Novartis AG

Job ID REQ-10059981 Sep 09, 2025 Switzerland Summary Accountable for all country clinical/medical aspects associated with programs/trials by providing clinical strategic and tactical leadership Gathers, informs, and acts on clinical/medical/scientific insights for clinical trial concept sheets/protocols, Informed Consent Forms (ICFs) and other relevant clinical documents to optimize clinical trial implementation. Drives the identification and involvement of qualified investigators with greatest recruitment potential, identifies clinical recruitment hurdles and drives clinical recruitment activities to overcome these hurdles. Accountable for adherence to safety standards and clinical data quality in the country by providing general clinical/medical support for trial related safety findings. In close collaboration with other line functions (e.g., clinical trial operations, Medical Affairs and Patient Engagement) actively contributes to successful allocation, fast clinical trial start-up, timely recruitment, early identification of potential delays, and development and implementation of mitigation plans. About the Role Provides Clinical Development and indication expertise specific to Country, and together with the clinical trial operations team, drives the execution of clinical trials with high quality and within planned time- lines: Validates study designs, is accountable for, and makes the final decision on the clinical/medical trial and program feasibility of implementing a clinical trial protocol based on medical/clinical practice and analysis of the competitive environment in the country. Provides clinical/medical expertise to clinical trial operations team members and clinical trial sites for Institutional Review Boards (IRB)/ Ethics Committee (EC) interactions. Decides on site/Country-specific scientific/clinical/medical content of the Informed Consent Form (ICF) as needed and ensures appropriateness of patient suitable language. Provides scientific/clinical/medical expertise during interactions with Country external Experts (e.g., Regulatory Authorities, Medical Experts, Advisory Boards, Patient Advocacy Groups, etc.). Develops clinical/medical trial plans taking the broader ecosystem into account for assigned pro- grams/trials to ensure successful trial implementation, which includes: Provides robust indication, compound, and protocol training: Leverages innovation in clinical trial planning and decides on clinical/medical recruitment strategy and implementation based upon physician interviews, analysis of competitive trials, and patient engagement. Gathers, informs, and acts on insights from clinical trial Investigators/site staff, Medical Experts, patients, and payers, with internal Stakeholders at the Country level with the goal to optimize clinical trial implementation. Supports planning, implementation, and follow-up of scientific/clinical/medical components of Regulatory Authority inspections and internal audits. Reviews and resolves Country trial-related scientific/clinical/medical issues/questions. If necessary, initiates the discussion with the Global Clinical Development team. Accountable for adherence to safety standards, clinical data quality for the Country and pro- vides general scientific/clinical/medical support for safety issues: Supports the Global Clinical Development team as needed to address/clarify clinical/medical Protocol Deviations through follow-up with clinical trial sites. May support innovative study designs by identifying and conducting quality assessments of Country datasets (e.g., Registries, Electronic Health Records, Payer data, Real World Data, etc.). Role Requirements Education & Experience MD/DO or equivalent, with training in cardiology preferred. Knowledge and clinical training in siRNA desirable Protocol Execution : Demonstrates a knowledge of how to adequately review and read a protocol to understand specifics of study design and answer questions regarding the trial. Applies a detailed understanding of the drug in question to provide medical context as it relates to disease processes, populations, and standards of care. Ability to assess the feasibility of implementing the protocol based on Country medical practice and sound understanding of the overall Clinical Development Plan. Demonstrates a high level of understanding of the protocol to train others, including site personnel. Demonstrates an understanding of the protocol to evaluate compliance on the part of the Investigator/site staff/study participant and any patient safety issues. Demonstrates an understanding of Regulatory requirements and internal policies, procedures, and guidelines pertaining to clinical trials. Demonstrates current knowledge of relevant Country regulations and compliance requirements and communicates to Global teams as required.Demonstrates knowledge of applicable SOPs, policies, procedures, and guidance documents. Expertise to represent the company as safety expert for clinical trials to external Regulatory and compliance bodies such as Regulatory Authorities, Health Boards, and REB/EC. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. *R ead our handbook to learn about all the ways we-ll help you thrive personally and professionally: *Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary #LI-Hybrid Location: Basel, Switzerland or Dublin, Ireland. Data42 is Novartis’s data and analytics platform, that allows us to integrate different data modalities (discovery, preclinical, clinical, Real World Data (RWD)) at scale to support data-driven decision making across Novartis. We are seeking a Head of Data Engineering and Data Products to join our dynamic and innovative data and analytics team. This pivotal role is responsible for designing, building and maintaining data solutions using Palantir Foundry. In this role you will foster the use of AI/GenAI to advance the speed of high quality data delivery as well as to democratize the access to data and insights across the organization. The Head of Data Engineering and Data Products is a member of the Data42 Leadership team which comprises a Head of Data Science and Innovation, a Head of Platform as well as a Data Governance lead. In addition, this role will collaborate with key stakeholders across the Data and Digital Organization and across Novartis to ensure the rapid delivery of high quality data and data products with a team of ~50 internal and external team members. You will contribute to the overall success of Data42 as a member of the Data42 Leadership Team. This role will report directly to the Global Head of Data42. About the Role Your responsibilities include but are not limited to: Data Engineering Define the vision, lead and continue to develop our cross-functional Data Engineering and Data Products team by staying current with emerging technologies Responsible for architecting, designing, maintaining and optimizing complex data pipelines to support data exploration, operational workflows as well as advanced analytics Ensure best practices for data ingestion, processing, validation, transformation and storage Implement processes that guarantee data quality, integrity, security, compliance, and discoverability across platforms Advance the further use of automation and AI to accelerate the quality, speed and breadth of data delivery Data Products Accountable for designing, building and running scalable data product solutions using agentic workflows on Palantir Foundry to democratize data access with future needs in mind. Establish and action security and compliance policies to safeguard data access and dissemination Collaborate across the Data and Digital Organization as well as across Novartis. Support and ensure the flexible co-ordination of activities to deliver against timelines Delivery and Operations: Define and track key measurements for data systems and product success Oversee the project planning, delivery, and ongoing support for data engineering and product development Drive continuous improvement by monitoring system performance, analyze product data, and respond to feedback Essential Requirements: PhD or master’s degree in computer science or a related discipline with experience in pharma R&D with more than 10-15 yrs of experience in pharma or biotech Experience in data management, data engineering and data modelling, particularly in the design and implementation of efficient and scalable data models across different data domains with Clinical and RWD experience preferred Knowledgeable and experienced in CDISC data models/standards (i.e. SEND, SDTM, ADaM) and RWD data models/standards (i.e. OMOP) Experience with cloud platforms and cloud-based data and AI/ML solutions (Databricks, Snowflake, AWD SageMaker etc…) Strong enterprise mindset strategic thinker with a vision for data-driven decision-making from an end-to-end perspective Proven global cross-functional leadership skills including coaching and talent development, with the ability to influence stakeholders and drive organizational change within complex and ambiguous environments Excellent communication skills with proficiency in English (oral and written) Nice to have: Ideally proficient in Palantir Foundry to integrate, manage and analyze large data-sets Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite ________________________________________ Be at the Forefront of Neuroscience Innovation Join Novartis and lead a world-class team driving breakthroughs in Neuroimmunology and Neuroscience. Shape the future of neuroscience by developing transformative therapies for diseases that impact millions worldwide. If you are passionate about scientific discovery, collaboration, and making a global impact, we want to hear from you. About the Role As Head of Neuroimmunology, you will design and direct preclinical strategies that have the potential to deliver blockbuster therapies and transform lives. Projects that modulate neuroimmunology targets and have the potential to treat the progression in multiple sclerosis and neurodegeneration. Neuroimmunology is a priority area for the Neuroscience franchise, and a pillar of the Neuroscience department. The Head of Neuroimmunology will deliver new projects and development candidates to the Biomedical Research pipeline which have the potential of becoming highly impactful drugs for diseases such Multiple Sclerosis, Alzheimer’s Disease, Parkinson’s disease, Frontotemporal dementia and ALS. Key Responsibilities Create, communicate and execute a collaborative vision and strategy for Neuroimmunological drug discovery and early development in focus areas including mechanisms of progression in multiple sclerosis, and other neurologic diseases including Alzheimer’s, Parkinson’s, Huntington’s disease and ALS Manage, mentor and coach a team of Senior associates, postdocs and Lab Heads delivering a portfolio of Neuroimmunology drug discovery programs, and modality agnostic development candidates for human trials (LMW, genetic medicines, biologics) Serve as the Basel site head for Neuroscience collaborating with the site heads for San Diego and Cambridge as a member of the Neuroscience leadership team, in addition to being the key leader in Basel for partner departments and functions including the Immunology Disease Area, DARe, Discovery Sciences, Discovery Chemistry and Biologics Research Build relevant state of the art in vitro and in vivo models of disease incorporating relevant immune and nervous system components, and a balanced and sustainable pipeline supporting the Novartis neuroscience strategy Build and maintain strong relationships externally, e.g. with global scientific medical research community (academia and biotech), and lead and identify relevant multi-party research alliances. Function as lead representative for BD&L efforts in scientific and strategic evaluation of neuroimmunology assets for partnering or acquisition Lead and/or contribute to ad-hoc initiatives aiming at improving Biomedical Research science Minimum Requirements PhD or MD in biomedical sciences, with post-doctoral fellowship. 15+ years of industry experience, including significant research/scientific leadership in neuroimmunology relevant research (academia or industry). Demonstrated experience in bringing multiple modalities (LMW, oligonucleotides, biologics, genetic medicines) from discovery into clinical development. Proven track record in leading multi-party, international collaborations. Major scientific accomplishments, including high-impact publications and a successful drug discovery record. Fluent in English (oral and written). German language would be advantageous. Strong coaching, mentoring, and people management skills. Experience in evaluating in-licensing opportunities and conducting due diligence as required. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The International Value & Access (V&A) Director, ASCVD, is responsible for co-developing innovative and winning market access strategies, optimizing the payer value proposition and access-relevant evidence packages for Atherosclerotic Cardiovascular Disease (ASCVD) asset(s). The Director will develop and implement transformative access solutions supporting the ASCVD disease area, maximizing the value of ASCVD assets across priority geographic markets (CN, DE, JP), major HTA archetypes (e.g., UK/CAN), and Budget Impact archetypes (e.g., Italy/Spain). The Director will also ensure timely and high-quality access inputs into Integrated Evidence Plans (IEPs), Integrated Product Strategies (IPS), and asset maximization efforts, fostering collaboration internally and externally to drive innovation and shape the future of ASCVD care. The role may require that launch/in-line asset payer evidence requirements and access needs are shared in follow-on, pipeline asset Target Product Profiles (TPPs), clinical development plans, and integrated product strategies. About the Role Key Responsibilities: Develop and operationalize the Integrated Product Access Strategy (IPAS) for ASCVD asset(s), creating and championing a compelling and competitive international strategic vision to enable successful access and reimbursement across key markets. Collaborate across cross-functional partners (TA, Pricing, HEOR, PCO, Development, and Commercial) to ensure ASCVD asset differentiation is clearly defined, and evidence packages meet payer, patient, and healthcare system expectations. Ensure that at launch, ASCVD asset(s) are supported by a robust payer value proposition —including a clear “value for money” story, a strong evidence package, and a pricing strategy maximizing both brand value and patient access. Guide the development of HEOR deliverables (e.g., cost-effectiveness models, budget impact models, real-world evidence plans, and quality-of-life studies) to support international and local access needs. Collaborate with the HEOR & Pricing teams to integrate evidence and pricing considerations into the access strategy, ensuring relevance to priority markets. Define payer evidence requirements and anticipate access opportunities and risks in key Tier 1 and Top 11 markets.Develop and provide a comprehensive “ access toolbox ” to guide local market access activities, pricing submissions, and payer negotiations. Partner with Clinical and Development teams to ensure access considerations are embedded in ASCVD asset later-stage clinical program, indication sequencing, and life-cycle management. Stay abreast of internal and external developments, health policy trends, and payer expectations in major HTA and budget impact archetypes to anticipate market evolution and inform strategic decisions. Collaborate with internal policy and development functions to ensure consistent, access-optimal approaches to shaping ASCVD asset’s value story and evidence generation.Disseminate ASCVD asset’s health system value and patient benefit through international fora, publications, and policy partnerships where appropriate. Lead and manage the International Access community , ensuring collaboration, knowledge sharing, and strategic alignment across regions and countries. Essential requirements: 5+ years of experience in market access, pricing, or HEOR roles within the pharmaceutical industry. 2+ years of international or ex-US regional experience . Experience working early in the drug development lifecycle and integrating access needs into development plans. Proven product launch experience , ideally in a cardiovascular or metabolic therapeutic area. Demonstrated ability to influence and collaborate across cross-functional, matrixed organizations. Expertise in access, pricing, or HEOR strategy development and execution. Desirable requirements: Advanced degree (MBA, Ph.D., M.D., Pharm.D., or M.Sc. in Health Economics or related field). Experience in cardiovascular or chronic disease therapeutic areas. 7+ years of experience in market access or related functions. 5+ years of international or ex-US experience; ex-US country launch experience strongly preferred. Location: This role is based in Basel, Switzerland Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Location: Basel Switzerland or East Hanover NJ / Cambridge MA. If applying in the US, please refer to REQ-10066635. LI-#hybrid The Strategy & Growth Portfolio Insights Forecasting team is seeking a new Director of Forecasting Excellence. This individual will oversee and assess transparent, evidence-based long-term forecasts and assumptions, including both modelling and the ability to generate and validate insights to support key assumptions, across the oncology solid tumor therapy area. The Director will also be able to synthesize key risk and opportunities in commercial assessments across programs and the portfolio. About the Role Key responsibilities: Is the subject matter expert in long-term revenue forecasting in Oncology Solid Tumor therapy area Develops and maintains indication-specific and epidemiology-based sales forecasts for pipeline and in-market brands on both an as needed and evolving basis Works collaboratively with the Strategy & Growth (S&G), US and International (INT) teams, as well as other cross-functional partners, to ensure market insights are integrated into forecasts, and US & INT numbers rolled into a single set of brand numbers Coordinates with and obtains alignment from key stakeholders, including US & INT, on critical assumptions and generating and aligning on the treatment journey. Identifies key risks and opportunities inherent in the forecast and employs appropriate methodologies for addressing and communicating these. Monitors the industry to remain informed of best practices, identifies opportunities to leverage new techniques and technologies that will enhance modelling and forecasting capabilities Consolidates and summarizes sales forecast assumptions, methodology, and results to all relevant systems and platforms Provides forecast models, assumption guidance, and training to S&G, US, INT colleagues and priority country teams Coaches and mentors junior colleagues Essential Requirements: Education : Bachelor’s degree in Science/Economics/ Statistics/Engineering/Business/related field required; MBA or advanced degree in one or more fields strongly preferred. Languages: Fluent oral and written English, other language(s) are an additional asset Experience/Professional requirement: Minimum 7 years of experience in Biotech/Pharmaceutical industry, life sciences consulting with commercial assessment experience; in-market commercial, finance, or new product planning experience strongly preferred Direct experience in assessing and forecasting oncology solid tumor projects Familiarity with epidemiology sources, IQVIA, Evaluate Pharma, claims, and other standard pharmaceutical data Experience incorporating big data analytics, competitive intelligence, primary & secondary market research into forecast models Comfortable with identifying and implementing AI solutions where appropriate Strong understanding of forecast methodologies, including expertise in patient-based forecast modelling, risk simulation (i.e. monte carlo) Expertise in translating inputs from cross-functional business partners into forecast model assumptions Demonstrated ability to work independently with minimal direction Strong project management skills, with the ability to manage multiple projects simultaneously Effective team building and consulting skills, with demonstrated ability to work collaboratively in cross-functional teams Excellent written, verbal, and presentation skills Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director – Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary To provide strategic, medical and scientific guidance and leadership for the development of multiple experimental agents in the Translational Clinical Oncology (TCO) portfolio beginning with input to early Target identification and continuing through to the Transition Decision Point. Formulate actionable development plans with the Development Organization to ensure rapid and seamless decision making and transitions of portfolio molecules and other assets. Provide scientific and clinical leadership to inform potential external innovative programs and business development in strategic areas of focus for the company. About the Role Key Responsibilities: Serve as an Early Clinical Development Area Leader for TCO, overseeing and implementing innovative clinical strategies for multiple molecules/assets that are advancing clinical testing in strategic indications, ensuring that robust and comprehensive development plans are in place and implemented. Oversee physicians (including direct reports and others) with strong mentorship and attention to ensure the strategic and operational aspects of their programs align with the overall oncology strategy and to foster their career development. Represent TCO programs and program strategy at governance boards in BR (e.g., TCO-Leadership Team (LT), Integrated Cancer Decision Board (ICDB), Discovery & Translational Board (DTB) and across the organization (e.g., Oncology Development Unit (ODU-LT), Therapeutic Area Leadership Team (TAL). Provide senior leadership and clinical input to clinical studies and pre-clinical research projects under their responsibility, effectively integrating their medical knowledge with expertise of colleagues in a wide range of other disciplines (e.g., Clinical Pharmacology, Biostatistics) to optimize the clinical development strategy, including supporting subsequent registration trials. Critically review and provide constructive feedback on documents for programs and studies under supervision including but not limited to protocol, Investigators Brochures (IBs), and health authority responses. Provide strategic input on internal and external assets and portfolio areas, representing TCO in Business Development and Licensing due diligence reviews and integrations. Lead or help oversee external collaborations, partnering closely with colleagues across the company. Play leadership roles in early development committees and initiatives by actively contributing strategic advice (e.g., the Study Concept Review Board and Protocol Review Committee). Apply medical knowledge to guide the safe, ethical and efficient conduct of own trials. Strive to maintain or exceed compliance obligations for Good Clinical Practice guidelines and Novartis Standard Operating Procedures. Liaise with outside experts, investigators, and regulatory authorities in oncology early clinical development First in Human (FIH) trials and represent projects to those groups and authorities. Write and review abstracts/manuscripts for presentation/publications at internal/external meetings. Mentor and serve as an educational resource and expert within Biomedical Research (BR) and across the organization. Essential Requirements: This hybrid position will be located at the Basel campus. This position will require 20-25% travel as defined by the business (domestic and/ or international). MD degree and PhD-level basic science required (PhD not required). MD / PhD preferred. Board-certification (or equivalent expertise) in Hematology-Oncology (heme-onc). Minimum 7 years’ experience leading complex global early phase hematology-oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. In case of no industry experience, substantially longer academic experience in translational hematology/oncology and substantial clinical study experience. Recognized as a Heme-Onc expert with a substantial record of quality scientific publications and international recognition for expertise. Interpretation of preclinical data in hematology/oncology (molecular biology, pharmacology, pharmacokinetics, and toxicology). Working knowledge of the application of PharmacoKinetics (PK) / PharmacoDynamics (PD) and biostatistics to clinical development and trials. Proven ability to analyze and interpret efficacy and safety data relating to oncology. Knowledge of Good Clinical Practices (GCP) and world-wide regulatory requirements relating to clinical trials and oncology. Excellent medical/scientific writing and oral communication/presentation skills. Proven ability to manage and develop a team. Outstanding scientific mentor; inspires others. Excellent personal ethical integrity and commitment to improving outcomes for patients with malignancies. #LI-hybrid Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland Are you a seasoned IP leader ready to shape the future of pharmaceutical innovation at a global scale? At Novartis, we’re seeking a Global Head of IP Transactions to lead high-energy and high-impact patent and IP diligence across more than 100 M&A and BD&L deals annually. This is a unique opportunity to influence strategic decisions, collaborate with top-tier legal and business teams, and drive IP excellence for the most transformative medicines in the world. Join us in a role where your expertise will directly support breakthrough therapies and deliver lasting value to patients and society. About the Role Key Responsibilities: Coordinates, manages, leads, and drives the IP diligence and strategy for transactions (M&A and BD&L), using the support of all enterprise, legal, and IP functions in the analysis of IP issues (patents, trademarks, trade secrets), resulting in proactive, timely, thorough, and comprehensive advice on all relevant issues. Ensures clear, well-communicated, and accurate IP advice for all M&A and BD&L deals, recognizing the time-sensitive nature of transactions requires constant attention also during non-standard working hours. Develops and drives the IP and regulatory transaction governance framework, establishes appropriate tools and processes, and leads high-visibility, complex global IP transactions projects. Advises the Global Head IP and the Global Head Legal Transactions, as well as other senior business leaders, on IP transactions and risk exposure, including strategies for minimizing adverse consequences. Builds strong interface with M&A/BD&L colleagues to ensure transactions are supported by IP staff trained and equipped to advise on all IP aspects of transactions and manages external counsel providing diligence information and contract clauses. Ensures exchange of information and know-how across the enterprise and provides training, with the goal that in-house and external lawyers take a consistent and proactive approach in effectively dealing with IP transactions, and that stakeholders are advised early and proactively of IP issues impacting the deal business cases. Leads the IP Transactions team, ensuring that their services are timely, proactive, targeted, and of high quality. Retains and develops key talents within IP, particularly in IP transactions. Member of IP Leadership Team (IPLT) and Transactions Legal Leadership Team (TLLT) Essential Requirements: Law school graduate (Common or Civil Law) with an additional science degree, Common Law and admission to the bar preferred; Patent attorney qualification required Extensive, multi-year IP transactions and diligence experience within a pharmaceutical company or with health care clients, including experience leading a team Sound knowledge of related following disciplines: Regulatory, Antitrust, and Contracts paired with a good understanding of Corporate, Tax Proven ability to deal positively when working under time pressure and with demanding clients as well as in handling a high volume of activity involving multiple, often complex projects simultaneously Proficiency in English (written and spoken), other languages are a plus Benefits and Rewards: Company Pension Plan, Life and Accidental Insurance, Meals Allowance or Canteen in the office, Flexible working hours. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity and Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: Act as Isotope Project Lead (IPL) by providing the specialist knowledge and expertise as Subject Matter Expert (SME) of radioisotope production and purification with particular focus on assessing, developing, and optimizing new technologies that support RLT products Life Cycle Management (LCM). Develop, optimize and transfer radioisotopes production and purification/separation processes. This is done in close collaboration with the relevant development centers, and Contract Manufacturing Organizations (CMOs). About the Role Major accountabilities: Manage inter functional project plan and budget using the Project Planning tool or System Identify issues and potential bottlenecks within projects and proposes options Contribute to the Radioisotope TRD-related activities. Ensure constant technological survey on the field of radioisotopes production. Apply scientific/technical expertise to identify new programs of interest for the company and support their development from early evaluation up late phase supply. Participate to development programs and activities around isotopes in adherence with global Isotope strategy and objectives within agreed timelines and budget, timely report key advancements and challenges. Identify strategic external partners for the activation of research collaboration agreement to develop new production technologies/ access to innovative isotopes. Implements strategic policies when selecting methods, techniques, and evaluation criteria for obtaining results. Establishes and assures adherence to budgets, schedules, work plans, and performance requirements. Represents area as core member in the Global Project Teams for defining global scientific strategy for development up to submission and approval in major markets of assigned product(s). Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable) Minimum Requirements: BSc. in Chemical Engineering, Pharmaceutical Technology, or equivalent scientific degree. Desirable MSc., PhD or equivalent experience. Desirable degree in Radiochemistry and strong scientific knowledge in nuclear medicine Successfully demonstrated several years (minimum of 5 years) of directly related experience in a scientific area or Ph.D. or equivalent Proven Project Leadership in all project phases Proven process understanding (Pharma, GMP, Validation and Regulatory aspects). Sound experience of data handling and applied statistics is a must. Strong understanding of risk assessment and risk management fundamentals/tools Quality-oriented with attention to detail Excellent verbal and written communication skills Excellent problem solving and decision-making skills Defining and implementing productivity improvement measures. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Are you energized by the challenge of transforming scientific innovation into life-changing therapies? Does the prospect of steering oral dosage form development, driving technical excellence, and leading projects with real business impact resonate with your ambitions? If you thrive in environments where experimental ingenuity meets strategic oversight—and where your communication and stakeholder management skills truly make a difference—then keep reading. Does this describe you? You see solutions where others see obstacles, and you relish the opportunity to advance cutting-edge small molecules into oral dosage forms. You are passionate about building reliable processes, ensuring regulatory compliance, and collaborating across disciplines to deliver quality drug products for clinical trials and commercial supply. If you’re seeking a pivotal role that empowers you to shape the future of pharmaceutical innovation, take the next step towards joining Novartis as the Senior Expert Science and Technology for Oral Dosage Form development About the Role As you consider taking on this influential position, here’s what you can expect from the role’s primary responsibilities. Each aspect is designed to challenge and inspire, ensuring your expertise finds its fullest expression: Oversee complex projects with significant business impact, making informed decisions from diverse data sources and actively mitigating risks to achieve project goals. Lead formulation and technical development activities for drug product manufacturing on assigned projects. Supervise development, scale-up, registration, and validation of drug substance, particle engineering, and drug development programs in accordance with Quality, HSE, and cGMP standards. Manage the manufacturing process for clinical materials, collaborating with supporting technical areas as needed. Resolve process challenges across multiple unit operations by employing both experimental methods and process simulation/modeling techniques. In this role, you will harness advanced data science and mechanistic modeling to inform every stage of development and scale-up, ensuring data-driven decisions underpin formulation strategies and process optimization. Your expertise in extracting actionable insights from complex datasets will help accelerate innovation, streamline technology transfer, and deliver robust manufacturing solutions that meet the highest standards of quality and regulatory compliance. What you’ll bring to the role: Advanced degree in a relevant scientific field, ideally in Pharmaceutical Technology. Minimum 3 years of industry experience in the development of pharmaceutical formulations for small molecules. Language English (mandatory). German or French (optional) Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary 250+ Active clinical trials are supported by Global Clinical Supply (GCS), 100k shipments are sent out annually and 1.5 million patient kits are packed. Our vision is to become an intelligent, agile organization delivering more products to more patients more efficiently through empowered and highly capable Global Clinical Supply teams! About the Role In this role you will have operational end to end responsibility for assigned activities. You will lead and manage all project and local network activities and participate in cross-functional teams. Key focus areas: •Manage End 2 End clinical supply chain for assigned projects for Clinical Finished Goods, Drug Product (Formulation), Drug Substance (API), Devices and Comparators. •Design and implement supply planning strategy is aligned with regulatory perspective •Conduct demand planning meetings for supply strategy •Participate and contribute to the TRD sub-team (project team) •Ensure discipline in SAP, Rapid Response (Kinaxis) and Operational excellence for clinical supplies Education/ experience: University degree (Science, Engineering, Business management or equivalent). Several years of work experience in Supply Chain, including experience in demand supply is a must Experience in the pharmaceutical industry and knowledge of the drug development process highly desirable You are a highly collaborative team player who enjoys working in a cross-functional matrix environment Fluency in English Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are seeking a highly motivated and experienced human geneticist. This role requires strong strategic and leadership skills, as well as expertise in genetics with a proven ability to identify the causal drivers of disease. You will be adept at leveraging these approaches within an interdisciplinary team to foster innovation and discover novel targets. As the site lead for Basel, you will have the opportunity to directly and indirectly lead a small team. This position is part of the Human Genetics & Targets group within the Discovery Sciences (DSc) department in Biomedical Research (BR) at Novartis. The DSc Human Genetics & Targets team is a global group of computational and experimental scientists dedicated to validating or invalidating genetics-driven target hypotheses. The team's extensive expertise in genetics analytics, biology, and translatable models is enhanced by DSc's capabilities in AI, functional genomics, chemical biology, and more. The team collaborates with disease area specialists to not only identify disease associations but also to understand the underlying disease mechanisms and advance drug discovery projects to benefit patients in need. About the Role Your responsibilities will include, but are not limited to: Leading a small team and working within a larger genetics computational group to plan, develop, and implement human genetic strategies for drug discovery projects in alignment with department and company goals Work with interdisciplinary project teams across a variety of disease areas to deliver (fit-for-purpose) human genetics analyses for drug discovery impact Guiding the use of population scale biobanks and serving as a champion for a human genetic cohort Coaching and mentoring the next generation of genetics experts Bringing scientific curiosity and enthusiasm to make discoveries in a collaborative and team-focused environment Engaging as an insightful and proactive member of the DSc Human Genetics Data Science team to shape the strategic direction of the team and broader BR genetics efforts What you’ll bring to the role: PhD with 7+ years of post-graduate work or equivalent experience in genetics Experience analyzing and interpreting human genetics data is a must Extensive experience with the management and analysis of large biobank data is a must and experience of multiple biobanks is preferred. Strong leadership skills and experience leading computational scientists Drug discovery experience in an industry stetting is encouraged but not required Experience with additional ‘omics data (RNA sequencing, epigenetics, proteomics) and NGS data A curiosity for emerging technologies and methods Exceptional collaboration, communication and problem-solving skills, learning agility, and an interest in engaging with peers for the design and implementation of new ideas A strong publication record Fluency in Python, R, SQL and/or other relevant programming languages Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve ​ Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The *Senior Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a Senior CDD in the Cardiovascular/Metabolic TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Main responsibilities of this role are: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred • Fluent oral and written English • Minimum 5 for CDD and 7 years experience for Snr CDD experience in clinical research or drug development • Working knowledge of the assigned disease area (Cardiovascular) is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you passionate about AI and curious how it can transform the way we discover new medicines? Join our Pharmacokinetic Sciences (PKS) Data Science team in the Translational Medicine Department for a Machine Learning Internship and explore how explainable artificial intelligence (XAI) can accelerate drug discovery. Over the course of your internship, you’ll dive into the development and validation of novel interpretation methods for AI/ML models focused on molecular property prediction and ADME/PK modeling. Working alongside experienced data scientists, medicinal chemists, and pharmacokinetics experts, you’ll help uncover actionable insights and create intuitive visualizations that make complex models more transparent. This is a unique opportunity to grow your skills in machine learning and data science while contributing to the development of life-changing therapies at Novartis. About the Role Location: Basel, Switzerland, #LI-Hybrid This internship is limited to 6 months, with the opportunity to start as soon as possible. Please note that we can only accept applicants who are eligible to work in Switzerland. Key Responsibilities: Implement novel interpretation methods to explain AI/ML predictions for molecular properties and ADME/PK models Validate XAI results in collaboration with medicinal chemists and PK experts to derive actionable insights Create intuitive visualizations of XAI outputs for scientific audiences Present project outcomes to technical and non-technical audiences Disseminate findings through publications and presentations Essential Requirements: MSc in a quantitative field or life sciences, preferably with multidisciplinary background (cheminformatics, bioinformatics, biomedical data science) Strong understanding of statistics and experience with machine learning / deep learning Expert knowledge of Python Experience with reproducible data science tools and practices Excellent communication skills and ability to translate analytical concepts for diverse audiences (English is our primary language) Desired Requirements: Previous research experience either in academia or industry Experience in explainable AI and uncertainty quantification Knowledge of ADME/PK modeling and pharmaceutical data science Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, color, race, sexual orientation, nationality or disability. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Application deadline: November 24 EOB. Please submit a cover letter that includes your motivation for the position and from when you will be available. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, Onsite, #LI-Onsite This position at Novartis in Basel seeks a Research Scientist I to join the Radioligand Therapy (RLT) team, focusing on in vivo oncology research, including animal studies and pre-clinical imaging. Candidates should have a master’s degree in a relevant field, hands-on experience with animal models and radioactive sources, and strong collaboration skills. About the Role Novartis' Biomedical Research division is our Innovation engine. We have bold objectives to transform the lives of millions of people living with diseases and conditions and unmet medical needs. Applications are invited for a Research Scientist I to carry out cutting-edge oncology drug discovery pharmacology research. We seek an experienced, motivated and ambitious individual with a passion for in vivo oncology research. You will join the Radioligand Therapy (RLT) team to develop and validate novel targets in our world leading Oncology portfolio. The position is based in Basel, Switzerland. The ideal candidate should have a passion for working with rodents and a drive to perform in vivo oncology pharmacology studies including, model development, compound administration and trained in working with open radioactive sources. Hands-on background performing small animal imaging modalities such as PET/SPECT/uCT or in cell biology techniques is a plus. The successful candidate will work collaboratively as an integral part of global projects and be an active member of lab and project teams. Responsibilities include but are not limited to: • Develop and characterize novel in vivo oncology models • Perform efficacy studies with cutting edge radioligand therapies • Perform biodistribution studies and metabolites analysis • Perform pre-clinical imaging studies including PET/SPECT/uCT • Perform and/or support colleagues with various in vitro and ex vivo activities (e.g. cell culture, flow cytometry, IHC, immunofluorescence, PCR, Western blotting) What you will bring to the role: • Masters degree in pharmacology, cell biology, medical physics, bioengineering, biotechnology or related field. Please note that for this position we do not require a PhD qualified candidate at this time. • Practical work experience in biomedical research from an industry or academic laboratory • Experience in performing animal studies (animal handling, drug application, sampling, animal welfare regulations) • Experience in working with open radioactive sources • Self-motivated, proactive, and able to work independently Desirable requirements • Knowledge and experience of standard cell biology techniques is desirable: cell culture, IHC, immunofluorescence, flow cytometry, quantitative real-time PCR, transfection, western blotting, etc., • Highly collaborative team player that enjoys working across multi-disciplinary teams • Excellent organizational and communication skills • Knowledge of cancer biology Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Welcome to where we thrive together! Are you ready to join a community where you can make a real impact on the world by supporting the global pipeline of the Immunology TA across all phases of development? At Novartis, we believe in creating a positive and inclusive work environment where we can solve the toughest healthcare challenges together. About the Role Location: Basel, Switzerland or London, UK This hybrid role can be based in Basel, Switzerland or in London, UK Key responsibilities: Defines team goals, or provides matrix leadership, aligns and provides input to department strategy to project team or company initiative. Assumes responsibility for project or initiative results, and builds a clear connection to department and company goals. Successfully leads or operationalizes key scientific/technical/development areas from the discipline to advance department and company goals. Leads PKS sub-team(s) to generate, analyze, integrate data. Works with teams to identify potential project hurdles and identifies mitigation plan (eg, resource needs, strategic alignment). Champions and advances new science relevant for project/department goals. Completes all required organizational trainings and requirements according to corporate timelines. Adhere in strict accord to the appropriate SOP and GxP guidelines. May develop and lead innovative interdisciplinary team, and/or leads through matris using a well-developed internal and external scientific network. Generates innovative strategy input and project concepts across multiple scientific/technical/development domains. Links scientific strategy with specific objectives in novel areas through flexible matrix communities and/or direct team leadership and empowerment. Conducts long-and mid-term planning to identify specific, measurable impact on team objectives. Skilled in collaboration across PKS-internal or external business partners. Utilizes established networks and builds new network connections to bring new knowledge into the department/TM/NIBR/GDD. Essential Requirements : PhD / Pharm.D. level scientist with relevant experience in drug metabolism and pharmacokinetics or related biologic background. Relevant TA/DA experience and demonstrated track record on coaching and mentoring of associates would be preferred 5+ years of experience in drug development functions (e.g. DMPK, Clinical Pharmacology) with a minimum of 5 years’ experience within a relevant LF in industry, academia or regulatory agency Extensive and in-depth knowledge of drug metabolism and pharmacokinetics including pharmacology PK and PK/PD evaluation, immunogenicity assessments and regulatory requirements. Demonstrated success leading and influencing in a multi-disciplinary environment including global project teams. Aware of the most recent developments in drug development sciences and the implications for current projects. Strong coaching, mentoring and people management skills Desirable Requirements: Proven record as team player/leader with excellent influencing & negotiation skills. Excellent organizational and project skills Commitment to Diversity and Inclusion / EEO paragraph: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and Accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10063902 Oct 21, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #Li-onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. As an In-vivo Research Scientist in the Immunology Disease Unit in Biomedical Research, you will play a pivotal role contributing to and being responsible for conducting a variety of complex research activities under the guidance of the lab head to help achieve the objectives of the immunology program. About the Role Key responsibilities of the role will include designing, overseeing, and conducting in vivo studies in rodents focused on autoimmune diseases or mechanistic PK/PD models. This involves tasks such as dosing, monitoring, scoring, and collecting samples. In addition, key responsibilities include performing ex vivo readouts such as cytokine and biomarker profiling, flow cytometry and histological evaluations to complement in vivo findings. The Research Scientist also analyzes experimental data, interprets findings, proposes innovative strategies to advance research, and maintains meticulous experimental records. Additionally, you will be responsible for prioritising tasks effectively, meeting project deadlines, and ensuring compliance with safety protocols and regulatory standards. Minimum Requirements: What you will bring to the role Your Profile: · Completed apprenticeship as a laboratory technician or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field · Minimum 2-3 years relevant lab based work experience in an industrial or academic setting,preferably in immunology research with in-vivo research as a focus LTK I or equivalent animal research qualification is essential. Research Techniques and Expertise: Proficiency in mouse models and handling techniques, including blood sampling, oral gavage, injections (IV/IP/ID/SC), perfusion, organ harvesting, anesthesia, and euthanasia Proficiency with planning and running mechanistic PK/PD in vivo models and / or disease models related to immune indications Proficiency in cellular immunology methods and ex vivo readouts such as ELISA, multiplex assays. Multicolour flow cytometry and qPCR experience would be an advantage Experience working with human cell transfer (PBMCs) and humanised mouse models is of advantage Analytical and Organizational Skills: Maintains experimental records and prepares reports aligned with study objectives and compliance guidelines Demonstrates strong planning and organizational skills, including prioritizing tasks, allocating resources, and meeting deadlines Eager to learn and combine new techniques and concepts, to present results within the lab and project teams, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Adapts quickly to new concepts and applies insights to drive innovative research solutions Excellent oral and written English *Restrictions on flexible working arrangements may apply and will be discussed at interview if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Novartis has embraced a bold strategy to drive a company-wide digital transformation. Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that foster innovative approaches to hasten drug discovery and development. By utilizing both internal and external R&D data with the power of data science, predictive models, generative AI, and machine learning, our objective is to identify new targets, create more effective therapeutic molecules, better predict drug pharmacokinetics and safety risks, refine clinical trial design, and significantly shorten development cycles. The Artificial Intelligence and Computational Sciences (AICS) team leads Biomedical Research (BR) in exploring and applying advanced AI and ML methodologies to generate novel drug discovery insights, and to speed and improve drug discovery efficiency whilst focusing on patients’ needs. AICS partners with drug discovery teams, raises the level of AI expertise across BR and ensures that BR science keeps up with the rapidly evolving ecosystem of AI technologies by connecting with AI leaders in academia and industry. This role supports the work to create and deploy Agentic Systems throughout BR in collaboration with the AICS and RX teams, BRs data science community and key stakeholders. About the Role Responsibilities: Agentic Systems: Build, implement, and deploy a cutting-edge and impactful portfolio of Agentic applications with BR drug discovery project teams and drug discovery platforms Raise the level of Agentic expertise & capabilities across BR Help position AI-aided drug discovery contributions to deliver and support progress of BR’s portfolio, enable new kinds of therapeutic discoveries, shorten cycle times, and increase efficiency. Collaboration & partnership Regularly communicate, engage, align with AICS teams, the broader data science community, and senior scientists. Initiate and lead key high-value internal collaborations across BR. Help to identify, recommend, and evaluate opportunities for Agentic collaborations across BR · Provide subject matter expertise, input, and evangelism to the field of AI across BR. What you’ll bring to the role: 4+ years of significant experience in innovation, development, deployment and continuous support of Machine Learning tools and models, including experience in an enterprise environment. 2+ years of hands-on experience fine-tuning and prompting large language models (SFT, LoRA, RLHF, ORPO, GRPO, etc.). Experience with pretraining and post-training a plus. 2+ year of hands-on experience and knowledge of retrieval-augmented generation (RAG), tool-use agents (e.g. e34wReAct style systems), and orchestration frameworks (e.g. LangChain, LangGraph, CrewAI, etc.). Strong understanding and experience using version control systems for developing software (e.g. GitHub, git, subversion, bitbucket, etc.). Proficiency in Python and experienced with automated testing, code review, and infrastructure-as-code (Terraform, CloudFormation, etc.). Entrepreneurial spirit with can-do, pro-active attitude which compliments your deep passion for understanding emerging technologies with pragmatic insight into where those technologies can be integrated into business solutions to meet stakeholder requirements. Nice to have: Expertise in bringing advanced analytics insights and actions to a large Research organization & deep understanding of Drug development. Publications, patents, or open-source contributions that demonstrate innovation agent frameworks or computational drug discovery a plus. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis has embraced a bold strategy to drive a company-wide digital transformation. Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that foster innovative approaches to hasten drug discovery and development. By utilizing both internal and external Research & Development data with the power of data science, predictive models, generative AI, and machine learning, our objective is to identify new targets, create more effective therapeutic molecules, better predict drug pharmacokinetics and safety risks, refine clinical trial design, and significantly shorten development cycles. The Artificial Intelligence & Computational Sciences (AICS) team leads Biomedical Research (BR) in exploring and applying advanced AI and ML methodologies to generate novel drug discovery insights, and to speed and improve drug discovery efficiency whilst focusing on patients’ needs. AICS partners with drug discovery teams, raises the level of AI expertise across BR and ensures that BR science keeps up with the rapidly evolving ecosystem of AI technologies by connecting with AI leaders in academia and industry. This rolewithintheAI Methodsgroup of AICS will be tasked with critical assessment of the model landscape, identifying opportunities for methodological innovation, and building the right AI approaches, algorithms, models and workflows to maximize impact on key domains areas of biomedical research that will potentially lead to developing better drugs, faster. About the Role Responsibilities: Work with a team of AI researchers, data scientists and SMEs with core domain expertise to develop and deliver focused, robust, performant AI algorithms and solutions to accelerate drug discovery. Stay informed about the latest AI methods, increase understanding of the problem domain, and ask detailed questions to identify potential areas for innovation in AI across the drug discovery pipeline. Promote awareness of advancements in AI methods for addressing key research questions within biomedical research. Fluently adopt Engineering and Product Development resources to ensure the adoption of AI solutions . Help position AI-aided drug discovery contributions to deliver and support progress of BR’s portfolio, enable new kinds of therapeutic discoveries, shorten cycle times, and increase efficiency. Collaboration & partnership A respectful, team-player attitude is an absolute must. Regularly communicate, engage, align with AICS teams, broader data science community, and senior scientists. Initiate and lead key high-value internal collaborations across BR. Help design translatable metrics for AI models that will lead to tangible impact in collaboration with BR DAs and FAs. Collaborate cross-functionally to translate model outputs into actionable hypotheses and guide experimental design. What you’ll bring to the role: 4+ years of significant experience in innovation, development, deployment and continuous support of Machine Learning and modeling. Strong hands-on coding proficiency in Python and deep learning frameworks and an expertise in bringing advanced analytics insights and actions to a large r esearch organization Wide exposure to representation learning, deep generative modeling, probabilistic reasoning, and explainability approaches. with a deep passion for understanding and explaining the technical concepts underlying ML approaches. Strong understanding and experience in using version control systems for developing software (e.g. GitHub, git, subversion, bitbucket, etc.) with expertise in large-scale model training, distributed computation, and foundation model adaptation. Publications, patents, or open-source contributions that demonstrate machine learning innovation and expertise, with passion for understanding emerging technologies and how they can integrate into business solutions Ability to balance requirements, manage expectations, and drive effective results using a proactive can-do attitude towards identifying and resolving issues, as well as a proven ability to work exceptionally well within complex matrixed teams. A deep curiosity and passion for biomedical sciences driven therapeutic discovery. Nice to have: Experience with applying ML to one or more functional areas of core drug discovery like target identification, computational chemistry, protein structure modelling and design or translational medicine is a plus. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Relevant areas of desired expertise: Transformer architectures (Text, Vision, DNA/amino-acid sequences, Gene expression vectors);Long-context transformersandefficient attention mechanisms; diffusion models;flow matching;energy-based models; multimodal architectures; graph neural networks; geometric deep learning; Bayesian optimization; Reinforcement learning; Active learning; Variational Inference; Self-supervised learning; Contrastive learning; Domain adaption; Test-time adaptation Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis has embraced a bold strategy to drive a company-wide digital transformation. Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that foster innovative approaches to hasten drug discovery and development. By utilizing both internal and external Research & Development data with the power of data science, predictive models, generative AI, and machine learning, our objective is to identify new targets, create more effective therapeutic molecules, better predict drug pharmacokinetics and safety risks, refine clinical trial design, and significantly shorten development cycles. The Artificial Intelligence & Computational Sciences (AICS) team leads Biomedical Research (BR) in exploring and applying advanced AI and ML methodologies to generate novel drug discovery insights, and to speed and improve drug discovery efficiency whilst focusing on patients’ needs. AICS partners with drug discovery teams, raises the level of AI expertise across BR and ensures that BR science keeps up with the rapidly evolving ecosystem of AI technologies by connecting with AI leaders in academia and industry. This role within the Scientific Innovation group of AICS will be tasked with ensuring scientific rigor and innovation for AI applications and methods for drug discovery. Additionally, the role would be expected to act as the SME liaison of AICS to BR Disease Areas (DAs) and Function Areas (FAs). About the Role Responsibilities: Scientific Innovation Senior Expert: Work with a team of AI researchers and SMEs with core domain expertise in applying AI to drug discovery. Work with AI modelers to ensure models are robust and performant Work with Engineering and Product Development resources to ensure delivery of AI solutions. Raise the awareness of AI applications to aid in answering key research questions across BR. Help position AI-aided drug discovery contributions to deliver and support progress of BR’s portfolio, enable new kinds of therapeutic discoveries, shorten cycle times, and increase efficiency. Collaboration & partnership: Act as liaison of AICS for identification of research questions, solution design, and evangelism of results and impacts of AI across BR Regularly communicate, engage, align with AICS teams, broader data science community, and senior scientists. Initiate and lead key high-value internal collaborations across BR. Help design translatable metrics for AI models that will lead to tangible impact in collaboration with BR DAs and FAs. Essential Requirements: 4+ years of significant experience in innovation, development, deployment and continuous support of Machine Learning data management and modeling, including experience in an Enterprise environment Specialization in at least one of the core drug discovery functional areas like target identification, computational chemistry, protein structure modelling and design or translational medicine. Expertise in bringing advanced analytics insights and actions to a large Research organization & deep understanding of Drug development. Entrepreneurial spirit with can-do, pro-active attitude which compliments your passion for understanding emerging technologies with pragmatic insight into where those technologies can be integrated into business solutions. Ability to balance requirements, manage expectations, and drive effective results using a proactive attitude towards identifying and resolving issues. Strong organizational, problem-solving, and influencing skills and demonstrated track record of exceptional teamwork. Functional leadership capability with excellent interpersonal, communication, and presentation skills. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Der CBC Equipment Specialist ist verantwortlich für den GMP-konformen Herstellungsprozess von Zellbanken im Basel Cell Bank Center. Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role Major Accountabilities Teilnahme an den Herstellungsprozessen Durchführung aller notwendigen Verarbeitungsschritte des Zellbankwesens mit höchstemKenntnisstand der aseptischen/niedrigen Keimbelastungstechnik (Auftauen, Zellpassage,Zellzählung und Einfrieren der Zellbank) Ausführung sämtlich zugewiesener Tätigkeiten gemäß dem Produktionsplan und der gültigenGMP-, Arbeits-,Betriebs-, Umwelt- und Sicherheitsanweisungen und -richtlinien Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagenund -räume Verantwortung für die Haushaltsführung des Produktionsbereichs (Reinigung, Ordnung, 5S, usw.) Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien(HSE) Anwendung und Durchsetzen der aktuellen GMP-Regeln Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften Education: Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen, Technischer Abschluss; Universitatsabschluss (Chemieingenieurwesen, pharmazeutische Technologie, Biotechnologie, Biochemie) fur einige Technologieplattformen erwOnscht oder gleichwertige Erfahrung Languages: Grundkenntnisse in Englisch und Beherrschung der Landessprache des Standorts - German Experiences: Mindestens 2 Jahre abgeschlossene Berufserfahrung als Novartis-Gerätebediener oder (vorzugsweise) 5 Jahre in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you a Bachelor´s student or recent graduate eager to gain hands-on experience in corporate communications within a global organization? As a Full-Time Intern, you will support internal and external communications projects for the International President, contributing to content creation, digital channel operations, and stakeholder engagement. This internship offers a unique opportunity to build skills in a fast-paced, international environment. You will report to the Senior Manager, International President Communications and help advance the communications strategy for Novartis International—a commercial unit serving Europe, Asia, Africa, Australasia, Canada, and Latin America, which reached over 220 million patients in 2024. About the Role Location: Basel, Switzerland, #LI-Hybrid This internship is limited up to 11 months with a possible start date in January 2026. Please note that we can only accept applicants who are eligible to work in Switzerland. Key Responsibilities: Engagement & Editorial Support: Track engagement activities and maintain the editorial calendar for the International President. Content & Presentation Creation: Assist in preparing stakeholder materials, presentations, and internal briefings. Social Media & Communication Channels: Monitor and support platforms like LinkedIn and Novartis Hub, draft posts, and manage communication channels and inboxes. Event & Campaign Support: Contribute to content development for international employee events and help track campaign metrics. Multimedia & Vendor Coordination: Organize multimedia archives and assist with liaising with agencies and vendors for team projects. Essential Requirements: Currently pursuing or recently completed Bachelor´s degree in Communications, Public Relations, Marketing, or a related field. Strong interest in corporate and digital communications. Excellent organizational skills and attention to detail. Fluent in English, with solid written and verbal skills. Ability to work effectively as part of a team and follow instructions. Willingness to learn and take initiative on assigned tasks. Desirable Requirements: Familiarity with social media platforms and digital tools. Additional language skills beyond English. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, color, race, sexual orientation, nationality or disability. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Application deadline: November 21 EOB. Please submit a cover letter that includes your motivation for the position and from when you will be available. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you an enthusiastic and motivated recent graduate with a master’s degree in analytical sciences related field (e.g. biochemistry, biology, chemistry, biotechnology), and a strong background in protein biochemistry? This position is within our Biologics Analytical Development department, supporting process analytical method development and testing for biological products in clinical development for up to one year. The role offers opportunities to contribute to improvement initiatives and provide hands-on support to the teams in Process Analytical Sciences. About the Role Location: Basel, Switzerland #LI-Onsite This Postgraduate internship is limited up to 1 year with the opportunity to start in January 2026. Please note that we can only accept applicants who are eligible to work in Switzerland. Key Responsibilities: Develop and execute analytical methods for process analytical testing of biological products Evaluate modelling-based digital solutions for analytical method development Support improvement initiatives and contribute to process optimization projects. Provide hands-on support to laboratory teams as needed Essential Requirements: Master´s degree in a relevant field (e.g. biochemistry, biology, chemistry, biotechnology, etc.) with experience in protein biochemistry Hands-on laboratory experience with protein analysis Solid knowledge of protein biochemistry Good command of English (oral and written) Strong teamwork and communication skills with flexibility to take on diverse tasks Desirable Requirements: Experience with modeling-based digital solutions for laboratory applications Savviness with digital applications Interest in process improvement and continuous optimization Quick grasp and passion to learn new things Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, color, race, sexual orientation, nationality or disability. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Application deadline: November 21 EOB. Please submit a cover letter that includes your motivation for the position and from when you will be available. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Locations: This role can be based in either Basel, Switzerland, Dublin, Ireland, or Westworks, London, UK Full time Hybrid The role of Director Research & Development Strategic Insights is a pivotal role in driving high-quality, evidence-based decisions that impact Novartis’ global R&D pipeline. This role translates internal and competitive insights into actionable strategies that guide resource allocation, pipeline prioritization, and execution across our portfolio to bring the right medicines faster to patients. About the Role This role partners closely with stakeholder across units including Development and Research Program Teams, Disease Area leadership, and governance boards (Discovery & Translational Board, Development Leadership Team, Innovation Management Board) to provide an independent perspective on scientific, strategic, and operational aspects of programs in combination with insights from the external landscape and competitor activities. Beyond pipeline strategy, this role leads and/or contributes to high-impact, cross-functional initiatives aimed at enhancing R&D performance and accelerating project delivery as well as contributing to the definition of the future pipeline strategy. This is a unique opportunity to influence decisions at the highest level and ensure Novartis remains at the forefront of innovation. Key Responsibilities: Partner with R&D project teams (BPTs/GPTs) and DU/DA leadership from project start to approval to support tollgate and update preparation for strategic decisions at key governance boards and foster connection and exchange of Best Practice between BPTs and GPTs to enable drug discovery and development acceleration. Enable R&D leadership and key governance boards to make strategic decisions by bringing independent internal, external, competitor, and industry perspectives on assets, programs, and events with clear, actionable recommendations. Lead rigorous program/project feasibility assessments across key dimensions (science/preclinical, clinical, safety, regulatory, technical, clinical execution) Provide independent competitive insights and benchmarks on programs and trials and related events in assigned therapeutic area(s) and platform(s) incl implications for portfolio to the R&D organizations (leadership, teams, functions) to support project, TA and platform strategy. Work directly with project teams to help identify most relevant competitors and integrate insights into project strategies. Lead and/or support selected cross-functional, high-visibility initiatives/projects and deliver actionable insights on R&D pipeline strategy and performance (e.g., cross-portfolio reviews, peer pharma analyses, platform strategy, trial execution). Create disease area overviews and asset insights in the dedicated TA to inform mechanism-of-action strategy, competitive positioning, expansion opportunities, incl. learnings and watch-outs for the programs. Minimum Requirements Graduate life sciences degree (Master’s or equivalent) required; PhD or equivalent preferred. Additional business degree (MBA) or equivalent business experience desirable. Minimum 10+ years in the pharmaceutical/biotech industry; experience in areas of either CI/Brand Management/Analytics/Value and Access with a leading pharmaceutical/ solution provider or experience in Pharma R&D.; experience in both fields are an advantage. Track record of operational excellence and the ability to synthesize complex data into succinct, actionable insights for senior audiences and to translate analytic skill into strategy. Deep understanding of R&D and the global competitive environment as well as knowledge of assigned disease area gained through roles in respective environment Proven strong leadership in a cross-functional matrix and the ability to influence without direct authority and establish effective partnerships. Proven ability to deliver under tight timelines and with demanding stakeholders Clear, audience-tailored communication style suited for senior management; ability to develop a persuasive and credible presentation style at all levels of organization. Extensive cross-functional work experience in international multidisciplinary teams in drug development or consultancy with ideally exposure to the full R&D lifecycle Strong process/project management skills; with experience in remote relationships (on-shore / off-shore capability delivery). Fluent English (oral and written) Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Locations: Basel, Switzerland; Dublin, Ireland; Westworks, London, UK The Director, Systemic Global Program Team Coaching, serves as a strategic enabler of business performance by activating Global Program Teams (GPTs) to deliver on critical business objectives. This role partners with senior leaders and cross-functional teams to strengthen team ownership, enhance collaboration, and accelerate impactful delivery across the organization. By applying advanced systemic team coaching practices, the Director builds clarity, trust, alignment, and execution capability within teams, directly supporting transformation, cultural change, and strategic delivery. The position embeds coaching as a lever for both development and enterprise impact, with a particular focus on GPTs, and operates in high-stakes, complex environments to foster sustainable team effectiveness and organizational learning. About the Role Job Description Key Responsibilities: Lead multi-session coaching engagements tailored to internal contexts, using systemic team coaching frameworks—including preparation, facilitation, and follow-up. Support leaders in understanding their systemic role, preparing for key team moments, and fostering a healthy team climate. Help teams convert enterprise strategy into actionable objectives and execution plans, driving ownership and accountability. Guide teams in clarifying purpose, roles, ways of working, stakeholder engagement, and performance goals. Leverage data and assessments to generate actionable insights that inform team development and business decisions. Act as a catalyst for mindset and behavioral shifts using self-awareness, presence, and relational intelligence. Partner with business sponsors and functional leaders to ensure coaching efforts support market demands and performance goals. Empower teams to internalize coaching practices and operate autonomously, reducing long-term reliance on the coach. Essential Requirements: Bachelor’s degree in a relevant discipline is required. Proven experience working within the pharmaceutical industry, ideally in a drug development or R&D setting Familiarity with the dynamics of cross-functional teams in regulated environments, including exposure to clinical development, program execution, or lifecycle management of medicines. Possesses or is actively working toward advanced coaching accreditation (e.g., CPCC, ICF, PCC/MCC, ACTC), with a strong commitment to maintaining ongoing professional certification. Strong commitment to ethical practice, supervision, and ongoing self-development (e.g., certifications in ORSC - Organization & Relationships System Coaching, NTL-National Training Laboratory, NLP-Neurolinguistic Programming, Shadow Walk, Gestalt, Systemic Team Coaching, Immunity to Change approach, etc.), aligned with ICF standards, modeling the principle that the coach is an instrument of transformation. Commitment to abide by the ICF Code of Ethics and uphold the Core Values. Deep experience in team coaching, leadership development, and systems thinking. Demonstrated success in partnering with senior leaders in complex, matrixed environments to support cross-functional collaboration, while influencing organizational culture. Knowledge of behavioral science and neuroscience-informed coaching. Proven track record in high-change, high-uncertainty environments, delivering meaningful results in a “team of teams” and multi-level organizational contexts. History of delivering team coaching results in a myriad of delivery methods: face-to-face, virtual and hybrid environments. Ability to understand the contextual awareness of the business, without being embedded in the team or aligned to its delivery or performance. Fluent oral and written English Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Our ambition is to be leaders in immunology across international markets. The Executive Director International, plays a pivotal role in leading the end-to-end Rheumatology strategy for the brand, encompassing the vision, development, orchestration, implementation, and evaluation of integrated strategies across major international markets. As an enterprise leader, the ED will focus on the top three countries (Germany, Japan, and China) and Regions, driving successful launch and growth across its indications. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, and Customer & Market Activation teams to drive consistent strategy development and execution. This role represents the commercial team across different instances of the organization. About the Role Key Responsibilities International Launch Strategy: Lead the development and implementation of the launch plan for the assigned indication, ensuring alignment with overall asset strategy and corporate objectives. Cross-Functional Leadership: Orchestrate a global/international, cross-functional team (Medical, Regulatory, Access, Commercial, Supply, etc.) to deliver seamless launch execution. Launch Readiness: Assess and drive readiness across core and priority markets, identifying risks and enabling mitigation plans to ensure timely launch execution. Insight Integration: Leverage market research, competitive intelligence, and stakeholder feedback to refine positioning, messaging, and tactical planning. International-Local Partnership: Partner closely with regional and country teams to ensure pull-through of global strategy, providing guidance and tools to support in-market success. Milestone Tracking & Governance: Define and track critical launch milestones and KPIs; lead governance updates and ensure timely decision-making across key forums. Stakeholder Engagement: Effectively communicate our vision and strategic goals to senior leaders, including the International Leadership Team (ILT), Country Presidents (CP), and regional heads. Compliance & Excellence: Uphold the highest standards of compliance and launch excellence throughout all activities. Collaborate closely with global development to influence target product profile & Integrated Evidence Plan to maximize commercialization & patient access potential for the new indications and LCM in key markets in international. Lead the International Commercialization Excellence (ICE) initiatives, driving best practices in customer engagement strategies. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Essential requirements: +15 years of commercial experience across various functions in country(s) and above country, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful launches, with commercial leadership experience and therapeutic area (TA) leadership in core markets. Extensive commercial experience in immunology, especially working with rheumatologists. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches. Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM). Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leadership Capabilities: Proven ability to manage and drive performance, ensuring targets are met and exceeded in challenging markets. Demonstrated ability to lead and inspire teams, drive cross-functional collaboration, and think strategically in dynamic environments. Focuses on larger, longer-term issues, and creates plans and strategies. Comfortable in navigating the matrix and people related organizational dynamics. Establish credibility & influence across diverse stakeholders and able to navigate in an environment of shared outcomes and cross-business accountabilities. Demonstrates enterprise leadership, balance diverse stakeholders and conflicting priorities to drive results. Empowered teams to execute efficiently, through the layers of organization and across geographies. Clearly and effectively communicates with senior stakeholders (both internal &external)– to align on vision, purpose & goals. Generates trust, builds credibility and drives engagement with people and stakeholders. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland or Cambridge, MASS, US. Full time, hybrid #LI-Onsite The Oncology Data Science (OncDS) team in Biomedical Research provides computational biology, AI, and data expertise and brings together projects spanning the entire pre-clinical to clinical development pipeline across a wide and unique range of novel therapeutics. OncDS specializes in using high-throughput genomic and biomarker data for target identification, drug discovery, and clinical development. We are seeking an enthusiastic Senior Computational Scientist / Data Engineer that can combine data science tools with biological knowledge to perform exploratory data analyses, curate high-quality datasets, build efficient data workflows, and apply automation and AI to ensure accuracy and scalability in our data systems. Join a team that values curiosity, collaboration, innovation, and growth, and make a meaningful impact at the intersection between cutting-edge science and technology. About the Role Key responsibilities: Collaborate with cross-functional teams to curate key experimental and omics datasets with an emphasis on quality and correctness to ensure that our complex scientific data are trustworthy Perform exploratory data analyses on key experimental and omics datasets Evaluate and implement automation tools and AI/ML approaches to enhance data curation and EDA workflows that increase the speed and accuracy of data handling Collaborate with cross-functional teams to develop and adopt best practices for data engineering Essential Requirements: Ideally an advanced degree (PhD, MS, or BS) in Computational Biology, Bioinformatics, Data Science, Computer Science, or related field with relevant experience A minimum of 5-8 years in either academia or industry working in an equivalent position in computational biology, bioinformatics, data engineering, or related field At least 4-5 years of experience working with molecular biology or omics data Demonstrated statistical and analytic rigor while performing exploratory data analyses and drawing scientific conclusions from experimental data (e.g., scRNAseq, RNAseq, ChIPseq, DNAseq, proteomics, compound screens, or CRISPR screens) Fluent in one or more programming languages with bioinformatics applications (R, Python) Knowledge of version control, reproducible workflows, Unix / Linux Curiosity, creativity, strong organizational skills, solution-oriented problem solving Ability to work independently, prioritize tasks, determine project next steps, manage multiple projects and stakeholders simultaneously Excellent written and verbal communication skills, including the ability to explain complex concepts to diverse audiences Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10064626 Oct 28, 2025 Switzerland Summary Location: Basel, Switzerland or Cambridge, MASS, US. Full time, hybrid #LI-Onsite The Oncology Data Science (OncDS) team in Biomedical Research provides computational biology, AI, and data expertise and brings together projects spanning the entire pre-clinical to clinical development pipeline across a wide and unique range of novel therapeutics. OncDS specializes in using high-throughput genomic and biomarker data for target identification, drug discovery, and clinical development. We are seeking an enthusiastic Senior Computational Scientist / Data Engineer that can combine data science tools with biological knowledge to perform exploratory data analyses, curate high-quality datasets, build efficient data workflows, and apply automation and AI to ensure accuracy and scalability in our data systems. Join a team that values curiosity, collaboration, innovation, and growth, and make a meaningful impact at the intersection between cutting-edge science and technology. About the Role Key responsibilities: Collaborate with cross-functional teams to curate key experimental and omics datasets with an emphasis on quality and correctness to ensure that our complex scientific data are trustworthy Perform exploratory data analyses on key experimental and omics datasets Evaluate and implement automation tools and AI/ML approaches to enhance data curation and EDA workflows that increase the speed and accuracy of data handling Collaborate with cross-functional teams to develop and adopt best practices for data engineering Essential Requirements: Ideally an advanced degree (PhD, MS, or BS) in Computational Biology, Bioinformatics, Data Science, Computer Science, or related field with relevant experience A minimum of 5-8 years in either academia or industry working in an equivalent position in computational biology, bioinformatics, data engineering, or related field At least 4-5 years of experience working with molecular biology or omics data Demonstrated statistical and analytic rigor while performing exploratory data analyses and drawing scientific conclusions from experimental data (e.g., scRNAseq, RNAseq, ChIPseq, DNAseq, proteomics, compound screens, or CRISPR screens) Fluent in one or more programming languages with bioinformatics applications (R, Python) Knowledge of version control, reproducible workflows, Unix / Linux Curiosity, creativity, strong organizational skills, solution-oriented problem solving Ability to work independently, prioritize tasks, determine project next steps, manage multiple projects and stakeholders simultaneously Excellent written and verbal communication skills, including the ability to explain complex concepts to diverse audiences Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Cambridge (USA), Massachusetts, USA Functional Area Data and Digital Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Join a dynamic team where you will be managing high-impact patent litigation cases. You'll work closely with both in-house and external counsel, driving strategic litigation efforts and overseeing key operational processes. This role offers the opportunity to lead projects that enhance litigation workflows, contribute to budget planning, and deliver insightful IP reporting—making a real difference in how we protect and leverage our intellectual property. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities : Provides and utilizes IP expertise to support several IP Counsels and the IP function as a whole - championing quality, collaboration and operational excellence in the Department. Contributes to the implementation and application of IP policies and guidelines - providing non-legal advice to business colleagues, collaborating with the business under the supervision of project leads to ensure business goals are met in an efficient and timely manner. Contributes to the #OneNovartisIP culture - Proactively and autonomously supports in-house patent litigation counsel and attorneys in preparation for patent enforcement and defense, by interacting with local counsel and local Business Franchises. Maintain and share advanced knowledge of latest litigation rules and adapting practices to comply. Monitor and updating Anaqua on a daily basis. Communicate effectively with colleagues, agents and other associates - Actively participate in litigation group and cross-divisional meetings as needed – being flexible to provide support in other areas within the Patent Support team (i.e. invoicing and data input). Leads teams in development of procedures and processes - ability to conduct meetings as needed; Recommends areas/systems of possible improvement in efficiencies in procedures. Leads projects relating to litigation processes/operations, driving the successful implementation of new and revised processes and guidelines. Autonomously supports in-house patent litigation counsel and attorneys on matters such as patent ownership and licensing structure. Manages the flow of information by acting as a contact point for local lawyers/local team for patent litigation matters – using Litigation database document and information management; familiarity with patent databases e.g. PatBase, Espacenet, etc. Attend and draft memorandum of litigation meetings with local counsel and local business, provide action points and follow up on agreed objectives. Manages the IP Litigation budget process; drive the preparation of and deliver the various litigation budget forecasts by liaising with internal and external attorneys & counsel, as well as BPA, assisting in the review, as appropriate. Responsible for full project life cycle including Liaises with department eBilling coordinator, utilizes Anaqua to record and report litigation matters, litigation reporting and leads the interactions on behalf of IP Litigation Project Team with any third-party co-owners, licensors, patentees. Supervision of junior litigation paralegals, local litigation team coordinators and new team members providing guidance on internal and external processes, litigation database management, etc. Essential Requirements: Relevant degree, or equivalent experience. Paralegal qualification/ certifications or equivalent Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as an IP paralegal or equivalent in an IP litigation law firm or corporation. Extensive experience in autonomously providing complex patent litigation support in a large multinational company preferably in-house, or in a law firm. Able to work autonomously in preparation of draft schedules and supporting documents for subsequent attorney review - able to communicate with business clients in multiple countries. Excellent team-player with exemplary interpersonal skills - Reliable, service-oriented with impeccable integrity and willingness to learn. Proven ability to balance and identify priorities in daily work, manage varying workload levels, ensuring a consistent work product, and support the IP team efficiently and in a solution-oriented, contextualized manner. Proactive approach to project/workstream involvement. Able to consider the needs of the team and where they can contribute, implementing or suggesting solutions prior to being instructed. Active participation in relevant projects - willingness to learn and develop in role. Extensive experience in autonomously managing complex patent litigation support in a large multinational company, preferably in-house, or in a law firm. IP Identified leadership potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060551 Sep 16, 2025 Switzerland Summary To provide strategic, medical and scientific guidance and leadership for the development of multiple experimental agents in the Translational Clinical Oncology (TCO) portfolio beginning with input to early Target identification and continuing through to the Transition Decision Point. Formulate actionable development plans with the Development Organization to ensure rapid and seamless decision making and transitions of portfolio molecules and other assets. Provide scientific and clinical leadership to inform potential external innovative programs and business development in strategic areas of focus for the company. About the Role Key Responsibilities: Serve as an Early Clinical Development Area Leader for TCO, overseeing and implementing innovative clinical strategies for multiple molecules/assets that are advancing clinical testing in strategic indications, ensuring that robust and comprehensive development plans are in place and implemented. Oversee physicians (including direct reports and others) with strong mentorship and attention to ensure the strategic and operational aspects of their programs align with the overall oncology strategy and to foster their career development. Represent TCO programs and program strategy at governance boards in BR (e.g., TCO-Leadership Team (LT), Integrated Cancer Decision Board (ICDB), Discovery & Translational Board (DTB) and across the organization (e.g., Oncology Development Unit (ODU-LT), Therapeutic Area Leadership Team (TAL). Provide senior leadership and clinical input to clinical studies and pre-clinical research projects under their responsibility, effectively integrating their medical knowledge with expertise of colleagues in a wide range of other disciplines (e.g., Clinical Pharmacology, Biostatistics) to optimize the clinical development strategy, including supporting subsequent registration trials. Critically review and provide constructive feedback on documents for programs and studies under supervision including but not limited to protocol, Investigators Brochures (IBs), and health authority responses. Provide strategic input on internal and external assets and portfolio areas, representing TCO in Business Development and Licensing due diligence reviews and integrations. Lead or help oversee external collaborations, partnering closely with colleagues across the company. Play leadership roles in early development committees and initiatives by actively contributing strategic advice (e.g., the Study Concept Review Board and Protocol Review Committee). Apply medical knowledge to guide the safe, ethical and efficient conduct of own trials. Strive to maintain or exceed compliance obligations for Good Clinical Practice guidelines and Novartis Standard Operating Procedures. Liaise with outside experts, investigators, and regulatory authorities in oncology early clinical development First in Human (FIH) trials and represent projects to those groups and authorities. Write and review abstracts/manuscripts for presentation/publications at internal/external meetings. Mentor and serve as an educational resource and expert within Biomedical Research (BR) and across the organization. Essential Requirements: This hybrid position will be located at the Basel campus. This position will require 20-25% travel as defined by the business (domestic and/ or international). MD degree and PhD-level basic science required (PhD not required). MD / PhD preferred. Board-certification (or equivalent expertise) in Hematology-Oncology (heme-onc). Minimum 7 years- experience leading complex global early phase hematology-oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. In case of no industry experience, substantially longer academic experience in translational hematology/oncology and substantial clinical study experience. Recognized as a Heme-Onc expert with a substantial record of quality scientific publications and international recognition for expertise. Interpretation of preclinical data in hematology/oncology (molecular biology, pharmacology, pharmacokinetics, and toxicology). Working knowledge of the application of PharmacoKinetics (PK) / PharmacoDynamics (PD) and biostatistics to clinical development and trials. Proven ability to analyze and interpret efficacy and safety data relating to oncology. Knowledge of Good Clinical Practices (GCP) and world-wide regulatory requirements relating to clinical trials and oncology. Excellent medical/scientific writing and oral communication/presentation skills. Proven ability to manage and develop a team. Outstanding scientific mentor; inspires others. Excellent personal ethical integrity and commitment to improving outcomes for patients with malignancies. #LI-hybrid Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture&nbsp ; You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We are seeking a highly motivated Associate Director of Biostatistics; you will be required to influence and drive the statistical strategy and innovation through strong collaborations and decision making for assigned trials/programs within (early/full) clinical development and/or medical affairs. Proven experience in execution and analysis of complex clinical trials and leading strategy through collaborations with partners across the organization. About the Role Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people’s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic areas and platform depth and capabilities – all to bring our medicines to patients even faster. We are seeking key talents, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and welcome to where we thrive together! The Role: We are seeking a highly motivated Associate Director of Biostatistics; you will be required to influence and drive the statistical strategy and innovation through strong collaborations and decision making for assigned trials/programs within (early/full) clinical development and/or medical affairs. Proven experience in designing, and analyzing complex clinical trials and leading strategies through collaborations with partners across the organization and depending on the role, supporting regulatory submissions including planning, analysis and reporting of clinical safety and efficacy summaries as well as interacting with Health Authorities. Representing the Advanced Quantitative Sciences function both internally and externally on decision boards, developing and mentoring other statisticians, and providing solutions to the organization. This role may be in Early Development, Full Development (Oncology, Immunology, Cardio-Renal Metabolic or Neuroscience) Global Medical Affairs Key requirements: Responsible for all statistical tasks on assigned clinical trials and perform these tasks for high complexity trials with a high level of independence seeking peer input/review as required. Responsible for protocol development in alignment with the development plan, developing statistical analysis plan, and reporting activities. Contribute to planning and execution of exploratory analyses, innovative analyses related to publications and pricing & reimbursement submission and/or PK, PK/PD analyses, exploratory biomarker and diagnostic analyses, and statistical consultation. Initiate, drive, and implement novel methods and innovative trial designs and dose-finding strategies in alignment with the Lead Statistician. Experience in providing statistical expertise to support submission activities, including documents, meetings with and responses to Health Authorities, pricing agencies and drug development activities, as required. Independently lead interactions with external review boards/ethics committees, external consultants, and other external parties with oversight as appropriate. Represent Novartis in statistical discussions at external congresses, conferences, scientific meetings. Represent the Advanced Quantitative Sciences Line Function on cross-functional teams for the assigned trials. Responsible for functional alignment and ensuring line function awareness throughout the trials. Collaborate with other line functions. Explain statistical concepts in an easily understandable way to non-statisticians and provide adequate statistical justifications and interpretation of analysis results for actions/decisions/statements, when required. Establish and maintain sound working relationships and effective communication within the clinical trial team and the Advanced Quantitative Sciences team. Independent oversight of Biostatistics resources and deliverables for assigned trials. Ensure timeliness and adequate quality of all Biostatistics deliverables for the assigned trials and/or non-clinical related activities. Your Experience: MS Statistics with work experience or PhD (in Statistics or equivalent) with work experience Fluent in English with strong communication and presentation skills, with the ability to articulate complex concepts to diverse audiences. Effective utilization of innovative statistics and quantitative analytics to influence assigned program team decisions and support department to deliver objectives. Proven knowledge and expertise in statistics and its application to clinical trials. Depending on the assignment, it may require proven expertise in pharmacokinetics, exposure-response modelling, exploratory biomarker, diagnostic analyses, applied Bayesian statistics, or data exploration skills. Demonstrated excellence in use of statistical software packages (e.g. SAS, R). Strong knowledge of drug development and Health Authority guidelines. Experience in independently leading a multidisciplinary team to achieve team objectives. Expert skills to facilitate and maximize the contribution of quantitative team. Hands-on experience in leading the interface to regulatory agencies/leading the early clinical development campaign. Strong understanding of Development Unit /Therapeutic Area and or regulatory activities(depending on the role: Oncology, Immunology and Cardio Renal Metabolic) and or regulatory activities. Expert scientific leadership skills demonstrated in facilitating and optimizing the (pre/early/full-) clinical development strategy. Strong track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies. Demonstrated strong skills in building partnerships and collaborations. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10062884 Oct 02, 2025 Switzerland Summary We are seeking a highly motivated Associate Director of Biostatistics; you will be required to influence and drive the statistical strategy and innovation through strong collaborations and decision making for assigned trials/programs within (early/full) clinical development and/or medical affairs. Proven experience in execution and analysis of complex clinical trials and leading strategy through collaborations with partners across the organization. About the Role Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people-s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic areas and platform depth and capabilities - all to bring our medicines to patients even faster. We are seeking key talents, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and welcome to where we thrive together! The Role: We are seeking a highly motivated Associate Director of Biostatistics; you will be required to influence and drive the statistical strategy and innovation through strong collaborations and decision making for assigned trials/programs within (early/full) clinical development and/or medical affairs. Proven experience in designing, and analyzing complex clinical trials and leading strategies through collaborations with partners across the organization and depending on the role, supporting regulatory submissions including planning, analysis and reporting of clinical safety and efficacy summaries as well as interacting with Health Authorities. Representing the Advanced Quantitative Sciences function both internally and externally on decision boards, developing and mentoring other statisticians, and providing solutions to the organization. This role may be in Early Development, Full Development (Oncology, Immunology, Cardio-Renal Metabolic or Neuroscience) Global Medical Affairs Key requirements: Responsible for all statistical tasks on assigned clinical trials and perform these tasks for high complexity trials with a high level of independence seeking peer input/review as required. Responsible for protocol development in alignment with the development plan, developing statistical analysis plan, and reporting activities. Contribute to planning and execution of exploratory analyses, innovative analyses related to publications and pricing & reimbursement submission and/or PK, PK/PD analyses, exploratory biomarker and diagnostic analyses, and statistical consultation. Initiate, drive, and implement novel methods and innovative trial designs and dose-finding strategies in alignment with the Lead Statistician. Experience in providing statistical expertise to support submission activities, including documents, meetings with and responses to Health Authorities, pricing agencies and drug development activities, as required. Independently lead interactions with external review boards/ethics committees, external consultants, and other external parties with oversight as appropriate. Represent Novartis in statistical discussions at external congresses, conferences, scientific meetings. Represent the Advanced Quantitative Sciences Line Function on cross-functional teams for the assigned trials. Responsible for functional alignment and ensuring line function awareness throughout the trials. Collaborate with other line functions. Explain statistical concepts in an easily understandable way to non-statisticians and provide adequate statistical justifications and interpretation of analysis results for actions/decisions/statements, when required. Establish and maintain sound working relationships and effective communication within the clinical trial team and the Advanced Quantitative Sciences team. Independent oversight of Biostatistics resources and deliverables for assigned trials. Ensure timeliness and adequate quality of all Biostatistics deliverables for the assigned trials and/or non-clinical related activities. Your Experience: MS Statistics with work experience or PhD (in Statistics or equivalent) with work experience Fluent in English with strong communication and presentation skills, with the ability to articulate complex concepts to diverse audiences. Effective utilization of innovative statistics and quantitative analytics to influence assigned program team decisions and support department to deliver objectives. Proven knowledge and expertise in statistics and its application to clinical trials. Depending on the assignment, it may require proven expertise in pharmacokinetics, exposure-response modelling, exploratory biomarker, diagnostic analyses, applied Bayesian statistics, or data exploration skills. Demonstrated excellence in use of statistical software packages (e.g. SAS, R). Strong knowledge of drug development and Health Authority guidelines. Experience in independently leading a multidisciplinary team to achieve team objectives. Expert skills to facilitate and maximize the contribution of quantitative team. Hands-on experience in leading the interface to regulatory agencies/leading the early clinical development campaign. Strong understanding of Development Unit /Therapeutic Area and or regulatory activities(depending on the role: Oncology, Immunology and Cardio Renal Metabolic) and or regulatory activities. Expert scientific leadership skills demonstrated in facilitating and optimizing the (pre/early/full-) clinical development strategy. Strong track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies. Demonstrated strong skills in building partnerships and collaborations. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Are you looking for a new challenge? A role where you can drive change, make impact - an opportunity to develop & shape a new pilot plant? You will be able to do just that as our Global Aseptic Network Lead by being accountable for establishing, leading, and continuously developing the TRD QA Sterile Operations Network. This will ensure phase-appropriate, best-in-class sterile standards, knowledge sharing, and cross-functional collaboration that drive quality, compliance, and innovation across all modalities. About the Role Establish, lead, and continuously develop the TRD QA Sterile Operations Network, fostering accountability, learning, and collaboration. Provide specialist knowledge and guidance on sterile and low bioburden processes, ensuring compliance with regulatory requirements. Implement, harmonize, and continuously improve aseptic standards and best practices across TRD pilot plants and all modalities (Cell and Gene Therapies, Radioligand Therapies, ADC, and New Biological Entities). Drive continuous improvement, knowledge transfer, and innovation in sterility assurance. Act as a key partner in cross-functional projects, troubleshooting issues and aligning stakeholders on pragmatic solutions and standards. Mentor and develop members of the TRD QA Sterile Operations Network, addressing critical skills gaps. Consult on the evaluation and selection of external contractors for aseptic appropriateness, ensuring integrity of outsourced processes. Desired skills: Influence without authority in a matrix environment—build credibility, align stakeholders, and drive standards adoption. Proactive relationship-building—actively engage cross-functional partners to create momentum for change. Pragmatic risk-taking—balance diligence with smart, solution-oriented decision-making. Advanced problem-solving—lead troubleshooting and resolution across departmental boundaries. Effective communication—tailor messaging, negotiate, and handle pushback diplomatically. Political savvy—navigate informal networks and overcome barriers to secure a seat at the table. Qualifications Advanced degree (PhD, MSc, or equivalent) in life sciences, pharmacy, or related field Extensive experience in sterile manufacturing, quality assurance, or related areas within the pharmaceutical/biotech industry Strong knowledge of aseptic processing, sterility assurance, and regulatory requirements (e.g., FDA, EMA, ICH) Proven track record in leading cross-functional teams or networks, ideally in a matrix environment Demonstrated ability to influence without authority and drive change across organizational boundaries Excellent problem-solving, communication, and stakeholder management skills Fluent in English; additional languages a plus Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a CDD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements: • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred • Fluent oral and written English • Minimum 7 years experience in clinical research or drug development • Working knowledge of the assigned disease area is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: The Compound Management & Engineering (CME) unit is responsible for maintaining, expanding, and distributing the compound collection used in global drug discovery projects. To support rapid and reliable delivery of thousands of stock solutions across the research community, CME relies on complex robotic systems. We are currently seeking a detail-oriented and highly motivated Senior Scientist to join our High Throughput Liquid Handling Team. This role will oversee the daily operations of our automated liquid handling platforms and contribute to the continuous improvement of our compound management capabilities. About the Role Key Responsibilities: Manage high-throughput plating requests and ensure the production of high-quality MedChem compound plates. Perform daily maintenance and troubleshooting of diverse robotic systems and storage stores. Proactively identify and implement improvements to enhance system performance and reliability. Develop and maintain SOPs related to quality control. Coordinate planning and timelines with internal stakeholders. Present compound management activities and study results in cross-functional meetings. Required Skills and Experience: Proven experience in compound management within the pharmaceutical or CRO environment. Strong interest in liquid handling procedures and robotics with multi-year experience with different vendors of liquid handling equipment (e.g.: Hamilton, Tecan, Cybio…). High attention to detail and commitment to operational excellence. Strong organizational and time-management skills. Ability to work independently and collaboratively within multidisciplinary global teams. Flexibility and responsiveness to shifting priorities. Qualifications: MSc in Chemistry, Biochemistry, Engineering, or related scientific discipline. Industry experience in a laboratory setting, preferably within a Compound Management Unit. Hands-on experience with liquid handling systems and software (Venus, EvoWare, Momentum, Cellario…). Excellent written, verbal, and interpersonal communication skills. Language: English (Proficiency in German and/or French is considered a strong asset) Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10063892 Oct 08, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: The Compound Management & Engineering (CME) unit is responsible for maintaining, expanding, and distributing the compound collection used in global drug discovery projects. To support rapid and reliable delivery of thousands of stock solutions across the research community, CME relies on complex robotic systems. We are currently seeking a detail-oriented and highly motivated Senior Scientist to join our High Throughput Liquid Handling Team. This role will oversee the daily operations of our automated liquid handling platforms and contribute to the continuous improvement of our compound management capabilities. About the Role Key Responsibilities: Manage high-throughput plating requests and ensure the production of high-quality MedChem compound plates. Perform daily maintenance and troubleshooting of diverse robotic systems and storage stores. Proactively identify and implement improvements to enhance system performance and reliability. Develop and maintain SOPs related to quality control. Coordinate planning and timelines with internal stakeholders. Present compound management activities and study results in cross-functional meetings. Required Skills and Experience: Proven experience in compound management within the pharmaceutical or CRO environment. Strong interest in liquid handling procedures and robotics with multi-year experience with different vendors of liquid handling equipment (e.g.: Hamilton, Tecan, Cybio-). High attention to detail and commitment to operational excellence. Strong organizational and time-management skills. Ability to work independently and collaboratively within multidisciplinary global teams. Flexibility and responsiveness to shifting priorities. Qualifications: MSc in Chemistry, Biochemistry, Engineering, or related scientific discipline. Industry experience in a laboratory setting, preferably within a Compound Management Unit. Hands-on experience with liquid handling systems and software (Venus, EvoWare, Momentum, Cellario-). Excellent written, verbal, and interpersonal communication skills. Language: English (Proficiency in German and/or French is considered a strong asset) Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10064054 Oct 15, 2025 Switzerland Summary Oversee the execution and delivery of a portfolio of GCO supported clinical studies for Novartis, of diverse complexities and priorities, in accordance with the Clinical Development Plan (CDP) and Operational Execution Plan (OEP). The assigned portfolio is a set a clinical trials of similar types defining a Study Leadership community. Provide developmental support and guidance to Study Leaders within the community in navigating stakeholders and operational aspects of clinical trials in accordance with Standard Operating Procedures (SOPs), Good Clinical Practices (GCP), and specific country regulations. This covers all operational aspects of a clinical trial. This is a hybrid position based in Basel, Switzerland offices. About the Role Key responsibilities: Leader of a Study Leadership community. This includes people management responsibility within the Study Leadership organization Promotes operational excellence and knowledge sharing across studies. Fosters an empowered, psychologically safe organization that can navigate a matrix environment, learns, and adjusts quickly to changing conditions and business needs. Oversees people allocation (resource management) within assigned community. Oversees the execution and delivery of a portfolio of GCO supported clinical studies for Novartis of diverse complexities and priorities within the assigned community. Leads independently the Clinical Trial Team (CTT) together with the CSL in collaboration with the Clinical Operations Program Head (COPH), delivery of multiple complex global studies and promotes learning, sharing, consistent performance, and operational excellence through an agile mindset, agile principles, and a team of team-s model. Acts as the CTT product co-owner with duties and responsibilities for delivery of the operational strategy per established ways of working. Guides planning and decision making at the study level and delivers assigned clinical study/studies per the Operational Execution Plan (OEP) and clinical study protocol. Fosters an agile culture within assigned studies to achieve sprint goals and cycles, maximizing collaboration and minimizing dependencies in order to achieve long-term business impact. Essential requirements: Bachelor-s degree in life sciences/healthcare (or clinically relevant degree) is required. Advanced degree is strongly preferred. Fluent in English - oral and written 8 years of recent involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV studies of medium to highly complexity 5 years of recent contribution to and accomplishment in all aspects of conducting clinical studies of medium to highly complexity and of high priority for Novartis (e.g., planning, executing, reporting, and publishing) in a global/matrix environment in pharmaceutical industry or a contract research organization, including expert knowledge of international standards (GCP/ICH), health authorities (FDA/EMA), local/National Health Authorities regulations 5 years recent people management in a complex matrix environment. Experience in managing people globally strongly preferred Management of virtual teams. Proven ability and strong experience leading teams and building capabilities Experience in developing effective working relationships with internal and external stakeholders Excellent communicator and presenter (oral and written); ability to communicate at all levels Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams- representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10065498 Oct 31, 2025 Switzerland Summary Our ambition is to be leaders in immunology across international markets. The Executive Director International, plays a pivotal role in leading the end-to-end Rheumatology strategy for the brand, encompassing the vision, development, orchestration, implementation, and evaluation of integrated strategies across major international markets. As an enterprise leader, the ED will focus on the top three countries (Germany, Japan, and China) and Regions, driving successful launch and growth across its indications. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, and Customer & Market Activation teams to drive consistent strategy development and execution. This role represents the commercial team across different instances of the organization. About the Role Key Responsibilities International Launch Strategy: Lead the development and implementation of the launch plan for the assigned indication, ensuring alignment with overall asset strategy and corporate objectives. Cross-Functional Leadership: Orchestrate a global/international, cross-functional team (Medical, Regulatory, Access, Commercial, Supply, etc.) to deliver seamless launch execution. Launch Readiness: Assess and drive readiness across core and priority markets, identifying risks and enabling mitigation plans to ensure timely launch execution. Insight Integration: Leverage market research, competitive intelligence, and stakeholder feedback to refine positioning, messaging, and tactical planning. International-Local Partnership: Partner closely with regional and country teams to ensure pull-through of global strategy, providing guidance and tools to support in-market success. Milestone Tracking & Governance: Define and track critical launch milestones and KPIs; lead governance updates and ensure timely decision-making across key forums. Stakeholder Engagement: Effectively communicate our vision and strategic goals to senior leaders, including the International Leadership Team (ILT), Country Presidents (CP), and regional heads. Compliance & Excellence: Uphold the highest standards of compliance and launch excellence throughout all activities. Collaborate closely with global development to influence target product profile & Integrated Evidence Plan to maximize commercialization & patient access potential for the new indications and LCM in key markets in international. Lead the International Commercialization Excellence (ICE) initiatives, driving best practices in customer engagement strategies. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Essential requirements: +15 years of commercial experience across various functions in country(s) and above country, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful launches, with commercial leadership experience and therapeutic area (TA) leadership in core markets. Extensive commercial experience in immunology, especially working with rheumatologists. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches. Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM). Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leadership Capabilities: Proven ability to manage and drive performance, ensuring targets are met and exceeded in challenging markets. Demonstrated ability to lead and inspire teams, drive cross-functional collaboration, and think strategically in dynamic environments. Focuses on larger, longer-term issues, and creates plans and strategies. Comfortable in navigating the matrix and people related organizational dynamics. Establish credibility & influence across diverse stakeholders and able to navigate in an environment of shared outcomes and cross-business accountabilities. Demonstrates enterprise leadership, balance diverse stakeholders and conflicting priorities to drive results. Empowered teams to execute efficiently, through the layers of organization and across geographies. Clearly and effectively communicates with senior stakeholders (both internal &external)- to align on vision, purpose & goals. Generates trust, builds credibility and drives engagement with people and stakeholders. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division International Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Commercial & General Management Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Accountable for all country clinical/medical aspects associated with programs/trials by providing clinical strategic and tactical leadership Gathers, informs, and acts on clinical/medical/scientific insights for clinical trial concept sheets/protocols, Informed Consent Forms (ICFs) and other relevant clinical documents to optimize clinical trial implementation. Drives the identification and involvement of qualified investigators with greatest recruitment potential, identifies clinical recruitment hurdles and drives clinical recruitment activities to overcome these hurdles. Accountable for adherence to safety standards and clinical data quality in the country by providing general clinical/medical support for trial related safety findings. In close collaboration with other line functions (e.g., clinical trial operations, Medical Affairs and Patient Engagement) actively contributes to successful allocation, fast clinical trial start-up, timely recruitment, early identification of potential delays, and development and implementation of mitigation plans. About the Role Provides Clinical Development and indication expertise specific to Country, and together with the clinical trial operations team, drives the execution of clinical trials with high quality and within planned time- lines: Validates study designs, is accountable for, and makes the final decision on the clinical/medical trial and program feasibility of implementing a clinical trial protocol based on medical/clinical practice and analysis of the competitive environment in the country. Provides clinical/medical expertise to clinical trial operations team members and clinical trial sites for Institutional Review Boards (IRB)/ Ethics Committee (EC) interactions. Decides on site/Country-specific scientific/clinical/medical content of the Informed Consent Form (ICF) as needed and ensures appropriateness of patient suitable language. Provides scientific/clinical/medical expertise during interactions with Country external Experts (e.g., Regulatory Authorities, Medical Experts, Advisory Boards, Patient Advocacy Groups, etc.). Develops clinical/medical trial plans taking the broader ecosystem into account for assigned pro- grams/trials to ensure successful trial implementation, which includes: Provides robust indication, compound, and protocol training: Leverages innovation in clinical trial planning and decides on clinical/medical recruitment strategy and implementation based upon physician interviews, analysis of competitive trials, and patient engagement. Gathers, informs, and acts on insights from clinical trial Investigators/site staff, Medical Experts, patients, and payers, with internal Stakeholders at the Country level with the goal to optimize clinical trial implementation. Supports planning, implementation, and follow-up of scientific/clinical/medical components of Regulatory Authority inspections and internal audits. Reviews and resolves Country trial-related scientific/clinical/medical issues/questions. If necessary, initiates the discussion with the Global Clinical Development team. Accountable for adherence to safety standards, clinical data quality for the Country and pro- vides general scientific/clinical/medical support for safety issues: Supports the Global Clinical Development team as needed to address/clarify clinical/medical Protocol Deviations through follow-up with clinical trial sites. May support innovative study designs by identifying and conducting quality assessments of Country datasets (e.g., Registries, Electronic Health Records, Payer data, Real World Data, etc.). Role Requirements Education & Experience MD/DO or equivalent, with training in cardiology preferred. Knowledge and clinical training in siRNA desirable Protocol Execution : Demonstrates a knowledge of how to adequately review and read a protocol to understand specifics of study design and answer questions regarding the trial. Applies a detailed understanding of the drug in question to provide medical context as it relates to disease processes, populations, and standards of care. Ability to assess the feasibility of implementing the protocol based on Country medical practice and sound understanding of the overall Clinical Development Plan. Demonstrates a high level of understanding of the protocol to train others, including site personnel. Demonstrates an understanding of the protocol to evaluate compliance on the part of the Investigator/site staff/study participant and any patient safety issues. Demonstrates an understanding of Regulatory requirements and internal policies, procedures, and guidelines pertaining to clinical trials. Demonstrates current knowledge of relevant Country regulations and compliance requirements and communicates to Global teams as required.​Demonstrates knowledge of applicable SOPs, policies, procedures, and guidance documents. Expertise to represent the company as safety expert for clinical trials to external Regulatory and compliance bodies such as Regulatory Authorities, Health Boards, and REB/EC. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ulcerative colitis and Crohn's disease, along with other gastrointestinal ailments, represent a diverse array of conditions impacting millions globally. These afflictions have significant unmet medical needs and often lead to a diminished quality of life. Novartis stands at the forefront of pharmaceutical innovation in immunology, leveraging advanced scientific research to develop transformative treatments that enhance patients' lives worldwide. We are seeking a Medical Director or Executive Director of Gastrointestinal (GI) Immunology in Translational Medicine Immunology. Join us in this endeavor! You will provide medical and scientific leadership and expertise in a role that significantly impacts the drug development pipeline. 1. Drive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP) 2. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. 3. Support Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. 4. Provide scientific expert assessments and support for in-licensing opportunities, including due diligences. About the Role Major Accountabilities Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with TM TA Head and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Convene relevant (internal and external) experts to consider the proposed approach to reach TDP; present plans for approval at relevant decision boards. Be responsible for clinical portions of the Integrated Development Plan (IDP, including the Clinical Development Plan and Clinical Profiling Plan) Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Late-stage clinical projects (post-TDP, “Profiling”): In collaboration with TM TA Head or Translational Medicine Profiling Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. Drive analysis of studies and presents results to relevant decision boards. Communicate clinical team matters to GPTs and relevant BR and Development boards [and other Novartis Boards] Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Be responsible for writing TM portion of documents needed for regulatory submission through drug registration (including advisory committee and scientific advice group meetings) Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with TM TA Head, BR Research scientists, other TM line functions (BMD, CS&I, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities. This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Be accountable for compound-related biomarker strategies; works closely with Biomarker Expert in implementation. Business Development and Licensing (BD&L; in-licensing and outlicensing compounds): Participate on BD&L teams as the TM representative. In collaboration with BD&L team, evaluate the risks and benefits of potential in-licensing opportunities, identifying the strengths and weaknesses of external programs in terms of TM’s scope of responsibility. Participate in teams carrying out out-licensing of BR programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. Leadership: Lead study-specific teams/ clinical trial teams in partnership with other line functions. Lead BR-sub-team(s) on Global Project Teams for late-phase programs Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Man- agement) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific stand- ards and innovation. Key Performance Indicators Delivery of proposed Development Candidate ((B)DC) and Integrated Development Plan Approval (IDPA) milestones, and results driving decision-making for/against transition into later phase development (TDP), according to defined timelines. Delivery of Clinical pharmacology and profiling strategy including execution of studies according to timelines to support regulatory submissions and approvals. Delivery of TR plans, whether in vitro, in vivo, or in silico, to drive program strategy and clinical trial efficiency. Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results and a focus on operational excellence at all levels. Strong adherence to and modeling of Novartis values and behaviors. Impact of this role? Design and implementation of early Integrated Develop- ment Plan (IDP) and design and implementation of studies according to the IDP, enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds. This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the TDP mechanism, and driving the program after TDP by delivering key Profiling data to support regulatory submissions. Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis. Role Requirements : Education Doctoral degree, MD required in most cases. PhD or relevant scientific experience with academic track record preferred Demonstrated excellence and clinical expertise in relevant medical subspecialty. Experience/Professional Requirement: At least 5 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with level of role. Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. Demonstrated passion for science. Recognized expert in field, driving success for individual studies and projects; respected by colleagues across R&D, Development, and externally. Languages: Fluent English (oral and written). ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Oversee the execution and delivery of a portfolio of GCO supported clinical studies for Novartis, of diverse complexities and priorities, in accordance with the Clinical Development Plan (CDP) and Operational Execution Plan (OEP). The assigned portfolio is a set a clinical trials of similar types defining a Study Leadership community. Provide developmental support and guidance to Study Leaders within the community in navigating stakeholders and operational aspects of clinical trials in accordance with Standard Operating Procedures (SOPs), Good Clinical Practices (GCP), and specific country regulations. This covers all operational aspects of a clinical trial. This is a hybrid position based in Basel, Switzerland offices. About the Role Key responsibilities: Leader of a Study Leadership community. This includes people management responsibility within the Study Leadership organization Promotes operational excellence and knowledge sharing across studies. Fosters an empowered, psychologically safe organization that can navigate a matrix environment, learns, and adjusts quickly to changing conditions and business needs. Oversees people allocation (resource management) within assigned community. Oversees the execution and delivery of a portfolio of GCO supported clinical studies for Novartis of diverse complexities and priorities within the assigned community. Leads independently the Clinical Trial Team (CTT) together with the CSL in collaboration with the Clinical Operations Program Head (COPH), delivery of multiple complex global studies and promotes learning, sharing, consistent performance, and operational excellence through an agile mindset, agile principles, and a team of team’s model. Acts as the CTT product co-owner with duties and responsibilities for delivery of the operational strategy per established ways of working. Guides planning and decision making at the study level and delivers assigned clinical study/studies per the Operational Execution Plan (OEP) and clinical study protocol. Fosters an agile culture within assigned studies to achieve sprint goals and cycles, maximizing collaboration and minimizing dependencies in order to achieve long-term business impact. Essential requirements: Bachelor’s degree in life sciences/healthcare (or clinically relevant degree) is required. Advanced degree is strongly preferred. Fluent in English - oral and written 8 years of recent involvement in clinical research or drug development in an academic or industry environment spanning clinical activities in Phases I through IV studies of medium to highly complexity 5 years of recent contribution to and accomplishment in all aspects of conducting clinical studies of medium to highly complexity and of high priority for Novartis (e.g., planning, executing, reporting, and publishing) in a global/matrix environment in pharmaceutical industry or a contract research organization, including expert knowledge of international standards (GCP/ICH), health authorities (FDA/EMA), local/National Health Authorities regulations 5 years recent people management in a complex matrix environment. Experience in managing people globally strongly preferred Management of virtual teams. Proven ability and strong experience leading teams and building capabilities Experience in developing effective working relationships with internal and external stakeholders Excellent communicator and presenter (oral and written); ability to communicate at all levels Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #Li-Onsite We are looking for an enthusiastic, curious, and highly motivated proteomics expert to join our Translational Profiling (TP) team in Basel. TP is a global group of experts in proteomics, metabolomics, lipidomics, super-resolution microscopy, and data science, within Novartis Biomedical Research at our sites in Basel, Switzerland, and Cambridge, US. About the Role As a Senior Principal Scientist, you will lead a proteomics lab team, play a pivotal role in advancing our cutting-edge technologies and contribute to our global proteomics strategy, including fostering external innovation. This role involves collaboration with scientists, project teams, and five disease areas across Novartis Biomedical Research, all dedicated to creating and delivering transformative therapeutics to patients worldwide. Key Responsibilities: Initiate, lead, and oversee high-impact proteomics analyses within drug discovery programs, spanning from early research to translational studies with patient material. Initiate, lead, and contribute to interdisciplinary research programs in a collaborative and matrixed environment, working across internal cross-functional groups and with external partners. Maintain a state-of-the-art proteomics technology platform by staying current with external technology developments and aligning with internal project requirements and application priorities. Champion innovative technology and cross-disciplinary initiatives for biomedical research, enabling novel applications of proteomics technology e.g. low input and spatial proteomics. Coach and mentor junior scientists, support project teams, and facilitate the work of direct/matrix reports and key collaborators within the functional community. Essential Requirements What you will bring to the role: PhD in biology, biochemistry, or a related discipline, with at least 5-8 years' postdoctoral experience in proteomics applications in biomedical research and/or Industry experience within the pharmaceutical industry. Extensive knowledge of and experience with proteomics approaches and technologies, with key applications in biomedical and translational research as demonstrated by a strong publication record and significant contributions to the proteomics field. Good data science skills and a good understanding of biostatistics principles. Proven ability to lead a cross-functional team in a matrix environment. Collaborative, innovative mindset with the ability to adapt quickly to a dynamic, fast-paced, multi-disciplinary research environment. Exceptional communication and presentation skills for multidisciplinary audiences across various seniority and expertise levels. Desirable skills: Experience with pathway analysis and multi-omics data integration and knowledge of advanced data science approaches, including hands-on experience in Python and/or R. Experience in translational research Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10065067 Oct 17, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #Li-Onsite We are looking for an enthusiastic, curious, and highly motivated proteomics expert to join our Translational Profiling (TP) team in Basel. TP is a global group of experts in proteomics, metabolomics, lipidomics, super-resolution microscopy, and data science, within Novartis Biomedical Research at our sites in Basel, Switzerland, and Cambridge, US. About the Role As a Senior Principal Scientist, you will lead a proteomics lab team, play a pivotal role in advancing our cutting-edge technologies and contribute to our global proteomics strategy, including fostering external innovation. This role involves collaboration with scientists, project teams, and five disease areas across Novartis Biomedical Research, all dedicated to creating and delivering transformative therapeutics to patients worldwide. Key Responsibilities: Initiate, lead, and oversee high-impact proteomics analyses within drug discovery programs, spanning from early research to translational studies with patient material. Initiate, lead, and contribute to interdisciplinary research programs in a collaborative and matrixed environment, working across internal cross-functional groups and with external partners. Maintain a state-of-the-art proteomics technology platform by staying current with external technology developments and aligning with internal project requirements and application priorities. Champion innovative technology and cross-disciplinary initiatives for biomedical research, enabling novel applications of proteomics technology e.g. low input and spatial proteomics. Coach and mentor junior scientists, support project teams, and facilitate the work of direct/matrix reports and key collaborators within the functional community. Essential Requirements What you will bring to the role: PhD in biology, biochemistry, or a related discipline, with at least 5-8 years' postdoctoral experience in proteomics applications in biomedical research and/or Industry experience within the pharmaceutical industry. Extensive knowledge of and experience with proteomics approaches and technologies, with key applications in biomedical and translational research as demonstrated by a strong publication record and significant contributions to the proteomics field. Good data science skills and a good understanding of biostatistics principles. Proven ability to lead a cross-functional team in a matrix environment. Collaborative, innovative mindset with the ability to adapt quickly to a dynamic, fast-paced, multi-disciplinary research environment. Exceptional communication and presentation skills for multidisciplinary audiences across various seniority and expertise levels. Desirable skills: Experience with pathway analysis and multi-omics data integration and knowledge of advanced data science approaches, including hands-on experience in Python and/or R. Experience in translational research Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10047718 Sep 15, 2025 Switzerland Summary We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize on sharing our enterprise strategies while remaining focused on addressing the unique country-s needs as a value-added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio. An opportunity has arisen for an experienced Senior HTA Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA). This role offers the chance to lead the evidence synthesis of patient data from clinical, observational, and real-world data studies supporting HTA submissions, in a flexible and collaborative environment. The role is responsible for leading the design and execution of evidence-synthesis for HTA submissions incl. EU HTA JCA Dossier and for health economic models. Position applies methodological and analytical expertise to predict the value of Novartis assets and develop strategies on how best to demonstrate this to external decision makers. Role will strategically and effectively communicate, and tailor generated evidence to multiple stakeholder audiences. About the Role Key responsibilities: As part of the HEOR & PCO Team: Develop core global Indirect Treatment Comparison (ITC) plan for HTA, payer and other Access stakeholder assessments, submissions, and negotiations. Lead publications associated with these to meet business objectives. Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the Indirect Treatment Comparison (ITC) for local HTA submissions and support the local assessment of HTA strategy. Coordinate data requirements across evidence generations functions (Clinical Development; Medical Affairs/Biostat and HEOR & PCO) to support Pricing & Reimbursement. Set-up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables e.g., statistical analysis plans. Track key HTA statistics priorities and sequence them aligning with resource availability and risks. Identify need for preliminary ITCs to inform value proposition, development, pricing and commercial strategic forecast and decisions. Lead and facilitate the sharing of best practices and key learnings across regions, countries and cross-functional partners. Stay on top of innovative techniques, using robust analytical techniques leveraging available clinical data and published information to inform pricing and market access strategy. Collaborate with the MA Biostats team for trial analyses, HTA challenges, and statistical analyses. Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access (Therapeutic Area Access, Pricing) to ensure alignment to brand and commercial, access and evidence strategy. Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers and publications. Provide mentoring and coaching support to junior members of evidence modelling teams and across function. Essential requirements: The ideal candidate will possess a strong background in statistics, with relevant experience in HTA and clinical research. MSc/PhD in Statistics, Biostatistics, or a related field. Experience from pharmaceutical industry or life-science consultancy 6-8 years relevant experience in consultancy or pharmaceutical industry in Evidence Synthesis, Health Economics, Health Technology Assessment, or related area Strong understanding of clinical drug development and HTA-related regulations and processes Local HTA experience including experience with country HTA submissions Strong understanding of statistical methodologies for indirect treatment comparisons (ITCs) and population-adjusted indirect comparison (PAIC) Proficiency in statistical software such as R and/or SAS Strong interpersonal and scientific communication skills. Excellent problem-solving abilities and attention to detail Ability to lead in a matrix environment and work collaboratively in interdisciplinary cross-functional teams Location: This role can be based in the UK, London but also based in Basel, Switzerland and Dublin, Ireland. Benefits: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division International Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Market Access Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Clinical Development Medical Director (CDMD) is the clinical leader of a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase), or a large, complex trial, under the leadership of the (Sr.) GPCH. About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize on sharing our enterprise strategies while remaining focused on addressing the unique country’s needs as a value-added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio. An opportunity has arisen for an experienced Senior HTA Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA). This role offers the chance to lead the evidence synthesis of patient data from clinical, observational, and real-world data studies supporting HTA submissions, in a flexible and collaborative environment. The role is responsible for leading the design and execution of evidence-synthesis for HTA submissions incl. EU HTA JCA Dossier and for health economic models. Position applies methodological and analytical expertise to predict the value of Novartis assets and develop strategies on how best to demonstrate this to external decision makers. Role will strategically and effectively communicate, and tailor generated evidence to multiple stakeholder audiences. About the Role Key responsibilities: As part of the HEOR & PCO Team: Develop core global Indirect Treatment Comparison (ITC) plan for HTA, payer and other Access stakeholder assessments, submissions, and negotiations. Lead publications associated with these to meet business objectives. Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the Indirect Treatment Comparison (ITC) for local HTA submissions and support the local assessment of HTA strategy. Coordinate data requirements across evidence generations functions (Clinical Development; Medical Affairs/Biostat and HEOR & PCO) to support Pricing & Reimbursement. Set-up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables e.g., statistical analysis plans. Track key HTA statistics priorities and sequence them aligning with resource availability and risks. Identify need for preliminary ITCs to inform value proposition, development, pricing and commercial strategic forecast and decisions. Lead and facilitate the sharing of best practices and key learnings across regions, countries and cross-functional partners. Stay on top of innovative techniques, using robust analytical techniques leveraging available clinical data and published information to inform pricing and market access strategy. Collaborate with the MA Biostats team for trial analyses, HTA challenges, and statistical analyses. Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access (Therapeutic Area Access, Pricing) to ensure alignment to brand and commercial, access and evidence strategy. Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers and publications. Provide mentoring and coaching support to junior members of evidence modelling teams and across function. Essential requirements: The ideal candidate will possess a strong background in statistics, with relevant experience in HTA and clinical research. MSc/PhD in Statistics, Biostatistics, or a related field. Experience from pharmaceutical industry or life-science consultancy 6-8 years relevant experience in consultancy or pharmaceutical industry in Evidence Synthesis, Health Economics, Health Technology Assessment, or related area Strong understanding of clinical drug development and HTA-related regulations and processes Local HTA experience including experience with country HTA submissions Strong understanding of statistical methodologies for indirect treatment comparisons (ITCs) and population-adjusted indirect comparison (PAIC) Proficiency in statistical software such as R and/or SAS Strong interpersonal and scientific communication skills. Excellent problem-solving abilities and attention to detail Ability to lead in a matrix environment and work collaboratively in interdisciplinary cross-functional teams Location: This role can be based in the UK, London but also based in Basel, Switzerland and Dublin, Ireland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Reporting to the Region Europe V&A Head, with a dotted line to the Cluster Head, the ED is an active member of both the SERCE leadership team and the Region Europe Access leadership team and provides strategic direction to access leaders in each cluster country. The Executive Director, Value and Access for the SERCE Cluster leads the value and access function across the cluster, driving excellence in market access, pricing, & reimbursement. This senior leader is responsible for executing integrated access strategies to ensure optimal patient access to innovative medicines, aligning with International and Regional priorities while adapting to local market dynamics. The role also focuses on building and developing high-performing teams, fostering cross-functional collaboration, and shaping the external environment to support sustainable access. About the Role Key Responsibilities: Roll-out of the V&A deliverables to cluster countries and work in close collaboration with International V&A and the Region Europe V&A team​. Improve the collaboration with International V&A to ensure the needs of Cluster countries are communicated early on to help shape market access strategies, including HEOR. Utilizes sound understanding and knowledge of local healthcare systems to support countries in development and execution of V&A strategies. In close collaboration with International Pricing, chairs the Cluster pricing governance approval process.Partners with Medical Affairs, Commercial, Regulatory, Public Affairs, Communications & Patient Engagement to ensure robust launch readiness plans and integrated approaches to access. Build and maintain relationships with key external stakeholders (payers, HTA bodies, government agencies, patient organizations) to advocate for patient access and shape policy. Monitors and influences healthcare policy developments impacting access, collaborating with public affairs to create a favorable access environment. Represent Novartis in external governmental, payer, HTA, and patient advocacy forums, actively promoting access-related initiatives, shaping evidentiary standards, and supporting innovation in market access and patient outcomes through education and policy engagement. Accountable for access performance management, incl. metrics & KPIs being updated and relevant, and that are being tracked and impacted at each cluster country level with appropriate International support for all therapeutic areas. ​Role models ethical standards and contribute proactively to a credible image for Novartis in the Cluster. Leads and develops the value and access team, fostering leadership, talent, and critical capabilities across the cluster. Optimizes Value and Access resources and allocation: Advocates early resourcing where and when appropriate, while ensuring cost adherence in spend of V&A activities and resourcing. Ability to articulate and defend priorities and needs of access with strong influencing skills. Ensures all access activities adhere to governance, compliance, quality, and ethical standards. Essential requirements: At least 15 years of experience in the pharmaceutical industry, with significant senior leadership experience in market access, pricing, reimbursement, or health policy. Advanced degree in life sciences, health economics, public health, or related field; business qualification (e.g., MBA) is desirable. Experience in both country and regional/global roles; strong knowledge of key European markets and HTA-based systems. Proven track record in developing and executing access strategies and leading cross-functional teams. Strong business acumen, superior leadership, and influencing skills. Strategic and enterprise thinking, with flexibility to manage complexity. Location: This role is based in Basel, Switzerland Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Reporting to the Region Europe V&A Head, with a dotted line to the Cluster Head, the ED is an active member of both the WEC leadership team and the Region Europe Access leadership team and provides strategic direction to access leaders in each cluster country. The Executive Director, Value and Access for the WEC Cluster leads the value and access function across the cluster, driving excellence in market access, pricing, & reimbursement. This senior leader is responsible for executing integrated access strategies to ensure optimal patient access to innovative medicines, aligning with International and Regional priorities while adapting to local market dynamics. The role also focuses on building and developing high-performing teams, fostering cross-functional collaboration, and shaping the external environment to support sustainable access. About the Role Key Responsibilities: Roll-out of the V&A deliverables to cluster countries and work in close collaboration with International V&A and the Region Europe V&A team. Improve the collaboration with International V&A to ensure the needs of Cluster countries are communicated early on to help shape market access strategies, including HEOR. Utilizes sound understanding and knowledge of local healthcare systems to support countries in development and execution of V&A strategies. ​ In close collaboration with International Pricing, chairs the Cluster pricing governance approval process.Partners with Medical Affairs, Commercial, Regulatory, Public Affairs, Communications & Patient Engagement to ensure robust launch readiness plans and integrated approaches to access. ​Build and maintain relationships with key external stakeholders (payers, HTA bodies, government agencies, patient organizations) to advocate for patient access and shape policy. Monitors and influences healthcare policy developments impacting access, collaborating with public affairs to create a favorable access environment. Represent Novartis in external governmental, payer, HTA, and patient advocacy forums, actively promoting access-related initiatives, shaping evidentiary standards, and supporting innovation in market access and patient outcomes through education and policy engagement. Accountable for access performance management, incl. metrics & KPIs being updated and relevant, and that are being tracked and impacted at each cluster country level with appropriate International support for all therapeutic areas. Role models ethical standards and contribute proactively to a credible image for Novartis in the Cluster. Leads and develops the value and access team, fostering leadership, talent, and critical capabilities across the cluster. Optimizes Value and Access resources and allocation: Advocates early resourcing where and when appropriate, while ensuring cost adherence in spend of V&A activities and resourcing. Ability to articulate and defend priorities and needs of access with strong influencing skills. Ensures all access activities adhere to governance, compliance, quality, and ethical standards. Essential requirements: At least 15 years of experience in the pharmaceutical industry, with significant senior leadership experience in market access, pricing, reimbursement, or health policy. Advanced degree in life sciences, health economics, public health, or related field; business qualification (e.g., MBA) is desirable. Experience in both country and regional/global roles; strong knowledge of key European markets and HTA-based systems. Proven track record in developing and executing access strategies and leading cross-functional teams. Strong business acumen, superior leadership, and influencing skills. Strategic and enterprise thinking, with flexibility to manage complexity. Location: This role is based in Basel, Switzerland Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #Li-onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. As an In-vivo Research Scientist in the Immunology Disease Unit in Biomedical Research, you will play a pivotal role contributing to and being responsible for conducting a variety of complex research activities under the guidance of the lab head to help achieve the objectives of the immunology program. About the Role Key responsibilities of the role will include designing, overseeing, and conducting in vivo studies in rodents focused on autoimmune diseases or mechanistic PK/PD models. This involves tasks such as dosing, monitoring, scoring, and collecting samples. In addition, key responsibilities include performing ex vivo readouts such as cytokine and biomarker profiling, flow cytometry and histological evaluations to complement in vivo findings. The Research Scientist also analyzes experimental data, interprets findings, proposes innovative strategies to advance research, and maintains meticulous experimental records. Additionally, you will be responsible for prioritising tasks effectively, meeting project deadlines, and ensuring compliance with safety protocols and regulatory standards. Minimum Requirements: What you will bring to the role Your Profile: · Completed apprenticeship as a laboratory technician or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field · Minimum 2-3 years relevant lab based work experience in an industrial or academic setting, preferably in immunology research with in-vivo research as a focus LTK I or equivalent animal research qualification is essential. Research Techniques and Expertise: Proficiency in mouse models and handling techniques, including blood sampling, oral gavage, injections (IV/IP/ID/SC), perfusion, organ harvesting, anesthesia, and euthanasia Proficiency with planning and running mechanistic PK/PD in vivo models and / or disease models related to immune indications Proficiency in cellular immunology methods and ex vivo readouts such as ELISA, multiplex assays. Multicolour flow cytometry and qPCR experience would be an advantage Experience working with human cell transfer (PBMCs) and humanised mouse models is of advantage Analytical and Organizational Skills: Maintains experimental records and prepares reports aligned with study objectives and compliance guidelines Demonstrates strong planning and organizational skills, including prioritizing tasks, allocating resources, and meeting deadlines Eager to learn and combine new techniques and concepts, to present results within the lab and project teams, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Adapts quickly to new concepts and applies insights to drive innovative research solutions Excellent oral and written English *Restrictions on flexible working arrangements may apply and will be discussed at interview if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10064204 Oct 23, 2025 Switzerland Summary Join a dynamic team where you will be managing high-impact patent litigation cases. You'll work closely with both in-house and external counsel, driving strategic litigation efforts and overseeing key operational processes. This role offers the opportunity to lead projects that enhance litigation workflows, contribute to budget planning, and deliver insightful IP reporting-making a real difference in how we protect and leverage our intellectual property. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities : Provides and utilizes IP expertise to support several IP Counsels and the IP function as a whole - championing quality, collaboration and operational excellence in the Department. Contributes to the implementation and application of IP policies and guidelines - providing non-legal advice to business colleagues, collaborating with the business under the supervision of project leads to ensure business goals are met in an efficient and timely manner. Contributes to the #OneNovartisIP culture - Proactively and autonomously supports in-house patent litigation counsel and attorneys in preparation for patent enforcement and defense, by interacting with local counsel and local Business Franchises. Maintain and share advanced knowledge of latest litigation rules and adapting practices to comply. Monitor and updating Anaqua on a daily basis. Communicate effectively with colleagues, agents and other associates - Actively participate in litigation group and cross-divisional meetings as needed - being flexible to provide support in other areas within the Patent Support team (i.e. invoicing and data input). Leads teams in development of procedures and processes - ability to conduct meetings as needed; Recommends areas/systems of possible improvement in efficiencies in procedures. Leads projects relating to litigation processes/operations, driving the successful implementation of new and revised processes and guidelines. Autonomously supports in-house patent litigation counsel and attorneys on matters such as patent ownership and licensing structure. Manages the flow of information by acting as a contact point for local lawyers/local team for patent litigation matters - using Litigation database document and information management; familiarity with patent databases e.g. PatBase, Espacenet, etc. Attend and draft memorandum of litigation meetings with local counsel and local business, provide action points and follow up on agreed objectives. Manages the IP Litigation budget process; drive the preparation of and deliver the various litigation budget forecasts by liaising with internal and external attorneys & counsel, as well as BPA, assisting in the review, as appropriate. Responsible for full project life cycle including Liaises with department eBilling coordinator, utilizes Anaqua to record and report litigation matters, litigation reporting and leads the interactions on behalf of IP Litigation Project Team with any third-party co-owners, licensors, patentees. Supervision of junior litigation paralegals, local litigation team coordinators and new team members providing guidance on internal and external processes, litigation database management, etc. Essential Requirements: Relevant degree, or equivalent experience. Paralegal qualification/ certifications or equivalent Proficiency in English required - spoken & written, other languages is an asset. Demonstrated professional experience as an IP paralegal or equivalent in an IP litigation law firm or corporation. Extensive experience in autonomously providing complex patent litigation support in a large multinational company preferably in-house, or in a law firm. Able to work autonomously in preparation of draft schedules and supporting documents for subsequent attorney review - able to communicate with business clients in multiple countries. Excellent team-player with exemplary interpersonal skills - Reliable, service-oriented with impeccable integrity and willingness to learn. Proven ability to balance and identify priorities in daily work, manage varying workload levels, ensuring a consistent work product, and support the IP team efficiently and in a solution-oriented, contextualized manner. Proactive approach to project/workstream involvement. Able to consider the needs of the team and where they can contribute, implementing or suggesting solutions prior to being instructed. Active participation in relevant projects - willingness to learn and develop in role. Extensive experience in autonomously managing complex patent litigation support in a large multinational company, preferably in-house, or in a law firm. IP Identified leadership potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary As a translational medicine expert (TME), you provide medical and scientific expertise and leadership to: • Drive success of early global programs, develop and implement strategies to transition to late-stage development. • Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. • Support translational research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. • Provide scientific expert assessments and support for in-licensing opportunities, including due diligence About the Role This hybrid role can be based in Basel, Switzerland, or London, United Kingdom. About the role: As a Dermatology TME, you will report to the Dermatology TM Head and collaborate with other experienced TMEs in Translational Medicine Discovery & Profiling (TMDP) to develop high value decision-strategies for the Translational Medicine component of drug development projects and lead global cross-functional project teams through the early clinical phase. Job Description Key Responsibilities: Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with other experienced TMEs, and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from research to late-stage transition in single or multiple indications, including indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Late-stage clinical projects (“Profiling”): Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials. Drive analysis of studies and presents results to relevant decision boards. Be responsible for writing TM portions of documents needed for regulatory submission through drug registration. Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with Dermatology TM Head, BR Research scientists, other TM line functions (biomarker, clinical operations, preclinical safety and pharmacokinetics) develop strategies to identify initial or expansion (indications). This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Business Development and Licensing (BD&L; in-licensing and out licensing compounds): Participate in BD&L teams as the TM representative. Participate in teams carrying out licensing of programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. General responsibilities: Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study. Provides medical and scientific leadership and expertise to all line functions on the study team. Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders (e.g. payers, patient advocacy groups). Oversee publication strategy for TM studies; lead writing of scientific publications; present study results externally where appropriate. Lead study-specific teams/ clinical trial teams in partnership with other line functions and collaborate closely with other TM (especially clinical operations) and non-TM (especially Project Management) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific standards and innovation. Essential Requirements: This position will be located at the Cambridge, MA, London, UK or Basel, Switzerland site and will not have the ability to be located remotely. This position will require approximately 7% travel as defined by the business (domestic and/ or international). This is a dual posting*. The final level and title of the offer role would be determined by the hiring team based on the skills, experience, and capabilities required to perform the role at the level the role has been offered (Associate Director / Director). Doctoral degree, MD required with clinical subspecialty training in dermatological diseases; Additional PhD/post-doctoral equivalent research and relevant Board certification preferred. Associate Director Level: 1-2 years of experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience; Director Level: 5+ years of experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with the level of the role. Innovation: Seeks out new clinical discovery opportunities and approaches to accelerate programs. Leadership of Collaborations: Able to lead multidisciplinary teams in a matrix organization. Team player mentality and willingness to collaborate and interact with the other TMEs. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059999 Oct 06, 2025 Switzerland Summary As a translational medicine expert (TME), you provide medical and scientific expertise and leadership to: Drive success of early global programs, develop and implement strategies to transition to late-stage development. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. Support translational research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. Provide scientific expert assessments and support for in-licensing opportunities, including due diligence About the Role This hybrid role can be based in Basel, Switzerland, or London, United Kingdom. About the role: As a Dermatology TME, you will report to the Dermatology TM Head and collaborate with other experienced TMEs in Translational Medicine Discovery & Profiling (TMDP) to develop high value decision-strategies for the Translational Medicine component of drug development projects and lead global cross-functional project teams through the early clinical phase. Job Description Key Responsibilities: Early clinical projects (Phase I / II, -Discovery-): Develop, in collaboration with other experienced TMEs, and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from research to late-stage transition in single or multiple indications, including indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Late-stage clinical projects (-Profiling-): Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials. Drive analysis of studies and presents results to relevant decision boards. Be responsible for writing TM portions of documents needed for regulatory submission through drug registration. Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with Dermatology TM Head, BR Research scientists, other TM line functions (biomarker, clinical operations, preclinical safety and pharmacokinetics) develop strategies to identify initial or expansion (indications). This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Business Development and Licensing (BD&L; in-licensing and out licensing compounds): Participate in BD&L teams as the TM representative. Participate in teams carrying out licensing of programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. General responsibilities: Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study. Provides medical and scientific leadership and expertise to all line functions on the study team. Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders (e.g. payers, patient advocacy groups). Oversee publication strategy for TM studies; lead writing of scientific publications; present study results externally where appropriate. Lead study-specific teams/ clinical trial teams in partnership with other line functions and collaborate closely with other TM (especially clinical operations) and non-TM (especially Project Management) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific standards and innovation. Essential Requirements: This position will be located at the Cambridge, MA, London, UK or Basel, Switzerland site and will not have the ability to be located remotely. This position will require approximately 7% travel as defined by the business (domestic and/ or international). This is a dual posting*. The final level and title of the offer role would be determined by the hiring team based on the skills, experience, and capabilities required to perform the role at the level the role has been offered (Associate Director / Director). Doctoral degree, MD required with clinical subspecialty training in dermatological diseases; Additional PhD/post-doctoral equivalent research and relevant Board certification preferred. Associate Director Level: 1-2 years of experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience; Director Level: 5+ years of experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with the level of the role. Innovation: Seeks out new clinical discovery opportunities and approaches to accelerate programs. Leadership of Collaborations: Able to lead multidisciplinary teams in a matrix organization. Team player mentality and willingness to collaborate and interact with the other TMEs. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture&nbsp ; You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10063994 Oct 07, 2025 Switzerland Summary Welcome to where we thrive together! Are you ready to join a community where you can make a real impact on the world by supporting the global pipeline of the Immunology TA across all phases of development? At Novartis, we believe in creating a positive and inclusive work environment where we can solve the toughest healthcare challenges together. About the Role Location: Basel, Switzerland or London, UK This hybrid role can be based in Basel, Switzerland or in London, UK Key responsibilities: Defines team goals, or provides matrix leadership, aligns and provides input to department strategy to project team or company initiative. Assumes responsibility for project or initiative results, and builds a clear connection to department and company goals. Successfully leads or operationalizes key scientific/technical/development areas from the discipline to advance department and company goals. Leads PKS sub-team(s) to generate, analyze, integrate data. Works with teams to identify potential project hurdles and identifies mitigation plan (eg, resource needs, strategic alignment). Champions and advances new science relevant for project/department goals. Completes all required organizational trainings and requirements according to corporate timelines. Adhere in strict accord to the appropriate SOP and GxP guidelines. May develop and lead innovative interdisciplinary team, and/or leads through matris using a well-developed internal and external scientific network. Generates innovative strategy input and project concepts across multiple scientific/technical/development domains. Links scientific strategy with specific objectives in novel areas through flexible matrix communities and/or direct team leadership and empowerment. Conducts long-and mid-term planning to identify specific, measurable impact on team objectives. Skilled in collaboration across PKS-internal or external business partners. Utilizes established networks and builds new network connections to bring new knowledge into the department/TM/NIBR/GDD. Essential Requirements : PhD / Pharm.D. level scientist with relevant experience in drug metabolism and pharmacokinetics or related biologic background. Relevant TA/DA experience and demonstrated track record on coaching and mentoring of associates would be preferred 5+ years of experience in drug development functions (e.g. DMPK, Clinical Pharmacology) with a minimum of 5 years- experience within a relevant LF in industry, academia or regulatory agency Extensive and in-depth knowledge of drug metabolism and pharmacokinetics including pharmacology PK and PK/PD evaluation, immunogenicity assessments and regulatory requirements. Demonstrated success leading and influencing in a multi-disciplinary environment including global project teams. Aware of the most recent developments in drug development sciences and the implications for current projects. Strong coaching, mentoring and people management skills Desirable Requirements: Proven record as team player/leader with excellent influencing & negotiation skills. Excellent organizational and project skills Commitment to Diversity and Inclusion / EEO paragraph: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and Accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Global Program Clinical Head (GPCH) in CVM is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy About the Role This role can be based in London or Basel Major accountabilities: Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on Biomedical Research clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-DDP, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. What you’ll bring to the role: MD or equivalent (preferred) PhD, or PharmD degree required 6 years professional experience with (MD or equivalent) OR 10 years (PhD or PharmD) of involvement in clinical research or drug development in an industry environment spanning clinical activities in Phases I through III/IV, including submission dossiers required Cardiovascular disease expertise, ideally experience with Cardio-Immunology or inflammasome Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Experience with submissions and health authorities required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10065689 Nov 03, 2025 Switzerland Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary #LI-Onsite Location: Schweizerhalle, Switzerland Am Novartis Produktionsstandort in der Schweizerhalle befindet sich unser Engineering-Team, welches Verstärkung sucht. Zur Verantwortung zählt, dass Prozesse reibungslos und zuverlässig ablaufen. Zudem sind wir verantwortlich für die Prozessleit- und Automatisierungsysteme in der chemischen Produktion, arbeiten in Projekten mit und führen Wartungstätigkeiten durch. Wir glauben an die Kraft neugieriger, ambitionierter und teamorientierter Persönlichkeiten. In einem inspirierenden Umfeld gestalten Sie gemeinsam mit uns die Zukunft, treffen mutige Entscheidungen und entwickeln innovative Lösungen. Bewerben Sie sich jetzt – und werden Sie Teil eines Teams, das Ihre Expertise schätzt und Sie als Mensch und Fachkraft voll unterstützt. About the Role Ihre Aufgaben sind unter anderem: Sicherstellung der technischen Verfügbarkeit der zugewiesenen Automatisierungssysteme, Prozessleitsysteme, Anlagen und Gebäudeinfrastrukturen sowie der Kosteneffizienz innerhalb der festgelegten Grenzen. Funktion als SME für Projekte im Verantwortungsbereich Sie übernehmen die Planung, Durchführung und Dokumentation von Wartungs- und Kalibrierungsaktivitäten, Ursachenanalysen bei Abweichungen sowie die technische Betreuung und Koordination von internen und externen Technikern. Vorantreiben der Digitalisierung und Innovation im Verantwortungsbereich. Unterstützung der Prozessharmonisierung im Rheintal, um effizientes Arbeiten zu ermöglichen. Unterstützen Sie interne und externe Audits und stellen Sie GMP- und HSE-Compliance ohne kritische Feststellungen sicher. Vorantreiben von Initiativen zur kontinuierlichen Verbesserung, um sicherzustellen, dass Anlagen, Automatisierungssysteme und Prozesse unsere Geschäftsanforderungen optimal unterstützen (Kosteneffizienz, Anlagenverfügbarkeit, Produktqualität, Einhaltung von GMP- und HSE-Vorschriften). Proaktive Auswahl und Verwaltung der zugewiesenen externen Ressourcen innerhalb der vorgegebenen Budgetgrenzen, um ein optimales Preis-Leistungs-Verhältnis zu gewährleisten. Leitung oder Mitwirkung an Projekten zur Verbesserung von Systemen, Versorgungseinrichtungen und Anlagen (z. B. Energieeffizienz, Produktivität, Einhaltung von Umweltvorschriften, Wartung). Was Sie für die Position mitbringen: Abgeschlossenes Studium in Automatisierungstechnik / Elektrotechnik (FH/HF) oder vergleichbare technische Ausbildung. Fünf Jahre Erfahrung als Ingenieur im Bereich Automatisierung vorzugsweise in der chemischen oder pharmazeutischen Industrie. Nachweisliche Erfahrung in der Lösung von Software-/Automatisierungsproblemen und der Aufrechterhaltung eines zuverlässigen Betriebs aller Gebäudesteuerungs-/Automatisierungssysteme und verwandter Systeme unter Einhaltung und Unterstützung globaler Standards. Kenntnisse in Commissioning and Qualification innerhalb der Automatisierung (CSV). Umfassende Kenntnisse von GxP-/HSE- und Qualitätssystemen. Kenntnisse und Erfahrungen mit Prozessleitsystemen (vorzugsweise Emerson DeltaV, Von Vorteil: Kenntnisse Aveva PI-System, Siemens TIA-Portal). Fundierte IT- und Netzwerk-kenntnisse. Bereitschaft zu Bereitschaftsdiensten am Wochenende. Sprachkenntnisse: Deutsch und Englisch. Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Stellen Sie sich vor, was Sie bei Novartis tun könnten! Engagement für Vielfalt und Inklusion: Novartis setzt sich für Vielfalt, Chancengleichheit und Inklusion ein. Wir sind bestrebt, vielfältige Teams zusammenzustellen, die für die Patienten und Gemeinschaften repräsentativ sind, denen wir dienen. Wir bemühen uns um die Schaffung eines inklusiven Arbeitsplatzes, der durch Zusammenarbeit mutige Innovationen fördert und unsere Mitarbeiter in die Lage versetzt, ihr volles Potenzial zu entfalten. Unsere Einstellungsentscheidungen basieren auf Chancengleichheit und der besten Qualifikation, ungeachtet von Geschlecht, Religion, Alter, Hautfarbe, Rasse, sexueller Orientierung, Nationalität oder Behinderung. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10063877 Oct 24, 2025 Switzerland Summary #LI-Onsite Location: Schweizerhalle, Switzerland Am Novartis Produktionsstandort in der Schweizerhalle befindet sich unser Engineering-Team, welches Verstärkung sucht. Zur Verantwortung zählt, dass Prozesse reibungslos und zuverlässig ablaufen. Zudem sind wir verantwortlich für die Prozessleit- und Automatisierungsysteme in der chemischen Produktion, arbeiten in Projekten mit und führen Wartungstätigkeiten durch. Wir glauben an die Kraft neugieriger, ambitionierter und teamorientierter Persönlichkeiten. In einem inspirierenden Umfeld gestalten Sie gemeinsam mit uns die Zukunft, treffen mutige Entscheidungen und entwickeln innovative Lösungen. Bewerben Sie sich jetzt - und werden Sie Teil eines Teams, das Ihre Expertise schätzt und Sie als Mensch und Fachkraft voll unterstützt. About the Role Ihre Aufgaben sind unter anderem: Sicherstellung der technischen Verfügbarkeit der zugewiesenen Automatisierungssysteme, Prozessleitsysteme, Anlagen und Gebäudeinfrastrukturen sowie der Kosteneffizienz innerhalb der festgelegten Grenzen. Funktion als SME für Projekte im Verantwortungsbereich Sie übernehmen die Planung, Durchführung und Dokumentation von Wartungs- und Kalibrierungsaktivitäten, Ursachenanalysen bei Abweichungen sowie die technische Betreuung und Koordination von internen und externen Technikern. Vorantreiben der Digitalisierung und Innovation im Verantwortungsbereich. Unterstützung der Prozessharmonisierung im Rheintal, um effizientes Arbeiten zu ermöglichen. Unterstützen Sie interne und externe Audits und stellen Sie GMP- und HSE-Compliance ohne kritische Feststellungen sicher. Vorantreiben von Initiativen zur kontinuierlichen Verbesserung, um sicherzustellen, dass Anlagen, Automatisierungssysteme und Prozesse unsere Geschäftsanforderungen optimal unterstützen (Kosteneffizienz, Anlagenverfügbarkeit, Produktqualität, Einhaltung von GMP- und HSE-Vorschriften). Proaktive Auswahl und Verwaltung der zugewiesenen externen Ressourcen innerhalb der vorgegebenen Budgetgrenzen, um ein optimales Preis-Leistungs-Verhältnis zu gewährleisten. Leitung oder Mitwirkung an Projekten zur Verbesserung von Systemen, Versorgungseinrichtungen und Anlagen (z. B. Energieeffizienz, Produktivität, Einhaltung von Umweltvorschriften, Wartung). Was Sie für die Position mitbringen: Abgeschlossenes Studium in Automatisierungstechnik / Elektrotechnik (FH/HF) oder vergleichbare technische Ausbildung. Fünf Jahre Erfahrung als Ingenieur im Bereich Automatisierung vorzugsweise in der chemischen oder pharmazeutischen Industrie. Nachweisliche Erfahrung in der Lösung von Software-/Automatisierungsproblemen und der Aufrechterhaltung eines zuverlässigen Betriebs aller Gebäudesteuerungs-/Automatisierungssysteme und verwandter Systeme unter Einhaltung und Unterstützung globaler Standards. Kenntnisse in Commissioning and Qualification innerhalb der Automatisierung (CSV). Umfassende Kenntnisse von GxP-/HSE- und Qualitätssystemen. Kenntnisse und Erfahrungen mit Prozessleitsystemen (vorzugsweise Emerson DeltaV, Von Vorteil: Kenntnisse Aveva PI-System, Siemens TIA-Portal). Fundierte IT- und Netzwerk-kenntnisse. Bereitschaft zu Bereitschaftsdiensten am Wochenende. Sprachkenntnisse: Deutsch und Englisch. Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Stellen Sie sich vor, was Sie bei Novartis tun könnten! Engagement für Vielfalt und Inklusion: Novartis setzt sich für Vielfalt, Chancengleichheit und Inklusion ein. Wir sind bestrebt, vielfältige Teams zusammenzustellen, die für die Patienten und Gemeinschaften repräsentativ sind, denen wir dienen. Wir bemühen uns um die Schaffung eines inklusiven Arbeitsplatzes, der durch Zusammenarbeit mutige Innovationen fördert und unsere Mitarbeiter in die Lage versetzt, ihr volles Potenzial zu entfalten. Unsere Einstellungsentscheidungen basieren auf Chancengleichheit und der besten Qualifikation, ungeachtet von Geschlecht, Religion, Alter, Hautfarbe, Rasse, sexueller Orientierung, Nationalität oder Behinderung. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary #LI-Onsite Location: Schweizerhalle, Switzerland Am Novartis Produktionsstandort in der Schweizerhalle befindet sich unser Engineering-Team, welches Verstärkung sucht. Zur Verantwortung zählt, dass Prozesse reibungslos und zuverlässig ablaufen. Parallel dazu übernehmen Sie Verantwortung für Instandhaltungs- und Kalibrierungsaufgaben, stellen sicher, dass Anlagen optimal funktionieren, und führen Inbetriebnahmen für reibungslose Starts und die Einhaltung von Standards an. Wenn Sie ein praxisorientierter Problemlöser sind, der Verantwortung, Qualität und kontinuierliche Verbesserung schätzt, bietet sich Ihnen hier die Chance, vom ersten Tag an spürbaren Einfluss zu nehmen. Wir glauben an die Kraft neugieriger, ambitionierter und teamorientierter Persönlichkeiten. In einem inspirierenden Umfeld gestalten Sie gemeinsam mit uns die Zukunft, treffen mutige Entscheidungen und entwickeln innovative Lösungen. Bewerben Sie sich jetzt – und werden Sie Teil eines Teams, das Ihre Expertise schätzt und Sie als Mensch und Fachkraft voll unterstützt. About the Role Ihre Aufgaben sind unter anderem: Führen Sie Verbesserungen an Anlagen, Versorgungseinrichtungen und Gebäuden durch oder tragen Sie dazu bei (Energieeffizienz, Produktivität, Umweltkonformität, Instandhaltung). Sie übernehmen die Planung, Durchführung und Dokumentation von Wartungs- und Kalibrierungsaktivitäten, Ursachenanalysen bei Abweichungen sowie die technische Betreuung und Koordination von internen und externen Technikern. Unterstützen und leiten Sie interne und externe Audits und stellen Sie GMP- und HSE-Compliance ohne kritische Feststellungen sicher. Leitung oder Mitwirkung an Projekten zur Verbesserung von Ausrüstung, Versorgungseinrichtungen und Anlagen (z. B. Energieeffizienz, Produktivität, Einhaltung von Umweltvorschriften, Wartung). Erstellung, Überprüfung und Genehmigung von Zeichnungen, Listen, Zeitplänen, Diagrammen, Layouts, Berechnungen und Datenblättern im Projekt. Kosteneffiziente technische Lösungen im Verantwortungsbereich. Was Sie für die Position mitbringen: Fünf Jahre Erfahrung als Betriebsingenieur im technischen, vorzugsweise in der chemischen oder pharmazeutischen Industrie. Technische Grundausbildung vorzugsweise mit einer Weiterbildung als Techniker HF/FH. Projektmanagement-Fähigkeiten sowie fundiertes technisches Fachwissen. Kenntnisse in Commissioning und Qualifizierung. Sie vermitteln komplexe technische Inhalte klar und verständlich – auch gegenüber dem Management und anderen Fachbereichen. Umfassende Kenntnisse von GxP-/HSE- und Qualitätssystemen. Sprachkenntnisse: Deutsch und Englisch. Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Stellen Sie sich vor, was Sie bei Novartis tun könnten! Engagement für Vielfalt und Inklusion: Novartis setzt sich für Vielfalt, Chancengleichheit und Inklusion ein. Wir sind bestrebt, vielfältige Teams zusammenzustellen, die für die Patienten und Gemeinschaften repräsentativ sind, denen wir dienen. Wir bemühen uns um die Schaffung eines inklusiven Arbeitsplatzes, der durch Zusammenarbeit mutige Innovationen fördert und unsere Mitarbeiter in die Lage versetzt, ihr volles Potenzial zu entfalten. Unsere Einstellungsentscheidungen basieren auf Chancengleichheit und der besten Qualifikation, ungeachtet von Geschlecht, Religion, Alter, Hautfarbe, Rasse, sexueller Orientierung, Nationalität oder Behinderung. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10063874 Oct 24, 2025 Switzerland Summary #LI-Onsite Location: Schweizerhalle, Switzerland Am Novartis Produktionsstandort in der Schweizerhalle befindet sich unser Engineering-Team, welches Verstärkung sucht. Zur Verantwortung zählt, dass Prozesse reibungslos und zuverlässig ablaufen. Parallel dazu übernehmen Sie Verantwortung für Instandhaltungs- und Kalibrierungsaufgaben, stellen sicher, dass Anlagen optimal funktionieren, und führen Inbetriebnahmen für reibungslose Starts und die Einhaltung von Standards an. Wenn Sie ein praxisorientierter Problemlöser sind, der Verantwortung, Qualität und kontinuierliche Verbesserung schätzt, bietet sich Ihnen hier die Chance, vom ersten Tag an spürbaren Einfluss zu nehmen. Wir glauben an die Kraft neugieriger, ambitionierter und teamorientierter Persönlichkeiten. In einem inspirierenden Umfeld gestalten Sie gemeinsam mit uns die Zukunft, treffen mutige Entscheidungen und entwickeln innovative Lösungen. Bewerben Sie sich jetzt - und werden Sie Teil eines Teams, das Ihre Expertise schätzt und Sie als Mensch und Fachkraft voll unterstützt. About the Role Ihre Aufgaben sind unter anderem: Führen Sie Verbesserungen an Anlagen, Versorgungseinrichtungen und Gebäuden durch oder tragen Sie dazu bei (Energieeffizienz, Produktivität, Umweltkonformität, Instandhaltung). Sie übernehmen die Planung, Durchführung und Dokumentation von Wartungs- und Kalibrierungsaktivitäten, Ursachenanalysen bei Abweichungen sowie die technische Betreuung und Koordination von internen und externen Technikern. Unterstützen und leiten Sie interne und externe Audits und stellen Sie GMP- und HSE-Compliance ohne kritische Feststellungen sicher. Leitung oder Mitwirkung an Projekten zur Verbesserung von Ausrüstung, Versorgungseinrichtungen und Anlagen (z. B. Energieeffizienz, Produktivität, Einhaltung von Umweltvorschriften, Wartung). Erstellung, Überprüfung und Genehmigung von Zeichnungen, Listen, Zeitplänen, Diagrammen, Layouts, Berechnungen und Datenblättern im Projekt. Kosteneffiziente technische Lösungen im Verantwortungsbereich. Was Sie für die Position mitbringen: Fünf Jahre Erfahrung als Betriebsingenieur im technischen, vorzugsweise in der chemischen oder pharmazeutischen Industrie. Technische Grundausbildung vorzugsweise mit einer Weiterbildung als Techniker HF/FH. Projektmanagement-Fähigkeiten sowie fundiertes technisches Fachwissen. Kenntnisse in Commissioning und Qualifizierung. Sie vermitteln komplexe technische Inhalte klar und verständlich - auch gegenüber dem Management und anderen Fachbereichen. Umfassende Kenntnisse von GxP-/HSE- und Qualitätssystemen. Sprachkenntnisse: Deutsch und Englisch. Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Stellen Sie sich vor, was Sie bei Novartis tun könnten! Engagement für Vielfalt und Inklusion: Novartis setzt sich für Vielfalt, Chancengleichheit und Inklusion ein. Wir sind bestrebt, vielfältige Teams zusammenzustellen, die für die Patienten und Gemeinschaften repräsentativ sind, denen wir dienen. Wir bemühen uns um die Schaffung eines inklusiven Arbeitsplatzes, der durch Zusammenarbeit mutige Innovationen fördert und unsere Mitarbeiter in die Lage versetzt, ihr volles Potenzial zu entfalten. Unsere Einstellungsentscheidungen basieren auf Chancengleichheit und der besten Qualifikation, ungeachtet von Geschlecht, Religion, Alter, Hautfarbe, Rasse, sexueller Orientierung, Nationalität oder Behinderung. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10065716 Oct 30, 2025 Switzerland Summary Job Description Summary In dieser Rolle übernehmen Sie die technische und wissenschaftliche Verantwortung für prozessspezifische Fragestellungen innerhalb der Produktion. Sie stellen sicher, dass alle Prozesse termingerecht und gemäß cGMP, SOPs sowie geltenden Richtlinien und Standards (z.-B. HSE, NOSSCE) durchgeführt werden. Darüber hinaus tragen Sie zur kontinuierlichen Verbesserung der Qualität und Effizienz bei und sichern die Geschäftskontinuität durch Ihre Expertise und Problemlösungskompetenz. #LI-Onsite Location: Muttenz, Switzerland About the Role hr Aufgabenbereich: Unterstützung der Produktion bei technischen und prozessspezifischen Herausforderungen in Echtzeit Sicherstellung der GMP-konformen Durchführung und Dokumentation aller Produktionsprozesse Durchführung und Pflege von Validierungen sowie relevanter Produktionsdokumente Schulung und Weiterentwicklung der Produktionsmitarbeitenden Bearbeitung von Abweichungen, Beschwerden und Umsetzung von CAPAs Mitwirkung bei Inspektionen und Einhaltung gesetzlicher Qualitäts- und HSE-Vorgaben Leitung und Unterstützung von Projekten zur kontinuierlichen Verbesserung und Technologieübertragung Definition technischer Anforderungen und Begleitung von Investitionsprojekten Förderung der Qualitäts- und HSE-Kultur am Standort Ihr Anfoderungsprofil: MSc oder PhD in organischer Chemie Mindestens zwei Jahre Erfahrung in der pharmazeutischen Industrie und in der Produktion Sehr gute Deutsch- und Englischkenntnisse Optional: Erfahrung mit Oligonukleotiden (z.-B. siRNA) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive working environment and diverse teams, representative of the patients and communities we serve. Accessibility and accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Job Description Summary In dieser Rolle übernehmen Sie die technische und wissenschaftliche Verantwortung für prozessspezifische Fragestellungen innerhalb der Produktion. Sie stellen sicher, dass alle Prozesse termingerecht und gemäß cGMP, SOPs sowie geltenden Richtlinien und Standards (z.B. HSE, NOSSCE) durchgeführt werden. Darüber hinaus tragen Sie zur kontinuierlichen Verbesserung der Qualität und Effizienz bei und sichern die Geschäftskontinuität durch Ihre Expertise und Problemlösungskompetenz. #LI-Onsite Location: Muttenz, Switzerland About the Role hr Aufgabenbereich: Unterstützung der Produktion bei technischen und prozessspezifischen Herausforderungen in Echtzeit Sicherstellung der GMP-konformen Durchführung und Dokumentation aller Produktionsprozesse Durchführung und Pflege von Validierungen sowie relevanter Produktionsdokumente Schulung und Weiterentwicklung der Produktionsmitarbeitenden Bearbeitung von Abweichungen, Beschwerden und Umsetzung von CAPAs Mitwirkung bei Inspektionen und Einhaltung gesetzlicher Qualitäts- und HSE-Vorgaben Leitung und Unterstützung von Projekten zur kontinuierlichen Verbesserung und Technologieübertragung Definition technischer Anforderungen und Begleitung von Investitionsprojekten Förderung der Qualitäts- und HSE-Kultur am Standort Ihr Anfoderungsprofil: MSc oder PhD in organischer Chemie Mindestens zwei Jahre Erfahrung in der pharmazeutischen Industrie und in der Produktion Sehr gute Deutsch- und Englischkenntnisse Optional: Erfahrung mit Oligonukleotiden (z.B. siRNA) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive working environment and diverse teams, representative of the patients and communities we serve. Accessibility and accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards