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Novartis AG

Novartis bietet innovative medizinische Lösungen an, um damit auf die sich verändernden Bedürfnisse von Patienten und Gesellschaften einzugehen. Novartis, mit Hauptsitz in Basel (Schweiz), verfügt über ein diversifiziertes Portfolio, um diese Bedürfnisse so gut wie möglich zu erfüllen: mit innovativen Arzneimitteln, Produkten für die Augenheilkunde und kostengünstigen generischen Medikamenten. Novartis ist das einzige Unternehmen mit weltweit führenden Positionen in diesen Bereichen.
Novartis bietet innovative medizinische Lösungen an, um damit auf die sich verändernden Bedürfnisse von Patienten und Gesellschaften einzugehen. Novartis, mit Hauptsitz in Basel (Schweiz), verfügt über ein diversifiziertes Portfolio, um diese Bedürfnisse so gut wie möglich zu erfüllen: mit innovativen Arzneimitteln, Produkten für die Augenheilkunde und kostengünstigen generischen Medikamenten. Novartis ist das einzige Unternehmen mit weltweit führenden Positionen in diesen Bereichen.
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18.07.2024

Novartis AG

Medical Director - Dermatology Translational Medicine

  • Novartis AG

  • Basel

  • 18.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID 392731BR Feb 27, 2024 Switzerland About the Role 350 million! That is the estimated number of patients worldwide suffering of atopic dermatitis or psoriasis. Join Novartis to help find the right drugs to transform and improve patient's lives all around the world. You will provide medical and scientific leadership and expertise in a role that significantly impacts the entire Novartis Dermatology drug development pipeline. • Drive success of early global programs, develop and implement strategies to achieve clinical Proof of Concept or Proof of Mechanism to enable transition to further development • Drive success of late global programs when appropriate by developing and implementing strategies that lead to clinical pharmacology, design of mechanistic studies and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling • Provide scientific expert assessments and support for in-licensing opportunities, including due diligences Your responsibilities: Translational Medicine early clinical projects: In collaboration with your Translational Medicine Therapeutic Area Head or other Translational Medicine Experts • Develop high value decision-strategies for the Translational Medicine component of drug development projects from Research to clinical Proof of Concept or Proof of Mechanism in a single or multiple indications, including Parallel Indication Expansion-Proof of Concepts - Represent TM and lead global project teams through First in Human and Proof of Concept phase to drive strategy that enables development - In collaboration with research scientists, contribute to the proposal of new targets or indications for existing compounds; identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities - Responsible for implementing studies during the Proof of Concept phase by providing medical and scientific leadership and expertise to all line functions on the project team. This may include methodology studies to identify and validate novel endpoints for early decision making. - Responsible for clinical portions of the Integrated Development Plan, including the Clinical Development Plan and Clinical Pharmacology Plan • Accountable for compound and disease related biomarker strategies, working closely with Biomarker Experts in implementation • Develop and implement study protocols for different types of clinical studies (First in Human, Proof of Concept, mechanistic and safety studies), and other documents such as investigators brochures. • Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study • Provide medical and scientific leadership and expertise to all line functions on the study team • Leadership - Lead study-specific teams/ clinical trial teams - Represent TM or lead BR project teams • Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders (e.g. payers, patient advocacy groups) • Represent clinical Translational Medicine in reviews of external opportunities • Oversee publication and external presentation of study results • Innovation: Champion and drive new clinical compound characterization opportunities and profiling approaches • Contribute to initiatives that drive innovation, quality, and efficiency across Translational Medicine Translational Medicine late-stage clinical projects: In collaboration with your Translational Medicine Disease Area Head: • Drive analysis of studies and present results to relevant decision boards • Communicate clinical team matters to Global Project Teams, relevant Novartis BioMedical Research and Global Development boards, and other Novartis Boards as required. • Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders • Provide support for dose selection, design and other clinical pharmacology matters throughout the development cycle • Responsible for content and authoring of documents needed for submission documents with Translational Medicine input (CO, SCE, SCS, SCP, SBP) of NDAs, sNDAs, MAAs, BLAs from regulatory submission through drug registration, including advisory committee and scientific advice group meetings Key Performance Indicators: • Delivery of proposed Development Candidates, Integrated Development Plan Approval and Development transition point milestones, and early clinical study results, according to timelines • Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results • Strong adherence to and modeling of Novartis values and behaviors • Quality of contribution to disease area strategy discussions and contribution to Clinical Pharmacology plans / Profiling strategy discussions and external collaborations Matrix people responsibility per project: 5-8 cross-functional members from within Translational Medicine plus other line functions per project team Impact of this role? • Design and implementation of early Clinical Development Plan and studies according to the Integrated Development Plan / Clinical Development Plan / Clinical Pharmacology Plan enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds • This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via First in Human, Proof of Concept, and driving the program after Proof of Concept by delivering key Profiling data to support regulatory submissions • Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis as well as country organizations as appropriate Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements What you’ll bring to the role: • Medical Degree and additional PhD/post-doctoral equivalent immunology research • Specialized further training (board certification) and / or clinical research experience in dermatology / immunology preferred • Advanced / business-level / fluent English (oral and written) • Recognized for medical expertise: demonstrated excellence and clinical / patient expertise in dermatology / immunology • Recognized for scientific expertise: respected by colleagues internally and externally, you’ve made significant contributions to your field and created / established new concepts; record of high quality publications in international scientific journals. • Previous relevant & significant clinical study experience: either from pharma/biotech leading early phase clinical trials; a senior role within a CRO responsible for leading the medical relationship with Sponsors; from a relevant academic medical center with PI & co-PI clinical trial experience. You are used to working independently and within teams including scientists and non-scientists on study planning and execution, demonstrating competence in a broad range of project and more strategic planning skills • Excellent written and oral communication/presentation skills, used to distilling and effectively conveying significant messages to different audiences Your behavioral characteristics • Demonstrated passion for treating patients and science • Strategic thinker: you have created major innovations, networked with and influenced external medical leaders with your clear and logical presentation of complex strategic issues • Innovation: a curious mind and a natural instinct to seek out new clinical discovery opportunities and clinical study approaches • Results-driven self-starter and decision taker; good planning, prioritization, problem solving and organizational skills; strong cooperative team player, flexible in a changing environment; Resilient, energetic and enthusiastic; responding constructively to challenging new ideas and input This position is written for Director - we can hire Executive Director for those with significant Pharma careers, or Associate Director if you have limited clinical study experience or a less established scientific record but have already demonstrated impactful new thinking and innovative clinical & scientific approaches within your career. ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Translational Medicine Location Switzerland Site Basel Company / Legal Entity Novartis Pharma AG Functional Area Research & Development Job Type Full Time Employment Type Regular Shift Work No Apply to Job(link is external)Access Job Account(link is external)
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17.07.2024

Novartis AG

Data Science Innovation Fellow

  • Novartis AG

  • Basel

  • 17.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013704 Jul 01, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! You will be embedded in the Oncology Data Science team and will work on large-scale representation learning approaches to conceptualize and develop cancer foundation models and contribute to the oncology target identification and drug discovery processes, with a specific focus on gastrointestinal cancers. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Develop and train large AI models on massive biological data collections (e.g. scRNA-seq data from cancer patients) to guide target discovery, biomarker characterization and patient stratification, with specific focus on gastrointestinal cancers. Apply state-of-the-art AI approaches to address bottlenecks in biomarker and target discovery, as well as clinical development decision-making. Work at the intersection of deep learning and drug discovery to address key scientific questions. Collaborate closely with cross-functional teams within Novartis Biomedical Research on applications of foundation models. Keep ahead of the latest developments in the field and bring curious and critical thinking to the team. Publish in top-tier scientific journals, present results at internal and external scientific venues. Role requirements : PhD in Computer Science, Machine Learning, Applied Mathematics, Computational Biology or a related field (PhD students in the last year of their thesis work, are eligible to apply). Strong programming experience in python and proficiency in at least one main deep learning framework (PyTorch/TensorFlow/JAX). Proven experience in implementing state-of-the-art machine/deep learning algorithms. Scientific publications in AI/ML conferences and/or in journals with a focus on computational biology/medicine. Ability to clearly communicate technical concepts to a variety of audiences, including scientists and subject matter experts from other domains. Familiarity with working on high-performance computing systems and/or cloud computing environments. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfil your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Study Start-up Lead

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012156 Jul 11, 2024 Switzerland Summary We are seeking a Study Start-Up (SSU) Lead to plan and execute global SSU activities to ensure timely trial document and task completion to enable country HA (Health Authorities) and Ethics Committee submissions and site activation to meet ambitious recruitment plans. This role will work directly with the Study & Site Operation (SSO) team and reports to the Study Start-Up Director. About the Role Key Responsibilities: Contributing SSU insights to the development of the trial Operational Execution Plan (OEP) and aligns the SSU plan and strategy accordingly as reflected in SSU systems, milestones and dashboards with Study Leader/Clinical Trial Team (CTT). Configuring and ensuring proper trial-specific set-up of SSU systems (e.g., Expected Document Lists, eTMF, milestones, tasks, personnel, vendors, languages/translations, confirmed and back-up countries, CTMS (Clinical Trial Management System), enrollment plan, vendor management tool, site contracting and budgeting tool, ICF template tool, etc.) Ensuring timely collection global trial level document readiness (including vendor and Investigational Medicinal Product) and collection into eTMF as necessary for country health authority and Ethics Committee submission and site activation. Supporting the Vendor Program Manager (VPM) as needed to ensure timely global vendor activation and HA submission documents. Enabling country Study Start-up Managers to drive timely start-up activities from country allocation to “Ready to Enroll” within assigned trial. Ensuring global deliverables to enable site initiation readiness is in place for initial drug release. Essential Requirements: Degree in scientific or health discipline. Fluency in English (both written and oral). Experience in clinical operations in a role that oversees (project management) and/or with monitoring clinical trials. Contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry or a contract research organization. Proven ability to effectively engage and lead associates from varying backgrounds and functions within dispersed and highly matrixed organizations. Excellent communication, influencing and negotiating skills. Good knowledge of Good Clinical Practice, clinical trial set-up design and global drug development process. Demonstrated effective influencing and negotiation skills at all levels. Desirable Requirements: Advanced degree with clinical trial experience and/or project management. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Strategy Director, Clinical Development

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10010244 Jul 04, 2024 Switzerland Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for a Strategy Director, Clinical Development. About the Role The purpose of the Strategy Director Clinical Development will be to support the crafting and execution of portfolio strategy and clinical program/functional excellence by actively partnering with the Head of Portfolio Strategy and Operations, Clinical Development Functional Heads, Head of Clinical Workforce Insights, Head of Program Capability and Quality, Head of Advanced Methods and Centers of Excellence, and Head of Data Design and Clinical Innovation. The Strategy Director may deputize for Head of Portfolio Strategy and Operations within Clinical Development and with a wide range of cross-functional teams. What you will be doing: Undertake diagnostics, study and analysis as required, suggest recommendations and drive resultant actions as approved. Continuously looks for new and better ways to deliver Clinical Development (CD) agenda. Prepares content for pivotal initiatives on behalf of the Head of Clinical Development/Head Portfolio Strategy & Operations. Support the streamlining and provide governance co-leadership for the Head Portfolio Strategy and Operations CD, ensuring consistent messaging across various governance forums (DevLT, CD LT). Support the build of the CD organization, creating and tracking meticulous and quantifiable objectives and communications; to support CD embedding best in class approaches to clinical development while growing deep therapeutic expertise. Lead on the benchmarking of CD activities at Novartis vs. peers Helps shape, influence and lead on functional strategy related activities and requests e.g., cross functional activities such as SRC governance with Global Medical Affairs, new initiatives to strengthen Development and CD, requests from Strategy Program Portfolio Operations. Represents the Head of Portfolio Strategy and Operations with cross-functional teams and within Clinical Development where needed. Supports the annual Clinical Development Strategy Review and objectives setting in collaboration with the CD Head, Clinical Development Heads and CD functional heads. Helps maintain updated CD program and above program reviews for, e.g., IMB, DevLT partnering closely with functional leaders. Ensure connectivity with global line functions to establish CD leadership amongst related functional teams, to ensure objectives are met, as mandated by DevLT/IMB. For example, work with Methods Head to establish IEP review process, work with Program Excellence & Capability Head to establish and embed Integrated Data Review, work with Data Design & Clinical Innovation head to help establish protocol AI. Supports the Head of Portfolio Strategy & Operations, to establish relationships and reinforce CD as single point leader for clinical programs, including Global Clinical Operations, Analytics, and Global Medical Affairs. Provides analytic insights into potential S&G, M&A and BD&L initiatives to evaluate from clinical perspective new opportunities Responsible for effective internal and external communication co-ordination on initiatives led by CD that warrant white papers or other external communication, e.g. updates to DevLT, IMB, Leadership forums. Navigates complexity and drives effectiveness across the function and in collaboration with other functions in Novartis Work closely with Head of Operational Excellence, Clinical Development Function Heads, head of Clinical Workforce Insights, Head of Capabilities, Engagement Lead. What you will bring to the role: Master degree or equivalent advanced degree or equivalent education/degree in life science/healthcare preferred (MD, PhD) -5 years people and matrix management required. Global people management experience desirable. Strong relationship builder and communicator with experience leading diverse work teams, driving program excellence, engaging functional partners Previous work and leadership in international and multidisciplinary drug development teams Strong knowledge of drug development strategy, Novartis experience in this area is preferred. Strong planning and project management skills Organizational awareness, including meaningful experience working cross-functionally and in global teams. Strong written & verbal communication coupled with excellent problem-solving, negotiation and conflict resolution skills. Strong communication skills with excellence understanding of presentation tools Experience in Consulting/Banking (Healthcare focus) preferred. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Strategy Director, Clinical Development

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10010244 Jul 04, 2024 Switzerland Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for a Strategy Director, Clinical Development. About the Role The purpose of the Strategy Director Clinical Development will be to support the crafting and execution of portfolio strategy and clinical program/functional excellence by actively partnering with the Head of Portfolio Strategy and Operations, Clinical Development Functional Heads, Head of Clinical Workforce Insights, Head of Program Capability and Quality, Head of Advanced Methods and Centers of Excellence, and Head of Data Design and Clinical Innovation. The Strategy Director may deputize for Head of Portfolio Strategy and Operations within Clinical Development and with a wide range of cross-functional teams. What you will be doing: Undertake diagnostics, study and analysis as required, suggest recommendations and drive resultant actions as approved. Continuously looks for new and better ways to deliver Clinical Development (CD) agenda. Prepares content for pivotal initiatives on behalf of the Head of Clinical Development/Head Portfolio Strategy & Operations. Support the streamlining and provide governance co-leadership for the Head Portfolio Strategy and Operations CD, ensuring consistent messaging across various governance forums (DevLT, CD LT). Support the build of the CD organization, creating and tracking meticulous and quantifiable objectives and communications; to support CD embedding best in class approaches to clinical development while growing deep therapeutic expertise. Lead on the benchmarking of CD activities at Novartis vs. peers Helps shape, influence and lead on functional strategy related activities and requests e.g., cross functional activities such as SRC governance with Global Medical Affairs, new initiatives to strengthen Development and CD, requests from Strategy Program Portfolio Operations. Represents the Head of Portfolio Strategy and Operations with cross-functional teams and within Clinical Development where needed. Supports the annual Clinical Development Strategy Review and objectives setting in collaboration with the CD Head, Clinical Development Heads and CD functional heads. Helps maintain updated CD program and above program reviews for, e.g., IMB, DevLT partnering closely with functional leaders. Ensure connectivity with global line functions to establish CD leadership amongst related functional teams, to ensure objectives are met, as mandated by DevLT/IMB. For example, work with Methods Head to establish IEP review process, work with Program Excellence & Capability Head to establish and embed Integrated Data Review, work with Data Design & Clinical Innovation head to help establish protocol AI. Supports the Head of Portfolio Strategy & Operations, to establish relationships and reinforce CD as single point leader for clinical programs, including Global Clinical Operations, Analytics, and Global Medical Affairs. Provides analytic insights into potential S&G, M&A and BD&L initiatives to evaluate from clinical perspective new opportunities Responsible for effective internal and external communication co-ordination on initiatives led by CD that warrant white papers or other external communication, e.g. updates to DevLT, IMB, Leadership forums. Navigates complexity and drives effectiveness across the function and in collaboration with other functions in Novartis Work closely with Head of Operational Excellence, Clinical Development Function Heads, head of Clinical Workforce Insights, Head of Capabilities, Engagement Lead. What you will bring to the role: Master degree or equivalent advanced degree or equivalent education/degree in life science/healthcare preferred (MD, PhD) ≥5 years people and matrix management required. Global people management experience desirable. Strong relationship builder and communicator with experience leading diverse work teams, driving program excellence, engaging functional partners Previous work and leadership in international and multidisciplinary drug development teams Strong knowledge of drug development strategy, Novartis experience in this area is preferred. Strong planning and project management skills Organizational awareness, including meaningful experience working cross-functionally and in global teams. Strong written & verbal communication coupled with excellent problem-solving, negotiation and conflict resolution skills. Strong communication skills with excellence understanding of presentation tools Experience in Consulting/Banking (Healthcare focus) preferred. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Senior Scientist - Genetically Engineered Models (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10004875 Apr 30, 2024 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite This role is a highly technical and a specialized professional position responsible for collaborating with multi-discipline research programs by providing high quality & consistent coordination of breeding activities in the field of genetically engineered models (GEM-s). About the Role Novartis' Biomedical Research division is our Innovation engine. We have bold objectives to transform the lives of millions of people living with diseases and conditions and unmet medical needs We currently have an opportunity for a Breeding Coordinator (Senior Scientist I) to join us and contribute in making a real impact to patient lives. This role is a highly technical and a specialized professional position responsible for collaborating with multi-discipline research programs by providing high quality & consistent coordination of breeding activities in the field of genetically engineered models (GEM-s). Your responsibilities will include: Ensure state-of-the-art coordination of GEM-s breeding activities with highest ethical and technical standards - -breeding for purpose- Plan, implement and track breeding activities for various types of GEM-s, from early-stage Animal Engineering projects to large production projects, both internally and at 3rd parties (CRO-s) Previous experience in Animal Engineering (e.g. in model design and genetic characterization of founder animals) would be advantageous Closely and independently interact with scientists, located at all global Novartis sites, to advise on and plan breeding strategies Closely interact with colleagues from the genotyping and embryology laboratories to ensure timely availability of genotyping data and to initiate cryopreservation and storage of GEM-s Responsible for pursuing continuous learning/professional development opportunities, enhancing/expanding skill set, and reviewing CM techniques and processes Conduct presentations of data and results to the GEM-s team and Novartis project teams Role Requirements : What you'll bring to the role: Bachelor or Master degree with a focus on genetics and with completed education as in-vivo laboratory technician (LTK 1 or equivalent), OR animal caretaker with profound experience in GEM-s breeding. (Please note that we do not require a PhD level candidate for this position at this time). Minimum 7 - 8 years of experience in a GEM-s breeding program required, experience in overseeing activities at CRO-s would be beneficial Good understanding of genetics and ability to plan complex breeding schemes involving GEM-s lines carrying multiple genetic modifications, as well as the corresponding project management expertise Superior written and oral communication and data documentation skills required Strong commitment to animal welfare, team player, detail-oriented Fluent in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture We offer plentiful benefits, state-of-the art facilities and helpful resources - all designed to help you thrive personally as well as professionally. You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No
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16.07.2024

Novartis AG

QC Analyst II.

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10014886 Jul 09, 2024 Switzerland Summary ~Unterstützt alle GxP-Aktivitäten in der Qualitätsabteilung. Verwaltet Qualitätssysteme / Prozesse einschließlich Dokumentation, Metriken und Überwachung von Aktionen. ~ Unterstützt die Etablierung von Qualitätsbetriebsprozessen. Führt routinemäßige GxP-Compliance/ Operative Aktivitäten gemäß den Novartis Qualitätsstandards durch. Unterstützt Qualitätsprojekte und -initiativen. About the Role Diese Stelle ist auf 2 Jahre ausgeschrieben. Ihr Verantwortungsbereich: Behält die geltenden Standard Operating Procedures (SOPs), GxP-konforme Dokumentationen und Aufzeichnungen innerhalb des Novartis Qualitätsmanagementsystems bei. Gewährleistet die Integrität aller Qualitätssicherungsdatensätze und -daten, soweit anwendbar, und die Zusammenarbeit des eigenen Teams mit anderen Funktionen und Abteilungen. Gewährleistet ein angemessenes Bildungsniveau, GxP-Kenntnisse. Aktualisierung und Verwaltung relevanter Informationen in elektronischen Systemen (z.B. Change Control, Dokumentation, Training). Weiterverfolgung und Überwachung von z. B. CAPAs, Maßnahmen, Metriken, Qualitätsplan). Unterstützt Qualitätsaudits und Inspektionen durch die Gesundheitsbehörde. Meldung von technischen Beschwerden / unerwünschten Ereignissen / Sonderfallszenarien im Zusammenhang mit Novartis-Produkten innerhalb von 24 Stunden nach Erhalt Verteilung von Vermarktungsmustern (falls zutreffend) Was Sie zur Rolle mitbringen: QC/ QA in der pharmazeutischen Industrie/Biotechnologie mit Umweltüberwachung und Reinheitszonen QA (Qualitätssicherung) und Qualitätskontrolle (Qc) Prüfung GMP-Verfahren Qualitätsmaßstäbe Technologisches Know-how und technologische Intelligenz Englische Sprache Warum Novartis? Über 766 Millionen! - so viele Leben haben wir im Jahr 2021 mit unseren Produkten erreicht. Und während wir darauf stolz sind, stellen wir uns ständig die Frage: Wie können wir in einer Welt des digitalen und technologischen Wandels noch mehr Leben verbessern und verlängern? Wir glauben, dass an der Schnittstelle von medizinischer Wissenschaft und digitaler Innovation neue Erkenntnisse, Perspektiven und bahnbrechende Lösungen gefunden werden können und dass ein vielfältiges, gleichberechtigtes und integratives Umfeld zu neuen Arbeitsweisen inspiriert. Wir sind davon überzeugt, dass unser Potenzial in einer von Integrität, Neugier und Flexibilität geprägten Kultur gedeihen und wachsen kann. Und wir können neu erfinden, was möglich ist, wenn wir mit Mut zusammenarbeiten, um die schwierigsten medizinischen Herausforderungen der Welt offensiv und ehrgeizig anzugehen. Denn das größte Risiko im Leben ist das Risiko, es nie zu versuchen! Stellen Sie sich vor, was Sie hier bei Novartis tun könnten! Engagement für Vielfalt & Inklusion Novartis ist bestrebt, ein hervorragendes, integratives Arbeitsumfeld und ein vielfältiges Team aufzubauen, das die Patienten und Gemeinschaften, denen wir dienen, repräsentiert. Zugänglichkeit und Unterbringung Der Novartis Konzern ist bestrebt, mit allen Personen zusammenzuarbeiten und ihnen angemessene Vorkehrungen zu bieten. Wenn Sie aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigen oder um detailliertere Informationen über die wesentlichen Funktionen einer Stelle zu erhalten, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihrer Anfrage und Ihre Kontaktdaten mit. Bitte geben Sie in Ihrer Nachricht die Nummer der Stellenausschreibung an. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber in Verbindung bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, werden Sie hier Mitglied des Novartis Netzwerks: https://talentnetwork.novartis.com/en\_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Befristet (Befristet) Shift Work No
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16.07.2024

Novartis AG

QC Analyst II.

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10014886 Jul 09, 2024 Switzerland Summary ~Unterstützt alle GxP-Aktivitäten in der Qualitätsabteilung. Verwaltet Qualitätssysteme / Prozesse einschließlich Dokumentation, Metriken und Überwachung von Aktionen. ~ Unterstützt die Etablierung von Qualitätsbetriebsprozessen. Führt routinemäßige GxP-Compliance/ Operative Aktivitäten gemäß den Novartis Qualitätsstandards durch. Unterstützt Qualitätsprojekte und -initiativen. About the Role Diese Stelle ist auf 2 Jahre ausgeschrieben. Ihr Verantwortungsbereich: • Behält die geltenden Standard Operating Procedures (SOPs), GxP-konforme Dokumentationen und Aufzeichnungen innerhalb des Novartis Qualitätsmanagementsystems bei. • Gewährleistet die Integrität aller Qualitätssicherungsdatensätze und -daten, soweit anwendbar, und die Zusammenarbeit des eigenen Teams mit anderen Funktionen und Abteilungen. • Gewährleistet ein angemessenes Bildungsniveau, GxP-Kenntnisse. • Aktualisierung und Verwaltung relevanter Informationen in elektronischen Systemen (z.B. Change Control, Dokumentation, Training). • Weiterverfolgung und Überwachung von z. B. CAPAs, Maßnahmen, Metriken, Qualitätsplan). • Unterstützt Qualitätsaudits und Inspektionen durch die Gesundheitsbehörde. • Meldung von technischen Beschwerden / unerwünschten Ereignissen / Sonderfallszenarien im Zusammenhang mit Novartis-Produkten innerhalb von 24 Stunden nach Erhalt • Verteilung von Vermarktungsmustern (falls zutreffend) Was Sie zur Rolle mitbringen: • QC/ QA in der pharmazeutischen Industrie/Biotechnologie mit Umweltüberwachung und Reinheitszonen • QA (Qualitätssicherung) und Qualitätskontrolle (Qc) Prüfung • GMP-Verfahren • Qualitätsmaßstäbe • Technologisches Know-how und technologische Intelligenz • Englische Sprache Warum Novartis? Über 766 Millionen! - so viele Leben haben wir im Jahr 2021 mit unseren Produkten erreicht. Und während wir darauf stolz sind, stellen wir uns ständig die Frage: Wie können wir in einer Welt des digitalen und technologischen Wandels noch mehr Leben verbessern und verlängern? Wir glauben, dass an der Schnittstelle von medizinischer Wissenschaft und digitaler Innovation neue Erkenntnisse, Perspektiven und bahnbrechende Lösungen gefunden werden können und dass ein vielfältiges, gleichberechtigtes und integratives Umfeld zu neuen Arbeitsweisen inspiriert. Wir sind davon überzeugt, dass unser Potenzial in einer von Integrität, Neugier und Flexibilität geprägten Kultur gedeihen und wachsen kann. Und wir können neu erfinden, was möglich ist, wenn wir mit Mut zusammenarbeiten, um die schwierigsten medizinischen Herausforderungen der Welt offensiv und ehrgeizig anzugehen. Denn das größte Risiko im Leben ist das Risiko, es nie zu versuchen! Stellen Sie sich vor, was Sie hier bei Novartis tun könnten! Engagement für Vielfalt & Inklusion Novartis ist bestrebt, ein hervorragendes, integratives Arbeitsumfeld und ein vielfältiges Team aufzubauen, das die Patienten und Gemeinschaften, denen wir dienen, repräsentiert. Zugänglichkeit und Unterbringung Der Novartis Konzern ist bestrebt, mit allen Personen zusammenzuarbeiten und ihnen angemessene Vorkehrungen zu bieten. Wenn Sie aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigen oder um detailliertere Informationen über die wesentlichen Funktionen einer Stelle zu erhalten, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihrer Anfrage und Ihre Kontaktdaten mit. Bitte geben Sie in Ihrer Nachricht die Nummer der Stellenausschreibung an. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber in Verbindung bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, werden Sie hier Mitglied des Novartis Netzwerks: https://talentnetwork.novartis.com/en_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Befristet (Befristet) Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Principal Scientist - Radioligand Therapy (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10010495 Jun 11, 2024 Switzerland Summary Novartis' Biomedical Research division is our Innovation engine. Within our ground-breaking Radioligand Therapy Labs in our Oncology division we have ambitions to transform the lives of millions of people living with cancer and focus in powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Oncology Research department at Novartis Institutes for Biomedical Research is recruiting for a Ph.D. level Principal Scientist with a strong background and track record in cancer cell biology. Expertise in the field of radioligand therapy development and/or radiobiology would be desirable. About the Role The candidate will join an Oncology Drug Discovery Research group located in Basel/Switzerland and will be responsible to lead projects in the areas of oncology drug discovery and radioisotope-based therapies. This is an excellent opportunity to join a world class research team at NIBR in Basel, Switzerland. The successful candidate exhibits strong leadership skills, a collaborative team spirit, excellent communication skills and willingness to pro-actively interact across the global organization. Excellent mentoring and coaching skills will be a necessary asset to develop team members scientifically and professionally. Your responsibilities will include: · Design and manage in vivo studies to support the preclinical evaluation of novel radioligand therapies (efficacy, biodistribution, PET/SPECT imaging and MoA studies) · Collaborate with cross-functional project teams (chemistry, clinical, safety, pathology etc) to advance novel radioligand therapies to the clinic. · Work effectively with CROs and academic institutes. · Guide, supervise and develop team members across functions. · Present concepts and projects in a clear, scientifically sound and data-driven, objective manner in different settings and venues. · Work closely with multiple teams across expertise groups within Oncology and across departments in the global organization (e.g. BD&L, Global Drug Development, Commercial). What will you bring to the role: Ph.D. in pharmacology and/or cell biology with a minimum of 3 years additional experience in biomedical research (either industry or academia). Strong background in cancer biology and a track record of scientific accomplishment at high standards. Considerable experience performing and managing in vivo oncology studies (efficacy, PK/PD, ex vivo analysis by flow cytometry, IF/IHC, RNA Seq etc). Highly collaborative team player that enjoys working across multi-disciplinary team. Background in radioligand therapy development/radiobiology is highly desirable - Strong experience in drug development would be favorable. Excellent communication and presentation skills in English. Self-motivated, proactive, and able to work independently. * This position is eligible for 80-100%* working time, however, some restrictions on flexible working options may apply and will be discussed during interview if applicable. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

Principal Scientist I - Toxicology (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10009448 Jun 04, 2024 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking to hire a motivated candidate with a strong background in cellular and molecular immunology to join our Translational Immunology Unit in Basel within our Biomedical Research division. This is a unique opportunity to apply your deep knowledge of immunology to enable state-of-the-art cross-species immune system safety assessments for novel life-saving medicines during early and late phases of development. In collaboration with preclinical and clinical teams as well as external academic partners, you will lead innovative in vivo and in vitro experimental approaches to assess hazards and risks for drug-induced immunopathology and immune-mediated toxicity. Your contributions will enhance and accelerate the drug discovery and development portfolio of Novartis, bringing forward effective and safe medicines. About the Role Your responsibilities include, but are not limited to: Contribute and perform relevant experimental methods and scientific judgement to cross-species immune safety assessments introducing, developing, implementing, validating, and maintaining state-of-the-art technologies and laboratory procedures. Perform target reviews and translational immune system safety assessments for early and late development projects. Interface with internal clinical and preclinical teams and manage external academic collaborations. Interface with regulatory agencies. Present scientific/technical work and achievements at internal / external meetings. Publish results in internal repositories, in peer reviewed journals and as patent applications, as appropriate. Minimum requirements: Education: MD/DVM and/or PhD with strong experience (3-5 years) in immunology and infection diseases biology. Extensive experimental immunology with a strong research profile in both human and preclinical species. Good understanding of drug-induced immune reactions. Excellent communication skills and fluency in oral and written English. Knowledge of the scientific disciplines involved in drug safety assessment, including relevant laboratory procedures related to safety risk management, as well as experience with large data analysis will be advantageous. Proficiency with major state-of-the-art immunology technologies and approaches. Proven expertise in scientific and technical problem-solving, ideally within an international, multi-disciplinary environment. Proven experience supervising scientists, leading projects and working cross-teams. Desirable requirements: Excellent scientific publication record. Good scientific network with academic institutions. Proven program and project management skills and conflict solving abilities in matrix environments. *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No
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16.07.2024

Novartis AG

Principal Scientist II Drug Discovery - Kidney Diseases (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10006954 May 15, 2024 Switzerland Summary Location: Basel, Switzerland or Cambridge Mass, US Full time, onsite, #LI-onsite We are seeking an innovative and dynamic scientist with broad expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease. In this role, you will be responsible for driving research programs focused on delineating the key mechanisms involved in proteinuric kidney diseases and progressing new targets towards drug discovery. This individual will join the Renal Research team within Disease Area X (DAx) in Biomedical Research and report to the Head of Renal Research. About the Role Major accountabilities: Contribute to the Biomedical Research drug discovery process with the goal of progressing the development of new therapeutic options for patients with chronic kidney diseases. Formulate novel target hypothesis based on human disease mechanisms using deep and broad scientific expertise in renal physiology and pathophysiology of proteinuric kidney diseases. Design and execute in vitro and in vivo research plans to deliver high quality data-driven package and enable project decisions. Deliver impact to projects by identifying technical trends, both internal and external to your discipline. Lead multi-disciplinary project team(s) to portfolio transitions a/o decision milestones. Enable partnerships with data scientists, external partners, and individuals across Biomedical Research Disease Areas and platform functions. Develop and communicate project strategy, scientific vision, and data to key stakeholders. Manage and develop a team of research scientists. Develop and maintain external relationships/contacts. Essential requirements: A PhD and/or MD degree with postdoctoral experience and a minimum of three years of research in renal biology and physiology, preferably in the pharmaceutical or biotechnology industry. In-depth knowledge of kidney (patho-)physiology, including cultivation and analysis of complex renal cell-based platforms, e.g. 3D kidney organoids, primary 2D/3D endothelial or epithelial cell systems. Extensive -hands-on- experience and proven track-record in the use of a wide range of cellular, biochemical and genome editing methods and technologies to unravel complex cellular signaling pathways. Proficiency in -state of the art- computational and analytical approaches and comfortable with analyzing large scale genetic, NGS and single cell datasets. A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases. Ability to lead a project and plan ahead, be well organized and effectively use resources to execute experiments and deliver high quality data in a timely fashion. A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts. Experience in leading and mentoring associates and cross-functional teams. Excellent oral and written communication skills (in English) are essential. *Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

Principal Scientist - Drug Discovery Glomerulonephritis (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID 390562BR Jun 11, 2024 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Immunology (IMM) department is accommodated within the Biomedical Research department of Novartis and works in collaboration with colleagues from Novartis Research and Development on several therapeutic areas with high unmet need, including autoimmune and inflammatory kidney diseases. Using a diverse array of approaches and ground breaking technology, IMM strives to develop drugs that improve the lives of individuals suffering from autoimmune and inflammatory kidney diseases for which there is currently no cure. At Novartis we have a bold ambition to transform the lives of millions of people living with such diseases. About the Role We are seeking an innovative, independent and dynamic Principal Scientist with broad expertise in nephrology and immunology to join a discovery biology team focused on developing innovative therapeutic agents in the area of glomerulonephritis. Your responsibilities will include: Contribute to the Biomedical Research drug discovery process with the goal to discover and develop novel therapeutic treatment options for patients with glomerulonephritis. Lead drug discovery projects in the renal disease space, propose and champion new targets and novel approaches for disease treatment. Contribute to translational research activities and mechanism of action studies to support ongoing clinical development programs Design and execute in vitro and in vivo research plans to evaluate targets modulating glomerulonephritis indications. Engage in interdisciplinary research requiring the application of specialized scientific knowledge and advanced laboratory techniques, in particular in vitro and in vivo models of glomerular diseases. Collaborate with other scientists in a global matrixed dynamic environment fostering innovation and advance project activities. Develop and maintain external relationships/contacts. What you will bring to the role: A PhD and/or MD degree with Postdoctoral experience and a minimum of three years of research in renal biology and/or immunology, preferably in the pharmaceutical / biotechnology industry or academia. In-depth knowledge of pathophysiology of autoimmune and inflammatory glomerular diseases, especially around the role of pathogenic autoantibodies in disease i.e. expert in B cell biology, immune complex mediated renal diseases, autoantibody mediated effector function and inflammatory pathways in renal diseases. A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases. A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts. Excellent oral and written English communication skills, with an ability to effectively interact with people in a dynamic matrix environment, both internally and externally Experience in leading and mentoring associates and cross-functional teams *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

In vivo DMPK expert - Principal Scientist PK Sciences (PKS)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10010396 Jun 19, 2024 Switzerland Summary 6000! That-s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. About the Role Your responsibilities include, but are not limited to: Plan, design, monitor, and report in vivo ADME, pharmacokinetic (PK) and PK/PD studies in rodents and non-rodents, in order to support preclinical projects across Novartis Biomedical Research portfolio. Discuss study rational, and manage timelines, and resources. Evaluate and interpret results, draw relevant conclusions, write or review reports. Ensures accuracy of study data within corporate databases and project tracking tools. Communicate study results and data interpretations to cross-functional project teams. When these studies are outsourced at External Service Providers (ESP), drive and monitor study preparations, execution and reporting in collaboration with ESPs. Independently recognize challenges and hurdles (operational, technical, or scientific) and provide relevant input or proposal for solution/problem solving. Actively participate in PKS project sub-teams to define PK strategy for compound progression and development and contribute to relevant transition documents such as investigator brochures within agreed timelines and with all regulatory requirements. Be a pro-active, innovative, and solution-oriented team player, which actively contributes to development and refinements of new in vivo PK/ADME methods and technologies. Having scientific knowledge and expertise on new drug modalities and delivery technologies can be an advantage. Comply with Swiss and Novartis-specific rules and regulations, e.g., Animal Welfare regulations, 3R principles, Novartis quality standards. Overall, excellent collaboration, coordination and communication skills with other scientists within the team, within our matrix organization and with ESPs are mandatory. Fostering an atmosphere of mutual respect is key. Depending on the level of expertise, train and actively mentor junior members of team. *Some restrictions on flexible working options will apply and will be discussed during interview if applicable. Commitment to Diversity & Inclusion: : We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role requirements: What you-ll bring to the role: Masters degree or PhD in biology or related sciences with 3-5 years of working experience, preferably in the area of DMPK in pharmaceutical, biotechnology industry, or ESPs. Good understanding of the pharmacokinetic science, the drug discovery and development phases, as well as a general awareness of the outsourcing operational excellence. Good understanding and knowledge of in vivo techniques, instrumentation, and underlying principles within in vivo ADME/PK field. Experience in rodent experimentation and in large animal PK and PKPD studies are considered as beneficial (animal handling, drug application, sampling). Competency and interest in working with different IT systems and advanced computer literacy, on a daily basis (MS Office, Sharepoint, Phoenix WinNonlin, Internal databases, etc.). Curious mindset, with high interest to continuously learn, develop, implement and/or optimize new or existing experimental methods. Team player with excellent communication and a collaborative mindset. Excellent oral and written communication skills in English is a must; some knowledge of German considered beneficial. Why consider Novartis? 750 million. That-s how many lives our products touch. And while we-re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people-s lives? We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you-re given opportunities to explore the power of digital and data. Where you-re empowered to risk failure by taking smart risks, and where you-re surrounded by people who share your determination to tackle the world-s toughest medical challenges. We are Novartis. Join us and help us reimagine medicine. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

Ground Services Manager

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10011036 Jun 21, 2024 Switzerland Summary Location: Basel, Switzerland #LI-Hybrid The Ground Services Manager plays a critical role in the efficient and effective operation of ground services for JAPAT, so this role requires a strong aviation background, extensive leadership experience, and a service-oriented mindset. Reporting directly to the Accountable Manager (AM), the Ground Services Manager is responsible for leading the ground operations team and ensuring seamless coordination between ground operations and all other processes involved in the JAPAT flight activities. About the Role Key Responsibilities: Team Leadership: Lead, mentor, and develop the ground operations team, fostering a positive culture of accountability, teamwork and continuous improvement. Provide guidance and support to the team members, ensuring they have the required resources and learning, training and development opportunities to perform their roles effectively. Foster a positive team culture by effective communication, empowerment of all team members to work independently and efficiently, recognizing and valuing their contributions and identify and resolve conflicts before they aggravate. Stakeholder Management: Serve as the primary point of contact for the Novartis booking agents, providing personalized assistance and ensuring their needs are met before and after flights. Maintain strong communication channels with all JAPAT internal stakeholders to coordinate ground services and address any operational issues or concerns. Cooperation with the Nominated Person Flight Operations (NPFO) to liaise on all processes between both entities as well as with the Nominated Person Safety and Compliance (NPSC) for all safety related matters and to address non compliances and/or root cause analysis (CAPAs). Vendor Coordination: Liaise with ground support vendors, including Fixed Base Operators (FBOs), fueling companies, and deicing providers, to ensure timely and efficient service delivery. Pre-flight and Post-flight Operations: Oversee the JAPAT pre-flight and post-flight processes, to ensure a smooth and enjoyable travel experience for passengers and follow up on all service-related deviations (in close collaboration with the NPFO and the Cabin Attendant Manager). Process Improvement: Identify opportunities for process improvement and implement strategies to enhance the efficiency and effectiveness of ground service operations as well as develop and monitor metrics to measure the performance of ground services and identify areas for improvement. Essential Requirements: Bachelor's degree in Aviation Management, Business Administration, or a related field Experience in aviation operations, with a strong understanding of ground handling procedures and regulations as well as aviation safety regulations and best practices Proven leadership experience, with the ability to effectively lead and develop a team of aviation professionals Excellent communication skills and ability to interact professionally with internal and external stakeholders at all levels Strong service mindset, with a focus on delivering exceptional customer service and ensuring passenger satisfaction paired with a can-do-attitude and effective problem-solving skills Proficiency in Microsoft Office suite and aviation-specific software systems Flexibility to work irregular hours, including evenings, weekends (as needed) and willingness to travel occasionally for training and professional development opportunities Proficiency in English (written and spoken), knowledge of German is a plus Desirable Requirements: Business aviation and flight dispatch background Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. Thrive Together (novartis.com) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Corporate Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Global Head of Data Engineering - Advanced Methodology and Data Science

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%FührungspositionManagement / Kader

Festanstellung 100%

FührungspositionManagement / Kader

Basel

Job ID REQ-10011660 Jul 04, 2024 Switzerland Summary Global Head of Data Engineering - Advanced Methodology and Data Science Location: Basel, Switzerland; London, UK About the Role: The Global Head of Data Engineering - Advanced Methodology and Data Science will be responsible for world-class technical and organizational leadership in the area of data engineering, unlocking the analytical potential of complex data sources and AI to produce evidence and support decisions in drug development. This position will have critical business impact for data engineering across Novartis Drug Development and scalable data pools can support Biomedical Research and pave the way for statistical programming modernization with regard to GxP reporting activities. About the Role Key Responsibilities : Promote cutting-edge efficient data engineering and data wrangling for priority pools to support in-depth data interrogation at the project and trial level for priority programs Be the Analytics technical lead with the data asset owner from Analytics DU team in order to plan, create and maintain data products in an efficient and scalable manner Support cross-functional teams in utilizing these data assets from Biomedical Research through Biomarker Development, Precision medicine through Development and medical affairs, and work with internal & external data engineering experts to grow capabilities and infrastructure in a reusable and scalable way. Bridge data and knowledge engineering together with more traditional statistical programming skills, to bring automation and modern processes to reporting activities for trials and programs: Establish data engineering as a process and function that is an essential capability to leverage complex (multi-modal and/or pooled) datasets to generate evidence that can support HA interactions / submission work and in-depth data interrogation. Establish data engineering practices that ensure automated testing with documented code-review and have automated, reproducible QC reports accompany all data releases. Engage as a key contributor to the AMDS (Advanced Methodology and Data Science) Leadership team, propose, lead or contribute to functional or cross-functional data engineering initiatives, coordinating diverse team members to support priority projects across Analytics, Statistical Methods and AEA (Advanced Exploratory Analytics) teams in AMDS. Attract and develop strong talent to a team that can deploy a range of data and software engineering skills alongside data science and AI in order to support data engineering activities across the broader Analytics group and extend to Biomedical Research. Bring data and software engineering mindset and deep technical expertise to the technology infrastructure projects, the wider organization and the pharma community: Essential Requirements: Deep knowledge and 10+ years of experience in global drug development, including data pooling strategy, technology and computing environments, AI and modernization Proven expertise in quantitative sciences, including good data science practices, working with and engineering multi-modal large data, strategic input to technology platforms Experience working in a fast-paced environment with multiple competing priorities proven ability to operate in a matrixed environment, with a high tolerance for ambiguity and change Excellent presentation and communication skills, influencing and senior stakeholder management skills and collaboration Thorough knowledge of GxP, IT systems, QA and regulatory/clinical development process Ability to represent the organization in senior internal and external forums Fluency in English, written and oral Benefits and rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Global Head of Data Engineering - Advanced Methodology and Data Science

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%FührungspositionManagement / Kader

Festanstellung 100%

FührungspositionManagement / Kader

Basel

Job ID REQ-10011660 Jul 04, 2024 Switzerland Summary Global Head of Data Engineering - Advanced Methodology and Data Science Location: Basel, Switzerland; London, UK About the Role: The Global Head of Data Engineering - Advanced Methodology and Data Science will be responsible for world-class technical and organizational leadership in the area of data engineering, unlocking the analytical potential of complex data sources and AI to produce evidence and support decisions in drug development. This position will have critical business impact for data engineering across Novartis Drug Development and scalable data pools can support Biomedical Research and pave the way for statistical programming modernization with regard to GxP reporting activities. About the Role Key Responsibilities : Promote cutting-edge efficient data engineering and data wrangling for priority pools to support in-depth data interrogation at the project and trial level for priority programs Be the Analytics technical lead with the data asset owner from Analytics DU team in order to plan, create and maintain data products in an efficient and scalable manner Support cross-functional teams in utilizing these data assets from Biomedical Research through Biomarker Development, Precision medicine through Development and medical affairs, and work with internal & external data engineering experts to grow capabilities and infrastructure in a reusable and scalable way. Bridge data and knowledge engineering together with more traditional statistical programming skills, to bring automation and modern processes to reporting activities for trials and programs: Establish data engineering as a process and function that is an essential capability to leverage complex (multi-modal and/or pooled) datasets to generate evidence that can support HA interactions / submission work and in-depth data interrogation. Establish data engineering practices that ensure automated testing with documented code-review and have automated, reproducible QC reports accompany all data releases. Engage as a key contributor to the AMDS (Advanced Methodology and Data Science) Leadership team, propose, lead or contribute to functional or cross-functional data engineering initiatives, coordinating diverse team members to support priority projects across Analytics, Statistical Methods and AEA (Advanced Exploratory Analytics) teams in AMDS. Attract and develop strong talent to a team that can deploy a range of data and software engineering skills alongside data science and AI in order to support data engineering activities across the broader Analytics group and extend to Biomedical Research. Bring data and software engineering mindset and deep technical expertise to the technology infrastructure projects, the wider organization and the pharma community: Essential Requirements: Deep knowledge and 10+ years of experience in global drug development, including data pooling strategy, technology and computing environments, AI and modernization Proven expertise in quantitative sciences, including good data science practices, working with and engineering multi-modal large data, strategic input to technology platforms Experience working in a fast-paced environment with multiple competing priorities proven ability to operate in a matrixed environment, with a high tolerance for ambiguity and change Excellent presentation and communication skills, influencing and senior stakeholder management skills and collaboration Thorough knowledge of GxP, IT systems, QA and regulatory/clinical development process Ability to represent the organization in senior internal and external forums Fluency in English, written and oral Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Drug Product Project Leader - Parenterals (m/f/d)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013083 Jul 08, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Join our team in Pharmaceutical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical experience. Demonstrated expertise in formulation development (parenteral, aseptic, solution, and/or suspension) and manufacturing process development Experience with aseptic Drug Product manufacturing of parenterals, including process transfer, scale-up and QbD design. Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Knowledge of regulatory requirements in parenteral Drug Product development and manufacturing is a plus. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Drug Product Project Leader - Parenterals (m/f/d)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013083 Jul 09, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Join our team in Pharmaceutical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Data Science Innovation Fellow, Structural Bioinformatics

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10010397 Jun 10, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in computational and data science, AI/ML methodology, protein science, high throughput screening as well as modeling/computer-aided drug design, you will leverage state-of-the-art AI methodology and unique internal datasets to model protein-protein and protein-ligand interactions and drive drug discovery efforts. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage large, proprietary data sets to fine-tune innovative AI models for protein-ligand structure predictions. Design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Collaborate with cross-functional teams and apply the latest structural AI models to real world drug discovery projects. Explore the application of the latest structure-based AI methods to drug discovery workflows and present your findings to the scientific community at BR (Biomedical Research) Role requirements : PhD in computational biology, cheminformatics, structural biology or equivalent, with extensive computational experience (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to protein modeling, drug discovery or small molecule design. Strong background in structural AI methods (e.g., Alphafold, Rosetta Fold, Openfold). Proficiency in Python and machine learning libraries (e.g., TensorFlow, PyTorch, Jax) in high performance computing/cloud computing environments (e.g. AWS). Experience with protein-ligand interaction prediction and drug discovery workflows. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 15 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow - Renal Translational Research

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012381 Jun 19, 2024 Switzerland Summary You are encouraged to apply for our Data Science Innovation Fellowship, which is a three-year post-doctoral research program to augment the way we approach drug discovery. The fellow will have the unique opportunity to train in data science and AI for biomedical research. As a fellow, you will apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will participate on a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying innovative data approaches in collaboration with a vibrant community of over 300 data scientists globally. The program provides a unique platform to access real-world, biomedical data at scale, rarely available in academia. Working with experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with options for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Your project will evolve practices in disease target identification and drug discovery through strengthening our ability to translate mechanistic insights gained from preclinical models to human kidney diseases. Developing a more sophisticated understanding of drug-kidney interactions is a crucial step towards creating successful drugs. To this end, you will use your quantitative background and leverage large-scale data to derive mechanistic insights from preclinical models relevant to human kidney biology and pathophysiology. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Advance methods and practices in spatial transcriptomics, including integrated histology image and transcriptomics analysis at scale. Explore novel multimodal and transfer learning analysis approaches towards advances in translatable kidney function assessment. Leverage a knowledgebase of hundreds of rodent studies to characterize the range of notable observations made on preclinical and patient kidney data. Uncover and seize opportunities for drug development by identifying relationships in large-scale datasets that can guide preclinical safety evaluations and novel target hypotheses. Collaborate closely with colleagues in toxicology, pathology, early discovery, and data sciences. Foster the role of data science and AI in drug discovery by implementing best practices and making data more accessible. Communicate research results to both internal and external audiences, such as scientific conferences and publications. Role requirements : PhD in a quantitative field (data science, machine learning, computer science, statistics) or life sciences, preferably with multidisciplinary background (chemoinformatics, bioinformatics, biomedical engineering, AI/ML in drug discovery or life sciences). PhD students in the last year of their thesis work, are eligible to apply. Solid understanding of statistics, machine learning and deep learning; Demonstrated knowledge of data visualization and exploratory analysis. Knowledge of Python and/or R, as well as machine learning/deep learning libraries. Experience with generative algorithms and explainable AI is a plus. Experience with reproducible data science tools and practices. Strong publication record or other scientific achievements (i.e. awards, patents, grants, public code repository) Highly effective analytical, communication, presentation, and organizational skills Passion for research and boundless curiosity. Team player. Strives for continuous learning (scientific and technical). #DSIF How to apply Please submit your CV and cover letter by July 15 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow, Multimodal Neuroscience

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013277 Jun 26, 2024 Switzerland Summary 275 million years of life were prematurely lost due to neurological conditions in 2021. We are now looking for a Data Science Innovation Fellow to join us in our mission to develop disease-modifying treatments for some of the most common, debilitating neurodegenerative diseases. Leveraging rich real-world data from patients, you will develop cutting-edge multimodal approaches to investigate neurodegenerative disease progression and work together with our drug discovery teams to incorporate data science insights into our programs. This applied 3-year Data Science Innovation Fellowship program is set to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in data science and AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data Science and AI and shape the future of drug discovery! Start date: Autumn 2024 About the Role Location: Basel #LI Hybrid About the role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage your curiosity and creativity to investigate complex biological problems in drug discovery of neurodegenerative disease. Design computational workflows to integrate real-world data from patients with molecular readouts. Apply cutting-edge multimodal AI approaches across multiple data modalities, incl. clinical data, imaging, genetics, omics-, metabolomics. Empower our teams by collaborating with interdisciplinary groups, presenting findings, and communicating complex concepts to stakeholders. Role requirements PhD in a statistical or quantitative field such as computer science, data science, computational biology, mathematics, statistics, or physics, or a related field (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying machine learning to biomedical or biological problems, and experience in data manipulation, cleaning, and preprocessing techniques. Experience working with multiple data modalities or omics data (genomics, proteomics, transcriptomics, etc.) is a plus. Strong understanding of statistical analysis, mathematical modeling, and machine learning algorithms. Proficiency in Python, R with experience in frameworks and libraries commonly used in machine learning and AI, such as TensorFlow, PyTorch. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow - Histopathology Foundation Models

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013211 Jun 26, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Over the period of three years, you will conceptualize and develop general-purpose Histopathology Foundation Models by leveraging thousands of whole-slide histopathology images from our internal data archives. You will be deeply embedded in our Computational Pathology and Artificial Intelligence & Computational Science teams and will work on large-scale representation learning approaches to build models that will lay the foundation of AI-enhanced pathology-based applications within Novartis. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Implement the state-of-the-art and design custom self- and weakly-supervised algorithms to build Foundation Models for histopathology data. Work as a team member on AI research projects independently, focusing on large-scale imaging data and practicing scientifically rigorous and reproducible methodology. Collaborate with other AI specialists, data architects, software engineers and pathologists within Biomedical Research on applications in the histopathology domain. Engage with diverse stakeholders in non-clinical as well as clinical settings. Build a bridge between academia and industry partners. Keep ahead of the latest developments in the field and bring curious and critical thinking to the team. Role requirements : PhD in Computer Science, Machine Learning, or a related field with a focus on image and vision applications (PhD students in the last year of their thesis work, are eligible to apply). Strong programming experience in python and proficiency in at least one main deep learning framework (PyTorch/TensorFlow/JAX). Proven experience in implementing state-of-the-art machine/deep learning algorithms. Scientific publications in AI/ML conferences and/or in journals with a focus on computational biology/medicine. Ability to clearly communicate technical concepts to a variety of audiences, including scientists, engineers, and subject matter experts from other domains. Familiarity with working on high-performance computing systems and/or cloud computing environments and version controlling is nice to have. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Clinical Development Medical Director - Oncology

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10003632 Jul 08, 2024 Switzerland Summary -Leads the strategic and operational planning and management of the assigned clinical program(s) from an end-to-end clinical operations perspective. Complete oversight of budget and resource allocation for the assigned programs. Drives operational excellence through process improvement and knowledge sharing across the function. Enables an empowered organization which can navigate in a matrix environment and adjust quickly to business needs. About the Role Novartis is deeply committed to transforming the lives of people living with solid tumors. We believe that anyone living with these conditions has the right to a life free from pain, free from symptoms and free from disease - this is our vision for the future. Our mission is to reimagine medicine to extend and improve peoples lives - and our overall company strategy to achieve this is to Focus Novartis as a leading medicine company powered by data science and advanced therapy platforms such as Radioligand Therapy (RLT). Novartis has become the industry leader in RLT after the acquisition of Advanced Accelerator Applications (AAA) and Endocyte in 2018, together with other significant investments to advance radioligand research. Novartis Oncology is now developing a wide range of targeted RLTs, and precision Radioligand Imaging (RLI) agents, for oncology with a rich pipeline targeting multiple tumor types through a phenotypic precision medicine approach. Nuclear Medicine (NM) expertise is key for Novartis Oncology to expand RLT and supportive RLI agents in a sustainable manner. The Clinical Development Medical Director (CDMD) is responsible for leading the planning and management of the assigned RLI clinical program(s) to support the RTL trials from an end-to-end clinical development perspective. As CDMD, you will have oversight of assigned programs and drive execution of the plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. Your responsibilities as a Nuclear Medicine expert will include: Providing clinical leadership and strategic medical input for all clinical results in the assigned project or section of a clinical program Leading development of RLI related clinical sections of trial and program level regulatory documents Driving execution of the program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a Nuclear Medicine physician specialist, supporting the (Sr.) GPCH or CDH in interactions with external and internal partners and decision boards Contribute to the publication strategy of RLI/RLT compounds from the scientific standpoint May work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Commitment to Diversity & Inclusion: : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements : What you'll bring to the role: Nuclear medicine Physician/Medical Doctor Sophisticated knowledge and clinical training in oncology PET; Clinical practice experience - 5 years preferred. Experience in Clinical Trials with a PET component Experience with Radioligand therapy A consistent track record to interpret, discuss and present data relating to clinical trial(s) with a Nuclear Medicine component Demonstrated ability to establish effective scientific partnerships with key partners Solid understanding of GCP, clinical trial design, statistics, regulatory and clinical development processes Some restrictions to flexible working models may apply and will be discussed at interview if applicable Why consider Novartis? 769 million lives were touched by Novartis medicines in 2023, and while we-re proud of this, we know there is so much more we could do to help improve and extend people-s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world-s toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 India Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Clinical Development Medical Director - Immunology

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10008803 Jul 10, 2024 Switzerland Summary As the Clinical Development Medical Director (CDMD) Immunology you will lead clinical teams dedicated to autoimmune rheumatic disease development programs in indications of lupus, including both systemic lupus erythematosus and lupus nephritis, through all study phases from inception/design to database lock and read-out. Core responsibilities include planning and management of the assigned clinical projects(s) from an end-to-end clinical development perspective. Together with your team, you will drive execution of the clinical development plan. You will harness the strengths of a diverse team and create a collaborative and inclusive work environment You are eager to empower your team members, in a complex matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Lead development of clinical sections of trial and program level regulatory documents Drive execution of the program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors, and regional/country medical associates Support the Global Program Clinical Head in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety colleagues Support the Clinical Development Head by providing medical input into the Clinical Development Plan, Integrated Development Plan and Clinical Trial Protocol reviews. and contributing to development of disease clinical standards for new disease areas As a medical specialist, supporting the GPCH or CDH in interactions with external and internal partners and decision boards May work with Novartis Biomedical Research/ Translational Medical Sciences to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with other medical matters, as needed Key performance indicators: Timely, efficient and quality execution of trials and trial related activities within assigned clinical program(s) within budget, and in compliance with quality standards Appropriate funding and resourcing for assigned clinical program(s) Adherence to Novartis policy and guidelines and external regulations Minimum Requirements: MD or equivalent medical degree is required, in addition to a proven track record of clinical experience in and scientific contributions to your field of expertise Training or working experience in one or more of the following: 1) rheumatology or clinical immunology; 2) lupus clinical trials (systemic lupus erythematous and/or lupus nephritis; 3) B cell-depleting biologics 3+ years minimum in clinical research or drug development in immunology/inflammation Working knowledge in the area of Immunology and Inflammation with ability to interpret, discuss and present efficacy (clinical, biomarker) and safety data relating to clinical trials Understanding of GCP, clinical trial design, statistics, and regulatory and clinical development processes. Availability of, and readiness to leverage scientific and clinical networks to establish scientific partnerships with key collaborators Ability to confidently lead independent data monitoring committees and phase 2b/3 advisory boards Skills: Budget Management Clinical Research Clinical Trials Coaching Cross-Functional Teams Lifesciences People Management Risk Management Risk Monitoring Languages : English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Alternative Location 3 Spain Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Associate Director (m/f/d) Method Expert Team (80-100%)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%Management / Kader

Festanstellung 80-100%

Management / Kader

Basel

Job ID REQ-10008316 Jun 05, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Are you passioned to lead a team of Method Development Experts? Have you successfully developed analytical methods based on QbD Principles? Have you used automation solutions for method development? Do you thrive on challenges and enjoy creating new physicochemical methods for biopharmaceutical molecules? Would you be willing to develop and support your team associates in their professional growth? Are you attracted to living in a vibrant region of Europe with abundant cultural and outdoor activities? If you answered "yes" to all of these questions, then we want you to join the Novartis Process Analytical Sciences team in Basel, Switzerland. Our team develops Biologics drug substance and drug products, from candidate selection to launch, emphasizing agility, innovation, and scalability to best serve our portfolio, partners, and patients. About the Role Your key responsibilities As Associate Director you will lead the Method Expert Team of Process Analytical Sciences at our TRD Biologics site in Basel. Your responsibilities include, but are not limited to: Operational manager for approx. 7+ associates in total Collaboration and Leadership : As a team lead, you will be responsible for providing technical and scientific guidance but also to inspire your team. You will work with global cross-functional teams and manage interfaces e.g. with research, process development, quality assurance, scientific office, and regulatory affairs, e.g. to ensure alignment on method development or Process Analytical Technology (PAT) strategies. Method Development and Optimization using Quality-by-Design (QbD) Principles : Drive the physicochemical analytical (PCA) method development and optimization of assigned pipeline projects for all relevant sample matrices (Drug Substance, Drug Product, Intermediates). Provide guidance on experimental designs, risk assessments, and the use of statistical tools to ensure the development of robust and reliable analytical methods. Drive innovation programs: Advanced Instrumentation and Technology : Leverage advanced analytical instrumentation and emerging technologies to enhance existing analytical methods. Miniaturization and Automation : Explore opportunities for miniaturization and automation to increase throughput, reduce sample and reagent consumption, and enhance efficiency. Data-Driven Approaches : Utilize data analytics, machine learning, and artificial intelligence to analyze large datasets and develop data-driven approaches for method development. Identify critical quality attributes, process parameters and correlations to optimize method performance. Regulatory Compliance : Ensure compliance with regulatory requirements and support filings applying principles described e.g. in recent ICH guidelines. What you-ll bring to the role Leadership Skills : Proven ability to lead and inspire a team of scientists, with a focus on achieving team and organizational goals. Excellent communication and interpersonal skills, with the ability to engage effectively at all levels of the organization. People Development : Commitment to the growth and development of team members, with a track record of successful mentoring and coaching. Strong problem-solving abilities and a strategic mindset. Technical and Scientific Expertise : Extensive experience in physicochemical analytical method development, including (U)HPLC, CE and other relevant techniques. QbD Principles : Strong understanding of QbD principles and their application to analytical method development. Expertise in Automation and Data Modeling : Experience with advanced analytical technologies and data analysis tools to enhance efficiency and decision-making. Expertise in Process Analytical Technology (PAT) Desirable requirements University degree (PhD or equivalent is desirable) in life sciences Minimum of 10 years of proven experience in the pharmaceutical industry Minimum of 5 years in a leadership position with successful performance and track record of leading teams Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Pharmaceuticals Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No
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16.07.2024

Novartis AG

AD Product Manager, Drug Candidate Selection Software Applications

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10008985 Jun 21, 2024 Switzerland Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process - both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams- culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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14.07.2024

Novartis AG

Data Science Innovation Fellow, Structural Bioinformatics

  • Novartis AG

  • Basel

  • 14.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10010397 Jul 09, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in computational and data science, AI/ML methodology, protein science, high throughput screening as well as modeling/computer-aided drug design, you will leverage state-of-the-art AI methodology and unique internal datasets to model protein-protein and protein-ligand interactions and drive drug discovery efforts. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage large, proprietary data sets to fine-tune innovative AI models for protein-ligand structure predictions. Design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Collaborate with cross-functional teams and apply the latest structural AI models to real world drug discovery projects. Explore the application of the latest structure-based AI methods to drug discovery workflows and present your findings to the scientific community at BR (Biomedical Research) Role requirements : PhD in computational biology, cheminformatics, structural biology or equivalent, with extensive computational experience (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to protein modeling, drug discovery or small molecule design. Strong background in structural AI methods (e.g., Alphafold, Rosetta Fold, Openfold). Proficiency in Python and machine learning libraries (e.g., TensorFlow, PyTorch, Jax) in high performance computing/cloud computing environments (e.g. AWS). Experience with protein-ligand interaction prediction and drug discovery workflows. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No Apply to Job(link is external)
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09.07.2024

Novartis AG

Associate Director (m/f/d) Method Expert Team (80-100%)

  • Novartis AG

  • Basel

  • 09.07.2024

  • Festanstellung 80-100%Management / Kader

Festanstellung 80-100%

Management / Kader

Basel

Job ID REQ-10008316 Jun 05, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Are you passioned to lead a team of Method Development Experts? Have you successfully developed analytical methods based on QbD Principles? Have you used automation solutions for method development? Do you thrive on challenges and enjoy creating new physicochemical methods for biopharmaceutical molecules? Would you be willing to develop and support your team associates in their professional growth? Are you attracted to living in a vibrant region of Europe with abundant cultural and outdoor activities? If you answered "yes" to all of these questions, then we want you to join the Novartis Process Analytical Sciences team in Basel, Switzerland. Our team develops Biologics drug substance and drug products, from candidate selection to launch, emphasizing agility, innovation, and scalability to best serve our portfolio, partners, and patients. About the Role Your key responsibilities As Associate Director you will lead the Method Expert Team of Process Analytical Sciences at our TRD Biologics site in Basel. Your responsibilities include, but are not limited to: Operational manager for approx. 7+ associates in total Collaboration and Leadership : As a team lead, you will be responsible for providing technical and scientific guidance but also to inspire your team. You will work with global cross-functional teams and manage interfaces e.g. with research, process development, quality assurance, scientific office, and regulatory affairs, e.g. to ensure alignment on method development or Process Analytical Technology (PAT) strategies. Method Development and Optimization using Quality-by-Design (QbD) Principles : Drive the physicochemical analytical (PCA) method development and optimization of assigned pipeline projects for all relevant sample matrices (Drug Substance, Drug Product, Intermediates). Provide guidance on experimental designs, risk assessments, and the use of statistical tools to ensure the development of robust and reliable analytical methods. Drive innovation programs: Advanced Instrumentation and Technology : Leverage advanced analytical instrumentation and emerging technologies to enhance existing analytical methods. Miniaturization and Automation : Explore opportunities for miniaturization and automation to increase throughput, reduce sample and reagent consumption, and enhance efficiency. Data-Driven Approaches : Utilize data analytics, machine learning, and artificial intelligence to analyze large datasets and develop data-driven approaches for method development. Identify critical quality attributes, process parameters and correlations to optimize method performance. Regulatory Compliance : Ensure compliance with regulatory requirements and support filings applying principles described e.g. in recent ICH guidelines. What you’ll bring to the role Leadership Skills : Proven ability to lead and inspire a team of scientists, with a focus on achieving team and organizational goals. Excellent communication and interpersonal skills, with the ability to engage effectively at all levels of the organization. People Development : Commitment to the growth and development of team members, with a track record of successful mentoring and coaching. Strong problem-solving abilities and a strategic mindset. Technical and Scientific Expertise : Extensive experience in physicochemical analytical method development, including (U)HPLC, CE and other relevant techniques. QbD Principles : Strong understanding of QbD principles and their application to analytical method development. Expertise in Automation and Data Modeling : Experience with advanced analytical technologies and data analysis tools to enhance efficiency and decision-making. Expertise in Process Analytical Technology (PAT) Desirable requirements University degree (PhD or equivalent is desirable) in life sciences Minimum of 10 years of proven experience in the pharmaceutical industry Minimum of 5 years in a leadership position with successful performance and track record of leading teams Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No Apply to Job(link is external)
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07.07.2024

Novartis AG

Data Science Innovation Fellow - Renal Translational Research

  • Novartis AG

  • Basel

  • 07.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012381 Jun 25, 2024 Switzerland Summary You are encouraged to apply for our Data Science Innovation Fellowship, which is a three-year post-doctoral research program to augment the way we approach drug discovery. The fellow will have the unique opportunity to train in data science and AI for biomedical research. As a fellow, you will apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will participate on a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying innovative data approaches in collaboration with a vibrant community of over 300 data scientists globally. The program provides a unique platform to access real-world, biomedical data at scale, rarely available in academia. Working with experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with options for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Your project will evolve practices in disease target identification and drug discovery through strengthening our ability to translate mechanistic insights gained from preclinical models to human kidney diseases. Developing a more sophisticated understanding of drug-kidney interactions is a crucial step towards creating successful drugs. To this end, you will use your quantitative background and leverage large-scale data to derive mechanistic insights from preclinical models relevant to human kidney biology and pathophysiology. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Advance methods and practices in spatial transcriptomics, including integrated histology image and transcriptomics analysis at scale. Explore novel multimodal and transfer learning analysis approaches towards advances in translatable kidney function assessment. Leverage a knowledgebase of hundreds of rodent studies to characterize the range of notable observations made on preclinical and patient kidney data. Uncover and seize opportunities for drug development by identifying relationships in large-scale datasets that can guide preclinical safety evaluations and novel target hypotheses. Collaborate closely with colleagues in toxicology, pathology, early discovery, and data sciences. Foster the role of data science and AI in drug discovery by implementing best practices and making data more accessible. Communicate research results to both internal and external audiences, such as scientific conferences and publications. Role requirements : PhD in a quantitative field (data science, machine learning, computer science, statistics) or life sciences, preferably with multidisciplinary background (chemoinformatics, bioinformatics, biomedical engineering, AI/ML in drug discovery or life sciences). PhD students in the last year of their thesis work, are eligible to apply. Solid understanding of statistics, machine learning and deep learning; Demonstrated knowledge of data visualization and exploratory analysis. Knowledge of Python and/or R, as well as machine learning/deep learning libraries. Experience with generative algorithms and explainable AI is a plus. Experience with reproducible data science tools and practices. Strong publication record or other scientific achievements (i.e. awards, patents, grants, public code repository) Highly effective analytical, communication, presentation, and organizational skills Passion for research and boundless curiosity. Team player. Strives for continuous learning (scientific and technical). #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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06.07.2024

Novartis AG

Principal Scientist I - Toxicology (80-100%*)

  • Novartis AG

  • Basel

  • 06.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10009448 Jun 04, 2024 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking to hire a motivated candidate with a strong background in cellular and molecular immunology to join our Translational Immunology Unit in Basel within our Biomedical Research division. This is a unique opportunity to apply your deep knowledge of immunology to enable state-of-the-art cross-species immune system safety assessments for novel life-saving medicines during early and late phases of development. In collaboration with preclinical and clinical teams as well as external academic partners, you will lead innovative in vivo and in vitro experimental approaches to assess hazards and risks for drug-induced immunopathology and immune-mediated toxicity. Your contributions will enhance and accelerate the drug discovery and development portfolio of Novartis, bringing forward effective and safe medicines. About the Role Your responsibilities include, but are not limited to: Contribute and perform relevant experimental methods and scientific judgement to cross-species immune safety assessments introducing, developing, implementing, validating, and maintaining state-of-the-art technologies and laboratory procedures. Perform target reviews and translational immune system safety assessments for early and late development projects. Interface with internal clinical and preclinical teams and manage external academic collaborations. Interface with regulatory agencies. Present scientific/technical work and achievements at internal / external meetings. Publish results in internal repositories, in peer reviewed journals and as patent applications, as appropriate. Minimum requirements: Education: MD/DVM and/or PhD with strong experience (3-5 years) in immunology and infection diseases biology. Extensive experimental immunology with a strong research profile in both human and preclinical species. Good understanding of drug-induced immune reactions. Excellent communication skills and fluency in oral and written English. Knowledge of the scientific disciplines involved in drug safety assessment, including relevant laboratory procedures related to safety risk management, as well as experience with large data analysis will be advantageous. Proficiency with major state-of-the-art immunology technologies and approaches. Proven expertise in scientific and technical problem-solving, ideally within an international, multi-disciplinary environment. Proven experience supervising scientists, leading projects and working cross-teams. Desirable requirements: Excellent scientific publication record. Good scientific network with academic institutions. Proven program and project management skills and conflict solving abilities in matrix environments. *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No Apply to Job(link is external)
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06.07.2024

Novartis AG

Data Science Innovation Fellow

  • Novartis AG

  • Basel

  • 06.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012275 Jul 09, 2024 Switzerland Summary Data Science Innovation Fellow Computed Aided Drug Design About the Role About the role We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in data science, AI/ML methodology, computer-aided drug discovery, cheminformatics and medicinal chemistry as well as pharmacokinetics, you will leverage state-of-the-art AI methodology and unique internal datasets to investigate multi-objective optimization in combination with generative models to accelerate drug discovery efforts. Start date: Autumn 2024 Key responsibilities As a Data Science Innovation Fellow, you will: Leverage proprietary data sets to evaluate and refine modern optimization algorithms in the context of generative chemistry. Apply a deep understanding of foundation models, including pre-trained and large language models, to leverage multi-objective optimization in generative AI applications. Collaborate with cross-functional teams in drug discovery projects; design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Explore the application of latest optimization, predictive and generative AI models to drug discovery and present your findings to the scientific community at conferences and in publications. Be part of a unique organization and work with an interdisciplinary team of highly accomplished scientists to push the frontiers of AI in drug discovery. Role requirements : PhD in computational chemistry, cheminformatics, computer science, mathematics, statistics or equivalent with a strong focus on machine-learning (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to drug discovery or small molecule design. Proficiency in Python and deep learning frameworks (e.g. Pytorch, Tensorflow, Keras), solid knowledge of statistics, machine learning and deep learning algorithms. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to re-imagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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04.07.2024

Novartis AG

Principal Scientist II Drug Discovery - Kidney Diseases (80-100%*)

  • Novartis AG

  • Basel

  • 04.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10006954 May 15, 2024 Switzerland Summary Location: Basel, Switzerland or Cambridge Mass, US Full time, onsite, #LI-onsite We are seeking an innovative and dynamic scientist with broad expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease. In this role, you will be responsible for driving research programs focused on delineating the key mechanisms involved in proteinuric kidney diseases and progressing new targets towards drug discovery. This individual will join the Renal Research team within Disease Area X (DAx) in Biomedical Research and report to the Head of Renal Research. About the Role Major accountabilities: Contribute to the Biomedical Research drug discovery process with the goal of progressing the development of new therapeutic options for patients with chronic kidney diseases. Formulate novel target hypothesis based on human disease mechanisms using deep and broad scientific expertise in renal physiology and pathophysiology of proteinuric kidney diseases. Design and execute in vitro and in vivo research plans to deliver high quality data-driven package and enable project decisions. Deliver impact to projects by identifying technical trends, both internal and external to your discipline. Lead multi-disciplinary project team(s) to portfolio transitions a/o decision milestones. Enable partnerships with data scientists, external partners, and individuals across Biomedical Research Disease Areas and platform functions. Develop and communicate project strategy, scientific vision, and data to key stakeholders. Manage and develop a team of research scientists. Develop and maintain external relationships/contacts. Essential requirements: A PhD and/or MD degree with postdoctoral experience and a minimum of three years of research in renal biology and physiology, preferably in the pharmaceutical or biotechnology industry. In-depth knowledge of kidney (patho-)physiology, including cultivation and analysis of complex renal cell-based platforms, e.g. 3D kidney organoids, primary 2D/3D endothelial or epithelial cell systems. Extensive “hands-on” experience and proven track-record in the use of a wide range of cellular, biochemical and genome editing methods and technologies to unravel complex cellular signaling pathways. Proficiency in “state of the art” computational and analytical approaches and comfortable with analyzing large scale genetic, NGS and single cell datasets. A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases. Ability to lead a project and plan ahead, be well organized and effectively use resources to execute experiments and deliver high quality data in a timely fashion. A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts. Experience in leading and mentoring associates and cross-functional teams. Excellent oral and written communication skills (in English) are essential. *Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external)
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03.07.2024

Novartis AG

Data Science Innovation Fellow - Histopathology Foundation Models

  • Novartis AG

  • Basel

  • 03.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013211 Jun 26, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Over the period of three years, you will conceptualize and develop general-purpose Histopathology Foundation Models by leveraging thousands of whole-slide histopathology images from our internal data archives. You will be deeply embedded in our Computational Pathology and Artificial Intelligence & Computational Science teams and will work on large-scale representation learning approaches to build models that will lay the foundation of AI-enhanced pathology-based applications within Novartis. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Implement the state-of-the-art and design custom self- and weakly-supervised algorithms to build Foundation Models for histopathology data. Work as a team member on AI research projects independently, focusing on large-scale imaging data and practicing scientifically rigorous and reproducible methodology. Collaborate with other AI specialists, data architects, software engineers and pathologists within Biomedical Research on applications in the histopathology domain. Engage with diverse stakeholders in non-clinical as well as clinical settings. Build a bridge between academia and industry partners. Keep ahead of the latest developments in the field and bring curious and critical thinking to the team. Role requirements : PhD in Computer Science, Machine Learning, or a related field with a focus on image and vision applications (PhD students in the last year of their thesis work, are eligible to apply). Strong programming experience in python and proficiency in at least one main deep learning framework (PyTorch/TensorFlow/JAX). Proven experience in implementing state-of-the-art machine/deep learning algorithms. Scientific publications in AI/ML conferences and/or in journals with a focus on computational biology/medicine. Ability to clearly communicate technical concepts to a variety of audiences, including scientists, engineers, and subject matter experts from other domains. Familiarity with working on high-performance computing systems and/or cloud computing environments and version controlling is nice to have. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

QC Analyst I (Temporary) 2 years contract

  • Novartis AG

  • Stein

  • 16.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390991BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient-s T-cells, before returning them with the potential to save a patient-s life. This is a unique and novel personalized treatment where we work with the patient-s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities:- Your responsibilities include, but are not limited to: Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing Work on shifts covering daytime / evening and one or both weekend days Knowledge of LabWare LIMS and/or other QC data systems Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements Sample storage and management Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes
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16.07.2024

Novartis AG

QC Analyst I (Temporary) 1 year contract

  • Novartis AG

  • Stein

  • 16.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390993BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient-s T-cells, before returning them with the potential to save a patient-s life. This is a unique and novel personalized treatment where we work with the patient-s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities:- Your responsibilities include, but are not limited to: Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing Work on shifts covering daytime / evening and one or both weekend days Knowledge of LabWare LIMS and/or other QC data systems Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements Sample storage and management Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes
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16.07.2024

Novartis AG

Equipment Operator

  • Novartis AG

  • Stein

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Stein

Job ID REQ-10008960 May 28, 2024 Switzerland Summary -Gerätebediener -Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. -Service-Operator -Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität -Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You-ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. Why-Novartis? 766 million lives were touched by Novartis medicines in 2021, and while we-re proud of this, we know there is so much more we could do to help improve and extend people-s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.- Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en\_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Pharmaceuticals Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Functional Area Technical Operations Job Type Full time Employment Type Befristet (Befristet) Shift Work No
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03.07.2024

Novartis AG

QC Analyst I (Temporary) 2 years contract

  • Novartis AG

  • Stein

  • 03.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390991BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient’s T-cells, before returning them with the potential to save a patient’s life. This is a unique and novel personalized treatment where we work with the patient’s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities: Your responsibilities include, but are not limited to: • Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary • Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing • Work on shifts covering daytime / evening and one or both weekend days • Knowledge of LabWare LIMS and/or other QC data systems • Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements • Sample storage and management • Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes Apply to Job(link is external)Access Job Account(link is external)
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