Novartis AG

Summary Linienführer:in Primärverpackung – Feste Darreichungsformen Für unser Team in der Primärverpackung fester Darreichungsformen suchen wir per sofort eine:n motivierte:n und erfahrene:n Linienführer:in mit fundierten GMP-Kenntnissen, ausgeprägtem technischem Verständnis und Teamgeist. In dieser Funktion sind Sie verantwortlich für die termingerechte Ausführung der Ihnen zugewiesenen Herstellungs- und Verpackungsaufgaben gemäß Produktionsplan unter Einhaltung aller GMP-, Sicherheits- und Umweltrichtlinien. About the Role Hauptaufgaben Maschinelles Verpacken von Arzneimitteln (Flaschen und Blister) an modernen, komplexen Verpackungsanlage Führen, Einteilen und Unterstützen des Anlagenteams der zugewiesenen Produktionslinie Umrüsten/ Einrichten und Anfahre/Betreiben der Produktionsanlagen Verantwortung für die Anlagenreinigung und Desinfektion Durchführung von In-Process-Control (IPC)-Kontrollen Auftragsvorbereitung in Zusammenarbeit mit Planung, Lager und Prozessexpert:innen Beheben kleiner technischer Störungen; Unterstützung bei Qualifizierungs- und Instandhaltungsarbeiten nach Bedarf Einarbeitung neuer Mitarbeitender im Bereich Korrekte, vollständige und nachvollziehbare Dokumentation der Tätigkeiten auf Papier und in der elektronischen Chargendokumentation (z. B. SAP) gemäß GMP Fachansprechpartner:in für die zugewiesenen Anlagen und Prozesse bei Audits und Inspektionen Sicherstellung und Durchsetzung von GMP- und HSE-Vorgaben Mitwirkung am Housekeeping (Ordnung, Sauberkeit, 5S) im Produktionsbereich Kontinuierliche Verbesserung: Identifikation von Schwachstellen und Vorschlag von Maßnahmen (Organisation, Prozess, Sicherheit, Hygiene) Teilnahme an allen funktionsrelevanten Schulungen und Sicherstellung des geforderten Trainingsstandes Bereitschaft zu Mehrarbeit bzw. Schichtarbeit (Früh- und Spätschicht), sofern erforderlich Zusammenarbeit mit anderen Einheiten und Einsatz in angrenzenden Bereichen bei Bedarf (z. B. weitere Primärverpackungslinien, Lager, Sekundärverpackung, Manuelle Handverpackung) Erforderliche Fähigkeiten Abgeschlossene Ausbildung im Bereich Chemie / Pharma oder Technik Berufserfahrung als Linienführer:in/Linienleiter:in im GMP-regulierten Umfeld, idealerweise in der Verpackung pharmazeutischer Produkte (Flaschen und Blister)Ausgeprägte technische Kompetenz mit Erfahrung im Einrichten, Bedienen und Störungsbeheben an automatisierten Produktionsanlagen Hohes Pflicht- und Qualitätsbewusstsein; sorgfältige Dokumentations- und Arbeitsweise sowie Ordnung und Sauberkeit am Arbeitsplatz Konstruktiv, lösungsorientiert, verantwortungsbewusst; tiefes Verständnis für Qualität und Compliance Hohe Selbstmotivation und schnelle Auffassungsgabe zur Einarbeitung in neue Tätigkeiten Erfahrung in der Führung kleiner Teams und in der Mitarbeitendenausbildung von Vorteil Gute IT- sowie MS-Office-Kenntnisse (z. B. Erstellung einfacher Arbeits- oder Bedienungsanweisungen) Fundierte Kenntnisse im GMP-Umfeld und in hygienekritischen Bereichen Organisationstalent und Durchsetzungsvermögen Sehr gute Deutschkenntnisse in Wort und Schrift; Englischkenntnisse von Vorteil Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: We are searching for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Main Accountabilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g. xRNAs) In your role, you will be leading an analytical subteam and preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaborate with internal and external stakeholders of drug development and coaching of analytical experts. You lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership ​ Ideal Background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years’ experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus Proven knowledge in Early or late phase parenteral development and filing Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. High level and intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is a key element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Excellent communication and role model skills Good understating on how to use novel digital tools to become more productive in a global project management environment. Fluent in English (oral and writing), German is a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis has embraced a bold strategy to drive a company-wide digital transformation. Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that foster innovative approaches to hasten drug discovery and development. By utilizing both internal and external Research & Development data with the power of data science, predictive models, generative AI, and machine learning, our objective is to identify new targets, create more effective therapeutic molecules, better predict drug pharmacokinetics and safety risks, refine clinical trial design, and significantly shorten development cycles. The Artificial Intelligence & Computational Sciences (AICS) team leads Biomedical Research (BR) in exploring and applying advanced AI and ML methodologies to generate novel drug discovery insights, and to speed and improve drug discovery efficiency whilst focusing on patients’ needs. AICS partners with drug discovery teams, raises the level of AI expertise across BR and ensures that BR science keeps up with the rapidly evolving ecosystem of AI technologies by connecting with AI leaders in academia and industry. This rolewithintheAI Methodsgroup of AICS will be tasked with critical assessment of the model landscape, identifying opportunities for methodological innovation, and building the right AI approaches, algorithms, models and workflows to maximize impact on key domains areas of biomedical research that will potentially lead to developing better drugs, faster. About the Role Responsibilities: Work with a team of AI researchers, data scientists and SMEs with core domain expertise to develop and deliver focused, robust, performant AI algorithms and solutions to accelerate drug discovery. Stay informed about the latest AI methods, increase understanding of the problem domain, and ask detailed questions to identify potential areas for innovation in AI across the drug discovery pipeline. Promote awareness of advancements in AI methods for addressing key research questions within biomedical research. Fluently adopt Engineering and Product Development resources to ensure the adoption of AI solutions . Help position AI-aided drug discovery contributions to deliver and support progress of BR’s portfolio, enable new kinds of therapeutic discoveries, shorten cycle times, and increase efficiency. Collaboration & partnership A respectful, team-player attitude is an absolute must. Regularly communicate, engage, align with AICS teams, broader data science community, and senior scientists. Initiate and lead key high-value internal collaborations across BR. Help design translatable metrics for AI models that will lead to tangible impact in collaboration with BR DAs and FAs. Collaborate cross-functionally to translate model outputs into actionable hypotheses and guide experimental design. What you’ll bring to the role: 4+ years of significant experience in innovation, development, deployment and continuous support of Machine Learning and modeling. Strong hands-on coding proficiency in Python and deep learning frameworks and an expertise in bringing advanced analytics insights and actions to a large r esearch organization Wide exposure to representation learning, deep generative modeling, probabilistic reasoning, and explainability approaches. with a deep passion for understanding and explaining the technical concepts underlying ML approaches. Strong understanding and experience in using version control systems for developing software (e.g. GitHub, git, subversion, bitbucket, etc.) with expertise in large-scale model training, distributed computation, and foundation model adaptation. Publications, patents, or open-source contributions that demonstrate machine learning innovation and expertise, with passion for understanding emerging technologies and how they can integrate into business solutions Ability to balance requirements, manage expectations, and drive effective results using a proactive can-do attitude towards identifying and resolving issues, as well as a proven ability to work exceptionally well within complex matrixed teams. A deep curiosity and passion for biomedical sciences driven therapeutic discovery. Nice to have: Experience with applying ML to one or more functional areas of core drug discovery like target identification, computational chemistry, protein structure modelling and design or translational medicine is a plus. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Relevant areas of desired expertise: Transformer architectures (Text, Vision, DNA/amino-acid sequences, Gene expression vectors);Long-context transformersandefficient attention mechanisms; diffusion models;flow matching;energy-based models; multimodal architectures; graph neural networks; geometric deep learning; Bayesian optimization; Reinforcement learning; Active learning; Variational Inference; Self-supervised learning; Contrastive learning; Domain adaption; Test-time adaptation Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: At Novartis, we are reimagining medicine to improve and extend people's lives. We discover and develop breakthrough treatments and find new ways to bring cures to as many people as possible. Without safe, easy-to-use, high-quality drug delivery devices our patients could not get their medicines. This is where you come in; the Device Technology Solution Center is looking for a Senior Design Engineer for the development of drug device combination products. The aim is to develop a new Auto-injector platform from early phase development to market launch. About the Role Your Responsibilities: Your responsibilities include, but are not limited to: Work on Platform development and participate to project activities in cross-functional teams for easy-to-use, safe and robust products Participate to the complete development process of medical devices (ideation, brainstorming, prototyping, piloting and transfer to manufacturing) Create and review IP Create, manage and maintain CAD, 3D and drawings Create, manage and maintain Tolerance Analysis Size and specify plastic and metallic components Work with third party suppliers, including prototyper, tool makers, CMOs Manage testing and characterization for acceptance, compliance, performance etc., and suggest improvements Perform root cause analysis and develop robust solutions to prevent re-occurrence Ensure components are delivered and controlled to the required quality for clinical trials and commercial production Write key design history file documents: design input requirements, component specifications and design verification documents. Ensure device design development is delivered to a high quality Role Requirements Degree in mechanical engineering or equivalent Preferably 3 years of experience in medical device development Proficient spoken communication and excellent technical writing skills in English Experience in designing plastic and metal components; tolerance analysis; metrology; lab testing Experience in material qualification Good knowledge in design for manufacturing and assembly Good knowledge in key regulations and standards (e.g. ISO23098, ISO 11608, ISO 10993, MDR, Design Controls) Design History File documentation Ability to interact with cross functional team in matrix organization Minimum 80% on site work – 4 days/week Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: At Novartis, we are reimagining medicine to improve and extend people's lives. We discover and develop breakthrough treatments and find new ways to bring cures to as many people as possible. Without safe, easy-to-use, high-quality drug delivery systems our patients could not get their medicines. This is where you come in; the Device Technology Solution Center needs you as Senior Expert Engineering for the development of drug device combination products working alongside our talented, bright and diverse teams. Our Device Technology Solution Center drives the technical development of auto-injectors as well as novel drug delivery principles, e.g. drug delivery to the brain or radioligand therapy. We closely collaborate with project management, human factors engineers, packaging experts, analytical testing, production, external partners, regulatory experts and many more. The aim is to develop and/or integrate innovative drug delivery systems with drug formulation and author state-of-the-art technical documentation for health authorities and production. About the Role Your Responsibilities: Your responsibilities include, but are not limited to: Develop platforms and collaborate with cross-functional teams to deliver safe, user-friendly, and reliable products Lead and support teams in the field of assembly for parts/device, design equipment and process across from prototyping to commercial scale Create and maintain relevant Design History File (DHF) documents, ensuring high-quality device design and development Contribute to all phases of medical device development: ideation, prototyping, piloting, and manufacturing transfer Ensure components meet quality standards for clinical trials and commercial production Collaborate with external partners, including prototypers, toolmakers, and CMOs Identify root causes of issues, define and implement robust solutions Role Requirements Degree in mechanical engineering or equivalent Preferably 5 years of experience in medical device development Proficient spoken communication and excellent technical writing skills in English Proven experience in assembly of plastic and metal components / sub-assemblies Proven experience in design for manufacturing and design for assembly Good knowledge in key regulations and standards (e.g. ISO 13485, ISO 23908, ISO 11608, ISO 10993, MDR, Design Controls) Ability to interact with cross functional team in matrix organization Minimum 80% on site work – 4 days/week Travels to visit suppliers and CMOs Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary ~ Bieten Sie Qualitätssicherung und Compliance-Aufsicht für Entwicklungs- und Forschungsfunktionen. Fördern Sie die Überwachung von Qualitätsmanagementsystemen und -initiativen innerhalb der globalen, regionalen und Länderorganisation und stellen Sie die Einhaltung der geltenden regulatorischen Anforderungen der Gesundheitsbehörden (z. B. GCP, GLP, GMP, PV, IP) und der Novartis-Verfahren und Qualitätsstandards sicher. Vorbild für gutes Qualitätsverhalten bei gleichzeitiger Förderung einer Qualitätskultur (z. B. richtiges erstes Mal usw.), um die nicht-qualitativ hochwertigen Stakeholder (z. B. NIBR, GDD) positiv zu beeinflussen. Entwickeln, vorantreiben und/oder unterstützen Sie Qualitätsplaninitiativen, um Die Organisationsstrategie, Mission und Vision zu erreichen. About the Role Key Responsibilities: Proactively provide QA leadership to the business strategy for assigned programs/trials by ensuring considerable organization awareness (e.g. Interrelationship of departments and business priorities), Drive implementation of quality strategy within Global Clinical Team (GCT )/ Clinical Trial Team (CTT) under responsibility Regularly monitor the implementation of the annual Quality Plan pertaining to the assigned programs/studies Ensure adequate oversight of proactive quality risk management process in the overseen areas including quality risk assessments and submission/inspection readiness activities and ensure that Clinical Trial Process (CTP) are in control Provide robust and clear quality oversight in the following areas of clinical development: Support/collaborate with key stakeholders (e.g., Country Development Quality (CDQ), Development Units (DUs), GCT and/or CTT members) to ensure that risks are detected and remediated. Support core governance for quality incident management for critical and major deviations pertinent to the programs being assigned and ensure timely escalation when required. Provide Good Clinical Practice (GCP) guidance to day-to-day questions arising from Clinical trials deliverables. Collaborate with Country Development QA and External Service Providers (ESP) QA to drive initiatives relevant to internal monitoring and outsourced activities Quality oversight. Support inspections preparation and facilitation in collaboration with other QA groups within Research & Development Quality (RDQ). Support audits and inspections follow-up activities including Corrective & preventative Actions (CAPA) preparation. Actively leverage audit/inspection outcomes/trends to sustain improvement in clinical trials conduct. Active participation in continuous improvement initiatives (including Work streams) and ensure that areas identified as weaknesses are properly being addressed and executed for sustainability Be QA point of contact for the defined trials and attend the meetings and ensure quality is embedded in the decision taking processes. Essential Requirements: Bachelor’s degree in life science or healthcare field required. Advanced degree or equivalent education/degree in life sciences/healthcare preferred (PhD/MD/ PharmD/ Masters). 7 years of involvement in regulated activities (GCP/ Pharmacovigilance (PV)), clinical development and/or QA positions. Broad understanding of global expectations of Health Authorities in the area of Clinical Development and profound understanding of the science of product development. Ability to work independently and in a global/matrix environment. 3 or more years’ experience in managing projects. Strong skills in GCP, quality and/or clinical development Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you passionate about how innovative engineering shapes the future of healthcare? Join our Device Development team at Novartis in Basel and play a key role in delivering life-changing therapies to patients worldwide. Drug delivery devices are essential to ensure that patients receive their medicines safely, effectively, and with ease—and this is where you come in. As a Mechanical Engineering Intern, you will gain hands-on experience in the development and characterization of components for one of our flagship medical devices. Working alongside experienced mentors, you’ll validate theoretical assumptions, explore material and process design, and contribute to innovative solutions that impact patient care. About the Role Location: Basel, Switzerland; #LI-Hybrid (Fridays remote) This internship is for 6 to 12 months and offers the opportunity to start immediately. Please note that we can only accept applicants who are eligible to work in Switzerland. Key Responsibilities: CT scan & Tolerance Analysis: Perform dimensional checks and confirm theoretical assumptions using CT scanning technology. Analyze tolerance stack-ups to ensure compliance with design specifications. Power Spring Development: Support material selection and process definition for power spring components. Collaborate on prototype testing and performance evaluation. Medical Device Characterization: Characterize assembly performance of plastic components and sub-assemblies. Document findings and provide recommendations for design improvements. Essential Requirements: Currently pursuing or recently completed a Bachelor’s or Master’s degree in Mechanical Engineering. Experience with medical devices is a strong plus. Fluent in English is a must; knowledge of French or German is an advantage. Strong analytical skills and attention to detail. Ability to work independently and in a collaborative team environment. Desirable Requirements: Familiarity with tolerance analysis and mechanical testing is desirable. CAD knowledge (e.g., SolidWorks) is a plus. Benefits and Rewards: Exposure to cutting-edge medical device development. Mentorship from experienced engineers in a dynamic, innovative environment. Opportunity to contribute to projects that impact patient safety and product performance. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, color, race, sexual orientation, nationality or disability. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Application deadline: January 21 EOB. Please submit a cover letter that includes your motivation for the position and from when you will be available. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10068737 Dec 17, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite Join our xRNA Team in Biomedical Research in Basel and help shape the future of RNA therapeutics. We are developing the next-generation siRNA medicines with the ambition to transform the lives of patients with unmet medical needs. This is an opportunity to bring your scientific talent and curiosity into a highly collaborative, innovation-driven environment where your work will directly impact the discovery and development of breakthrough therapies. We are looking for a lab-based Senior Scientist who thrives in high-energy teams, loves solving challenging problems, and has a strong background in biological research and RNA biochemistry. If you-re passionate about developing and optimizing methods, workflows, and best practices that advance siRNA discovery, we want you on our team. About the Role Key Responsibilities Independently design, plan and execute siRNA screening experiments using mammalian and primary cell culture, including cell-based transfection assays, qPCR and reporter-based readouts. Develop, optimize and validate novel biochemical and cell-based assays to support siRNA discovery and optimization. Contribute to automated workflows using liquid-handling robotics platforms (e.g. for assay miniaturization, screening and sample preparation). Drive continuous improvement in lab organization, workflows, equipment implementation and adoption of new technologies. Collaborate effectively with an interdisciplinary team in a matrix environment, and present data and conclusions clearly in both verbal and written form. Maintain high-quality records in electronic lab notebooks; analyze, interpret, and report results in a timely manner. Minimum Requirements MS or a Bachelors/scientific apprenticeship with at least 5+ years of industry experience or recent graduate PhD with 0-1 years of industry experience in biochemistry, cell biology or related fields. Ideally a minimum of 3-5 years of laboratory research experience in a pharma and/or biotech industry setting. Strong hands-on experience in cell and molecular biology techniques, including: Mammalian and primary cell culture mRNA and protein isolation, characterization and quantification (e.g. familiarity and working knowledge of likes of qPCR, CLIP , IP (Immuno Precipitation), ELISA, Western blot) next-generation sequencing workflows (e.g. NGS library preparation) Experience with liquid-handling systems and automation of cell-based assays or a strong interest in developing such is a plus. Proven ability to troubleshoot and refine assays to improve sensitivity, robustness, reproducibility and throughput. Strong competence in MS Office applications (Excel, Word, Teams), electronic lab notebooks, and data analysis software (e.g. GraphPad Prism, Spotfire). Excellent organizational skills, attention to detail, and strong verbal and written communication skills. Ability to collaborate and thrive in a fast-paced, team-oriented research environment. Desirable Requirements Familiarity with primary cell culture models (e.g. primary human or rodent cells). Exposure to bioinformatics and coding (e.g. R and/or Python) for data processing, visualization and analysis. Experience with specific automation platforms (e.g. BioMek, Opentrons) is a strong plus. Additional Information *Restrictions on flexible working may apply and are discretionary; these can be discussed during the interview process, where applicable. Accessibility and Accommodation Novartis is committed to working with, and providing reasonable accommodation to, all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or if you would like more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Play Play 00:00 Play Seek 10 seconds backwards Seek 10 seconds forward 00:00 / 01:54 Unmute Click to volume controlUse the arrows to control the volume Settings Turn on Picture in picture Show Full screen VIDEO Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Research & Development Biomedical Research Switzerland Job ID REQ-10068737 Senior Scientist - xRNA /sIRNA Discovery (80-100%*) Apply to Job (link is external)

Job ID REQ-10068389 Dec 11, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: We are searching for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Main Accountabilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g. xRNAs) In your role, you will be leading an analytical subteam and preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaborate with internal and external stakeholders of drug development and coaching of analytical experts. You lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership Ideal Background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years- experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus Proven knowledge in Early or late phase parenteral development and filing Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. High level and intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is a key element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Excellent communication and role model skills Good understating on how to use novel digital tools to become more productive in a global project management environment. Fluent in English (oral and writing), German is a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Development Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Research & Development Development Switzerland Job ID REQ-10068389 Analytical Project Leader (m/f/d) Apply to Job (link is external)

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite Join our xRNA Team in Biomedical Research in Basel and help shape the future of RNA therapeutics. We are developing the next-generation siRNA medicines with the ambition to transform the lives of patients with unmet medical needs. This is an opportunity to bring your scientific talent and curiosity into a highly collaborative, innovation-driven environment where your work will directly impact the discovery and development of breakthrough therapies. We are looking for a lab-based Senior Scientist who thrives in high-energy teams, loves solving challenging problems, and has a strong background in biological research and RNA biochemistry. If you’re passionate about developing and optimizing methods, workflows, and best practices that advance siRNA discovery, we want you on our team. About the Role Key Responsibilities Independently design, plan and execute siRNA screening experiments using mammalian and primary cell culture, including cell-based transfection assays, qPCR and reporter-based readouts. Develop, optimize and validate novel biochemical and cell-based assays to support siRNA discovery and optimization. Contribute to automated workflows using liquid-handling robotics platforms (e.g. for assay miniaturization, screening and sample preparation). Drive continuous improvement in lab organization, workflows, equipment implementation and adoption of new technologies. Collaborate effectively with an interdisciplinary team in a matrix environment, and present data and conclusions clearly in both verbal and written form. Maintain high-quality records in electronic lab notebooks; analyze, interpret, and report results in a timely manner. Minimum Requirements MS or a Bachelors/scientific apprenticeship with at least 5+ years of industry experience or recent graduate PhD with 0-1 years of industry experience in biochemistry, cell biology or related fields. Ideally a minimum of 3-5 years of laboratory research experience in a pharma and/or biotech industry setting. Strong hands-on experience in cell and molecular biology techniques, including: Mammalian and primary cell culture mRNA and protein isolation, characterization and quantification (e.g. familiarity and working knowledge of likes of qPCR, CLIP , IP (Immuno Precipitation), ELISA, Western blot) next-generation sequencing workflows (e.g. NGS library preparation) Experience with liquid-handling systems and automation of cell-based assays or a strong interest in developing such is a plus. Proven ability to troubleshoot and refine assays to improve sensitivity, robustness, reproducibility and throughput. Strong competence in MS Office applications (Excel, Word, Teams), electronic lab notebooks, and data analysis software (e.g. GraphPad Prism, Spotfire). Excellent organizational skills, attention to detail, and strong verbal and written communication skills. Ability to collaborate and thrive in a fast-paced, team-oriented research environment. Desirable Requirements Familiarity with primary cell culture models (e.g. primary human or rodent cells). Exposure to bioinformatics and coding (e.g. R and/or Python) for data processing, visualization and analysis. Experience with specific automation platforms (e.g. BioMek, Opentrons) is a strong plus. Additional Information *Restrictions on flexible working may apply and are discretionary; these can be discussed during the interview process, where applicable. Accessibility and Accommodation Novartis is committed to working with, and providing reasonable accommodation to, all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or if you would like more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: The Technical Project Leader (TPL) formulates and drives a scientifically sound and business driven technical project strategy for Technical Research & Development (TRD), including financial planning, risk assessments and contingency planning as appropriate and in line with the overall Research & Development Project Team strategy and TRD objectives. The TPL will lead the TRD-development of Mixed Modality, Small Molecule and/or Biologics projects as well as leading, representing, managing, and supporting the CMC team, ensuring alignment with other departments and functions inside and outside of TRD as well as third parties as appropriate About the Role Strategy Establishes technical development plans in line with priority classification of project, gated by clinical readouts as appropriate and with an enterprise view in consideration of overall portfolio priorities. Establishes high level summaries for presentation to management and stakeholders. Has advanced skill to identify, assess, manage, and communicate CMC risks / program risks. Due to seniority and experience, can handle more difficult risks, issues in more complex projects and handle multiple risks of DS/DP/Device even with junior CMC team members. Provides drug development expertise in addition to technical expertise. Follows standard process but at the same time thinks outside the box based on existing knowledge. Challenges the status quo, is curious and fosters creativity of team members and own creativity. Leverages existing knowledge and implements in the overall Global Project Team project strategy. Continues to follow and stands behind Global Project Team decisions. For complex late phase programs, supports Senior TPL for defined work packages. Interfaces Participates in boards and joins and/or can lead discussions in leadership teams. Is highly skilled in collaborative settings (i.e., external vs internal, CROs, DDs, in-/out-licensing settings). Approaches/analyses issues and collaborates with other line functions for optimal solutions. Takes into account multiple stakeholder perspectives and approaches to find optimal solutions and build commitment and consensus. Provides knowledge of industry, main competitors, customers and external environment – this includes healthcare industry and global industry, digital and technological advancements. Shares knowledge with CMC community, e.g., by lessons learned sessions. Uses knowledge and experience to challenge and influence CMC line functions and/or Global Project Team in background of the overall drug development strategy / industry insight. Actively contributes to Global Project Team beyond CMC line functions. Is able to navigate and manage the complexity of the disease area GPTs. Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. People Learns to manage teams/stakeholders appropriately (utilizing their support). Brings forward sound proposals and shares lessons learned, without passing the blame. Anticipates setbacks and stays in control – takes criticism as intended for situations (not personally or toward particular individuals). Recovers quickly from problems and setbacks. Exhibits servant leadership and provides mentoring/coaching to junior TPLs, line functions and CMC team members to support their professional and personal growth. Leads by example and drives decisions. Generic Activities Leads CMC teams (in a matrix set up). Leads CMC team and other meetings (agendas, minutes, action tracker, moderation). Acts as link and conveys CMC topics between Global Project Team, CMC line functions and CMC boards to support decision making. Sets the CMC team and sub-teams objectives in line with the GPT / PoC Team objectives. Communicates transparently. Is able to communicate and adjust the message based on the audience (i.e., level of technical detail, etc.). Has financial and resource oversight, budget accountability/oversight. Takes responsibility for successes and failures of own and team's work, holds self and team accountable for outcomes (shifts priorities to ensure success). Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. Ideal Background Education (minimum/desirable): Advanced degree in life science, engineering or equivalent. Languages: Fluent in English Experience/Professional requirement: Successfully demonstrated several years (minimum of 2-3 years) of directly related experience as functional project leader and relevant experience as Associate TPL or equivalent. Has strong scientific/technical knowledge & understands technical development tasks for Small Molecules or Biologics (minimum) and Mixed Modalities (ideal). Is able to establish/maintain DS/DP/Device supply plan (in alignment with the clinical supply project lead). Has fundamental knowledge of GMP and regulatory requirements. Has a solid cross-functional knowledge (PK/PD, tox, clinical, commercial) regarding drug development. Manages end to end technical drug development and knowledge. Completed basic project management training. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As part of International HEOR & PCO in International Value & Access, the Patient Centered Outcomes (PCO) HTA, TA Director within the HEOR TA teams, in partnership with HEOR leads co-leads the PCO reimbursement strategy that enables measurements of patient centered outcomes to support robust payer value propositions and evidence for HTAs, optimizing international access for prioritized Novartis assets. The PCO HTA TA Director will oversee one therapeutic area (e.g., CRM, immunology, oncology, or neurosciences) and their responsibility will span multiple assets/indications. Support and guidance to other members of the HEOR TA team for input or development of plans e.g. Health Technology Assessment Strategy Plans, Integrated Evidence Plans. The PCO HTA TA Director will be leading the HEOR Patient Centered Outcomes strategy within a Therapeutic Area and will contribute to the OnePCO Strategy through direct interface with the Clinical Development PCO Center of Excellence (PCO COE) when novel or disease-specific PCOs are required. In collaboration with regions and countries, The PCO HTA TA Director ensures that local PCO requirements are integrated into the PCO reimbursement strategy, and in the global and international evidence plans and PCO activities. Focus will be given to providing clear strategic rationale for and selection of health utility and other PROs for differentiation and translation to economic impact in partnership with HEOR. In addition, support the implementation of country-specific PCO evidence generation as needed to support access. The Director, HEOR PCO, will serve as an internal expert on health utility assessment activities. She/he will also lead health state valuation projects via development and management of Time Trade-Off (TTO) or Standard Gamble (SG) studies where appropriate. The PCO HTA TA Director will support HEOR TA on early scientific advice with HTAs e.g. EU HTA JSC and attend HTA meetings and/or support negotiations in collaboration with cross-functional and country team members. The Director will cultivate a strong partnership with team members from internal groups incl. Access, Clinical Development, PCO COE, AQS Biostat, Medical Affairs, and the International Commercial organization. In addition, PCO HTA TA Director will represent Novartis externally and ensure thought leadership in collaboration with external partners (e.g. industry consortiums e.g., ISPOR, ISOQOL, PRO/Utility experts). Internally, the Director ensures within HEOR TA and Novartis to drive understanding of HTA requirements for PCO, health utility assessment, and adoption of standards and best practices. About the Role Key Responsibilities: Co-leads with the HEOR TA lead the development, delivery and communication of a compelling PCO reimbursement strategy within the HTAP (Health Technology Assessment Strategy Plan), IPAS (Integrated Product Access Strategy), 1BP (One Brand Plan) and aligned with Integrated Evidence Plan (IEP). In partnership with the PCO COE, Global Program Teams, HEOR Leads, HTA Evidence Synthesis, Access, Medical Affairs, and AQS Biostat, ensures that the PCO measurement strategy includes patient reported outcomes and health utilities of relevance for international HTAs and payers into clinical development program. Participates in and co-leads projects on behalf of the OnePCO Alignment Forum to ensure PCOs critical for HTAs and payers are included in in clinical trials, non-interventional studies and real-world studies for select assets and coordinates with countries to ensure alignment on local HTA and payer needs. Drive understanding of HTA requirements for PCO, health utility assessment, and adoption of standards and best practices by key markets. Leads health state valuation projects via development and management of Time Trade-Off (TTO) or Standard Gamble (SG) studies where appropriate. Assists in scientific discussions with HTA agencies, particularly scientific advice from e.g. EU HTA JSC, NICE, CADTH…for PRO/PCO endpoints, MCIDs, and by preparing appropriate briefing documents and dossier by ensuring robust patient value proposition is included. Develops strategic scientific communication plan incl. submission and presentation of research in peer-reviewed journals and scientific/methodological congresses. Engages with external thought leaders, identify research collaboration/partnerships and represent Novartis with external stakeholders (academic institutions, HTA agencies…) to monitor and shape the external environment with respect to patient centred outcomes research and evolving evidentiary standards for utility endpoints and ensures awareness of these changes for Novartis. Lead above-brand research projects/initiatives to pilot innovative methodologies for value demonstration and elevate internal standards/best practices within International Value and Access and at Novartis with cross-functional partners. Essential requirements: 8+ years of Pharma Industry experience with 5+ years of experience in HEOR roles in pharmaceutical companies or consulting, with at least 3 years demonstrating specific leadership of health utility projects Advanced Degree in relevant field Experience in evaluating, developing and validating PRO/PCO instruments to meet HTA reimbursement requirements In-depth understanding of key patient centered outcomes measurement systems – e.g., EuroQoL, Quality Metric Short-Form measures, HUI etc. Ability to lead in a cross functional environment Ability to manage multiple priorities in rapidly changing environment Ability to work collaboratively to leverage other HEOR capabilities (strategy, regions, countries, COE PCO) Desirable requirements: Ph.D., M.D., MBA, MSc or equivalent. Strong external interfaces and network: KOLs, clinical research & scientific groups, payers, and policy organizations Experience in conducting and evaluating PCO measures from conceptualization through negotiation with international health authorities. Experience in HTA submissions Location: This role can be based in the UK, London but also in Dublin, Ireland or Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: Act as Isotope Project Lead (IPL) by providing the specialist knowledge and expertise as Subject Matter Expert (SME) of radioisotope production and purification with particular focus on assessing, developing, and optimizing new technologies that support RLT products Life Cycle Management (LCM). Develop, optimize and transfer radioisotopes production and purification/separation processes. This is done in close collaboration with the relevant development centers, and Contract Manufacturing Organizations (CMOs). About the Role Major accountabilities: Manage inter functional project plan and budget using the Project Planning tool or System Identify issues and potential bottlenecks within projects and proposes options Contribute to the Radioisotope TRD-related activities. Ensure constant technological survey on the field of radioisotopes production. Apply scientific/technical expertise to identify new programs of interest for the company and support their development from early evaluation up late phase supply. Participate to development programs and activities around isotopes in adherence with global Isotope strategy and objectives within agreed timelines and budget, timely report key advancements and challenges. Identify strategic external partners for the activation of research collaboration agreement to develop new production technologies/ access to innovative isotopes. Implements strategic policies when selecting methods, techniques, and evaluation criteria for obtaining results. Establishes and assures adherence to budgets, schedules, work plans, and performance requirements. Represents area as core member in the Global Project Teams for defining global scientific strategy for development up to submission and approval in major markets of assigned product(s). Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable) Minimum Requirements: BSc. in Chemical Engineering, Pharmaceutical Technology, or equivalent scientific degree. Desirable MSc., PhD or equivalent experience. Desirable degree in Radiochemistry and strong scientific knowledge in nuclear medicine Successfully demonstrated several years (minimum of 5 years) of directly related experience in a scientific area or Ph.D. or equivalent Proven Project Leadership in all project phases Proven process understanding (Pharma, GMP, Validation and Regulatory aspects). Sound experience of data handling and applied statistics is a must. Strong understanding of risk assessment and risk management fundamentals/tools Quality-oriented with attention to detail Excellent verbal and written communication skills Excellent problem solving and decision-making skills Defining and implementing productivity improvement measures. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are seeking a highly motivated and experienced human geneticist. This role requires strong strategic and leadership skills, as well as expertise in genetics with a proven ability to identify the causal drivers of disease. You will be adept at leveraging these approaches within an interdisciplinary team to foster innovation and discover novel targets. As the site lead for Basel, you will have the opportunity to directly and indirectly lead a small team. This position is part of the Human Genetics & Targets group within the Discovery Sciences (DSc) department in Biomedical Research (BR) at Novartis. The DSc Human Genetics & Targets team is a global group of computational and experimental scientists dedicated to validating or invalidating genetics-driven target hypotheses. The team's extensive expertise in genetics analytics, biology, and translatable models is enhanced by DSc's capabilities in AI, functional genomics, chemical biology, and more. The team collaborates with disease area specialists to not only identify disease associations but also to understand the underlying disease mechanisms and advance drug discovery projects to benefit patients in need. About the Role Your responsibilities will include, but are not limited to: Leading a small team and working within a larger genetics computational group to plan, develop, and implement human genetic strategies for drug discovery projects in alignment with department and company goals Work with interdisciplinary project teams across a variety of disease areas to deliver (fit-for-purpose) human genetics analyses for drug discovery impact Guiding the use of population scale biobanks and serving as a champion for a human genetic cohort Coaching and mentoring the next generation of genetics experts Bringing scientific curiosity and enthusiasm to make discoveries in a collaborative and team-focused environment Engaging as an insightful and proactive member of the DSc Human Genetics Data Science team to shape the strategic direction of the team and broader BR genetics efforts What you’ll bring to the role: PhD with 7+ years of post-graduate work or equivalent experience in genetics Experience analyzing and interpreting human genetics data is a must Extensive experience with the management and analysis of large biobank data is a must and experience of multiple biobanks is preferred. Strong leadership skills and experience leading computational scientists Drug discovery experience in an industry stetting is encouraged but not required Experience with additional ‘omics data (RNA sequencing, epigenetics, proteomics) and NGS data A curiosity for emerging technologies and methods Exceptional collaboration, communication and problem-solving skills, learning agility, and an interest in engaging with peers for the design and implementation of new ideas A strong publication record Fluency in Python, R, SQL and/or other relevant programming languages Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve ​ Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: We are seeking a highly motivated and experienced PhD-level scientist to lead our mid/large xRNA synthesis team in Basel. This position requires extensive collaboration within a multidisciplinary environment, bridging research and development to discover and advance innovative siRNA therapies addressing significant unmet medical needs. About the Role Key Responsibilities Oversee a state-of-the-art oligonucleotide synthesis facility, managing both capital and consumables budgets efficiently. Lead and guide a team of scientists specializing in oligonucleotide synthesis and purification of oligonucleotides at millimole scale to deliver on our growing siRNA portfolio Ensure the delivery of high-quality siRNA products for both in vitro screening and in vivo evaluation within drug candidate pipelines. Collaborate with discovery xRNA existing oligonucleotide synthesis teams in Basel as well as in Cambridge Provide technical leadership to the scale-up team in the synthesis of oligonucleotides, optimize methodologies and processes to improve efficiencies Collaborate with synthetic chemists and project teams to scale up new siRNA chemistries that address critical scientific challenges and facilitate their seamless transition into development. Document and effectively communicate results and scientific insights to internal and external stakeholders through patent applications and scientific publications. Mentor and support team members by sharing technical expertise and hands-on experience within the work environment. Excellent problem solving skills and solution orientated mindset Qualifications and Requirements A PhD in synthetic chemistry focused on oligonucleotides. 2-3 years experience in the industry setting Proven practical experience in oligonucleotide solid phase synthesis and downstream processing with an expertise in a mid/large scale oligo synthesis and in process development. Demonstrated leadership abilities and experience developing scientific teams. Capacity to promote and implement innovative ideas within a global team context. Strong independent problem-solving skills. Proven collaborative attitude Proficiency in managing multiple priorities effectively while maintaining focus where necessary. Excellent verbal and written communication abilities. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Strategic Assistant will report directly to International Medical Affairs (IMA) head and act as their primary advisor and point person. This strategic and operational position is responsible for developing and ensuring the execution of strategic plans, projects, and commitments which drive operational efficiencies and connectivity across stakeholder groups. Additionally, this role is responsible for keeping the IMA Head apprised of key initiatives, providing project oversight and management of cross-functional and key initiatives, and ensuring appropriate coordination and management of budgets and integrated project plans for the IMA. The Strategic Assistant is a key partner on a variety of strategic, operational, and organizational matters. This role provides dedicated support to the IMA head in achieving team objectives, shaping the agenda, and ensuring execution through operational management and moderation of governance bodies, leadership team, and projects. It supports proactively identifying and resolving upcoming issues and improving processes. About the Role Key Responsibilities: Serves as a strategic thought partner with the IMA Head, providing high-level executive support associated with complex problems, current and future initiatives, strategies, and budgets. Assists the IMA Head in day-to-day responsibilities, ensuring coordination of cross-organizational activities. Develops a clear understanding of IMA ambition and key priorities to provide operational leadership as a member of the International leadership team. Demonstrates collaborative leadership and influence necessary to ensure alignment among key stakeholders and seamless execution of deliverables. Works cross-functionally to ensure the strategic and operational plans are delivered Works with Finance partners and IMA leaders to ensure budget alignment and validation with the head of IMA Serves as an ambassador for the IMA Head and leadership team, facilitating communication with other members of the organization as needed. Leads IMA LT meetings including agenda, action planning, tracking deliverables, and KPIs. Responsible for IMA team’s governance: Drives agenda, moderates meetings, and minutes. Actively shapes team priorities and the alignment of goal setting across cross-functional teams. Ensures effective operational management of critical decision-making bodies. Looks for opportunities to simplify and drive synergies between teams in the organization. Coordinates and anticipates timely preparation of IMA content for critical internal and external meetings. Supports change management, culture, and OD initiatives together with other IMA LT members. Builds and supports the execution of an internal communications plan aligned to IMA priorities and cultural agenda. Essential requirements: Minimum BS/BA degree, preferably MA, MBA Strategic Consulting background. Strategic capability and commercial acumen. Over 5 years in the Pharma industry, ideally including in a regional/global environment or in a major consultancy. 5+ years of experience in project management, operations, and/or people leadership. Ability to influence without authority. Ability to work independently and collaboratively, strong leadership and organizational skills, and able to drive multiple projects to successful, timely completion. Ability to communicate ideas and data both verbally and written in a persuasive and appropriate manner. Analytical skills to identify the root cause of problems/opportunities and determine possible solutions. Highly autonomous, self-directed, and collaborative. Energetic and hands-on self-starter with a desire to learn new things quickly. Proven ability to refine and improve the organization’s capabilities. Demonstrated track record of effectively handling key organizational matters. Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize on sharing our enterprise strategies while remaining focused on addressing the unique country’s needs as a value-added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio. An opportunity has arisen for an experienced Senior HTA Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA). This role offers the chance to lead the evidence synthesis of patient data from clinical, observational, and real-world data studies supporting HTA submissions, in a flexible and collaborative environment. The role is responsible for leading the design and execution of evidence-synthesis for HTA submissions incl. EU HTA JCA Dossier and for health economic models. Position applies methodological and analytical expertise to predict the value of Novartis assets and develop strategies on how best to demonstrate this to external decision makers. Role will strategically and effectively communicate, and tailor generated evidence to multiple stakeholder audiences. About the Role Key responsibilities: As part of the HEOR & PCO Team: Develop core global Indirect Treatment Comparison (ITC) plan for HTA, payer and other Access stakeholder assessments, submissions, and negotiations. Lead publications associated with these to meet business objectives. Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the Indirect Treatment Comparison (ITC) for local HTA submissions and support the local assessment of HTA strategy. Coordinate data requirements across evidence generations functions (Clinical Development; Medical Affairs/Biostat and HEOR & PCO) to support Pricing & Reimbursement. Set-up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables e.g., statistical analysis plans. Track key HTA statistics priorities and sequence them aligning with resource availability and risks. Identify need for preliminary ITCs to inform value proposition, development, pricing and commercial strategic forecast and decisions. Lead and facilitate the sharing of best practices and key learnings across regions, countries and cross-functional partners. Stay on top of innovative techniques, using robust analytical techniques leveraging available clinical data and published information to inform pricing and market access strategy. Collaborate with the MA Biostats team for trial analyses, HTA challenges, and statistical analyses. Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access (Therapeutic Area Access, Pricing) to ensure alignment to brand and commercial, access and evidence strategy. Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers and publications. Provide mentoring and coaching support to junior members of evidence modelling teams and across function. Essential requirements: The ideal candidate will possess a strong background in statistics, with relevant experience in HTA and clinical research. MSc/PhD in Statistics, Biostatistics, or a related field. Experience from pharmaceutical industry or life-science consultancy 6-8 years relevant experience in consultancy or pharmaceutical industry in Evidence Synthesis, Health Economics, Health Technology Assessment, or related area Strong understanding of clinical drug development and HTA-related regulations and processes Local HTA experience including experience with country HTA submissions Strong understanding of statistical methodologies for indirect treatment comparisons (ITCs) and population-adjusted indirect comparison (PAIC) Proficiency in statistical software such as R and/or SAS Strong interpersonal and scientific communication skills. Excellent problem-solving abilities and attention to detail Ability to lead in a matrix environment and work collaboratively in interdisciplinary cross-functional teams Location: This role can be based in the UK, London but also based in Basel, Switzerland and Dublin, Ireland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Join a dynamic team where you will be managing high-impact patent litigation cases. You'll work closely with both in-house and external counsel, driving strategic litigation efforts and overseeing key operational processes. This role offers the opportunity to lead projects that enhance litigation workflows, contribute to budget planning, and deliver insightful IP reporting—making a real difference in how we protect and leverage our intellectual property. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities : Provides and utilizes IP expertise to support several IP Counsels and the IP function as a whole - championing quality, collaboration and operational excellence in the Department. Contributes to the implementation and application of IP policies and guidelines - providing non-legal advice to business colleagues, collaborating with the business under the supervision of project leads to ensure business goals are met in an efficient and timely manner. Contributes to the #OneNovartisIP culture - Proactively and autonomously supports in-house patent litigation counsel and attorneys in preparation for patent enforcement and defense, by interacting with local counsel and local Business Franchises. Maintain and share advanced knowledge of latest litigation rules and adapting practices to comply. Monitor and updating Anaqua on a daily basis. Communicate effectively with colleagues, agents and other associates - Actively participate in litigation group and cross-divisional meetings as needed – being flexible to provide support in other areas within the Patent Support team (i.e. invoicing and data input). Leads teams in development of procedures and processes - ability to conduct meetings as needed; Recommends areas/systems of possible improvement in efficiencies in procedures. Leads projects relating to litigation processes/operations, driving the successful implementation of new and revised processes and guidelines. Autonomously supports in-house patent litigation counsel and attorneys on matters such as patent ownership and licensing structure. Manages the flow of information by acting as a contact point for local lawyers/local team for patent litigation matters – using Litigation database document and information management; familiarity with patent databases e.g. PatBase, Espacenet, etc. Attend and draft memorandum of litigation meetings with local counsel and local business, provide action points and follow up on agreed objectives. Manages the IP Litigation budget process; drive the preparation of and deliver the various litigation budget forecasts by liaising with internal and external attorneys & counsel, as well as BPA, assisting in the review, as appropriate. Responsible for full project life cycle including Liaises with department eBilling coordinator, utilizes Anaqua to record and report litigation matters, litigation reporting and leads the interactions on behalf of IP Litigation Project Team with any third-party co-owners, licensors, patentees. Supervision of junior litigation paralegals, local litigation team coordinators and new team members providing guidance on internal and external processes, litigation database management, etc. Essential Requirements: Relevant degree, or equivalent experience. Paralegal qualification/ certifications or equivalent Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as an IP paralegal or equivalent in an IP litigation law firm or corporation. Extensive experience in autonomously providing complex patent litigation support in a large multinational company preferably in-house, or in a law firm. Able to work autonomously in preparation of draft schedules and supporting documents for subsequent attorney review - able to communicate with business clients in multiple countries. Excellent team-player with exemplary interpersonal skills - Reliable, service-oriented with impeccable integrity and willingness to learn. Proven ability to balance and identify priorities in daily work, manage varying workload levels, ensuring a consistent work product, and support the IP team efficiently and in a solution-oriented, contextualized manner. Proactive approach to project/workstream involvement. Able to consider the needs of the team and where they can contribute, implementing or suggesting solutions prior to being instructed. Active participation in relevant projects - willingness to learn and develop in role. Extensive experience in autonomously managing complex patent litigation support in a large multinational company, preferably in-house, or in a law firm. IP Identified leadership potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Join us as the Site Quality Head and lead the charge in ensuring world-class quality and compliance at one of Novartis’ strategic manufacturing sites. In this pivotal role, you’ll shape quality standards, safeguard patient trust, and drive operational excellence across all GxP functions. Your leadership will not only uphold regulatory compliance but also inspire a culture of continuous improvement and collaboration. If you’re passionate about making a tangible impact on global healthcare, this is your opportunity to lead with purpose. About the Role Key Responsibilities: Lead the Site Quality organization and foster a culture of compliance and continuous improvement. Ensure full adherence to cGMP, regulatory requirements, and Novartis Quality Manual standards. Act as Qualified Person (Technical Responsible Person) for site operations. Oversee quality governance across all GxP functions and ensure robust risk management. Final responsible to approve or reject raw materials, facilities, utilities, and finished products. Drive execution of training programs and maintain compliance with DI and eCompliance standards. Manage internal and external audits, inspections, and regulatory submissions. Ensure effective complaint investigations and exception management processes. Essential Requirements: 10–15 years of experience in the pharmaceutical or chemical industry. University degree in Chemistry or Pharmacy or related discipline (per Swiss law also Biology would be acceptalbe) Strong knowledge of regulatory requirements and cGMP standards. Experience with FDA/Swissmedic regulations and compliance. Dynamic, resilient, and versatile approach to problem-solving. Demonstrated people leadership and team management skills. Excellent communication skills and ability to collaborate across functions. Fluency in German and English. Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10067576 Dec 03, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: The Technical Project Leader (TPL) formulates and drives a scientifically sound and business driven technical project strategy for Technical Research & Development (TRD), including financial planning, risk assessments and contingency planning as appropriate and in line with the overall Research & Development Project Team strategy and TRD objectives. The TPL will lead the TRD-development of Mixed Modality, Small Molecule and/or Biologics projects as well as leading, representing, managing, and supporting the CMC team, ensuring alignment with other departments and functions inside and outside of TRD as well as third parties as appropriate About the Role Strategy Establishes technical development plans in line with priority classification of project, gated by clinical readouts as appropriate and with an enterprise view in consideration of overall portfolio priorities. Establishes high level summaries for presentation to management and stakeholders. Has advanced skill to identify, assess, manage, and communicate CMC risks / program risks. Due to seniority and experience, can handle more difficult risks, issues in more complex projects and handle multiple risks of DS/DP/Device even with junior CMC team members. Provides drug development expertise in addition to technical expertise. Follows standard process but at the same time thinks outside the box based on existing knowledge. Challenges the status quo, is curious and fosters creativity of team members and own creativity. Leverages existing knowledge and implements in the overall Global Project Team project strategy. Continues to follow and stands behind Global Project Team decisions. For complex late phase programs, supports Senior TPL for defined work packages. Interfaces Participates in boards and joins and/or can lead discussions in leadership teams. Is highly skilled in collaborative settings (i.e., external vs internal, CROs, DDs, in-/out-licensing settings). Approaches/analyses issues and collaborates with other line functions for optimal solutions. Takes into account multiple stakeholder perspectives and approaches to find optimal solutions and build commitment and consensus. Provides knowledge of industry, main competitors, customers and external environment - this includes healthcare industry and global industry, digital and technological advancements. Shares knowledge with CMC community, e.g., by lessons learned sessions. Uses knowledge and experience to challenge and influence CMC line functions and/or Global Project Team in background of the overall drug development strategy / industry insight. Actively contributes to Global Project Team beyond CMC line functions. Is able to navigate and manage the complexity of the disease area GPTs. Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. People Learns to manage teams/stakeholders appropriately (utilizing their support). Brings forward sound proposals and shares lessons learned, without passing the blame. Anticipates setbacks and stays in control - takes criticism as intended for situations (not personally or toward particular individuals). Recovers quickly from problems and setbacks. Exhibits servant leadership and provides mentoring/coaching to junior TPLs, line functions and CMC team members to support their professional and personal growth. Leads by example and drives decisions. Generic Activities Leads CMC teams (in a matrix set up). Leads CMC team and other meetings (agendas, minutes, action tracker, moderation). Acts as link and conveys CMC topics between Global Project Team, CMC line functions and CMC boards to support decision making. Sets the CMC team and sub-teams objectives in line with the GPT / PoC Team objectives. Communicates transparently. Is able to communicate and adjust the message based on the audience (i.e., level of technical detail, etc.). Has financial and resource oversight, budget accountability/oversight. Takes responsibility for successes and failures of own and team's work, holds self and team accountable for outcomes (shifts priorities to ensure success). Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. Ideal Background Education (minimum/desirable): Advanced degree in life science, engineering or equivalent. Languages: Fluent in English Experience/Professional requirement: Successfully demonstrated several years (minimum of 2-3 years) of directly related experience as functional project leader and relevant experience as Associate TPL or equivalent. Has strong scientific/technical knowledge & understands technical development tasks for Small Molecules or Biologics (minimum) and Mixed Modalities (ideal). Is able to establish/maintain DS/DP/Device supply plan (in alignment with the clinical supply project lead). Has fundamental knowledge of GMP and regulatory requirements. Has a solid cross-functional knowledge (PK/PD, tox, clinical, commercial) regarding drug development. Manages end to end technical drug development and knowledge. Completed basic project management training. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Development Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Mengeš, Slovenia Alternative Location 2 Schaftenau, Austria Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10066548 Nov 18, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: We are seeking a highly motivated and experienced PhD-level scientist to lead our mid/large xRNA synthesis team in Basel. This position requires extensive collaboration within a multidisciplinary environment, bridging research and development to discover and advance innovative siRNA therapies addressing significant unmet medical needs. About the Role Key Responsibilities Oversee a state-of-the-art oligonucleotide synthesis facility, managing both capital and consumables budgets efficiently. Lead and guide a team of scientists specializing in oligonucleotide synthesis and purification of oligonucleotides at millimole scale to deliver on our growing siRNA portfolio Ensure the delivery of high-quality siRNA products for both in vitro screening and in vivo evaluation within drug candidate pipelines. Collaborate with discovery xRNA existing oligonucleotide synthesis teams in Basel as well as in Cambridge Provide technical leadership to the scale-up team in the synthesis of oligonucleotides, optimize methodologies and processes to improve efficiencies Collaborate with synthetic chemists and project teams to scale up new siRNA chemistries that address critical scientific challenges and facilitate their seamless transition into development. Document and effectively communicate results and scientific insights to internal and external stakeholders through patent applications and scientific publications. Mentor and support team members by sharing technical expertise and hands-on experience within the work environment. Excellent problem solving skills and solution orientated mindset Qualifications and Requirements A PhD in synthetic chemistry focused on oligonucleotides. 2-3 years experience in the industry setting Proven practical experience in oligonucleotide solid phase synthesis and downstream processing with an expertise in a mid/large scale oligo synthesis and in process development. Demonstrated leadership abilities and experience developing scientific teams. Capacity to promote and implement innovative ideas within a global team context. Strong independent problem-solving skills. Proven collaborative attitude Proficiency in managing multiple priorities effectively while maintaining focus where necessary. Excellent verbal and written communication abilities. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10067434 Dec 03, 2025 Switzerland Summary Linienführer:in Primärverpackung - Feste Darreichungsformen Für unser Team in der Primärverpackung fester Darreichungsformen suchen wir per sofort eine:n motivierte:n und erfahrene:n Linienführer:in mit fundierten GMP-Kenntnissen, ausgeprägtem technischem Verständnis und Teamgeist. In dieser Funktion sind Sie verantwortlich für die termingerechte Ausführung der Ihnen zugewiesenen Herstellungs- und Verpackungsaufgaben gemäß Produktionsplan unter Einhaltung aller GMP-, Sicherheits- und Umweltrichtlinien. About the Role Hauptaufgaben Maschinelles Verpacken von Arzneimitteln (Flaschen und Blister) an modernen, komplexen Verpackungsanlage Führen, Einteilen und Unterstützen des Anlagenteams der zugewiesenen Produktionslinie Umrüsten/ Einrichten und Anfahre/Betreiben der Produktionsanlagen Verantwortung für die Anlagenreinigung und Desinfektion Durchführung von In-Process-Control (IPC)-Kontrollen Auftragsvorbereitung in Zusammenarbeit mit Planung, Lager und Prozessexpert:innen Beheben kleiner technischer Störungen; Unterstützung bei Qualifizierungs- und Instandhaltungsarbeiten nach Bedarf Einarbeitung neuer Mitarbeitender im Bereich Korrekte, vollständige und nachvollziehbare Dokumentation der Tätigkeiten auf Papier und in der elektronischen Chargendokumentation (z. B. SAP) gemäß GMP Fachansprechpartner:in für die zugewiesenen Anlagen und Prozesse bei Audits und Inspektionen Sicherstellung und Durchsetzung von GMP- und HSE-Vorgaben Mitwirkung am Housekeeping (Ordnung, Sauberkeit, 5S) im Produktionsbereich Kontinuierliche Verbesserung: Identifikation von Schwachstellen und Vorschlag von Maßnahmen (Organisation, Prozess, Sicherheit, Hygiene) Teilnahme an allen funktionsrelevanten Schulungen und Sicherstellung des geforderten Trainingsstandes Bereitschaft zu Mehrarbeit bzw. Schichtarbeit (Früh- und Spätschicht), sofern erforderlich Zusammenarbeit mit anderen Einheiten und Einsatz in angrenzenden Bereichen bei Bedarf (z. B. weitere Primärverpackungslinien, Lager, Sekundärverpackung, Manuelle Handverpackung) Erforderliche Fähigkeiten Abgeschlossene Ausbildung im Bereich Chemie / Pharma oder Technik Berufserfahrung als Linienführer:in/Linienleiter:in im GMP-regulierten Umfeld, idealerweise in der Verpackung pharmazeutischer Produkte (Flaschen und Blister)Ausgeprägte technische Kompetenz mit Erfahrung im Einrichten, Bedienen und Störungsbeheben an automatisierten Produktionsanlagen Hohes Pflicht- und Qualitätsbewusstsein; sorgfältige Dokumentations- und Arbeitsweise sowie Ordnung und Sauberkeit am Arbeitsplatz Konstruktiv, lösungsorientiert, verantwortungsbewusst; tiefes Verständnis für Qualität und Compliance Hohe Selbstmotivation und schnelle Auffassungsgabe zur Einarbeitung in neue Tätigkeiten Erfahrung in der Führung kleiner Teams und in der Mitarbeitendenausbildung von Vorteil Gute IT- sowie MS-Office-Kenntnisse (z. B. Erstellung einfacher Arbeits- oder Bedienungsanweisungen) Fundierte Kenntnisse im GMP-Umfeld und in hygienekritischen Bereichen Organisationstalent und Durchsetzungsvermögen Sehr gute Deutschkenntnisse in Wort und Schrift; Englischkenntnisse von Vorteil Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Development Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.