Novartis AG

Summary With over 60 years history in neuroscience, Novartis brought landmark therapies to patients with Multiple Sclerosis, Alzheimer’s disease, Parkinson’s Disease, Epilepsy, Depression and Migraine. We have a world-class pipeline in neuro-inflammation, neurodegeneration, psychiatric and neuromuscular diseases. Our holistic R&D approach includes cutting edge molecules, comprehensive approaches to technology, biomarker and digital therapeutics to propose better solutions for patients worldwide. About the Role As Global Program Clinical Head (GPCH), you are the clinical lead of Neuroscience, full development product. As a key member of the Global Program Team, you will contribute to the overall strategy in collaboration with relevant other functions such as Regulatory Affairs, Market Access and others. You will develop and ensuring the implementation of the Clinical Development plan and leading a cross functional team of specialists such as Medical Directors, Trial Directors, Safety Leaders, Biostatisticians and Regulatory Directors. The GPCH works to ensure early development plans and proof of concept studies are aligned with Development strategy and leads licensing evaluations for Clinical Development for the therapeutic area. In addition, you will lead the development and execution of the disease area strategy. What you’ll be doing: Responsible for clinical input to support Business Development & Licensing (BD&L) activities Serve as the Clinical Development Representative to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) Contribute to Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or more treatment indications and/or multiple programs. Drive creation and implementation of Clinical Development to support decision analysis and optimal resource allocation in program(s). Lead a cross functional team through the creation of clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency. As the medical expert, lead interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs, Marketing, Health Economics & Outcomes Research), and internal decision boards Together with Patient Safety, ensure continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Support registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Plan and implement publication and clinical communication strategy in coordination with Global Medical Affairs and Medical Writing, and provide input into key external presentations What you’ll bring to the role: MD, or PH. D degree with 10+ years’ experience in clinical research or drug development in an industry environment spanning clinical activities in Phases I-III/IV, including submission dossiers. A passion for Neuroscience Advanced expertise in Neuroscience with ability to innovate in clinical development study designs, provide relevant evidence to decision-makers and to interpret, discuss and present clinical trial or section program level data Detailed knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Desirable: MD or equivalent, MD or MD/PhD in Neurology, Experience in Cell&Gene, Rare or Neuromuscular diseases, Neuroinflammation of interest (preferred). This is a hybrid role and it can be based in Basel, London or Barcelona. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, colour, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10029778 May 19, 2025 Switzerland Summary As our Clinical Development Medical Director in our Immunology Development Unit you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. About the Role The Clinical Development Medical Director (CDMD) for Rheumatology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years- experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons. This hybrid role can be based in Basel, London, Barcelona, Madrid or Dublin. *R ead our handbook to learn about all the ways we-ll help you thrive personally and professionally: *Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Barcelona Gran Vía, Spain Alternative Location 2 Dublin (NOCC), Ireland Alternative Location 3 London (The Westworks), United Kingdom Alternative Location 4 Madrid Delegación, Spain Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10053425 Jun 10, 2025 Switzerland Summary As Executive Assistant you will act as an administrative support of the leader and the team within the International Strategy team. You will responsible for managing, planning, coordinating, and communicating - administrative and organizational activities for the Head of International Strategy and the strategy team. About the Role Key Responsibilities: Your responsibilities include, but are not limited to Administrative support & on- and off boarding for leader/team Being responsible for independently providing secretarial and administrative support for the leader and the team Arrange and follow up on national and international travel arrangements such as visas and other requirements/ reservations, involving multiple locations and individuals and process all related travel expenses. Day-to-day calendar management with internal and external stakeholders Support of communication activities such as announcement process, Teams maintenance, updating of distribution lists etc. Budget activities specific to the necessities of leader / team. Preparation of technical/ presentations, graphs and spreadsheets and management reports, as well as taking minutes, creating contact lists, correspondences, and emails Manage all requirement for onboarding and offboarding of team members/management and coordination of access rights (Workday, badge, Teams access, IT equipment, etc.) Pre-define the admin that will cover the role in extended leaves Drive digitalization of processes and meetings/workshops Close collaboration with other ILT Executive Assistants Support broader business team on special scheduling / planning activities, if and when needed Meeting coordination and Event & project management Organizing and coordinating key meetings and department meetings - including venues for large meetings. Preparation of materials for the meeting and take minutes accordingly. Leadership meeting preparation in alignment with leader & team: Agenda, pre read distribution, taking minutes, coordination of key speakers Support and lead smaller projects related to the function/team priorities Essential Requirements: Commercial training (for Switzerland e.g. Swiss Association of Commercial Employees, business school) or equivalent (e.g. other vocational qualification, must have very good administrative skills/experience) Good written and spoken English (and for Switzerland German, knowledge of other languages (e.g. French) advantageous) 5+ years of experiences in an administrative supporting function with senior leadership team Proven ability to collaborate effectively within an international matrix organization Outstanding communications skills, both verbal and written Outstanding flexibility, adaptability, and sense of client service, strong in collaborating with other assistants in ILT Strong in prioritizing tasks across multiple stakeholders Flexibility and agility in handling last minute job requirements. Able to handle stressful situations with measured calmness and decisiveness. Strongly preferred significant previous experience with ILT leaders and International experience Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Finance Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Facilities & Administration Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10053278 Jun 10, 2025 Switzerland Summary We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. This applied research program is designed to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a fellow, you will learn to apply your quantitative and computational skills to make a difference for patients and reimagine medicine at Novartis. As part of the Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Drug hunting is a team sport, and you will gain experience in Data Science & AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Seize this chance to be at the forefront of Data Science and AI, and shape the future of drug discovery! This project aims to perform human genetics-driven target discovery for immunological diseases. The successful candidate will establish a pipeline of statistical and machine learning models to identify causal variants, map them to likely target genes, and describe potential underlying mechanisms. We will apply this pipeline to immune system-driven diseases to formulate clear hypotheses on novel drug targets and test them experimentally. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Data Science Innovation Postdoctoral Fellow, you will: Work independently as well as within interdisciplinary teams to drive your project Analysis, integration, and visualization of human genetics with complementary omics data Apply statistical and machine/deep learning methods to identify disease associated variants, their target genes and regulatory mechanism Analyze omics datasets to formulate and/or support hypotheses generated by ML models Effectively collaborate with wet lab scientists to validate in silico findings Role requirements : PhD in Genetics, Computational Biology or a related field (Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD, i.e. PhD degrees must have been awarded May 2023 or later). Excellent skills in computational and statistical analysis of genetics and omics data (GWAS, QTLS, transcriptomics and chromatin omics) Excellent skills in programming, data visualization and reproducible research in R/Bioconductor and/or Python Experience with machine/deep learning methods is considered a plus Experience in Immunology is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity #DSIF How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary #onsite Location: Basel, Switzerland Level: Principal Scientist II or Senior Principal Scientist Full time, onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis’ purpose. We are looking for a highly motivated and independent scientist with strong expertise in parallel purification and automation. You will be complementing our existing team of separation and analytical experts with your passion and experience in designing and implementing integrated and automated workflows for the purification of new and emerging modalities. The successful candidate will understand projects in the context of the overall process and will be integral to their success by taking a leadership role in providing customized solutions, thereby directly contributing to the discovery of new medicines! About the Role Your responsibilities will include, but are not limited to: Develop, implement, and oversee innovative solutions and workflows to advance parallel purification and analytics platforms that support diverse chemical modalities, including peptides, oligonucleotides, and low molecular weight (LMW) compounds Implement and maintain robust, scalable, high-throughput purification platforms for peptides and additional modalities at different scales and with associated analytical processes Refine and optimize ongoing library purification workflows. Collaborate with cross-disciplinary teams and external partners to adapt equipment and processes in response to changing needs. Work closely with cross-site and cross-functional partner groups to support harmonized digital workflows, hardware setups, and data integration. Drive data standardization and advance capabilities for active learning Lead and mentor a team of experienced scientists. Cultivate an environment of professional growth and scientific excellence, empowering team members to develop and deliver impactful results Anticipate emerging trends and future needs in automation solutions for purification and analytics. Drive forward-thinking strategies by working closely with chemists and project teams to enable cutting-edge solutions aligned with GDC’s evolving priorities Serve as a subject matter expert within the organization by sharing domain-specific expertise, introducing novel techniques, and fostering creativity and resourcefulness. Contribute to shaping the group’s strategic vision and future Actively participate in global internal and external scientific communities through presentations, publications, and professional networking What you will bring to the role: Science or engineering degree (PhD or Master’s) and at least 5 years of post-degree experience in automation and purification, ideally in a drug discovery setting State-of-the-art knowhow and recent hands-on experience in implementing automation solutions, including digital workflows (software/hardware), troubleshooting hardware systems, and proficiency with current data workflow and analysis software packages Demonstrated expertise in peptide purification; experience in oligonucleotide and low molecular weight compound processing is highly desirable Hands-on experience with Laboratory Information Management Systems (LIMS) to manage workflows, data tracking and analytical reporting in a high-throughput environment A track record of coaching, mentoring, and leading a team of scientists as well as in establishing and driving cross-site and interdisciplinary collaborations History of initiating and driving projects independently to completion, with strong organizational skills and attention to detail Exceptional collaboration and communication skills, ability to work effectively within a matrixed organization and build consensus across diverse teams and stakeholders Strong connections within external networks in the parallel purification and automation community are highly desirable Proficiency in English (written and spoken) is required Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053205 May 27, 2025 Switzerland Summary #onsite Location: Basel, Switzerland Level: Principal Scientist II or Senior Principal Scientist Full time, onsite At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis- purpose. We are looking for a highly motivated and independent scientist with strong expertise in parallel purification and automation. You will be complementing our existing team of separation and analytical experts with your passion and experience in designing and implementing integrated and automated workflows for the purification of new and emerging modalities. The successful candidate will understand projects in the context of the overall process and will be integral to their success by taking a leadership role in providing customized solutions, thereby directly contributing to the discovery of new medicines! About the Role Your responsibilities will include, but are not limited to: Develop, implement, and oversee innovative solutions and workflows to advance parallel purification and analytics platforms that support diverse chemical modalities, including peptides, oligonucleotides, and low molecular weight (LMW) compounds Implement and maintain robust, scalable, high-throughput purification platforms for peptides and additional modalities at different scales and with associated analytical processes Refine and optimize ongoing library purification workflows. Collaborate with cross-disciplinary teams and external partners to adapt equipment and processes in response to changing needs. Work closely with cross-site and cross-functional partner groups to support harmonized digital workflows, hardware setups, and data integration. Drive data standardization and advance capabilities for active learning Lead and mentor a team of experienced scientists. Cultivate an environment of professional growth and scientific excellence, empowering team members to develop and deliver impactful results Anticipate emerging trends and future needs in automation solutions for purification and analytics. Drive forward-thinking strategies by working closely with chemists and project teams to enable cutting-edge solutions aligned with GDC-s evolving priorities Serve as a subject matter expert within the organization by sharing domain-specific expertise, introducing novel techniques, and fostering creativity and resourcefulness. Contribute to shaping the group-s strategic vision and future Actively participate in global internal and external scientific communities through presentations, publications, and professional networking What you will bring to the role: Science or engineering degree (PhD or Master-s) and at least 5 years of post-degree experience in automation and purification, ideally in a drug discovery setting State-of-the-art knowhow and recent hands-on experience in implementing automation solutions, including digital workflows (software/hardware), troubleshooting hardware systems, and proficiency with current data workflow and analysis software packages Demonstrated expertise in peptide purification; experience in oligonucleotide and low molecular weight compound processing is highly desirable Hands-on experience with Laboratory Information Management Systems (LIMS) to manage workflows, data tracking and analytical reporting in a high-throughput environment A track record of coaching, mentoring, and leading a team of scientists as well as in establishing and driving cross-site and interdisciplinary collaborations History of initiating and driving projects independently to completion, with strong organizational skills and attention to detail Exceptional collaboration and communication skills, ability to work effectively within a matrixed organization and build consensus across diverse teams and stakeholders Strong connections within external networks in the parallel purification and automation community are highly desirable Proficiency in English (written and spoken) is required Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10051724 May 12, 2025 Switzerland Summary We are seeking a motivated QC-Analyst for Biopharmaceutical Production within the framework of raw materials, drug substance, and in-process controls. The candidate will perform analytical testing and ensure compliance with SOPs, analytical methods, and compendial standards. About the Role Major accountabilities: · Conduct and coordinate quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements · Independent planning, implementation, and evaluation of routine and special analyses in a GMP-regulated environment · Interpret test data, prepare detailed reports, and maintain accurate record of test results. · Troubleshoot testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis · Conducting microbiological tests such as total germ count determinations (MET) and bacterial endotoxins (BET) · Participate in the validation of analytical procedures · Collaborate closely with the internal teams to optimize quality control processes · Instrument responsibilities, including qualification, maintenance, and calibration documentation · Support in ensuring that the laboratory is maintained in a ready state of inspection. Key performance indicators: · Timely test record completion and accurate processing without delays · Prompt reporting of missed deadlines and aim for shortest possible lead times · Continuous readiness for inspection · Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities · Proactively identify and implement cost-reducing optimizations · Complete all assigned training as per the provided plan Minimum Requirements: · Completed scientific education (e.g., Laboratory Technician, Bachelor or Master) · Practical experience in a GMP-regulated lab and document creation · Knowledge in common analysis techniques, especially HPLC and photometry; microbiological knowledge is an advantage · Working experience in laboratory environment in the pharmaceutical industry · Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage · Ability to work precisely, independently, and proactively · Reliability, flexibility, resilience, and strong teamwork skills · Shift work with normal working times (one shift) including weekends Skills: · Continuous learning · Dealing with ambiguity · Decision making · GMP · Industry standards · Laboratory equipment · Laboratory excellence · Quality Control (QC) testing · Quality Control sampling · Self awareness · Technological expertise Languages : · Fluent in German (spoken and written) and proficient in English Skills Desired Continued Learning, Dealing With Ambiguity, Decision Making Skills, Gxp, Industry Standards, Laboratory Equipment, Laboratory Excellence, Quality Control (Qc) Testing, Quality Control Sampling, Self-Awareness, Technological Expertise Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: The Analytical Expert designs and plans scientific experiments as well as report and interpret results/outcome in line with the overall Analytical R&D project strategy for Drug Substance(s) and Drug Product(s) in development. He ensures project knowledge generation and preparation/timely delivery of supplies with high quality and state of the art standards. He leads and manages assigned project / network activities / support/coach team members. Finally, he contributes to the analytical project strategy definition; drive scientific and operational excellence and thereby contribute to overall Novartis Technical R&D strategy and goals for New Chemical Entities (NCE). About the Role Analytical Research and Development (ARD) sits within Development / Technical R&D and plays an essential role in the characterization, analysis and control strategy definition of small molecules and synthetic large molecules Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to commercial production. We are looking for highly motivated Analytical Experts in the field of small molecules for oral administration focusing on early development including pre-clinical activities and/or late phase development, registration and launch preparation activities. Your responsibilities will include, but are not limited to: Designing, planning, supporting the execution as well as interpreting and reporting results of scientific experiments for the development and timely supply of drug substances (DS) and drug products (DP) intended for pre-clinical and clinical development as well as potential commercialization. Interpreting analytical data as well as authoring & reviewing supportive analytical documents (e.g analytical procedures, specifications, product characterization reports, validation protocols/reports, stability protocols/reports as well as batch records compilation and line function material disposition for stability and release testing) and aligning the corresponding activities within a global project team. Managing interactions with internal and external stakeholders, including outsourced activities to CROs by providing scientific and technical guidance whenever necessary. Proactively identifying scientific, technological and GMP challenges, propose creative solutions and communicate key issues to the appropriate management level and respective technical project team. Collaborate with the Analytical Project Leaders, analytical project team members, wider analytical community as well as partnering technical functions applying state of the art analytical science, technologies and processes. Working according to appropriate SOPs, GMP, Quality Directives, Health and Safety & internal Novartis guidelines. In order to successfully fulfill this role the analytical expert should bring the following qualifications: Minimum: Bachelor in analytical chemistry or equivalent with significant experience in analytical development of drugs. Desirable: Advanced degree in a relevant life science scientific area (e.g. Master, Ph.D. or equivalent in chemistry / pharmaceutical or analytical science). Preferably 5 years’ experience in the pharmaceutical industry with a track record in GMP activities for development or marketed products. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a global and highly dynamic environment. Advanced knowledge of analytical techniques and associated processes (e.g. HPLC and corresponding Chromatographic Data System, Dissolution rate, GxP Quality Management Systems, statistical evaluation tools ...). Additionally, considering that the activities will primarily focus on the development of oral dosage forms, knowledge in dissolution rate testing as well as drug substance solid state properties such as particle size distribution, solubility and polymorphism is essential. Good presentation skills and scientific/technical writing skills and associated IT Tools. Fluent in English (oral and writing), German is advantageous. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053278 Jun 06, 2025 Switzerland Summary We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. This applied research program is designed to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a fellow, you will learn to apply your quantitative and computational skills to make a difference for patients and reimagine medicine at Novartis. As part of the Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 2 years in length, with the option of applying for an extension of up to 1 year. Drug hunting is a team sport, and you will gain experience in Data Science & AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Seize this chance to be at the forefront of Data Science and AI, and shape the future of drug discovery! This project aims to perform human genetics-driven target discovery for immunological diseases. The successful candidate will establish a pipeline of statistical and machine learning models to identify causal variants, map them to likely target genes, and describe potential underlying mechanisms. We will apply this pipeline to immune system-driven diseases to formulate clear hypotheses on novel drug targets and test them experimentally. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Data Science Innovation Postdoctoral Fellow, you will: Work independently as well as within interdisciplinary teams to drive your project Analysis, integration, and visualization of human genetics with complementary omics data Apply statistical and machine/deep learning methods to identify disease associated variants, their target genes and regulatory mechanism Analyze omics datasets to formulate and/or support hypotheses generated by ML models Effectively collaborate with wet lab scientists to validate in silico findings Role requirements : PhD in Genetics, Computational Biology or a related field (Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD, i.e. PhD degrees must have been awarded May 2023 or later). Excellent skills in computational and statistical analysis of genetics and omics data (GWAS, QTLS, transcriptomics and chromatin omics) Excellent skills in programming, data visualization and reproducible research in R/Bioconductor and/or Python Experience with machine/deep learning methods is considered a plus Experience in Immunology is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity #DSIF How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Job ID REQ-10049881 Jun 06, 2025 Switzerland Summary Are you someone who can display creativity in the field of analytical science & technology - with an interest in analytical lifecycle management? As a Senior QC Specialist in ChemOps you will have a leading role in driving current and future analytical control strategies for new chemical entities (including oligonucleotide projects) ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Major accountabilities: Analytical project lead for launch and lifecycle management of projects in collaboration with multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Inspire analytical and process innovation. Drive and implement the improvement of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Apply your knowledge and expertise by providing training and mentoring to empower colleagues. Education: MSc or PhD in analytical chemistry, organic chemistry or related field + 5 years industry experience Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10051970 May 21, 2025 Switzerland Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process Good knowledge of oncology and experience in early clinical development preferred. Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary As a core member of the Clinical Trial Team (CTT) independently managing all vendor-related aspects of global clinical trial(s) to deliver study outcomes within schedule, budget, quality/compliance and performance standards, you’ll be accountable for vendor service delivery at study level and collaborate closely with the Vendor Start-up Manager (VSM) for selected services (central labs, electronic clinical outcomes assessment/electronic patient reported outcomes (eCOA/ePRO), interactive response technology (IRT), cardiac and respiratory diagnostics, patient recruitment and retention (PR&R), and imaging reading) during study start-up and leverage your technical and study start-up (SSU) expertise to ensure a timely study start-up. About the Role Key responsibilities: Close interaction and collaboration with study team lead and study team members during study lifetime Review of vendor related protocol sections during protocol development Collaborate with Vendor Start Up Manager to the development of Study Specification Worksheet (SSW) to facilitate bid process. If no VSM is assigned to the category, drive the SSW completion. Manages interface with vendors in cooperation with vendor partner functions Quote/proposal review in collaboration with procurement, support contract negotiations and contributes= to the development of vendor contract amendments Accountable for vendor cost control and vendor service excellence Initiates/co-ordinates vendor kick-off meeting for categories not covered by VSMs Attends vendor kick-off meeting for VSM supported categories Essential requirements: Timely, efficient, and quality execution of assigned trials and trial-related activities within budget, and in compliance with quality standards. Vendor service excellence at study level Proactive operational planning with effective contingency and risk mitigation plans Vendor KPI and KQI dashboards Site readiness monitoring Timely completion of UAT for eCOA and IRT Vendor cost control Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: • Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area • Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents • Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders • Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) • Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. • Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: ∙ Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise ∙ Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. ∙ ≥ 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. ∙ Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process ∙ Good knowledge of oncology and experience in early clinical development preferred. ∙ Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Global Program Clinical Head (GPCH) is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy. About the Role The role reports into the Clinical Development Head. Your responsibilities will include: • Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on NIBR clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-Development Decision Point, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. Minimum Requirements: MD or equivalent (required) PhD (preferred) 5 years professional experience as MD and a minimum of 10 years of experience with clinical drug development in an industry environment spanning clinical activities in Phases I through III/IV and experience with leading submission dossiers (required) Ideally a Board certified Nephrologist OR extensive (> 5 years) experience in clinical development withing the Nephrology Therapeutic area Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry This is a hybrid role based in Basel. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Pricing Director (PD) will drive the development of launch and in-market pricing strategies that enable access for our products in partnership with relevant functions (TA, S&G, Access, HEOR, Policy, Finance, etc.). The role requires the right capabilities and the right mindset to drive collaboration, impact, and innovation to realize our short- and long-term goals to fulfill our vision. The PD is expected to be a thought leader and expert in assigned therapeutic/disease area(s) and a strategic partner to internal stakeholders. The PD is expected to support assigned countries on the pricing implementation side ensuring that price decision making is done according to governance. About the Role Key responsibilities: Pricing Director will partner with stakeholders to: Develop, review, and execute pricing strategies for assigned compounds/indications within assigned areas. Responsible for ensuring alignment with program and brand strategies to optimize brand value and market access. Collaborate on pricing research with other IM functions, assigned countries/regions (as needed). Identify competitive trends, synthesize competitor price information (including biosimilars and generics), and trigger actions as required. Design and oversee global launch sequence optimization for assigned assets/indications. Coordinate with assigned countries and other International functions to ensure pricing and access are optimized as impact is felt across markets. Develop and co-create models to optimize pricing and access and recommend adaptations where appropriate. Provides input, as needed, into the price assessment of early-stage products and due diligence projects to validate price, dosing, endpoint, and comparator selection from a price implementation and realization point of view. Develop loss of exclusivity (LoE) strategy to help mitigate erosion in exposed indications. Be an expert on assigned countries and share knowledge regarding major developments in these markets. Interact regularly with assigned countries. For select markets, provide operational pricing scenario analysis on local price proposals for consultation and decision-making. Provide/withhold endorsement of product price proposals consistent with international governance at launch and any list & net price changes post-launch for assigned markets. Monitor local pricing and contracting implementation. Ensure support to countries for price certificates and other pricing-related documentation. Identify future price evolution events and ensure maintenance of these in our system for assigned countries. Leverage pricing analytics and coordinate with funds flow and finance to identify and manage non-profitable products. Enhance information exchange and best practice sharing on pricing across international functions, regions, and countries. Essential requirements: At least 5 years of relevant senior level experience at pharmaceutical companies, HTA or health care consultancy companies; pricing, access and commercial experience across multiple brands and multiple therapeutic areas. Bachelors (Masters preferred) in Math, Economics, Business Administration, Finance, Marketing, Health Policy, Health Economics, or advanced related fields. Excellent analytical skills and ability to extract and quickly process key information, summarize key needs, and provide targeted and appropriate insights and recommendations. Recent experience in above country (regional or global) role preferred. Strong external orientation with broad & deep therapeutic experience, healthcare systems and market insights. Track record of successfully working across functions (especially, Medical, Marketing, Strategy, Finance). Desirable requirements: At least 7 years of relevant senior level experience Location: This role can be based in Basel, Switzerland or can also be based in London, UK; Dublin, Ireland or Barcelona, Spain. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The *Senior/Clinical Development Director (*Sr. CDD) is the clinical/scientific expert and if assigned the clinical development lead of a section of a global clinical program and/or trial. (e.g., an indication, a new formulation, or a specific development phase) or a large, complex trial, under the leadership of the GPCH. The *Sr. CDD may be assigned to have a team leadership role for sections clinical programs and/or global clinical trials, depending on the size, nature and complexity About the Role Major accountabilities: Supports and if assigned leads delivery of all assigned clinical deliverables in the assigned section of a clinical program. Clinical deliverables may include the clinical development strategy for assigned program section(s), clinical sections of individual protocols consistent with the Integrated Development Plans (IDP), clinical data review program specific standards, clinical components of regulatory documents/registration dossiers, and publications Contributes and if assigned leads development and delivery of clinical sections of trial and program level regulatory documents (e.g., Investigator’s Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drives execution of the section of the clinical program in partnership with global line functions, in particular clinical operations, trial leaders and data management/analysis, and regional/country clinical development associates Ensures ongoing clinical and scientific review of clinical trial data. Work in close collaboration with the data management and statistics teams to ensure proper data quality and analysis of clinical trial results. May be the Program or Function Manager of associates (e.g., CDD or associate CDD Supports GPCH in assessing overall risk-benefit of the molecule for the assigned section of the clinical program, may be a (core) member of the Safety Management Team (SMT), and supports overall program safety reporting (e.g., Periodic Safety Update Reports (PSURs), Drug Safety Update Reports (DSURs), and other safety related documents) in collaboration with the medical monitor, CDMD and Patient Safety Member and if assigned may (co-)lead the Global Clinical Team (GCT), if there is a separate GCT for the assigned program section. Represents the section when assigned in Global Program Team (GPT) meetings, and as the section spokesperson in internal and external meetings/boards, as assigned Supports the Clinical Development Head (CDH) by providing clinical/scientific input into IDP/CDP and CTP reviews and contributing/driving development of disease clinical standards for new disease areas. May take on other TA responsibilities as directed by the CDH Minimum Requirements: Work Experience: Advanced degree in life sciences/healthcare (or clinically relevant degree) is required. PharmD, or PhD strongly preferred ≥ 10 years of involvement in clinical research, global drug development in an academic or industry environment spanning clinical activities in Phases I through IV. ≥ 5 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry. Experience in late phase clinical development strongly preferred Solid scientific writing skills Experience with regulatory submissions (IND, NDA/BLA, CTA/MAA) preferred Solid and advanced scientific acumen and ability to analyze and interpret scientific literature and data. Strong affinity with data, data quality and analysis. Preferred knowledge and/or experience of assigned therapeutic area Demonstrated ability to establish strong scientific partnership with key internal and external stakeholders ≥ 3 years people management experience required; this may include management in a matrix environment * Final job title Senior Clinical Development Director, Level 6 / Clinical Development Director, Level 6 and associated responsibilities will be commensurate with the successful candidates’ level of expertise. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050166 May 20, 2025 Switzerland Summary The Senior Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Sr CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 10 years of experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. - 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we-ll help you thrive personally and professionally:- Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Barcelona Gran Vía, Spain Alternative Location 2 Dublin (NOCC), Ireland Alternative Location 3 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Discovery Postdoctoral Fellow in pathogenic, innate signaling in B cells About the Role Sta About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help uncover how the transcription factor IRF5 contributes to B cell-mediated pathology in systemic autoimmune diseases. You will be part of our Innate Immunity group in Basel, CH and work together with a cross functional team. The project aims to uncover the pathogenic role of IRF5 in autoimmune diseases by interrogating its role in transcriptional regulation of key pathways and target genes in B cells employing state of the art omics technologies (CUT&RUN, transcriptomics etc.) combined with in house mouse- and primary cellular models. Available patient samples will allow the candidate to translate findings to relevant diseases. The project will take advantage of readily available key reagents, assays, infrastructure, wet lab- and computational-workflows as well as access to a broad range of expertise covering immunology, various technologies and data science. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset. E.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Lead and drive multidisciplinary projects and engage with experts from diverse departments within Biomedical Research Develop and nurture relationships with key collaborators and stakeholders Present research findings and insights at internal and external meetings Actively participate and collaborate within the BR Postdoc community Role Requirements : PhD in immunology, molecular or cellular biology or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strong expertise in innate signaling or B cell biology, and molecular biology Strong publication records or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Candidates must be able to work independently as well as with interdisciplinary teams Experience in the following would be advantageous: experience with in vivo mouse work chromatin profiling and omics experiments computational skills (R, Phyton) to analyze own datasets How to apply Please submit your CV and cover letter by July 11th, 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054185 Jun 04, 2025 Switzerland Summary Discovery Postdoctoral Fellow in pathogenic, innate signaling in B cells About the Role Sta About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help uncover how the transcription factor IRF5 contributes to B cell-mediated pathology in systemic autoimmune diseases. You will be part of our Innate Immunity group in Basel, CH and work together with a cross functional team. The project aims to uncover the pathogenic role of IRF5 in autoimmune diseases by interrogating its role in transcriptional regulation of key pathways and target genes in B cells employing state of the art omics technologies (CUT&RUN, transcriptomics etc.) combined with in house mouse- and primary cellular models. Available patient samples will allow the candidate to translate findings to relevant diseases. The project will take advantage of readily available key reagents, assays, infrastructure, wet lab- and computational-workflows as well as access to a broad range of expertise covering immunology, various technologies and data science. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset. E.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Lead and drive multidisciplinary projects and engage with experts from diverse departments within Biomedical Research Develop and nurture relationships with key collaborators and stakeholders Present research findings and insights at internal and external meetings Actively participate and collaborate within the BR Postdoc community Role Requirements : PhD in immunology, molecular or cellular biology or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strong expertise in innate signaling or B cell biology, and molecular biology Strong publication records or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Candidates must be able to work independently as well as with interdisciplinary teams Experience in the following would be advantageous: experience with in vivo mouse work chromatin profiling and omics experiments computational skills (R, Phyton) to analyze own datasets How to apply Please submit your CV and cover letter by July 11th, 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Befristet) Shift Work No

Summary Discovery Postdoctoral Fellow in Cancer Functional Genomics About the Role About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our team in the Oncology Drug Discovery (ODD) group in Basel, Switzerland. You will work on a project that aims at understanding the molecular mechanisms regulating the activity of specific lineage-specific transcription factors, and how they selectively exert their oncogenic functions. You will employ cutting-edge gene editing and functional genomics techniques to dissect the structure-function relationship of these oncogenes, how they can differently regulate transcription and respond to external stimuli in the context of cancer, and help elucidate mechanisms of resistance that may arise upon pharmacological treatment. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams, maintain timely organized records, and actively participate in lab activities. Design, execute, analyze and evaluate experiments in various in vitro and ex vivo assays. Research scientific literature, implement new technologies, and present findings within the team and the broader community. Present at internal meetings, international conferences and publish in top-tier scientific journals. Role Requirements : PhD in molecular biology, cancer biology, biochemistry or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Knowledge in gene regulation, chromatin and transcription factor biology, particularly in the context of cancer. Strong experience with molecular biology tools, gene editing (e.g. knock-in/out, base editing) and genome-wide genomics techniques (e.g. ChIP-seq, ATAC-seq) Expertise in large-scale functional genomics screens (e.g. CRISPR screen, Perturb-seq, deep mutational scanning) Bioinformatics skills are beneficial. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV (with contact for three referees) and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054303 Jun 05, 2025 Switzerland Summary Discovery Postdoctoral Fellow in Cancer Functional Genomics About the Role About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our team in the Oncology Drug Discovery (ODD) group in Basel, Switzerland. You will work on a project that aims at understanding the molecular mechanisms regulating the activity of specific lineage-specific transcription factors, and how they selectively exert their oncogenic functions. You will employ cutting-edge gene editing and functional genomics techniques to dissect the structure-function relationship of these oncogenes, how they can differently regulate transcription and respond to external stimuli in the context of cancer, and help elucidate mechanisms of resistance that may arise upon pharmacological treatment. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Preferred start date: October 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams, maintain timely organized records, and actively participate in lab activities. Design, execute, analyze and evaluate experiments in various in vitro and ex vivo assays. Research scientific literature, implement new technologies, and present findings within the team and the broader community. Present at internal meetings, international conferences and publish in top-tier scientific journals. Role Requirements : PhD in molecular biology, cancer biology, biochemistry or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Knowledge in gene regulation, chromatin and transcription factor biology, particularly in the context of cancer. Strong experience with molecular biology tools, gene editing (e.g. knock-in/out, base editing) and genome-wide genomics techniques (e.g. ChIP-seq, ATAC-seq) Expertise in large-scale functional genomics screens (e.g. CRISPR screen, Perturb-seq, deep mutational scanning) Bioinformatics skills are beneficial. Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV (with contact for three referees) and cover letter by July 1st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary In close coordination with the respective BD&L Partnering Therapeutic Area Head, negotiate and secure BD&L deals of a specific therapeutic area (i.e. Immunology) across all stages of development (from research to commercial stage) and geographies. Act as the deal architect and lead negotiator (deal structuring, term sheet, contract negotiations) for partnering opportunities strategically aligned with growth initiatives. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities: Provide outstanding partnering and project management through the entire deal making process to secure and implement attractive deals Develop partnering structures tailored to the profile of each envisioned collaboration Propose deal terms and negotiation strategy to BD&L Partnering Head(s) Drive contribution from various Functions to develop robust and comprehensive business cases and derive clear recommendations Identify and resolve issues promptly, gather and analyze information skillfully, escalate to senior management quickly Work closely with the Therapeutic Area Leadership team (Research, Development, Commercial, Strategy Heads) to understand key partnering priorities, drive alignment, and proactively communicate project updates Facilitate decision making process at key governance deal committees by preparing comprehensive presentations/memos Proactively monitor the external business environment and maintain a knowledge base of licensing transactions and other companies partnering activities Build and continuously strengthen broad industry network to facilitate deal making Essential Requirements: Relevant degree, Ph.D. or Advanced degree desirable in the biological science plus MBA or similar advanced degree. Proficiency in English required - verbal, written, and negotiation. Demonstrated industry experience with significant experience in Business Development or Investment Banking Proven track record at sourcing, structuring, negotiating, closing different type of partnerships. Broad network in the industry Demonstrated history of leading international, global, and cross-functional teams and strategic corporate initiatives. Deal sheets are required as part of your application. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role We are thrilled to seek applications for our Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program. This applied research program is designed to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a fellow, you will learn to apply your quantitative and computational skills to make a difference for patients and reimagine medicine at Novartis. As part of the Data Science Innovation Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program has a duration of 3 years. Drug hunting is a team sport, and you will gain experience in Data Science & AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Seize this chance to be at the forefront of Data Science and AI, and shape the future of drug discovery! This project aims to perform human genetics-driven target discovery for immunological diseases. The successful candidate will establish a pipeline of statistical and machine learning models to identify causal variants, map them to likely target genes, and describe potential underlying mechanisms. We will apply this pipeline to immune system-driven diseases to formulate clear hypotheses on novel drug targets and test them experimentally. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Location: Campus Basel, Switzerland Key responsibilities As a Data Science Innovation Postdoctoral Fellow, you will: Work independently as well as within interdisciplinary teams to drive your project Analysis, integration, and visualization of human genetics with complementary omics data Apply statistical and machine/deep learning methods to identify disease associated variants, their target genes and regulatory mechanism Analyze omics datasets to formulate and/or support hypotheses generated by ML models Effectively collaborate with wet lab scientists to validate in silico findings Role requirements : PhD in Genetics, Computational Biology or a related field (Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD, i.e. PhD degrees must have been awarded May 2023 or later). Excellent skills in computational and statistical analysis of genetics and omics data (GWAS, QTLS, transcriptomics and chromatin omics) Excellent skills in programming, data visualization and reproducible research in R/Bioconductor and/or Python Experience with machine/deep learning methods is considered a plus Experience in Immunology is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity #DSIF How to apply Please submit your CV and cover letter by July 15st 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are seeking a motivated QC-Analyst for Biopharmaceutical Production within the framework of raw materials, drug substance, and in-process controls. The candidate will perform analytical testing and ensure compliance with SOPs, analytical methods, and compendial standards. About the Role Major accountabilities: · Conduct and coordinate quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements · Independent planning, implementation, and evaluation of routine and special analyses in a GMP-regulated environment · Interpret test data, prepare detailed reports, and maintain accurate record of test results. · Troubleshoot testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis · Conducting microbiological tests such as total germ count determinations (MET) and bacterial endotoxins (BET) · Participate in the validation of analytical procedures · Collaborate closely with the internal teams to optimize quality control processes · Instrument responsibilities, including qualification, maintenance, and calibration documentation · Support in ensuring that the laboratory is maintained in a ready state of inspection. Key performance indicators: · Timely test record completion and accurate processing without delays · Prompt reporting of missed deadlines and aim for shortest possible lead times · Continuous readiness for inspection · Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities · Proactively identify and implement cost-reducing optimizations · Complete all assigned training as per the provided plan Minimum Requirements: · Completed scientific education (e.g., Laboratory Technician, Bachelor or Master) · Practical experience in a GMP-regulated lab and document creation · Knowledge in common analysis techniques, especially HPLC and photometry; microbiological knowledge is an advantage · Working experience in laboratory environment in the pharmaceutical industry · Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage · Ability to work precisely, independently, and proactively · Reliability, flexibility, resilience, and strong teamwork skills · Shift work with normal working times (one shift) including weekends Skills: · Continuous learning · Dealing with ambiguity · Decision making · GMP · Industry standards · Laboratory equipment · Laboratory excellence · Quality Control (QC) testing · Quality Control sampling · Self awareness · Technological expertise Languages : · Fluent in German (spoken and written) and proficient in English Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you someone who can display creativity in the field of analytical science & technology - with an interest in analytical lifecycle management? As a Senior QC Specialist in ChemOps you will have a leading role in driving current and future analytical control strategies for new chemical entities (including oligonucleotide projects) ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Major accountabilities: Analytical project lead for launch and lifecycle management of projects in collaboration with multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Inspire analytical and process innovation. Drive and implement the improvement of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Apply your knowledge and expertise by providing training and mentoring to empower colleagues. Education: MSc or PhD in analytical chemistry, organic chemistry or related field + 5 years industry experience Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people’s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities – all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and join us in reimagining new medicines together! The Role: As Global Program Regulatory Director, you will provide global leadership throughout the lifecycle of a development and/or marketed product program(s). Your experience will ensure that input from global HAs, regional and functional collaborators is collated to build a coherent, global regulatory strategy which fulfills the target product profile and portfolio objectives. You will also be responsible for identifying regulatory opportunities, mitigate against potential issues and ensure the execution of regulatory strategy across regions. In addition, you will lead global regulatory sub- team(s), share your regulatory and development expertise, and represent the RA function on cross functional initiatives and committees. About the Role Major accountabilities: Regulatory Strategy & Submissions With multiple stakeholders, develop, document and communicate high quality global regulatory strategies and HA interactions to achieve business objectives. Evaluate and communicate potential global regulatory opportunities and risks, developing mitigation strategies Leverage regional expertise in executing global regulatory strategy, and HA engagement. Provide strategic regulatory input into analysis and interpretation of scientific data, to key documentation, Leverage scientific knowledge and acumen in the analysis, interpretation and communication of data to colleagues. Lead interactions with Regulatory Affairs and Development Unit management and external consultants, for input to regulatory strategies. Accountable , in conjunction (with regulatory labelling) for maintaining Novartis core product information documents though product life cycle. Contribute to any BD&L Due Diligence activity Regulatory Excellence & Compliance Ensure compliance with global regulatory requirements and adherence to regulatory internal policies and processes, coordinating regulatory compliance activities at a global level. Provide support as needed for non-project related excellence activities. People As an effective matrix leader, provide feedback and mentor team members, line functions and sub- teams. Working with line managers, you will provide opportunities for team member growth and development, leading by example acting as a role model for Novartis values and behaviours. Your Experience: Science based bachelor's or master's degree. Advanced degree desirable. Significant regulatory and pharmaceutical development experience, across Phases I-IV. A track record of working with HA guidance and feedback, discussion and negotiations; post marketing/ brand optimization strategies and regulatory operations. Proven leadership success across a broad range of regulatory and pharmaceutical development activities. Strong interpersonal skills and experience working in a complex, cross functional organization, navigating complexity and leading cross function teams. Fluency in English. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050556 May 08, 2025 Switzerland Summary Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people-s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities - all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and join us in reimagining new medicines together! The Role: As Global Program Regulatory Director, you will provide global leadership throughout the lifecycle of a development and/or marketed product program(s). Your experience will ensure that input from global HAs, regional and functional collaborators is collated to build a coherent, global regulatory strategy which fulfills the target product profile and portfolio objectives. You will also be responsible for identifying regulatory opportunities, mitigate against potential issues and ensure the execution of regulatory strategy across regions. In addition, you will lead global regulatory sub- team(s), share your regulatory and development expertise, and represent the RA function on cross functional initiatives and committees. About the Role Major accountabilities: Regulatory Strategy & Submissions With multiple stakeholders, develop, document and communicate high quality global regulatory strategies and HA interactions to achieve business objectives. Evaluate and communicate potential global regulatory opportunities and risks, developing mitigation strategies Leverage regional expertise in executing global regulatory strategy, and HA engagement. Provide strategic regulatory input into analysis and interpretation of scientific data, to key documentation, Leverage scientific knowledge and acumen in the analysis, interpretation and communication of data to colleagues. Lead interactions with Regulatory Affairs and Development Unit management and external consultants, for input to regulatory strategies. Accountable, in conjunction (with regulatory labelling) for maintaining Novartis core product information documents though product life cycle. Contribute to any BD&L Due Diligence activity Regulatory Excellence & Compliance Ensure compliance with global regulatory requirements and adherence to regulatory internal policies and processes, coordinating regulatory compliance activities at a global level. Provide support as needed for non-project related excellence activities. People As an effective matrix leader, provide feedback and mentor team members, line functions and sub- teams. Working with line managers, you will provide opportunities for team member growth and development, leading by example acting as a role model for Novartis values and behaviours. Your Experience: Science based bachelor's or master's degree. Advanced degree desirable. Significant regulatory and pharmaceutical development experience, across Phases I-IV. A track record of working with HA guidance and feedback, discussion and negotiations; post marketing/ brand optimization strategies and regulatory operations. Proven leadership success across a broad range of regulatory and pharmaceutical development activities. Strong interpersonal skills and experience working in a complex, cross functional organization, navigating complexity and leading cross function teams. Fluency in English. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10040975 May 06, 2025 Switzerland Summary Location: Basel, Switzerland; Responsible for timely, independent management of complex intellectual property (IP) administrative, filing and legal support tasks. Proactive involvement in a high performing team providing a diverse range of complex IP administrative support for a defined group of patent practitioners in regional, international and foreign filing. Maintain and manage a complex, accurate docket, using a patent docketing system. Provides expert knowledge and understanding of IP law and practice issues. Undertakes operational and strategic responsibilities to maximize the effectiveness of paralegal sup-port at a local and global level. Responsible for applying, maintaining and contributing to the improvement of the department best practices. Responsible for training others in all areas of European Patents (EP) and foreign patent matters. Lead teams within the Patent Support team in areas of efficiency and improvement of current processes About the Role Your responsibilities include, but not limited to : Filing of EP/international and foreign patent applications and related correspondence from filing to issuance of grant. Responsible for EP and international patent filings, patent nationalizations into foreign jurisdictions, as well as foreign filings under other conventions. Responsible for preparing all documents required in connection with EP, Patent Cooperation Treaty (PCT) and foreign applications; proactively initiates preparation of responses to official communications and notifications. Maintain and share advanced knowledge of latest patent rules and adapting practices to comply. Monitor and updating electronic docket(s) for responsible attorney(s) and assigned paralegal tasks on a daily basis. Monitor all assigned cases and proactively ensuring that all related deadlines are met in a timely manner. Independent, proactive and critical review, maintenance and assistance of responsible attorney(s)- dockets and workload. Coordinate outsourcing, transfer in and transfer out of patent files and responsibilities in a timely and efficient manner, minimizing risk of loss of rights. Communicate effectively with colleagues, inventors, foreign agents and other associates. Actively participate in patent group and cross-divisional meetings as needed. Role includes on an as needed basis the flexibility to provide support in other areas within the Patent Support team (i.e. annuities, invoicing and data input). Undertake projects to address global prosecution and operational issues affecting department. Leads teams in development of procedures and processes. Ability to conduct meetings as needed. Recommends areas/systems of possible improvement in efficiencies in procedures. What you'll bring to the role: Relevant degree, Law - Paralegal/equivalent IP certification or equivalent experience Proficiency in English required - spoken & written, other languages is an asset. Demonstrated professional experience as a patent paralegal in a patent law firm or corporation with international and foreign filing experience. Ability to deal with a highly complex environment - manages workload and work product with high quality. Advanced knowledge and competency of patent database and report generating tools. Ability to work well and meet deadlines, without supervision, in an electronic office environment. Well-developed research and critical thinking skills, and sound decision-making abilities, with attention to detail to produce consistently accurate work Excellent analytical skills, organizational, and communication skills. Liaise with other cross-divisional groups to prevent duplication of effort and to ensure that effective knowledge sharing occurs. Demonstrates leadership qualities and ability to mentor and develop the technical competence of other paralegals. Ability to act as a champion for the Patent Support team at a NIBR site. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Novartis Research & Development and Innovative Medicines Legal Teams are looking for university graduates for legal traineeships in the Global and Swiss legal departments in Basel. Duration: 6 months Start date: as of January 1, 2026 (latest start date June 1, 2026) About the Role Novartis provides healthcare solutions that address the evolving needs of patients and societies worldwide. Our mission is to discover new ways to improve and extend people’s lives. Our Novartis Research & Development and Innovative Medicines Legal Teams is looking for university graduates for a legal traineeship (Volontariat) within the Global and Swiss legal departments in Basel. The traineeship offers an excellent opportunity for you to gain practical experience in a large international pharmaceutical corporation. Are you interested in getting insights into an in-house legal department, work with experts and support our mission to reimagine medicine? We are looking forward to your application. Duration: 6 months Start date: as of January 1, 2026 (latest start date June 1, 2026) Your responsibilities include, but are not limited to: • Working on a wide range of legal matters and projects in areas such as pharmaceutical/healthcare laws, contract law, commercial law, licensing and transactions, anti-trust law; • Advising in a diverse range of development, regulatory, digital and commercial matters relating to the research & development and commercialization of pharmaceutical products; • Legal research and drafting documents on various legal issues and disputes in private and public law areas; • Drafting, negotiation and review of a variety of agreements (such as licensing, research collaboration, distribution, confidentiality, service, consultancy contracts); • Providing legal support for various projects, e.g. contract templates, legal trainings, global guidelines and policies, research collaborations and partnerships, etc., and interact with Novartis global, regional and country legal and business stakeholders. What you’ll bring to the role: • Education: Swiss Bachelor of Law (BLaw) degree or Master of Law (MLaw) degree or equivalent from a Swiss university • Languages: Good German and English skills • Experience/Professional requirements: Ideally, you have already gained your first professional or internship experience. Potential candidates should have an interest in legal issues in a major international pharmaceutical corporation, pronounced commitment and the will and motivation to discover and learn new things. Please submit a cover letter that includes your motivation for the position and from when you will be available. Thank you. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a Postdoc in bioprocess modelling and new technologies, you will be a key enabler for our aspirations to advance on the field of model-based development and optimization, as well as contribute to our innovation strategy. You will function as subject matter expert on in-silico modelling, data, and digital initiatives in close collaboration with experts within the Biologics community. About the Role Preferred start date : August 2025 Duration: 2 years Location: Campus Basel Your Responsibilities: Your responsibilities include, but are not limited to: Develop mathematical models (mechanistic, data-driven, hybrid) to characterize the production system (cellular, USP or DSP units, etc.) and its dynamic including uncertainty modeling. Design experiments in the context of model-based experimental learning to support the model development activities. Perform model verification and validation activities including historical and new data and convert model outcomes into practical relevant information for the purpose of process optimization/characterization. Identify and influence model-based and data driven initiatives. Contribute and function as a subject matter expert to the establishment of in-silico models in accordance with our data & digital strategy. Be proactively identifying challenges, proposing solutions, and communicating key issues to internal customers and partners. Align and collaborate with external vendors (if needed) to establish and implement innovative model-based solutions. What you will bring to the role: A PhD in relevant fields such as bio-chemical engineering, bioprocess technology, applied data science or similar with a strong background on process modelling (mechanistic, statistic and hybrid models) and optimization. Demonstrated programming skills (Python, R, and/or MATLAB), and knowledge of Machine Learning algorithms. Knowledge of USP/DSP (continuous/connected) processes, with the interest and ability to work on either field. Excellent ability to build collaborative relationships and a can-do mindset. Effective communication and presentation skills Proven ability to manage and prioritize multiple tasks. Agility to adjust to a fast-changing working environment. Proficiency in oral and written English Desirable requirements: Curious mindset with a strong interest in new technologies Attitude to resolve challenges with the ability to accurately balance between efforts, risks, and benefits. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: As a Formulation Project Leader in Oral Late Phase Development (NCE), you will lead and manage formulation and process development of Oral solid dosage forms from Lab-scale through scale-up and transfer to commercial scale in close collaboration with the Drug Product Subteam. Development activities include among others: formulation and process design and optimization, quality risk management as well as scientific writing of development documents and GMP documentation. For this position, special emphasis lies in bringing a keen interest and experience in applied data science and mechanistic modelling as tools to enable data-driven and efficient process development and scale-up. About the Role Your responsibilities will include but are not limited to: You have a passion for innovative formulations and technologies and bring experience in enabling formulation development. You understand the value and ideally bring experience of applying data-centric, computational models to guide formulation and manufacturing process development. You drive with scientific excellence the formulation development and manufacturing work of standard and enabling formulations and manufacturing processes of Oral Drug Products (NCE), supported by data-driven conclusions and mechanistic modelling. You collaborate closely with the Drug Product Sub-Team and Transfer Team members and together identify, understand and manage critical aspects concerning Drug Substance, Drug Product, Analytics, Packaging and Device. You maintain a regular exchange with key experts in e.g., Technology Focus Groups, Modelling & Simulation, Biopharmaceutics and further networks, and build their guidance into the development strategy and project plans. You author sound scientific and well-structured development documents as well as GMP documents to enable commercial manufacturing of new Drug Products. You contribute to the generation of CMC submission dossiers, support and answer Drug Product related questions of Health Authorities and Inspectors. What you’ll bring to the role: Advanced degree (minimum PhD) in relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 2 years of successful industry experience in the development of pharmaceutical formulations. Focus: Formulation and process development of standard and enabling formulations for small molecules (NCE) and scale up of manufacturing processes into oral drug products for commercialization. Knowledge of data science and data visualization, ideally experience of applying data-centric, computational models to guide formulation and manufacturing process development. Interdisciplinary thinking and interest in collaboration with other functions Broad and profound understanding of formulation development activities. Good knowledge of laboratory and/or technical tools (e.g., QbD, PAT) as well as knowledge of relevant GLP, GMP regulations and policies. Successfully demonstrated track record of creativity and problem solving in projects. Effective communication, organizational, planning and negotiation skills. Scientific and technical writing skills Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize on sharing our enterprise strategies while remaining focused on addressing the unique country’s needs as a value-added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio. Our International HEOR & PCO team holds an important role within the International Value & Access organization, leading the evidence generation to demonstrate the value of Novartis innovative medicine portfolio. As a member of the International HEOR & PCO Leadership Team, you will be in the driver seat for team development, leading HEOR innovations and HTA preparation within one of our four Therapeutic Areas. We are looking for a dynamic and inventive leader who is collaborative and wants to make an impact. Lead a team of HEOR professionals, strategically and operationally, across the R-D-C continuum, working closely with the designated TAs (Cardio-Renal-Metabolic, Immunology, Oncology, and Neurosciences) within International Value & Access, International CLS, and International Medical Affairs, and across global functional partners in Research, Development, Medical Affairs, S&G and with our Regions and Countries / HTA Markets. About the Role Key Responsibilities: Lead an HEOR TA team and inspire the wider HEOR community to attract and retain talent development, and ensuring impactful value evidence strategy aligned with the market access, commercial and medical strategies. Develop and deliver all aspects of HEOR & HTA strategy and plans for prioritized Novartis as-sets, within the TA with internal and external stakeholders at all stages of the R-D-C continuum. Ensure impactful, timely delivery of critical HEOR deliverables (including GVD, models, evidence synthesis, ITCs, Patient Preference, RWE & OR, HTA submissions incl. EU HTA JCA, access-enabling studies, etc.). In partnership with the HTA Strategy Innovation drives HEOR TA readiness and preparation for International HTA adoption incl. EU HTA implementation by preparing and leading the EU HTA Joint Clinical Assessment (JCAs) submissions, EU HTA Joint Scientific Consultations (JSC) and early HTA advice needed for the assets, with internal partners Market Access, HTA Policy, the TAs, Medical Affairs, Development, Patient Engagement, AQS Biostats, Regions, Key HTA Countries). Collaborate with Market Access, Medical, S&G and Development colleagues to ensure full integration of HEOR/evidence strategy in HTAP (Health Technology Assessment Strategy Plan) in-to Integrated Evidence Strategy (IEP), Integrated Product Access Strategy (IPAS) and One Brand Plan (1BP). Co-create IEP with medical affairs and development, and ensure HTA, payer and HCS needs i.e. PICO are reflected in clinical trial designs, CDP, TPP, and other relevant enterprise deliverables. Oversee the delivery of evidence required by country teams in prioritized markets to achieve reimbursement and other positive funding recommendations and optimal access. Works closely with the Head, International HEOR & PCO and HEOR TAs to flex resources across the R-D-C continuum aligned with TA business and disease area priorities and develop and improve new ways of working where needed, in partnership with the Head International HEOR & PCO and relevant functions, with a focus on efficiency and impact. Facilitate shared learnings and hands-on utilization of HEOR deliverables and evidence throughout the organization. Stay abreast of internal and external developments, trends and other dynamics that affect the HEOR and HTA domain and share learnings with team and the broader organization. Externally with HTA agencies, policy makers, regulatory agencies, HEOR scientific groups and others to shape methods, HTA policies, and ensure evidence-based value-demonstration and decision making, and inform the organization on opportunities and risks. Essential requirements: 8+ years of relevant HEOR-related experience 10+ years of pharmaceutical industry experience Advanced Degree in Health Economics, Epidemiology, Statistics or a related field Significant global and/or regional experience and/or CPO experience Subject matter expertise in the areas of HEOR and other approaches to value demonstration Considerable experience planning, creating, analyzing and publishing impactful HEOR data/RWD Proven capability in designing impactful HEOR/PCO, RWE and/or clinical studies for market access. Proven capability to deploy HEOR methods to support pricing proposals Strong knowledge of research methodology and statistical methods. Ability to collaborate with quantitative scientists and external thought-leaders Desirable requirements: Significant experience working across the drug development continuum, early through post-launch. HEOR or other evidence generation experience with Top HTA countries An active external network with HEOR, RWE, HTA, and health policy thought leaders. Patient-centric mindset and passion for delivering value for Payers and Healthcare systems. Ability to influence CDPs or IEPs to meet the needs of payers or other HCS decision makers. Successful track record managing HEOR teams and people development Location: This role can be based in the UK, London but can also based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 About the Role Are you interested in pursuing a career in law? We have the perfect opportunity for you! Our legal trainee position offers excellent hands-on, in-house legal experience within the dynamic and multinational environment of a leading pharmaceutical company. More than 70’000 unique individuals work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world. We are seeking a motivated and diligent legal trainee who has the courage to navigate in unknown and ambiguous legal areas and has the curiosity to learn and being exposed to interesting and challenging new legal questions. If you're passionate about making a difference and keen to kickstart your career with our in-house team, this could be the ideal role for you. We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 Your responsibilities include: • You'll be the backbone of our Legal team, offering essential advice in employment law (including questions related to Diversity, Equity & Inclusion), as well as litigation and investigation. You'll have the opportunity to tackle complex global and local issues, transforming challenges into solutions. • You'll get your hands on practical tasks, managing individual legal cases, but also major projects (reorganizations, divestments, implementation of new policies and processes, etc.), drafting and reviewing agreements, internal regulations, and templates. This is your chance to shift from theory to practical application, making an immediate impact. • Your role will involve in-depth legal research and the creation of legal memoranda, helping us to break down complex ideas into digestible insights. Here, your knowledge will fuel our mutual success. • You'll also play a pivotal role in reporting key legal matters to our audit committees in strict adherence to the Sarbanes-Oxley Act. What you’ll bring to the role: • Swiss Bachelor of Law (BLaw) und Master of Law (MLaw) • Excellent proficiency in English and German, both in verbal and written communication • High motivation and ability to work independently on challenging tasks and projects • Prior legal internship and knowledge in employment law is a plus Are you ready to sharpen your skills and inspire change? If you're excited to contribute and learn, apply now, and submit a cover letter that includes your motivation for the position and your availability for six months starting in January or June 2026. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10043484 May 13, 2025 Switzerland Summary Location: Basel, Switzerland Fulltime, onsite, #LIonsite We are seeking a highly motivated and curious Principal Scientist whose focus will be on siRNA discovery in the xRNA Team within Biomedical Research based in Basel. The team develops next-generation xRNA therapeutics in a collaborative and innovation driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have strong experience in siRNA biology and/or therapeutics and will have a key role in driving the development of the xRNA platform and mentoring Lab team members. About the Role Key Responsibilities: Lead matrix-oriented platform teams for the development of siRNA therapeutics Experience with end-to-end NGS experiments including library preparation, sequencing, and analysis Drive innovation based on data mining form hypothesis generation to conduct studies in a collaborative environment across Biomedical Research Design, plan and supervise siRNA cell-based screening activities Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation With supervision lead junior scientists in the lab and with data analysis Represent xRNA team on cross-functional project teams to advance siRNA programs through the development pipeline Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner Role Requirements: PhD in biochemistry or biology or related scientific discipline 3 - 5 years of post-PhD research experience gained in academia as a Postdoc and/or in industry Research experience in siRNA biology. Knowledge of siRNA therapeutics would be an advantage. Strong genomics background with expertise in RNA-Seq from experiment to data processing Able to run R scripts independently Expertise in mammalian cell culture from immortalized to primary cells Experience with cross functional teams and ability to serve as a point of contact for the team with minimal supervision Strong multi-tasking, organizational, attention to detail, verbal/written communication skills Ability to collaborate and thrive in fast-paced, team-oriented environment Desired Requirements: Expertise with BioMek or Opentrons liquid handlers Proficient in R and/or Python. Machine Learning experience a plus. *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated and curious lab-based Senior Scientist I whose focus will be on siRNA discovery in the xRNA Team within Biomedical Research in Basel. The team develops next-generation xRNA therapeutics in a collaborative and innovation driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have a background in biology research with ideally a focus in RNA biology. The ideal candidate will have strong experience in medium – to high throughput screening using automation, cell culture techniques, assay development and technologies such as liquid handlers. About the Role Key Responsibilities: Design, plan and conduct routine siRNA screening in cell-based transfection assays using qPCR and reporter-based systems Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation Contribute to designing, and developing automated workflows Operate automated liquid handling robotics platform Work collaboratively in a matrix-oriented environment and present work on a regular basis in unit meetings Acting as a point-of-contact in the team of day to day activities Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner Role Requirements: A higher degree in biology (such as Bachelor’s or Master’s), or Apprenticeship with equivalent industry experience in biochemistry, cell biology or related scientific discipline A minimum of 5 years of research experience gained ideally in a lab environment in a pharma and/or biotech industry setting Expertise in cell culture and conducting expression read outs (e.g. qPCR, Western Blot, ELISA) Experience with liquid handlers and automation of cell based assays Strong competence in MS office applications, expertise in Excel and maintenance of electronic Lab Notebooks Strong multi-tasking, organizational, attention to detail, verbal/written communication skills Ability to collaborate and thrive in fast-paced, team-oriented environment Desired Requirements: Primary cell culture experience Expertise in Spotfire and/or GraphPad PRISM Expertise with BioMek or Opentrons liquid handlers *Restrictions on flexible working may apply and are discretionary and can be discussed at interview, if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051591 May 12, 2025 Switzerland Summary We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 About the Role Are you interested in pursuing a career in law? We have the perfect opportunity for you! Our legal trainee position offers excellent hands-on, in-house legal experience within the dynamic and multinational environment of a leading pharmaceutical company. More than 70-000 unique individuals work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world. We are seeking a motivated and diligent legal trainee who has the courage to navigate in unknown and ambiguous legal areas and has the curiosity to learn and being exposed to interesting and challenging new legal questions.If you're passionate about making a difference and keen to kickstart your career with our in-house team, this could be the ideal role for you. We offer two 6-month legal traineeship positions, starting January 1, 2026 and June 1, 2026 Your responsibilities include: You'll be the backbone of our Legal team, offering essential advice in employment law (including questions related to Diversity, Equity & Inclusion), as well as litigation and investigation. You'll have the opportunity to tackle complex global and local issues, transforming challenges into solutions. You'll get your hands on practical tasks, managing individual legal cases, but also major projects (reorganizations, divestments, implementation of new policies and processes, etc.), drafting and reviewing agreements, internal regulations, and templates. This is your chance to shift from theory to practical application, making an immediate impact. Your role will involve in-depth legal research and the creation of legal memoranda, helping us to break down complex ideas into digestible insights. Here, your knowledge will fuel our mutual success. You'll also play a pivotal role in reporting key legal matters to our audit committees in strict adherence to the Sarbanes-Oxley Act. What you-ll bring to the role: Swiss Bachelor of Law (BLaw) und Master of Law (MLaw) Excellent proficiency in English and German, both in verbal and written communication High motivation andability to work independentlyon challenging tasks and projects Prior legal internship and knowledge in employment law is a plus Are you ready to sharpen your skills and inspire change? If you're excited to contribute and learn, apply now, and submit a cover letter that includes your motivation for the position and your availability for six months starting in January or June 2026. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com, and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Others Job Type Full time Employment Type Early Career (Befristet) Shift Work No

Job ID REQ-10048565 May 08, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: As a Formulation Project Leader in Oral Late Phase Development (NCE), you will lead and manage formulation and process development of Oral solid dosage forms from Lab-scale through scale-up and transfer to commercial scale in close collaboration with the Drug Product Subteam. Development activities include among others: formulation and process design and optimization, quality risk management as well as scientific writing of development documents and GMP documentation. For this position, special emphasis lies in bringing a keen interest and experience in applied data science and mechanistic modelling as tools to enable data-driven and efficient process development and scale-up. About the Role Your responsibilities will include but are not limited to: You have a passion for innovative formulations and technologies and bring experience in enabling formulation development. You understand the value and ideally bring experience of applying data-centric, computational models to guide formulation and manufacturing process development. You drive with scientific excellence the formulation development and manufacturing work of standard and enabling formulations and manufacturing processes of Oral Drug Products (NCE), supported by data-driven conclusions and mechanistic modelling. You collaborate closely with the Drug Product Sub-Team and Transfer Team members and together identify, understand and manage critical aspects concerning Drug Substance, Drug Product, Analytics, Packaging and Device. You maintain a regular exchange with key experts in e.g., Technology Focus Groups, Modelling & Simulation, Biopharmaceutics and further networks, and build their guidance into the development strategy and project plans. You author sound scientific and well-structured development documents as well as GMP documents to enable commercial manufacturing of new Drug Products. You contribute to the generation of CMC submission dossiers, support and answer Drug Product related questions of Health Authorities and Inspectors. What you-ll bring to the role: Advanced degree (minimum PhD) in relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 2 years of successful industry experience in the development of pharmaceutical formulations. Focus: Formulation and process development of standard and enabling formulations for small molecules (NCE) and scale up of manufacturing processes into oral drug products for commercialization. Knowledge of data science and data visualization, ideally experience of applying data-centric, computational models to guide formulation and manufacturing process development. Interdisciplinary thinking and interest in collaboration with other functions Broad and profound understanding of formulation development activities. Good knowledge of laboratory and/or technical tools (e.g., QbD, PAT) as well as knowledge of relevant GLP, GMP regulations and policies. Successfully demonstrated track record of creativity and problem solving in projects. Effective communication, organizational, planning and negotiation skills. Scientific and technical writing skills Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Fulltime, onsite, #LIonsite We are seeking a highly motivated and curious Principal Scientist whose focus will be on siRNA discovery in the xRNA Team within Biomedical Research based in Basel. The team develops next-generation xRNA therapeutics in a collaborative and innovation driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have strong experience in siRNA biology and/or therapeutics and will have a key role in driving the development of the xRNA platform and mentoring Lab team members. About the Role Key Responsibilities: Lead matrix-oriented platform teams for the development of siRNA therapeutics Experience with end-to-end NGS experiments including library preparation, sequencing, and analysis Drive innovation based on data mining form hypothesis generation to conduct studies in a collaborative environment across Biomedical Research Design, plan and supervise siRNA cell-based screening activities Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation With supervision lead junior scientists in the lab and with data analysis Represent xRNA team on cross-functional project teams to advance siRNA programs through the development pipeline Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner Role Requirements: PhD in biochemistry or biology or related scientific discipline 3 - 5 years of post-PhD research experience gained in academia as a Postdoc and/or in industry Research experience in siRNA biology. Knowledge of siRNA therapeutics would be an advantage. Strong genomics background with expertise in RNA-Seq from experiment to data processing Able to run R scripts independently Expertise in mammalian cell culture from immortalized to primary cells Experience with cross functional teams and ability to serve as a point of contact for the team with minimal supervision Strong multi-tasking, organizational, attention to detail, verbal/written communication skills Ability to collaborate and thrive in fast-paced, team-oriented environment Desired Requirements: Expertise with BioMek or Opentrons liquid handlers Proficient in R and/or Python. Machine Learning experience a plus. *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050374 Apr 29, 2025 Switzerland Summary Job Description Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite 6000! That-s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. Global Discovery Chemistry is seeking a passionate, creative PhD level medicinal chemist to complement our nucleotide and siRNA chemistry team in Basel. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs. Please note that we have the option to hire someone at a Principal Scientist level if this role level is a better match to the experience and skill set of the applicant. About the Role Your responsibilities will include, but are not limited to: Work highly collaboratively in a multidisciplinary project team to discover and develop novel oligonucleotide therapies across various disease areas. Lead a team of scientists dedicated to design and synthesize new nucleotide building blocks, linkers, backbones from small to medium scale Intellectually contribute to and own the success of assigned projects. Together with project teams, contribute experimentally and intellectually to conceive, implement and explore innovative siRNA chemistries to address key scientific questions and ensure their smooth transition to development Lead siRNA drug discovery projects in partnership with leaders from other functions Review and critically analyse data from projects using state-of-the-art data analysis and digital tools, to identify complex problems, develop scientific hypotheses, and design molecules. Drive innovation for the establishment of new projects, including the development of exploratory projects portfolio, innovative drug discovery solutions, and evaluation of new technologies in the RNA therapeutics space. This also involves collaborating with internal and external partners around the world to progress our projects. Document and communicate results and scientific findings to internal and external audiences, in patent filings or scientific publications as appropriate Support and develop team members by sharing your know-how and hands-on experience across your work environment Provide mentoring to scientists and lead through coaching and development of scientists, independent of reporting line and/or group affiliation, to increase their impact on projects. What you will bring to the role: A PhD degree with a focus on synthesis and design of oligonucleotides. Demonstrated practical knowledge in medicinal chemistry with focus on oligo/nucleotides for 8+ years with a track record of deliverables. Experience in solid phase oligonucleotide synthesis is considered a plus A track record of people leadership and development skills A mind-set of curiosity and openness to diverse thinking, with an enthusiasm to develop yourself and others Innovative and independent problem-solving skills Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery Aptitude to work in a fast-paced team-oriented matrix environment Excellent written and verbal communication and strong influencing skills, with an ability to present and discuss project strategies and challenges Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Job Description Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite 6000! That’s the number of associates in the Novartis BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. Global Discovery Chemistry is seeking a passionate, creative PhD level medicinal chemist to complement our nucleotide and siRNA chemistry team in Basel. You will work highly collaboratively in a multidisciplinary environment at the interface between research and development to discover and develop novel siRNA therapies for high unmet medical needs. Please note that we have the option to hire someone at a Principal Scientist level if this role level is a better match to the experience and skill set of the applicant. About the Role Your responsibilities will include, but are not limited to: Work highly collaboratively in a multidisciplinary project team to discover and develop novel oligonucleotide therapies across various disease areas. Lead a team of scientists dedicated to design and synthesize new nucleotide building blocks, linkers, backbones from small to medium scale Intellectually contribute to and own the success of assigned projects. Together with project teams, contribute experimentally and intellectually to conceive, implement and explore innovative siRNA chemistries to address key scientific questions and ensure their smooth transition to development Lead siRNA drug discovery projects in partnership with leaders from other functions Review and critically analyse data from projects using state-of-the-art data analysis and digital tools, to identify complex problems, develop scientific hypotheses, and design molecules. Drive innovation for the establishment of new projects, including the development of exploratory projects portfolio, innovative drug discovery solutions, and evaluation of new technologies in the RNA therapeutics space. This also involves collaborating with internal and external partners around the world to progress our projects. Document and communicate results and scientific findings to internal and external audiences, in patent filings or scientific publications as appropriate Support and develop team members by sharing your know-how and hands-on experience across your work environment Provide mentoring to scientists and lead through coaching and development of scientists, independent of reporting line and/or group affiliation, to increase their impact on projects. What you will bring to the role: A PhD degree with a focus on synthesis and design of oligonucleotides. Demonstrated practical knowledge in medicinal chemistry with focus on oligo/nucleotides for 8+ years with a track record of deliverables. Experience in solid phase oligonucleotide synthesis is considered a plus A track record of people leadership and development skills A mind-set of curiosity and openness to diverse thinking, with an enthusiasm to develop yourself and others Innovative and independent problem-solving skills Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery Aptitude to work in a fast-paced team-oriented matrix environment Excellent written and verbal communication and strong influencing skills, with an ability to present and discuss project strategies and challenges Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10043483 May 13, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated and curious lab-based Senior Scientist I whose focus will be on siRNA discovery in the xRNA Team within Biomedical Research in Basel. The team develops next-generation xRNA therapeutics in a collaborative and innovation driven environment, aiming to transform the lives of millions of patients with unmet medical needs. The successful candidate will have a background in biology research with ideally a focus in RNA biology. The ideal candidate will have strong experience in medium - to high throughput screening using automation, cell culture techniques, assay development and technologies such as liquid handlers. About the Role Key Responsibilities: Design, plan and conduct routine siRNA screening in cell-based transfection assays using qPCR and reporter-based systems Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation Contribute to designing, and developing automated workflows Operate automated liquid handling robotics platform Work collaboratively in a matrix-oriented environment and present work on a regular basis in unit meetings Acting as a point-of-contact in the team of day to day activities Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner Role Requirements: A higher degree in biology (such as Bachelor-s or Master-s), or Apprenticeship with equivalent industry experience in biochemistry, cell biology or related scientific discipline A minimum of 5 years of research experience gained ideally in a lab environment in a pharma and/or biotech industry setting Expertise in cell culture and conducting expression read outs (e.g. qPCR, Western Blot, ELISA) Experience with liquid handlers and automation of cell based assays Strong competence in MS office applications, expertise in Excel and maintenance of electronic Lab Notebooks Strong multi-tasking, organizational, attention to detail, verbal/written communication skills Ability to collaborate and thrive in fast-paced, team-oriented environment Desired Requirements: Primary cell culture experience Expertise in Spotfire and/or GraphPad PRISM Expertise with BioMek or Opentrons liquid handlers *Restrictions on flexible working may apply and are discretionary and can be discussed at interview, if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland; Responsible for timely, independent management of complex intellectual property (IP) administrative, filing and legal support tasks. Proactive involvement in a high performing team providing a diverse range of complex IP administrative support for a defined group of patent practitioners in regional, international and foreign filing. Maintain and manage a complex, accurate docket, using a patent docketing system. Provides expert knowledge and understanding of IP law and practice issues. Undertakes operational and strategic responsibilities to maximize the effectiveness of paralegal sup-port at a local and global level. Responsible for applying, maintaining and contributing to the improvement of the department best practices. Responsible for training others in all areas of European Patents (EP) and foreign patent matters. Lead teams within the Patent Support team in areas of efficiency and improvement of current processes About the Role Your responsibilities include, but not limited to : Filing of EP/international and foreign patent applications and related correspondence from filing to issuance of grant. Responsible for EP and international patent filings, patent nationalizations into foreign jurisdictions, as well as foreign filings under other conventions. Responsible for preparing all documents required in connection with EP, Patent Cooperation Treaty (PCT) and foreign applications; proactively initiates preparation of responses to official communications and notifications. Maintain and share advanced knowledge of latest patent rules and adapting practices to comply. Monitor and updating electronic docket(s) for responsible attorney(s) and assigned paralegal tasks on a daily basis. Monitor all assigned cases and proactively ensuring that all related deadlines are met in a timely manner. Independent, proactive and critical review, maintenance and assistance of responsible attorney(s)’ dockets and workload. Coordinate outsourcing, transfer in and transfer out of patent files and responsibilities in a timely and efficient manner, minimizing risk of loss of rights. Communicate effectively with colleagues, inventors, foreign agents and other associates. Actively participate in patent group and cross-divisional meetings as needed. Role includes on an as needed basis the flexibility to provide support in other areas within the Patent Support team (i.e. annuities, invoicing and data input). Undertake projects to address global prosecution and operational issues affecting department. Leads teams in development of procedures and processes. Ability to conduct meetings as needed. Recommends areas/systems of possible improvement in efficiencies in procedures. What you'll bring to the role: Relevant degree, Law - Paralegal/equivalent IP certification or equivalent experience Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as a patent paralegal in a patent law firm or corporation with international and foreign filing experience. Ability to deal with a highly complex environment - manages workload and work product with high quality. Advanced knowledge and competency of patent database and report generating tools. Ability to work well and meet deadlines, without supervision, in an electronic office environment. Well-developed research and critical thinking skills, and sound decision-making abilities, with attention to detail to produce consistently accurate work Excellent analytical skills, organizational, and communication skills. Liaise with other cross-divisional groups to prevent duplication of effort and to ensure that effective knowledge sharing occurs. Demonstrates leadership qualities and ability to mentor and develop the technical competence of other paralegals. Ability to act as a champion for the Patent Support team at a NIBR site. Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Operations Program Head (COPH) is accountable to deliver data-driven, actionable operational and strategic insights for execution of a clinical development program and all associated trials by representing GCO at the Global Clinical Team (GCT) as well as at the Global Program Team (GPT). The COPH is accountable to plan the strategic operationalization of clinical drug development programs and trials in line with the needs of the EPTs/GPTs. This specific COPH role may be focused within Neuroscience programs. About the Role Major accountabilities: Lead operational delivery of the clinical development program and is responsible for the overall operational execution of the clinical program and related trials, as aligned with the IDP/CDP. Single GCO point of contact for assigned clinical development program and related trials. Key partner to GPCH during strategy, planning and execution stage of the program and related trials ensuring that the clinical science and strategy are consistently harmonized with an operationally feasible approach within the OEP-defined operational boundaries, so that the trials generate reliable information to answer the research questions and support decision making while protecting study participants. Leads operational delivery of the assigned program and related clinical trials and for all related strategic planning, prioritization of activities within that program and owns the early viability and feasibility assessment done by the GCO sub-teams as well as the development of operational scenarios for the execution of assigned programs and trials. Oversight and management of clinical trial budget for the assigned program and trials per OEP aligned with financial toll gates (e.g. IMB) and oversight of scope changes throughout the trial and program duration. Acts as a key partner to the GCO DU Head to use the operational insights developed with the GCO sub-team to actively shape the GDD DU strategy by driving the science of operations and GCO’s voice to ensure that the development strategy is operationally executable, thus contributing to both GCO and GDD DU mid to long term success. Is a key contact to senior leaders in GCO and beyond. Empowered to manage stakeholders, resolve conflict, and facilitate agreement. Actively monitor evolution and trends in Biopharmaceutical industry and may represent GCO and Novartis at Industry consortia. May be a member of Early Program Teams, providing an early and proactive assessment of operational viability of new clinical programs and ensuring that GCO’s assessment is correctly reflected in the overall program plans. In partnership with the GCO DU Head ensure that novel programs are reflected in the mid-long term GCO strategy and that GCO is prepared for their operationalization. The COPH champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. Essential Requirements : Bachelors in life science/healthcare required; Advanced degree or equivalent education/degree in life sciences/ healthcare preferred (PhD/MD/ PharmD/ Masters) and 10+ years relevant experience in pharmaceutical drug development. Experience in managing associates globally and in management in a matrix organization. Proven ability to lead cross functional matrix teams applying product-oriented agile ways of working. Strong leadership, interpersonal and problem-solving skills. High resilience and ability to advocate and implement new ways of working. Extensive knowledge of clinical development processes, preferably extensive knowledge of Novartis late-stage development processes or high likelihood to develop it within 6 months after appointment. Proven ability to lead in times of organizational transformation and to lead across organizational boundaries. Strong knowledge of therapeutic area or high likelihood to develop it within 6 months after appointment. Strong matrix management skills for bridging stakeholders (business, scientific, technical) Strong relationship-building skills; can influence, negotiate with and motivate executive leadership Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help develop therapeutic approaches to restore mitochondrial function. The project will focus on the targeted degradation of dysfunctional mitochondria in diseases of aging with a focus on neurodegeneration. You will be part of our Diseases of Aging and Regenerative Medicine (DARe) and Discovery Science (DSc) teams in Basel, Switzerland, driving research towards the identification of surface markers of damaged/dysfunctional mitochondria using proteomics approaches. You will drive experiments to selectively degrade dysfunctional mitochondria and evaluate the impact on cellular health in cell models of diseases of aging. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st, 2025 Location: Campus Basel, Switzerland About the Role Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Conduct research towards identification of surface markers of damaged/dysfunctional mitochondria using proteomics approaches. Drive experiments to selectively degrade dysfunctional mitochondria. Evaluate the impact of selective degradation of dysfunctional mitochondria on cellular health in cell models of diseases of aging. Be part of cross-functional teams, including experts in autophagy, mitochondrial biology, proteomics, and disease biology. Present research findings at internal and external meetings and contribute to high-impact publications. Role Requirements : PhD in a relevant field such as molecular biology, biochemistry, chemical biology, cell biology or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Experience in autophagy research, mitochondrial biology, protein degradation and/or surface proteomics methodologies will be considered a plus Strong skills in data analysis; proficiency in programming languages such as R or Python is a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by July 1st, 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053521 Jun 04, 2025 Switzerland Summary About the role We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help develop therapeutic approaches to restore mitochondrial function. The project will focus on the targeted degradation of dysfunctional mitochondria in diseases of aging with a focus on neurodegeneration. You will be part of our Diseases of Aging and Regenerative Medicine (DARe) and Discovery Science (DSc) teams in Basel, Switzerland, driving research towards the identification of surface markers of damaged/dysfunctional mitochondria using proteomics approaches. You will drive experiments to selectively degrade dysfunctional mitochondria and evaluate the impact on cellular health in cell models of diseases of aging. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st, 2025 Location: Campus Basel, Switzerland About the Role Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Conduct research towards identification of surface markers of damaged/dysfunctional mitochondria using proteomics approaches. Drive experiments to selectively degrade dysfunctional mitochondria. Evaluate the impact of selective degradation of dysfunctional mitochondria on cellular health in cell models of diseases of aging. Be part of cross-functional teams, including experts in autophagy, mitochondrial biology, proteomics, and disease biology. Present research findings at internal and external meetings and contribute to high-impact publications. Role Requirements : PhD in a relevant field such as molecular biology, biochemistry, chemical biology, cell biology or a related field. Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Experience in autophagy research, mitochondrial biology, protein degradation and/or surface proteomics methodologies will be considered a plus Strong skills in data analysis; proficiency in programming languages such as R or Python is a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity How to apply Please submit your CV and cover letter by July 1st, 2025 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Biologics Research Center (BRC) at Biomedical Research is seeking a highly skilled Structural Bioinformatician / computational chemist specializing in protein structure predictions, protein-protein/ ligand interactions, molecular dynamics simulations, and protein/ DNA /RNA structure analysis. The ideal candidate will join our Bioinformatics and Biotherapeutics Modelling team and contribute to our innovative biologics projects. About the Role Your responsibilities will include: Actively contribute to the biologics discovery pipeline and innovation-related programs by applying structure modeling methods to design novel molecules, optimize lead candidates, and design reagents at different stages of the drug discovery process. Assist scientists across the organization in the analysis and design of biologics sequences and structures, including xRNA therapeutic, advancing projects from early discovery to optimization stages. Apply, develop, and improve computational structural modelling methods to analyze data and design functional properties of drug candidates. Collect, analyze, and integrate diverse types of data, including structural data from different projects, to build predictive models, formulate hypotheses, and generate actionable knowledge. Contribute to the design, utilization, and improvement of bioinformatics tools in the field of molecular modelling to analyze sequence and structure data for knowledge generation. Work closely with experimental scientists, fostering a collaborative and multidisciplinary environment to drive project success. What you will bring to the role To be successful in this role, the ideal candidate should possess the following qualifications and skills: Educational Background: Recent Ph.D. (graduated within the last 3-6 months), MS (with 4+ years of relevant industry research experience) or equivalent degree degree in theoretical/ Computational chemistry, bioinformatics, structural biology, or a related field. Preferable experience includes structure-based drug design, QM/MM calculations, MD simulations (with enhanced sampling), molecular modeling, molecular design, and AI. Experience: Prior experience in the pharmaceutical or biotechnology industry is advantageous but not essential. Experience in a research or academic setting with a focus on biologics , including RNA or antibody based therapeutics, is also valuable. Technical Expertise: Proficiency in computational structural biology, molecular modeling, molecular dynamics simulations, and structural bioinformatics tools and software (MOE, Schrodinger, Rosetta, or similar) for structural analysis and structure-based biologics design. A comprehensive understanding of RNA structural biology and RNA-ligand interactions is preferred. AI/ML Proficiency: Experience in incorporating AI/ML models into in silico workflows, as well as monitoring performance, retraining, and updating models, is advantageous. Analytical Skills: Strong ability to analyze and interpret complex biological data, particularly in the context of protein sequences and structures. Programming Skills: Competence in programming languages such as Python, R, or similar, and experience with bioinformatics databases and tools. Familiarity with version control systems like Git for collaborative coding and project management is a plus. Innovation: A creative and innovative mindset, with a keen interest in advancing the field of biologics through cutting-edge computational methods. Problem-Solving: Demonstrated ability to develop hypotheses, design experiments, and drive projects to successful completion. Collaborative Spirit: Excellent communication and teamwork skills, with the ability to work effectively in a multidisciplinary environment. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050376 May 20, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Biologics Research Center (BRC) at Biomedical Research is seeking a highly skilled Structural Bioinformatician / computational chemist specializing in protein structure predictions, protein-protein/ ligand interactions, molecular dynamics simulations, and protein/ DNA /RNA structure analysis. The ideal candidate will join our Bioinformatics and Biotherapeutics Modelling team and contribute to our innovative biologics projects. About the Role Your responsibilities will include: Actively contribute to the biologics discovery pipeline and innovation-related programs by applying structure modeling methods to design novel molecules, optimize lead candidates, and design reagents at different stages of the drug discovery process. Assist scientists across the organization in the analysis and design of biologics sequences and structures, including xRNA therapeutic, advancing projects from early discovery to optimization stages. Apply, develop, and improve computational structural modelling methods to analyze data and design functional properties of drug candidates. Collect, analyze, and integrate diverse types of data, including structural data from different projects, to build predictive models, formulate hypotheses, and generate actionable knowledge. Contribute to the design, utilization, and improvement of bioinformatics tools in the field of molecular modelling to analyze sequence and structure data for knowledge generation. Work closely with experimental scientists, fostering a collaborative and multidisciplinary environment to drive project success. What you will bring to the role To be successful in this role, the ideal candidate should possess the following qualifications and skills: Educational Background: Recent Ph.D. (graduated within the last 3-6 months), MS (with 4+ years of relevant industry research experience) or equivalent degree degree in theoretical/ Computational chemistry, bioinformatics, structural biology, or a related field. Preferable experience includes structure-based drug design, QM/MM calculations, MD simulations (with enhanced sampling), molecular modeling, molecular design, and AI. Experience: Prior experience in the pharmaceutical or biotechnology industry is advantageous but not essential. Experience in a research or academic setting with a focus on biologics , including RNA or antibody based therapeutics, is also valuable. Technical Expertise: Proficiency in computational structural biology, molecular modeling, molecular dynamics simulations, and structural bioinformatics tools and software (MOE, Schrodinger, Rosetta, or similar) for structural analysis and structure-based biologics design. A comprehensive understanding of RNA structural biology and RNA-ligand interactions is preferred. AI/ML Proficiency: Experience in incorporating AI/ML models into in silico workflows, as well as monitoring performance, retraining, and updating models, is advantageous. Analytical Skills: Strong ability to analyze and interpret complex biological data, particularly in the context of protein sequences and structures. Programming Skills: Competence in programming languages such as Python, R, or similar, and experience with bioinformatics databases and tools. Familiarity with version control systems like Git for collaborative coding and project management is a plus. Innovation: A creative and innovative mindset, with a keen interest in advancing the field of biologics through cutting-edge computational methods. Problem-Solving: Demonstrated ability to develop hypotheses, design experiments, and drive projects to successful completion. Collaborative Spirit: Excellent communication and teamwork skills, with the ability to work effectively in a multidisciplinary environment. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Data and Digital Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary This is a unique opportunity for a BSc/MSc student intern to work in a highly interdisciplinary environment at the intersection of pharmaceutical sciences, process modeling and data science. In this role, you will be part of the digital transformation, driving model-driven decision-making and optimizing the drug development process. This experience will allow you to apply your academic knowledge in a practical setting, collaborate with experts from various fields, and contribute to innovative solutions in pharmaceutical manufacturing. Start: as soon as possible End: 30. November 2025 Location: Campus Basel About the Role Your responsibilities: Integrate the theoretical Capped Drucker-Prager model into a real-world industrial setting at Novartis. Adapt the model using FEM tools (e.g. Comsol Multiphysics) to simulate the physical phenomena occurring during the tablet compaction process, including the analysis of mechanical stresses and thermal effects. Calibrate the model parameters to match empirical data from the production environment. Evaluate if the model accurately reflects the behavior of the compaction machinery and the properties of the tablets. Prepare and present research findings in a final presentation and report. Minimum requirements: BSc/MSc degree in Pharmaceutical Sciences, Chemical/Mechanical/Process engineering, Material Sicences or similar. Knowledge of Capped Drucker-Prager model. Good communication skills (English) and data visualization skills. Flexible and open minded. Ability to work independently and in collaboration with multiple teams, ability to work in multidisciplinary teams and multicultural environment. Of advantage: Experience with Comsol Multiphyisics software. Experience in data science applied to scientific problems. Experience in programing languages like Python. Please note that we can only accept applicants who are eligible to work in Switzerland . Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Diese Position ist eine leitende Funktion, die für das Management und die Überwachung der Tierhaltungseinrichtungen verantwortlich ist. Dazu gehört die operative Unterstützung der in den Tierhaltungen tätigen Personen sowie die Betreuung und Weiterentwicklung der Anlagen, Geräte und Ausstattung in einem multidisziplinären biomedizinischen Forschungsumfeld, dass sich über mehrere Gebäude erstreckt und mit verschiedenen Spezies arbeitet. Diese Rolle erfordert ausgeprägte Führungskompetenzen in interdisziplinären Teams und Matrixstrukturen, die Fähigkeit, mit verschiedenen Forschungsbereichen zu arbeiten, ausgezeichnete Kommunikations- und Organisationsfähigkeiten sowie ein starkes Engagement für den Tierschutz und die Bereitschaft, sich selbst und andere weiterzuentwickeln. About the Role Hauptaufgaben: Campusplanung: Sanierung und Optimierung der Tierhaltungsanlagen. Schnittstellenmanagement: Zwischen Novartis und Dienstleistern (ISS, CBRE, FMI, IOB). Überwachung und Optimierung der Käfigreinigung: Planung und Koordination von Schnittstellen, Abläufen, Anpassungs- und Optimierungsprojekten. Business Continuity: Anleitung und Überwachung des Facility Managements (CBRE) zur ständigen Sicherstellung der Medienversorgung und Umgebungsparameter in der Tierhaltung. Planung und Koordination der Umnutzung von in vivo Bereichen. Beratungsleistungen: Beratung zur Weiterentwicklung der Vivarium Operations Prozesse. Koordination von Reparaturen, Service und Wartung: Für tierhaltungsspezifische Anlagen und Geräte (z.B. IVC-Gebläse/Racks, Käfigwechselstationen) und die Gebäudeinfrastruktur. Evaluierung, Beschaffung und Lagerverwaltung von Material und Geräten für den Tierhaltungsbetrieb und die Versorgung der Versuchstiere. Ansprechpartner: Für CM und Forschungspartner (BR Labore), Unterstützung bei logistischen Angelegenheiten und Erarbeitung/Bereitstellung von Lösungen. Budgetangelegenheiten: Beitrag zu Tierhaltungs-Budgetfragen (z.B. Budgeterstellung, Bestellungen, Lieferungen). SOPs: Beitrag zur Erstellung und periodischen Überprüfung von CM-Betriebs-SOPs. Validierung neuer Technologien: Innerhalb der Tierhaltung. Mitglied von NEM-Basel und CM-Pikett Gruppe. Vertretungen und Personalmanagement: Head Vivarium Operations und VO-Supervisor für das Tierpflegepersonal (Verantwortung für die Führung und Entwicklung des tierpflegerischen Personals). Leistungsindikatoren: Kooperation mit dem Head VO zur Sicherstellung der Funktionstüchtigkeit aller tierhaltungsspezifischer Anlagen und Geräte, zur Gewähleistung einer «state-of-the-art» Arbeitsumgebung und zur optimalen Unterstützung des VO-Personals bei dessen verantwortungsvoller Versorgung und Pflege der Tiere gemäss höchsten tierschützerischen Massstäben. Beherrschung aller erforderlichen betrieblichen Fähigkeiten. Teamorientierung und Fähigkeit zu interaktivem Arbeiten. Fokussierung auf effiziente und konsistente Erledigung von Aufgaben. Einhaltung aller internen und externen Vorschriften gemäss dem «Guide for the Care and Use of Laboratory Animals». Kontinuierliche Weiterbildung und Wahrnehmung beruflicher Entwicklungsmöglichkeiten zur Verbesserung und Erweiterung relevanter persönlicher Fähigkeiten und Kenntnisse. Zusammenarbeit mit in vivo Forschenden zur Erreichung wissenschaftlicher Ziele. Identifizierung von Prozessineffizienzen vor Ort, Optimierung von Prozessen und proaktive Entwicklung von Lösungen für betriebliche Herausforderungen sowie Optimierungen von Gebäuden und Infrastruktur. Beitrag zur Schulung neuer VO-Mitarbeitender nach Bedarf. Effektive Führung von Mitarbeitenden im Vertretungsfall. Anforderungen: Bildung: Bachelorabschluss in einer Naturwissenschaften oder eine gleichwertige Kombination aus Erfahrung und höherer Bildung erforderlich. Erfahrung: Nachgewiesene mehrjährige Erfahrung in einem Labortierprogramm erforderlich. Erfahrung in der Personalführung und/oder Teamleitung von Vorteil. Sprachen: Deutsch und Englisch erforderlich. Fähigkeiten und Kenntnisse: Fähigkeit zu sicherer und eloquenter Kommunikation über betriebliche Themen in der Abteilung und mit der Forschungsgemeinschaft sowie Schaffung einer zwischenmenschlich-konstruktiven und kollegialen Arbeitsatmosphäre. Starker Sinn für persönliche Verantwortung, Zuverlässigkeit und Integrität. Fähigkeit zur Identifizierung und Lösung von mitunter komplexen betrieblichen Herausforderungen in der Tierhaltung. Selbständiges und eigenverantwortliches Arbeiten bei gleichzeitiger Motivation des ganzen Teams. Fähigkeit zur Koordination von Übergangslösungen und Zeitplanänderungen. Sehr gute Kenntnisse in der Tierpflege und starke Verpflichtung zum Tierschutz. Engagement für die berufliche Entwicklung des Teams und kontinuierliches Lernen. Zusätzliche Anforderungen: Fähigkeit, 20 kg zu heben, schwere Gegenstände zu bewegen, längere Zeit im Stehen zu arbeiten und repetitive Bewegungsaufgaben auszuführen. Bereitschaft zur Unterstützung an Wochenenden, Feiertagen und als Pikettdienst. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051898 Jun 04, 2025 Switzerland Summary Diese Position ist eine leitende Funktion, die für das Management und die Überwachung der Tierhaltungseinrichtungen verantwortlich ist. Dazu gehört die operative Unterstützung der in den Tierhaltungen tätigen Personen sowie die Betreuung und Weiterentwicklung der Anlagen, Geräte und Ausstattung in einem multidisziplinären biomedizinischen Forschungsumfeld, dass sich über mehrere Gebäude erstreckt und mit verschiedenen Spezies arbeitet. Diese Rolle erfordert ausgeprägte Führungskompetenzen in interdisziplinären Teams und Matrixstrukturen, die Fähigkeit, mit verschiedenen Forschungsbereichen zu arbeiten, ausgezeichnete Kommunikations- und Organisationsfähigkeiten sowie ein starkes Engagement für den Tierschutz und die Bereitschaft, sich selbst und andere weiterzuentwickeln. About the Role Hauptaufgaben: Campusplanung: Sanierung und Optimierung der Tierhaltungsanlagen. Schnittstellenmanagement: Zwischen Novartis und Dienstleistern (ISS, CBRE, FMI, IOB). Überwachung und Optimierung der Käfigreinigung: Planung und Koordination von Schnittstellen, Abläufen, Anpassungs- und Optimierungsprojekten. Business Continuity: Anleitung und Überwachung des Facility Managements (CBRE) zur ständigen Sicherstellung der Medienversorgung und Umgebungsparameter in der Tierhaltung. Planung und Koordination der Umnutzung von in vivo Bereichen. Beratungsleistungen: Beratung zur Weiterentwicklung der Vivarium Operations Prozesse. Koordination von Reparaturen, Service und Wartung: Für tierhaltungsspezifische Anlagen und Geräte (z.B. IVC-Gebläse/Racks, Käfigwechselstationen) und die Gebäudeinfrastruktur. Evaluierung, Beschaffung und Lagerverwaltung von Material und Geräten für den Tierhaltungsbetrieb und die Versorgung der Versuchstiere. Ansprechpartner: Für CM und Forschungspartner (BR Labore), Unterstützung bei logistischen Angelegenheiten und Erarbeitung/Bereitstellung von Lösungen. Budgetangelegenheiten: Beitrag zu Tierhaltungs-Budgetfragen (z.B. Budgeterstellung, Bestellungen, Lieferungen). SOPs: Beitrag zur Erstellung und periodischen Überprüfung von CM-Betriebs-SOPs. Validierung neuer Technologien: Innerhalb der Tierhaltung. Mitglied von NEM-Basel und CM-Pikett Gruppe. Vertretungen und Personalmanagement: Head Vivarium Operations und VO-Supervisor für das Tierpflegepersonal (Verantwortung für die Führung und Entwicklung des tierpflegerischen Personals). Leistungsindikatoren: Kooperation mit dem Head VO zur Sicherstellung der Funktionstüchtigkeit aller tierhaltungsspezifischer Anlagen und Geräte, zur Gewähleistung einer «state-of-the-art» Arbeitsumgebung und zur optimalen Unterstützung des VO-Personals bei dessen verantwortungsvoller Versorgung und Pflege der Tiere gemäss höchsten tierschützerischen Massstäben. Beherrschung aller erforderlichen betrieblichen Fähigkeiten. Teamorientierung und Fähigkeit zu interaktivem Arbeiten. Fokussierung auf effiziente und konsistente Erledigung von Aufgaben. Einhaltung aller internen und externen Vorschriften gemäss dem «Guide for the Care and Use of Laboratory Animals». Kontinuierliche Weiterbildung und Wahrnehmung beruflicher Entwicklungsmöglichkeiten zur Verbesserung und Erweiterung relevanter persönlicher Fähigkeiten und Kenntnisse. Zusammenarbeit mit in vivo Forschenden zur Erreichung wissenschaftlicher Ziele. Identifizierung von Prozessineffizienzen vor Ort, Optimierung von Prozessen und proaktive Entwicklung von Lösungen für betriebliche Herausforderungen sowie Optimierungen von Gebäuden und Infrastruktur. Beitrag zur Schulung neuer VO-Mitarbeitender nach Bedarf. Effektive Führung von Mitarbeitenden im Vertretungsfall. Anforderungen: Bildung: Bachelorabschluss in einer Naturwissenschaften oder eine gleichwertige Kombination aus Erfahrung und höherer Bildung erforderlich. Erfahrung: Nachgewiesene mehrjährige Erfahrung in einem Labortierprogramm erforderlich. Erfahrung in der Personalführung und/oder Teamleitung von Vorteil. Sprachen: Deutsch und Englisch erforderlich. Fähigkeiten und Kenntnisse: Fähigkeit zu sicherer und eloquenter Kommunikation über betriebliche Themen in der Abteilung und mit der Forschungsgemeinschaft sowie Schaffung einer zwischenmenschlich-konstruktiven und kollegialen Arbeitsatmosphäre. Starker Sinn für persönliche Verantwortung, Zuverlässigkeit und Integrität. Fähigkeit zur Identifizierung und Lösung von mitunter komplexen betrieblichen Herausforderungen in der Tierhaltung. Selbständiges und eigenverantwortliches Arbeiten bei gleichzeitiger Motivation des ganzen Teams. Fähigkeit zur Koordination von Übergangslösungen und Zeitplanänderungen. Sehr gute Kenntnisse in der Tierpflege und starke Verpflichtung zum Tierschutz. Engagement für die berufliche Entwicklung des Teams und kontinuierliches Lernen. Zusätzliche Anforderungen: Fähigkeit, 20 kg zu heben, schwere Gegenstände zu bewegen, längere Zeit im Stehen zu arbeiten und repetitive Bewegungsaufgaben auszuführen. Bereitschaft zur Unterstützung an Wochenenden, Feiertagen und als Pikettdienst. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No

Summary We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. About the Role We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. This legal trainee position offers excellent opportunities to gain first-class, hands-on in-house legal experience within the stimulating, multinational environment of a leading pharmaceutical company. Duration: 6 months Start: January 1, 2025 Your responsibilities will include: • Support a diverse range of commercial matters relating to direct and indirect procurement, manufacturing, IT • Support diverse range of legal projects, e.g. contract templates, legal trainings, global legal research projects, digitalization, outsourcing, etc. • Assist with the drafting, negotiation and review of a variety of transactional, commercial and agreements • Draft legal memoranda on a wide variety of legal issues and disputes, Draft document and key position summaries • Provide legal advice to internal clients • You will be supervised and guided by a range of lawyers on different levels of the company, ensuring a great learning experience What you’ll bring to the role: Essential: • Swiss Law degree (Master of Law and Bachelor of Law has to be on Swiss Law), master's degree needs to be completed before start date • Business-level English skills (written and spoken), additional language is a plus • Interest in legal topics in a large multinational group of companies • High motivation to perform, to discover and learn new things and ability to work independently Desirable requirements: • Prior legal professional experience in a law firm, court or legal in-house department (internships etc.) would be helpful. We are also open to applicants without prior experience who have a strong interest and are motivated to learn on the job • Other professional experience in the corporate environment is a plus Please submit a cover letter that includes your motivation for the position and from when you will be available. Thank you. Why Novartis Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data Strategy and Management Platform, the Business Architecture & Data Integrations Capability Lead owns and oversees all aspects the Capability and contributes to the overall Platform strategy delivering business benefits, harmonization and continuous improvements. The Business Architecture & Data Integrations Capability lead is accountable for the overall cataloging of business data, defining data model requirements and Data Integration requirements. This role requires a deep understanding of regulatory data and how it flows through systems across the regulatory landscape, e.g. Data Lakes, Enterprise Data Warehouses, 3rd-party data integrations, regulatory technology solutions, etc. and how data flows in the registrations ecosystem across the Novartis Enterprise. About the Role Major accountabilities: Lead a team to ensure alignment with organizational goals and business priorities related to Business Architecture and Data Integrations Support the strategic vision for the Data Strategy and Management Platform, from a Capability level Define, prioritize, and deploy an integrated Capability roadmap working in close collaboration with relevant stakeholders and DDIT partners, ensuring alignment with the Data Strategy and Management Platform, Development and Enterprise data and technology strategy roadmaps Represent the Capability in digital governance boards and leadership meetings across the organization Represent the Capability in digital networks, externally (e.g. across Industries) as needed Oversee integrations with Products underlying the Capability Build and maintain collaborative and productive partnerships within the Capability and the Platform, and with relevant stakeholders to achieve business priorities. Oversees the cataloging and technical controls of the RA Data model in line with Novartis strategy and Industry Standards, business data architecture, Logical data model, Integration requirements, data model requirements and approves and secures data governance policies and processes Minimum Requirements: Bachelor’s degree, master’s; Advanced degree in life science, pharmaceutical, technology or data science preferred. 8+ years of relevant industry experience Strong understanding and direct relevant experience with the Business Architecture and Data Integrations landscape of pharmaceutical regulatory affairs and Regulatory Information Management Practical experience in technology process requirements and business administration management Deep knowledge of regulatory standards and structured data submissions Strong network and exposure to the external environment and ability to represent company and influence in Trade organizations (e.g., EFPIA, PhRMA), International Organizations (ISO), and collaboration with regulators (e.g. ICH, EMA SPOR), or consortiums Strong strategic problem-solving skills and ability to navigate un-charted territory without clear precedent Experience presenting/speaking at a senior management level with a proven track record of effectively communicating complex initiatives Demonstrated leadership in driving risk assessment and mitigation, clear strategic thinking, prioritization, maintaining awareness of business impact Excellent verbal and written communications Strong negotiation skills Broad experience in quality assurance/compliance, computer system validation within the pharmaceutical/biotech arena, the management and conduct of audits, stakeholder focus, and strong knowledge of regulatory requirements Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data Strategy and Management Platform team, the Data Governance and Quality Capability Lead is responsible for independently driving and implementing data standards and strategies for emerging data-driven HA requirements, and relevant systems’ governance processes across all domains and functions, in support of the NVS global product portfolios to improve data maturity according to RA business objectives. The Data Governance and Quality Capability Lead is accountable to drive harmonization and continuous improvement of Data Governance related activities and initiatives in close alignment with internal and external stakeholders to improve data maturity according to RA business objectives. The Capability Lead will drive the Centralized Data Quality Management culture in Regulatory Affairs and ensure Data Quality consistency, correctness and completeness across all applicable RA systems and platforms. About the Role Major accountabilities: Lead a team to ensure alignment with organizational goals and business priorities related to Data Governance and Quality Serve as Data Governance and Quality Capability Lead for RA and as the point of contact for GDD Data team Lead RA cross-functional teams to develop data roadmap, in alignment with cross-domain Data Governance boards Accountable to create and implement data management and quality strategy Expert contributor to influence draft guidance on data standards / specifications / implementation from Health Authorities and Trade Organizations. Prepare interpretative analyses about impact on internal data and digital processes. Collaborate with Development Data Management and DDIT partners to develop and implement RA Data Governance structures (boards) and policies, ensuring involvement of Business Process Owners (BPOs) and business SMEs. Oversee vendors at the Capability level, in collaboration with IT and the External Partnerships Teams Manage Data Governance and metrics reporting on data operating model throughout the DQM lifecycle Responsible for configuration, decision making and outcome, impacting the capability, with involvement of relevant Business Process Owner(s), business SMEs and stakeholders Minimum Requirements: Bachelor’s degree, master’s; Advanced degree in life science, pharmaceutical, technology or data science preferred 8+ years of relevant industry experience Strong understanding and direct relevant experience with the Data Strategy and Management landscape of pharmaceutical regulatory affairs and Regulatory Information Management Strong network and exposure to the external environment and ability to represent company and influence in Trade organizations (e.g., EFPIA, PhRMA), International Organizations (ISO), and collaboration with regulators (e.g. ICH, EMA SPOR), or consortiums Advanced knowledge of worldwide evolving external data standards as well as drug registration and approval processes and related document format requirements and in-depth knowledge of good Regulatory compliance and intelligence practices, policies, procedures Strong understanding of regulatory requirements and structured data submissions standards and initiatives Excellent business writing, communication and effective presentation skills. Extensive experience leading meetings, driving change and cross-functional teams Strong strategic problem-solving skills and ability to innovate, analyze and navigate un-charted territory without clear precedent, ability to troubleshoot effectively, accurately and independently. Strong negotiation skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Drug Discovery Biology group within the Discovery Sciences department in Basel, Switzerland, is seeking a highly motivated Research Scientist to join our interdisciplinary team. Our group supports early drug discovery projects across disease indications. We are a highly collaborative and global group exploring the interface of chemistry and biology for the discovery of small molecule therapeutics. You will work in a laboratory applying state-of-the-art technologies to develop biochemical and cellular assays and run compound screens for hit identification and to support hit-to-lead-generation. You will have opportunities to work on a variety of projects and acquire new skills. Please note there is no relocation support for this role. About the Role Your responsibilities include, but are not limited to: Use a variety of technologies to develop and miniaturize biochemical and cellular assays. Independently design, execute, and analyze experiments and screens for drug discovery projects. Contribute experimentally and intellectually to early drug discovery projects by working in multidisciplinary and collaborative teams. Prepare presentations and communicate results in internal meetings. Assist in method development and validation of new methodologies and instrumentation as needed. Ensure high quality of experimental data and rigorous and timely documentation in the electronic Lab notebook. Contribute to the maintenance of the lab and the lab equipment. Minimum requirements: Apprenticeship, bachelor's or master's degree in biology, chemistry or related disciplines. Relevant experience working in a laboratory in industry or academia. Proficient in a variety of relevant laboratory methods and technologies in biochemistry, molecular biology, or cell biology. Scientific curiosity, initiative and good organizational skills. Interest in working in open and collaborative teams. Excellent interpersonal skills. Excellent communication and presentation skills in oral and written English. Desirable: Experience with relevant assays, such as cellular assays, competitive binding and enzyme activity assays; as well as readout technologies, such as cell imaging, fluorescence and luminescence. Familiar with assay miniaturization and screening. Strong skills handling large data sets and performing data analysis. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051870 May 22, 2025 Switzerland Summary The Drug Discovery Biology group within the Discovery Sciences department in Basel, Switzerland, is seeking a highly motivated Research Scientist to join our interdisciplinary team. Our group supports early drug discovery projects across disease indications. We are a highly collaborative and global group exploring the interface of chemistry and biology for the discovery of small molecule therapeutics. You will work in a laboratory applying state-of-the-art technologies to develop biochemical and cellular assays and run compound screens for hit identification and to support hit-to-lead-generation. You will have opportunities to work on a variety of projects and acquire new skills. Please note there is no relocation support for this role. About the Role Your responsibilities include, but are not limited to: Use a variety of technologies to develop and miniaturize biochemical and cellular assays. Independently design, execute, and analyze experiments and screens for drug discovery projects. Contribute experimentally and intellectually to early drug discovery projects by working in multidisciplinary and collaborative teams. Prepare presentations and communicate results in internal meetings. Assist in method development and validation of new methodologies and instrumentation as needed. Ensure high quality of experimental data and rigorous and timely documentation in the electronic Lab notebook. Contribute to the maintenance of the lab and the lab equipment. Minimum requirements: Apprenticeship, bachelor's or master's degree in biology, chemistry or related disciplines. Relevant experience working in a laboratory in industry or academia. Proficient in a variety of relevant laboratory methods and technologies in biochemistry, molecular biology, or cell biology. Scientific curiosity, initiative and good organizational skills. Interest in working in open and collaborative teams. Excellent interpersonal skills. Excellent communication and presentation skills in oral and written English. Desirable: Experience with relevant assays, such as cellular assays, competitive binding and enzyme activity assays; as well as readout technologies, such as cell imaging, fluorescence and luminescence. Familiar with assay miniaturization and screening. Strong skills handling large data sets and performing data analysis. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you a highly skilled and ambitious medical professional with a passion for research? If so, we have an exceptional opportunity for you! Novartis, a world-class pharmaceutical company, is seeking a Clinical Development Medical Director - Renal to join our team in Switzerland. As a Research role, this position offers a unique chance to contribute to groundbreaking medical advancements in the field of renal medicine. About the Role Novartis is seeking a highly qualified Clinical Development Medical Director - Renal **80-100% to join our exceptional team in Switzerland or the UK. As a world-class pharmaceutical company, Novartis is dedicated to improving global health through groundbreaking research and innovative solutions. Responsibilities: Lead the clinical development activities for renal disease therapeutic area, ensuring flawless execution of clinical trials. Collaborate with cross-functional teams to design and implement clinical development plans. Provide medical expertise and guidance throughout the clinical development process. Successfully compete clinical trial protocols, investigator brochures, and informed consent forms. Determine appropriate safety monitoring and risk management strategies. Ensure compliance with all applicable regulatory and ethical guidelines. Contribute to the preparation and submission of regulatory documents. Analyze and interpret clinical trial data to support decision-making. Participate in scientific conferences and present clinical trial results. Requirements: Medical degree and experience in Nephrology or a related field. Proven experience in clinical development within the pharmaceutical or biotech industry. Strong knowledge of renal diseases and related therapies. Excellent understanding of clinical trial design and execution. Exceptional communication and interpersonal skills. Ability to work effectively in a cross-functional and multicultural environment. Strong leadership and project management abilities. Proficiency in English, both written and spoken. Novartis offers a unique opportunity for a CDMD to contribute to innovative research and make a significant impact on patients' lives. Joining our team means working with individuals who demonstrate exceptional problem-solving skills and a dedication to collaborative work in a dynamic and driven environment. At Novartis we are committed to fostering diversity and inclusion. We are an equal opportunity employer (EOE) and value the contributions of individuals from all backgrounds. We strive to provide a work environment that promotes fairness, respect, and equal opportunities for growth and development. We also understand the importance of reasonable accommodations and adjustments for individuals with disabilities. If you require any accommodations or adjustments throughout the application process, please let us know, and we will ensure that your needs are met. Join a leading organization committed to revolutionizing healthcare through advanced research and inventive solutions. Apply today and contribute to our impactful work! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are looking for a currently enrolled Master student and can offer the rare opportunity to write a Master's thesis in our Data Science and Analytics Department. The task in a nutshell: Define the Data architecture of a solution elaborated in a project leveraging existing patterns. About the Role Data Architect - Internship We are looking for a Data Architect Intern to join our project team. The ideal candidate will have a strong understanding of data flow diagrams, data modelling, and data dictionaries. They will be responsible for designing consistent and efficient storage, integration, and access to data across the development process. Preferred Start Date : ASAP Duration : 6-12 months Key responsibilities: Design and maintain data flow diagrams, data models, and data dictionaries. Develop and implement data integration processes to combine data from multiple sources into a unified view. Establish relationships between data entities and set rules and standards for integration and interoperability. Ensure efficient data management and effective analysis/reporting to support business goals. Collaborate with various departments to ensure data architecture aligns with organizational objectives. Work Arrangement : Hybrid Minimum Requirements: Education : Currently enrolled in a Master's Degree in Computer Science, Information Technology, or a related field. Experience/Professional Requirements : Proven experience in data architecture, data modelling, and data integration processes. Desirable Requirements : Experience with data governance and metadata management. Familiarity with data storage solutions and data management tools Skills: Business Architecture. (Relito, Immuta) Enterprise Architecture. (Colibra) Data Quality (Ataccama) Data Governance. Solution Architecture. (databricks on AWS) Languages : Proficiency in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Novartis holds a rich development portfolio of small molecules ready to develop into innovative, patient centric, oral dosage forms. As a Drug Product Project Leader (DPPL) working on oral dosage forms, you will lead and manage formulation and manufacturing activities linked to pharmaceutical development for small molecules (New Chemical Entities; NCE). For this position, specific emphasis lies on bringing in-depth experience of pharmaceutical unit operations and related late-phase experience including scale-up and transfer to the commercial site. You will lead drug product teams during all stages of development with a specific focus on late clinical phases. You will be working on oral Small Molecules and in particular on enabling formulation approaches. You will use your strong communication, stakeholder management and influencing skills to effectively lead the drug product sub team and the transfer team in a matrix organization. Your expertise will facilitate the planning and execution of smart DoE and scale-up / transfer campaigns to establish robust manufacturing processes and stable drug products suitable for human trials and commercial supplies following ICH principles. About the Role Your responsibilities will include but are not limited to: You lead and manage all Drug Product (DP) related technical development activities for assigned projects and you represent DP project teams in Technical Research and Development (TRD) sub-teams based on your strong scientific and pharmaceutical development expertise. You lead, manage and support the DP and the transfer teams in line with Novartis values and behaviors. You build strong team spirit and promote knowledge exchange within and between teams. You motivate and coach team members for high performance. You formulate a sound DP project strategy incl. contingency planning and risk assessments as appropriate, involving functional experts, and you ensure alignment with Pharmaceutical Development department and other departments and functions inside and outside of TRD and 3rd parties as applicable. You ensure adherence to the scientific and project review process and through relevant scientific and project management governance boards You ensure creation of high quality and scientifically sound DP development documents enabling a strong CMC submission package, and act as author, reviewer or approver for development documents in accordance with operational procedures and guidelines. You contribute to the generation of registration dossiers, answer DP related questions in internal and external audits, and support Health Authority requests. What you’ll bring to the role: PhD in Pharmaceutical Sciences or relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 3 years of relevant technical experience in Development of oral Pharmaceutical Drug Products with proven experience in leading project teams in a matrix organization. Strong expertise in pharmaceutical oral dosage form development, manufacturing, and scale-up for formulations for Small Molecules including enabling formulations, manufacturing and IPC technologies, and scale-up principles. An understanding of material science principles, as applied to oral dosage forms, including the impact of physico-chemical properties of API and excipients on the drug product process and quality. Experience with application of Quality by Design and Quality risk management principles and tools as well as good working knowledge of regulatory guidelines relevant to Drug Product Development, validation, risk management, testing and stability, and new drug applications, together with technical writing and presentation skills. Ideally experience in applying data science, statistics, and DoE to enhance pharmaceutical development by providing a robust framework for data analysis, experimental design, and decision-making, leading to more effective and efficient drug development processes and documentation. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary 30 million! That is the estimated number of patients worldwide suffering from inflammatory arthritis. Join Novartis to help find the right drugs that transform and improve patients' lives all around the world. You will join an international team of clinicians and scientists making significant impact on autoimmune diseases with high unmet medical need, taking new medicines into early-stage clinical trials: in many cases you will be the first to witness the effectiveness of a new medicine that may transform the lives of millions. Your medical and scientific leadership / expertise will significantly impact the Novartis autoimmune drug development pipeline. Go to https://www.novartis.com/our-science and scroll to the Autoimmunity research area and Translational Medicine area for more information. Main purpose of the role: • Direct and develop the analysis of successful translation of non-human research to human clinical trials, conducts analysis of pathways to find links to diseases. • Identify and utilize the appropriate biomarkers to predict drug efficacy in humans or biological activity and new biomarker assays to support clinical trials and clinical development decision-making. • Select innovative therapies and shows proof of concept or other types of early signal detection. • Involve the integration of biomarker, genetic imaging and clinical safety information. Provide feedback in order to standardize the drug dosages and procedures for the manufacture of drugs and medicinal compounds. Please note - this is a 100% position for 2 years. About the Role Your responsibilities will include: Developing & implementing strategies for efficient, high value management of assigned drug development projects in liaison with appropriate line functions with the objective to get to the first clinical evidence and other types of early signal detection. Developing & implementing efficient, high value decision strategies for the Translational Medicine component of drug development projects focusing on the early clinical phase. Responsibility for the development & implementation (with support from Biomarker Development) of the compound related and Disease Area Biomarker strategies. Contributing to the clinical strategy & the early Clinical Development Plan. Acting as a cross-functional member for research and clinical teams What you’ll bring to the role: • MD and Board-certified Rheumatologist (or similar relevant sub-specialty clinical training with directly relevant patient experience) with PhD-level basic science. A completed relevant postdoctoral fellowship is strongly preferred. • Experience within Translational Medicine and a strong understanding of the relevant regulations and guidelines. • Advanced / business-level / fluent English (oral and written) Your behavioral characteristics • Demonstrated passion for treating patients and science • Results-driven self-starter and decision taker • Strong cooperative team player, flexible in a changing environment • Good planning, prioritization, problem solving and organisational skills • Resilient, energetic and enthusiastic, responding constructively to challenging new ideas and input Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Bringing life-changing medicines to millions of people, Novartis sits at the intersection of cutting-edge medical science and innovative digital technology. As a global company, the resources and opportunities for growth and development are plentiful including global and local cross functional careers, a diverse learning suite of thousands of programs & an in-house marketplace for rotations & project work. With strong medicines pipeline our current transformation will not just deliver growth for our business but continue to allow us to bring innovative medicines to patients quickly. The Global Clinical Imaging and Analytics Head will coordinate and lead the application of different imaging strategies to support our portfolio of innovative medicines spanning across oncology, cardiovascular, renal, immunology, and neuroscience. Will coordinate with cross-divisional multidisciplinary teams spanning clinical, data science and commercial functions to discover, develop, evaluate and implement innovative AI/ML derived imaging biomarkers/endpoint strategies across the Novartis portfolio. This role will collaborate extensively with internal and external stakeholders to access/leverage medical imaging data/platforms and build a Novartis high value portfolio and reputation in the fields of imaging technology and clinical radiology. About the Role Major accountabilities: Develop fit for purpose clinical imaging strategies/technologies for our clinical trials and ensure high quality training at clinical sites and to data acquisition Develop and lead unique Novartis strategies for mining internal and external medical image and device data to support innovative biomarker discovery, development and implementation in drug development across multiple therapeutic areas Leverage diverse knowledge and skillsets to fully integrate and effectively communicate with clinicians, epidemiologists, data scientists, imaging experts and software engineers to meaningfully advance translational research efforts, including integration into disease animal models and other “omics/phe-nomics” data sets, where appropriate, across multiple therapeutic areas Lead AI/Machine learning approaches to develop novel structural and functional biomarkers/endpoints from medical imaging and device data to enable better quantitation of common clinical parameters or improve diagnostics, sub-classify diseases and enable predictive patient risk/stratification Lead and partner to enable impact of data science derived imaging biomarker approaches in the early drug development portfolio for “Proof of Concept/Proof of Mechanism” with Translational Medicine across multiple therapeutic areas Partner and serve as a leadership team member with NVS data platform groups e.g. DATA42/Data Sciences and AI, to clarify the landscape of clinical needs, challenges and the scope of imaging/DICOM data available to enable new analytic approaches with existing radiology software suites as well as de novo deep learning models at the voxel level Collaborate with internal stakeholders to support the advancement of imaging data repositories and data collection technologies such that the data are of maximal value to NVS systems and processes. Shape NVS policies on imaging data storage, aggregation, harmonization, retention and application so that it is well positioned to benefit NVS now and in the future Lead collaborations with internal stakeholders across NVS e.g. Biomedical Research/Development - clinical, data sciences, Chief Digital Office/AI Innovation Center/DATA42 to fully leverage enterprise imaging and data science expertise, optimize our portfolio value and drive innovation Team management and responsibility for a group of 10-30 Associates Key performance indicators: Lead the discovery, advancement and qualification of specific imaging based biomarkers/endpoints which can deliver personalized medicine approaches across Novartis portfolio spanning over research and development programs, providing the highest value added medicines Enable BR and Dev to test biological and therapeutic hypotheses in clinical development, resulting in clear proof of concept/mechanism readouts, health authority endorsements, and commercial differentiation, potentially helping in successful program acceleration. Recognized internally and externally through publications, leading global strategies/teams and consortium impacts as a subject matter expert/leader for NVS Adherence to Novartis Values and Behaviors, especially innovation and collaboration Education/Experience : PhD/MD, preferably MD, board certified radiologist with clinical research and data sciences training and/or certification, as well as a deep understanding of clinical epidemiology that can be applied to questions of diagnosis, biomarker development and treatment monitoring 5 to 10 years professional/industry experience Extensive Clinical and Diagnostic Radiology experience in areas such as Cardiovascular, Immunology, Neurology, Renal and Oncology Experienced in medical multi-modality imaging platforms such as MRI, CT, PET and ultrasound Substantial impactful global experience developing and leading multidisciplinary matrix teams across Pharma/biotech (clinical research through healthcare applications), academic institutions, and commercial business functions Demonstrated technical and scientific expertise in multiple areas for development of innovative biomarker solutions Well-developed interpersonal skills with good presence and ability to influence and negotiate with senior leadership, experienced presenter and communicator Recognized internally and externally by key stakeholders; in depth understanding of external environment/trends; develops a strong professional network Languages: Fluent in oral and written English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards its-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland; Responsible for leading and developing a team as well as independently managing complex intellectual property (IP) administrative, filing and legal support tasks, including supporting patent practitioners in regional, international, and foreign patent filing. Provides expert knowledge and understanding of IP law and practice issues. Undertakes operational and strategic responsibilities to maximize the effectiveness of paralegal sup-port at a local and global level. Responsible for applying, maintaining and contributing to the improvement of the department best practices. Responsible for training others in all areas of European Patent (EP)/international and foreign patent matters. Pro-actively participates or leads a team within IP and Legal Support in areas of procedure develop-ment, improvement of current procedures and other efficiency initiatives. Leads and develops a high performing local team of patent paralegals, ensuring timely, complete and accurate filing and prosecution of all patent applications and patents in scope. Member of the Global Patent Support leadership team Manages resources to maximize efficiency and productivity of the team. About the Role Your responsibilities include, but not limited to : Files and supervises EP/international and foreign patent applications and related correspondence from filing to issuance of grant, including preparing all documents required in connection with EP, Patent Corporation Treaty (PCT) and foreign applications; proactively prepares simple responses to official communication and notifications. Maintains and shares expert knowledge of latest patent rules and adapting practices to comply and supervise or train patent support team members to ensure staff are knowledgeable and proficient in carrying out filing and prosecution procedures accordingly. Monitors electronic docket for responsible attorney(s) and assigned paralegal tasks on a daily basis ensuring that all related deadlines are met in a timely manner. Independently, proactively and critically reviews, maintains and assists responsible attorney(s)’ dockets and workload. Coordinates outsourcing, transfer in and transfer out of patent files and responsibilities in a timely and efficient manner, minimizing risk of loss of rights. Ensures that all appropriate documentation is completed in accordance with applicable procedures for each stage of patent filing and prosecution. Undertakes projects to address global patent prosecution and other patent support issues affecting the department. Communicates autonomously and effectively with team members, management, colleagues, inventors, foreign agents and other associates. Is a member of the Global Patent Support leadership team and actively participates in Patent Support and IP meetings. Role includes on an as needed basis the flexibility to provide support in other areas within the IP and Legal Support team (i.e. annuities, invoicing and data input). Leads or participates in teams developing procedures and processes, including process improvement to enhance efficiencies, including addressing global patent prosecution issues affecting the department. Conducts and chairs meetings. In line with Novartis Leadership principles, sets targets and objectives, monitors and manages workload and performance, conducts performance appraisals, and trains and coaches direct reports on site to ensure alignment and objectives are met Responsible for hiring and staffing the patent paralegal team on site. Responsible for training all new patent paralegals on site and dealing with other patents administrative staff to ensure that they are complying with Novartis best practices. What you'll bring to the role: Relevant degree, Law - Paralegal/equivalent IP certification or equivalent experience Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as a patent paralegal in a patent law firm or corporation with international and foreign filing experience. Ability to deal with a highly complex environment - manages workload and work product with high quality. Advanced knowledge and competency of patent database and report generating tools. Ability to work well and meet deadlines, without supervision, in an electronic office environment. Well-developed research and critical thinking skills, and sound decision-making abilities, with attention to detail to produce consistently accurate work Excellent analytical skills, organizational, and communication skills. Liaise with other cross-divisional groups to prevent duplication of effort and to ensure that effective knowledge sharing occurs. Demonstrates leadership qualities and ability to recruit, train, manage and develop IP paralegal team members and lead a local paralegal team as part of one cohesive IP Support team across all IP sites Knowledge of IP and document management systems and Microsoft Office Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10045696 Apr 23, 2025 Switzerland Summary The Scientific Data & Products (SDP) group in Research Informatics (RX) is driven to maximize the impact and value to BR of software and data. We deliver powerful, functional, beautiful, and integrated software solutions that create a frictionless user experience. Our organization is here to build and apply excellence in product and data management to further Novartis drug discovery. About the Role As a Data Architect you will design an efficient, elegant, and high-performance data architecture and flow of data through the data systems backing our scientific data products. You will work closely with colleagues in product management, data engineering, business analysis and user experience, data science, and information security and risk management teams to deliver on our product vision. You will create an efficient, secure, compliant, performant, and sustainable data landscape which will be crucial for successfully achieving RX-s strategic goal of democratizing access to BR-s data. Major Responsibilities Independently design enterprise-quality data architecture sitting behind our products Frequently update the design to reflect learnings from our agile product teams Factor in BR- and Novartis-wide data ecosystem impact Define, initiate and/or drive solutions that enable smooth user experience of data flow and connectivity through entire processes across scientific domains with enterprise level impact Advance and achieve very high level of adoption of RX and industry best practices by product teams Design, implement and maintain security/infrastructure requirements for development / testing environment, OR design, implement and keep technology stack of relevant products for development, test and production use support OR manage application infrastructure including application infrastructure design input, application installation and deployment and operational management of the application infrastructure Work in close collaboration with Architecture and Operations to integrate new solutions, ensuring timely and cost-effective delivery of solutions required for new projects and high integration of components Help to drive architectural improvements and standardization for the infrastructure/security environments. Develop and enhance automated processes to release new solutions into the live environment or create reusable and automation frameworks Ensure controls are in place for all configuration items and only authorized changes are made for all assets within enterprise IT environment Ensure creation of detailed solution/service design matching high level designs and functional specifications to meet quality and performance requirements and ensure the quality, cost and timelines of feature and product implementations OR install applications per approved designs, acting as DevOps lead ensuring infrastructure is deployed/developed to meet technical design, and operationally manage application infrastructure, taking preventive measures to avoid unplanned outages Major accountabilities: A successful candidate must have extensive expertise in data architecture and experience with scientific data types used in drug discovery including biology, chemistry, and clinical data. Additional skills are required in the area of process change management and with the alignment of non-IT scientists behind strategic data management goals and initiatives. The ideal candidate demonstrates the following skills and capabilities: Expertise in data architecture, data engineering, or software engineering Excellent knowledge in at least two of BR-s core data areas (molecular biology, chemistry/chemical biology, clinical) Experience with developing or supporting standard IT products used in these core data areas together with an excellent understanding of the data flows between those Proven experience with architecting IT solutions that enable laboratory data workflows on a global company level Balancing corporate and departmental priorities and goals on a global level Proven mindset that demonstrates an understanding of the needs of a global company-s digital journey Proven drive for ensuring data consistency Consensus-building skills and ability to win others in IT and science to follow a shared vision Proven ability to execute consistently, rapidly, and effectively Outstanding communication skills and excellent stakeholder management Proven ability to operate successfully at the challenging interface between research and development functions and aligning their diverse needs Expertise in identifying and/or creating initiatives that move the organization to new levels of effectiveness Ability to improve processes and methods across scientific domains and laboratory workflows Experience with agile software development Experience with linked data concepts, technologies, and tools Essential Requirements: Master-s degree (or equivalent experience) Excellent technical skills with at least 10 years experience as a data architect, data engineer, or software engineer 5+ years experience creating scientific software, or working in a drug discovery environment or related scientific field Proven experience in managing scientific domain-specific data and metadata Experience in the practice of agile software development processes Experience with distributed data processing and management systems Experience in working with ontologies and managing data described in RDF Experience with cloud technologies (AWS, Google, or Azure) Proficiency in English (Oral & Written) Desirable: Experience working with Graph databases is a plus ou-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams- representative of the patients and communities we serve. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Part time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Scientific Data & Products (SDP) group in Research Informatics (RX) is driven to maximize the impact and value to BR of software and data. We deliver powerful, functional, beautiful, and integrated software solutions that create a frictionless user experience. Our organization is here to build and apply excellence in product and data management to further Novartis drug discovery. About the Role As a Data Architect you will design an efficient, elegant, and high-performance data architecture and flow of data through the data systems backing our scientific data products. You will work closely with colleagues in product management, data engineering, business analysis and user experience, data science, and information security and risk management teams to deliver on our product vision. You will create an efficient, secure, compliant, performant, and sustainable data landscape which will be crucial for successfully achieving RX’s strategic goal of democratizing access to BR’s data. Major Responsibilities Independently design enterprise-quality data architecture sitting behind our products Frequently update the design to reflect learnings from our agile product teams Factor in BR- and Novartis-wide data ecosystem impact Define, initiate and/or drive solutions that enable smooth user experience of data flow and connectivity through entire processes across scientific domains with enterprise level impact Advance and achieve very high level of adoption of RX and industry best practices by product teams Design, implement and maintain security/infrastructure requirements for development / testing environment, OR design, implement and keep technology stack of relevant products for development, test and production use support OR manage application infrastructure including application infrastructure design input, application installation and deployment and operational management of the application infrastructure Work in close collaboration with Architecture and Operations to integrate new solutions, ensuring timely and cost-effective delivery of solutions required for new projects and high integration of components Help to drive architectural improvements and standardization for the infrastructure/security environments. Develop and enhance automated processes to release new solutions into the live environment or create reusable and automation frameworks Ensure controls are in place for all configuration items and only authorized changes are made for all assets within enterprise IT environment Ensure creation of detailed solution/service design matching high level designs and functional specifications to meet quality and performance requirements and ensure the quality, cost and timelines of feature and product implementations OR install applications per approved designs, acting as DevOps lead ensuring infrastructure is deployed/developed to meet technical design, and operationally manage application infrastructure, taking preventive measures to avoid unplanned outages Major accountabilities: A successful candidate must have extensive expertise in data architecture and experience with scientific data types used in drug discovery including biology, chemistry, and clinical data. Additional skills are required in the area of process change management and with the alignment of non-IT scientists behind strategic data management goals and initiatives. The ideal candidate demonstrates the following skills and capabilities: Expertise in data architecture, data engineering, or software engineering Excellent knowledge in at least two of BR’s core data areas (molecular biology, chemistry/chemical biology, clinical) Experience with developing or supporting standard IT products used in these core data areas together with an excellent understanding of the data flows between those Proven experience with architecting IT solutions that enable laboratory data workflows on a global company level Balancing corporate and departmental priorities and goals on a global level Proven mindset that demonstrates an understanding of the needs of a global company’s digital journey Proven drive for ensuring data consistency Consensus-building skills and ability to win others in IT and science to follow a shared vision Proven ability to execute consistently, rapidly, and effectively Outstanding communication skills and excellent stakeholder management Proven ability to operate successfully at the challenging interface between research and development functions and aligning their diverse needs Expertise in identifying and/or creating initiatives that move the organization to new levels of effectiveness Ability to improve processes and methods across scientific domains and laboratory workflows Experience with agile software development Experience with linked data concepts, technologies, and tools Essential Requirements: Master’s degree (or equivalent experience) Excellent technical skills with at least 10 years experience as a data architect, data engineer, or software engineer 5+ years experience creating scientific software, or working in a drug discovery environment or related scientific field Proven experience in managing scientific domain-specific data and metadata Experience in the practice of agile software development processes Experience with distributed data processing and management systems Experience in working with ontologies and managing data described in RDF Experience with cloud technologies (AWS, Google, or Azure) Proficiency in English (Oral & Written) Desirable: Experience working with Graph databases is a plus ou’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10051450 May 12, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director - Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No

Summary The Clinical Development Medical Director (CDMD) for Immunology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10050821 May 27, 2025 Switzerland Summary The Clinical Development Medical Director (CDMD) for Immunology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years- experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture&nbsp ; You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary ***Closing date for applications 6th June 2025 "We’re a team of dedicated and smart people united by a drive to achieve together" Embrace an exceptional career opportunity as our Director, CEO Strategic Affairs. In this pivotal role, you will drive the CEO's objectives, manage key communications, and meticulously plan annual top-leader meetings. You'll prioritize CEO engagement requests and shape engaging content across channels and manage the social media strategy. By strengthening collaboration with internal teams, you'll ensure alignment and visibility of CEO activities. Manage the CEO’s video filming schedule and support media engagements. You'll catalyze high-impact collaborations to advance both the Novartis brand and the CEO's reputation. This isn't just a job – it's a career-defining opportunity. Provide leadership in strategic planning, content creation, and foster relationships at Novartis. We're eager for your talent, ambition, and vision on the CEO Strategic Affairs team. About the Role Major Accountabilities • Leads the planning and organization of the company top-leaders in person meeting and virtual connects, in close communication and partnership with the Corporate Affairs & People & Organization functions. • Proactively identifies and prioritizes engagement requests for the CEO based on strategic importance and urgency, ensuring efficient organization and streamlined processes. • Identifies key themes and opportunities for CEO content creation across various channels (e.g., social media, Op Eds, Podcasts), that serve strategic objectives to enhance the Novartis brand, business and overall CEO communications. • Supports the development of internal presentations for the CEO, including briefing reports on business performance • Supports planning and delivery of other CEO engagements (internal and external), media engagements, mass mails, slides, talking points, scripts, in close partnership with Corporate Communications, Public Affairs and other teams, where applicable. • Leads the planning of video filming for the CEO (social media, requests, etc.), working closely with Corporate Marketing team for execution. • Brings innovative ideas, collaborates and aligns with the different Corporate Affairs teams to coordinate campaign strategies and general communications activities that impact CEO communications. • Tracks and maintains an editorial calendar for CEO engagements and content and ensures visibility and alignment across teams and partners. • Manage issues response effectively, where and when needed. • In close partnership with Corporate Affairs, manages regular, effective data reporting and analysis for CEO content and activities. Required Experience Essential Bachelors or Masters in relevant area (Communications, Journalism, English, Business, Marketing preferred). Fluency in English, with very strong verbal and writing skills Extensive experience in communications, public relations, or content marketing within a major corporation, trade association, or agency. Strong business acumen with an understanding of how to navigate a complex and multi-faceted landscape. Strong leadership skills with the ability to inspire, influence and challenge in the context of a matrix organization and towards strategic objectives. Proven knowledge and understanding of social media platforms and best practices. Experience in creating and executing engaging content campaigns that drive measurable engagement with key audiences. Proven experience in managing issues and media/social response strategies. Ability to manage stakeholder relationships, with credibility and the ability to interact with influencers and other key stakeholders. Proven track record in managing projects and achieving results through influence. Desirable Scientific or pharmaceutical background desirable Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help elucidate the metabolic aspects of chronic kidney disease onset and progression. You will be part of our Disease Area X team in Basel, Switzerland Chronic kidney disease (CKD) is a leading global health problem with a significant unmet medical need. CKD affects approximately 10% of the population worldwide and is expected to become the fifth leading cause of death in the upcoming decades. As a Discovery Postdoc you will have the opportunity to support our interdisciplinary efforts aimed at understanding the underlying metabolic alterations leading to disease onset and progression. You will apply state-of-the-art in vitro cellular models and characterize novel genetic mouse lines to investigate metabolic dysfunction and reprogramming in renal cell sub-populations upon injury. By leveraging cutting-edge -omics technologies you will have the opportunity to uncover novel mechanisms and pathways in CKD progression. As a Discovery Postdoc you will aim at publishing your findings in high-impact journals. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year (pending review by the Head of Biomedical Education & Innovation and the postdoc supervisor) Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Integrate in vitro and in vivo experimental findings with -omics data Deepen our understanding of metabolic reprogramming and alterations in renal cells Unravel novel mechanisms and pathways in CKD onset and progression Enable team success with a curious, proactive, enthusiastic and collaborative spirit Role Requirements : PhD in cell biology or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strong, hands-on in vitro (primary and / or complex cellular models) and in vivo expertise Experience in analyzing spatial-, single-cell- and / or other -omics datasets is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity Fluency in English (oral and written) . Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053368 May 28, 2025 Switzerland Summary We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. About the Role Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and help elucidate the metabolic aspects of chronic kidney disease onset and progression. You will be part of our Disease Area X team in Basel, Switzerland Chronic kidney disease (CKD) is a leading global health problem with a significant unmet medical need. CKD affects approximately 10% of the population worldwide and is expected to become the fifth leading cause of death in the upcoming decades. As a Discovery Postdoc you will have the opportunity to support our interdisciplinary efforts aimed at understanding the underlying metabolic alterations leading to disease onset and progression. You will apply state-of-the-art in vitro cellular models and characterize novel genetic mouse lines to investigate metabolic dysfunction and reprogramming in renal cell sub-populations upon injury. By leveraging cutting-edge -omics technologies you will have the opportunity to uncover novel mechanisms and pathways in CKD progression. As a Discovery Postdoc you will aim at publishing your findings in high-impact journals. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year (pending review by the Head of Biomedical Education & Innovation and the postdoc supervisor) Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together. Start date: September 1st 2025 Key responsibilities As a Discovery Postdoctoral Fellow, you will: Work independently as well as with interdisciplinary teams Integrate in vitro and in vivo experimental findings with -omics data Deepen our understanding of metabolic reprogramming and alterations in renal cells Unravel novel mechanisms and pathways in CKD onset and progression Enable team success with a curious, proactive, enthusiastic and collaborative spirit Role Requirements : PhD in cell biology or a related field Note that PhD students in the last year of their thesis work are eligible to apply. Applicants are only eligible to apply up to 2 years from the date of receiving their PhD (i.e. PhD degrees must have been awarded May 2023 or later). Strong, hands-on in vitro (primary and / or complex cellular models) and in vivo expertise Experience in analyzing spatial-, single-cell- and / or other -omics datasets is considered a plus Strong publication record or other scientific achievements (i.e. awards, patents, grants) Excellent analytical, communication, presentation and organizational skills Passion for fundamental exploratory research and boundless curiosity Fluency in English (oral and written) . Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director – Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite Novartis is seeking a Principal Scientist, Radiochemist in Basel, Switzerland, to join the Global Discovery Chemistry team. The role focuses on developing novel radioligand therapies for oncology, requiring a strong background in radiochemistry and collaboration within a dynamic team. Join us and help us discover breakthrough therapies for millions of patients worldwide! Key responsibilities: Collaborate in multidisciplinary teams to develop radioligand therapies, conduct research in radiochemistry, and perform quality control of radioligands. Responsibilities also include mentoring team members and contributing to scientific publications and patents. Qualifications and skills: Candidates should possess a PhD in chemistry or a related field, extensive experience in radiochemistry, and a passion for hands-on experimentation. Strong communication skills and the ability to work in a fast-paced environment are essential. About the Role The role : At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis’ purpose. We are looking for a highly motivated, passionate researcher with a strong scientific background in radiochemistry, a curious mindset. Cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapies (RLT) is essential. Join us and help reimagine medicine! Your responsibilities will include, but are not limited to: You will work in a highly collaborative and multidisciplinary project team to discover and develop novel radioligand therapies in the oncology disease area. Carry-out cutting-edge research in the areas of radiochemistry and radionuclides therapies, including developing and validating radiosynthesis protocols for new Ga-68 diagnostic and Lu-177 therapeutic radiopharmaceuticals. Take a lead role in proposing, evaluating, interpreting and validating new radiolabelling procedures with radiometals including the use of automation and advanced formulation development. Perform the quality control of radioligands by High Performance Liquid Chromatography (HPLC), Thin Layer Chromatography (TLC) and Size Exclusion Chromatography (SEC) in the radiochemistry lab environment and release the radioligands for in vitro and in vivo preclinical studies. Deploy novel technologies and collaborate with internal and external partners to progress our projects. Responsible for following implemented radiation safety regulations (e.g. trainings, dosimetry, release and disposal of radioactive waste). You will mentor, coach, and develop a dynamic team of scientific associates Discuss, communicate and present scientific results at project/group meetings, decision boards, and external conferences Contribute to patent inventorship and scientific publications In addition to pipeline project responsibilities, you will participate in global initiatives shaping the future of drug discovery at Biomedical Research. Minimum requirements and what you will bring to the role: A strong passion for hands-on chemistry experimentation in the laboratory, with the ability to critically interpret results, develop new experimental hypotheses, and make informed decisions. A PhD in chemistry or related life science discipline with specialized knowledge in radiochemistry, gained either during postdoctoral and/or industry work Extensive hands-on experience in radiochemistry including metal labelling (e.g. Ga-68, Lu-177) of peptides and proteins. Experience with F-18 and Ac-225 radiochemistry would be beneficial. A proven track record of initiating, leading, or significantly contributing to cutting-edge research in chemistry or life sciences. A mindset characterized by curiosity, creativity, collaboration, and openness to diverse thinking, along with a desire to develop yourself and others. Interest in disruptive technologies and scientific trends, such as data science and automation/miniaturization, and their application to drug discovery. Ability to work effectively in a fast-paced, team-oriented matrix environment. Excellent oral and written communication skills, along with strong influencing abilities. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10052675 May 27, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite Novartis is seeking a Principal Scientist, Radiochemist in Basel, Switzerland, to join the Global Discovery Chemistry team. The role focuses on developing novel radioligand therapies for oncology, requiring a strong background in radiochemistry and collaboration within a dynamic team. Join us and help us discover breakthrough therapies for millions of patients worldwide! Key responsibilities: Collaborate in multidisciplinary teams to develop radioligand therapies, conduct research in radiochemistry, and perform quality control of radioligands. Responsibilities also include mentoring team members and contributing to scientific publications and patents. Qualifications and skills: Candidates should possess a PhD in chemistry or a related field, extensive experience in radiochemistry, and a passion for hands-on experimentation. Strong communication skills and the ability to work in a fast-paced environment are essential. About the Role The role : At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to more people. How can we continue to advance our science to help patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) in Basel, Switzerland, we are at the core of Novartis- purpose. We are looking for a highly motivated, passionate researcher with a strong scientific background in radiochemistry, a curious mindset. Cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapies (RLT) is essential. Join us and help reimagine medicine! Your responsibilities will include, but are not limited to: You will work in a highly collaborative and multidisciplinary project team to discover and develop novel radioligand therapies in the oncology disease area. Carry-out cutting-edge research in the areas of radiochemistry and radionuclides therapies, including developing and validating radiosynthesis protocols for new Ga-68 diagnostic and Lu-177 therapeutic radiopharmaceuticals. Take a lead role in proposing, evaluating, interpreting and validating new radiolabelling procedures with radiometals including the use of automation and advanced formulation development. Perform the quality control of radioligands by High Performance Liquid Chromatography (HPLC), Thin Layer Chromatography (TLC) and Size Exclusion Chromatography (SEC) in the radiochemistry lab environment and release the radioligands for in vitro and in vivo preclinical studies. Deploy novel technologies and collaborate with internal and external partners to progress our projects. Responsible for following implemented radiation safety regulations (e.g. trainings, dosimetry, release and disposal of radioactive waste). You will mentor, coach, and develop a dynamic team of scientific associates Discuss, communicate and present scientific results at project/group meetings, decision boards, and external conferences Contribute to patent inventorship and scientific publications In addition to pipeline project responsibilities, you will participate in global initiatives shaping the future of drug discovery at Biomedical Research. Minimum requirements and what you will bring to the role: A strong passion for hands-on chemistry experimentation in the laboratory, with the ability to critically interpret results, develop new experimental hypotheses, and make informed decisions. A PhD in chemistry or related life science discipline with specialized knowledge in radiochemistry, gained either during postdoctoral and/or industry work Extensive hands-on experience in radiochemistry including metal labelling (e.g. Ga-68, Lu-177) of peptides and proteins. Experience with F-18 and Ac-225 radiochemistry would be beneficial. A proven track record of initiating, leading, or significantly contributing to cutting-edge research in chemistry or life sciences. A mindset characterized by curiosity, creativity, collaboration, and openness to diverse thinking, along with a desire to develop yourself and others. Interest in disruptive technologies and scientific trends, such as data science and automation/miniaturization, and their application to drug discovery. Ability to work effectively in a fast-paced, team-oriented matrix environment. Excellent oral and written communication skills, along with strong influencing abilities. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. *Please note that this is a part time job share position with a maximum 70% working time About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. 60-70% job position Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10029829 May 28, 2025 Switzerland Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. *Please note that this is a part time job share position with a maximum 70% working time About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. 60-70% job position Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Part time Employment Type Regulär Shift Work No

Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for an Early Portfolio Global Program Head (GPH). The Global Program Head is a key player in the strategic leadership of Novartis, inspiring action through transformative vision and robust strategies for our programs. They drive the entire program lifecycle, having sole accountability and responsibility to deliver enterprise value by defining the program’s strategic vision, optimizing life cycle management, and driving the integrated development plans to ensure successful regulatory and access outcomes. As an integrative leader, the GPH represents the program internally and externally, embodies its values, maintains program commitments, and safely navigates the complex, ever changing healthcare landscape to deliver innovative medicines that improve and extend patients’ lives. Their role includes managing the Global Program Team, fostering career growth and equally emphasizing performance accountability within a high-performance and collaborative environment. The GPH holds a crucial and pivotal role in managing stakeholder relationships using exceptional communication skills, effectively influencing and involving stakeholders in decision-making processes, and anticipating and flexibly adjusting strategies to meet stakeholder expectations and responses. This role can be based in Basel Switzerland or East Hanover, US. About the Role Major Accountabilities Strategic Leadership Drive the program's transformational vision, devise an adaptable strategy that anticipates future trends and challenges, and translate strategies into practical, impactful plans. Seek out and combine complex internal/external elements to inform business decision-making, identify key issues in complex scenarios, and ensure clarity. Embody an enterprise leader that works across the entire Novartis research-development-commercial continuum to understand the impact of decisions, the benefit of diverse perspective, and the power of our shared purpose. Deliver organization-wide impact through an understanding and respect for an evolving technological landscape, including knowing when and how to incorporate new tools into existing strategies while evolving ahead of anticipated capabilities (e.g., precision medicine, AI, blockchain, nanotechnology). End-to-End Program Lifecycle Accountability The GPH has sole accountability of and responsibility to deliver enterprise value by defining the asset’s strategic vision, optimize life cycle management, and drive the integrated development plans to ensure successful regulatory and access outcomes. Leads the design of the Target Product Profile (TPP) and the Integrated Development Plan (IDP). Accountable for end-to-end program leadership, including formally representing the program internally and externally, instigating innovation in early-stage development processes, issuing recommendations, making decisions to ensure the program success and asset value optimization, and ultimately propelling the program through preliminary testing and approval stages. Uphold regulatory compliance and meet initial stage commitments regarding prototype quality, timeline, projected cost, and potential value. Candidly communicate program impact projections and assess the early-stage commercial viability. Together with the Line Functions, Managing and Developing the Global Program Team Empower the team through clear roles/responsibilities, prioritizing individual growth, and holding team accountable for ambitious goals. Nurture a well-performing team that fosters collaboration and supportive challenge. Stakeholder Management Maintain positive relationships with stakeholders, ensuring clear, concise communication throughout the program lifecycle, and handle conflicts diplomatically. Build positive relationships with stakeholders; provide clear, concise communication about preliminary venture details and expertly navigate any arising conflicts. Enhance stakeholder understanding of program objectives/risks, influence their expectations through scientific and evidence-based communication, and involving stakeholders in decision-making processes. Adjust strategies based on stakeholders' needs, expectations, and potential responses. Foster stakeholders' understanding of project aims and inherent risks during initial development, shape their expectations through scientific evidence-based dialogue, and include them in decision-making processes. Adapt strategies by anticipating stakeholders concerns, needs, and possible responses. Education Minimum requirements Doctoral degree or equivalent, MD preferred Min 8 years of drug development experience, including experience in dossier submission for new or supplemental indication Exposure to full drug development lifecycle Managing cross-functional teams and intense cross-functional collaboration and alignment Leading teams through influence without direct authority Communicating clearly and concisely with various audiences, adjusting messaging, style, tone, and details to best fit different audiences Experience in forming and driving transformative visions and strategic plans for early-stage programs. Background in team management, developing roles, and fostering a high-performance culture. Previous interactions with early stage/scientific stakeholders, emphasizing clear communication and involvement in decision-making. Experience in anticipating and crafting adaptive, resilient strategies for early-stage innovation and scenario planning. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Senior Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Sr CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 10 years of experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are seeking a motivated QC-Analyst for Biopharmaceutical Production within the framework of raw materials, drug substance, and in-process controls. The candidate will perform analytical testing and ensure compliance with SOPs, analytical methods, and compendial standards. About the Role Major accountabilities: · Conduct and coordinate quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements · Independent planning, implementation, and evaluation of routine and special analyses in a GMP-regulated environment · Interpret test data, prepare detailed reports, and maintain accurate record of test results. · Troubleshoot testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis · Conducting microbiological tests such as total germ count determinations (MET) and bacterial endotoxins (BET) · Participate in the validation of analytical procedures · Collaborate closely with the internal teams to optimize quality control processes · Instrument responsibilities, including qualification, maintenance, and calibration documentation · Support in ensuring that the laboratory is maintained in a ready state of inspection. Key performance indicators: · Timely test record completion and accurate processing without delays · Prompt reporting of missed deadlines and aim for shortest possible lead times · Continuous readiness for inspection · Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities · Proactively identify and implement cost-reducing optimizations · Complete all assigned training as per the provided plan Minimum Requirements: · Completed scientific education (e.g., Laboratory Technician, Bachelor or Master) · Practical experience in a GMP-regulated lab and document creation · Knowledge in common analysis techniques, especially HPLC and photometry; microbiological knowledge is an advantage · Working experience in laboratory environment in the pharmaceutical industry · Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage · Ability to work precisely, independently, and proactively · Reliability, flexibility, resilience, and strong teamwork skills · Shift work with normal working times (one shift) including weekends Skills: · Continuous learning · Dealing with ambiguity · Decision making · GMP · Industry standards · Laboratory equipment · Laboratory excellence · Quality Control (QC) testing · Quality Control sampling · Self awareness · Technological expertise Languages : · Fluent in German (spoken and written) and proficient in English Skills Desired Continued Learning, Dealing With Ambiguity, Decision Making Skills, Gxp, Industry Standards, Laboratory Equipment, Laboratory Excellence, Quality Control (Qc) Testing, Quality Control Sampling, Self-Awareness, Technological Expertise Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As our Clinical Development Medical Director in our Immunology Development Unit you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. About the Role The Clinical Development Medical Director (CDMD) for Rheumatology is the clinical leader of defined program level activities (e.g., submission activities, briefing books etc.), or a large, complex trial, under the leadership of the (Sr.) GPCH. May lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase) Your responsibilities include, but are not limited to: • Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) • Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates • Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor • Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety • Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. • Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) • Work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters • Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support • Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. • May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: • MD (or equivalent medical degree) is required. • Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred • Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. • 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. • 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment • Showcase advanced knowledge of assigned therapeutic area • Demonstrate ability to establish strong scientific partnership with key partners • Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process • Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. • Exhibit excellent business communication and presentation skills • Possess strong interpersonal skills • Adept with excellent negotiation and conflict resolution skills Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons. This hybrid role can be based in Basel, London, Barcelona, Madrid or Dublin. R ead our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10054184 Jun 04, 2025 Switzerland Summary -Equipment Operator -Execute assigned manufacturing tasks and activities according to production schedule to enable the timely production of product with the quality and quantity in compliance with the relevant GMP, safety and environmental guidelines. -Service Operator -Execute assigned manufacturing tasks and activities according to production schedule in compliance with the relevant GMP, safety and environmental guidelines.Perform routine operational support activities according the manufacturing process and schedule and enable the timely production of product with the quality and quantity -Documentation Specialist Admin -The Documentation Specialist Admin manages the modification, editing, distribution, review and archiving of GMP manufacturing documents and the edition of the Batch records in order to deliver them to Production in the quality and within the deadlines. The Documentation Specialist Admin ensures a set of administrative tasks necessary for the proper functioning of the unit. About the Role Major accountabilities: Equipment Operator -Participation to the manufacturing processes -Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines. Key performance indicators: Deadlines: compliance with production planning, execution of tasks on time -Quality: Amount of errors in production documents edited or updated and in batch record review -Time management for shop floor where required Minimum Requirements: Work Experience: Operations Management and Execution. Collaborating across boundaries. Functional Breadth. Skills: Transportation. General HSE Knowledge. Knowledge of GMP. Art Curator. Transportation Classification (i.e. IATA or DOT) expertise. Manufacturing Process Execution. Languages : German Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary -Equipment Operator -Execute assigned manufacturing tasks and activities according to production schedule to enable the timely production of product with the quality and quantity in compliance with the relevant GMP, safety and environmental guidelines. -Service Operator -Execute assigned manufacturing tasks and activities according to production schedule in compliance with the relevant GMP, safety and environmental guidelines.Perform routine operational support activities according the manufacturing process and schedule and enable the timely production of product with the quality and quantity -Documentation Specialist Admin -The Documentation Specialist Admin manages the modification, editing, distribution, review and archiving of GMP manufacturing documents and the edition of the Batch records in order to deliver them to Production in the quality and within the deadlines. The Documentation Specialist Admin ensures a set of administrative tasks necessary for the proper functioning of the unit. About the Role Major accountabilities: Equipment Operator -Participation to the manufacturing processes -Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines. Key performance indicators: Deadlines: compliance with production planning, execution of tasks on time -Quality: Amount of errors in production documents edited or updated and in batch record review -Time management for shop floor where required Minimum Requirements: Work Experience: Operations Management and Execution. Collaborating across boundaries. Functional Breadth. Skills: Transportation. General HSE Knowledge. Knowledge of GMP. Art Curator. Transportation Classification (i.e. IATA or DOT) expertise. Manufacturing Process Execution. Languages : German Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053707 Jun 04, 2025 Switzerland Summary Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Tätigkeitsbeschreibung Unterstützung bei Internen und externen Audits Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten Genehmigungen für Wartung/Kalibrierung/Projekte einholen Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten Aktualisierung des computerisierten Wartungsmanagementsystems (SAP) nach Abschluss der Wartung/Kalibrierung Dokumentation der Ausführung der Kalibrierung Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich Angewandte Geschäftseinblicke Digitales & technisches Know-how Betriebliche Exzellenz Projekt-Exzellenz Bildungsabschluss Abgeschlossene Berufslehre als Automatiker Business-Networking SAP Software-Fehlerbehebung Kenntnisse über GMP Gesamte produktive Instandhaltung Allgemeines HSE-Wissen Sprachen Fliessende Englischkenntnisse und Beherrschung der Landessprache Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Functional Area Technical Operations Job Type Full time Employment Type Befristet (Befristet) Shift Work No

Summary At Health – Safety – Environment (HSE), we are looking for a motivated and committed intern from July 1, 2025 for at least 6 months, who wants to gain insight into HSE processes at a production site and actively support us. About the Role At Health – Safety – Environment (HSE), we are looking for a motivated and committed intern from July 1, 2025 for at least 6 months, who wants to gain insight into HSE processes at a production site and actively support us. Preferred start date: asap Latest start date: August 1, 2025 Duration: min. 6 months Languages required: German and English Key responsibilities: Support in health risk assessments at the workplace Support in internal HSE relevant programs and training, as well as general health, safety, and environmental topics Conducting occupational hygiene measurements across the entire site (noise, light, exposure measurements, and fit-test training (seal checks of respiratory masks)) Essential requirements: Education: Bachelor/Master Student or recent postgraduate in health protection, natural sciences or technical fields Languages: German and English Open communication and commitment Very good general computer skills (especially Microsoft Word & Excel) Please submit a cover letter that includes your motivation for the position and from when you will be available. Thank you. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Tätigkeitsbeschreibung • Unterstützung bei Internen und externen Audits • Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung • Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten • Genehmigungen für Wartung/Kalibrierung/Projekte einholen • Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren • Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten • Aktualisierung des computerisierten Wartungsmanagementsystems (SAP) nach Abschluss der Wartung/Kalibrierung • Dokumentation der Ausführung der Kalibrierung • Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich • Angewandte Geschäftseinblicke • Digitales & technisches Know-how • Betriebliche Exzellenz • Projekt-Exzellenz Bildungsabschluss • Abgeschlossene Berufslehre als Automatiker • Business-Networking • SAP • Software-Fehlerbehebung • Kenntnisse über GMP • Gesamte produktive Instandhaltung • Allgemeines HSE-Wissen Sprachen Fliessende Englischkenntnisse und Beherrschung der Landessprache Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary •Gerätebediener •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. •Service-Operator •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität •Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You’ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. WhyNovartis? 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary -Supports all activities within the assigned Quality department. Contributes to the implementation, maintenance, and execution of the assigned Quality and/ or Laboratory Systems in an effective and compliant manner. About the Role Major accountabilities: Provides technical and/ or administrative support to the Quality Organization. Performs simple, routine, repetitive activities as directed by supervisor. Follows Standard Operating Procedures (SOPs) and/or Laboratory Methods in an effective and compliant manner. Provides assistance in the preparation of documents (e.g. reports, records, presentations). Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable) Key performance indicators: Customer satisfaction -punctuality rate -Jobs done on time, following the specified cycle time -Consistent compliance with GMP and Health, Safety and Environment guidelines and Standard Operating Procedures -No complaints with regulatory inspections Minimum Requirements: Work Experience: Technical knowledge. Collaborating across boundaries. Operations Management and Execution. Skills: Continuous Learning. Dealing With Ambiguity. Gmp Procedures. Qa (Quality Assurance). Quality Control (Qc) Testing. Quality Standards. Self Awareness. Technological Expertise. Languages : German and English fluent Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Wartungstechniker I (Cell and Gene Therapy) Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Hauptverantwortlichkeiten Strategie & organisatorische Entwicklung Unterstützung bei Internen und externen Audits Wartung & Kalibrierung Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten Genehmigungen für Wartung/Kalibrierung/Projekte einholen​ Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten Aktualisierung des Computerisierten Wartungsmanagementsystems (CWMS) nach Abschluss der Wartung/Kalibrierung Dokumentation der Ausführung der Kalibrierung​/Wartung Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich, Herstellung von Teilen für schnelle Reparaturen und Verbesserungen) Key Performance Indicators Wartungstechniker I Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmearbeiten für Projekte auf Standortebene. Was Sie für die Position mitbringen: Bildungsabschluss als Elektriker oder Automatiker oder gleichwertiger Bildungsabschluss. Kalibrier Erfahrung Einschlägige Erfahrung wünschenswert, vorzugsweise in der Pharmaindustrie. Digitales & technisches Know-how. Bereitschaft für Schicht/Pikettdienst. Microsoft Office (Word, Excel etc.) Teamarbeit Kenntnisse über GMP SAP Kenntnisse Allgemeines HSE-Wissen Betriebswirtschaftliches Arbeiten Sprachen: Fließende Englisch- und Deutschkenntnisse. Skills Desired Kalibrier Erfahrung, Allgemeines HSE-Wissen, Business Networking, Effizienz, Einschließlich BIP, Employee Welfare, Fertigungsproduktivität, Gebäudetechnik, Kenntnisse über GMP, Mathematische Optimierung, Microsoft Word, Physik, Qualification, Software Troubleshooting, Team Work, Test Equipment, Total Productive Maintenance, Zusammenarbeit Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10052341 May 16, 2025 Switzerland Summary Wartungstechniker I (Cell and Gene Therapy) Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Hauptverantwortlichkeiten Strategie & organisatorische Entwicklung Unterstützung bei Internen und externen Audits Wartung & Kalibrierung Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten Genehmigungen für Wartung/Kalibrierung/Projekte einholen Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten Aktualisierung des Computerisierten Wartungsmanagementsystems (CWMS) nach Abschluss der Wartung/Kalibrierung Dokumentation der Ausführung der Kalibrierung/Wartung Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich, Herstellung von Teilen für schnelle Reparaturen und Verbesserungen) Key Performance Indicators Wartungstechniker I Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmearbeiten für Projekte auf Standortebene. Was Sie für die Position mitbringen: Bildungsabschluss als Elektriker oder Automatiker oder gleichwertiger Bildungsabschluss. Kalibrier Erfahrung Einschlägige Erfahrung wünschenswert, vorzugsweise in der Pharmaindustrie. Digitales & technisches Know-how. Bereitschaft für Schicht/Pikettdienst. Microsoft Office (Word, Excel etc.) Teamarbeit Kenntnisse über GMP SAP Kenntnisse Allgemeines HSE-Wissen Betriebswirtschaftliches Arbeiten Sprachen: Fließende Englisch- und Deutschkenntnisse. Skills Desired Kalibrier Erfahrung, Allgemeines HSE-Wissen, Business Networking, Effizienz, Einschließlich BIP, Employee Welfare, Fertigungsproduktivität, Gebäudetechnik, Kenntnisse über GMP, Mathematische Optimierung, Microsoft Word, Physik, Qualification, Software Troubleshooting, Team Work, Test Equipment, Total Productive Maintenance, Zusammenarbeit Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Functional Area Technical Operations Job Type Full time Employment Type Regulär Shift Work No