Novartis AG

Summary Der CBC Equipment Specialist ist verantwortlich für den GMP-konformen Herstellungsprozess von Zellbanken im Basel Cell Bank Center. Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role Major Accountabilities Teilnahme an den Herstellungsprozessen Durchführung aller notwendigen Verarbeitungsschritte des Zellbankwesens mit höchstemKenntnisstand der aseptischen/niedrigen Keimbelastungstechnik (Auftauen, Zellpassage,Zellzählung und Einfrieren der Zellbank) Ausführung sämtlich zugewiesener Tätigkeiten gemäß dem Produktionsplan und der gültigenGMP-, Arbeits-,Betriebs-, Umwelt- und Sicherheitsanweisungen und -richtlinien Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagenund -räume Verantwortung für die Haushaltsführung des Produktionsbereichs (Reinigung, Ordnung, 5S, usw.) Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien(HSE) Anwendung und Durchsetzen der aktuellen GMP-Regeln Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften Education: Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen, Technischer Abschluss; Universitatsabschluss (Chemieingenieurwesen, pharmazeutische Technologie, Biotechnologie, Biochemie) fur einige Technologieplattformen erwOnscht oder gleichwertige Erfahrung Languages: Grundkenntnisse in Englisch und Beherrschung der Landessprache des Standorts - German Experiences: Mindestens 2 Jahre abgeschlossene Berufserfahrung als Novartis-Gerätebediener oder (vorzugsweise) 5 Jahre in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a CDD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements: • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred • Fluent oral and written English • Minimum 7 years experience in clinical research or drug development • Working knowledge of the assigned disease area is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is the clinical leader of a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase), or a large, complex trial, under the leadership of the (Sr.) GPCH. About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059144 Aug 22, 2025 Switzerland Summary As a Clinical Process Manager (CPM) in TRD GCS Clinical Packaging Operations, you will take full operational responsibility for the production of clinical trial materials, including primary packaging, labeling, and dispensing. You will act as a subject matter expert, lead process improvements, ensure compliance with GxP standards, and drive a culture of quality and performance on the shop floor. This role requires strong leadership, cross-functional collaboration, and a proactive approach to managing risks, deviations, and continuous improvement initiatives. The role is part of the team GCS Operations and reports directly to Operations Lead. #LI-Hybrid About the Role Key Responsibilities Take end-to-end responsibility for the production of primary packaged and clinical finished goods. Define, manage, and continuously improve processes related to clinical packaging, label printing, and dispensing . Provide leadership on the shop floor , ensuring daily operations meet quality, quantity, and timeline targets. Act as Subject Matter Expert (SME) in assigned areas and represent Clinical Packaging in relevant TRD and GCS activities. Drive a culture of quality and performance , using appropriate KPIs to monitor and improve operational outcomes. Identify process deficiencies and lead improvement projects to enhance efficiency and compliance. Lead deviation investigations , technical complaints, and non-Right First Time (RFT) cases; define and implement preventive and corrective actions. Ensure all process-related documentation is accurate, up to date, and compliant with internal and external guidelines. Communicate operational challenges and risks to internal and external stakeholders, adapting priorities as needed. Support and prepare for internal and external inspections , ensuring readiness and compliance. Provide training and guidance to colleagues on procedures, risks, and compliance expectations. Act as a role model for company values and behaviors, promoting a collaborative and accountable work environment. What you-ll bring to the role: Solid practical experience in chemical / pharmaceutical industry, ideally with at least 3 years of experience in a similar position within Pharma company (Near) native level of proficiency in German, fluent English Good knowledge about the Drug Development and Clinical Supply processes Excellent organization and planning skills, experience in Project management Evident knowledge of relevant regulations (e.g. GMP, HSE etc.) Demonstrated problem-solving attitude and idea generation skills Advanced communication, negotiation and interpersonal skills Experience in delivering presentations Fundamental Leadership skills (Intermediate for Associate Team Head) Ability to work in interdisciplinary teams Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Disclaimer*: Some restrictions on flexible working options may apply and will be discussed during interview if applicable You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team-s representative of the patients and communities we serve. Hiring decisions are only based on the qualification for the position, regardless of gender, ethnicity, religion, sexual orientation, age and disability. The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Adjustments for Applicants with Disabilities: The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regulär Shift Work No

Job ID REQ-10059955 Aug 19, 2025 Switzerland Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Drug Product Project Leader (FPL) to lead drug product formulation and manufacturing process development. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Major accountabilities: Be accountable for all formulation and manufacturing process deliverables including scientific documentation, design of experiments of parenteral products, batch records, deviations, change controls, CAPAs, tech transfer, and reports. Drive DP development, manufacturing process transfers and supply activities with scientific and technological excellence Work closely with cross functional teams both internal and external to provide technical input for the development and manufacturing process (including CRO and CMOs). Provide technical support to compile technical regulatory documentation and responses to regulatory agencies as needed. Assist with writing and reviewing of CMC documentation associated with project or manufacturing changes. Key Skills Formulation Expertise: Experience developing injectable drugs, including solutions, suspensions, and aseptic formulations. Knowledge of RNA-based therapies (e.g., siRNA, mRNA) and drug delivery systems like pre-filled syringes or vials. Process Development : Skills in designing manufacturing processes and transferring them to production environments. Familiarity with aseptic drug manufacturing and methods like QbD. Regulatory Knowledge: Understanding of GMP and preparing technical documentation for regulatory submissions. Analytical Thinking: Designing experiments (e.g., DoE) and analyzing data to improve formulations and manufacturing processes. Collaboration & Communication: Strong teamwork skills for working with internal teams and external partners (e.g., CROs/CMOs). Clear communication and ability to write reports, technical documents, and regulatory responses. Problem-Solving: Ability to handle deviations, implement corrective actions, and improve manufacturing processes. Innovation: Interest in advancing RNA drug delivery platforms and contributing new ideas to the field. Preferred Technical Experience Working knowledge of oligonucleotide-based therapies (e.g., ADCs, proteins, RNA-based drugs). Familiarity with process development for clinical-grade parenteral drug products. Proven experience in related fields such as pharmaceuticals, biotechnological product development, and advanced drug delivery platforms. Required Qualifications: Ph.D., Master-s or Bachelor-s Degree in Chemistry or related disciplines: With 2+ years (Ph.D.), 5+ years (Master-s), or 8+ years (Bachelor-s) biopharmaceutical experience. Proven expertise in formulation and manufacturing process development for parenteral and aseptic products. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Co-supervised by Novartis Pharmacometrics Department and Uppsala University in Sweden. The INVENTS project consortium (https://invents-he.eu/), in which Novartis is an associated partner, aims at developing methods, workflows, and evidence-tools to improve the development and evaluation of evidence in rare diseases and pediatric populations. Pharmacometrics (PMX) models are often used to support drug development in these settings, however, there is limited research on when the dose response relationship inferred through pharmacometrics models has the intended causal interpretation. The aim of this project is to advance our understanding of the potentials and limitations of pharmacometrics modeling approaches from an estimand and causal inference perspective for the development of new medicines in small sample size populations such as rare diseases and pediatric populations. Preferred start date: ASAP Duration: 4 years About the Role Major accountabilities: Assessing types of intercurrent events that can impact the interpretation or even the existence of measurements of the efficacy or safety endpoint of interest in the target population. Assessing and contrasting strategies, including the required assumptions, to handle such intercurrent events. Developing causal inference methodologies adapted to pharmacometrics models, to identify valid estimators (i.e., yielding unbiased estimates) of the estimand. Developing tools such as model diagnostics that help assess whether a model can be interpreted causally. Performing simulation studies and analyze real clinical data to assess the impact and limitations of the proposed approaches on the evidence generated. Minimum Requirements: Master’s level degree or equivalent in a relevant field such as statistics, pharmacometrics, mathematics, engineering, biomedicine, or medicine, with strong interest in causal inference. Strong interest in bridging principles from causal inference and pharmacometrics. Good interpersonal and communication skills. Exposure to scientific computing and programming Desirable requirements: Expertise or coursework in causal inference. Expertise in R. Experience with modeling & simulation software such NONMEM or Monolix Suite. Languages : Fluency in English (IELTS (academic) total score of 6.5 or higher with no section less than 5.5), or equivalent. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a edical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060747 Aug 29, 2025 Switzerland Summary Co-supervised by Novartis Pharmacometrics Department and Uppsala University in Sweden. The INVENTS project consortium ( https://invents-he.eu/ ), in which Novartis is an associated partner, aims at developing methods, workflows, and evidence-tools to improve the development and evaluation of evidence in rare diseases and pediatric populations. Pharmacometrics (PMX) models are often used to support drug development in these settings, however, there is limited research on when the dose response relationship inferred through pharmacometrics models has the intended causal interpretation. The aim of this project is to advance our understanding of the potentials and limitations of pharmacometrics modeling approaches from an estimand and causal inference perspective for the development of new medicines in small sample size populations such as rare diseases and pediatric populations. Preferred start date: ASAP Duration: 4 years About the Role Major accountabilities: Assessing types of intercurrent events that can impact the interpretation or even the existence of measurements of the efficacy or safety endpoint of interest in the target population. Assessing and contrasting strategies, including the required assumptions, to handle such intercurrent events. Developing causal inference methodologies adapted to pharmacometrics models, to identify valid estimators (i.e., yielding unbiased estimates) of the estimand. Developing tools such as model diagnostics that help assess whether a model can be interpreted causally. Performing simulation studies and analyze real clinical data to assess the impact and limitations of the proposed approaches on the evidence generated. Minimum Requirements: Master-s level degree or equivalent in a relevant field such as statistics, pharmacometrics, mathematics, engineering, biomedicine, or medicine, with strong interest in causal inference. Strong interest in bridging principles from causal inference and pharmacometrics. Good interpersonal and communication skills. Exposure to scientific computing and programming Desirable requirements: Expertise or coursework in causal inference. Expertise in R. Experience with modeling & simulation software such NONMEM or Monolix Suite. Languages : Fluency in English (IELTS (academic) total score of 6.5 or higher with no section less than 5.5), or equivalent. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a edical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary The Senior Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Sr CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 10 years of experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a dedicated and high-performing team, united by a shared commitment to create significant value for Novartis. You will be responsible for ensuring the adherence to the internal control framework (specific for Novartis Treasury) and will be responsible for various reporting and accounting matters, including month-end closing, asset management performance and reporting to various authorities (SNB, SIX, etc.). In addition, you will be accountable for the risk management with financial counterparties under the applicable derivative regulation frameworks and the Novartis Treasury Guideline. About the Role Key Responsibilities: Responsible for various (financial) reporting and accounting matters, including preparation of journal entries, month-end closing activities, preparation of FCRS reporting schedules, SIX reporting, contribution to Novartis annual report and analysis of Novartis Treasury cost center budget. Coordination and support in SOX404 Treasury Controls; support Financial Control Cycle, maintain matrix, perform controls (reconciliations), controls testing and follow up on deficiencies / improvement areas. Business Service Owner of Middle Office systems (e.g., FIS Quantum, FactSet); Ensure good collaboration with external providers and Novartis Treasury IT. Monitor interfaces, ensure data quality, develop new reporting and analysis capabilities together with key stakeholders. Business Partner for key stakeholders that use Treasury systems and processes, for example Treasury Investment Management / Novartis Pension Fund 1 and Novartis Venture Fund and NIBR. Provide performance and currency overlay reporting, perform ad hoc analyses, ensure complete & accurate reporting (including ESG reporting for Pension Fund 1). Responsible for various Risk Management activities, such as adherence to counterparty credit limit framework and investment controlling, risk identification / indication (“Early Warning Process”). Ensure relevant agreements (ISDA, EMIR/FinMIA, LEI, etc.) with financial counterparties are in place, maintained in a database and regularly monitored for validity. Lead Middle Office projects, drive improvements and contribute to Treasury initiatives. Essential Criteria: Master or Bachelor’s Degree in Finance, Economics, or equivalent Strong understanding of Financial Compliance & Controls Sound knowledge of Corporate Treasury or banking sector is a strong plus. Proven experience in similar Treasury, Accounting and Tax role preferable at a “Big 4” audit firm Good SAP and MS Office (Excel) skills, knowledge of FIS Quantum is a benefit. Fluent in English, German is a plus Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Job Description Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and xRNA Therapüeutics, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Scientist design, plan, perform and document scientific lab experiments for the preparation and timely development of drug product formulations and manufacturing processes in collaboration within a multifunctional project team coordinated by a Project leader. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Key Responsibilities: Design, plan, perform, interpret, and report results of scientific experiments for the preparation and timely delivery of drug product formulation and manufacturing process Lead and manage all project/local network activities, support team members, participate in project teams, and contribute to overall TRD strategies and goals Conduct experiments related to formulation and process development of oligonucleotides or RLT Communicate and address problems, perform literature searches under moderate guidance Contribute to the maintenance of lab instruments Contribute to transfer of processes to non-GMP and GMP manufacturing facilities Review and approve batch documentation, support deviations. Ensure adherence to HSE rules and guidelines. Required Qualification: Bachelor’s or Master’s degree (preferred) in Chemistry, Pharmaceutical Science, or a related field. A minimum of 3 years of experience in the pharmaceutical industry working on parenteral product development. Skills: Technical Knowledge: Expertise in parenteral drug product formulation and process development. Familiarity with oligonucleotide and peptide therapeutics, as well as radioligand therapies. Experience with lab techniques and tools like lyophilization, spray drying, analytical equipment, and autoclaves. Scientific and Analytical Skills: Ability to design, plan, perform, and document scientific experiments for drug formulation and process development. Troubleshooting and interpreting experimental outcomes, with the ability to conduct literature searches. Process Development: Knowledge of transferring processes to GMP and non-GMP manufacturing facilities. Experience reviewing and approving batch documentation, supporting deviations, and ensuring compliance. Collaboration and Teamwork: Comfortable working in multifunctional project teams and contributing to overall development strategies. Communication Skills: Strong verbal and written communication skills, including the ability to present ideas clearly and write scientific/technical documents. Computing Skills: Familiarity with software tools and computer systems relevant to laboratory work. Attention to Compliance : Adherence to Health, Safety, and Environment (HSE) guidelines and rules to maintain a safe and effective workspace. Languages : Fluent English (spoken and written) is required. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Head of Data for Biomedical Research (BR) is responsible for developing and executing the Data and Digital (D&D) organization's data strategy to support research and early development. This role includes setting the vision for data utilization, managing data governance, and fostering a data-driven culture across the organization. The Head of Data will work closely with key stakeholders to ensure data quality, accessibility, and compliance across functions. As a member of the Research Informatics Leadership Team, this leader will report directly to the Global Head of Digital, Informatics, and AI. About the Role Major accountabilities but not limited to: Develop and implement comprehensive data strategies that align with business objectives and research priorities. Advise management on strategic direction, scope and approach. Promote and foster a data-driven culture, enhancing data literacy across the organization. Monitor and evaluate the effectiveness of data strategies, adjusting as needed to achieve desired outcomes. Stay informed about emerging trends and technologies in data management and apply innovative solutions to enhance data utilization. Establish and oversee data governance frameworks, ensuring high standards of data quality, accessibility, and compliance. Align on and contribute to Novartis Enterprise Data Management framework. Define and implement data standards, policies, and procedures, driving interoperability across systems and processes. Lead efforts to validate, review, and reconcile data, maintaining high-quality standards across all datasets. Integrate and harmonize data across multiple systems and functions, facilitating seamless data flow. Develop tools, workflows, and integration solutions to eliminate data silos and enhance collaboration across teams. Enable access to high-quality, reliable data for research and development teams to drive decision-making. Facilitate effective collaboration between data teams and business stakeholders, ensuring alignment with organizational goals. Build strong relationships with internal and external stakeholders, including external partners, to drive innovation and data-sharing opportunities. Communicate data strategies, insights, and recommendations to stakeholders at all levels of the organization. Lead a growing organization expected to reach 35+ people. Minimum Requirements: PhD or master’s degree in computer science, data science, AI, machine learning, or a related discipline. 15+ years of experience in data strategy, management, and governance, with a demonstrated understanding of advanced data methodologies applied to drug discovery and development in the pharmaceutical/biotech industry. Experience leading multidisciplinary, global teams and operating successfully in matrixed, fast-paced environments. Proven ability to manage complex portfolios and work with diverse stakeholders to prioritize resources and meet business needs. Strong leadership and communication skills, with the ability to influence stakeholders and drive organizational change. Strategic thinker with a vision for data-driven decision-making and a strong understanding of data management, governance, and analytics. In addition to traditional data management skills, the ideal candidate would possess competency in the following advanced data technologies: deploying scalable data solutions on cloud-native data platforms, experience with vector databases, implementing a decentralized, domain-driven data architecture, a solid grasp of ML Ops principles including the data centric aspects of model training, deployment and monitoring, experience implementing data observability tools, and familiarity with graph databases. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Head of IMEX Program will spearhead the International Medical Excellence (IMEX) transformation program across Novartis International business unit, with special focus on the top 11 markets. This role demands a strategic and dynamic leader capable of driving the program’s vision, strategy, and execution, ensuring alignment with the overall business objectives. The IMEX Program Lead will work closely with the executive committee, IMA regional/country leaders, and cross-functional teams to optimize Medical Affairs practices and achieve significant growth, launch excellence and executional efficiencies in the key markets. About the Role Key Responsibilities: IMEX Program Leadership and Strategy: Lead the development and execution of the IMEX transformation program across all designated regions and markets. Collaborate with the executive committee to define and communicate the program’s vision, mission, and objectives. Develop a comprehensive roadmap for the IMEX program, including key milestones, timelines, and resource allocation. Design and implement program operating model, work architecture and governance that enables the transformation first for 4 key markets and then at scale for all international markets. Stakeholder Engagement and Management: Engage with senior leadership and key stakeholders to ensure alignment and support for the IMEX program. Foster strong relationships with regional and market leaders to facilitate the successful implementation of IMEX initiatives. Act as the primary point of contact for all IMEX-related activities and communications. Operational Execution: Oversee the roll-out of IMEX 1.0 across Wave 1, Wave 2, and Wave 3 countries, ensuring readiness and successful implementation. Bridge MarTech gaps and finalize MarTech workplan Coordinate with cross-functional teams, including GMA, DAP, TA, IT, and finance, to ensure integrated and efficient program execution. Identify, mobilize, and onboard relevant resources for Wave 1 roll-out (international and in-market) Implement and monitor key performance indicators (KPIs) to track progress and impact, making data-driven adjustments as necessary. Change Management: Lead change management initiatives to ensure smooth adoption of IMEX practices and processes within the organization. Develop and execute a communication plan to keep all stakeholders informed about program progress, successes, and challenges. Provide training and support to teams to enhance their capabilities and adoption of new tools and processes. Continuous Improvement: Identify and implement best practices to continuously enhance the IMEX program’s effectiveness and efficiency. Leverage data and analytics to gain insights and drive improvements in IMA strategies. Stay abreast of industry trends and innovations to keep the IMEX program at the forefront of Medical Affairs excellence. Talent and Culture Builds a high performing program team – with right capabilities, skills and mindsets Role model ICU and foster the culture that empowers with accountability, enables collaborations, and drives performance as ONE team Essential requirements: PhD or MD. Other degree like MBA or Project Management certification is a plus Minimum of 10 years of experience in Medical Affairs within the pharmaceutical or healthcare industry. Proven track record of leading large-scale transformation programs. Experience working in a multinational environment with cross-functional teams. Collaborative – fosters an Enterprise-first culture / mindset, demonstrates high emotional intelligence, connects cross-divisionally to build alignment across innovative ideas. Superior communication and interpersonal skills, with the ability to influence and engage stakeholders at all levels. Embraces and drives change, continually seeking ways to improve and innovate. Has track-record of operational innovation. Results-Oriented: Focused on achieving measurable outcomes and delivering value to the business. Proficiency in data analysis and performance management.Knowledge of AI and data-driven tools and techniques. Experienced people leader and maintains leadership role under pressure & during ambiguity.Strategic leadership - demonstrates the courage to assume personal accountability in challenging situations. Able to think broad and deep across different levers and align work to expected outcomes. High integrity – achieves objectives with high ethical standards. Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Drug Product Project Leader (FPL) to lead drug product formulation and manufacturing process development. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Major accountabilities: Be accountable for all formulation and manufacturing process deliverables including scientific documentation, design of experiments of parenteral products, batch records, deviations, change controls, CAPAs, tech transfer, and reports. Drive DP development, manufacturing process transfers and supply activities with scientific and technological excellence Work closely with cross functional teams both internal and external to provide technical input for the development and manufacturing process (including CRO and CMOs). Provide technical support to compile technical regulatory documentation and responses to regulatory agencies as needed. Assist with writing and reviewing of CMC documentation associated with project or manufacturing changes. Key Skills Formulation Expertise: Experience developing injectable drugs, including solutions, suspensions, and aseptic formulations. Knowledge of RNA-based therapies (e.g., siRNA, mRNA) and drug delivery systems like pre-filled syringes or vials. Process Development : Skills in designing manufacturing processes and transferring them to production environments. Familiarity with aseptic drug manufacturing and methods like QbD. Regulatory Knowledge: Understanding of GMP and preparing technical documentation for regulatory submissions. Analytical Thinking: Designing experiments (e.g., DoE) and analyzing data to improve formulations and manufacturing processes. Collaboration & Communication: Strong teamwork skills for working with internal teams and external partners (e.g., CROs/CMOs). Clear communication and ability to write reports, technical documents, and regulatory responses. Problem-Solving: Ability to handle deviations, implement corrective actions, and improve manufacturing processes. Innovation: Interest in advancing RNA drug delivery platforms and contributing new ideas to the field. Preferred Technical Experience Working knowledge of oligonucleotide-based therapies (e.g., ADCs, proteins, RNA-based drugs). Familiarity with process development for clinical-grade parenteral drug products. Proven experience in related fields such as pharmaceuticals, biotechnological product development, and advanced drug delivery platforms. Required Qualifications: Ph.D., Master’s or Bachelor’s Degree in Chemistry or related disciplines: With 2+ years (Ph.D.), 5+ years (Master’s), or 8+ years (Bachelor’s) biopharmaceutical experience. Proven expertise in formulation and manufacturing process development for parenteral and aseptic products. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: this role can be based in Basel Switzerland or Cambridge MA, / East Hanover NJ USA. If applying in the US, please apply to REQ-10060708. LI - #hybrid The Novartis Strategy & Growth Therapeutic Area Strategy team for Neuroscience is seeking a new Director. This individual will support the creation and update of a holistic TA strategy for RLT, provide early-phase commercial insights to project teams, guide TA-specific internal pipeline development and external licensing / acquisitions opportunities and support integrated enterprise alignment across Biomedical Research, Development, Strategy & Growth, and the US and International Commercial units. About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the Neuroscience TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, Neuroscience and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs. To do this effectively, in-market experience in the US is critical. Analyses reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Successfully ensures accurate and timely delivery of key commercial insights for early phase projects to the program teams. Effectively manage the commercial transition from S&G to the US and International commercial units. Actively seeks input into the TA strategy from other internal experts (e.g. the Therapeutic Areas Leadership team). Successfully completes ad-hoc requests as defined. Delivery of agreed health improvement partnership projects on time and within budget. High quality contributions to other HCS group activities. Feedback from project sponsors and (internal and external) key stakeholders regarding quality of project output and interaction. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable In-depth knowledge of Neuroscience, including multiple tumor types (or track record to acquire required TA expertise effectively and rapidly) Experience with NS or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). At least 5-7 years of Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analyzing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Recent (post 2015) local US in-market experience; local US experience includes working within the US market with the local US customers, US health care systems / systems Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060684 Aug 28, 2025 Switzerland Summary Location: this role can be based in Basel Switzerland or Cambridge MA, / East Hanover NJ USA. If applying in the US, please apply to REQ-10060708. LI - #hybrid The Novartis Strategy & Growth Therapeutic Area Strategy team for Neuroscience is seeking a new Director. This individual will support the creation and update of a holistic TA strategy for RLT, provide early-phase commercial insights to project teams, guide TA-specific internal pipeline development and external licensing / acquisitions opportunities and support integrated enterprise alignment across Biomedical Research, Development, Strategy & Growth, and the US and International Commercial units. About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the Neuroscience TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, Neuroscience and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs. To do this effectively, in-market experience in the US is critical. Analyses reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Successfully ensures accurate and timely delivery of key commercial insights for early phase projects to the program teams. Effectively manage the commercial transition from S&G to the US and International commercial units. Actively seeks input into the TA strategy from other internal experts (e.g. the Therapeutic Areas Leadership team). Successfully completes ad-hoc requests as defined. Delivery of agreed health improvement partnership projects on time and within budget. High quality contributions to other HCS group activities. Feedback from project sponsors and (internal and external) key stakeholders regarding quality of project output and interaction. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable In-depth knowledge of Neuroscience, including multiple tumor types (or track record to acquire required TA expertise effectively and rapidly) Experience with NS or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). At least 5-7 years of Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analyzing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Recent (post 2015) local US in-market experience; local US experience includes working within the US market with the local US customers, US health care systems / systems Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Strategy & Growth Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area BD&L & Strategic Planning Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary As a Clinical Development Medical Director, you will be responsible for the scientific and clinical strategy of assigned clinical trials, scientific monitoring, and reporting of quality data. The Clinical Development Medical Director (CDMD) is the clinical leader of defined program level activities (e.g., submission activities, briefing books, clinical study reports, etc.) and/or a large, complex trial, under the leadership of the Global Program Clinical Head (GPCH). May also lead a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase). About the Role Major accountabilities: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the clinical development plan (CDP), data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., investigator brochures, briefing books, safety updates, submission dossiers, and responses to health authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors, and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert (CSE). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team, and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Clinical Development Head by providing medical input into CDP and clinical trial package reviews and contributing/driving development of disease clinical standards for disease areas Provide support to the GPCH or CDH in interactions with external partners (e.g., regulatory authorities, key opinion leaders, data monitoring boards, advisory boards, patient advocacy groups), internal partners (e.g., clinical trial team, Medical Affairs, Commercial, Health Economics & Outcomes Research), and decision boards) Work with BR (Novartis Biomedical Research)/Translational Medicine) to drive transition of early development projects to Transition Decision Point and with Business Development, including target identification and due diligences Ensure career development of Program Reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for Global Clinical team Minimum Requirements: MD (or equivalent medical degree) required. Training in nephrology preferred Medical Board certification preferred. 4+ years Clinical practice experience (including residency) preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) required 5+ years of experience in clinical research or drug development from the pharmaceutical/biotechnology industry, preferably spanning clinical activities in phases I through IV 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrixed environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of Good Clinical Practice, clinical trial design, statistical analysis methodology, and regulatory/clinical development processes People management experience preferred, especially at the global level (this may include management in a matrixed environment) Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards LI# HYBRID Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ulcerative colitis and Crohn's disease, along with other gastrointestinal ailments, represent a diverse array of conditions impacting millions globally. These afflictions have significant unmet medical needs and often lead to a diminished quality of life. Novartis stands at the forefront of pharmaceutical innovation in immunology, leveraging advanced scientific research to develop transformative treatments that enhance patients' lives worldwide. We are seeking a Medical Director or Executive Director of Gastrointestinal (GI) Immunology in Translational Medicine Immunology. Join us in this endeavor! You will provide medical and scientific leadership and expertise in a role that significantly impacts the drug development pipeline. 1. Drive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP) 2. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. 3. Support Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. 4. Provide scientific expert assessments and support for in-licensing opportunities, including due diligences. About the Role Major Accountabilities Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with TM TA Head and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Convene relevant (internal and external) experts to consider the proposed approach to reach TDP; present plans for approval at relevant decision boards. Be responsible for clinical portions of the Integrated Development Plan (IDP, including the Clinical Development Plan and Clinical Profiling Plan) Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Late-stage clinical projects (post-TDP, “Profiling”): In collaboration with TM TA Head or Translational Medicine Profiling Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. Drive analysis of studies and presents results to relevant decision boards. Communicate clinical team matters to GPTs and relevant BR and Development boards [and other Novartis Boards] Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Be responsible for writing TM portion of documents needed for regulatory submission through drug registration (including advisory committee and scientific advice group meetings) Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with TM TA Head, BR Research scientists, other TM line functions (BMD, CS&I, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities. This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Be accountable for compound-related biomarker strategies; works closely with Biomarker Expert in implementation. Business Development and Licensing (BD&L; in-licensing and outlicensing compounds): Participate on BD&L teams as the TM representative. In collaboration with BD&L team, evaluate the risks and benefits of potential in-licensing opportunities, identifying the strengths and weaknesses of external programs in terms of TM’s scope of responsibility. Participate in teams carrying out out-licensing of BR programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. Leadership: Lead study-specific teams/ clinical trial teams in partnership with other line functions. Lead BR-sub-team(s) on Global Project Teams for late-phase programs Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Man- agement) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific stand- ards and innovation. Key Performance Indicators Delivery of proposed Development Candidate ((B)DC) and Integrated Development Plan Approval (IDPA) milestones, and results driving decision-making for/against transition into later phase development (TDP), according to defined timelines. Delivery of Clinical pharmacology and profiling strategy including execution of studies according to timelines to support regulatory submissions and approvals. Delivery of TR plans, whether in vitro, in vivo, or in silico, to drive program strategy and clinical trial efficiency. Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results and a focus on operational excellence at all levels. Strong adherence to and modeling of Novartis values and behaviors. Impact of this role? Design and implementation of early Integrated Develop- ment Plan (IDP) and design and implementation of studies according to the IDP, enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds. This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the TDP mechanism, and driving the program after TDP by delivering key Profiling data to support regulatory submissions. Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis. Role Requirements : Education Doctoral degree, MD required in most cases. PhD or relevant scientific experience with academic track record preferred Demonstrated excellence and clinical expertise in relevant medical subspecialty. Experience/Professional Requirement: At least 5 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with level of role. Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. Demonstrated passion for science. Recognized expert in field, driving success for individual studies and projects; respected by colleagues across R&D, Development, and externally. Languages: Fluent English (oral and written). ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We offer a 6-month legal traineeship position in Legal for Corporate Functions, starting June 1, 2026! About the Role Are you interested in pursuing a career in law? We have the perfect opportunity for you! Our legal trainee position offers excellent hands-on, in-house legal experience within the dynamic and multinational environment of a leading pharmaceutical company. More than 70’000 unique individuals work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world. We are seeking a motivated and diligent legal trainee who has the courage to navigate in unknown and ambiguous legal areas and has the curiosity to learn and being exposed to interesting and challenging new legal questions. If you're passionate about making a difference and keen to kickstart your career with our in-house team, this could be the ideal role for you. We offer a 6-month legal traineeship position starting June 1, 2026 Your responsibilities include: • You'll be the backbone of our Legal team, offering essential advice in employment law (including questions related to Diversity, Equity & Inclusion), as well as litigation and investigation. You'll have the opportunity to tackle complex global and local issues, transforming challenges into solutions. • You'll get your hands on practical tasks, managing individual legal cases, but also major projects (reorganizations, divestments, implementation of new policies and processes, etc.), drafting and reviewing agreements, internal regulations, and templates. This is your chance to shift from theory to practical application, making an immediate impact. • Your role will involve in-depth legal research and the creation of legal memoranda, helping us to break down complex ideas into digestible insights. Here, your knowledge will fuel our mutual success. • You'll also play a pivotal role in reporting key legal matters to our audit committees in strict adherence to the Sarbanes-Oxley Act. What you’ll bring to the role: • Swiss Bachelor of Law (BLaw) und Master of Law (MLaw); master degree needs to be completed before start date • Excellent proficiency in English and German, both in verbal and written communication • High motivation and ability to work independently on challenging tasks and projects • Prior legal internship and knowledge in employment law is a plus Are you ready to sharpen your skills and inspire change? If you're excited to contribute and learn, apply now, and submit a cover letter that includes your motivation for the position and your availability for six months starting in June 2026. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Onsite We are looking for a dedicated QC Analyst to support Good 'x' Practice (GxP) activities in our quality department. This role involves managing quality systems, implementing operational processes, and ensuring compliance with Novartis quality standards. About the Role Key Responsibilities: Maintain compliance with current Standard Operating Procedures (SOPs), GxP-compliant documentation, and records within the Novartis quality management system. Perform and evaluate analytical tasks in a pharmaceutical laboratory, including working in shifts where necessary. Ensure the integrity of all quality assurance records and data, as applicable, and foster collaboration between your team and other functions and departments. Ensure an appropriate level of education and GxP knowledge. Support quality audits and health authority inspections. Essential Requirements: Experience in quality assurance and analytical skills. Proficiency in analytical technologies (e.g., HPLC, GC, titration). Knowledge in the use of lab-specific software (e.g., Empower, Chromeleon, TiAmo). GMP experience and technological expertise. Willingness to work in shifts. Fluency in German and English. This role is limited to 24 months. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) *Disclaimer: Some restrictions on flexible working options may apply and will be discussed during interview if applicable. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059577 Aug 11, 2025 Switzerland Summary #LI-Onsite We are looking for a dedicated QC Analyst to support Good 'x' Practice (GxP) activities in our quality department. This role involves managing quality systems, implementing operational processes, and ensuring compliance with Novartis quality standards. About the Role Key Responsibilities: Maintain compliance with current Standard Operating Procedures (SOPs), GxP-compliant documentation, and records within the Novartis quality management system. Perform and evaluate analytical tasks in a pharmaceutical laboratory, including working in shifts where necessary. Ensure the integrity of all quality assurance records and data, as applicable, and foster collaboration between your team and other functions and departments. Ensure an appropriate level of education and GxP knowledge. Support quality audits and health authority inspections. Essential Requirements: Experience in quality assurance and analytical skills. Proficiency in analytical technologies (e.g., HPLC, GC, titration). Knowledge in the use of lab-specific software (e.g., Empower, Chromeleon, TiAmo). GMP experience and technological expertise. Willingness to work in shifts. Fluency in German and English. This role is limited to 24 months. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture&nbsp ; Benefits and Rewards : Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) *Disclaimer: Some restrictions on flexible working options may apply and will be discussed during interview if applicable. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Befristet (Befristet) Shift Work No

Summary BDSS QC Bioanalytics is responsible for bioanalytical testing of Biopharmaceuticals for late-phase development projects and commercial products. Applied analytical techniques are mainly cell-based potency assays for bioactivity determination and ELISA /qPCR for the determination of process-related impurities (e.g. host-cell proteins (HCP), residual Protein A, residual DNA). About the Role We are looking for a motivated Senior QC Specialist (Lab Head) to supervise the performance of bioanalytical experiments (i.e. cell-based bioassays, ELISA and qPCR) for quality control (release, stability, and in-process control (IPC) testing) of biotech drug substances (DS) and drug products (DP) in collaboration with members of the own and cross-functional teams in a cGMP environment. Analytical method validation and transfers will be part of the position. Major Accountabilities of the role as Senior QC Specialist (Lab Head) include: • Supervision of routine QC testing activities, including line unit approval of analytical records and raw data, investigations of deviations, OOE/OOS, and analytical changes • Full compliance with regulatory and cGMP guidelines within the field of responsibility • Support of technical project teams as analytical expert • Performance of method validations (full ICH validation) and transfers, author of validation- and transfer protocols / -reports • Trending and evaluation of analytical data • Method lifecycle management for commercial products including method updates, post-approval changes, or troubleshooting • Management and coordination of internal and external customer interfaces (e.g. testing/resource requirements, setup of service level agreements) • Support in health authority inspections as subject matter expert (e.g. routine GMP inspections, pre-approval inspections) • System owner of laboratory equipment and computerized systems including initial qualification and periodic maintenance/functional testing Requirements: • PhD or equivalent education in Biology, Biochemistry, Chemistry, or related discipline • Several years of experience in analytics / quality control in a leadership role. Experience with Biopharmaceuticals desirable • Thorough knowledge of cGMP requirements • Results oriented, team player and able to work with all levels of the organization • Strong leadership and problem solving skills. Able to identify issues and develop business-friendly solutions in line with the overall compliance • Good knowledge of instrument qualification, quality metrics • Experience in audits or inspections from health authorities • Very good communication and presentation skills • Fluent English required (oral & written); good skills in German and/or French as local site language (oral) desired Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10058702 Aug 11, 2025 Switzerland Summary BDSS QC Bioanalytics is responsible for bioanalytical testing of Biopharmaceuticals for late-phase development projects and commercial products. Applied analytical techniques are mainly cell-based potency assays for bioactivity determination and ELISA /qPCR for the determination of process-related impurities (e.g. host-cell proteins (HCP), residual Protein A, residual DNA). About the Role We are looking for a motivated Senior QC Specialist (Lab Head) to supervise the performance of bioanalytical experiments (i.e. cell-based bioassays, ELISA and qPCR) for quality control (release, stability, and in-process control (IPC) testing) of biotech drug substances (DS) and drug products (DP) in collaboration with members of the own and cross-functional teams in a cGMP environment. Analytical method validation and transfers will be part of the position. Major Accountabilities of the role as Senior QC Specialist (Lab Head) include: Supervision of routine QC testing activities, including line unit approval of analytical records and raw data, investigations of deviations, OOE/OOS, and analytical changes Full compliance with regulatory and cGMP guidelines within the field of responsibility Support of technical project teams as analytical expert Performance of method validations (full ICH validation) and transfers, author of validation- and transfer protocols / -reports Trending and evaluation of analytical data Method lifecycle management for commercial products including method updates, post-approval changes, or troubleshooting Management and coordination of internal and external customer interfaces (e.g. testing/resource requirements, setup of service level agreements) Support in health authority inspections as subject matter expert (e.g. routine GMP inspections, pre-approval inspections) System owner of laboratory equipment and computerized systems including initial qualification and periodic maintenance/functional testing Requirements: PhD or equivalent education in Biology, Biochemistry, Chemistry, or related discipline Several years of experience in analytics / quality control in a leadership role. Experience with Biopharmaceuticals desirable Thorough knowledge of cGMP requirements Results oriented, team player and able to work with all levels of the organization Strong leadership and problem solving skills. Able to identify issues and develop business-friendly solutions in line with the overall compliance Good knowledge of instrument qualification, quality metrics Experience in audits or inspections from health authorities Very good communication and presentation skills Fluent English required (oral & written); good skills in German and/or French as local site language (oral) desired Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Verantwortlich für das Arzneimittelüberwachungsprogramm einschließlich der notwendigen Nachverfolgung, Risikobewertung und Produktverwandtwerden zu Berichten über Nebenwirkungen, Aufsicht über die Sicherheit in klinischen Studien und Post-Marketing-Programmen. Beteiligt sich an der Lösung jeglicher rechtlicher Haftung und der Einhaltung behördlicher Vorschriften. Bietet und trägt zur Trend- und Sicherheitssignalerkennung und Risikomanagementbewertung für den Lebenszyklus der Produkte bei. Bietet Sicherheitsunterstützung für die klinischen Entwicklungsteams. About the Role #LI-Hybrid Location: Basel, Switzerland Working Model: Hybrid Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible. Key Responsibilities Lead scientific projects and evaluations of safety topics across early development, full development, and marketed products Guide mechanistic investigations and integrate safety insights into cross-functional development activities Co-lead Safety Science platform meetings such as the Early Safety Hub (ESH) and Early Portfolio Safety Group (EPSG) Support preparation and scientific quality of safety board meetings, including Integrated Safety Assessment Board (ISAB) and Medical Safety Review Board (MSRB) Review and advise on mechanistic studies, Risk Management Plans, and safety signal action plans Contribute to safety training and knowledge sharing within Patient Safety as well as important clinical partner functions (Clinical Development, Translational Medicine and Translational Clinical Oncology) Collaborate with internal and external experts to advance safety science standards and practices Essential Requirements Medical degree (preferred) or PhD with relevant drug safety experience in a pharmaceutical or biotech company Peer-reviewed publications in pharmacology, clinical research or safety 3–5 years of postdoctoral or clinical experience 3–5 years of drug development experience in academia or the pharmaceutical industry Proven experience preparing clinical safety assessments and regulatory safety submissions Strong leadership in cross-functional, multicultural team environments Deep understanding of clinical trial methodology, regulatory standards, and scientific writing Fluent in English, both spoken and written Desirable Skills Understanding of an additional major language (e.g. French or German) Experience contributing to external scientific collaborations in drug safety Ready to shape the future of safety? Apply now and bring your scientific leadership to a team that’s transforming lives. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Join Novartis and make a profound impact on patient safety! As a Medical Safety Lead, you'll spearhead safety evaluations, collaborate with dynamic global teams, and craft safety strategies that not only protect patients but also drive groundbreaking medical innovation. Be a part of something extraordinary! About the Role #LI-Hybrid Primary Location: Basel, Switzerland Work Model: Hybrid Note : We are currently recruiting for various Therapeutic Areas, and your application will be considered for all relevant positions. Relocation Support: Novartis is unable to offer relocation support, please only apply if this location is accessible for you. Key Responsibilities Monitor clinical safety data, literature, and case reports to identify potential safety signals Conduct medical assessments for individual cases, including follow-ups and quality defect evaluations Perform signal detection and evaluation using aggregate and single-case data Contribute to regulatory responses and prepare safety data for health authority reviews Support safety input for core data sheets and related regulatory documentation Provide medical input for aggregate safety reports and risk management plans Collaborate with cross-functional teams on clinical safety deliverables and study documentation Offer expert evaluation on adverse event reports and guide pharmacovigilance operations Essential Requirements Master of Science / PharmD / PhD in a relevant field Fluent in spoken and written English; additional language skills are a plus Minimum 4 years of experience in drug development, including 2 years in patient safety Strong knowledge of clinical trial methodology, regulatory requirements, and scientific analysis Proven ability to interpret and present safety data clearly and effectively Experience contributing to clinical safety assessments and regulatory safety reports Desirable Medical degree (MBBS or MD) with specialization preferred Experience managing clinical safety issues Languages Fluent English (both spoken and written) is mandatory. Additional languages are an advantage. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated scientist to advance our mission to deliver transformative new therapies for patients with chronic diseases, with a special emphasis on liver diseases, in the Disease Area x (DAx) at the Novartis Biomedical Research (BR) facility located in Basel, Switzerland. In this position, you will identify and lead novel innovative therapeutic approaches to treat chronic diseases, such as liver diseases, ranging from target identification and validation to drug discovery and identification of candidate molecules towards clinical evaluation. A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In that role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. About the Role A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In this role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. Key responsibilities: Lead a group of scientists focused on preclinical activities related to the identification and validation of targets and drug candidate molecules for chronic illnesses, with a particular emphasis on liver diseases. Apply innovative in vitro/ex vivo models, which reflect human disease conditions, to identify drug candidates. Translate therapeutic concepts from preclinical models to patients and vice versa , including cutting-edge experimental approaches and application of data science tools. Strongly contribute and influence the strategic direction of liver research in DAx, stay up-to-day with latest developments in the field of liver diseases. Shape, mentor, and lead a high-performing team of scientists by fostering a collaborative environment and developing skills of team members. Navigate effectively in a matrix-based, cross-functional environment, collaborating across departments within Novartis Biomedical Research and beyond. Maintain a strong external network with academic institutions and manage external collaborations. Essential requirements: PhD/Postdoc in life science, such as cell or molecular biology or physiology. A minimum of 5 years in drug discovery for chronic diseases in an industrial setting with demonstrated expertise ranging from target identification toward clinical application. Possess an in-depth molecular understanding of physiology and disease pathophysiology, such as for liver diseases, and have expert knowledge of cell-based methods (primary cells, organotypic cultures, explants) to mimic disease conditions in vitro/ex vivo . Is highly proficient in state-of-the-art molecular, cellular and biochemical assay and profiling technologies, including – but not limited to – single-cell transcriptomics techniques. A deep understanding of data science and application of data science tools to evaluate complex datasets is highly desired. Proven leadership skills in managing and guiding teams effectively, including setting and evaluation of objectives, and advancing the development of people. Demonstrated ability to work independently and as part of a collaborative, interdisciplinary team of biologists, computational scientists, and translational research/medical scientists. Strong written and verbal communication skills, organizational skills, and excellent attention to detail. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059813 Aug 27, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated scientist to advance our mission to deliver transformative new therapies for patients with chronic diseases, with a special emphasis on liver diseases, in the Disease Area x (DAx) at the Novartis Biomedical Research (BR) facility located in Basel, Switzerland. In this position, you will identify and lead novel innovative therapeutic approaches to treat chronic diseases, such as liver diseases, ranging from target identification and validation to drug discovery and identification of candidate molecules towards clinical evaluation. A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In that role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. About the Role A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In this role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. Key responsibilities: Lead a group of scientists focused on preclinical activities related to the identification and validation of targets and drug candidate molecules for chronic illnesses, with a particular emphasis on liver diseases. Apply innovative in vitro/ex vivo models, which reflect human disease conditions, to identify drug candidates. Translate therapeutic concepts from preclinical models to patients and vice versa , including cutting-edge experimental approaches and application of data science tools. Strongly contribute and influence the strategic direction of liver research in DAx, stay up-to-day with latest developments in the field of liver diseases. Shape, mentor, and lead a high-performing team of scientists by fostering a collaborative environment and developing skills of team members. Navigate effectively in a matrix-based, cross-functional environment, collaborating across departments within Novartis Biomedical Research and beyond. Maintain a strong external network with academic institutions and manage external collaborations. Essential requirements: PhD/Postdoc in life science, such as cell or molecular biology or physiology. A minimum of 5 years in drug discovery for chronic diseases in an industrial setting with demonstrated expertise ranging from target identification toward clinical application. Possess an in-depth molecular understanding of physiology and disease pathophysiology, such as for liver diseases, and have expert knowledge of cell-based methods (primary cells, organotypic cultures, explants) to mimic disease conditions in vitro/ex vivo . Is highly proficient in state-of-the-art molecular, cellular and biochemical assay and profiling technologies, including - but not limited to - single-cell transcriptomics techniques. A deep understanding of data science and application of data science tools to evaluate complex datasets is highly desired. Proven leadership skills in managing and guiding teams effectively, including setting and evaluation of objectives, and advancing the development of people. Demonstrated ability to work independently and as part of a collaborative, interdisciplinary team of biologists, computational scientists, and translational research/medical scientists. Strong written and verbal communication skills, organizational skills, and excellent attention to detail. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. We are looking for a highly motivated, passionate researcher with a strong scientific background in radiochemistry, a curious mindset, and cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapy (RLT) . About the Role Key Responsibilities: Radioligand synthesis: Independently plan and perform the synthesis of radioligands (including LMW compounds, peptides, and protein-based vectors) using radionuclides such as Lu-177, Ga-68, and F-18, as part of a dynamic team of radiochemists in alignment with project goals. Method development: Develop, evaluate, and validate novel radiolabeling methods and formulation strategies to optimize processes. Quality control: Conduct quality control analyses of radioligands (e.g., HPLC, TLC, SEC) and ensure their readiness for preclinical in vitro and in vivo studies. Collaborative research: Collaborate effectively with multidisciplinary teams, including organic chemists, pharmacologists and cell biologists, to advance the characterization and development of radioligand therapies (RLTs) in oncology. Innovation: Explore and implement innovative technologies, including automation, to enhance efficiency in daily tasks. Radiation Safety: Adhere to radiation safety guidelines, including training, dosimetry monitoring, and proper handling and disposal of radioactive materials. Minimum Requirements - What You’ll Bring to the Role: Scientific expertise: A strong enthusiasm for hands-on experimental chemistry and radiochemistry, with the ability to interpret results critically, formulate new hypotheses, and design subsequent steps. Education: A master’s or bachelor’s degree or equivalent apprenticeship in chemistry, pharmacy, or a related field, with prior experience in radiochemistry and radiolabeling techniques (PhD is not required). Experience: At least 1-2 years of practical experience in a radiochemistry laboratory, along with proficiency in standard IT tools (e.g., E-Notebook, ChemDraw, and software-controlled lab equipment). Team-oriented approach: Passion for working in cross-disciplinary teams, exchanging scientific ideas, contributing to shared goals and learning from colleagues with diverse perspectives to advance future RLTs Mindset: Strong organizational skills, attention to detail, flexibility, and a commitment to delivering high-quality results. Technical proficiency: Familiarity with automated synthesizers for radiolabeling and purification is an advantage. Communication skills: Good written and verbal communication skills in English. Professional Growth and Development We are committed to fostering the professional growth of every team member. In this role, you will have the opportunity to develop and expand your expertise both scientifically and technically. Scientific Involvement : You will be actively involved in project teams, where you can engage intellectually, contribute your ideas, and help shape the direction of innovative projects. Technical Growth : You will have the chance to become an expert and go-to person for specific instruments, tools, or processes, making an impactful contribution to the team. As you grow in this role, you'll take on increasingly significant responsibilities, becoming a valued contributor to our team’s success. We believe in empowering our team members to thrive through collaboration, continuous learning, and meaningful challenges. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. *Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are in search of a Director/Senior Director, Health Technology Assessment (HTA) Biostatistics, with statistical expertise in HTA and Pricing and Reimbursement activities. This role offers the chance to provide statistical solutions to HTA problems. The successful candidate will work closely with International Value & Access and HEOR teams to shape ways of working for Joint Clinical Assessment in Europe to ensure high-quality deliverables. About the Role Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people’s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities – all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and welcome to where we thrive together! The Role 200+ compounds in Novartis are supported by biostatisticians in 10+ sites around the globe. Biostatisticians transform clinical data into analyses that build the basis for making innovative drugs accessible for patients. They influence decision-making in cross-functional international teams from early to late phase drug development. We are in search of a Director/Senior Director, Health Technology Assessment (HTA) Biostatistics, with statistical expertise in HTA and Pricing and Reimbursement activities. This role offers the chance to provide statistical solutions to HTA problems. The successful candidate will work closely with International Value & Access and HEOR teams to shape ways of working for Joint Clinical Assessment in Europe to ensure high-quality deliverables. Come to an industry leader where you will lead implementation of modern and innovative trial/experimental designs, statistical models, analysis and data exploration methodologies at the project level. Key Accountabilities: Accountable for strategic statistical input and influence into one or more projects (clinical development plan, integrated evidence generation strategy, publication strategy, market access strategy, pricing & reimbursement strategy) Lead implementation of efficient and innovative statistical methodology in HTA (indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.), reimbursement activities, clinical trials, and observational research to accelerate patient access considering requirements across the globe (Europe, Asia Pacific and other geographies). Lead collaborations with Health Economics and Outcome Research, Market Access, and other strategic functions to drive quantitative decision making in assigned indications/program. Plan, prioritize and oversee project level activities and ensure efficient resource management within or across franchise and effective partnership with vendors. Support responses to payer requests and/or interactions. Actively contribute to internal and external scientific interactions with decision making agencies and healthcare professionals. Responsible for all statistical work, scientific and operational, in collaboration with cross-functional and cross-regional partners. Ensure quality, timely and consistency of statistical deliverables, organizational learning, and knowledge through consistent application of processes & best practices. Support selection of external vendors and oversee them for outsourced activities Keep up to date with industry trends, advancements in HTA, and innovative statistical methodology (particularly in methods applicable to observational research area of HTA) to maintain proficiency in applying new and varied methods and to be competent in justifying methods selected. Communicate statistical findings and recommendations to non-statistical stakeholders in a clear and understandable manner. Develop and mentor biostatisticians on statistical methodologies and processes. Your experience: PhD with experience preferred or MS with experience with a degree emphasis in in Statistics, Mathematics or equivalent quantitative field Advanced knowledge of applying statistics (especially indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.) and innovative approaches in experimental design and causal inference method. Expertise in HTA, reimbursement process and regulations, including key decision drivers and review processes for key international markets and strong understanding of regulatory authority processes, and drug development. Ability to manage parallel multiple projects in different therapeutic areas Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060037 Aug 18, 2025 Switzerland Summary Our ambition is to be leaders in immunology across international markets and, one of our novel products is at the core and center being a prioritized launch for the organization. The Executive Director International, Immunology, plays a pivotal role in leading the end-to-end brand strategy, encompassing the vision, development, orchestration, implementation, and evaluation of integrated Immunology strategies across major international markets. As an enterprise leader, the ED will focus on the top three countries and Regions, driving the successful launch and growth of one of our novel products in Immunology, leading the launch preparation of the Lupus indications and supporting future LCMs. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, and Customer & Market Activation teams to drive consistent strategy development and execution. This role represents the commercial team across different instances of the organization. About the Role Location: Basel, Switzerland #LI-Hybrid Key Responsibilities International Launch Strategy: Lead the development and implementation of the launch plan for the assigned indication(s), ensuring alignment with overall asset strategy and corporate objectives. Cross-Functional Leadership: Orchestrate a global/international, cross-functional team (Medical, Regulatory, Access, Commercial, Supply, etc.) to deliver seamless launch execution. Launch Readiness: Assess and drive readiness across core and priority markets, identifying risks and enabling mitigation plans to ensure timely launch execution. Insight Integration: Leverage market research, competitive intelligence, and stakeholder feedback to refine positioning, messaging, and tactical planning. International-Local Partnership: Partner closely with regional and country teams to ensure pull-through of global strategy, providing guidance and tools to support in-market success. Milestone Tracking & Governance: Define and track critical launch milestones and KPIs; lead governance updates and ensure timely decision-making across key forums. Stakeholder Engagement: Effectively communicate the product-s vision and strategic goals to senior leaders, including the International Leadership Team (ILT), Country Presidents (CP), and regional heads. Compliance & Excellence: Uphold the highest standards of compliance and launch excellence throughout all activities. Collaborate closely with global development to influence target product profile & Integrated Evidence Plan to maximize commercialization & patient access potential for the product-snew indications and LCM in key international markets. Lead the product-sInternational Commercialization Excellence (ICE) initiatives, driving best practices in customer engagement strategies. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Essential requirements: +15 years of commercial experience across various functions in countries and above country, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful launches, with commercial leadership experience and therapeutic area (TA) leadership in core markets. Extensive commercial experience in immunology, especially working with rheumatologists. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM). Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leads with vision, builds trust, and aligns diverse stakeholders to drive long-term impact across complex environments. Empowers teams and ensures results through clear communication, cross-functional collaboration, and operational excellence. Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division International Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Commercial & General Management Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10060271 Aug 19, 2025 Switzerland Summary This team within Discovery Sciences at Novartis Biomedical Research is at the forefront of integrating AI-powered tools into the drug discovery pipeline. Through collaboration in multidisciplinary and cross-functional teams, we are driving the adoption of these technologies to advance early-stage drug discovery, including the development of wet lab workflows informed by computational (in-silico) results- and vice versa. If you thrive on turning scientific challenges into computational solutions that enhance data-driven drug discovery, we encourage you to apply today. As part of a global Data Science group, you will engage with experts in structural bioinformatics, computational biology, cheminformatics, and imaging. This position offers a unique opportunity to apply cutting-edge structure-based AI approaches-such as protein-ligand co-folding and peptide design-to generate meaningful impact through collaborative wet and dry lab work. About the Role Role Responsibilities Apply AI technologies to drive progress in drug discovery projects with a focus on protein biology, including protein-ligand co-folding and peptide design. Collaborate with wet-lab specialists (structural biologists, biophysicists, protein chemists) to move structure-informed drug discovery forward using innovative, AI-enabled strategies. Develop and adapt structure-based computational methodologies tailored to project objectives. Integrate proprietary data from protein crystallography, biomolecular NMR, cryo-EM, biophysics, and screening into predictive AI models. Leverage internal and external protein data resources to create impact in drug discovery. Candidate Profile PhD or equivalent experience in structural biology, bioinformatics, cheminformatics, molecular modeling, or a related scientific discipline. Must have direct experience with modern computational tools for protein and peptide design, as well as co-folding applications. Solid understanding of molecular recognition and protein-ligand binding energetics. Competence with machine learning frameworks such as PyTorch or TensorFlow. Proficiency in scripting languages (Python, R) and high-performance computing environments on Linux. Experience automating workflows and scripting for large-scale data processing. Ability to work effectively in fast-paced, innovative settings focused on solution-driven approaches. Strong communication skills, able to present complex findings clearly in both spoken and written formats. Desirable Qualifications Understanding of drug discovery and structure-based drug design. Experience with advanced machine learning techniques. Familiarity with relational databases and SQL. Experience utilizing AWS resources. Background in protein and peptide design. Expertise in structural biophysics methods. Experience working at the wet-dry lab interface. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Data and Digital Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: • Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area • Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents • Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders • Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) • Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. • Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: ∙ Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise ∙ Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. ∙ ≥ 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. ∙ Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process ∙ Good knowledge of oncology and experience in early clinical development preferred. ∙ Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Job Description Summary The Clinical Operations Program Head (COPH) is accountable to deliver data-driven, actionable operational and strategic insights for execution of a clinical development program and all associated trials by representing GCO at the Global Clinical Team (GCT) as well as at the Global Program Team (GPT). The COPH is accountable to plan the strategic operationalization of clinical drug development programs and trials in line with the needs of the EPTs/GPTs. This specific COPH role may be focused within Immunology, CRM or Neuroscience programs. The COPH leads the GCO sub-team to determine the GCO operational input to planning prior to any given development tollgate and to prepare the Operational Execution Plan (OEP), which is authored and owned by the COPH. The OEP incorporates both data-derived insights as well as country insights which enable informed decision-making, identify complexity, enable the generation of risk mitigation plans to reduce chances of delays, allow easier adaption of actions, and ensure transparency of the GCO operational position and the downstream delivery of program and trial milestones. To do this, the COPH owns the early viability assessments and program and trial feasibility of the planned programs and trials. During the execution of the trial (concept sheet onwards), the COPH will continue to lead the GCO sub-team to ensure the progress of the trial is in line with the OEP, to proactively deploy mitigation actions whenever necessary to ensure timely delivery of the trial as per plan. Experienced leader guiding members of the organization through the GCO organizational evolution, the evolution of new “product aligned” ways of working and of our overall culture. He / she champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. About the Role Major accountabilities: Lead operational delivery of the clinical development program and is responsible for the overall operational execution of the clinical program and related trials, as aligned with the IDP/CDP. Single GCO point of contact for assigned clinical development program and related trials. Key partner to GPCH during strategy, planning and execution stage of the program and related trials ensuring that the clinical science and strategy are consistently harmonized with an operationally feasible approach within the OEP-defined operational boundaries, so that the trials generate reliable information to answer the research questions and support decision making while protecting study participants. Leads operational delivery of the assigned program and related clinical trials and for all related strategic planning, prioritization of activities within that program and owns the early viability and feasibility assessment done by the GCO sub-teams as well as the development of operational scenarios for the execution of assigned programs and trials. Oversight and management of clinical trial budget for the assigned program and trials per OEP aligned with financial toll gates (e.g. IMB) and oversight of scope changes throughout the trial and program duration. Acts as a key partner to the GCO DU Head to use the operational insights developed with the GCO sub-team to actively shape the GDD DU strategy by driving the science of operations and GCO’s voice to ensure that the development strategy is operationally executable, thus contributing to both GCO and GDD DU mid to long term success. Is a key contact to senior leaders in GCO and beyond. Empowered to manage stakeholders, resolve conflict, and facilitate agreement. Actively monitor evolution and trends in Biopharmaceutical industry and may represent GCO and Novartis at Industry consortia. May be a member of Early Program Teams, providing an early and proactive assessment of operational viability of new clinical programs and ensuring that GCO’s assessment is correctly reflected in the overall program plans. In partnership with the GCO DU Head ensure that novel programs are reflected in the mid-long term GCO strategy and that GCO is prepared for their operationalization. The COPH champions a product oriented agile mindset, fostering a culture of experimentation combined with accountable delivery and overall high performance. Essential Requirements : Bachelors in life science/healthcare required; Advanced degree or equivalent education/degree in life sciences/ healthcare preferred (PhD/MD/ PharmD/ Masters) and 10+ years relevant experience in pharmaceutical drug development. Experience in managing associates globally and in management in a matrix organization. Proven ability to lead cross functional matrix teams applying product-oriented agile ways of working. Strong leadership, interpersonal and problem-solving skills. High resilience and ability to advocate and implement new ways of working. Extensive knowledge of clinical development processes, preferably extensive knowledge of Novartis late-stage development processes or high likelihood to develop it within 6 months after appointment. Proven ability to lead in times of organizational transformation and to lead across organizational boundaries. Strong knowledge of therapeutic area or high likelihood to develop it within 6 months after appointment. Strong matrix management skills for bridging stakeholders (business, scientific, technical) Strong relationship-building skills; can influence, negotiate with and motivate executive leadership Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Our ambition is to be leaders in immunology across international markets and, one of our novel products is at the core and center being a prioritized launch for the organization. The Executive Director International, Immunology, plays a pivotal role in leading the end-to-end brand strategy, encompassing the vision, development, orchestration, implementation, and evaluation of integrated Immunology strategies across major international markets. As an enterprise leader, the ED will focus on the top three countries and Regions, driving the successful launch and growth of one of our novel products in Immunology, leading the launch preparation of the Lupus indications and supporting future LCMs. The incumbent will collaborate closely with Global Drug Development (GDD), International Medical Affairs, Value & Access, and Customer & Market Activation teams to drive consistent strategy development and execution. This role represents the commercial team across different instances of the organization. About the Role Location: Basel, Switzerland #LI-Hybrid Key Responsibilities International Launch Strategy: Lead the development and implementation of the launch plan for the assigned indication(s), ensuring alignment with overall asset strategy and corporate objectives. Cross-Functional Leadership: Orchestrate a global/international, cross-functional team (Medical, Regulatory, Access, Commercial, Supply, etc.) to deliver seamless launch execution. Launch Readiness: Assess and drive readiness across core and priority markets, identifying risks and enabling mitigation plans to ensure timely launch execution. Insight Integration: Leverage market research, competitive intelligence, and stakeholder feedback to refine positioning, messaging, and tactical planning. International-Local Partnership: Partner closely with regional and country teams to ensure pull-through of global strategy, providing guidance and tools to support in-market success. Milestone Tracking & Governance: Define and track critical launch milestones and KPIs; lead governance updates and ensure timely decision-making across key forums. Stakeholder Engagement: Effectively communicate the product’s vision and strategic goals to senior leaders, including the International Leadership Team (ILT), Country Presidents (CP), and regional heads. Compliance & Excellence: Uphold the highest standards of compliance and launch excellence throughout all activities. Collaborate closely with global development to influence target product profile & Integrated Evidence Plan to maximize commercialization & patient access potential for the product’s new indications and LCM in key international markets. Lead the product’s International Commercialization Excellence (ICE) initiatives, driving best practices in customer engagement strategies. Foster a customer-centric mindset within the international and country teams, focusing on personalizing experiences to extend patient reach and commercial impact. Essential requirements: +15 years of commercial experience across various functions in countries and above country, demonstrating a broad and deep understanding of the commercial landscape. Proven track record of successful launches, with commercial leadership experience and therapeutic area (TA) leadership in core markets. Extensive commercial experience in immunology, especially working with rheumatologists. Experience with high-performing/high-growth brands or markets, with a clear understanding of key drivers that influence shifting customer and patient behaviors to ensure successful asset launches Proficient in translating scientific data into differentiated brand value propositions, enabling impactful launches across pre-launch through lifecycle management (LCM). Strong track record in collaborating and partnering with cross-unit, cross-functional & key markets to achieve strategic and performance targets. Leads with vision, builds trust, and aligns diverse stakeholders to drive long-term impact across complex environments. Empowers teams and ensures results through clear communication, cross-functional collaboration, and operational excellence. Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland Join our dynamic legal team as the Head of Finance Legal RoW, where you will play a pivotal role in shaping strategic decisions at the Novartis Group level. This is a unique opportunity to lead a talented team with impact— serving as a strategic legal advisor to senior leaders on Swiss and European capital markets, securities law, and corporate finance, while driving compliance and innovation in a fast-paced, global healthcare environment. About the Role Key Responsibilities Lead the Swiss Finance Legal team Provide strategic expert legal advice to, and contribute to the decision-making process of business partners, including but not limited to top and senior management, such as ECN members, Group Treasury, Global Tax, Global FRA, Global Head Investor Relations, in all aspects of financial law (e.g. legal advice relating to disclosure and reporting requirements, Swiss and European debt and equity capital markets transactions, asset management, investments and hedge funds, derivatives and treasury operations, financial structuring, capital allocation and corporate housekeeping) and Swiss company law Lead the processes for SIX filings and ad hoc disclosures coordinated at Novartis Group level Lead global, cross-divisional, cross-border and cross-functional complex transactions and regulatory projects requiring in-depth legal, finance and business knowledge Act as secretary, member and/or chair to, and attend meetings of, as needed, the boards of directors of strategically important Novartis subsidiaries and foundations, and exercise supervision, control activities and influence strategically important decision-making Ensure compliance and corporate governance of the activities of strategically important Novartis subsidiaries with applicable corporate laws and regulations and develop innovative solutions to challenges Ensure global compliance with financial regulations (e.g., EU Directives, SOX, IFRS standards and Swiss standards), including monitoring of regulatory changes and advising on implementation. Train and advise Business Partners on new legal trends, legislation and regulations in the Subject Matter Areas Instruct and supervise law firms providing advice to Novartis in the Subject Matter Areas and represent the interests of the Novartis Group in trade associations and other bodies Essential Requirements: University degree in law and admission to the Swiss bar Substantial working experience with expert level knowledge in all aspects of financial law and Swiss company law, including strong experience in transactional matters such as Swiss and European debt and equity capital markets, financing and other corporate finance related transactions Several years of experience in leading a team of lawyers Prior experience working in a top-tier law firm Excellent leadership, communication, and analytical skills paired with the ability to manage complex legal issues and provide clear, actionable advice Proficiency in English (written and spoken) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This team within Discovery Sciences at Novartis Biomedical Research is at the forefront of integrating AI-powered tools into the drug discovery pipeline. Through collaboration in multidisciplinary and cross-functional teams, we are driving the adoption of these technologies to advance early-stage drug discovery, including the development of wet lab workflows informed by computational (in-silico) results— and vice versa. If you thrive on turning scientific challenges into computational solutions that enhance data-driven drug discovery, we encourage you to apply today. As part of a global Data Science group, you will engage with experts in structural bioinformatics, computational biology, cheminformatics, and imaging. This position offers a unique opportunity to apply cutting-edge structure-based AI approaches—such as protein–ligand co-folding and peptide design—to generate meaningful impact through collaborative wet and dry lab work. About the Role Role Responsibilities Apply AI technologies to drive progress in drug discovery projects with a focus on protein biology, including protein–ligand co-folding and peptide design. Collaborate with wet-lab specialists (structural biologists, biophysicists, protein chemists) to move structure-informed drug discovery forward using innovative, AI-enabled strategies. Develop and adapt structure-based computational methodologies tailored to project objectives. Integrate proprietary data from protein crystallography, biomolecular NMR, cryo-EM, biophysics, and screening into predictive AI models. Leverage internal and external protein data resources to create impact in drug discovery. Candidate Profile PhD or equivalent experience in structural biology, bioinformatics, cheminformatics, molecular modeling, or a related scientific discipline. Must have direct experience with modern computational tools for protein and peptide design, as well as co-folding applications. Solid understanding of molecular recognition and protein-ligand binding energetics. Competence with machine learning frameworks such as PyTorch or TensorFlow. Proficiency in scripting languages (Python, R) and high-performance computing environments on Linux. Experience automating workflows and scripting for large-scale data processing. Ability to work effectively in fast-paced, innovative settings focused on solution-driven approaches. Strong communication skills, able to present complex findings clearly in both spoken and written formats. Desirable Qualifications Understanding of drug discovery and structure-based drug design. Experience with advanced machine learning techniques. Familiarity with relational databases and SQL. Experience utilizing AWS resources. Background in protein and peptide design. Expertise in structural biophysics methods. Experience working at the wet-dry lab interface. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: As a Formulation Project Leader in Oral Late Phase Development (NCE), you will lead and manage formulation and process development of Oral solid dosage forms from Lab-scale through scale-up and transfer to commercial scale in close collaboration with the Drug Product Subteam. Development activities include among others: formulation and process design and optimization, quality risk management as well as scientific writing of development documents and GMP documentation. For this position, special emphasis lies in bringing a keen interest and experience in applied data science and mechanistic modelling as tools to enable data-driven and efficient process development and scale-up. About the Role Your responsibilities will include but are not limited to: You have a passion for innovative formulations and technologies and bring experience in enabling formulation development. You understand the value and ideally bring experience of applying data-centric, computational models to guide formulation and manufacturing process development. You drive with scientific excellence the formulation development and manufacturing work of standard and enabling formulations and manufacturing processes of Oral Drug Products (NCE), supported by data-driven conclusions and mechanistic modelling. You collaborate closely with the Drug Product Sub-Team and Transfer Team members and together identify, understand and manage critical aspects concerning Drug Substance, Drug Product, Analytics, Packaging and Device. You maintain a regular exchange with key experts in e.g., Technology Focus Groups, Modelling & Simulation, Biopharmaceutics and further networks, and build their guidance into the development strategy and project plans. You author sound scientific and well-structured development documents as well as GMP documents to enable commercial manufacturing of new Drug Products. You contribute to the generation of CMC submission dossiers, support and answer Drug Product related questions of Health Authorities and Inspectors. What you’ll bring to the role: Advanced degree (minimum PhD) in relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 2 years of successful industry experience in the development of pharmaceutical formulations. Focus: Formulation and process development of standard and enabling formulations for small molecules (NCE) and scale up of manufacturing processes into oral drug products for commercialization. Knowledge of data science and data visualization, ideally experience of applying data-centric, computational models to guide formulation and manufacturing process development. Interdisciplinary thinking and interest in collaboration with other functions Broad and profound understanding of formulation development activities. Good knowledge of laboratory and/or technical tools (e.g., QbD, PAT) as well as knowledge of relevant GLP, GMP regulations and policies. Successfully demonstrated track record of creativity and problem solving in projects. Effective communication, organizational, planning and negotiation skills. Scientific and technical writing skills Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a member of the RA Data Strategy and Management Platform team, the Data Governance and Quality Capability Lead is responsible for independently driving and implementing data standards and strategies for emerging data-driven HA requirements, and relevant systems’ governance processes across all domains and functions, in support of the NVS global product portfolios to improve data maturity according to RA business objectives. The Data Governance and Quality Capability Lead is accountable to drive harmonization and continuous improvement of Data Governance related activities and initiatives in close alignment with internal and external stakeholders to improve data maturity according to RA business objectives. The Capability Lead will drive the Centralized Data Quality Management culture in Regulatory Affairs and ensure Data Quality consistency, correctness and completeness across all applicable RA systems and platforms. About the Role Major accountabilities: Lead a team to ensure alignment with organizational goals and business priorities related to Data Governance and Quality Serve as Data Governance and Quality Capability Lead for RA and as the point of contact for GDD Data team Lead RA cross-functional teams to develop data roadmap, in alignment with cross-domain Data Governance boards Accountable to create and implement data management and quality strategy Expert contributor to influence draft guidance on data standards / specifications / implementation from Health Authorities and Trade Organizations. Prepare interpretative analyses about impact on internal data and digital processes. Collaborate with Development Data Management and DDIT partners to develop and implement RA Data Governance structures (boards) and policies, ensuring involvement of Business Process Owners (BPOs) and business SMEs. Oversee vendors at the Capability level, in collaboration with IT and the External Partnerships Teams Manage Data Governance and metrics reporting on data operating model throughout the DQM lifecycle Responsible for configuration, decision making and outcome, impacting the capability, with involvement of relevant Business Process Owner(s), business SMEs and stakeholders Minimum Requirements: Bachelor’s degree, master’s; Advanced degree in life science, pharmaceutical, technology or data science preferred 8+ years of relevant industry experience Strong understanding and direct relevant experience with the Data Strategy and Management landscape of pharmaceutical regulatory affairs and Regulatory Information Management Strong network and exposure to the external environment and ability to represent company and influence in Trade organizations (e.g., EFPIA, PhRMA), International Organizations (ISO), and collaboration with regulators (e.g. ICH, EMA SPOR), or consortiums Advanced knowledge of worldwide evolving external data standards as well as drug registration and approval processes and related document format requirements and in-depth knowledge of good Regulatory compliance and intelligence practices, policies, procedures Strong understanding of regulatory requirements and structured data submissions standards and initiatives Excellent business writing, communication and effective presentation skills. Extensive experience leading meetings, driving change and cross-functional teams Strong strategic problem-solving skills and ability to innovate, analyze and navigate un-charted territory without clear precedent, ability to troubleshoot effectively, accurately and independently. Strong negotiation skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We’re a team of dedicated and smart people united by a drive to achieve together. You will drive portfolio policy for Oncology and shape an industry-leading policy strategy to create an optimal policy environment for key Novartis portfolio assets. You will lead the early portfolio scanning process with Strategy & Growth for assets and develop policy and advocacy strategies for key in-market and launch assets in alignment with a broad range of cross-functional stakeholders. Oncology will be in particular focus beyond innovative platforms. Showing deep knowledge of the pharmaceutical business model, healthcare systems, and political and economic environment, this role will proactively shape the external environment to ensure fast and sustained access to innovation and position Novartis as a trusted partner with healthcare system stakeholders. About the Role Key Responsibilities: Represent Novartis externally in TA-specific fora and trade association working groups, with an expectation of leadership and agenda setting. Develop and implement transformative policy solutions with focus on key brands and priority markets. Drive portfolio policy for the assigned TA and identifykey policy priorities alignedwith strategy and priorities for the NVS portfolio Lead early portfolioscanningprocesswith Strategy & Growth for assigned TA and develop policy strategies andsolutionsfor key in-market and launch assets in alignment with International TA. Partner with cross-functional Teams (e.g.V&A,patientadvocacy,communications, medical,healthcaresystems) to supportdesignandimplementation ofpolicystrategy for assigned TA and to prepare favorable market conditions for priority pipeline assets. Align with regions (Europe, APMA, LaCan) anddirectreporting countries (US,CN,JP)on local policyprioritiesfor TA. Articulate priority policy asks for advocacy activities inregionsand keycountriesacross the portfolio and align with regional PA Portfolio Advocacy leadsto driveregionaland localexecution ofadvocacyactivities in the TA. Provide TA-specific thought leadership and insights for GPA-led engagements supportinghealthcare system & policy change. Develop policy resources, coordinateglobal events and build coalitions within the TA and align and support implementation of deliverables with cross-functional advocacy partners. Based on a strong external network, build policy partnerships and coalitions as required. Provide policy thought leadership for Global Public Affairs led engagements that support healthcare system and policy change conducive to the Novartis portfolio. What you’ll bring to the role: ESSENTIAL CRITERIA: Extensive experience in therapeutic area-related life sciences policy, Public Affairs Policy and/or related fields, incl. policy focused patient advocacy. Established, public leadership position in Oncology related trade association working group and/or public fora, media. Experience representing the pharmaceutical industry in policy environment, with track record of measurable business impact with business and organizational awareness, enterprise perspective. Experience with designing and executing market shaping strategies across multiple geographies. Strategic sense and understanding of portfolio and commercial strategy development. Fluency in English. DESIRABLE CRITERIA: Master’s degree in relevant discipline / Advanced degree (PhD, MBA, or equivalent) in Pharmaceutical Sciences, Health Economics, Public Policy, or a related field. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As part of the Drug Product Development Scientific Office you will provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g. modeling approaches) into CMC projects in collaboration with key stakeholders. You will also support CMC teams in compiling dossiers, drive engagement with industry consortia and health authorities to enable new technologies implementation. In addition, you will propose and lead elaborating scientific solutions to development challenges. About the Role Provide strategic and scientific guidance on integrating new Biologics drug product-related technologies (such as new delivery technologies, new formulation approaches, and new development approaches, e.g., modeling approaches) into CMC projects in collaboration with key stakeholders. Promote a comprehensive approach to drug product development that focuses on the needs of patients and payers while integrating new technologies (pharmaceutical / in-silico) in line with Health Authorities expectations. Engage in industry consortia to shape regulatory environment and influence Health Authorities. Liaise with key stakeholders, including Biomedical Research, Global Program Teams, Devices and Primary Packaging, Regulatory CMC, Quality, and Commercial Manufacturing sites, to encourage them to integrate new technologies into our Biologics product while ensuring their needs for a patient-centric product are met. Support / drive interactions with health authorities through participation on briefing packages Proactively identify, lead/propose solution-oriented plans to resolve scientific drug product development challenges/barriers. Lead innovation programs as needed Minimum requirements 10+ years experience in the biopharmaceutical industry Experience in Biologics development, and specifically DP process development, understanding of drug product manufacturing process operations such as mixing, sterile filtration, and aseptic fill/finish. Experience in DP manufacturing of sterile dosage forms including frozen, liquid, and lyophilized formulations in vials and pre-filled syringes and other presentations Experience in writing regulatory modules including INDs and BLAs Relevant experience of developing and implementing strategies of patient-centered science related work Deep understanding of regulatory guidance from the FDA and EMA for development of biologic drug products, knowledge of USP and Ph. Eur. as it relates to biologics development Learning agility towards new delivery, DP process and other innovative technologies Experience of cross-functional collaboration and leading within a matrix organisation Outstanding influencing skills, leading without authority, excellent presentation and communication skills towards different internal and external stakeholders (senior management, health authorities), outstanding ability to deal with ambiguity, combined with demonstrating strong business acumen Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary As a Clinical Process Manager (CPM) in TRD GCS Clinical Packaging Operations, you will take full operational responsibility for the production of clinical trial materials, including primary packaging, labeling, and dispensing. You will act as a subject matter expert, lead process improvements, ensure compliance with GxP standards, and drive a culture of quality and performance on the shop floor. This role requires strong leadership, cross-functional collaboration, and a proactive approach to managing risks, deviations, and continuous improvement initiatives. The role is part of the team GCS Operations and reports directly to Operations Lead. #LI-Hybrid About the Role Key Responsibilities Take end-to-end responsibility for the production of primary packaged and clinical finished goods. Define, manage, and continuously improve processes related to clinical packaging, label printing, and dispensing . Provide leadership on the shop floor , ensuring daily operations meet quality, quantity, and timeline targets. Act as Subject Matter Expert (SME) in assigned areas and represent Clinical Packaging in relevant TRD and GCS activities. Drive a culture of quality and performance , using appropriate KPIs to monitor and improve operational outcomes. Identify process deficiencies and lead improvement projects to enhance efficiency and compliance. Lead deviation investigations , technical complaints, and non-Right First Time (RFT) cases; define and implement preventive and corrective actions. Ensure all process-related documentation is accurate, up to date, and compliant with internal and external guidelines. Communicate operational challenges and risks to internal and external stakeholders, adapting priorities as needed. Support and prepare for internal and external inspections , ensuring readiness and compliance. Provide training and guidance to colleagues on procedures, risks, and compliance expectations. Act as a role model for company values and behaviors, promoting a collaborative and accountable work environment. What you’ll bring to the role: Solid practical experience in chemical / pharmaceutical industry, ideally with at least 3 years of experience in a similar position within Pharma company (Near) native level of proficiency in German, fluent English Good knowledge about the Drug Development and Clinical Supply processes Excellent organization and planning skills, experience in Project management Evident knowledge of relevant regulations (e.g. GMP, HSE etc.) Demonstrated problem-solving attitude and idea generation skills Advanced communication, negotiation and interpersonal skills Experience in delivering presentations Fundamental Leadership skills (Intermediate for Associate Team Head) Ability to work in interdisciplinary teams Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Disclaimer*: Some restrictions on flexible working options may apply and will be discussed during interview if applicable You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Hiring decisions are only based on the qualification for the position, regardless of gender, ethnicity, religion, sexual orientation, age and disability. The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Adjustments for Applicants with Disabilities: The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role 1. Mitarbeit im biopharmazeutischen Herstellungsprozess im Schichtbetrieb 2. Ausführung aller zugewiesenen Tätigkeiten unter Einhaltung der gültigen GMP-, Arbeits-, Betriebs-, Umwelt- und Sicherheitsanweisungen und –richtlinien. 3. Anleitung von neuen Mitarbeitern während des on-the-job Trainings / Einarbeitungszeit. 4. Verantwortliche Durchführung einzelner Prozessstufen (Vorbereitung, Durchführung, Abschluss). 5. Ordnungsgemäße und zeitgerechte Reinigung, Vorbereitung und Sterilisierung der Produktionsgeräte und Produktionsräume 6. Durchführung von zugewiesenen Produktionsservicetätigkeiten (z.B. SAP-Buchungen, Dokumentenvorbereitung und –prüfung, Unterstützung bei Wartungsarbeiten) 7. Probenzug, Aliquotierung, Verteilung und Durchführung von ln-Prozesskontrollen 8. Durchführung des delegierten Umgebungsmonitorings für Reinräume und der delegierten Bemusterung von Reinstwasser und Reindampf 9. Organisation von Sofortmaßnahmen im Störungsfall, Melden von Auffälligkeiten an den Vorgesetzten 10. Ausführung aller zugewiesenen Tätigkeiten unter Einhaltung der GMP-, Arbeitssicherheits- und Umweltrichtlinien 11. Exzellente Dokumentation der Tätigkeiten gemäß GMP-Vorschriften 12. Einsatz für kontinuierliche Verbesserung 13. Ordnungsgemäßer Umgang mit biologischen und chemischen Substanzen in der Produktionsanlage 14. Bereitschaft zur kontinuierlichen Verbesserung und Schwachstellenanalyse 15. Teilnahme an allen für die Stelle relevanten Schulungen, Pflege der entsprechenden Trainingsnachweise 16. Voranbringen und Erhaltung eines HSE gerechten Umfelds: Melden von Beinahe-Unfällen Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland or Cambridge, MA, USA The Global Head of Modeling and Simulation (M&S) is a strategic scientific leader responsible for shaping and executing the global modeling and simulation strategy across all therapeutic areas—from early research to development. This role leads a high-performing team of expert modelers in the Pharmacokinetics (PK) Science department, driving productivity and decision-making in drug discovery and development. The Global Head will works closely with key departments within Research (including Preclinical Safety, Data and Digital, Pharmacology, Chemistry, and Biologics) and beyond (including Advanced Quantitative Sciences, Technical Research Development to ensure quantitative integration of disease, target, and compound knowledge—enhancing internal decision-making, contributing to submissions to health authorities, and increasing the probability of success for development candidates. About the Role Major accountabilities: Lead the M&S organization with responsibility for the management, allocation, and development of all M&S associates and resources and attracting and retaining top talent. Develop and champion a strategic vision to best implement and integrate the four M&S sub teams across data science, translational modeling and quantitative systems pharmacology (QSP), PBPK, and non-clinical statistics. Direct, supervise, and manage portfolio of M&S contributions to integrate relevant drug discovery and development, technical, and target / compound / disease area knowledge in the planning and execution of robust development programs and disease area strategies. In the Discovery & Preclinical Phases , M&S: M&S function to provide comprehensive support from early discovery to first-in-human clinical entry. Develops systems pharmacology platforms to guide early drug design for optimal therapeutic outcomes. Models biological targets and pathways to assess biomarkers, efficacy, and toxicity. Expands Artificial Intelligence approaches to optimize drug design across multiple therapeutic modalities and across therapy areas. Deploys statistical approaches to maximize impact of preclinical studies. In Clinical Ensure strong PBPK contributions to generate mechanistic insights on drug disposition and evaluate the impact of intrinsic and extrinsic factors on drug exposure. Expand PBPK applications beyond small molecules to support broader translational insights. Integrates preclinical and clinical biomarker and competitor data to develop mechanistic models to support FIH dose decisions. Expands the use of mechanistic models in clinical development to inform trial design and regulatory submissions through collaboration with the data and AI and pharmacometrics groups. Supports regulatory documentation and strategy. Drive the data strategy covering access, use, and storage of data used by and produced by M&S Anticipate organizational needs for M&S and strategic support based on in-depth understanding of the relevant issues and the drug development process. Identify opportunities and advocate and drive integration and implementation of innovation across the drug discovery and development continuum, such as next-generation M&S capabilities for new therapeutic modalities and emerging technologies such as digital twins & artificial intelligence. Lead infrastructure / process / scientific consulting improvement initiatives. Develop next generation M&S capabilities to serve new therapeutic modalities and emerging technologies such as digital twins and Artificial Intelligence. Provide on-boarding, training, mentoring and career development of staff, and oversee constructive and continuous performance evaluation. Member of the PK Sciences Leadership Team, contribute to overarching disciplinary and departmental strategy for PKS research and development across all Therapeutic Areas. Key performance indicators: Significant strategic and scientific impact on Biomedical Research projects and portfolio. Recognized as leading a team with best-in-class drug discovery and development M&S capabilities Develop next-generation M&S capabilities Development of staff, retention of high-performance associates, and driving a high-performance culture. Contributions to high functioning PK sciences Leadership Team Demonstrated and visible thought leadership through external visibility, reputation and shaping of industry practice. Minimum Requirements: Work Experience: Ph.D in pharmacology, biology, engineering, mathematics, statistics, computational science, or a field with significant modeling-related content (or equivalent Ph.D/MD) Skills: 15 years of relevant postdoctoral, academic, industry, or government experience with a track record as a leader and individual contributor in one or more of the following fields: Quantitative Pharmacology, Systems Pharmacology, Mechanistic Modeling, Physiologically based Pharmacokinetic Modeling, Disease Modeling, Pathway Modeling, Pharmacometrics. • Broad, integrative experience and a driven approach to the use of modeling and simulation in drug research and development. • Expert knowledge of drug discovery, drug development, and HA guidelines relevant to pre-clinical and clinical drug development. Substantial track record of identifying and leading contributions to policies that shape best practice in M&S. • Internal and external strong and established track record of establishing M&S excellence. • Excellent critical thinking and problem-solving skills. Strong record in leading global scientific improvement/change initiatives. • Significant experience in coaching, development, and influencing scientists and physicians Languages : English. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. The Global Discovery Chemistry (GDC) of the Novartis BioMedical Research (BR) department in Basel, Switzerland, is at the core of Novartis’ purpose. We are looking for a highly motivated, passionate researcher with a strong scientific background in chemistry or related life science discipline, a curious mind-set, and agility to invent innovative medicines and advance the frontiers of drug discovery. Join us and help reimagine medicine! About the Role Your responsibilities will include: • Work highly collaboratively in a multidisciplinary project team to discover and develop novel therapies across various disease areas • Design molecules addressing key project scientific questions aided by the use of cutting-edge computational tools; analyze and integrate complex data generating new design concepts and contributing to define Medicinal Chemistry project strategy • Synthesize novel derivatives using complex multi-step synthesis and/or parallel automated synthesis • Experiment in a first class laboratory infrastructure, deploy novel technologies, and collaborate with internal and external partners around the world to progress our projects • Mentor, coach, and develop a dynamic team of scientific associates • Discuss and communicate scientific results at project/group meetings, decision boards, and external conferences • Contribute to patent inventorship and scientific publications • In addition to pipeline project responsibilities, participate in global initiatives shaping the future of drug discovery at BR Minimum requirements: What you will bring to the role: • A PhD in chemistry or related life science discipline with excellent theoretical and practical experience in e.g. synthetic organic chemistry, drug discovery, chemical biology • Demonstrated track-record of initiating, leading, or being a key contributor to cutting edge research in chemistry or life sciences • A mind-set of curiosity, creativity, collaboration and openness to diverse thinking, with an enthusiasm to develop yourself and others • Ability to critically interpret results, build new experimental hypotheses, and take calculated risks and smart decisions • Passion for small molecule as well as bRo5 chemical space design; hands-on chemistry experimentation in the laboratory • Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery • Aptitude to work in a fast-paced team-oriented matrix environment • Excellent oral and written communication and strong influencing skills • Up to 5 years' experience in Medicinal Chemistry or drug discovery, in industry or academia, preferred but not required *Restrictions on flexible working arrangements may apply and will be discussed at interview if applicable Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you a highly skilled and ambitious medical professional with a passion for research? If so, we have an exceptional opportunity for you! Novartis, a world-class pharmaceutical company, is seeking a Clinical Development Medical Director - Renal to join our team in Switzerland. As a Research role, this position offers a unique chance to contribute to groundbreaking medical advancements in the field of renal medicine. About the Role Novartis is seeking a highly qualified Clinical Development Medical Director - Renal **80-100% to join our exceptional team in Switzerland or the UK. As a world-class pharmaceutical company, Novartis is dedicated to improving global health through groundbreaking research and innovative solutions. Responsibilities: Lead the clinical development activities for renal disease therapeutic area, ensuring flawless execution of clinical trials. Collaborate with cross-functional teams to design and implement clinical development plans. Provide medical expertise and guidance throughout the clinical development process. Successfully compete clinical trial protocols, investigator brochures, and informed consent forms. Determine appropriate safety monitoring and risk management strategies. Ensure compliance with all applicable regulatory and ethical guidelines. Contribute to the preparation and submission of regulatory documents. Analyze and interpret clinical trial data to support decision-making. Participate in scientific conferences and present clinical trial results. Requirements: Medical degree and experience in Nephrology or a related field. Proven experience in clinical development within the pharmaceutical or biotech industry. Strong knowledge of renal diseases and related therapies. Excellent understanding of clinical trial design and execution. Exceptional communication and interpersonal skills. Ability to work effectively in a cross-functional and multicultural environment. Strong leadership and project management abilities. Proficiency in English, both written and spoken. Novartis offers a unique opportunity for a CDMD to contribute to innovative research and make a significant impact on patients' lives. Joining our team means working with individuals who demonstrate exceptional problem-solving skills and a dedication to collaborative work in a dynamic and driven environment. At Novartis we are committed to fostering diversity and inclusion. We are an equal opportunity employer (EOE) and value the contributions of individuals from all backgrounds. We strive to provide a work environment that promotes fairness, respect, and equal opportunities for growth and development. We also understand the importance of reasonable accommodations and adjustments for individuals with disabilities. If you require any accommodations or adjustments throughout the application process, please let us know, and we will ensure that your needs are met. Join a leading organization committed to revolutionizing healthcare through advanced research and inventive solutions. Apply today and contribute to our impactful work! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are looking for a currently enrolled Master student and can offer the rare opportunity to write a Master's thesis in our Data Science and Analytics Department. The task in a nutshell: Define the Data architecture of a solution elaborated in a project leveraging existing patterns. About the Role Data Architect - Internship We are looking for a Data Architect Intern to join our project team. The ideal candidate will have a strong understanding of data flow diagrams, data modelling, and data dictionaries. They will be responsible for designing consistent and efficient storage, integration, and access to data across the development process. Preferred Start Date : ASAP Duration : 6-12 months Key responsibilities: Design and maintain data flow diagrams, data models, and data dictionaries. Develop and implement data integration processes to combine data from multiple sources into a unified view. Establish relationships between data entities and set rules and standards for integration and interoperability. Ensure efficient data management and effective analysis/reporting to support business goals. Collaborate with various departments to ensure data architecture aligns with organizational objectives. Work Arrangement : Hybrid Minimum Requirements: Education : Currently enrolled in a Master's Degree in Computer Science, Information Technology, or a related field. Experience/Professional Requirements : Proven experience in data architecture, data modelling, and data integration processes. Desirable Requirements : Experience with data governance and metadata management. Familiarity with data storage solutions and data management tools Skills: Business Architecture. (Relito, Immuta) Enterprise Architecture. (Colibra) Data Quality (Ataccama) Data Governance. Solution Architecture. (databricks on AWS) Languages : Proficiency in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Novartis holds a rich development portfolio of small molecules ready to develop into innovative, patient centric, oral dosage forms. As a Drug Product Project Leader (DPPL) working on oral dosage forms, you will lead and manage formulation and manufacturing activities linked to pharmaceutical development for small molecules (New Chemical Entities; NCE). For this position, specific emphasis lies on bringing in-depth experience of pharmaceutical unit operations and related late-phase experience including scale-up and transfer to the commercial site. You will lead drug product teams during all stages of development with a specific focus on late clinical phases. You will be working on oral Small Molecules and in particular on enabling formulation approaches. You will use your strong communication, stakeholder management and influencing skills to effectively lead the drug product sub team and the transfer team in a matrix organization. Your expertise will facilitate the planning and execution of smart DoE and scale-up / transfer campaigns to establish robust manufacturing processes and stable drug products suitable for human trials and commercial supplies following ICH principles. About the Role Your responsibilities will include but are not limited to: You lead and manage all Drug Product (DP) related technical development activities for assigned projects and you represent DP project teams in Technical Research and Development (TRD) sub-teams based on your strong scientific and pharmaceutical development expertise. You lead, manage and support the DP and the transfer teams in line with Novartis values and behaviors. You build strong team spirit and promote knowledge exchange within and between teams. You motivate and coach team members for high performance. You formulate a sound DP project strategy incl. contingency planning and risk assessments as appropriate, involving functional experts, and you ensure alignment with Pharmaceutical Development department and other departments and functions inside and outside of TRD and 3rd parties as applicable. You ensure adherence to the scientific and project review process and through relevant scientific and project management governance boards You ensure creation of high quality and scientifically sound DP development documents enabling a strong CMC submission package, and act as author, reviewer or approver for development documents in accordance with operational procedures and guidelines. You contribute to the generation of registration dossiers, answer DP related questions in internal and external audits, and support Health Authority requests. What you’ll bring to the role: PhD in Pharmaceutical Sciences or relevant scientific field (e.g., Pharmaceutical Technology, Chemical Engineering). Minimum 3 years of relevant technical experience in Development of oral Pharmaceutical Drug Products with proven experience in leading project teams in a matrix organization. Strong expertise in pharmaceutical oral dosage form development, manufacturing, and scale-up for formulations for Small Molecules including enabling formulations, manufacturing and IPC technologies, and scale-up principles. An understanding of material science principles, as applied to oral dosage forms, including the impact of physico-chemical properties of API and excipients on the drug product process and quality. Experience with application of Quality by Design and Quality risk management principles and tools as well as good working knowledge of regulatory guidelines relevant to Drug Product Development, validation, risk management, testing and stability, and new drug applications, together with technical writing and presentation skills. Ideally experience in applying data science, statistics, and DoE to enhance pharmaceutical development by providing a robust framework for data analysis, experimental design, and decision-making, leading to more effective and efficient drug development processes and documentation. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Shape the TA strategy for Radioligand Therapy (RLT), delivering early commercial insights, guiding internal pipeline and external partnerships, and aligning efforts across Research, Development, Strategy & Growth and Global Commercial teams #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the RLT TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, RLT (isotopes, radiobiology, dosimetry, etc.) and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs - To do this effectively, in-market experience is essential. Analyse reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable Proficiency in English required – spoken & written, other languages is an asset. Deep knowledge of Oncology, including multiple tumor types (or track record to acquire required TA expertise effectively and rapidly) Experience with RLT or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). Significant Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analysing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060494 Aug 21, 2025 Switzerland Summary Shape the TA strategy for Radioligand Therapy (RLT), delivering early commercial insights, guiding internal pipeline and external partnerships, and aligning efforts across Research, Development, Strategy & Growth and Global Commercial teams #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the RLT TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, RLT (isotopes, radiobiology, dosimetry, etc.) and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs - To do this effectively, in-market experience is essential. Analyse reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable Proficiency in English required - spoken & written, other languages is an asset. Deep knowledge of Oncology, including multiple tumor types (or track record to acquire required TA expertise effectively and rapidly) Experience with RLT or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). Significant Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analysing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Strategy & Growth Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area BD&L & Strategic Planning Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Bringing life-changing medicines to millions of people, Novartis sits at the intersection of cutting-edge medical science and innovative digital technology. As a global company, the resources and opportunities for growth and development are plentiful including global and local cross functional careers, a diverse learning suite of thousands of programs & an in-house marketplace for rotations & project work. With strong medicines pipeline our current transformation will not just deliver growth for our business but continue to allow us to bring innovative medicines to patients quickly. The Global Clinical Imaging and Analytics Head will coordinate and lead the application of different imaging strategies to support our portfolio of innovative medicines spanning across oncology, cardiovascular, renal, immunology, and neuroscience. Will coordinate with cross-divisional multidisciplinary teams spanning clinical, data science and commercial functions to discover, develop, evaluate and implement innovative AI/ML derived imaging biomarkers/endpoint strategies across the Novartis portfolio. This role will collaborate extensively with internal and external stakeholders to access/leverage medical imaging data/platforms and build a Novartis high value portfolio and reputation in the fields of imaging technology and clinical radiology. About the Role Major accountabilities: Develop fit for purpose clinical imaging strategies/technologies for our clinical trials and ensure high quality training at clinical sites and to data acquisition Develop and lead unique Novartis strategies for mining internal and external medical image and device data to support innovative biomarker discovery, development and implementation in drug development across multiple therapeutic areas Leverage diverse knowledge and skillsets to fully integrate and effectively communicate with clinicians, epidemiologists, data scientists, imaging experts and software engineers to meaningfully advance translational research efforts, including integration into disease animal models and other “omics/phe-nomics” data sets, where appropriate, across multiple therapeutic areas Lead AI/Machine learning approaches to develop novel structural and functional biomarkers/endpoints from medical imaging and device data to enable better quantitation of common clinical parameters or improve diagnostics, sub-classify diseases and enable predictive patient risk/stratification Lead and partner to enable impact of data science derived imaging biomarker approaches in the early drug development portfolio for “Proof of Concept/Proof of Mechanism” with Translational Medicine across multiple therapeutic areas Partner and serve as a leadership team member with NVS data platform groups e.g. DATA42/Data Sciences and AI, to clarify the landscape of clinical needs, challenges and the scope of imaging/DICOM data available to enable new analytic approaches with existing radiology software suites as well as de novo deep learning models at the voxel level Collaborate with internal stakeholders to support the advancement of imaging data repositories and data collection technologies such that the data are of maximal value to NVS systems and processes. Shape NVS policies on imaging data storage, aggregation, harmonization, retention and application so that it is well positioned to benefit NVS now and in the future Lead collaborations with internal stakeholders across NVS e.g. Biomedical Research/Development - clinical, data sciences, Chief Digital Office/AI Innovation Center/DATA42 to fully leverage enterprise imaging and data science expertise, optimize our portfolio value and drive innovation Team management and responsibility for a group of 10-30 Associates Key performance indicators: Lead the discovery, advancement and qualification of specific imaging based biomarkers/endpoints which can deliver personalized medicine approaches across Novartis portfolio spanning over research and development programs, providing the highest value added medicines Enable BR and Dev to test biological and therapeutic hypotheses in clinical development, resulting in clear proof of concept/mechanism readouts, health authority endorsements, and commercial differentiation, potentially helping in successful program acceleration. Recognized internally and externally through publications, leading global strategies/teams and consortium impacts as a subject matter expert/leader for NVS Adherence to Novartis Values and Behaviors, especially innovation and collaboration Education/Experience : PhD/MD, preferably MD, board certified radiologist with clinical research and data sciences training and/or certification, as well as a deep understanding of clinical epidemiology that can be applied to questions of diagnosis, biomarker development and treatment monitoring 5 to 10 years professional/industry experience Extensive Clinical and Diagnostic Radiology experience in areas such as Cardiovascular, Immunology, Neurology, Renal and Oncology Experienced in medical multi-modality imaging platforms such as MRI, CT, PET and ultrasound Substantial impactful global experience developing and leading multidisciplinary matrix teams across Pharma/biotech (clinical research through healthcare applications), academic institutions, and commercial business functions Demonstrated technical and scientific expertise in multiple areas for development of innovative biomarker solutions Well-developed interpersonal skills with good presence and ability to influence and negotiate with senior leadership, experienced presenter and communicator Recognized internally and externally by key stakeholders; in depth understanding of external environment/trends; develops a strong professional network Languages: Fluent in oral and written English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards its-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated and experienced Principal Scientist II/Senior Principal Scientist to be a leader in our RNAi drug discovery efforts at Novartis' Biomedical Research labs at our Basel site. This is an exciting opportunity to be at the cutting-edge of xRNA therapeutics, and to play a strategic role in driving the development of RNAi-based therapies, leveraging a deep understanding of RNAi biology and chemistry to advance programs from concept to clinical development, in areas such as Liver, Renal and Metabolic diseases. The ideal candidate will combine exceptional scientific expertise with strong leadership and collaborative skills to contribute to our mission of delivering transformative therapies to patients. About the Role Your responsibilities will include: Lead and mentor a team of highly skilled molecular biology scientists at the Basel site, focusing on the design, screening, and characterization of RNAi-based therapies. Design, plan, and oversee siRNA cell-based screening activities, including assay development and optimization, with a focus on implementation of high throughput automation. Perform end-to-end RNA-Seq NGS experiments to assess off-target risks, including library preparation, sequencing, and data analysis. Expand research space for off-target assessment to advance safe siRNA therapeutics to clinic Define mid- and long-term goals, establish action plans, and implement strategies for the local xRNA team in alignment with the global xRNA and Biologics Research Center strategy. Co-lead RNAi drug discovery and development programs in collaboration with Global Discovery Chemistry and Disease Areas (DA) teams. Partner with downstream development colleagues to progress RNA lead candidates toward full development. Coordinate and align activities with other Global Biologics Research Center teams and functional groups . Collaborate with DA partners to identify unmet medical needs and enable the development of novel therapeutic solutions. Represent the xRNA team on cross-functional project teams, driving the advancement of siRNA programs through the development pipeline. Provide innovative solutions to scientific challenges and lead troubleshooting efforts. Provide supervision in the laboratory setting and talent development opportunities Minimum requirements: What you will bring to the role Ph.D. in a relevant scientific discipline, including genomics, molecular biology & biochemistry with a minimum of 5 years of experience in RNAi/oligonucleotide drug discovery, recognized as an expert in the field both internally and externally. Proven experience in RNAi drug discovery, including RNAi design, screening, and characterization. Comprehensive knowledge of RNAi chemistry and biology, with a focus on lead optimization of therapeutic candidates. Strong genomics expertise, including hands-on experience with RNA-Seq experiments, from library preparation to data processing and analysis. A demonstrated track record of success, as evidenced by high-quality publications and patents. Highly collaborative mindset, combined with strong communication skills, creativity, and the ability to manage multiple projects in a fast-paced environment. Excellent oral and written communication skills. Experience with extrahepatic targeting of RNAi is preferred. Expertise in lab automation is highly desirable. If you are passionate about leading cutting-edge research, thrive in a collaborative and innovative environment, and are eager to make an impact in delivering RNAi-based therapies to patients, we encourage you to apply. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Expert to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Expert with experience in Oligonucleotide analytics. About the Role Major accountabilities: You will help leading analytical activities within a Technical CMC project team (e.g., help to define control and specification setting strategies for Drug substances and Drug products, method development, validation, stability, and release testing) You provide valuable input to the analytical CMC documents and support regulatory submissions. Manage interactions and contribute to a high level of collaboration with internal and external stakeholders. Write of analytical source documents (e.g Analytical methods, Specifications, Validation reports, Stability reports) Lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. You will be responsible to evaluate and implement new analytical methodologies with the aim of bringing the lab at the forefront of Oligonucleotide analytics. You will be responsible for writing and reviewing analytical documentations with a high focus on quality, data integrity and timelines. You will drive, lead, and manage analytical activities including impurity profiling related to the analytical development of Oligonucleotides (e. g. method development, validation, stability, and release testing). Provide scientific guidance to the cross-functional and global project teams and thereby scientifically driving our exciting Oligonucleotide portfolio. Display a collaborative and inspired attitude within the Oligonucleotide lab, project teams and stakeholders is key. What you’ll bring to the role: Desirable: PhD in analytical chemistry or equivalent and a minimum 3 years’ experience in the pharmaceutical industry in analytical development, preferably in development of sterile parenteral products. Strong expertise in the field of oligonucleotide analytics. Profound knowledge in analytical separation techniques such as liquid chromatography (RP, IEX and HILIC) is a must. Experience in method development and troubleshooting. Experience in developing control strategies. Profound expertise in Mass Spectrometry (ranging from mass confirmation to actual quantitative analysis of impurities and sequencing) is a plus. Proven leadership in guiding and mentoring colleagues GMP experience and qualification expertise in a GMP environment are assets. Strong coordination skills, collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus Eager to develop new methods and assess new analytical techniques. High level of intrinsic motivation, excellent collaborative spirit and agility are key elements for our success. Analyse and interpret complex situations, provide detailed directions for analytical approaches Languages : English. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Your main responsibilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g. xRNAs) In your role, you will be leading an analytical subteam and preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaborate with internal and external stakeholders of drug development and coaching of analytical experts. You lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. Educational background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years’ experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus. Proven knowledge in Early or late phase parenteral development and filings Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. Collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus and experience in a cGMP environment. High level and intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is a key element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Good scientific/technical writing skills. Good understating on how to use novel digital tools to become more productive in a global project management environment. Proven leadership in guiding and coaching colleagues Excellent communication and role model skills Fluent in English (oral and writing), German/ French a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary LOCATION: Basel, Switzerland or East Hanover, NJ United States ROLE TYPE: Hybrid working, #LI-Hybrid The Global Medical Affairs Executive Director Remibrutinib acts as enterprise medical voice for Remibrutinib and the associated indications/disease areas across the full lifecycle. They will lead the Global Medical Affairs asset/ disease area team, chair the cross-functional Program Medical Affairs team PMAT (incl. Scientific Communications (SciComs), Real World Evidence (RWE), International (Int'l) and US Medical Affairs (MA)) and represents it at Global Program Team (GPT). They will also be responsible for the medical strategy and tactical execution, ensuring the US and Int'l medical perspective is reflected. About the Role Major Responsibilities: Responsible for the creation, update & execution of the Integrated Evidence Plans (IEP) of Remibrutinib across the indications Remibrutinib is developed in, ensuring the right evidence is available at the right time to enable access and clinical adoption. Will act as a strategic partner to and close collaborator with Biomedical Research, Development, International Medical Affairs, US Medical Affairs, Strategy & Growth and Intl & US Commercial. Skills and capabilities: 8+ years in Pharmaceutical Industry experience in Medical Affairs and/or Clinical Development, incl. global experience. Significant experience and expertise in evidence generation activities, such as interventional or non-interventional studies and RWE projects. Significant experience and expertise in the full range of medical affairs tactics with a deep understanding of health care systems and key external stakeholders such as Healthcare professionals (HCP), payers, medical societies and guideline committees. Understands unmet medical needs, generates the right evidence to effectively address them, uses innovative, multichannel communication formats for effective evidence dissemination. Strong external network within the indication space, credibility as peer expert with external stakeholders. Strategic mindset and able to establish credibility and influence across a range of diverse stakeholders in a matrix organization to drive change. A highly self-aware and inspiring leader who effectively leads large diverse teams (PMATs) in a complex matrix, demonstrating strong influencing skills. Equipped with strong collaboration and negotiation skills, the GMA ED constructively resolves conflicts and removes barriers that get in the way of delivering results. Languages : Strong English language skills are essential as are strong communication skills to deliver clear, targeted, and scientifically sound presentations to diverse internal, including senior management and external audiences. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you an Analytical Expert who can demonstrate creativity in the field of analytical science and technology and with an interest in analytical lifecycle management.? We are looking for an expert who can support not only our current and but also future analytical control strategies for new chemical entities ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Main responsibilities: Analytical expert supporting launch and lifecycle management of projects in collaboration with the analytical project lead and multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Good understanding of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with internal and external stakeholders (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders, colleagues and third parties) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060112 Aug 19, 2025 Switzerland Summary Are you an Analytical Expert who can demonstrate creativity in the field of analytical science and technology and with an interest in analytical lifecycle management.? We are looking for an expert who can support not only our current and but also future analytical control strategies for new chemical entities ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Main responsibilities: Analytical expert supporting launch and lifecycle management of projects in collaboration with the analytical project lead and multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Good understanding of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with internal and external stakeholders (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders, colleagues and third parties) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Scientific Data & Products (SDP) group in Research Informatics (RX) is driven to maximize the impact and value to BR of software and data. We deliver powerful, functional, beautiful, and integrated software solutions that create a frictionless user experience. Our organization is here to build and apply excellence in product and data management to further Novartis drug discovery. About the Role The Data Management group in Research Informatics (RX) is seeking a visionary and technically skilled Data Architect to lead the design and implementation of enterprise-scale data architectures. This role is pivotal in ensuring that biomedical research data is AI-ready, accessible, and interoperable across scientific domains. The focus is on designing robust data architectures, technical stacks, and APIs that enable seamless data integration, governance, and utilization by AI models and data scientists. Major Responsibilities - Design and evolve enterprise-level data architectures that support scientific data interoperability and AI-readiness. - Define and implement technical stacks and APIs to enable secure, scalable, and performant data access. - Establish formal data architecture processes aligned with research data management policies and FAIR principles. - Collaborate with domain experts to define logical data domains, sub-domains, and critical data elements (CDEs). - Inventory and map physical data repositories to logical domains and facilitate metadata capture at data creation. - Develop conceptual and logical data models and document relationships between data objects. - Ensure alignment with scientific standards (e.g., HELM, CDISC) and enforce metadata governance. - Promote the creation of “born FAIR” data and support the publication of CDEs to foundational platforms (e.g., data lakes, warehouses). - Collaborate with IT, data engineering, and security teams to ensure compliance, automation, and operational integration. - Drive architectural improvements and standardization across scientific data workflows. ​ Essential Requirements: - 10+ years of experience in data architecture, data engineering, or software development. - 5+ years in scientific software or drug discovery environments. - Master’s degree or equivalent experience in a relevant field. - Deep expertise in designing data architectures, APIs, and technical stacks. - Experience with RDF, ontologies, cloud platforms (AWS, Google, Azure), and graph databases. - Strong understanding of laboratory data workflows and scientific data types (biology, chemistry, clinical). - Proven ability to align scientific and IT stakeholders around strategic data initiatives. This role offers a unique opportunity to shape the future of data architecture in biomedical research and to enable transformative AI-driven insights. ​ You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are 100 quantitative scientists supporting more than 80 clinical development projects in 10 therapeutic areas every day. As the Associate Director Pharmacometrics, you will drive the pharmacometric strategy for programs in multiple indications or a disease area. You will define the quantitative strategy that will be part of the Integrated Development Plans (IDP) for projects in Research and Early Development. In this role, you will perform or supervise execution of the pharmacometrics strategy in those programs with focus on implementing model-informed drug development (MIDD) approaches. You may manage a portfolio of projects at the disease area or indication level. You will set the strategy for informed decision making at early-stage project milestones, directly influencing drug development decisions with internal and external partners. About the Role Your Key Responsibilities: Provide global strategic pharmacometrics leadership for integrated development plans of medium to high complexity, based on relevant technical and disease area knowledge Lead and drive PMX contributions to integrate relevant technical and scientific knowledge in the planning and execution of robust quantitative development programs with focus on MIDD strategies Drive and coordinate the synthesis and integration of pharmacometrics information to support transition of drug development milestones / decision boards; identify alternative strategic options to mitigate risk on clinical programs Act as the PMX representative on early project teams and contribute to interactions with Health Authorities (e.g., responsible for PMX contributions to Briefing books, Investigator brochures, etc.) Proactively interact with partner line functions (pharmacologists, clinicians, statisticians, preclinical modelers, biomarker experts) on quantitative pharmacology aspects Plan, develop, execute and document PMX analyses Contribute to Integrated Evidence generation by leveraging disease progression and PKPD modeling techniques using various data sources (e.g., literature or Real-World Data); use historical data and knowledge for early benchmarking of assets Represent PMX in due-diligence teams to evaluate in-licensing opportunities Essential Requirements: Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent) with 6+ years’ experience in clinical drug development applying model-based methods using NLME methods and its application in Dose-exposure-response analysis, population PK/PD modeling, disease progression modeling and clinical trial simulation in academia and/or industry Clinical pharmacology, statistics and therapeutic knowledge in one or more disease areas Diverse experience in pharma industry on incorporation of MIDD strategies into drug development plans across all phases and answering challenging questions on dose and regimen justification, study design, safety analysis among others Track record of contributions to external whitepapers/ policy shaping best practice in pharmacometrics. Internally and externally established track record of developing/establishing pharmacometrics excellence Scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy. Track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10057260 Jul 17, 2025 Switzerland Summary We are 100 quantitative scientists supporting more than 80 clinical development projects in 10 therapeutic areas every day. As the Associate Director Pharmacometrics, you will drive the pharmacometric strategy for programs in multiple indications or a disease area. You will define the quantitative strategy that will be part of the Integrated Development Plans (IDP) for projects in Research and Early Development. In this role, you will perform or supervise execution of the pharmacometrics strategy in those programs with focus on implementing model-informed drug development (MIDD) approaches. You may manage a portfolio of projects at the disease area or indication level. You will set the strategy for informed decision making at early-stage project milestones, directly influencing drug development decisions with internal and external partners. About the Role Your Key Responsibilities: Provide global strategic pharmacometrics leadership for integrated development plans of medium to high complexity, based on relevant technical and disease area knowledge Lead and drive PMX contributions to integrate relevant technical and scientific knowledge in the planning and execution of robust quantitative development programs with focus on MIDD strategies Drive and coordinate the synthesis and integration of pharmacometrics information to support transition of drug development milestones / decision boards; identify alternative strategic options to mitigate risk on clinical programs Act as the PMX representative on early project teams and contribute to interactions with Health Authorities (e.g., responsible for PMX contributions to Briefing books, Investigator brochures, etc.) Proactively interact with partner line functions (pharmacologists, clinicians, statisticians, preclinical modelers, biomarker experts) on quantitative pharmacology aspects Plan, develop, execute and document PMX analyses Contribute to Integrated Evidence generation by leveraging disease progression and PKPD modeling techniques using various data sources (e.g., literature or Real-World Data); use historical data and knowledge for early benchmarking of assets Represent PMX in due-diligence teams to evaluate in-licensing opportunities Essential Requirements: Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent) with 6+ years- experience in clinical drug development applying model-based methods using NLME methods and its application in Dose-exposure-response analysis, population PK/PD modeling, disease progression modeling and clinical trial simulation in academia and/or industry Clinical pharmacology, statistics and therapeutic knowledge in one or more disease areas Diverse experience in pharma industry on incorporation of MIDD strategies into drug development plans across all phases and answering challenging questions on dose and regimen justification, study design, safety analysis among others Track record of contributions to external whitepapers/ policy shaping best practice in pharmacometrics. Internally and externally established track record of developing/establishing pharmacometrics excellence Scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy. Track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Job Description Summary Location: Basel, Switzerland Role Purpose: Design, plan, perform, interpret and report results of scientific experiments for the preparation and timely delivery of drug substances (DS), drug products (DP), processes and procedures within a multifunctional project team coordinated by a Project Leader. Manage technical lab/plant activities About the Role Your responsibilities include, but are not limited to: Developing efficient and scalable oligonucleotide processes for relevant projects within the Novartis portfolio, across various scales. Contributing to the Oligo team by developing and optimizing synthesis and purification methods used in process R&D. Generating and documenting reliable data to support oligonucleotide process development. Investigating diverse approaches to oligonucleotide synthesis and evaluating their potential using cutting-edge automated platforms. Ensuring the application of state-of-the-art technologies in all development activities. Utilizing laboratory resources efficiently to maximize productivity. Upholding high standards of laboratory and process safety. Co-authoring documentation required for process transfer to pilot plants. Acting as a consultant for troubleshooting during manufacturing campaigns. What you’ll bring to the role: A completed Master’s degree in Organic Chemistry is an advantage. Industrial experience with a focus on oligonucleotide synthesis. Hands-on experience in operating and maintaining state-of-the-art equipment, including oligo synthesizers, tangential flow filtration (TFF) systems, chromatography units, and lyophilizers. Advanced experience in programming methods for synthesizers and chromatography systems. Proficiency in common analytical techniques for oligonucleotides, including liquid chromatography (LC) and mass spectrometry (MS). Fluency in English. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10029829 Aug 15, 2025 Switzerland Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Part time Employment Type Regulär Shift Work No

Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director – Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis is at the forefront of medical research and bringing innovative and life changing medicines to millions of patients. Animal research is key to many of the great medical advances of today and animals play an integral part in the discovery and development of innovative, safe and life-saving medicines for patients. The Basel Head of Animal Welfare and Integrity Assurance (AW&IA) will lead, manage, and evolve the internal animal care and use program oversight for Biomedical Research Basel. About the Role Novartis upholds the highest standards and ethics of Animal Welfare and research, with steadfast commitment to the 3Rs principles (Reduction, refinement, Replacement), as well as introducing further improvements including the ‘4th R’ of Responsibility and our Biomedical Research sites all earning independent, international Gold Standard accreditation from the Association for Assessment and Accreditation of Laboratory Care (AAALAC). The Head of Animal Welfare and Integrity Assurance will ensure that all work involving research animals at Biomedical Research Basel is in compliance with Swiss laws and the Novartis Animal Welfare policies and standards. The role will include responsibilities such as liaising on behalf of Novartis Biomedical Research with regulatory authorities, accreditation bodies, and external groups and championing animal welfare and the 3Rs, as well as advocate for the critical role of animals in biomedical research. Your Responsibilities will include but not be restricted to: Lead internal oversight of the Biomedical Research Basel animal care and use program, including acting as site’s Lead Animal Welfare Officer and key contact for all in vivo users, regulators, and accreditation bodies. Direct Biomedical Research Basel AW&IA activities as Site Head to achieve efficient, consistent, compliant, and continuous improvement of animal care and use oversight operations, including: management and support of the license review and animal number reporting process post-approval monitoring program semi-annual inspections and program reviews investigation of reported animal welfare concerns/non-compliances ensure appropriate management of the Animal Welfare Body meetings as chair and all related preparation, facilitation, administration and follow-up actions serve as key contact to in vivo leadership including to the Institutional Official, Basel Pharmacology Council, and Basel Leadership Team support the development of the new animal management system Serve as named main point of contact for regulatory and accreditation needs, including both announced and unannounced inspections, communication with the Cantonal and Federal veterinary authorities, for documentation/information (e.g. lead AAALAC program description and site visits), and reporting out to agencies on applicable timelines (e.g. annual reports, ad hoc event reporting) Lead and manage direct reports in local AW&IA team, ensuring their development and appropriate time management. Act as a key contributor to the Global AW&IA team representing the Basel site to the Ethical Review Council, Global 3Rs Working Group and Global Risk Review teams Promote the 3Rs via leadership or delegated leadership of the local 3Rs Working Group including promotion of the 3Rs Awards programs and Innovation in 3Rs Granting program Together with colleagues in Public Affairs, promote openness and education about the continued need for and value of animal research through internal and external collaborations and communication, including participation in direct political stakeholder engagement. Minimum Requirements – what you will bring to the role: Education : University degree (PhD, Vet med, Med) in biology, veterinary medicine or medicine. Special knowledge in laboratory animal science and alternative methods. Authority approved study director role in Switzerland Experience in regulatory compliance and working as an Animal Welfare Officer in Switzerland, leading an IACUC or animal welfare body Experience: At least 5 years experiences in animal experimentation and leading and managing personnel in an in-vivo research environment Experienced in leading and managing a team of Direct and indirect Reports in a complex matrixed research and operations pharma industry environment Knowledge in public relations and Professional experience in communicating about and supporting advocacy efforts for the need for animal research to internal and external audiences highly desirable Experience working collaboratively with regulators and accreditation bodies Experience in supporting 3Rs (reduce, refine, replace animal studies) programs Languages: English and German fluent, proficiency in e.g. French would be of advantage. Desirable Continuous improvement skills and experience in using evidence to design and test improvements to programs and processes, including advancing AI and automation in licensing and reporting Experience in assessing animal care and use programmes requiring larger laboratory animal species, including Non-Human Primates (NHP), Pig, and Dog Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Without safe, easy-to-use, high-quality drug delivery systems our patients could not get their medicines. This is where you come in; the Device Technology Solution Center needs you as Senior Expert Engineering for the development of drug device combination products working alongside our talented, bright and diverse teams. Our Device Technology Solution Center drives the technical development of auto-injectors as well as novel drug delivery principles, e.g. drug delivery to the brain or radioligand therapy. We closely collaborate with project management, human factors engineers, packaging experts, analytical testing, production, external partners, regulatory experts and many more. The aim is to develop and/or integrate innovative drug delivery systems with drug formulation and author state-of-the-art technical documentation for health authorities and production. About the Role Your Responsibilities: Your responsibilities include, but are not limited to: Develop platforms and collaborate with cross-functional teams to deliver safe, user-friendly, and reliable products Lead and support teams in the field of assembly and injection molding for device/part design, equipment and process across from prototyping to commercial scale Create and maintain relevant Design History File (DHF) documents, ensuring high-quality device design and development Contribute to all phases of medical device development: ideation, prototyping, piloting, and manufacturing transfer Ensure components meet quality standards for clinical trials and commercial production Collaborate with external partners, including prototypers, toolmakers, and CMOs Identify root causes of issues, define and implement robust solutions Role Requirements Degree in mechanical engineering or equivalent Preferably 10 years of experience in medical device development Proficient spoken communication and excellent technical writing skills in English Proven experience in production of plastic and metal components Proven experience in assembly of plastic and metal components / sub-assemblies Proven experience in design for manufacturing and design for assembly Good knowledge in key regulations and standards (e.g. ISO 13485, ISO 23908, ISO 11608, ISO 10993, MDR, Design Controls) Ability to interact with cross functional team in matrix organization Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10055763 Jun 26, 2025 Switzerland Summary We are seeking a motivated analytical expert for biopharmaceutical production within the framework QC testing for in-process controls, raw materials and drug substance. The role involves leading current and future analytical control strategies, focusing on release testing, method validation, and method transfer for new biopharmaceutical entities. About the Role Major accountabilities: Coordinate, review and release of quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Participate in or create, review, approve registration documents Manage analytical weak points of assigned pipeline Perform deviations/OOX investigation Support troubleshooting for testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis, Bioburden and Endotoxin Lead validation and transfer activities for analytical procedures Lead qualification, maintenance, and calibration of instruments Lead LabOpex Projects Key performance indicators: Timely completion of key deliverables Prompt reporting of missed deadlines and aim for shortest possible lead times Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities continuous readiness for inspection Proactively identify and implement cost-reducing optimizations Minimum Requirements: MSc or PhD in biotechnology, analytical chemistry or related field, +3 years industry experience Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage Reliability, flexibility, resilience, and strong teamwork skills Skills: Continuous learning Dealing with ambiguity Decision making GMP Industry standards Laboratory equipment Laboratory excellence Quality Control (QC) testing Quality Control sampling Self awareness Technological expertise Languages : Fluent in English and German (spoken and written) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary "We’re a team of dedicated and smart people united by a drive to achieve together" Are you passionate about shaping the future of clinical development and making a meaningful impact in Cardiovascular medicine? In this pivotal role, you will oversee the end-to-end clinical development process for assigned programs within the Cardiovascular Therapeutic Area. Your expertise and leadership will ensure the seamless execution of clinical development plans while fostering a culture of empowerment, agility, and collaboration within a dynamic matrixed environment. If you thrive in a fast-paced, purpose-driven organization and have the skills to adapt swiftly to evolving business needs, we would love to have you on board! About the Role Major Accountabilities Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution of the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) and GPCH by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards Required Experience Essential MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area Clinical practice experience (including residency) and board certification or eligibility in disease area preferred Extensive experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. Experience of contributing to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Desirable Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. About the Role We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. This legal trainee position offers excellent opportunities to gain first-class, hands-on in-house legal experience within the stimulating, multinational environment of a leading pharmaceutical company. Duration: 6 months Start: January 1, 2026 Your responsibilities will include: • Support a diverse range of commercial matters relating to direct and indirect procurement, manufacturing, IT • Support diverse range of legal projects, e.g. contract templates, legal trainings, global legal research projects, digitalization, outsourcing, etc. • Assist with the drafting, negotiation and review of a variety of transactional, commercial and agreements • Draft legal memoranda on a wide variety of legal issues and disputes, Draft document and key position summaries • Provide legal advice to internal clients • You will be supervised and guided by a range of lawyers on different levels of the company, ensuring a great learning experience What you’ll bring to the role: Essential: • Swiss Law degree (Master of Law and Bachelor of Law has to be on Swiss Law), master's degree needs to be completed before start date • Business-level English skills (written and spoken), additional language is a plus • Interest in legal topics in a large multinational group of companies • High motivation to perform, to discover and learn new things and ability to work independently Desirable requirements: • Prior legal professional experience in a law firm, court or legal in-house department (internships etc.) would be helpful. We are also open to applicants without prior experience who have a strong interest and are motivated to learn on the job • Other professional experience in the corporate environment is a plus Please submit a cover letter that includes your motivation for the position and your availability to start in January 2026. Thank you. Why Novartis Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are seeking a motivated analytical expert for biopharmaceutical production within the framework QC testing for in-process controls, raw materials and drug substance. The role involves leading current and future analytical control strategies, focusing on release testing, method validation, and method transfer for new biopharmaceutical entities. About the Role Major accountabilities: Coordinate, review and release of quality control tests on biologics drug substances (Physicochemical testing, e.g. HPLC, Capillary Electrophoresis, UV) ensuring compliance with regulatory requirements Maintain excellent planning and collaboration with project team members (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders and colleagues) Participate in or create, review, approve registration documents Manage analytical weak points of assigned pipeline Perform deviations/OOX investigation Support troubleshooting for testing procedures and make recommendations for improvements, with a focus on HPLC and Capillary Electrophoresis, Bioburden and Endotoxin Lead validation and transfer activities for analytical procedures Lead qualification, maintenance, and calibration of instruments Lead LabOpex Projects Key performance indicators: Timely completion of key deliverables Prompt reporting of missed deadlines and aim for shortest possible lead times Consistently follow the GMP and GSU guidelines, and SOPs, ensuring no critical irregularities continuous readiness for inspection Proactively identify and implement cost-reducing optimizations Minimum Requirements: MSc or PhD in biotechnology, analytical chemistry or related field, +3 years industry experience Good IT skills (MS Office) and laboratory software like LIMS, Chromeleon, Empower are an advantage Reliability, flexibility, resilience, and strong teamwork skills Skills: Continuous learning Dealing with ambiguity Decision making GMP Industry standards Laboratory equipment Laboratory excellence Quality Control (QC) testing Quality Control sampling Self awareness Technological expertise Languages : Fluent in English and German (spoken and written) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10056282 Jul 15, 2025 Switzerland Summary "We-re a team of dedicated and smart people united by a drive to achieve together" Are you passionate about shaping the future of clinical development and making a meaningful impact in Cardiovascular medicine? In this pivotal role, you will oversee the end-to-end clinical development process for assigned programs within the Cardiovascular Therapeutic Area. Your expertise and leadership will ensure the seamless execution of clinical development plans while fostering a culture of empowerment, agility, and collaboration within a dynamic matrixed environment. If you thrive in a fast-paced, purpose-driven organization and have the skills to adapt swiftly to evolving business needs, we would love to have you on board! About the Role Major Accountabilities Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution of the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) and GPCH by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards Required Experience Essential MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area Clinical practice experience (including residency) and board certification or eligibility in disease area preferred Extensive experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. Experience of contributing to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Desirable Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams- representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Dublin (NOCC), Ireland Alternative Location 2 London (The Westworks), United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Job ID REQ-10059259 Aug 15, 2025 Switzerland Summary At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. In 2020, we reached 800 million patients with our products. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) at Novartis Biomedical Research in Basel, Switzerland, we are at the core of Novartis- purpose, designing and making new molecules for treating patients. We are looking for a highly motivated, passionate chemist with a curious mindset and cultural agility to invent innovative medicines and help advance the frontiers of drug discovery. Join us and help reimagine medicine! About the Role Your responsibilities will include but are not limited to: Plan and execute chemical syntheses of novel drug molecules (including LMW and bRo5) aided by in silico tools and facilitated by state-of-the-art synthetic methodologies and technologies (automation, miniaturization). Experiment in a first-class laboratory infrastructure and evaluate and deploy novel synthetic technologies to progress projects. Work collaboratively in a multidisciplinary project team and integrate experimental data to develop scientific hypotheses and prioritize novel molecules for synthesis to answer key project questions. Intellectual contribution to the success of project(s) e.g. design of novel compounds and synthesis routes as well as application of data analysis and digital tools. Support and coach other team members by sharing your know-how and experience. Discuss and communicate scientific results at project/group meetings. Take over responsibilities to maintain the highest levels of laboratory safety and infrastructure. Minimum Requirements What you will bring to the role: Degree from a University or Fachhochschule (BSc, MSc or Diplom) with a strong focus on synthetic organic chemistry, or education as Lab Technician / Chemielaborant (or equivalent apprenticeship) with significant further chemistry training. At least 7 years of drug discovery experience with excellent theoretical and practical knowledge in synthetic organic and medicinal chemistry. A strong passion for hands-on chemistry experimentation in the laboratory. Ability to critically interpret results, build new experimental hypotheses, take calculated risks and make smart decisions. Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery. Experience in overseeing synthesis conducted at Contract Research Organizations (CROs) is viewed as an advantage. Experience with molecules in the bRo5 chemical space such as peptides or siRNA is not a requirement but is viewed favorably. A mind-set of curiosity, creativity, collaboration and openness to diverse thinking, with an enthusiasm to develop yourself and others, along with having excellent oral and written communication skills. Aptitude to work in a fast-paced team-oriented matrix environment to collaborate within a highly dynamic team. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Global Program Clinical Head (GPCH) in CVM is the global clinical leader responsible for one or more clinical programs across indications, involving one or multiple compounds. The GPCH owns the risk benefit assessment for the program(s), and as the leader of Global Clinical Team(s) (GCT) is accountable for the design, implementation, and execution of a clinical development program(s) to support decision milestones, regulatory requirements and market access. The GCPH may contribute to disease area strategy About the Role Major accountabilities: Leads the GCT, represents Clinical Development on the Global Program Team (GPT) May serve as the Clinical Development Representative on Biomedical Research clinical/project teams to drive transition of pre-PoC (Proof of Concept) projects to Development Decision Point (DDP) May support Business Development & Licensing (BD&L) activities Post-DDP, leads the development and execution of the clinical strategy. Develops an endorsed Integrated Development Plan (IDP) in line with the Target Product Profile (TPP) which is designed for successful global regulatory approval/market access for one or multiple treatment indications and/or multiple programs Leads the creation of clinical components of key documents (e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents including maintenance of product licenses, registration dossiers, value dossiers, pharmacoeconomic dossiers) with high quality and consistency with IDP and TPP. Supports registration, market access, commercialization, and maintenance of product licenses (e.g., Core Data Sheet, Periodic Safety Update Report, clinical benefit-risk assessment for license renewals) for the compound(s) Together with Patient Safety, ensures continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance. Serves as a core member of the Safety Management Team (SMT) As the medical expert, leads interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards, patient advocacy groups), internal stakeholders (e.g., Research, Translational Medicine, Global Medical Affairs (GMA), Marketing, Health Economics & Outcomes Research), and internal decision boards. Minimum requirements: What you’ll bring to the role: MD or equivalent (preferred) PhD, or PharmD degree required 6 years professional experience with (MD or equivalent) OR 10 years (PhD or PharmD) of involvement in clinical research or drug development in an industry environment spanning clinical activities in Phases I through III/IV, including submission dossiers required Cardiovascular disease expertise, ideally experience with Cardio-Immunology or inflammasome Advanced knowledge of assigned therapeutic area required, with the capability to innovate in clinical development study designs that provide relevant evidence to decision-makers, and to interpret, discuss and present clinical trial or section program level data Thorough knowledge of Good Clinical Practice, clinical trial design, statistics, and regulatory/clinical development process required Experience with submissions and health authorities required Demonstrated ability to establish strong scientific partnership with key stakeholders Demonstrated leadership and management skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment (including remote) in pharmaceutical or biotech industry Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid As the Global Program Head, you will have critical impact of delivering innovation, which drives Novartis’ mission to embark on a journey to reimagine medicine. In this role, you will lead programs through the end-to-end development cycle to seek successful registration and market access. This includes all medical and scientific aspects of clinical trials, programs and studies from the design phase, through implementation and finalization to include scientific and medical input into the final review and sign-off of all pertinent clinical trial. About the Role Major accountabilities: Establish program strategy and execute implementation through milestones and decision points by leveraging cross-functional teams. Drives and implements short- and long-term project vision and strategy, while ensuring alignment across global functions, regions and CPOs in regard to strategy and direction. Communicate clear strategy to program team and functions and ensures that is reflected in the operation. Key contributor to development leadership team and influences direction of area of responsibility with long term approach. May be responsible for strategy at the disease area level encompassing multiple indications, spanning multiple products. Lead multidisciplinary team of functional experts focused on securing global regulatory approval, market access and optimized commercial value of the program, while ensuring quality, compliance (internal and external), within budget, and in a competitive and timely manner, utilizing both internal and external resources necessary. Leverage knowledge, experience, understanding of external stakeholders, internal team capabilities and portfolio needs to develop a compelling and innovative vision and strategy for the program. Deploys and prioritizes resources across development units. Ensures rigorous adherence to quality and compliance. Reports technical complaints, adverse events, special case scenarios related to products within established timelines and protocols. Drives talent acquisition among team members and within their sub-teams, including active selection and de-selection and performance management of the core membership of the program team. Expected travel: approximately 20% US domestic and/or international travel. Essential Requirements: PhD degree in the related discipline with 10+years of drug development experience, including experience in Global Program Teams and with dossier submission for new or supplemental indication. Deep drug development experience in cardio-renal-metabolism or related disease area. Prior exposure to and strong awareness of regulatory / market access / commercialization requirements particularly for US Clinical background relevant to the programs in the development franchise (medical training or experience in program teams). Experience in product registration and major health authority interactions. Longstanding experience of leading multidisciplinary teams. Innovative strategic attitude. Desirable Requirements: M.D. highly desirable. Clinical and or research experience in cardio-renal-metabolism Strong external network in field of cardio-renal-metabolism. Strong publication record with expertise recognized in the field of cardio-renal-metabolism or other compelling credentials relevant to cardio-renal-metabolism drug development. Experience in using AI/digital in research and or development. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Join our team at data42! The vision of data42 is to inspire collaborative groundbreaking data and AI initiatives, to reimagine drug discovery at Novartis and accelerate time to market, ultimately transforming healthcare and improving lives. We are a small team dedicated to bringing this vision to life by accelerating secondary research and data-driven decisions where we provide scientific support and data ready for analysis in a collaborative environment, leveraging a secure and governed AI-enabled platform The Semantics Technologies Associate Director will Lead data42’s implementation of Semantics and Metadata standards and be responsible of their quality across all data processing pipelines (Pre-Clinical, Clinical, Omics & RWD) from ingest to making data accessible for disease-centric multimodal analysis & investigation as well as being responsible for enabling “Data Findability” through a data FAIRification process by providing the required structured data with integrating advanced ontology management and metadata standardization (e.g., MedDRA, SDTM, ADaM, WHODrug & ISO taxonomies) enabling advanced patient cohorting & analytical functionalities. The Semantics Technologies lead will also be responsible for maintaining the data42 data catalog, designing and developing metadata management systems and shaping data42’s vision for how semantics can transform the landscape of multimodal & multidimensional data utilization in the R&D and medical continuum. About the Role Major accountabilities: Interface seamlessly with semantic experts across the company including the Biomedical Research (BR), Development (Clinical Operations & Analytics) and others. Establish and implement the multimodal data roadmap for data42 contributing to identify novel drug targets and therapeutic strategies. Apply all FAIR principles ensuring that all data assets are properly tagged, governed and aligned with business objectives and make any data understandable for data42 end users Maintain data catalog of all data assets managed across the data42 ecosystem Brings expertise and supports the implementation of the standardization of data models and reference data across all master data defined by each data assets owner. Maintain AI-enabled metadata tools to facilitate data findability and metadata management across all data assets and expose them to data42 end users. Lead and coordinate pipelines teams towards implementing data42’s vision for enabling disease-centric multimodal investigation. Coordinate closely with teams working on semantics and metadata standards across Novartis. In conjunction with a scrum master, run the team through an agile methodology ​ Experience/Professional requirements: Third level Degree qualification and 10+ years of professional experience in metadata management, semantic technologies, ontology, Artificial Intelligence (AI), and insights generation, within the pharmaceutical, biotechnology, or a related industry. In-depth knowledge of industry standardization like CDISC (SDTM, ADaM, SEND), HL7 FHIR, MedDRA, and WHODrug. Demonstrated experience in leading and implementing large-scale data projects and initiatives, particularly those involving semantic technologies, ontologies, and knowledge graphs. Proficiency in FAIR (Findable, Accessible, Interoperable, and Reusable) data principles and their application in a business/biomedical context. In-depth knowledge of Ontological authoring & engineering e.g. ontology development process, ontology life cycle, methodologies, tools and languages required for building ontologies. Knowledge of Generative AI and Large Language Models (LLM), with a focus on leveraging these technologies to transform unstructured and unharmonized data sources into insightful and actionable information. Semantic Web Technologies (Web 2.0/3.0, RDF/OWL/SKOS, SPARQL...) and their application to the biomedical domain (OBO). Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. In 2020, we reached >800 million patients with our products. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) at Novartis Biomedical Research in Basel, Switzerland, we are at the core of Novartis’ purpose, designing and making new molecules for treating patients. We are looking for a highly motivated, passionate chemist with a curious mindset and cultural agility to invent innovative medicines and help advance the frontiers of drug discovery. Join us and help reimagine medicine! About the Role Your responsibilities will include but are not limited to: Plan and execute chemical syntheses of novel drug molecules (including LMW and bRo5) aided by in silico tools and facilitated by state-of-the-art synthetic methodologies and technologies (automation, miniaturization). Experiment in a first-class laboratory infrastructure and evaluate and deploy novel synthetic technologies to progress projects. Work collaboratively in a multidisciplinary project team and integrate experimental data to develop scientific hypotheses and prioritize novel molecules for synthesis to answer key project questions. Intellectual contribution to the success of project(s) e.g. design of novel compounds and synthesis routes as well as application of data analysis and digital tools. Support and coach other team members by sharing your know-how and experience. Discuss and communicate scientific results at project/group meetings. Take over responsibilities to maintain the highest levels of laboratory safety and infrastructure. Minimum Requirements What you will bring to the role: Degree from a University or Fachhochschule (BSc, MSc or Diplom) with a strong focus on synthetic organic chemistry, or education as Lab Technician / Chemielaborant (or equivalent apprenticeship) with significant further chemistry training. At least 7 years of drug discovery experience with excellent theoretical and practical knowledge in synthetic organic and medicinal chemistry. A strong passion for hands-on chemistry experimentation in the laboratory. Ability to critically interpret results, build new experimental hypotheses, take calculated risks and make smart decisions. Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery. Experience in overseeing synthesis conducted at Contract Research Organizations (CROs) is viewed as an advantage. Experience with molecules in the bRo5 chemical space such as peptides or siRNA is not a requirement but is viewed favorably. A mind-set of curiosity, creativity, collaboration and openness to diverse thinking, with an enthusiasm to develop yourself and others, along with having excellent oral and written communication skills. Aptitude to work in a fast-paced team-oriented matrix environment to collaborate within a highly dynamic team. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten · Teilnahme an den Herstellungsprozessen · Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) · Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume · Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) · Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen · Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden · Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien · Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen · Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften · An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen · Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung · Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung · Kenntnisse über Technik und/oder Prozesse/Produkte · Teamplayer mit gutem Teamgeist · Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten · Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) · Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität · Selbstmotivation und Lernfähigkeit · Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) · Gutes GMP-Verständnis · Gute Kenntnisse in MS Office und Prozessleitsystemen · Grundlegendes technisches Verständnis/der Automatisierung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary 24! That’s the number of months that you will be spending in Chemical Operations, Switzerland enrolled in our dynamic program. We are looking for a highly motivated recent graduate to develop and improve efficiency of commercial manufacturing processes across a diverse portfolio. This program offers young talents unique insights into various areas of chemical operations in Good Manufacturing Practice (GMP) environment. This year we provide the opportunity to work at the interface of process organic and oligonucleotides chemistry including close interaction with Chemical and Analytical Development. During this program, you will be exposed to current standards in process validation, process safety and quality, process improvement within GMP, regulatory requirements and experience the dynamics of chemical manufacturing operations. You will not only be able to transfer your theoretical know-how into practice, but also to develop your soft skills and grow your internal network for your future career in the pharmaceutical industry. About the Role Your responsibilities: Your responsibilities will vary throughout the program phases and include: Application of scientific principles and concepts to chemical process development and optimization, potential innovations, and sound root cause analysis in support of research Supporting process validation activities and related production documentation, e.g., quality risk analysis / process safety risk assessments / production batch records Close interaction with process operators, analysts, and Quality Assurance. Willingness to provide expert support to routine shift operations Provide training on specific tasks within your area of knowledge and experience / Participate in scientific exchange groups Maintain excellent collaborations with our partners Willingness to learn regulatory requirements in chemistry, production, and control. What you bring to the role PhD or recent master's degree in organic chemistry/oligonucleotide interface or related disciplines (max. 12-18 months' experience) Good organic chemistry skills. Knowledge of or interest in the production and control of complex molecules (e.g., oligonucleotides) is an advantage Understanding of engineering and upscaling aspects is an advantage An excellent track record of original research. Ready to work in international and multidisciplinary teams Open-minded personality and "can-do" attitude Strong interpersonal and communication skills are required Excellent knowledge of German, an increased knowledge of English is an advantage Why consider Novartis? 769 million lives will be touched by Novartis medicines in 2020 and while we are proud of this, we know there is much more we could do to help improve and extend people's lives. We believe that new insights, perspectives, and revolutionary solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe that our potential can thrive and grow in an uncontrolled culture underpinned by integrity, curiosity, and flexibility. And we can reinvent what is possible when we boldly collaborate to tackle the world’s tough ambitiously, the world's toughest medical challenges. Because the biggest risk in life is the risk of never trying! Imagine what you could do here at Novartis! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10057489 Jul 15, 2025 Switzerland Summary 24! That-s the number of months that you will be spending in Chemical Operations, Switzerland enrolled in our dynamic program. We are looking for a highly motivated recent graduate to develop and improve efficiency of commercial manufacturing processes across a diverse portfolio. This program offers young talents unique insights into various areas of chemical operations in Good Manufacturing Practice (GMP) environment. This year we provide the opportunity to work at the interface of process organic and oligonucleotides chemistry including close interaction with Chemical and Analytical Development. During this program, you will be exposed to current standards in process validation, process safety and quality, process improvement within GMP, regulatory requirements and experience the dynamics of chemical manufacturing operations. You will not only be able to transfer your theoretical know-how into practice, but also to develop your soft skills and grow your internal network for your future career in the pharmaceutical industry. About the Role Your responsibilities: Your responsibilities will vary throughout the program phases and include: Application of scientific principles and concepts to chemical process development and optimization, potential innovations, and sound root cause analysis in support of research Supporting process validation activities and related production documentation, e.g., quality risk analysis / process safety risk assessments / production batch records Close interaction with process operators, analysts, and Quality Assurance. Willingness to provide expert support to routine shift operations Provide training on specific tasks within your area of knowledge and experience / Participate in scientific exchange groups Maintain excellent collaborations with our partners Willingness to learn regulatory requirements in chemistry, production, and control. What you bring to the role PhD or recent master's degree in organic chemistry/oligonucleotide interface or related disciplines (max. 12-18 months' experience) Good organic chemistry skills. Knowledge of or interest in the production and control of complex molecules (e.g., oligonucleotides) is an advantage Understanding of engineering and upscaling aspects is an advantage An excellent track record of original research. Ready to work in international and multidisciplinary teams Open-minded personality and "can-do" attitude Strong interpersonal and communication skills are required Excellent knowledge of German, an increased knowledge of English is an advantage Why consider Novartis? 769 million lives will be touched by Novartis medicines in 2020 and while we are proud of this, we know there is much more we could do to help improve and extend people's lives. We believe that new insights, perspectives, and revolutionary solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe that our potential can thrive and grow in an uncontrolled culture underpinned by integrity, curiosity, and flexibility. And we can reinvent what is possible when we boldly collaborate to tackle the world-s tough ambitiously, the world's toughest medical challenges. Because the biggest risk in life is the risk of never trying! Imagine what you could do here at Novartis! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary ~Shift Lead I ~Der Schichtleiter ist dafür verantwortlich, sein Team zu leiten, um die Produktionsvorgänge planmäßig in Übereinstimmung mit den HSE- und GMP-Regeln durchzuführen. ~Prozessspezialist / Anlagenspezialist ~Führen Sie zugewiesene Fertigungsaufgaben und -aktivitäten gemäß dem Produktionsplan aus, um die rechtzeitige Produktion von Produkten in der Qualität und Quantität in Übereinstimmung mit den relevanten GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. ~Dokumentationsspezialist GMP ~Der Dokumentationsspezialist GMP prüft und konsolidiert die Chargenprotokolle nach der Produktion, um sie der Qualitätssicherung gemäß den festgelegten Fristen und in der richtigen Qualität zu liefern. Der Dokumentationsspezialist GMP führt Eingaben durch und prüft Transaktionen/Deklarationen im ERP-System. About the Role Major Accountabilities ~ Schichtleitung I ~ Vertretung des Produktionsmanagements gegenüber den Teammitgliedern und Förderung der Novartis-Werte im Team ~ Line Responsibility und Shift Walkthrough ~ Engagieren und motivieren Sie das Team und liefern Sie starke Ergebnisse mit einem gestärkten Team ~ Prozessspezialist ~ Teilnahme an den Herstellungsprozessen ~ Schichtaufsicht, Teamkoordinationsplanung Und Unterstützung bei fehlender Schichtleitung oder fehlender Schichtleitung Key Performance Indicators ~Erreichen von Anlagen-KPIs ~Personalleistung: Zufriedenheitsumfrage, Ausführung von Talenten und Entwicklungsplänen, technisches Schulungsprogramm vorhanden und ausgeführt, Schulungsdaten, Gewinnung und Bindung von Talenten, Nachfolgeplan für das Fertigungsteam vorhanden und robust. ~Fristen: Einhaltung der Produktionsplanung, termingerechte Ausführung von Aufgaben Work Experience ~Operations Management und Ausführung ~Grenzüberschreitende Zusammenarbeit ~Funktionale Breite Skills ~Assemblersprache ~Kooperation ~Effizienz ~Elektronische Bauelemente ~Flexibilität ~Installationen (Computerprogramme) ~Iso (Internationale Organisation für Normung) ~Stellenbeschreibung ~Schlanke Produktion ~Fertigung (Produktion) ~Herstellungsprozess ~Nuklearmedizin ~Physik ~Produktvertrieb ~Band ~Scheduler ~Kenntnisse über GMP ~Gute Dokumentationspraxis ~Allgemeines HSE-Wissen Language Englisch Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary •Gerätebediener •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. •Service-Operator •Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität •Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You’ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. WhyNovartis? 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary In dieser Stelle sind Sie verantwortlich für die technische Verfügbarkeit und Optimierung der zugeteilten OT-Netzwerkinfrastruktur für Produktionsanlagen und Automations-Systeme. Dabei stellen Sie sicher, dass die Produktion am Standort Stein reibungslos und regelkonform nach cGxP- und HSE Richtlinien abläuft. About the Role Location : Stein, Schweiz #LI-Hybrid Ihre Aufgaben: Volle Verantwortung (Ownership) für die zugeteilten OT-Netzwerkinfrastruktur und Services, und damit verbundene Aufgaben, wie z.B. Änderungs- und Abweichungsmanagement, Dokumentation, Instandhaltung. Gewährleistung höchster Verfügbarkeit des Datentransfers inklusive der Umsetzung und Einhaltung von Cyber-Security-Massnahmen. Durchführung von Investitionsprojekten im Aufgabenbereich als Project Manager und/oder SME (Fachexperte/in). Vorantreiben der Digitalisierungs- und Innovationsstrategie mit kostengünstigen und effizienten Lösungen. Erstellung des Budgets und die Kostenkontrolle für den Betrieb der zugeteilten OT-Netzwerkinfrastruktur. Teilnahme und Unterstützung bei internen sowie externen Audits. Das bringen Sie mit: Ingenieurstudium Elektro, Automation oder Technische Informatik (FH oder HTL) oder Ähnliches. Erfahrung in Netzwerkplanung, operativer Support, Projektleitung mit Schwerpunkt Anlagen-Automation und/oder Vertikale-Integration. Fundiertes Wissen und Erfahrung im Umgang mit virtuellen Plattformen, Netzwerktechnik, Microsoft NW-Tool-Portfolio. Deutsch und Englisch Kenntnisse in Wort und Schrift. Nachgewiesene Berufspraxis im Bereich Automation und/oder ITOT vorzugsweise im Pharma- bzw. Medical Device Umfeld. Analytisches Denkvermögen, selbständiges Erarbeiten von Lösungsvorschlägen inkl. Planung und Organisation, innovatives und vernetztes Denken, kommunikatives Verhalten. Warum Novartis? Unser Ziel ist es, die Medizin neu zu erfinden, um das Leben der Menschen zu verbessern und zu verlängern. Unsere Vision ist es, das angesehenste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie können wir das erreichen? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns jeden Tag antreiben, unsere Ziele zu erreichen. Werde Teil dieser Mission und schließe dich uns an! Erfahre hier mehr: https://www.novartis.com/about/strategy/people-and-culture Was Sie erhalten: Alles, was Sie über unsere Leistungen und Prämien wissen müssen, finden Sie im Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis setzt sich für die Schaffung eines hervorragenden, integrativen Arbeitsumfelds und vielfältiger Teams ein, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Barrierefreiheit und Anpassungen: Novartis ist bestrebt, mit allen Personen zusammenzuarbeiten und angemessene Vorkehrungen für Sie zu treffen. Wenn Sie aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigen oder detailliertere Informationen über die wesentlichen Funktionen einer Position erhalten möchten, senden Sie bitte eine E-Mail an E-Mail schreiben und teilen Sie uns die Art Ihres Anliegens und Ihre Kontaktinformationen mit. Bitte geben Sie in Ihrer Nachricht die Nummer der Stellenausschreibung an. Treten Sie unserem Novartis-Netzwerk bei: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber auf dem Laufenden bleiben wollen und mehr über Novartis und unsere Karrieremöglichkeiten erfahren möchten, treten Sie hier dem Novartis-Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053045 Jul 17, 2025 Switzerland Summary In dieser Stelle sind Sie verantwortlich für die technische Verfügbarkeit und Optimierung der zugeteilten OT-Netzwerkinfrastruktur für Produktionsanlagen und Automations-Systeme. Dabei stellen Sie sicher, dass die Produktion am Standort Stein reibungslos und regelkonform nach cGxP- und HSE Richtlinien abläuft. About the Role Location : Stein, Schweiz #LI-Hybrid Ihre Aufgaben: Volle Verantwortung (Ownership) für die zugeteilten OT-Netzwerkinfrastruktur und Services, und damit verbundene Aufgaben, wie z.B. Änderungs- und Abweichungsmanagement, Dokumentation, Instandhaltung. Gewährleistung höchster Verfügbarkeit des Datentransfers inklusive der Umsetzung und Einhaltung von Cyber-Security-Massnahmen. Durchführung von Investitionsprojekten im Aufgabenbereich als Project Manager und/oder SME (Fachexperte/in). Vorantreiben der Digitalisierungs- und Innovationsstrategie mit kostengünstigen und effizienten Lösungen. Erstellung des Budgets und die Kostenkontrolle für den Betrieb der zugeteilten OT-Netzwerkinfrastruktur. Teilnahme und Unterstützung bei internen sowie externen Audits. Das bringen Sie mit: Ingenieurstudium Elektro, Automation oder Technische Informatik (FH oder HTL) oder Ähnliches. Erfahrung in Netzwerkplanung, operativer Support, Projektleitung mit Schwerpunkt Anlagen-Automation und/oder Vertikale-Integration. Fundiertes Wissen und Erfahrung im Umgang mit virtuellen Plattformen, Netzwerktechnik, Microsoft NW-Tool-Portfolio. Deutsch und Englisch Kenntnisse in Wort und Schrift. Nachgewiesene Berufspraxis im Bereich Automation und/oder ITOT vorzugsweise im Pharma- bzw. Medical Device Umfeld. Analytisches Denkvermögen, selbständiges Erarbeiten von Lösungsvorschlägen inkl. Planung und Organisation, innovatives und vernetztes Denken, kommunikatives Verhalten. Warum Novartis? Unser Ziel ist es, die Medizin neu zu erfinden, um das Leben der Menschen zu verbessern und zu verlängern. Unsere Vision ist es, das angesehenste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie können wir das erreichen? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns jeden Tag antreiben, unsere Ziele zu erreichen. Werde Teil dieser Mission und schließe dich uns an! Erfahre hier mehr: https://www.novartis.com/about/strategy/people-and-culture Was Sie erhalten: Alles, was Sie über unsere Leistungen und Prämien wissen müssen, finden Sie im Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis setzt sich für die Schaffung eines hervorragenden, integrativen Arbeitsumfelds und vielfältiger Teams ein, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Barrierefreiheit und Anpassungen: Novartis ist bestrebt, mit allen Personen zusammenzuarbeiten und angemessene Vorkehrungen für Sie zu treffen. Wenn Sie aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigen oder detailliertere Informationen über die wesentlichen Funktionen einer Position erhalten möchten, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihres Anliegens und Ihre Kontaktinformationen mit. Bitte geben Sie in Ihrer Nachricht die Nummer der Stellenausschreibung an. Treten Sie unserem Novartis-Netzwerk bei: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber auf dem Laufenden bleiben wollen und mehr über Novartis und unsere Karrieremöglichkeiten erfahren möchten, treten Sie hier dem Novartis-Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH046) Novartis Pharma Stein AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Wartungstechniker I (Cell and Gene Therapy) Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmeaktivitäten für Projekte auf Standortebene. About the Role Hauptverantwortlichkeiten Strategie & organisatorische Entwicklung Unterstützung bei Internen und externen Audits Wartung & Kalibrierung Vorbereitung von Werkzeugen, Ersatzteilen usw. für die Wartung/Kalibrierung Identifizierung von Ersatzteilen zur Wartung und Pflege der Auswahllisten Genehmigungen für Wartung/Kalibrierung/Projekte einholen​ Ausführung von Arbeitsaufträgen für Wartung/Kalibrierung gemäß Verfahrensanweisung/Verfahren Fachmännische Beaufsichtigung der Wartungs-/Kalibrierungsarbeiten Aktualisierung des Computerisierten Wartungsmanagementsystems (CWMS) nach Abschluss der Wartung/Kalibrierung Dokumentation der Ausführung der Kalibrierung​/Wartung Verwaltung des Lagers für Ersatzteile (Wareneingang, Eingangsprüfung, Lieferung an den Arbeitsbereich, Herstellung von Teilen für schnelle Reparaturen und Verbesserungen) Key Performance Indicators Wartungstechniker I Verantwortlich für die Durchführung von Wartungs- und Kalibrieraktivitäten und Inbetriebnahmearbeiten für Projekte auf Standortebene. Was Sie für die Position mitbringen: Bildungsabschluss als Elektriker oder Automatiker oder gleichwertiger Bildungsabschluss. Kalibrier Erfahrung Einschlägige Erfahrung wünschenswert, vorzugsweise in der Pharmaindustrie. Digitales & technisches Know-how. Bereitschaft für Schicht/Pikettdienst. Microsoft Office (Word, Excel etc.) Teamarbeit Kenntnisse über GMP SAP Kenntnisse Allgemeines HSE-Wissen Betriebswirtschaftliches Arbeiten Sprachen: Fließende Englisch- und Deutschkenntnisse. Skills Desired Kalibrier Erfahrung, Allgemeines HSE-Wissen, Business Networking, Effizienz, Einschließlich BIP, Employee Welfare, Fertigungsproduktivität, Gebäudetechnik, Kenntnisse über GMP, Mathematische Optimierung, Microsoft Word, Physik, Qualification, Software Troubleshooting, Team Work, Test Equipment, Total Productive Maintenance, Zusammenarbeit Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards