug Product Subteam. Development activities include among others: formulation and process design and optimization, quality risk management as well as scientific writing of development documents and GMP documentation. For this position, special emphasis lies in bringing a keen interest and experience in applied data science and mechanistic modelling as tools to enable data-driven and efficient process development and scale-up. About the Role Your responsibilities will include but are not limited to: You have a passion for innovative formulations and technologies and bring experience in enabling formulation development. You understand the value and ideally bring experience of applying data-centric, computational models to guide formulation and manufacturing process development. You drive with scientific excellence the formulation development and manufacturing work of standard and enabling formulations and manufacturing processes of Oral Drug Products (NCE), supported by data-driven conclusions and mechanistic modelling. You collaborate closely with the Drug Product Sub-Team and Transfer Team members and together identify, understand and manage critical aspects concerning Drug Substance, Drug Product, Analytics, Packaging and Device. You maintain a regular exchange with key experts in e.g., Technology Focus Groups, Modelling & Simulation, Biopharmaceutics and further networks, and build their guidance into the development strategy and project plans. You author sound scientific and well-structured development documents as well as GMP documents to enable commercial manufacturing of new Drug Products. You contribute to the generation of CMC submission dossiers, support and answer Drug Product related questions of Health Authorities and Inspectors. What you-ll bring to the role: Advanced degree (minimum PhD) in relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 2 years of successful industry experience in the development of pharmaceutical formulations. Focus: Formulation and process development of standard and enabling formulations for small molecules (NCE) and scale up of manufacturing processes into oral drug products for commercialization. Knowledge of data science and data visualization, ideally experience of applying data-centric, computational models to guide formulation and manufacturing process development. Interdisciplinary thinking and interest in collaboration with other functions Broad and profound understanding of formulation development activities. Good knowledge of laboratory and/or technical tools (e.g., QbD, PAT) as well as knowledge of relevant GLP, GMP regulations and policies. Successfully demonstrated track record of creativity and problem solving in projects. Effective communication, organizational, planning and negotiation skills. Scientific and technical writing skills Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10050374 Apr 29, 2025 Switzerland Summary Job Description Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite 6000! That-s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. Global Discovery Chemistry is seeking a passionate, creative PhD level medicinal chemist to complement our nucleotide and siRNA chemistry team in Basel. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs. Please note that we have the option to hire someone at a Principal Scientist level if this role level is a better match to the experience and skill set of the applicant. About the Role Your responsibilities will include, but are not limited to: Work highly collaboratively in a multidisciplinary project team to discover and develop novel oligonucleotide therapies across various disease areas. Lead a team of scientists dedicated to design and synthesize new nucleotide building blocks, linkers, backbones from small to medium scale Intellectually contribute to and own the success of assigned projects. Together with project teams, contribute experimentally and intellectually to conceive, implement and explore innovative siRNA chemistries to address key scientific questions and ensure their smooth transition to development Lead siRNA drug discovery projects in partnership with leaders from other functions Review and critically analyse data from projects using state-of-the-art data analysis and digital tools, to identify complex problems, develop scientific hypotheses, and design molecules. Drive innovation for the establishment of new projects, including the development of exploratory projects portfolio, innovative drug discovery solutions, and evaluation of new technologies in the RNA therapeutics space. This also involves collaborating with internal and external partners around the world to progress our projects. Document and communicate results and scientific findings to internal and external audiences, in patent filings or scientific publications as appropriate Support and develop team members by sharing your know-how and hands-on experience across your work environment Provide mentoring to scientists and lead through coaching and development of scientists, independent of reporting line and/or group affiliation, to increase their impact on projects. What you will bring to the role: A PhD degree with a focus on synthesis and design of oligonucleotides. Demonstrated practical knowledge in medicinal chemistry with focus on oligo/nucleotides for 8+ years with a track record of deliverables. Experience in solid phase oligonucleotide synthesis is considered a plus A track record of people leadership and development skills A mind-set of curiosity and openness to diverse thinking, with an enthusiasm to develop yourself and others Innovative and independent problem-solving skills Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery Aptitude to work in a fast-paced team-oriented matrix environment Excellent written and verbal communication and strong influencing skills, with an ability to present and discuss project strategies and challenges Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Job Description Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite 6000! That’s the number of associates in the Novartis BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. Global Discovery Chemistry is seeking a passionate, creative PhD level medicinal chemist to complement our nucleotide and siRNA chemistry team in Basel. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs. Please note that we have the option to hire someone at a Principal Scientist level if this role level is a better match to the experience and skill set of the applicant. About the Role Your responsibilities will include, but are not limited to: Work highly collaboratively in a multidisciplinary project team to discover and develop novel oligonucleotide therapies across various disease areas. Lead a team of scientists dedicated to design and synthesize new nucleotide building blocks, linkers, backbones from small to medium scale Intellectually contribute to and own the success of assigned projects. Together with project teams, contribute experimentally and intellectually to conceive, implement and explore innovative siRNA chemistries to address key scientific questions and ensure their smooth transition to development Lead siRNA drug discovery projects in partnership with leaders from other functions Review and critically analyse data from projects using state-of-the-art data analysis and digital tools, to identify complex problems, develop scientific hypotheses, and design molecules. Drive innovation for the establishment of new projects, including the development of exploratory projects portfolio, innovative drug discovery solutions, and evaluation of new technologies in the RNA therapeutics space. This also involves collaborating with internal and external partners around the world to progress our projects. Document and communicate results and scientific findings to internal and external audiences, in patent filings or scientific publications as appropriate Support and develop team members by sharing your know-how and hands-on experience across your work environment Provide mentoring to scientists and lead through coaching and development of scientists, independent of reporting line and/or group affiliation, to increase their impact on projects. What you will bring to the role: A PhD degree with a focus on synthesis and design of oligonucleotides. Demonstrated practical knowledge in medicinal chemistry with focus on oligo/nucleotides for 8+ years with a track record of deliverables. Experience in solid phase oligonucleotide synthesis is considered a plus A track record of people leadership and development skills A mind-set of curiosity and openness to diverse thinking, with an enthusiasm to develop yourself and others Innovative and independent problem-solving skills Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery Aptitude to work in a fast-paced team-oriented matrix environment Excellent written and verbal communication and strong influencing skills, with an ability to present and discuss project strategies and challenges Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland; Responsible for timely, independent management of complex intellectual property (IP) administrative, filing and legal support tasks. Proactive involvement in a high performing team providing a diverse range of complex IP administrative support for a defined group of patent practitioners in regional, international and foreign filing. Maintain and manage a complex, accurate docket, using a patent docketing system. Provides expert knowledge and understanding of IP law and practice issues. Undertakes operational and strategic responsibilities to maximize the effectiveness of paralegal sup-port at a local and global level. Responsible for applying, maintaining and contributing to the improvement of the department best practices. Responsible for training others in all areas of European Patents (EP) and foreign patent matters. Lead teams within the Patent Support team in areas of efficiency and improvement of current processes About the Role Your responsibilities include, but not limited to : Filing of EP/international and foreign patent applications and related correspondence from filing to issuance of grant. Responsible for EP and international patent filings, patent nationalizations into foreign jurisdictions, as well as foreign filings under other conventions. Responsible for preparing all documents required in connection with EP, Patent Cooperation Treaty (PCT) and foreign applications; proactively initiates preparation of responses to official communications and notifications. Maintain and share advanced knowledge of latest patent rules and adapting practices to comply. Monitor and updating electronic docket(s) for responsible attorney(s) and assigned paralegal tasks on a daily basis. Monitor all assigned cases and proactively ensuring that all related deadlines are met in a timely manner. Independent, proactive and critical review, maintenance and assistance of responsible attorney(s)’ dockets and workload. Coordinate outsourcing, transfer in and transfer out of patent files and responsibilities in a timely and efficient manner, minimizing risk of loss of rights. Communicate effectively with colleagues, inventors, foreign agents and other associates. Actively participate in patent group and cross-divisional meetings as needed. Role includes on an as needed basis the flexibility to provide support in other areas within the Patent Support team (i.e. annuities, invoicing and data input). Undertake projects to address global prosecution and operational issues affecting department. Leads teams in development of procedures and processes. Ability to conduct meetings as needed. Recommends areas/systems of possible improvement in efficiencies in procedures. What you'll bring to the role: Relevant degree, Law - Paralegal/equivalent IP certification or equivalent experience Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as a patent paralegal in a patent law firm or corporation with international and foreign filing experience. Ability to deal with a highly complex environment - manages workload and work product with high quality. Advanced knowledge and competency of patent database and report generating tools. Ability to work well and meet deadlines, without supervision, in an electronic office environment. Well-developed research and critical thinking skills, and sound decision-making abilities, with attention to detail to produce consistently accurate work Excellent analytical skills, organizational, and communication skills. Liaise with other cross-divisional groups to prevent duplication of effort and to ensure that effective knowledge sharing occurs. Demonstrates leadership qualities and ability to mentor and develop the technical competence of other paralegals. Ability to act as a champion for the Patent Support team at a NIBR site. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050376 May 20, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Biologics Research Center (BRC) at Biomedical Research is seeking a highly skilled Structural Bioinformatician / computational chemist specializing in protein structure predictions, protein-protein/ ligand interactions, molecular dynamics simulations, and protein/ DNA /RNA structure analysis. The ideal candidate will join our Bioinformatics and Biotherapeutics Modelling team and contribute to our innovative biologics projects. About the Role Your responsibilities will include: Actively contribute to the biologics discovery pipeline and innovation-related programs by applying structure modeling methods to design novel molecules, optimize lead candidates, and design reagents at different stages of the drug discovery process. Assist scientists across the organization in the analysis and design of biologics sequences and structures, including xRNA therapeutic, advancing projects from early discovery to optimization stages. Apply, develop, and improve computational structural modelling methods to analyze data and design functional properties of drug candidates. Collect, analyze, and integrate diverse types of data, including structural data from different projects, to build predictive models, formulate hypotheses, and generate actionable knowledge. Contribute to the design, utilization, and improvement of bioinformatics tools in the field of molecular modelling to analyze sequence and structure data for knowledge generation. Work closely with experimental scientists, fostering a collaborative and multidisciplinary environment to drive project success. What you will bring to the role To be successful in this role, the ideal candidate should possess the following qualifications and skills: Educational Background: Recent Ph.D. (graduated within the last 3-6 months), MS (with 4+ years of relevant industry research experience) or equivalent degree degree in theoretical/ Computational chemistry, bioinformatics, structural biology, or a related field. Preferable experience includes structure-based drug design, QM/MM calculations, MD simulations (with enhanced sampling), molecular modeling, molecular design, and AI. Experience: Prior experience in the pharmaceutical or biotechnology industry is advantageous but not essential. Experience in a research or academic setting with a focus on biologics , including RNA or antibody based therapeutics, is also valuable. Technical Expertise: Proficiency in computational structural biology, molecular modeling, molecular dynamics simulations, and structural bioinformatics tools and software (MOE, Schrodinger, Rosetta, or similar) for structural analysis and structure-based biologics design. A comprehensive understanding of RNA structural biology and RNA-ligand interactions is preferred. AI/ML Proficiency: Experience in incorporating AI/ML models into in silico workflows, as well as monitoring performance, retraining, and updating models, is advantageous. Analytical Skills: Strong ability to analyze and interpret complex biological data, particularly in the context of protein sequences and structures. Programming Skills: Competence in programming languages such as Python, R, or similar, and experience with bioinformatics databases and tools. Familiarity with version control systems like Git for collaborative coding and project management is a plus. Innovation: A creative and innovative mindset, with a keen interest in advancing the field of biologics through cutting-edge computational methods. Problem-Solving: Demonstrated ability to develop hypotheses, design experiments, and drive projects to successful completion. Collaborative Spirit: Excellent communication and teamwork skills, with the ability to work effectively in a multidisciplinary environment. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Data and Digital Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. About the Role We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. This legal trainee position offers excellent opportunities to gain first-class, hands-on in-house legal experience within the stimulating, multinational environment of a leading pharmaceutical company. Duration: 6 months Start: January 1, 2025 Your responsibilities will include: • Support a diverse range of commercial matters relating to direct and indirect procurement, manufacturing, IT • Support diverse range of legal projects, e.g. contract templates, legal trainings, global legal research projects, digitalization, outsourcing, etc. • Assist with the drafting, negotiation and review of a variety of transactional, commercial and agreements • Draft legal memoranda on a wide variety of legal issues and disputes, Draft document and key position summaries • Provide legal advice to internal clients • You will be supervised and guided by a range of lawyers on different levels of the company, ensuring a great learning experience What you’ll bring to the role: Essential: • Swiss Law degree (Master of Law and Bachelor of Law has to be on Swiss Law), master's degree needs to be completed before start date • Business-level English skills (written and spoken), additional language is a plus • Interest in legal topics in a large multinational group of companies • High motivation to perform, to discover and learn new things and ability to work independently Desirable requirements: • Prior legal professional experience in a law firm, court or legal in-house department (internships etc.) would be helpful. We are also open to applicants without prior experience who have a strong interest and are motivated to learn on the job • Other professional experience in the corporate environment is a plus Please submit a cover letter that includes your motivation for the position and from when you will be available. Thank you. Why Novartis Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data Strategy and Management Platform, the Business Architecture & Data Integrations Capability Lead owns and oversees all aspects the Capability and contributes to the overall Platform strategy delivering business benefits, harmonization and continuous improvements. The Business Architecture & Data Integrations Capability lead is accountable for the overall cataloging of business data, defining data model requirements and Data Integration requirements. This role requires a deep understanding of regulatory data and how it flows through systems across the regulatory landscape, e.g. Data Lakes, Enterprise Data Warehouses, 3rd-party data integrations, regulatory technology solutions, etc. and how data flows in the registrations ecosystem across the Novartis Enterprise. About the Role Major accountabilities: Lead a team to ensure alignment with organizational goals and business priorities related to Business Architecture and Data Integrations Support the strategic vision for the Data Strategy and Management Platform, from a Capability level Define, prioritize, and deploy an integrated Capability roadmap working in close collaboration with relevant stakeholders and DDIT partners, ensuring alignment with the Data Strategy and Management Platform, Development and Enterprise data and technology strategy roadmaps Represent the Capability in digital governance boards and leadership meetings across the organization Represent the Capability in digital networks, externally (e.g. across Industries) as needed Oversee integrations with Products underlying the Capability Build and maintain collaborative and productive partnerships within the Capability and the Platform, and with relevant stakeholders to achieve business priorities. Oversees the cataloging and technical controls of the RA Data model in line with Novartis strategy and Industry Standards, business data architecture, Logical data model, Integration requirements, data model requirements and approves and secures data governance policies and processes Minimum Requirements: Bachelor’s degree, master’s; Advanced degree in life science, pharmaceutical, technology or data science preferred. 8+ years of relevant industry experience Strong understanding and direct relevant experience with the Business Architecture and Data Integrations landscape of pharmaceutical regulatory affairs and Regulatory Information Management Practical experience in technology process requirements and business administration management Deep knowledge of regulatory standards and structured data submissions Strong network and exposure to the external environment and ability to represent company and influence in Trade organizations (e.g., EFPIA, PhRMA), International Organizations (ISO), and collaboration with regulators (e.g. ICH, EMA SPOR), or consortiums Strong strategic problem-solving skills and ability to navigate un-charted territory without clear precedent Experience presenting/speaking at a senior management level with a proven track record of effectively communicating complex initiatives Demonstrated leadership in driving risk assessment and mitigation, clear strategic thinking, prioritization, maintaining awareness of business impact Excellent verbal and written communications Strong negotiation skills Broad experience in quality assurance/compliance, computer system validation within the pharmaceutical/biotech arena, the management and conduct of audits, stakeholder focus, and strong knowledge of regulatory requirements Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data Strategy and Management Platform team, the Data Governance and Quality Capability Lead is responsible for independently driving and implementing data standards and strategies for emerging data-driven HA requirements, and relevant systems’ governance processes across all domains and functions, in support of the NVS global product portfolios to improve data maturity according to RA business objectives. The Data Governance and Quality Capability Lead is accountable to drive harmonization and continuous improvement of Data Governance related activities and initiatives in close alignment with internal and external stakeholders to improve data maturity according to RA business objectives. The Capability Lead will drive the Centralized Data Quality Management culture in Regulatory Affairs and ensure Data Quality consistency, correctness and completeness across all applicable RA systems and platforms. About the Role Major accountabilities: Lead a team to ensure alignment with organizational goals and business priorities related to Data Governance and Quality Serve as Data Governance and Quality Capability Lead for RA and as the point of contact for GDD Data team Lead RA cross-functional teams to develop data roadmap, in alignment with cross-domain Data Governance boards Accountable to create and implement data management and quality strategy Expert contributor to influence draft guidance on data standards / specifications / implementation from Health Authorities and Trade Organizations. Prepare interpretative analyses about impact on internal data and digital processes. Collaborate with Development Data Management and DDIT partners to develop and implement RA Data Governance structures (boards) and policies, ensuring involvement of Business Process Owners (BPOs) and business SMEs. Oversee vendors at the Capability level, in collaboration with IT and the External Partnerships Teams Manage Data Governance and metrics reporting on data operating model throughout the DQM lifecycle Responsible for configuration, decision making and outcome, impacting the capability, with involvement of relevant Business Process Owner(s), business SMEs and stakeholders Minimum Requirements: Bachelor’s degree, master’s; Advanced degree in life science, pharmaceutical, technology or data science preferred 8+ years of relevant industry experience Strong understanding and direct relevant experience with the Data Strategy and Management landscape of pharmaceutical regulatory affairs and Regulatory Information Management Strong network and exposure to the external environment and ability to represent company and influence in Trade organizations (e.g., EFPIA, PhRMA), International Organizations (ISO), and collaboration with regulators (e.g. ICH, EMA SPOR), or consortiums Advanced knowledge of worldwide evolving external data standards as well as drug registration and approval processes and related document format requirements and in-depth knowledge of good Regulatory compliance and intelligence practices, policies, procedures Strong understanding of regulatory requirements and structured data submissions standards and initiatives Excellent business writing, communication and effective presentation skills. Extensive experience leading meetings, driving change and cross-functional teams Strong strategic problem-solving skills and ability to innovate, analyze and navigate un-charted territory without clear precedent, ability to troubleshoot effectively, accurately and independently. Strong negotiation skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Discovery Postdoctoral Fellow in Cancer Functional Genomics About the Role About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our team in the Oncology Drug Discovery (ODD) group in Basel, Switzerland. You will work on a project that aims at understanding the molecular mechanisms regulating the activity of specific lineage-specific transcription factors, and how they selectively exert their oncogenic functions. You will employ cutting-edge gene editing and functional genomics techniques to dissect the structure-function relationship of these oncogenes, how they can differently regulate transcription and respond to external stimuli in the context of cancer, and help elucidate mechanisms of resistance that may arise upon pharmacological treatment. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams, maintain timely organized records, and actively participate in lab activities. Design, execute, analyze and evaluate experiments in various in vitro and ex vivo assays. Research scientific literature, implement new technologies, and present findings within the team and the broader community. Present at internal meetings, international conferences and publish in top-tier scientific journals. Role Requirements : PhD in molecular biology, cancer biology, biochemistry or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Knowledge in gene regulation, chromatin and transcription factor biology, particularly in the context of cancer. Strong experience with molecular biology tools, gene editing (e.g. knock-in/out, base editing) and genome-wide genomics techniques (e.g. ChIP-seq, ATAC-seq) Expertise in large-scale functional genomics screens (e.g. CRISPR screen, Perturb-seq, deep mutational scanning) Bioinformatics skills are beneficial. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV (with contact for three referees) and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for Oncology and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for assets and develop policy and advocacy strategies for key in-market and launch assets in alignment with a broad range of cross-functional stakeholders. Oncology will be in particular focus beyond innovative platforms. Showing deep knowledge of the pharmaceutical business model, healthcare systems, and political and economic environment, this role will proactively shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting. Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identifykey policy priorities alignedwith strategy and priorities for the NVS portfolio Lead early portfolioscanningprocesswith Strategy & Growth for assigned TA and develop policy strategies andsolutionsfor key in-market and launch assets in alignment with International TA. Partner with cross-functional Teams (e.g.V&A,patientadvocacy,communications, medical,healthcaresystems) to supportdesignandimplementation ofpolicystrategy for assigned TA and to prepare favorable market conditions for priority pipeline assets. Align with regions (Europe, APMA, LaCan) anddirectreporting countries (US,CN,JP)on local policyprioritiesfor TA. Articulate priority policy asks for advocacy activities inregionsand keycountriesacross the portfolio and align with regional PA Portfolio Advocacy leadsto driveregionaland localexecution ofadvocacyactivities in the TA. Provide TA-specific thought leadership and insights for GPA-led engagements supportinghealthcare system & policy change. Develop policy resources, coordinateglobal events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. Based on a strong external network, build policy partnerships and coalitions as required. Provide policy thought leadership for Global Public Affairs led engagements that support healthcare system and policy change conducive to the Novartis portfolio. What you’ll bring to the role: ESSENTIAL CRITERIA: Extensive experience in therapeutic area-related life sciences policy, Public Affairs Policy and/or related fields, incl. policy focused patient advocacy. Established, public leadership position in Oncology related trade association working group and/or public fora, media. Experience representing the pharmaceutical industry in policy environment, with track record of measurable business impact with business and organizational awareness, enterprise perspective. Experience with designing and executing market shaping strategies across multiple geographies. Strategic sense and understanding of portfolio and commercial strategy development. Fluency in English. DESIRABLE CRITERIA: Master’s degree in relevant discipline / Advanced degree (PhD, MBA, or equivalent) in Pharmaceutical Sciences, Health Economics, Public Policy, or a related field. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary With over 60 years history in neuroscience, Novartis brought landmark therapies to patients with Multiple Sclerosis, Alzheimer’s disease, Parkinson’s Disease, Epilepsy, Depression and Migraine. We have a world-class pipeline in neuro-inflammation, neurodegeneration, psychiatric and neuromuscular diseases. Our holistic R&D approach includes cutting edge molecules, comprehensive approaches to technology, biomarker and digital therapeutics to propose better solutions for patients worldwide. About the Role As Global Program Clinical Head (GPCH), you are the clinical lead of Neuroscience, full development product. As a key member of the Global Program Team, you will contribute to the overall strategy in collaboration with relevant other functions such as Regulatory Affairs, Market Access and others. You will develop and ensuring the implementation of the Clinical Development plan and leading a cross functional team of specialists such as Medical Directors, Trial Directors, Safety Leaders, Biostatisticians and Regulatory Directors. The GPCH works to ensure early development plans and proof of concept studies are aligned with Development strategy and leads licensing evaluations for Clinical Development for the therapeutic area. In addition, you will lead the development and execution of the disease area strategy. What you’ll be doing: Responsible for clinical input to support Business Development & Licensing (BD&L) activities Serve as the Clinical Development Representative to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) Contribute to Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or more treatment indications and/or multiple programs. Drive creation and implementation of Clinical Development to support decision analysis and optimal resource allocation in program(s). Lead a cross functional team through the creation of clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency. As the medical expert, lead interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs, Marketing, Health Economics & Outcomes Research), and internal decision boards Together with Patient Safety, ensure continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Support registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Plan and implement publication and clinical communication strategy in coordination with Global Medical Affairs and Medical Writing, and provide input into key external presentations What you’ll bring to the role: MD, or PH. D degree with 10+ years’ experience in clinical research or drug development in an industry environment spanning clinical activities in Phases I-III/IV, including submission dossiers. A passion for Neuroscience Advanced expertise in Neuroscience with ability to innovate in clinical development study designs, provide relevant evidence to decision-makers and to interpret, discuss and present clinical trial or section program level data Detailed knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Desirable: MD or equivalent, MD or MD/PhD in Neurology, Experience in Cell&Gene, Rare or Neuromuscular diseases, Neuroinflammation of interest (preferred). This is a hybrid role and it can be based in Basel, London or Barcelona. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, colour, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051508 Jun 20, 2025 Switzerland Summary Novartis Biomedical Research (BR) serves as the innovation engine of Novartis, driving cutting-edge approaches to deliver therapeutic breakthroughs for patients. Within BR, the Discovery Sciences department pioneers early-stage drug discovery and promotes innovative therapeutics to tackle challenging disease targets. The Protein Sciences group in Discovery Sciences is an interdisciplinary team specializing in protein biochemistry, biophysics, NMR, X-ray crystallography, and electron microscopy. Our focus is to enable target-based hit identification, validation, and structure-guided drug discovery, with an emphasis on challenging targets such as membrane proteins. We are seeking a highly skilled and motivated Research Scientist / Senior Scientist with a strong background in protein expression and purification, ideally including experience with membrane proteins, to join our team in Basel, Switzerland. This is a unique opportunity to contribute to drug discovery across multiple disease areas within a dynamic, collaborative environment that values curiosity, innovation, and teamwork. About the Role Responsibilities You will work to produce high-quality proteins for drug discovery, focusing on small molecule hit generation, validation, and structural biology. Key responsibilities include: Express proteins insect and mammalian cell culture systems. Purify proteins using chromatography techniques and FPLC equipment to enable downstream assays and structural biology for drug discovery. Collaborate with team members to enable cryo-EM structural characterization of membrane proteins. Optimize protocols and processes through literature research, ideation and hands-on wet lab exploration. Work closely in a matrix setting with lab associates and present findings to project teams. Minimum Requirements Completed apprenticeship as a laboratory technician with 2 years of practical work experience or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field with strong experience in wet lab work. In-depth theoretical knowledge and hands-on experience in protein biochemistry, including expression, purification, and characterization. Strong collaboration, organizational, and communication skills in oral and written English, with the ability to effectively present results in team settings. Proactive interest in acquiring new techniques in protein biochemistry, biophysics, and structural biology. Desirable Requirements Hands-on experience in membrane protein expression, purification, characterization, and familiarity with cryo-EM workflows (sample preparation, grid handling). Prior exposure to an industrial research environment. Familiarity with software tools for structural analysis and AI driven protein construct design (PyMol, AlphaFold, etc.). Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Novartis Biomedical Research (BR) serves as the innovation engine of Novartis, driving cutting-edge approaches to deliver therapeutic breakthroughs for patients. Within BR, the Discovery Sciences department pioneers early-stage drug discovery and promotes innovative therapeutics to tackle challenging disease targets. The Protein Sciences group in Discovery Sciences is an interdisciplinary team specializing in protein biochemistry, biophysics, NMR, X-ray crystallography, and electron microscopy. Our focus is to enable target-based hit identification, validation, and structure-guided drug discovery, with an emphasis on challenging targets such as membrane proteins. We are seeking a highly skilled and motivated Research Scientist / Senior Scientist with a strong background in protein expression and purification, ideally including experience with membrane proteins, to join our team in Basel, Switzerland. This is a unique opportunity to contribute to drug discovery across multiple disease areas within a dynamic, collaborative environment that values curiosity, innovation, and teamwork. About the Role Responsibilities You will work to produce high-quality proteins for drug discovery, focusing on small molecule hit generation, validation, and structural biology. Key responsibilities include: Express proteins insect and mammalian cell culture systems. Purify proteins using chromatography techniques and FPLC equipment to enable downstream assays and structural biology for drug discovery. Collaborate with team members to enable cryo-EM structural characterization of membrane proteins. Optimize protocols and processes through literature research, ideation and hands-on wet lab exploration. Work closely in a matrix setting with lab associates and present findings to project teams. Minimum Requirements Completed apprenticeship as a laboratory technician with 2 years of practical work experience or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field with strong experience in wet lab work. In-depth theoretical knowledge and hands-on experience in protein biochemistry, including expression, purification, and characterization. Strong collaboration, organizational, and communication skills in oral and written English, with the ability to effectively present results in team settings. Proactive interest in acquiring new techniques in protein biochemistry, biophysics, and structural biology. Desirable Requirements Hands-on experience in membrane protein expression, purification, characterization, and familiarity with cryo-EM workflows (sample preparation, grid handling). Prior exposure to an industrial research environment. Familiarity with software tools for structural analysis and AI driven protein construct design (PyMol, AlphaFold, etc.). Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As part of the Drug Product Development Scientific Office you will provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g. modeling approaches) into CMC projects in collaboration with key stakeholders. You will also support CMC teams in compiling dossiers, drive engagement with industry consortia and health authorities to enable new technologies implementation. In addition, you will propose and lead elaborating scientific solutions to development challenges. About the Role Provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g., modeling approaches) into CMC projects in collaboration with key stakeholders. Promote a comprehensive approach to drug product development that focuses on the needs of patients and payers while integrating new technologies (pharmaceutical / in-silico) in line with Health Authorities expectations. Engage in industry consortia to shape regulatory environment and influence Health Authorities. Liaise with key stakeholders, including Biomedical Research, Global Program Teams, Devices and Primary Packaging, Regulatory CMC, Quality, and Commercial Manufacturing sites, to encourage them to integrate new technologies into our Biologics product while ensuring their needs for a patient-centric product are met. Support / drive interactions with health authorities through participation on briefing packages Proactively identify, lead/propose solution-oriented plans to resolve scientific drug product development challenges/barriers. Lead innovation programs as needed Minimum requirements 10+ years experience in the biopharmaceutical industry Experience in Biologics development, and specifically DP process development, understanding of drug product manufacturing process operations such as mixing, sterile filtration, and aseptic fill/finish. Experience in DP manufacturing of sterile dosage forms including frozen, liquid, and lyophilized formulations in vials and pre-filled syringes and other presentations Experience in writing regulatory modules including INDs and BLAs Relevant experience of developing and implementing strategies of patient-centered science related work Deep understanding of regulatory guidance from the FDA and EMA for development of biologic drug products, knowledge of USP and Ph. Eur. as it relates to biologics development Learning agility towards new delivery, DP process and other innovative technologies Experience of cross-functional collaboration and leading within a matrix organisation Outstanding influencing skills, leading without authority, excellent presentation and communication skills towards different internal and external stakeholders (senior management, health authorities), outstanding ability to deal with ambiguity, combined with demonstrating strong business acumen Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10056407 Jul 02, 2025 Switzerland Summary "We-re a team of dedicated and smart people united by a drive to achieve together" ***Closing date for applications 1700 BST 17th July 2025 Are you passionate about shaping the future of clinical development and making a meaningful impact in Cardiovascular medicine? We are looking for an experienced and visionary Clinical Development Medical Director (CDMD) to take the lead in driving the strategic planning and execution of our cutting-edge clinical programs with a focus on anticoagulation. In this pivotal role, you will oversee the end-to-end clinical development process for assigned programs within the Cardiovascular Therapeutic Area. Your expertise and leadership will ensure the seamless execution of clinical development plans while fostering a culture of empowerment, agility, and collaboration within a dynamic matrixed environment. If you thrive in a fast-paced, purpose-driven organization and have the skills to adapt swiftly to evolving business needs, we would love to have you on board! About the Role Major Accountabilities Providing or supporting clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution, the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Required Experience Essential MD or equivalent medical degree is required in addition to advanced knowledge and clinical training. Clinical practice experience (including residency/fellowship) and board certification or eligibility in Nephrology Experience in clinical research or drug development preferred Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. Experience in contributing to and accomplishing in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams- representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Barcelona Gran Vía, Spain Alternative Location 2 Dublin (NOCC), Ireland Alternative Location 3 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10056733 Jul 03, 2025 Switzerland Summary We are thrilled to seek applications for our Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multi-disciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years in length. There is a high interest in identifying disease-specific organ and tissue delivery methods for therapies like siRNA, gene, and radioligand, as well as various antibody formats across many diseases. Finding cell-specific targets or disease-specific tissues using transcriptomics or proteomics is challenging and often results in many potential targets needing individual validation. This postdoctoral research aims to use phenotypic phage display to identify antibodies and their corresponding targets in tissue ex-vivo or in-vivo, revealing novel binding mechanisms and epitopes not found in classical in vitro models. You will have the opportunity to work in a highly collaborative environment with diverse scientific and technological expertise through Biomedical Research. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Conceive, conduct, and analyze antibody phage display selections using complex biological systems like organs, tissue sections and/or organoids Characterize selected antibodies and identify their targets. Troubleshoot issues, analyze, and present data at internal meetings and boards as well as at external conferences Collaborate with cross-functional teams on target discovery and drug development projects Role requirements : PhD in Molecular Biology, Cell Biology, Biochemistry, antibody discovery or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strongly preferred: Hands-on experience in organoids handling, animal/human tissue sectioning and imaging, lysate preparation. Experience in setting up and maintaining isolated organ perfusion systems is a plus. Demonstrated proficiency in a broad range of techniques across molecular biology, protein biochemistry, cellular assays & analysis such as cloning, high throughput sequencing and data analysis, flow cytometry, confocal microscopy etc. Experience in phage display as well as previous experience in working in BSL2 environments are advantageous. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by August 3rd 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com, and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Job ID REQ-10027583 Jun 19, 2025 Switzerland Summary We-re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for Oncology and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for assets and develop policy and advocacy strategies for key in-market and launch assets in alignment with a broad range of cross-functional stakeholders. Oncology will be in particular focus beyond innovative platforms. Showing deep knowledge of the pharmaceutical business model, healthcare systems, and political and economic environment, this role will proactively shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting. Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identify-key policy priorities aligned-with strategy and priorities for the NVS portfolio- Lead early portfolio-scanning-process-with Strategy & Growth for assigned TA and develop policy strategies and-solutions-for key in-market and launch assets in alignment with International TA. Partner with cross-functional Teams- (e.g.-V&A,-patient-advocacy,-communications, medical,-healthcare-systems) to support-design-and-implementation of-policy-strategy for assigned TA and to prepare favorable market conditions for priority pipeline assets. Align with regions (Europe, APMA, LaCan) and-direct-reporting countries (US,-CN,-JP)-on local policy-priorities-for TA. Articulate priority policy asks for advocacy activities in-regions-and key-countries-across the portfolio and align with regional PA Portfolio Advocacy leads-to drive-regional-and local-execution of-advocacy-activities in the TA. Provide TA-specific thought leadership and insights for GPA-led engagements supporting-healthcare system & policy change. Develop policy resources, coordinate-global events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. Based on a strong external network, build policy partnerships and coalitions as required. Provide policy thought leadership for Global Public Affairs led engagements that support healthcare system and policy change conducive to the Novartis portfolio. What you-ll bring to the role: ESSENTIAL CRITERIA: Extensive experience in therapeutic area-related life sciences policy, Public Affairs Policy and/or related fields, incl. policy focused patient advocacy. Established, public leadership position in Oncology related trade association working group and/or public fora, media. Experience representing the pharmaceutical industry in policy environment, with track record of measurable business impact with business and organizational awareness, enterprise perspective. Experience with designing and executing market shaping strategies across multiple geographies. Strategic sense and understanding of portfolio and commercial strategy development. Fluency in English. DESIRABLE CRITERIA: Master-s degree in relevant discipline / Advanced degree (PhD, MBA, or equivalent) in Pharmaceutical Sciences, Health Economics, Public Policy, or a related field. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Corporate Affairs Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Communications & Public Affairs Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you a highly skilled and ambitious medical professional with a passion for research? If so, we have an exceptional opportunity for you! Novartis, a world-class pharmaceutical company, is seeking a Clinical Development Medical Director - Renal to join our team in Switzerland. As a Research role, this position offers a unique chance to contribute to groundbreaking medical advancements in the field of renal medicine. About the Role Novartis is seeking a highly qualified Clinical Development Medical Director - Renal **80-100% to join our exceptional team in Switzerland or the UK. As a world-class pharmaceutical company, Novartis is dedicated to improving global health through groundbreaking research and innovative solutions. Responsibilities: Lead the clinical development activities for renal disease therapeutic area, ensuring flawless execution of clinical trials. Collaborate with cross-functional teams to design and implement clinical development plans. Provide medical expertise and guidance throughout the clinical development process. Successfully compete clinical trial protocols, investigator brochures, and informed consent forms. Determine appropriate safety monitoring and risk management strategies. Ensure compliance with all applicable regulatory and ethical guidelines. Contribute to the preparation and submission of regulatory documents. Analyze and interpret clinical trial data to support decision-making. Participate in scientific conferences and present clinical trial results. Requirements: Medical degree and experience in Nephrology or a related field. Proven experience in clinical development within the pharmaceutical or biotech industry. Strong knowledge of renal diseases and related therapies. Excellent understanding of clinical trial design and execution. Exceptional communication and interpersonal skills. Ability to work effectively in a cross-functional and multicultural environment. Strong leadership and project management abilities. Proficiency in English, both written and spoken. Novartis offers a unique opportunity for a CDMD to contribute to innovative research and make a significant impact on patients' lives. Joining our team means working with individuals who demonstrate exceptional problem-solving skills and a dedication to collaborative work in a dynamic and driven environment. At Novartis we are committed to fostering diversity and inclusion. We are an equal opportunity employer (EOE) and value the contributions of individuals from all backgrounds. We strive to provide a work environment that promotes fairness, respect, and equal opportunities for growth and development. We also understand the importance of reasonable accommodations and adjustments for individuals with disabilities. If you require any accommodations or adjustments throughout the application process, please let us know, and we will ensure that your needs are met. Join a leading organization committed to revolutionizing healthcare through advanced research and inventive solutions. Apply today and contribute to our impactful work! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are looking for a currently enrolled Master student and can offer the rare opportunity to write a Master's thesis in our Data Science and Analytics Department. The task in a nutshell: Define the Data architecture of a solution elaborated in a project leveraging existing patterns. About the Role Data Architect - Internship We are looking for a Data Architect Intern to join our project team. The ideal candidate will have a strong understanding of data flow diagrams, data modelling, and data dictionaries. They will be responsible for designing consistent and efficient storage, integration, and access to data across the development process. Preferred Start Date : ASAP Duration : 6-12 months Key responsibilities: Design and maintain data flow diagrams, data models, and data dictionaries. Develop and implement data integration processes to combine data from multiple sources into a unified view. Establish relationships between data entities and set rules and standards for integration and interoperability. Ensure efficient data management and effective analysis/reporting to support business goals. Collaborate with various departments to ensure data architecture aligns with organizational objectives. Work Arrangement : Hybrid Minimum Requirements: Education : Currently enrolled in a Master's Degree in Computer Science, Information Technology, or a related field. Experience/Professional Requirements : Proven experience in data architecture, data modelling, and data integration processes. Desirable Requirements : Experience with data governance and metadata management. Familiarity with data storage solutions and data management tools Skills: Business Architecture. (Relito, Immuta) Enterprise Architecture. (Colibra) Data Quality (Ataccama) Data Governance. Solution Architecture. (databricks on AWS) Languages : Proficiency in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Novartis holds a rich development portfolio of small molecules ready to develop into innovative, patient centric, oral dosage forms. As a Drug Product Project Leader (DPPL) working on oral dosage forms, you will lead and manage formulation and manufacturing activities linked to pharmaceutical development for small molecules (New Chemical Entities; NCE). For this position, specific emphasis lies on bringing in-depth experience of pharmaceutical unit operations and related late-phase experience including scale-up and transfer to the commercial site. You will lead drug product teams during all stages of development with a specific focus on late clinical phases. You will be working on oral Small Molecules and in particular on enabling formulation approaches. You will use your strong communication, stakeholder management and influencing skills to effectively lead the drug product sub team and the transfer team in a matrix organization. Your expertise will facilitate the planning and execution of smart DoE and scale-up / transfer campaigns to establish robust manufacturing processes and stable drug products suitable for human trials and commercial supplies following ICH principles. About the Role Your responsibilities will include but are not limited to: You lead and manage all Drug Product (DP) related technical development activities for assigned projects and you represent DP project teams in Technical Research and Development (TRD) sub-teams based on your strong scientific and pharmaceutical development expertise. You lead, manage and support the DP and the transfer teams in line with Novartis values and behaviors. You build strong team spirit and promote knowledge exchange within and between teams. You motivate and coach team members for high performance. You formulate a sound DP project strategy incl. contingency planning and risk assessments as appropriate, involving functional experts, and you ensure alignment with Pharmaceutical Development department and other departments and functions inside and outside of TRD and 3rd parties as applicable. You ensure adherence to the scientific and project review process and through relevant scientific and project management governance boards You ensure creation of high quality and scientifically sound DP development documents enabling a strong CMC submission package, and act as author, reviewer or approver for development documents in accordance with operational procedures and guidelines. You contribute to the generation of registration dossiers, answer DP related questions in internal and external audits, and support Health Authority requests. What you’ll bring to the role: PhD in Pharmaceutical Sciences or relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 3 years of relevant technical experience in Development of oral Pharmaceutical Drug Products with proven experience in leading project teams in a matrix organization. Strong expertise in pharmaceutical oral dosage form development, manufacturing, and scale-up for formulations for Small Molecules including enabling formulations, manufacturing and IPC technologies, and scale-up principles. An understanding of material science principles, as applied to oral dosage forms, including the impact of physico-chemical properties of API and excipients on the drug product process and quality. Experience with application of Quality by Design and Quality risk management principles and tools as well as good working knowledge of regulatory guidelines relevant to Drug Product Development, validation, risk management, testing and stability, and new drug applications, together with technical writing and presentation skills. Ideally experience in applying data science, statistics, and DoE to enhance pharmaceutical development by providing a robust framework for data analysis, experimental design, and decision-making, leading to more effective and efficient drug development processes and documentation. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Access Directors are dedicated to co-develop innovative and winning market access strategies, optimizing the payer value proposition and access-relevant evidence packages for assets, in partnership with the CLS, IMA and V&A cross functional teams. They develop and implement transformative access solutions serving strategic disease areas (DAs) and maximizing assets, with focus on our priority geographic markets (CN, DE, JP), major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) needs and feasibility. About the Role Key responsabilities: Developing and operationalizing the Integrated Product Access strategy. Create and champion a compelling and competitive international strategic vision for how IM will innovate and expand access through DAs for the benefit of patients, Healthcare Systems, Payers, and Novartis Active leadership to enable broad country insights and alignment, and leverage external fora (e.g.,EMA/EUnetHTA & advisory boards) to pressure-test strategies, level of evidence etc. for feasibility and success With the TA, develop the international integrated product access strategy (IPAS) to deliver product differentiation most relevant to payers (e.g., well-defined target population, clinical endpoints, comparators, outcome measures, utility instruments, Health Economics data), patients, and HCS stakeholders worldwide. Ensure that at launch, Novartis brands are supported by a robust payer value proposition particularly featuring core elements; ‘Value for money’ story, strong value evidence package and a pricing strategy maximizing the lifetime value of the brand (including existing and future evidence to justify price) and the reputation of Novartis. Ensure access team develops and represents expert value evidence input into TPPs, clinical programs (including IEPs), BD&Ls, and develop any additional non-registration evidence to meet the needs of medical experts and institutions involved in reimbursement & access decisions for key geographies. Collaborate with the HEOR & PCO team to ensure full integration of adequate HEOR/evidence deliverables in high quality cross-franchise strategy. Ensure appropriate focus on priority markets needs into overall strategy. Ensure appropriate and timely access input into BD&Ls, asset maximization incl. indication sequencing. Maximize value of IM assets by creating and executing, together with TAs & pricing team, winning pricing strategies, global pricing guidance, incl. MEAs, PSPs, rigorous international pricing governance. Determine payer evidence requirements, risks/opportunities in the access landscape and create compelling access strategy with the TA and provide the “access toolbox” to share with priority markets (CN, DE, JP) major HTA archetypes (e.g., UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) Stay abreast of internal and external developments, trends and other dynamics that affect the wider health policy and access domains, as well as of relevant scientific, clinical, and commercial developments. Analyse and anticipate changes in priority international markets (CN, DE, JP), major HTA archetypes (e.g.,UK/CAN) and Budget Impact archetypes (e.g., Italy/Spain) to model future expenditures and project critical market access assumptions. Collaborate with S&G and Development to drive consistent and access-optimal approaches to product shaping, value propositions and HCS value creation. Disseminate value of medicines to HCS decision-makers with focus on international forums and publications in collaboration with international or regional policy groups. Manage Access community and budgets. Effectively work in matrix balancing cross-functional perspectives and alignment with business priorities against flexible resourcing. Essential requirements: 5+ years of experience in market access roles 2+ years global or ex-US regional experience Experience working early in drug development lifecycle. Product launch experience Cross functional and matrix influential experience across a team of multiple stakeholders Experience in driving commercial strategy driven through access or HEOR or pricing expertise Desirable requirements: MBA, Ph.D., M.D. or RPh. Experience in Rare & Renal Diseases 7+ years of experience in market access roles. 5+ years global or ex-US regional experience. Ex-US country experience. 2+ years of experience in the relevant therapeutic area​ Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Werden Sie Teil unseres Teams als Documentation Specialist GMP Sie haben ein Auge fürs Detail, arbeiten gerne strukturiert und möchten aktiv zur Qualitätssicherung in einem GMP-regulierten Umfeld beitragen? Dann sind Sie bei uns genau richtig! Als Documentation Specialist sind Sie verantwortlich für die Erstellung, Verwaltung und Übergabe von Chargendokumentationen, die Koordination von Dokumentenaktualisierungen sowie die Integration von CAPAs und Änderungen in die Produktionsunterlagen. Auch die Pflege des Dokumentenlebenszyklus und die Archivierung gehören zu Ihrem Aufgabenbereich. Werden Sie Teil eines hochmotivierten Teams von Expertinnen und Experten, das in einem dynamischen, funktionsübergreifenden Umfeld zusammenarbeitet. Wenn Sie eine ausgeprägte Qualitätsorientierung, Teamgeist und Erfahrung in regulierten Organisationen mitbringen, freuen wir uns auf Ihre Bewerbung! About the Role Ihr Verantwortungsbereich: Vorbereitung, Druck und Zusammenstellung der Chargendokumentation sowie Übergabe an die Produktionsmitarbeitenden innerhalb der im Produktionsplan festgelegten Fristen. Nachverfolgung und Koordination der Aktualisierung von Dokumenten in der Produktion (Verfahrensanweisungen und Logbücher). Verwaltung des Chargendokumentationssystems. Erstellung und Verwaltung von Revisionen der MBR bei papierbasierten Aufzeichnungen. Integration von CAPA (Corrective and Preventive Actions) und Maßnahmen im Zusammenhang mit Änderungsanträgen in die betreffende Chargendokumentation mit Unterstützung des zuständigen Process Experts. Erstellung neuer Dokumente (Master Batch Records, Formulare, Verfahrensanweisungen, Logbücher usw.). Verwaltung des Prüf- und Genehmigungszyklus von Dokumenten. Prüfung und Zusammenstellung der Chargendokumentation nach der Produktion zur fristgerechten Übergabe an die Qualitätssicherung in der geforderten Qualität. Durchführung von Eingaben und Überprüfung von Transaktionen/Erklärungen im ERP-System. Archivierung von Produktionsdokumenten. Was Sie zur Rolle mitbringen: Englischkenntnisse auf mittlerem Niveau und sehr gute Kenntnisse der lokalen Sprache am Standort. Nachgewiesene Erfahrung im Bereich Qualität und Compliance in einer Organisation (mindestens 5 Jahre). Grundlegendes technisches/Prozessverständnis, kaufmännische oder technische Ausbildung wünschenswert (Biologie, pharmazeutische Technologie, Biotechnologie oder vergleichbare Berufserfahrung). Hohes Maß an Gewissenhaftigkeit und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz). Teamplayer mit ausgeprägtem Teamgeist. Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortungsbewusstsein für die eigene Arbeit, Qualitätsverständnis. Selbstmotivation und Lernbereitschaft. Belastbarkeit. Diese Position ist auf 18 Monate begrenzt. Warum Novartis? Ueber 799 Millionen! - so viele Menschen haben wir mit unseren Produkten erreicht. Und obwohl wir darauf stolz sind, stellen wir uns kontinuierlich die Frage: Wie können wir in einer Welt des digitalen und technologischen Wandels noch mehr Menschenleben verbessern und verlängern? Wir sind überzeugt, dass wir Antworten finden können, wenn neugierige, couragierte und teamorientierte Menschen bestärkt werden, den Status Quo zu hinterfragen, mutige Entscheidungen zu treffen und innovative Wege zu gehen. Werden Sie Mitglied in unserem Novartis Netzwerk: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber in Verbindung bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, werden Sie hier Mitglied des Novartis Netzwerks: https://talentnetwork.novartis.com/network(link is external) *Hinweis: Einige Einschränkungen bei flexiblen Arbeitsmöglichkeiten könnten gelten und werden gegebenenfalls während des Vorstellungsgesprächs besprochen. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051302 Jun 03, 2025 Switzerland Summary Working primarily within our Diseases of Ageing and Regenerative Medicine (DARe) department at Biomedical Research, this Senior Principal Scientist role will lead in-vivo Imaging with the aim to deliver groundbreaking imaging techniques and technology to support and further Drug Discovery across our key research Disease Areas, including Oncology, Immunology, Neuroscience and Cardiovascular and Metabolic. About the Role The successful candidate will provide leadership of an in vivo imaging facility aiming to support the drug discovery process by assessing using imaging techniques (magnetic resonance imaging, ultrasound, computerized tomography, optical imaging) pharmacological interventions in relevant small rodent disease models and to identify/characterize imaging biomarkers. Key responsibilities will include but not be limited to: Leadership of an in vivo imaging facility and line management of laboratory associates with responsibility for coordinating activities and technical development Responsibility for maintaining equipment infrastructure as well as leading the development/improvement of techniques to address biological questions related to the projects. Maintenance of the infrastructure to support MRI, ultrasound, micro-CT and optical imaging equipment. Development, adaptation, and programming imaging and spectroscopy protocols to address questions of relevance to preclinical pharmacological studies. Interpretation, analysis and reporting of data obtained from applying these techniques and presentation of results in both written and oral format at team meetings and to management decision boards. Design, execution, analysis and reporting of state-of-the-art in-vivo mouse and rat experiments involving imaging/spectroscopy. Integration of in vivo imaging results into ex vivo tissue and biofluid analyses. Coordination with project team members across the organization and animal facilities in a matrix manner to ensure timely and successful execution of complex in vivo studies. Support the characterization of translational imaging biomarker candidates, in collaboration with the clinical imaging group at Novartis Minimum Requirements - what you will bring to the role: Scientific background in a relevant discipline (Physics, Chemistry, Engineering or Life Science) with a PhD and Postdoctoral research, with at least 2-3 years- experience in industry or with equivalent academic experience. Your academic and industry experience must include extensive in vivo experimentation and research applying imaging . Relevant experience in in-vivo imaging of small rodents documented through publications. Lab experience in in-vivo MR techniques with both the technical expertise as well as biological background to guide the application to in vivo experimentation. Prior Management experience managing an in vivo imaging laboratory within an academic or industrial environment with people leadership. Highly motivated to learn more about diseases of aging and regenerative medicine. Proactive and dynamic attitude with a demonstrable inquisitive mindset and a proven ability to formulate, articulate, and critically evaluate scientific experiments. Excellent teamwork skills and aptitude to work and thrive in cross disciplinary teams. High learning agility and a desire to be up to date with the latest animal work. Fluency in written and oral English with excellent presentation skills. Technical Skills: Experience with in vivo anatomical (MRI, CT, ultrasound) and molecular imaging techniques (e.g. PET, optical) and with in vivo spectroscopy (e.g. 31P MRS). Programming skills in the Bruker environment as well as in image analysis (e.g. Matlab). Data Analysis. Hypothesis Testing. Problem Solving. Accreditation for animal experimentation (LTK1/LTK2, FELASA B or equivalent). Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Accelerate operational excellence in Value and Access (V&A) by streamlining global operations and reporting, developing a robust delivery engine, and a worldclass Learning experience of associates globally across 100+ countries. Leadership of BSI V&A organisation to ensure execution for strategy into operational execution. Transform operational excellence into impactful market experiences through advanced technology and analytics solutions. About the Role Key Responsibilities: Operational Leadership: Lead a team of experts to drive efficient V&A delivery to International and markets. Lead integration of BSI V&A and ensure end to end delivery from strategy into operations. Enhance operational performance in V&A through strategic initiatives. Ensure seamless deployment of content, assets, and solutions across international markets. Roadmap Lead: Lead and oversee the execution of the newly implemented roadmap for the International V&A team, ensuring strategic alignment with global business objectives and access goals Foster cross-functional collaboration and communication with key stakeholders, Pricing, HEOR and Access teams, to drive cohesive strategies Technology and Analytics: Own and manage the V&A technology, data and analytics strategy and roadmap. Collaborate with DDIT and other technology/data teams to develop fit-for-purpose platforms and solutions. Facilitate the adoption of AI-powered business insights and analytics capabilities, training top countries to achieve tangible outcomes. Reporting: Define and introduce performance KPI reporting Regularly reports progress against standardized set of Performance KPIs Contribute to / lead International data collection, reporting strategic access initiatives for investor-relevant societal Indices such as ATMi, ESG, DSJI etc. to improve Novartis ranking Learning: Drive the identification of the most critical skills and knowledge needed for V&A associates to perform to the highest levels and with the wider International team design / deliver solutions that drive that impact Implement the Novartis Learning Strategy & the Novartis People Strategy in partnership with the P&O Team. Support Novartis to become the best company for learning and development by ensuring a culture of curiosity and continuous learning is embedded into the strategy and approach Team Management and Development: Recruit, develop, and retain a motivated, talented cross-functional team. Lead and foster a high-performance, diverse team culture using a lean team model with flexible staffing. Empower the team through unbossed leadership, enabling individuals to excel. Essential requirements: 15+ years Pharmaceutical industry experience (preferred in Market Access, Pricing or HEOR) Intrapreneur who thrives working in fast paced, complex and ambiguous environment while remaining flexible, proactive, resourceful, and efficient Advanced leadership experience from previous global or international leadership roles and from line managing direct reports in different locations Demonstrated sense of ownership and accountability for the shared success of the team Experience in developing and executing “Best in Class” processes at scale Experience in design, integration and implementation of skills and capabilities frame-works in a complex matrix environment Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Bringing life-changing medicines to millions of people, Novartis sits at the intersection of cutting-edge medical science and innovative digital technology. As a global company, the resources and opportunities for growth and development are plentiful including global and local cross functional careers, a diverse learning suite of thousands of programs & an in-house marketplace for rotations & project work. With strong medicines pipeline our current transformation will not just deliver growth for our business but continue to allow us to bring innovative medicines to patients quickly. The Global Clinical Imaging and Analytics Head will coordinate and lead the application of different imaging strategies to support our portfolio of innovative medicines spanning across oncology, cardiovascular, renal, immunology, and neuroscience. Will coordinate with cross-divisional multidisciplinary teams spanning clinical, data science and commercial functions to discover, develop, evaluate and implement innovative AI/ML derived imaging biomarkers/endpoint strategies across the Novartis portfolio. This role will collaborate extensively with internal and external stakeholders to access/leverage medical imaging data/platforms and build a Novartis high value portfolio and reputation in the fields of imaging technology and clinical radiology. About the Role Major accountabilities: Develop fit for purpose clinical imaging strategies/technologies for our clinical trials and ensure high quality training at clinical sites and to data acquisition Develop and lead unique Novartis strategies for mining internal and external medical image and device data to support innovative biomarker discovery, development and implementation in drug development across multiple therapeutic areas Leverage diverse knowledge and skillsets to fully integrate and effectively communicate with clinicians, epidemiologists, data scientists, imaging experts and software engineers to meaningfully advance translational research efforts, including integration into disease animal models and other “omics/phe-nomics” data sets, where appropriate, across multiple therapeutic areas Lead AI/Machine learning approaches to develop novel structural and functional biomarkers/endpoints from medical imaging and device data to enable better quantitation of common clinical parameters or improve diagnostics, sub-classify diseases and enable predictive patient risk/stratification Lead and partner to enable impact of data science derived imaging biomarker approaches in the early drug development portfolio for “Proof of Concept/Proof of Mechanism” with Translational Medicine across multiple therapeutic areas Partner and serve as a leadership team member with NVS data platform groups e.g. DATA42/Data Sciences and AI, to clarify the landscape of clinical needs, challenges and the scope of imaging/DICOM data available to enable new analytic approaches with existing radiology software suites as well as de novo deep learning models at the voxel level Collaborate with internal stakeholders to support the advancement of imaging data repositories and data collection technologies such that the data are of maximal value to NVS systems and processes. Shape NVS policies on imaging data storage, aggregation, harmonization, retention and application so that it is well positioned to benefit NVS now and in the future Lead collaborations with internal stakeholders across NVS e.g. Biomedical Research/Development - clinical, data sciences, Chief Digital Office/AI Innovation Center/DATA42 to fully leverage enterprise imaging and data science expertise, optimize our portfolio value and drive innovation Team management and responsibility for a group of 10-30 Associates Key performance indicators: Lead the discovery, advancement and qualification of specific imaging based biomarkers/endpoints which can deliver personalized medicine approaches across Novartis portfolio spanning over research and development programs, providing the highest value added medicines Enable BR and Dev to test biological and therapeutic hypotheses in clinical development, resulting in clear proof of concept/mechanism readouts, health authority endorsements, and commercial differentiation, potentially helping in successful program acceleration. Recognized internally and externally through publications, leading global strategies/teams and consortium impacts as a subject matter expert/leader for NVS Adherence to Novartis Values and Behaviors, especially innovation and collaboration Education/Experience : PhD/MD, preferably MD, board certified radiologist with clinical research and data sciences training and/or certification, as well as a deep understanding of clinical epidemiology that can be applied to questions of diagnosis, biomarker development and treatment monitoring 5 to 10 years professional/industry experience Extensive Clinical and Diagnostic Radiology experience in areas such as Cardiovascular, Immunology, Neurology, Renal and Oncology Experienced in medical multi-modality imaging platforms such as MRI, CT, PET and ultrasound Substantial impactful global experience developing and leading multidisciplinary matrix teams across Pharma/biotech (clinical research through healthcare applications), academic institutions, and commercial business functions Demonstrated technical and scientific expertise in multiple areas for development of innovative biomarker solutions Well-developed interpersonal skills with good presence and ability to influence and negotiate with senior leadership, experienced presenter and communicator Recognized internally and externally by key stakeholders; in depth understanding of external environment/trends; develops a strong professional network Languages: Fluent in oral and written English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards its-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are thrilled to seek applications for our Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role This applied research program is designed to change the way we approach drug discovery. As a fellow, you will learn to apply your skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in drug discovery as part of a multi-disciplinary team in Biomedical Research. Seize this chance to be at the forefront of the future of drug discovery! As part of the Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years in length. There is a high interest in identifying disease-specific organ and tissue delivery methods for therapies like siRNA, gene, and radioligand, as well as various antibody formats across many diseases. Finding cell-specific targets or disease-specific tissues using transcriptomics or proteomics is challenging and often results in many potential targets needing individual validation. This postdoctoral research aims to use phenotypic phage display to identify antibodies and their corresponding targets in tissue ex-vivo or in-vivo, revealing novel binding mechanisms and epitopes not found in classical in vitro models. You will have the opportunity to work in a highly collaborative environment with diverse scientific and technological expertise through Biomedical Research. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel Key responsibilities As an Innovation Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Conceive, conduct, and analyze antibody phage display selections using complex biological systems like organs, tissue sections and/or organoids Characterize selected antibodies and identify their targets. Troubleshoot issues, analyze, and present data at internal meetings and boards as well as at external conferences Collaborate with cross-functional teams on target discovery and drug development projects Role requirements : PhD in Molecular Biology, Cell Biology, Biochemistry, antibody discovery or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strongly preferred: Hands-on experience in organoids handling, animal/human tissue sectioning and imaging, lysate preparation. Experience in setting up and maintaining isolated organ perfusion systems is a plus. Demonstrated proficiency in a broad range of techniques across molecular biology, protein biochemistry, cellular assays & analysis such as cloning, high throughput sequencing and data analysis, flow cytometry, confocal microscopy etc. Experience in phage display as well as previous experience in working in BSL2 environments are advantageous. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by August 3rd 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Expert to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Expert with experience in Oligonucleotide analytics. About the Role Major accountabilities: You will help leading analytical activities within a Technical CMC project team (e.g., help to define control and specification setting strategies for Drug substances and Drug products, method development, validation, stability, and release testing) You provide valuable input to the analytical CMC documents and support regulatory submissions. Manage interactions and contribute to a high level of collaboration with internal and external stakeholders. Write of analytical source documents (e.g Analytical methods, Specifications, Validation reports, Stability reports) Lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. You will be responsible to evaluate and implement new analytical methodologies with the aim of bringing the lab at the forefront of Oligonucleotide analytics. You will be responsible for writing and reviewing analytical documentations with a high focus on quality, data integrity and timelines. You will drive, lead, and manage analytical activities including impurity profiling related to the analytical development of Oligonucleotides (e. g. method development, validation, stability, and release testing). Provide scientific guidance to the cross-functional and global project teams and thereby scientifically driving our exciting Oligonucleotide portfolio. Display a collaborative and inspired attitude within the Oligonucleotide lab, project teams and stakeholders is key. What you’ll bring to the role: Desirable: PhD in analytical chemistry or equivalent and a minimum 3 years’ experience in the pharmaceutical industry in analytical development, preferably in development of sterile parenteral products. Strong expertise in the field of oligonucleotide analytics. Profound knowledge in analytical separation techniques such as liquid chromatography (RP, IEX and HILIC) is a must. Experience in method development and troubleshooting. Experience in developing control strategies. Profound expertise in Mass Spectrometry (ranging from mass confirmation to actual quantitative analysis of impurities and sequencing) is a plus. Proven leadership in guiding and mentoring colleagues GMP experience and qualification expertise in a GMP environment are assets. Strong coordination skills, collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus Eager to develop new methods and assess new analytical techniques. High level of intrinsic motivation, excellent collaborative spirit and agility are key elements for our success. Analyse and interpret complex situations, provide detailed directions for analytical approaches Languages : English. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Your main responsibilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g. xRNAs) In your role, you will be leading an analytical subteam and preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaborate with internal and external stakeholders of drug development and coaching of analytical experts. You lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. Educational background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years’ experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus. Proven knowledge in Early or late phase parenteral development and filings Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. Collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus and experience in a cGMP environment. High level and intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is a key element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Good scientific/technical writing skills. Good understating on how to use novel digital tools to become more productive in a global project management environment. Proven leadership in guiding and coaching colleagues Excellent communication and role model skills Fluent in English (oral and writing), German/ French a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054201 Jun 05, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Your main responsibilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g.xRNAs) In your role, you will be leading an analytical subteamand preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaboratewith internal and external stakeholders of drug development and coaching of analytical experts. You leadoutsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. Educational background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years- experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus. Proven knowledge in Early or late phase parenteral development and filings Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. Collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus and experience in a cGMP environment. High leveland intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is akey element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Good scientific/technical writing skills. Good understating on how to use novel digital tools to become more productive in a global project management environment. Proven leadership in guiding and coaching colleagues Excellent communication and role model skills Fluent in English (oral and writing), German/ French a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Job Description Summary As a member of the Knowledge & Content Management Platform team, the Knowledge Management Capability Lead contributes to the strategic vision of Regulatory Affairs and supports the digitalization and centralization of Knowledge Management in RA, by overseeing one or several product(s) underlying the Capability. The Knowledge Management Capability is supporting knowledge gathering and sharing across the organization, as well as the leveraging of collaboration tools. This capability is defining the strategy for successful deployment and usage of knowledge management technologies, best practices, and advising on information structure. The capability is also supporting regulatory requirements gathering and availability, as well as advocating for an harmonized approach through the leveraging of state-of-the-art enterprise tools. The Capability should also ensure high user adoption & scale-up, and easy retrieval of information potentially leveraging Artificial Intelligence. The Knowledge Management Capability Lead is accountable to ensure that the Capability strategy delivers business benefits, and to drive harmonization and continuous improvements. About the Role Job Description Responsible to ensure alignment of a team with organizational goals and business priorities related to Knowledge Management Support the strategic vision for the Knowledge & Content Management Platform, from a Capability level Act as a Change Lead to drive system adoption, communication and training, at the capability level: implement change management strategies to ensure smooth adoption of technology initiatives Define, prioritize, and deploy an integrated capability roadmap working in close collaboration with relevant stakeholders and DDIT partners, ensuring alignment with the Knowledge & Content Management Platform, Development and Enterprise technology strategy roadmaps Represent the Capability in digital governance boards and leadership meetings across the organization and in digital networks, externally (e.g. across Industries) as needed Communicate effectively to ensure understanding and support for new technology initiatives Support continuous expansion of knowledge and foster the adoption of a digital mindset within the Regulatory Affairs team Oversee vendors at the capability level, across product(s), in collaboration with IT and the External Partnerships Teams Essential Requirements Must have Regulatory Affairs, Drug Development and Pharmaceutical experience. Oversee integrations with products underlying the Capability. Ensure on-time, compliant, secure, and quality delivery of portfolio for the assigned capability/product(s), aligned with the NVS Quality Manual Contribute to the change management strategy to ensure smooth adoption of technology initiatives, as required Ensure adherence to Security and Compliance policies and procedures within the scope of the Capability, and prepare for audit readiness and inspection requirements (incl. Related mitigations or actions triggered by audits & inspections). Responsible for Product(s) within the Capability. Can act as a product manager and a product owner Ensure on time, compliant, secure, and quality delivery of portfolio for the assigned product(s), partnering with relevant IT functions. Responsible to approve product-related requirements across product(s) underlying the Capability Responsible for configuration, decision making and outcome, impacting the capability, with involvement of relevant Business Process Owner(s), business SMEs and stakeholders Provide support/resources for key projects and programs with impact to the underlying product(s), ensuring timely delivery of high-quality milestones in alignment with business requirements. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? : https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Working primarily within our Diseases of Ageing and Regenerative Medicine (DARe) department at Biomedical Research, this Senior Principal Scientist role will lead in-vivo Imaging with the aim to deliver groundbreaking imaging techniques and technology to support and further Drug Discovery across our key research Disease Areas, including Oncology, Immunology, Neuroscience and Cardiovascular and Metabolic. About the Role The successful candidate will provide leadership of an in vivo imaging facility aiming to support the drug discovery process by assessing using imaging techniques (magnetic resonance imaging, ultrasound, computerized tomography, optical imaging) pharmacological interventions in relevant small rodent disease models and to identify/characterize imaging biomarkers. Key responsibilities will include but not be limited to: Leadership of an in vivo imaging facility and line management of laboratory associates with responsibility for coordinating activities and technical development Responsibility for maintaining equipment infrastructure as well as leading the development/improvement of techniques to address biological questions related to the projects. Maintenance of the infrastructure to support MRI, ultrasound, micro-CT and optical imaging equipment. Development, adaptation, and programming imaging and spectroscopy protocols to address questions of relevance to preclinical pharmacological studies. Interpretation, analysis and reporting of data obtained from applying these techniques and presentation of results in both written and oral format at team meetings and to management decision boards. Design, execution, analysis and reporting of state-of-the-art in-vivo mouse and rat experiments involving imaging/spectroscopy. Integration of in vivo imaging results into ex vivo tissue and biofluid analyses. Coordination with project team members across the organization and animal facilities in a matrix manner to ensure timely and successful execution of complex in vivo studies. Support the characterization of translational imaging biomarker candidates, in collaboration with the clinical imaging group at Novartis Minimum Requirements – what you will bring to the role: Scientific background in a relevant discipline (Physics, Chemistry, Engineering or Life Science) with a PhD and Postdoctoral research, with at least 2-3 years’ experience in industry or with equivalent academic experience. Your academic and industry experience must include extensive in vivo experimentation and research applying imaging . Relevant experience in in-vivo imaging of small rodents documented through publications. Lab experience in in-vivo MR techniques with both the technical expertise as well as biological background to guide the application to in vivo experimentation. Prior Management experience managing an in vivo imaging laboratory within an academic or industrial environment with people leadership. Highly motivated to learn more about diseases of aging and regenerative medicine. Proactive and dynamic attitude with a demonstrable inquisitive mindset and a proven ability to formulate, articulate, and critically evaluate scientific experiments. Excellent teamwork skills and aptitude to work and thrive in cross disciplinary teams. High learning agility and a desire to be up to date with the latest animal work. Fluency in written and oral English with excellent presentation skills. Technical Skills: Experience with in vivo anatomical (MRI, CT, ultrasound) and molecular imaging techniques (e.g. PET, optical) and with in vivo spectroscopy (e.g. 31P MRS). Programming skills in the Bruker environment as well as in image analysis (e.g. Matlab). Data Analysis. Hypothesis Testing. Problem Solving. Accreditation for animal experimentation (LTK1/LTK2, FELASA B or equivalent). Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary "We’re a team of dedicated and smart people united by a drive to achieve together" ***Closing date for applications 1700 BST 17th July 2025 Are you passionate about shaping the future of clinical development and making a meaningful impact in Cardiovascular medicine? We are looking for an experienced and visionary Clinical Development Medical Director (CDMD) to take the lead in driving the strategic planning and execution of our cutting-edge clinical programs with a focus on anticoagulation. In this pivotal role, you will oversee the end-to-end clinical development process for assigned programs within the Cardiovascular Therapeutic Area. Your expertise and leadership will ensure the seamless execution of clinical development plans while fostering a culture of empowerment, agility, and collaboration within a dynamic matrixed environment. If you thrive in a fast-paced, purpose-driven organization and have the skills to adapt swiftly to evolving business needs, we would love to have you on board! About the Role Major Accountabilities Providing or supporting clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution, the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Required Experience Essential MD or equivalent medical degree is required in addition to advanced knowledge and clinical training. Clinical practice experience (including residency/fellowship) and board certification or eligibility in Nephrology Experience in clinical research or drug development preferred Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. Experience in contributing to and accomplishing in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Biologics Research Center (BRC) at Biomedical Research is seeking a highly skilled Structural Bioinformatician / computational chemist specializing in protein structure predictions, protein-protein/ ligand interactions, molecular dynamics simulations, and protein/ DNA /RNA structure analysis. The ideal candidate will join our Bioinformatics and Biotherapeutics Modelling team and contribute to our innovative biologics projects. About the Role Your responsibilities will include: Actively contribute to the biologics discovery pipeline and innovation-related programs by applying structure modeling methods to design novel molecules, optimize lead candidates, and design reagents at different stages of the drug discovery process. Assist scientists across the organization in the analysis and design of biologics sequences and structures, including xRNA therapeutic, advancing projects from early discovery to optimization stages. Apply, develop, and improve computational structural modelling methods to analyze data and design functional properties of drug candidates. Collect, analyze, and integrate diverse types of data, including structural data from different projects, to build predictive models, formulate hypotheses, and generate actionable knowledge. Contribute to the design, utilization, and improvement of bioinformatics tools in the field of molecular modelling to analyze sequence and structure data for knowledge generation. Work closely with experimental scientists, fostering a collaborative and multidisciplinary environment to drive project success. What you will bring to the role To be successful in this role, the ideal candidate should possess the following qualifications and skills: Educational Background: Recent Ph.D. (graduated within the last 3-6 months), MS (with 4+ years of relevant industry research experience) or equivalent degree degree in theoretical/ Computational chemistry, bioinformatics, structural biology, or a related field. Preferable experience includes structure-based drug design, QM/MM calculations, MD simulations (with enhanced sampling), molecular modeling, molecular design, and AI. Experience: Prior experience in the pharmaceutical or biotechnology industry is advantageous but not essential. Experience in a research or academic setting with a focus on biologics , including RNA or antibody based therapeutics, is also valuable. Technical Expertise: Proficiency in computational structural biology, molecular modeling, molecular dynamics simulations, and structural bioinformatics tools and software (MOE, Schrodinger, Rosetta, or similar) for structural analysis and structure-based biologics design. A comprehensive understanding of RNA structural biology and RNA-ligand interactions is preferred. AI/ML Proficiency: Experience in incorporating AI/ML models into in silico workflows, as well as monitoring performance, retraining, and updating models, is advantageous. Analytical Skills: Strong ability to analyze and interpret complex biological data, particularly in the context of protein sequences and structures. Programming Skills: Competence in programming languages such as Python, R, or similar, and experience with bioinformatics databases and tools. Familiarity with version control systems like Git for collaborative coding and project management is a plus. Innovation: A creative and innovative mindset, with a keen interest in advancing the field of biologics through cutting-edge computational methods. Problem-Solving: Demonstrated ability to develop hypotheses, design experiments, and drive projects to successful completion. Collaborative Spirit: Excellent communication and teamwork skills, with the ability to work effectively in a multidisciplinary environment. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Onsite, full time, #LI-onsite About the role We are seeking a dedicated, innovative, and skilled neuroscientist to apply their research experience in neurodegenerative diseases to study age-related pathophysiological changes in the central nervous system (CNS) leading to progressive structural and functional decline. You will join our global, dynamic research environment to enable the discovery of new medicines addressing neurodegenerative diseases of aging. About the Role Our vision is to pioneer the development of novel therapeutic approaches from an understanding of age as the greatest risk factor for neurodegeneration and associated functional decline. The ideal candidate will have a strong background in neurodegenerative diseases, namely Alzheimer`s disease, and experience in the translational aspects of human pathophysiology with rodent model systems (in vivo/ex vivo) to enable deep insights into neuronal and other brain cell type pathobiology. As part of the Diseases of Aging and Regenerative medicine (DARe) disease area within Biomedical Research you will contribute to our global research efforts to elucidate and target the molecular mechanisms underlying neurodegenerative diseases to develop pharmacological interventions for patients. The role involves strong collaboration across the DARe In-vivo Physiology, In-vitro Biology and Data Science teams as well as collaborating with scientists from the Neuroscience disease area to drive our research goals. Major Accountabilities Your responsibilities include, but are not limited to: Managing a small in vivo laboratory team, designing and conducting state-of-the-art in-vivo mouse and rat experiments in support of research aiming to develop novel therapeutics for age-related neurodegenerative diseases with a particular focus on Alzheimer’s disease. Mentoring and career development of direct reports. Conducting cutting edge research on the pathophysiological changes in neurons and other CNS cell types, including synaptic dysfunction, and metabolic changes in aging and disease. Working at the interface between in-vitro biology, integrated pharmacology, aging and disease research and collaborating with a wide range of scientific experts globally across Novartis Biomedical Research to deliver new and actionable therapeutic targets for drug discovery to develop innovative medicines addressing neurodegeneration. Supporting the identification of biomarker candidates, elucidating the mode of action of drugs and understanding cross-talk between CNS cell types and across brain subregions as well as with other organs to delineate disease trajectories and novel drug intervention strategies. Integrating laboratory research of in vitro, in vivo and ex vivo tissue and biofluid analyses applying a broad range of molecular and cellular techniques. Interpreting and presenting results in both written and oral format at project team meetings and to management decision boards. What you’ll bring to the role: Essential: PhD with 3+ years post-doctoral research in neuroscience and hands-on experience in designing and conducting experiments with rodents, documented through publications. Accreditation for animal experimentation (LTK1/LTK2, FELASA B or equivalent). Deep knowledge of human and animal pathophysiology related to neurodegenerative diseases including Alzheimer`s disease. Additional expertise in neuro-endocrine systems, metabolism and CNS tissue homeostasis is advantageous. Fluency in the handling and analysis of large datasets and integration of genomic, proteomic and metabolomic data into research. Highly motivated to learn more about targeting neurodegenerative diseases of aging and regenerative medicine. Proactive and dynamic attitude with a demonstrable inquisitive mindset and a proven ability to formulate, articulate, and critically evaluate scientific experiments. Excellent teamwork mindset and high aptitude to work and thrive in cross-disciplinary teams. High learning agility and a desire to be up to date with the latest in vivo methodology. Fluency in written and oral English with excellent communication skills. Desirable requirements: Knowledge about aging biology. Experience in assessing pathophysiological cross-talk between different CNS cell types and CNS subregions as well as with peripheral organs. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Scientific Data & Products (SDP) group in Research Informatics (RX) is driven to maximize the impact and value to BR of software and data. We deliver powerful, functional, beautiful, and integrated software solutions that create a frictionless user experience. Our organization is here to build and apply excellence in product and data management to further Novartis drug discovery. About the Role As a Data Architect you will design an efficient, elegant, and high-performance data architecture and flow of data through the data systems backing our scientific data products. You will work closely with colleagues in product management, data engineering, business analysis and user experience, data science, and information security and risk management teams to deliver on our product vision. You will create an efficient, secure, compliant, performant, and sustainable data landscape which will be crucial for successfully achieving RX’s strategic goal of democratizing access to BR’s data. Major Responsibilities Independently design enterprise-quality data architecture sitting behind our products Frequently update the design to reflect learnings from our agile product teams Factor in BR- and Novartis-wide data ecosystem impact Define, initiate and/or drive solutions that enable smooth user experience of data flow and connectivity through entire processes across scientific domains with enterprise level impact Advance and achieve very high level of adoption of RX and industry best practices by product teams Design, implement and maintain security/infrastructure requirements for development / testing environment, OR design, implement and keep technology stack of relevant products for development, test and production use support OR manage application infrastructure including application infrastructure design input, application installation and deployment and operational management of the application infrastructure Work in close collaboration with Architecture and Operations to integrate new solutions, ensuring timely and cost-effective delivery of solutions required for new projects and high integration of components Help to drive architectural improvements and standardization for the infrastructure/security environments. Develop and enhance automated processes to release new solutions into the live environment or create reusable and automation frameworks Ensure controls are in place for all configuration items and only authorized changes are made for all assets within enterprise IT environment Ensure creation of detailed solution/service design matching high level designs and functional specifications to meet quality and performance requirements and ensure the quality, cost and timelines of feature and product implementations OR install applications per approved designs, acting as DevOps lead ensuring infrastructure is deployed/developed to meet technical design, and operationally manage application infrastructure, taking preventive measures to avoid unplanned outages Major accountabilities: A successful candidate must have extensive expertise in data architecture and experience with scientific data types used in drug discovery including biology, chemistry, and clinical data. Additional skills are required in the area of process change management and with the alignment of non-IT scientists behind strategic data management goals and initiatives. The ideal candidate demonstrates the following skills and capabilities: Expertise in data architecture, data engineering, or software engineering Excellent knowledge in at least two of BR’s core data areas (molecular biology, chemistry/chemical biology, clinical) Experience with developing or supporting standard IT products used in these core data areas together with an excellent understanding of the data flows between those Proven experience with architecting IT solutions that enable laboratory data workflows on a global company level Balancing corporate and departmental priorities and goals on a global level Proven mindset that demonstrates an understanding of the needs of a global company’s digital journey Proven drive for ensuring data consistency Consensus-building skills and ability to win others in IT and science to follow a shared vision Proven ability to execute consistently, rapidly, and effectively Outstanding communication skills and excellent stakeholder management Proven ability to operate successfully at the challenging interface between research and development functions and aligning their diverse needs Expertise in identifying and/or creating initiatives that move the organization to new levels of effectiveness Ability to improve processes and methods across scientific domains and laboratory workflows Experience with agile software development Experience with linked data concepts, technologies, and tools Essential Requirements: Master’s degree (or equivalent experience) Excellent technical skills with at least 10 years experience as a data architect, data engineer, or software engineer 5+ years experience creating scientific software, or working in a drug discovery environment or related scientific field Proven experience in managing scientific domain-specific data and metadata Experience in the practice of agile software development processes Experience with distributed data processing and management systems Experience in working with ontologies and managing data described in RDF Experience with cloud technologies (AWS, Google, or Azure) Proficiency in English (Oral & Written) Desirable: Experience working with Graph databases is a plus ou’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) for Immunology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050821 May 27, 2025 Switzerland Summary The Clinical Development Medical Director (CDMD) for Immunology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years- experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture&nbsp ; You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director – Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis is at the forefront of medical research and bringing innovative and life changing medicines to millions of patients. Animal research is key to many of the great medical advances of today and animals play an integral part in the discovery and development of innovative, safe and life-saving medicines for patients. The Basel Head of Animal Welfare and Integrity Assurance (AW&IA) will lead, manage, and evolve the internal animal care and use program oversight for Biomedical Research Basel. About the Role Novartis upholds the highest standards and ethics of Animal Welfare and research, with steadfast commitment to the 3Rs principles (Reduction, refinement, Replacement), as well as introducing further improvements including the ‘4th R’ of Responsibility and our Biomedical Research sites all earning independent, international Gold Standard accreditation from the Association for Assessment and Accreditation of Laboratory Care (AAALAC). The Head of Animal Welfare and Integrity Assurance will ensure that all work involving research animals at Biomedical Research Basel is in compliance with Swiss laws and the Novartis Animal Welfare policies and standards. The role will include responsibilities such as liaising on behalf of Novartis Biomedical Research with regulatory authorities, accreditation bodies, and external groups and championing animal welfare and the 3Rs, as well as advocate for the critical role of animals in biomedical research. Your Responsibilities will include but not be restricted to: Lead internal oversight of the Biomedical Research Basel animal care and use program, including acting as site’s Lead Animal Welfare Officer and key contact for all in vivo users, regulators, and accreditation bodies. Direct Biomedical Research Basel AW&IA activities as Site Head to achieve efficient, consistent, compliant, and continuous improvement of animal care and use oversight operations, including: management and support of the license review and animal number reporting process post-approval monitoring program semi-annual inspections and program reviews investigation of reported animal welfare concerns/non-compliances ensure appropriate management of the Animal Welfare Body meetings as chair and all related preparation, facilitation, administration and follow-up actions serve as key contact to in vivo leadership including to the Institutional Official, Basel Pharmacology Council, and Basel Leadership Team support the development of the new animal management system Serve as named main point of contact for regulatory and accreditation needs, including both announced and unannounced inspections, communication with the Cantonal and Federal veterinary authorities, for documentation/information (e.g. lead AAALAC program description and site visits), and reporting out to agencies on applicable timelines (e.g. annual reports, ad hoc event reporting) Lead and manage direct reports in local AW&IA team, ensuring their development and appropriate time management. Act as a key contributor to the Global AW&IA team representing the Basel site to the Ethical Review Council, Global 3Rs Working Group and Global Risk Review teams Promote the 3Rs via leadership or delegated leadership of the local 3Rs Working Group including promotion of the 3Rs Awards programs and Innovation in 3Rs Granting program Together with colleagues in Public Affairs, promote openness and education about the continued need for and value of animal research through internal and external collaborations and communication, including participation in direct political stakeholder engagement. Minimum Requirements – what you will bring to the role: Education : University degree (PhD, Vet med, Med) in biology, veterinary medicine or medicine. Special knowledge in laboratory animal science and alternative methods. Authority approved study director role in Switzerland Experience in regulatory compliance and working as an Animal Welfare Officer in Switzerland, leading an IACUC or animal welfare body Experience: At least 5 years experiences in animal experimentation and leading and managing personnel in an in-vivo research environment Experienced in leading and managing a team of Direct and indirect Reports in a complex matrixed research and operations pharma industry environment Knowledge in public relations and Professional experience in communicating about and supporting advocacy efforts for the need for animal research to internal and external audiences highly desirable Experience working collaboratively with regulators and accreditation bodies Experience in supporting 3Rs (reduce, refine, replace animal studies) programs Languages: English and German fluent, proficiency in e.g. French would be of advantage. Desirable Continuous improvement skills and experience in using evidence to design and test improvements to programs and processes, including advancing AI and automation in licensing and reporting Experience in assessing animal care and use programmes requiring larger laboratory animal species, including Non-Human Primates (NHP), Pig, and Dog Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Without safe, easy-to-use, high-quality drug delivery systems our patients could not get their medicines. This is where you come in; the Device Technology Solution Center needs you as Senior Expert Engineering for the development of drug device combination products working alongside our talented, bright and diverse teams. Our Device Technology Solution Center drives the technical development of auto-injectors as well as novel drug delivery principles, e.g. drug delivery to the brain or radioligand therapy. We closely collaborate with project management, human factors engineers, packaging experts, analytical testing, production, external partners, regulatory experts and many more. The aim is to develop and/or integrate innovative drug delivery systems with drug formulation and author state-of-the-art technical documentation for health authorities and production. About the Role Your Responsibilities: Your responsibilities include, but are not limited to: Develop platforms and collaborate with cross-functional teams to deliver safe, user-friendly, and reliable products Lead and support teams in the field of assembly and injection molding for device/part design, equipment and process across from prototyping to commercial scale Create and maintain relevant Design History File (DHF) documents, ensuring high-quality device design and development Contribute to all phases of medical device development: ideation, prototyping, piloting, and manufacturing transfer Ensure components meet quality standards for clinical trials and commercial production Collaborate with external partners, including prototypers, toolmakers, and CMOs Identify root causes of issues, define and implement robust solutions Role Requirements Degree in mechanical engineering or equivalent Preferably 10 years of experience in medical device development Proficient spoken communication and excellent technical writing skills in English Proven experience in production of plastic and metal components Proven experience in assembly of plastic and metal components / sub-assemblies Proven experience in design for manufacturing and design for assembly Good knowledge in key regulations and standards (e.g. ISO 13485, ISO 23908, ISO 11608, ISO 10993, MDR, Design Controls) Ability to interact with cross functional team in matrix organization Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10055763 Jun 26, 2025 Switzerland Summary We are seeking a motivated analytical expert for biopharmaceutical production within the framework QC testing for in-process controls, raw materials and drug substance. The role involves leading current and future analytical control strategies, focusing on release testing, method validation, and method transfer for new biopharmaceutical entities. About the Role Major accountabilities: Coordinate, review and release of quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Participate in or create, review, approve registration documents Manage analytical weak points of assigned pipeline Perform deviations/OOX investigation Support troubleshooting for testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis, Bioburden and Endotoxin Lead validation and transfer activities for analytical procedures Lead qualification, maintenance, and calibration of instruments Lead LabOpex Projects Key performance indicators: Timely completion of key deliverables Prompt reporting of missed deadlines and aim for shortest possible lead times Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities continuous readiness for inspection Proactively identify and implement cost-reducing optimizations Minimum Requirements: MSc or PhD in biotechnology, analytical chemistry or related field, +3 years industry experience Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage Reliability, flexibility, resilience, and strong teamwork skills Skills: Continuous learning Dealing with ambiguity Decision making GMP Industry standards Laboratory equipment Laboratory excellence Quality Control (QC) testing Quality Control sampling Self awareness Technological expertise Languages : Fluent in English and German (spoken and written) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We are seeking a motivated analytical expert for biopharmaceutical production within the framework QC testing for in-process controls, raw materials and drug substance. The role involves leading current and future analytical control strategies, focusing on release testing, method validation, and method transfer for new biopharmaceutical entities. About the Role Major accountabilities: Coordinate, review and release of quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Participate in or create, review, approve registration documents Manage analytical weak points of assigned pipeline Perform deviations/OOX investigation Support troubleshooting for testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis, Bioburden and Endotoxin Lead validation and transfer activities for analytical procedures Lead qualification, maintenance, and calibration of instruments Lead LabOpex Projects Key performance indicators: Timely completion of key deliverables Prompt reporting of missed deadlines and aim for shortest possible lead times Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities continuous readiness for inspection Proactively identify and implement cost-reducing optimizations Minimum Requirements: MSc or PhD in biotechnology, analytical chemistry or related field, +3 years industry experience Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage Reliability, flexibility, resilience, and strong teamwork skills Skills: Continuous learning Dealing with ambiguity Decision making GMP Industry standards Laboratory equipment Laboratory excellence Quality Control (QC) testing Quality Control sampling Self awareness Technological expertise Languages : Fluent in English and German (spoken and written) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our Neuroinflammation team within the Neuroscience Research Department in Basel, Switzerland. About the Role We are seeking an independent, highly motivated and dedicated researcher with substantial background and knowledge in neuroinflammation, microglia biology and advanced technical expertise in cellular modeling. You will support the research team in elucidating mechanisms of microglia modulation and their contribution to neurodegenerative diseases. You will have access to state-of-the-art cellular models as well as proprietary tools to modulate targets of interest, aiming at elucidating signaling mechanisms involved in the biology of neuroinflammation. In this position you will be supported by mentors with diverse educational backgrounds, scientific and technical expertise, and drug development experience. In addition, there is a unique opportunity to collaborate with cross-functional teams and scientists from other departments and you will have opportunities to gain insights into aspects of drug development. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Major accountabilities: As a Discovery Postdoctoral Fellow, you will: Independently design and develop cellular assays to study mechanisms and functional consequences of microglia target modulation Study intra-, extra- and intercellular signaling pathways in appropriate cellular models using a battery of available tools and analytical methods Work closely with experimental teams within the group and across departments Communicate your work in a clear manner to both experts and non-experts in the field Prepare and present research findings in scientific publications and conferences Minimum Requirements: PhD in Neuroscience Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Good knowledge in microglia biology and specific interest studying neuro-glia cross talk In-depth understanding of the current knowledge on disease pathology of neurodegenerative disorders (e.g. AD, PD, ALS, MS) Solid experience working with complex cell culture models such as primary mouse neuronal cultures and hiPSC-derived cells or generate stable genetically engineered cell lines Some basic computational experience is a plus Some experience with in vivo models and ex vivo analysis techniques is a plus Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054856 Jun 11, 2025 Switzerland Summary Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our Neuroinflammation team within the Neuroscience Research Department in Basel, Switzerland. About the Role We are seeking an independent, highly motivated and dedicated researcher with substantial background and knowledge in neuroinflammation, microglia biology and advanced technical expertise in cellular modeling. You will support the research team in elucidating mechanisms of microglia modulation and their contribution to neurodegenerative diseases. You will have access to state-of-the-art cellular models as well as proprietary tools to modulate targets of interest, aiming at elucidating signaling mechanisms involved in the biology of neuroinflammation. In this position you will be supported by mentors with diverse educational backgrounds, scientific and technical expertise, and drug development experience. In addition, there is a unique opportunity to collaborate with cross-functional teams and scientists from other departments and you will have opportunities to gain insights into aspects of drug development. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Major accountabilities: As a Discovery Postdoctoral Fellow, you will: Independently design and develop cellular assays to study mechanisms and functional consequences of microglia target modulation Study intra-, extra- and intercellular signaling pathways in appropriate cellular models using a battery of available tools and analytical methods Work closely with experimental teams within the group and across departments Communicate your work in a clear manner to both experts and non-experts in the field Prepare and present research findings in scientific publications and conferences Minimum Requirements: PhD in Neuroscience Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Good knowledge in microglia biology and specific interest studying neuro-glia cross talk In-depth understanding of the current knowledge on disease pathology of neurodegenerative disorders (e.g. AD, PD, ALS, MS) Solid experience working with complex cell culture models such as primary mouse neuronal cultures and hiPSC-derived cells or generate stable genetically engineered cell lines Some basic computational experience is a plus Some experience with in vivo models and ex vivo analysis techniques is a plus Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com, and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary The Global Program Clinical Head (GPCH) in CVM is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy About the Role Major accountabilities: Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on Biomedical Research clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-DDP, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. Minimum requirements: What you’ll bring to the role: MD or equivalent (preferred) PhD, or PharmD degree required 6 years professional experience with (MD or equivalent) OR 10 years (PhD or PharmD) of involvement in clinical research or drug development in an industry environment spanning clinical activities in Phases I through III/IV, including submission dossiers required Cardiovascular disease expertise, ideally experience with Cardio-Immunology or inflammasome Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Experience with submissions and health authorities required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Associate Director, Data & AI leads the development of data and AI strategy, and activities focused on delivering value to programs in Novartis development. The AD will utilize their expertise in drug development, scientific knowledge and background on the disease and therapies, and technical leadership in data science and AI to drive and lead interdisciplinary collaborations and decision making for assigned projects. Demonstrating high levels of independence in support of complex projects, they are responsible for collaborating with the clinical development team and members of the program team and across the organization more broadly, as well as identifying external partners to drive project execution by leveraging external innovation and resources. Works with the function leads and teams in developing, leading and implementing key projects within the group and cross-functionally with partners efficiently and consistently to enable Development priorities and meet compliance standards. May serve as on programs as a local manager of a small team or Individual contributor who is a thought leader with deep technical knowledge in data science, AI and machine learning, scientific knowledge and fluency, experience with drug development framework, stage gates and steps for advancing programs through registration.. Specifically, be the primary contact for data and AI, contributing to the data strategy, and support such projects in close collaboration with internal and external stakeholders e.g. program teams, clinical development teams, Precision Medicine, data42 and analytics. About the Role Major accountabilities: Lead data and AI projects for the Data Design & Clinical Innovation team Actively lead or participate in the identification of data gaps for scientific and clinical needs in clinical development in one or more therapeutic areas, and in the development and implementation of strategic solutions to these gaps for example: Evaluate the data quality from internal and external data sources for DDCI projects Collaborate with internal stakeholders to bring in external data to internal data platform Evaluate and implement AI solutions to improve the efficiency and effectiveness of clinical development programs Collaborate with data science groups to support the implementation of use cases and help identify work flows and techniques that may be reproducible Bridges scientific, technical, and drug development expertise to engage with clinical leads in CD, program teams, disease units, analytics, regulatory and commercial for data science and AI approaches Partner with Analytics and other Data Science organizations to plan and implement training and coaching in order to drive a culture of data and AI literacy and innovations to drive clinical development success. Track data science and AI projects within DDCI requiring inputs and support Scope and evaluate data science and AI technology solutions for drug development Ensure data transformation and analysis specifications to ensure completeness, correctness and adherence to department guidelines and SOPs as well as to applicable GxP requirements Minimum Requirements: PhD (essential), Post Doc (desired) in data science, biostatistics, computational biology, bioengineering or related field 7 years of involvement in clinical research or drug development in an academic or industry environment. 5 years of contribution to and accomplishment in all aspects of data science, in a global/matrix environment in pharmaceutical industry Demonstrated ability to establish strong scientific partnership with key stakeholders Thorough knowledge of GCP, clinical trial design, statistical analysis methodology, and regulatory/clinical development process Scientific background in basic and clinical research with good understanding and knowledge on drug development. Strong skills in leading and managing cross-functional projects with significant (visible) business impact. Proficient in Python, SAS, R, and R-shiny; Building machine learning models utilizing high performance computing (HPC) environments Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Design, plan, perform, interpret and report results of scientific experiments for the preparation and timely delivery of drug substances (DS), drug products (DP), processes and procedures within a multifunctional project team coordinated by a Project Leader. Manage technical lab/plant activities. About the Role Your responsibilities include, but are not limited to: Developing efficient and scalable oligonucleotide processes for relevant projects within the Novartis portfolio, across various scales. Contributing to the Oligo team by developing and optimizing synthesis and purification methods used in process R&D. Generating and documenting reliable data to support oligonucleotide process development. Investigating diverse approaches to oligonucleotide synthesis and evaluating their potential using cutting-edge automated platforms. Ensuring the application of state-of-the-art technologies in all development activities. Utilizing laboratory resources efficiently to maximize productivity. Upholding high standards of laboratory and process safety. Co-authoring documentation required for process transfer to pilot plants. Acting as a consultant for troubleshooting during manufacturing campaigns. What you’ll bring to the role: A completed Master’s degree in Organic Chemistry is an advantage. Industrial experience with a focus on oligonucleotide synthesis. Hands-on experience in operating and maintaining state-of-the-art equipment, including oligo synthesizers, tangential flow filtration (TFF) systems, chromatography units, and lyophilizers. Advanced experience in programming methods for synthesizers and chromatography systems. Proficiency in common analytical techniques for oligonucleotides, including liquid chromatography (LC) and mass spectrometry (MS). Fluency in English. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10029778 May 19, 2025 Switzerland Summary As our Clinical Development Medical Director in our Immunology Development Unit you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. About the Role The Clinical Development Medical Director (CDMD) for Rheumatology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years- experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons. This hybrid role can be based in Basel, London, Barcelona, Madrid or Dublin. *R ead our handbook to learn about all the ways we-ll help you thrive personally and professionally: *Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Barcelona Gran Vía, Spain Alternative Location 2 Dublin (NOCC), Ireland Alternative Location 3 London (The Westworks), United Kingdom Alternative Location 4 Madrid Delegación, Spain Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10053278 Jun 10, 2025 Switzerland Summary We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. This applied research program is designed to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a fellow, you will learn to apply your quantitative and computational skills to make a difference for patients and reimagine medicine at Novartis. As part of the Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Drug hunting is a team sport, and you will gain experience in Data Science & AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Seize this chance to be at the forefront of Data Science and AI, and shape the future of drug discovery! This project aims to perform human genetics-driven target discovery for immunological diseases. The successful candidate will establish a pipeline of statistical and machine learning models to identify causal variants, map them to likely target genes, and describe potential underlying mechanisms. We will apply this pipeline to immune system-driven diseases to formulate clear hypotheses on novel drug targets and test them experimentally. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Data Science Innovation Postdoctoral Fellow, you will: Work independently as well as within interdisciplinary teams to drive your project Analysis, integration, and visualization of human genetics with complementary omics data Apply statistical and machine/deep learning methods to identify disease associated variants, their target genes and regulatory mechanism Analyze omics datasets to formulate and/or support hypotheses generated by ML models Effectively collaborate with wet lab scientists to validate in silico findings Role requirements : PhD in Genetics, Computational Biology or a related field (Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD, i.e. PhD degrees must have been awarded May 2023 or later). Excellent skills in computational and statistical analysis of genetics and omics data (GWAS, QTLS, transcriptomics and chromatin omics) Excellent skills in programming, data visualization and reproducible research in R/Bioconductor and/or Python Experience with machine/deep learning methods is considered a plus Experience in Immunology is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity #DSIF How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary #onsite Location: Basel, Switzerland Level: Principal Scientist II or Senior Principal Scientist Full time, onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis’ purpose. We are looking for a highly motivated and independent scientist with strong expertise in parallel purification and automation. You will be complementing our existing team of separation and analytical experts with your passion and experience in designing and implementing integrated and automated workflows for the purification of new and emerging modalities. The successful candidate will understand projects in the context of the overall process and will be integral to their success by taking a leadership role in providing customized solutions, thereby directly contributing to the discovery of new medicines! About the Role Your responsibilities will include, but are not limited to: Develop, implement, and oversee innovative solutions and workflows to advance parallel purification and analytics platforms that support diverse chemical modalities, including peptides, oligonucleotides, and low molecular weight (LMW) compounds Implement and maintain robust, scalable, high-throughput purification platforms for peptides and additional modalities at different scales and with associated analytical processes Refine and optimize ongoing library purification workflows. Collaborate with cross-disciplinary teams and external partners to adapt equipment and processes in response to changing needs. Work closely with cross-site and cross-functional partner groups to support harmonized digital workflows, hardware setups, and data integration. Drive data standardization and advance capabilities for active learning Lead and mentor a team of experienced scientists. Cultivate an environment of professional growth and scientific excellence, empowering team members to develop and deliver impactful results Anticipate emerging trends and future needs in automation solutions for purification and analytics. Drive forward-thinking strategies by working closely with chemists and project teams to enable cutting-edge solutions aligned with GDC’s evolving priorities Serve as a subject matter expert within the organization by sharing domain-specific expertise, introducing novel techniques, and fostering creativity and resourcefulness. Contribute to shaping the group’s strategic vision and future Actively participate in global internal and external scientific communities through presentations, publications, and professional networking What you will bring to the role: Science or engineering degree (PhD or Master’s) and at least 5 years of post-degree experience in automation and purification, ideally in a drug discovery setting State-of-the-art knowhow and recent hands-on experience in implementing automation solutions, including digital workflows (software/hardware), troubleshooting hardware systems, and proficiency with current data workflow and analysis software packages Demonstrated expertise in peptide purification; experience in oligonucleotide and low molecular weight compound processing is highly desirable Hands-on experience with Laboratory Information Management Systems (LIMS) to manage workflows, data tracking and analytical reporting in a high-throughput environment A track record of coaching, mentoring, and leading a team of scientists as well as in establishing and driving cross-site and interdisciplinary collaborations History of initiating and driving projects independently to completion, with strong organizational skills and attention to detail Exceptional collaboration and communication skills, ability to work effectively within a matrixed organization and build consensus across diverse teams and stakeholders Strong connections within external networks in the parallel purification and automation community are highly desirable Proficiency in English (written and spoken) is required Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053205 May 27, 2025 Switzerland Summary #onsite Location: Basel, Switzerland Level: Principal Scientist II or Senior Principal Scientist Full time, onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis- purpose. We are looking for a highly motivated and independent scientist with strong expertise in parallel purification and automation. You will be complementing our existing team of separation and analytical experts with your passion and experience in designing and implementing integrated and automated workflows for the purification of new and emerging modalities. The successful candidate will understand projects in the context of the overall process and will be integral to their success by taking a leadership role in providing customized solutions, thereby directly contributing to the discovery of new medicines! About the Role Your responsibilities will include, but are not limited to: Develop, implement, and oversee innovative solutions and workflows to advance parallel purification and analytics platforms that support diverse chemical modalities, including peptides, oligonucleotides, and low molecular weight (LMW) compounds Implement and maintain robust, scalable, high-throughput purification platforms for peptides and additional modalities at different scales and with associated analytical processes Refine and optimize ongoing library purification workflows. Collaborate with cross-disciplinary teams and external partners to adapt equipment and processes in response to changing needs. Work closely with cross-site and cross-functional partner groups to support harmonized digital workflows, hardware setups, and data integration. Drive data standardization and advance capabilities for active learning Lead and mentor a team of experienced scientists. Cultivate an environment of professional growth and scientific excellence, empowering team members to develop and deliver impactful results Anticipate emerging trends and future needs in automation solutions for purification and analytics. Drive forward-thinking strategies by working closely with chemists and project teams to enable cutting-edge solutions aligned with GDC-s evolving priorities Serve as a subject matter expert within the organization by sharing domain-specific expertise, introducing novel techniques, and fostering creativity and resourcefulness. Contribute to shaping the group-s strategic vision and future Actively participate in global internal and external scientific communities through presentations, publications, and professional networking What you will bring to the role: Science or engineering degree (PhD or Master-s) and at least 5 years of post-degree experience in automation and purification, ideally in a drug discovery setting State-of-the-art knowhow and recent hands-on experience in implementing automation solutions, including digital workflows (software/hardware), troubleshooting hardware systems, and proficiency with current data workflow and analysis software packages Demonstrated expertise in peptide purification; experience in oligonucleotide and low molecular weight compound processing is highly desirable Hands-on experience with Laboratory Information Management Systems (LIMS) to manage workflows, data tracking and analytical reporting in a high-throughput environment A track record of coaching, mentoring, and leading a team of scientists as well as in establishing and driving cross-site and interdisciplinary collaborations History of initiating and driving projects independently to completion, with strong organizational skills and attention to detail Exceptional collaboration and communication skills, ability to work effectively within a matrixed organization and build consensus across diverse teams and stakeholders Strong connections within external networks in the parallel purification and automation community are highly desirable Proficiency in English (written and spoken) is required Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a CDD in the CV TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements: • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred*** • Minimum of 7 years experience in clinical research or drug development • Working knowledge of the assigned disease area is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is the clinical leader of a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase), or a large, complex trial, under the leadership of the (Sr.) GPCH. About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051809 Jun 05, 2025 Switzerland Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. - 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we-ll help you thrive personally and professionally:- Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Diese Position ist eine leitende Funktion, die für das Management und die Überwachung der Tierhaltungseinrichtungen verantwortlich ist. Dazu gehört die operative Unterstützung der in den Tierhaltungen tätigen Personen sowie die Betreuung und Weiterentwicklung der Anlagen, Geräte und Ausstattung in einem multidisziplinären biomedizinischen Forschungsumfeld, dass sich über mehrere Gebäude erstreckt und mit verschiedenen Spezies arbeitet. Diese Rolle erfordert ausgeprägte Führungskompetenzen in interdisziplinären Teams und Matrixstrukturen, die Fähigkeit, mit verschiedenen Forschungsbereichen zu arbeiten, ausgezeichnete Kommunikations- und Organisationsfähigkeiten sowie ein starkes Engagement für den Tierschutz und die Bereitschaft, sich selbst und andere weiterzuentwickeln. About the Role Hauptaufgaben: Campusplanung: Sanierung und Optimierung der Tierhaltungsanlagen. Schnittstellenmanagement: Zwischen Novartis und Dienstleistern (ISS, CBRE, FMI, IOB). Überwachung und Optimierung der Käfigreinigung: Planung und Koordination von Schnittstellen, Abläufen, Anpassungs- und Optimierungsprojekten. Business Continuity: Anleitung und Überwachung des Facility Managements (CBRE) zur ständigen Sicherstellung der Medienversorgung und Umgebungsparameter in der Tierhaltung. Planung und Koordination der Umnutzung von in vivo Bereichen. Beratungsleistungen: Beratung zur Weiterentwicklung der Vivarium Operations Prozesse. Koordination von Reparaturen, Service und Wartung: Für tierhaltungsspezifische Anlagen und Geräte (z.B. IVC-Gebläse/Racks, Käfigwechselstationen) und die Gebäudeinfrastruktur. Evaluierung, Beschaffung und Lagerverwaltung von Material und Geräten für den Tierhaltungsbetrieb und die Versorgung der Versuchstiere. Ansprechpartner: Für CM und Forschungspartner (BR Labore), Unterstützung bei logistischen Angelegenheiten und Erarbeitung/Bereitstellung von Lösungen. Budgetangelegenheiten: Beitrag zu Tierhaltungs-Budgetfragen (z.B. Budgeterstellung, Bestellungen, Lieferungen). SOPs: Beitrag zur Erstellung und periodischen Überprüfung von CM-Betriebs-SOPs. Validierung neuer Technologien: Innerhalb der Tierhaltung. Mitglied von NEM-Basel und CM-Pikett Gruppe. Vertretungen und Personalmanagement: Head Vivarium Operations und VO-Supervisor für das Tierpflegepersonal (Verantwortung für die Führung und Entwicklung des tierpflegerischen Personals). Leistungsindikatoren: Kooperation mit dem Head VO zur Sicherstellung der Funktionstüchtigkeit aller tierhaltungsspezifischer Anlagen und Geräte, zur Gewähleistung einer «state-of-the-art» Arbeitsumgebung und zur optimalen Unterstützung des VO-Personals bei dessen verantwortungsvoller Versorgung und Pflege der Tiere gemäss höchsten tierschützerischen Massstäben. Beherrschung aller erforderlichen betrieblichen Fähigkeiten. Teamorientierung und Fähigkeit zu interaktivem Arbeiten. Fokussierung auf effiziente und konsistente Erledigung von Aufgaben. Einhaltung aller internen und externen Vorschriften gemäss dem «Guide for the Care and Use of Laboratory Animals». Kontinuierliche Weiterbildung und Wahrnehmung beruflicher Entwicklungsmöglichkeiten zur Verbesserung und Erweiterung relevanter persönlicher Fähigkeiten und Kenntnisse. Zusammenarbeit mit in vivo Forschenden zur Erreichung wissenschaftlicher Ziele. Identifizierung von Prozessineffizienzen vor Ort, Optimierung von Prozessen und proaktive Entwicklung von Lösungen für betriebliche Herausforderungen sowie Optimierungen von Gebäuden und Infrastruktur. Beitrag zur Schulung neuer VO-Mitarbeitender nach Bedarf. Effektive Führung von Mitarbeitenden im Vertretungsfall. Anforderungen: Bildung: Bachelorabschluss in einer Naturwissenschaften oder eine gleichwertige Kombination aus Erfahrung und höherer Bildung erforderlich. Erfahrung: Nachgewiesene mehrjährige Erfahrung in einem Labortierprogramm erforderlich. Erfahrung in der Personalführung und/oder Teamleitung von Vorteil. Sprachen: Deutsch und Englisch erforderlich. Fähigkeiten und Kenntnisse: Fähigkeit zu sicherer und eloquenter Kommunikation über betriebliche Themen in der Abteilung und mit der Forschungsgemeinschaft sowie Schaffung einer zwischenmenschlich-konstruktiven und kollegialen Arbeitsatmosphäre. Starker Sinn für persönliche Verantwortung, Zuverlässigkeit und Integrität. Fähigkeit zur Identifizierung und Lösung von mitunter komplexen betrieblichen Herausforderungen in der Tierhaltung. Selbständiges und eigenverantwortliches Arbeiten bei gleichzeitiger Motivation des ganzen Teams. Fähigkeit zur Koordination von Übergangslösungen und Zeitplanänderungen. Sehr gute Kenntnisse in der Tierpflege und starke Verpflichtung zum Tierschutz. Engagement für die berufliche Entwicklung des Teams und kontinuierliches Lernen. Zusätzliche Anforderungen: Fähigkeit, 20 kg zu heben, schwere Gegenstände zu bewegen, längere Zeit im Stehen zu arbeiten und repetitive Bewegungsaufgaben auszuführen. Bereitschaft zur Unterstützung an Wochenenden, Feiertagen und als Pikettdienst. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: As Senior Expert / Functional Lead (FL) you will play a key role in the development of formulations and processes for Biologic Drug Products (e.g. therapeutic proteins, conjugates and other new modalities) for clinical or commercial use. You will be working in an international team, located at our headquarters in Basel, Switzerland, focusing on pharmaceutical development of innovative biologic drug products to help bring new treatments to patients and global markets around the word. Apply now to join our dynamic team! About the Role Your responsibilities: As Functional Lead you will lead, own and drive all deliverables within complex Biologic Drug Product development projects and you will be a core member of the Drug Product development sub-team, representing the scientific and technical excellence. Your responsibilities as Functional Lead will be to: Independently design, plan, supervise and/or execute technical and scientific activities for the assigned project(s) in close alignment with the respective project manager(s) and in close collaboration with the lab scientist(s). Interpret results from scientific / technical activities including drawing relevant conclusions and presentation of data to relevant sub-teams as required. You will deliver development work packages to meet agreed objectives & timelines in the project team and you will ensure and drive the information exchange in the Drug Product sub-team. Plan, prepare and provide required information for clinical Drug Product supplies to the clinical manufacturing sites internally or externally with support of project leader. Furthermore, you will support technical and clinical manufacturing campaigns throughout the development phases of the assigned project(s) with technical expertise on formulation and process. Drive and support Root Cause Investigations (RCIs) as well as trouble shooting activities including development of solutions, mitigation plans and report risks or issues to the project manager and/or any other relevant team member or line unit. Write and review key development documents and reports which are used to prepare regulatory CMC documents. Furthermore, you will support reviews of regulatory CMC documents and contribute to interactions with health authorities. In your role as Functional Lead, you will further support the Drug Product Science Team with the following responsibilities. Lead or contribute to key scientific initiatives and workstreams to develop short- & long-term drug product development strategies for the Biologics pipeline. Lead or contribute to innovation initiatives with strong focus on implementation of data & digital in our daily development work. Present scientific or technical results to different audiences within or external to Novartis. Work according to appropriate laboratory standards for quality, ethics, health, safety, environment protection and information security. What you’ll bring to the role: Ph.D. in Chemical or Biochemical Engineering, Pharmaceutical Technology, or equivalent. 2-5 years of experience in biotech / pharma industry with emphasis on biologic drug product formulation and process development, manufacturing, scale-up and technology transfer. Ideally strong knowledge and experience in development of formulations and processes for special protein deliveries as well as for highly concentrated protein formulations. Proven track record in resolving technical issues as well as strong track record in Innovation and Scientific topics. Highly structured and organized working style. Proven track record for working independently in development laboratory environment including knowledge HSE requirements for development laboratories. Good understanding of data integrity requirements in development environment. Solid understanding of quality principles in biologic drug product development. Experience in Good Manufacturing Practice (GMP) environment and/or GMP systems is an advantage. Interest and passion in data & digital topics, e.g. data analysis, data science, process modeling and automation. Strong knowledge in statistical data analysis and skills in data presentation. Basic knowledge in programming (e.g. Python, R) as well as basic knowledge and experience in process modeling (e.g. mixing processes) is an advantage. Interdisciplinary thinking and proven ability to work in cross-functional international teams. Strong presentation skills and scientific/technical writing skills. Good written and verbal communication skills. Proficient in English – spoken and written. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: As Senior Expert / Functional Lead (FL) you will play a key role in the development of formulations and processes for Biologic Drug Products (e.g. therapeutic proteins, conjugates and other new modalities) for clinical or commercial use. You will be working in an international team, located at our headquarters in Basel, Switzerland, focusing on pharmaceutical development of innovative biologic drug products to help bring new treatments to patients and global markets around the word. Apply now to join our dynamic team! About the Role Your responsibilities: As Functional Lead you will lead, own and drive all deliverables within complex Biologic Drug Product development projects and you will be a core member of the Drug Product development sub-team, representing the scientific and technical excellence. Your responsibilities as Functional Lead will be to: Independently design, plan, supervise and/or execute technical and scientific activities for the assigned project(s) in close alignment with the respective project manager(s) and in close collaboration with the lab scientist(s). Interpret results from scientific / technical activities including drawing relevant conclusions and presentation of data to relevant sub-teams as required. You will deliver development work packages to meet agreed objectives & timelines in the project team and you will ensure and drive the information exchange in the Drug Product sub-team. Plan, prepare and provide required information for clinical Drug Product supplies to the clinical manufacturing sites internally or externally with support of project leader. Furthermore, you will support technical and clinical manufacturing campaigns throughout the development phases of the assigned project(s) with technical expertise on formulation and process. Drive and support Root Cause Investigations (RCIs) as well as trouble shooting activities including development of solutions, mitigation plans and report risks or issues to the project manager and/or any other relevant team member or line unit. Write and review key development documents and reports which are used to prepare regulatory CMC documents. Furthermore, you will support reviews of regulatory CMC documents and contribute to interactions with health authorities. In your role as Functional Lead, you will further support the Drug Product Science Team with the following responsibilities. Lead or contribute to key scientific initiatives and workstreams to develop short- & long-term drug product development strategies for the Biologics pipeline. Lead or contribute to innovation initiatives with strong focus on implementation of data & digital in our daily development work. Present scientific or technical results to different audiences within or external to Novartis. Work according to appropriate laboratory standards for quality, ethics, health, safety, environment protection and information security. What you’ll bring to the role: Ph.D. in Chemical or Biochemical Engineering, Pharmaceutical Technology, or equivalent. 2-5 years of experience in biotech / pharma industry with emphasis on biologic drug product formulation and process development, manufacturing, scale-up and technology transfer. Ideally strong knowledge and experience in development of formulations and processes for special protein deliveries as well as for highly concentrated protein formulations. Proven track record in resolving technical issues as well as strong track record in Innovation and Scientific topics. Highly structured and organized working style. Proven track record for working independently in development laboratory environment including knowledge HSE requirements for development laboratories. Good understanding of data integrity requirements in development environment. Solid understanding of quality principles in biologic drug product development. Experience in Good Manufacturing Practice (GMP) environment and/or GMP systems is an advantage. Interest and passion in data & digital topics, e.g. data analysis, data science, process modeling and automation. Strong knowledge in statistical data analysis and skills in data presentation. Basic knowledge in programming (e.g. Python, R) as well as basic knowledge and experience in process modeling (e.g. mixing processes) is an advantage. Interdisciplinary thinking and proven ability to work in cross-functional international teams. Strong presentation skills and scientific/technical writing skills. Good written and verbal communication skills. Proficient in English – spoken and written. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you ready to lead with excellence and make a significant impact on our company's safety surveillance strategy? We are looking for a dynamic and strong people manager to design and develop our safety surveillance strategy for product approval. Join us and be the driving force behind our commitment to safety and excellence! About the Role Major accountabilities: Manage an efficient and successful disease area within the Therapeutic Area (TA)/Development Unit (DU) Medical Safety organization, which provides robust medical and science-driven contribution to BenefitRisk evaluation throughout product lifecycle to enable Novartis to provide impactful medicines to patients worldwide. Enhance scientific and clinical experience of Medical Safety physicians / scientists through continuous training and coaching. Prepare safety objectives and evaluates and manages performance of the Medical Safety associates within the TA/DU. Identify talents and high potential associates and able to defend and discuss in front of leadership team. Together with associates identifies career development opportunities and support associates in the career path. Provide expert safety input to the clinical development program for assigned projects/products and be an active member of the Global Program Team (GPT), Global Clinical Team (GCT) and Clinical Trial Team (CTT). Responsible for safety issue management from formation of Global Program Team (GPT) through Life Cycle Management. Responsible for overall signal detection, monitoring, evaluation, interpretation and appropriate management of safety information, based on information from all relevant line functions, post-marketing data, and other sources. Responsible for documentation/tracking/record keeping of the assigned compounds medical safety activities Responsible for responses to inquiries from regulatory authorities or health care professionals on safety issues. Lead the preparation of the safety strategy for health authority responses and strategy, in collaboration with other project team members. Contribute to and often lead the development of departmental and functional/business unit goals and objectives. ​ Minimum Requirements: Medical Degree or equivalent (preferred), PhD, PharmD or equivalent graduate level health care professional degree required. Specialty Board certification desirable. Useful additional degrees: Post graduate degree in Pharmaceutical Medicine; Master of Public Health in Epidemiology (or equivalent). 5 years clinical experience postdoctoral. At least 7 years progressive experience in drug development in a major pharmaceutical company (of which 5 years in a global position), including 5 years in safety at a medical position. Expertise in preparing or contributing to preparation of clinical safety assessments and regulatory reports/submissions involving safety information – to include NDA submission documents. Strong experience in leading cross-functional, multicultural teams. Strong experience with (safety or others) issue management. Strong experience in drug development, clinical trial methodology, regulatory requirements, scientific methodology, statistics and writing of publication. Strong leadership skills including coaching, motivating, and directing, and fostering teamwork. Ability to develop and maintain effective working relationships with subordinates, superiors and peers. Desirable Experience: Strong negotiation and conflict management skills. Strong experience with medical writing and delivering high quality documents such as RMPs, PSURs. Languages : English. Additional languages are an advantage. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054880 Jun 25, 2025 Switzerland Summary The Clinical Development Medical Director (CDMD) is the clinical leader of a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase), or a large, complex trial, under the leadership of the (Sr.) GPCH. About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years- experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture&nbsp ; You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: The Analytical Expert designs and plans scientific experiments as well as report and interpret results/outcome in line with the overall Analytical R&D project strategy for Drug Substance(s) and Drug Product(s) in development. He ensures project knowledge generation and preparation/timely delivery of supplies with high quality and state of the art standards. He leads and manages assigned project / network activities / support/coach team members. Finally, he contributes to the analytical project strategy definition; drive scientific and operational excellence and thereby contribute to overall Novartis Technical R&D strategy and goals for New Chemical Entities (NCE). About the Role Analytical Research and Development (ARD) sits within Development / Technical R&D and plays an essential role in the characterization, analysis and control strategy definition of small molecules and synthetic large molecules Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to commercial production. We are looking for highly motivated Analytical Experts in the field of small molecules for oral administration focusing on early development including pre-clinical activities and/or late phase development, registration and launch preparation activities. Your responsibilities will include, but are not limited to: Designing, planning, supporting the execution as well as interpreting and reporting results of scientific experiments for the development and timely supply of drug substances (DS) and drug products (DP) intended for pre-clinical and clinical development as well as potential commercialization. Interpreting analytical data as well as authoring & reviewing supportive analytical documents (e.g analytical procedures, specifications, product characterization reports, validation protocols/reports, stability protocols/reports as well as batch records compilation and line function material disposition for stability and release testing) and aligning the corresponding activities within a global project team. Managing interactions with internal and external stakeholders, including outsourced activities to CROs by providing scientific and technical guidance whenever necessary. Proactively identifying scientific, technological and GMP challenges, propose creative solutions and communicate key issues to the appropriate management level and respective technical project team. Collaborate with the Analytical Project Leaders, analytical project team members, wider analytical community as well as partnering technical functions applying state of the art analytical science, technologies and processes. Working according to appropriate SOPs, GMP, Quality Directives, Health and Safety & internal Novartis guidelines. In order to successfully fulfill this role the analytical expert should bring the following qualifications: Minimum: Bachelor in analytical chemistry or equivalent with significant experience in analytical development of drugs. Desirable: Advanced degree in a relevant life science scientific area (e.g. Master, Ph.D. or equivalent in chemistry / pharmaceutical or analytical science). Preferably 5 years’ experience in the pharmaceutical industry with a track record in GMP activities for development or marketed products. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a global and highly dynamic environment. Advanced knowledge of analytical techniques and associated processes (e.g. HPLC and corresponding Chromatographic Data System, Dissolution rate, GxP Quality Management Systems, statistical evaluation tools ...). Additionally, considering that the activities will primarily focus on the development of oral dosage forms, knowledge in dissolution rate testing as well as drug substance solid state properties such as particle size distribution, solubility and polymorphism is essential. Good presentation skills and scientific/technical writing skills and associated IT Tools. Fluent in English (oral and writing), German is advantageous. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This internship offers an exciting opportunity for someone passionate about storytelling and communication. About the Role As part of the Live Magazine editorial and communications team, the intern will support the creation of engaging content for global newsletters, social media, and audio-based storytelling formats. Working closely with a cross-functional team, the role helps bring science-driven stories to life and ensures they resonate across digital platforms. Key Responsibilities Newsletter Support Draft and edit copy for our global newsletters. Help improve opening and click-through rates by testing new subject lines, formats, and visuals. Coordinate weekly editorial updates and align on content calendars. Support content distribution with the media monitoring team. Audiofication of Story Features Help identify which articles could be transformed into short audio content. Draft short scripts for voice-over or AI-based audio narration. Support the production process by coordinating transcripts and assets. Social Media Writing Write concise, compelling social posts (primarily LinkedIn and Instagram) to amplify feature stories. Work with designers and editorial staff to package content effectively for digital audiences. Maintain a clean and aligned content calendar across platforms. Editorial Maintenance & Quality Checks Perform weekly reviews of the live magazine site (in English and German) for typos and layout issues. Coordinate language-specific checks with Japanese, Chinese, and German colleagues. Ensure visuals are up-to-date and all links function properly. Admin & Content Management Maintain the editorial team’s vacation and publication calendar (Microsoft Teams). Help manage model release forms and patient consent contracts (via the ERC system). Keep the shared image repository updated (OneDrive). What You Bring Currently enrolled or recently graduated from University in the field of Communications, Journalism, Media, Marketing, or a related field. Interest in digital storytelling, social media, and/or audio formats. Strong written communication skills in English and German (Japanese, or Chinese a plus but not required). Ability to work independently, with attention to detail and a creative mindset. Basic familiarity with Microsoft Office (Outlook, Word, Teams). Familiarity with Adobe Suite, for editing podcasts and short video. Enthusiasm for learning and a collaborative spirit. What You’ll Gain Hands-on experience in global science communications. Exposure to editorial workflows and publishing processes. Opportunity to build a portfolio of social and newsletter content. Introduction to working with audio formats for storytelling. Mentorship from experienced writers and editors. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. This applied research program is designed to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a fellow, you will learn to apply your quantitative and computational skills to make a difference for patients and reimagine medicine at Novartis. As part of the Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Drug hunting is a team sport, and you will gain experience in Data Science & AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Seize this chance to be at the forefront of Data Science and AI, and shape the future of drug discovery! This project aims to perform human genetics-driven target discovery for immunological diseases. The successful candidate will establish a pipeline of statistical and machine learning models to identify causal variants, map them to likely target genes, and describe potential underlying mechanisms. We will apply this pipeline to immune system-driven diseases to formulate clear hypotheses on novel drug targets and test them experimentally. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Data Science Innovation Postdoctoral Fellow, you will: Work independently as well as within interdisciplinary teams to drive your project Analysis, integration, and visualization of human genetics with complementary omics data Apply statistical and machine/deep learning methods to identify disease associated variants, their target genes and regulatory mechanism Analyze omics datasets to formulate and/or support hypotheses generated by ML models Effectively collaborate with wet lab scientists to validate in silico findings Role requirements : PhD in Genetics, Computational Biology or a related field (Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD, i.e. PhD degrees must have been awarded May 2023 or later). Excellent skills in computational and statistical analysis of genetics and omics data (GWAS, QTLS, transcriptomics and chromatin omics) Excellent skills in programming, data visualization and reproducible research in R/Bioconductor and/or Python Experience with machine/deep learning methods is considered a plus Experience in Immunology is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity #DSIF How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As an expert in light microscopy you will join a core facility team as a consultant for researchers at Novartis Basel. You will also play a key part in supporting scientific projects by advising users, coordinating resource sharing, and contributing to the maintenance and optimization of microscopy infrastructure. About the Role Major accountabilities: Provide expert guidance to users and advanced users on all aspects of light microscopy experiments, including sample preparation, selection of microscopy modalities, and optimization of instrument settings. Support microscope owners in evaluating system performance and troubleshooting technical issues. Co-organize training sessions and educational programs in optics and microscopy. Stay up to date with emerging technologies; organize equipment demonstrations and provide strategic input for procurement decisions. Foster collaboration by connecting microscopy users across campus and helping to build a vibrant, engaged user community. Collaborate with image analysis specialists to assist researchers in the initial stages of image processing and data analysis Further capabilities: Practice efficient time management, focuses on deliverables, and is able to effectively prioritize. Analyze & communicate own results to department/project meetings. Provide input to internal/ external publications. Broaden technical knowledge via departmental activities, literature reading and experiential learning as well as attending conferences and workshops. Utilize established networks and builds new network connections, including outside of existing project team. Train members of lab and broader project team in familiar techniques. Education and Work Experience: PhD in Biology or Physics and 5 + years experience with high-end microscopy either as a post-doc or as a member of a microscopy facility or comparable qualifications Languages : excellent command / highly proficient in spoken and written English Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ulcerative colitis and Crohn's disease, along with other gastrointestinal ailments, represent a diverse array of conditions impacting millions globally. These afflictions have significant unmet medical needs and often lead to a diminished quality of life. Novartis stands at the forefront of pharmaceutical innovation in immunology, leveraging advanced scientific research to develop transformative treatments that enhance patients' lives worldwide. We are seeking a Medical Director or Executive Director of Gastrointestinal (GI) Immunology in Translational Medicine Immunology. Join us in this endeavor! You will provide medical and scientific leadership and expertise in a role that significantly impacts the drug development pipeline. 1. Drive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP) 2. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. 3. Support Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. 4. Provide scientific expert assessments and support for in-licensing opportunities, including due diligences. About the Role Major Accountabilities Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with TM TA Head and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Convene relevant (internal and external) experts to consider the proposed approach to reach TDP; present plans for approval at relevant decision boards. Be responsible for clinical portions of the Integrated Development Plan (IDP, including the Clinical Development Plan and Clinical Profiling Plan) Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Late-stage clinical projects (post-TDP, “Profiling”): In collaboration with TM TA Head or Translational Medicine Profiling Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. Drive analysis of studies and presents results to relevant decision boards. Communicate clinical team matters to GPTs and relevant BR and Development boards [and other Novartis Boards] Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Be responsible for writing TM portion of documents needed for regulatory submission through drug registration (including advisory committee and scientific advice group meetings) Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with TM TA Head, BR Research scientists, other TM line functions (BMD, CS&I, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities. This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Be accountable for compound-related biomarker strategies; works closely with Biomarker Expert in implementation. Business Development and Licensing (BD&L; in-licensing and outlicensing compounds): Participate on BD&L teams as the TM representative. In collaboration with BD&L team, evaluate the risks and benefits of potential in-licensing opportunities, identifying the strengths and weaknesses of external programs in terms of TM’s scope of responsibility. Participate in teams carrying out out-licensing of BR programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. Leadership: Lead study-specific teams/ clinical trial teams in partnership with other line functions. Lead BR-sub-team(s) on Global Project Teams for late-phase programs Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Man- agement) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific stand- ards and innovation. Key Performance Indicators Delivery of proposed Development Candidate ((B)DC) and Integrated Development Plan Approval (IDPA) milestones, and results driving decision-making for/against transition into later phase development (TDP), according to defined timelines. Delivery of Clinical pharmacology and profiling strategy including execution of studies according to timelines to support regulatory submissions and approvals. Delivery of TR plans, whether in vitro, in vivo, or in silico, to drive program strategy and clinical trial efficiency. Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results and a focus on operational excellence at all levels. Strong adherence to and modeling of Novartis values and behaviors. Impact of this role? Design and implementation of early Integrated Develop- ment Plan (IDP) and design and implementation of studies according to the IDP, enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds. This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the TDP mechanism, and driving the program after TDP by delivering key Profiling data to support regulatory submissions. Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis. Role Requirements : Education Doctoral degree, MD required in most cases. PhD or relevant scientific experience with academic track record preferred Demonstrated excellence and clinical expertise in relevant medical subspecialty. Experience/Professional Requirement: At least 5 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with level of role. Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. Demonstrated passion for science. Recognized expert in field, driving success for individual studies and projects; respected by colleagues across R&D, Development, and externally. Languages: Fluent English (oral and written). ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051970 May 21, 2025 Switzerland Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process Good knowledge of oncology and experience in early clinical development preferred. Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10054184 Jun 04, 2025 Switzerland Summary -Equipment Operator -Execute assigned manufacturing tasks and activities according to production schedule to enable the timely production of product with the quality and quantity in compliance with the relevant GMP, safety and environmental guidelines. -Service Operator -Execute assigned manufacturing tasks and activities according to production schedule in compliance with the relevant GMP, safety and environmental guidelines.Perform routine operational support activities according the manufacturing process and schedule and enable the timely production of product with the quality and quantity -Documentation Specialist Admin -The Documentation Specialist Admin manages the modification, editing, distribution, review and archiving of GMP manufacturing documents and the edition of the Batch records in order to deliver them to Production in the quality and within the deadlines. The Documentation Specialist Admin ensures a set of administrative tasks necessary for the proper functioning of the unit. About the Role Major accountabilities: Equipment Operator -Participation to the manufacturing processes -Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines. Key performance indicators: Deadlines: compliance with production planning, execution of tasks on time -Quality: Amount of errors in production documents edited or updated and in batch record review -Time management for shop floor where required Minimum Requirements: Work Experience: Operations Management and Execution. Collaborating across boundaries. Functional Breadth. Skills: Transportation. General HSE Knowledge. Knowledge of GMP. Art Curator. Transportation Classification (i.e. IATA or DOT) expertise. Manufacturing Process Execution. Languages : German Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary -Equipment Operator -Execute assigned manufacturing tasks and activities according to production schedule to enable the timely production of product with the quality and quantity in compliance with the relevant GMP, safety and environmental guidelines. -Service Operator -Execute assigned manufacturing tasks and activities according to production schedule in compliance with the relevant GMP, safety and environmental guidelines.Perform routine operational support activities according the manufacturing process and schedule and enable the timely production of product with the quality and quantity -Documentation Specialist Admin -The Documentation Specialist Admin manages the modification, editing, distribution, review and archiving of GMP manufacturing documents and the edition of the Batch records in order to deliver them to Production in the quality and within the deadlines. The Documentation Specialist Admin ensures a set of administrative tasks necessary for the proper functioning of the unit. About the Role Major accountabilities: Equipment Operator -Participation to the manufacturing processes -Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines. Key performance indicators: Deadlines: compliance with production planning, execution of tasks on time -Quality: Amount of errors in production documents edited or updated and in batch record review -Time management for shop floor where required Minimum Requirements: Work Experience: Operations Management and Execution. Collaborating across boundaries. Functional Breadth. Skills: Transportation. General HSE Knowledge. Knowledge of GMP. Art Curator. Transportation Classification (i.e. IATA or DOT) expertise. Manufacturing Process Execution. Languages : German Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Tätigkeitsbeschreibung • Unterstützung bei Internen und externen Audits • Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung • Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten • Genehmigungen für Wartung/Kalibrierung/Projekte einholen • Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren • Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten • Aktualisierung des computerisierten Wartungsmanagementsystems (SAP) nach Abschluss der Wartung/Kalibrierung • Dokumentation der Ausführung der Kalibrierung • Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich • Angewandte Geschäftseinblicke • Digitales & technisches Know-how • Betriebliche Exzellenz • Projekt-Exzellenz Bildungsabschluss • Abgeschlossene Berufslehre als Automatiker • Business-Networking • SAP • Software-Fehlerbehebung • Kenntnisse über GMP • Gesamte produktive Instandhaltung • Allgemeines HSE-Wissen Sprachen Fliessende Englischkenntnisse und Beherrschung der Landessprache Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary •Gerätebediener •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. •Service-Operator •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität •Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You’ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. WhyNovartis? 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards