Novartis AG

Summary #LI-Hybrid Location: Basel, Switzerland or Dublin, Ireland. Data42 is Novartis’s data and analytics platform, that allows us to integrate different data modalities (discovery, preclinical, clinical, Real World Data (RWD)) at scale to support data-driven decision making across Novartis. We are seeking a Head of Data Engineering and Data Products to join our dynamic and innovative data and analytics team. This pivotal role is responsible for designing, building and maintaining data solutions using Palantir Foundry. In this role you will foster the use of AI/GenAI to advance the speed of high quality data delivery as well as to democratize the access to data and insights across the organization. The Head of Data Engineering and Data Products is a member of the Data42 Leadership team which comprises a Head of Data Science and Innovation, a Head of Platform as well as a Data Governance lead. In addition, this role will collaborate with key stakeholders across the Data and Digital Organization and across Novartis to ensure the rapid delivery of high quality data and data products with a team of ~50 internal and external team members. You will contribute to the overall success of Data42 as a member of the Data42 Leadership Team. This role will report directly to the Global Head of Data42. About the Role Your responsibilities include but are not limited to: Data Engineering Define the vision, lead and continue to develop our cross-functional Data Engineering and Data Products team by staying current with emerging technologies Responsible for architecting, designing, maintaining and optimizing complex data pipelines to support data exploration, operational workflows as well as advanced analytics Ensure best practices for data ingestion, processing, validation, transformation and storage Implement processes that guarantee data quality, integrity, security, compliance, and discoverability across platforms Advance the further use of automation and AI to accelerate the quality, speed and breadth of data delivery Data Products Accountable for designing, building and running scalable data product solutions using agentic workflows on Palantir Foundry to democratize data access with future needs in mind. Establish and action security and compliance policies to safeguard data access and dissemination Collaborate across the Data and Digital Organization as well as across Novartis. Support and ensure the flexible co-ordination of activities to deliver against timelines Delivery and Operations: Define and track key measurements for data systems and product success Oversee the project planning, delivery, and ongoing support for data engineering and product development Drive continuous improvement by monitoring system performance, analyze product data, and respond to feedback Essential Requirements: PhD or master’s degree in computer science or a related discipline with experience in pharma R&D with more than 10-15 yrs of experience in pharma or biotech Experience in data management, data engineering and data modelling, particularly in the design and implementation of efficient and scalable data models across different data domains with Clinical and RWD experience preferred Knowledgeable and experienced in CDISC data models/standards (i.e. SEND, SDTM, ADaM) and RWD data models/standards (i.e. OMOP) Experience with cloud platforms and cloud-based data and AI/ML solutions (Databricks, Snowflake, AWD SageMaker etc…) Strong enterprise mindset strategic thinker with a vision for data-driven decision-making from an end-to-end perspective Proven global cross-functional leadership skills including coaching and talent development, with the ability to influence stakeholders and drive organizational change within complex and ambiguous environments Excellent communication skills with proficiency in English (oral and written) Nice to have: Ideally proficient in Palantir Foundry to integrate, manage and analyze large data-sets Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Director, Medical AI & Innovation is accountable for translating key medical challenges into scalable, innovation opportunities solved by AI, including accountability for GMA AI products throughout product lifecycle. Solutions may range from off-the-shelf options (e.g., Copilot Studio) to co-development of use cases endorsed in Dev AI strategy. This role owns and advances individual GMA AI product(s) (as needed), ensuring strategic-fit and realization of business benefits. This is a dedicated functional partner for GMA AI use cases & products striving to maximise value & adoption in alignment with GMA objectives and business priorities as well as medical subject matter experts (SMEs). About the Role This role is a dynamic thought-leader for applied artificial intelligence specifically in the medical affairs domain, drawing on external insights and internal subject matter expertise in use case identification and translation of AI opportunities that drive significant impact for medical affairs. Critical to success will be an ability to develop and defend the business case value and deliver to those commitments. Value-adding products should seek to simplify and streamline medical affairs practices, in close alignment with Global Process Owners, and set Novartis GMA as the leading Medical Affairs organization in industry, systematically enabled by artificial intelligence. Key Responsibilities: Accountable for translating key medical challenges into scalable, innovation opportunities solved by AI, including accountability for GMA AI products throughout product lifecycle and co-development of use cases endorsed in Dev AI strategy. Own and advance individual GMA AI product(s), ensuring strategic-fit and realization of business benefits, in collaboration with the GMA Business Owners. Accountable for integrative planning and management of GMA AI product(s). Operate as dedicated functional partner for GMA AI use cases & products striving to maximise value & adoption in alignment with GMA objectives and business priorities, Partner, collaborate and actively align on the above with medical subject matter experts (SMEs), GMA Business Owners and technical counterparts (DDIT) Drive cross-functional alignment with close partners e.g., the AI & Innovation Product Manager (SPPO, Dev AI), ensuring continual alignment between the MA AI and Dev AI product roadmaps, and leveraging the best practices & products being scaled outside of the medical affairs domain. Engage and partner with AI and Innovation Lead (SPPO, Dev AI), including providing medical external insights/expertise, to ensure synergy with Dev AI CCE strategy and apply best practices to drive user adoption of MA AI products Establish effective relationships with business stakeholders, DDIT, change management and enabling functions to ensure robust operating model for MA AI portfolio. Promote collaborative and entrepreneurial culture and mindset. Be an agent for change and engage support for innovative ideas, methods, technologies, partnerships, and solutions to maximize value for Novartis. Requirements: Bachelor’s degree in computer science, engineering, life sciences or related field required; advanced degree (MSc, MBA etc.) preferred (or relevant business experience) Fluent English (oral and written) Minimum 8 years of working experience in technology & business solution, digital transformation, or related fields (ideally in healthcare, drug development or life sciences) Drug development and/or medical affairs and/or commercial experience (R-D-C continuum), including demonstrated innovation & transformation at functional scale Proven track-record in leading high performing, multidisciplinary teams and diverse profiles Proven ability to conceptualize, develop, and lead efforts to drive change within organizations; underpinned by excellent written and interpersonal communication skills Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: Act as Isotope Project Lead (IPL) by providing the specialist knowledge and expertise as Subject Matter Expert (SME) of radioisotope production and purification with particular focus on assessing, developing, and optimizing new technologies that support RLT products Life Cycle Management (LCM). Develop, optimize and transfer radioisotopes production and purification/separation processes. This is done in close collaboration with the relevant development centers, and Contract Manufacturing Organizations (CMOs). About the Role Major accountabilities: Manage inter functional project plan and budget using the Project Planning tool or System Identify issues and potential bottlenecks within projects and proposes options Contribute to the Radioisotope TRD-related activities. Ensure constant technological survey on the field of radioisotopes production. Apply scientific/technical expertise to identify new programs of interest for the company and support their development from early evaluation up late phase supply. Participate to development programs and activities around isotopes in adherence with global Isotope strategy and objectives within agreed timelines and budget, timely report key advancements and challenges. Identify strategic external partners for the activation of research collaboration agreement to develop new production technologies/ access to innovative isotopes. Implements strategic policies when selecting methods, techniques, and evaluation criteria for obtaining results. Establishes and assures adherence to budgets, schedules, work plans, and performance requirements. Represents area as core member in the Global Project Teams for defining global scientific strategy for development up to submission and approval in major markets of assigned product(s). Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable) Minimum Requirements: BSc. in Chemical Engineering, Pharmaceutical Technology, or equivalent scientific degree. Desirable MSc., PhD or equivalent experience. Desirable degree in Radiochemistry and strong scientific knowledge in nuclear medicine Successfully demonstrated several years (minimum of 5 years) of directly related experience in a scientific area or Ph.D. or equivalent Proven Project Leadership in all project phases Proven process understanding (Pharma, GMP, Validation and Regulatory aspects). Sound experience of data handling and applied statistics is a must. Strong understanding of risk assessment and risk management fundamentals/tools Quality-oriented with attention to detail Excellent verbal and written communication skills Excellent problem solving and decision-making skills Defining and implementing productivity improvement measures. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite ________________________________________ Be at the Forefront of Neuroscience Innovation Join Novartis and lead a world-class team driving breakthroughs in Neuroimmunology and Neuroscience. Shape the future of neuroscience by developing transformative therapies for diseases that impact millions worldwide. If you are passionate about scientific discovery, collaboration, and making a global impact, we want to hear from you. About the Role As Head of Neuroimmunology, you will design and direct preclinical strategies that have the potential to deliver blockbuster therapies and transform lives. Projects that modulate neuroimmunology targets and have the potential to treat the progression in multiple sclerosis and neurodegeneration. Neuroimmunology is a priority area for the Neuroscience franchise, and a pillar of the Neuroscience department. The Head of Neuroimmunology will deliver new projects and development candidates to the Biomedical Research pipeline which have the potential of becoming highly impactful drugs for diseases such Multiple Sclerosis, Alzheimer’s Disease, Parkinson’s disease, Frontotemporal dementia and ALS. Key Responsibilities Create, communicate and execute a collaborative vision and strategy for Neuroimmunological drug discovery and early development in focus areas including mechanisms of progression in multiple sclerosis, and other neurologic diseases including Alzheimer’s, Parkinson’s, Huntington’s disease and ALS Manage, mentor and coach a team of Senior associates, postdocs and Lab Heads delivering a portfolio of Neuroimmunology drug discovery programs, and modality agnostic development candidates for human trials (LMW, genetic medicines, biologics) Serve as the Basel site head for Neuroscience collaborating with the site heads for San Diego and Cambridge as a member of the Neuroscience leadership team, in addition to being the key leader in Basel for partner departments and functions including the Immunology Disease Area, DARe, Discovery Sciences, Discovery Chemistry and Biologics Research Build relevant state of the art in vitro and in vivo models of disease incorporating relevant immune and nervous system components, and a balanced and sustainable pipeline supporting the Novartis neuroscience strategy Build and maintain strong relationships externally, e.g. with global scientific medical research community (academia and biotech), and lead and identify relevant multi-party research alliances. Function as lead representative for BD&L efforts in scientific and strategic evaluation of neuroimmunology assets for partnering or acquisition Lead and/or contribute to ad-hoc initiatives aiming at improving Biomedical Research science Minimum Requirements PhD or MD in biomedical sciences, with post-doctoral fellowship. 15+ years of industry experience, including significant research/scientific leadership in neuroimmunology relevant research (academia or industry). Demonstrated experience in bringing multiple modalities (LMW, oligonucleotides, biologics, genetic medicines) from discovery into clinical development. Proven track record in leading multi-party, international collaborations. Major scientific accomplishments, including high-impact publications and a successful drug discovery record. Fluent in English (oral and written). German language would be advantageous. Strong coaching, mentoring, and people management skills. Experience in evaluating in-licensing opportunities and conducting due diligence as required. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Senior Scientist I, Oncology Translational Research The Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area. Within OTR, the Oncology Pathology and Biomarkers (OPB) team leverages tissue-, cell-, and soluble protein–based assays to profile target epidemiology and biology, elucidate drug mechanisms of action, and define response/resistance biomarkers, from early target discovery through Phase 3 clinical development. OPB is seeking a motivated, inquisitive scientist to design and execute imaging-driven experiments that inform clinical biomarker strategies and accelerate Novartis Oncology drug candidates. About the Role The successful candidate will generate rigorous, high-quality data to propel translational research programs. By applying automated immunohistochemistry, immunofluorescence, and quantitative image analysis, they will help identify molecular predictors of response to cancer therapies, mechanisms of resistance or persistence under treatment, and opportunities for combination strategies. Working closely with the lab head and team members, the candidate will flexibly contribute to both local and global projects and proactively share expertise across groups spanning the full Oncology portfolio, including radioligand therapeutics (RLT). Key responsibilities: Deliver high‐quality data to impact drug discovery and projects in clinical development Design and conduct experiments and procedures requiring scientific and technical knowledge of immunohistochemistry and immunofluorescence Devise new techniques around tissue-based biomarkers to advance drug development and early discovery programs Supervise the development of multiplex IHC, FIHC and ISH assays Conduct in-depth image analysis of whole slide images using established platforms Consolidate, report data and present in context as needed Efficiently manage and maintain a functional laboratory, technical equipment and reagents Stay updated on the latest developments and trends in the field of Oncology and Radioligand Therapy Role Requirements: MSc or BSc or qualified Lab Technician in Biological Sciences or other relevant discipline with minimum 2 years of histology laboratory experience Advanced/Fluent English oral and written Must have experience developing singleplex and multiplex immunohistochemistry and immunofluorescence tissue-based assays Proven experience with advanced image analysis using various software tools, including HALO Experience working with cross-functional teams and demonstrated ability to independently drive projects in a matrixed environment Knowledge of cancer signaling/biology is preferred, background in radioligand development and autoradiography is a plus · Excellent organizational and communication skills Languages : English. Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10067283 Dec 15, 2025 Switzerland Summary Senior Scientist I, Oncology Translational Research The Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area. Within OTR, the Oncology Pathology and Biomarkers (OPB) team leverages tissue-, cell-, and soluble protein-based assays to profile target epidemiology and biology, elucidate drug mechanisms of action, and define response/resistance biomarkers, from early target discovery through Phase 3 clinical development. OPB is seeking a motivated, inquisitive scientist to design and execute imaging-driven experiments that inform clinical biomarker strategies and accelerate Novartis Oncology drug candidates. About the Role The successful candidate will generate rigorous, high-quality data to propel translational research programs. By applying automated immunohistochemistry, immunofluorescence, and quantitative image analysis, they will help identify molecular predictors of response to cancer therapies, mechanisms of resistance or persistence under treatment, and opportunities for combination strategies. Working closely with the lab head and team members, the candidate will flexibly contribute to both local and global projects and proactively share expertise across groups spanning the full Oncology portfolio, including radioligand therapeutics (RLT). Key responsibilities: Deliver high-quality data to impact drug discovery and projects in clinical development Design and conduct experiments and procedures requiring scientific and technical knowledge of immunohistochemistry and immunofluorescence Devise new techniques around tissue-based biomarkers to advance drug development and early discovery programs Supervise the development of multiplex IHC, FIHC and ISH assays Conduct in-depth image analysis of whole slide images using established platforms Consolidate, report data and present in context as needed Efficiently manage and maintain a functional laboratory, technical equipment and reagents Stay updated on the latest developments and trends in the field of Oncology and Radioligand Therapy Role Requirements: MSc or BSc or qualified Lab Technician in Biological Sciences or other relevant discipline with minimum 2 years of histology laboratory experience Advanced/Fluent English oral and written Must have experience developing singleplex and multiplex immunohistochemistry and immunofluorescence tissue-based assays Proven experience with advanced image analysis using various software tools, including HALO Experience working with cross-functional teams and demonstrated ability to independently drive projects in a matrixed environment Knowledge of cancer signaling/biology is preferred, background in radioligand development and autoradiography is a plus · Excellent organizational and communication skills Languages : English. Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Research & Development Biomedical Research Switzerland Job ID REQ-10067283 Scientist - Biology Apply to Job (link is external)

Summary We are seeking a highly motivated and experienced human geneticist. This role requires strong strategic and leadership skills, as well as expertise in genetics with a proven ability to identify the causal drivers of disease. You will be adept at leveraging these approaches within an interdisciplinary team to foster innovation and discover novel targets. As the site lead for Basel, you will have the opportunity to directly and indirectly lead a small team. This position is part of the Human Genetics & Targets group within the Discovery Sciences (DSc) department in Biomedical Research (BR) at Novartis. The DSc Human Genetics & Targets team is a global group of computational and experimental scientists dedicated to validating or invalidating genetics-driven target hypotheses. The team's extensive expertise in genetics analytics, biology, and translatable models is enhanced by DSc's capabilities in AI, functional genomics, chemical biology, and more. The team collaborates with disease area specialists to not only identify disease associations but also to understand the underlying disease mechanisms and advance drug discovery projects to benefit patients in need. About the Role Your responsibilities will include, but are not limited to: Leading a small team and working within a larger genetics computational group to plan, develop, and implement human genetic strategies for drug discovery projects in alignment with department and company goals Work with interdisciplinary project teams across a variety of disease areas to deliver (fit-for-purpose) human genetics analyses for drug discovery impact Guiding the use of population scale biobanks and serving as a champion for a human genetic cohort Coaching and mentoring the next generation of genetics experts Bringing scientific curiosity and enthusiasm to make discoveries in a collaborative and team-focused environment Engaging as an insightful and proactive member of the DSc Human Genetics Data Science team to shape the strategic direction of the team and broader BR genetics efforts What you’ll bring to the role: PhD with 7+ years of post-graduate work or equivalent experience in genetics Experience analyzing and interpreting human genetics data is a must Extensive experience with the management and analysis of large biobank data is a must and experience of multiple biobanks is preferred. Strong leadership skills and experience leading computational scientists Drug discovery experience in an industry stetting is encouraged but not required Experience with additional ‘omics data (RNA sequencing, epigenetics, proteomics) and NGS data A curiosity for emerging technologies and methods Exceptional collaboration, communication and problem-solving skills, learning agility, and an interest in engaging with peers for the design and implementation of new ideas A strong publication record Fluency in Python, R, SQL and/or other relevant programming languages Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve ​ Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10066548 Nov 18, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: We are seeking a highly motivated and experienced PhD-level scientist to lead our mid/large xRNA synthesis team in Basel. This position requires extensive collaboration within a multidisciplinary environment, bridging research and development to discover and advance innovative siRNA therapies addressing significant unmet medical needs. About the Role Key Responsibilities Oversee a state-of-the-art oligonucleotide synthesis facility, managing both capital and consumables budgets efficiently. Lead and guide a team of scientists specializing in oligonucleotide synthesis and purification of oligonucleotides at millimole scale to deliver on our growing siRNA portfolio Ensure the delivery of high-quality siRNA products for both in vitro screening and in vivo evaluation within drug candidate pipelines. Collaborate with discovery xRNA existing oligonucleotide synthesis teams in Basel as well as in Cambridge Provide technical leadership to the scale-up team in the synthesis of oligonucleotides, optimize methodologies and processes to improve efficiencies Collaborate with synthetic chemists and project teams to scale up new siRNA chemistries that address critical scientific challenges and facilitate their seamless transition into development. Document and effectively communicate results and scientific insights to internal and external stakeholders through patent applications and scientific publications. Mentor and support team members by sharing technical expertise and hands-on experience within the work environment. Excellent problem solving skills and solution orientated mindset Qualifications and Requirements A PhD in synthetic chemistry focused on oligonucleotides. 2-3 years experience in the industry setting Proven practical experience in oligonucleotide solid phase synthesis and downstream processing with an expertise in a mid/large scale oligo synthesis and in process development. Demonstrated leadership abilities and experience developing scientific teams. Capacity to promote and implement innovative ideas within a global team context. Strong independent problem-solving skills. Proven collaborative attitude Proficiency in managing multiple priorities effectively while maintaining focus where necessary. Excellent verbal and written communication abilities. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Locations: Basel, Switzerland; Dublin, Ireland; Westworks, London, UK Full time Hybrid The Director, Pipeline Governance, plays a pivotal role in shaping how development projects are managed and executed across the organization. This position leads to the optimization of portfolio governance and project management processes, ensuring seamless, compliant, and efficient planning for drug development programs. By driving alignment on governance frameworks, standardizing data models, and harmonizing workflows, the Director enables clarity and consistency across functions and units. About the Role The Director Pipeline Governance champions best practices that safeguard data integrity and system reliability while fostering collaboration across functions. With a focus on innovation and operational excellence, the Director spearheads adoption and enhancement of cutting-edge planning capabilities/ systems, deliver training and change management to empower teams. This is an opportunity to influence strategic decisions and create impact by ensuring high-quality, timely, and accurate portfolio data that drives smarter, faster development outcomes. Join us and lead the transformation of governance into a true enabler of success. Key responsibilities: Drive strategic governance and continuous improvement of project and portfolio management processes and systems to ensure compliance and operational excellence. Champion best practices that ensure data integrity, process consistency, and system reliability, setting the gold standard for operational performance. Shape the future of development by aligning and harmonising workflows, data models, and systems to deliver seamless, compliant planning across global teams. Collaborate with diverse stakeholders to solve complex challenges, implement smart enhancements, and unlock new levels of organisational agility. Inspire change by leading adoption initiatives, delivering impactful training, and building capabilities that empower teams to thrive in a dynamic environment. Minimum Requirements: A graduate degree in life sciences (Master’s or equivalent); PhD or similar advanced qualification strongly preferred, with practical understanding of data governance and analytics tools as an advantage. Proven experience in leading governance and optimization of project and portfolio management processes, with strong familiarity with PPM systems, workflows, and data models. Track record of driving alignment and standardization across complex, global organizations, ensuring compliance and operational excellence in drug development or related environments. Evidence of influencing strategic decisions and leading cross-functional initiatives in matrix organizations, building trusted partnerships and delivering results without formal authority. Influence senior leadership and key decision-makers as a trusted partner, ensuring governance strategies align with bold organisational ambitions. Drive resource optimisation and proactive risk management, keeping the organisation agile, future-ready, and positioned for success. Strong capability in change management and adoption of systems, including delivering training and embedding best practices to enhance organizational performance. Ability to operate under pressure, meeting tight timelines, and engaging confidently with senior stakeholders to shape governance strategies and enable informed decision-making. Exceptional communication skills demonstrated by tailoring messages for diverse audiences, combined with curiosity and a commitment to continuous improvement and innovation. Fluent in English (oral and written). Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite Role Purpose: We are seeking a highly motivated and experienced PhD-level scientist to lead our mid/large xRNA synthesis team in Basel. This position requires extensive collaboration within a multidisciplinary environment, bridging research and development to discover and advance innovative siRNA therapies addressing significant unmet medical needs. About the Role Key Responsibilities Oversee a state-of-the-art oligonucleotide synthesis facility, managing both capital and consumables budgets efficiently. Lead and guide a team of scientists specializing in oligonucleotide synthesis and purification of oligonucleotides at millimole scale to deliver on our growing siRNA portfolio Ensure the delivery of high-quality siRNA products for both in vitro screening and in vivo evaluation within drug candidate pipelines. Collaborate with discovery xRNA existing oligonucleotide synthesis teams in Basel as well as in Cambridge Provide technical leadership to the scale-up team in the synthesis of oligonucleotides, optimize methodologies and processes to improve efficiencies Collaborate with synthetic chemists and project teams to scale up new siRNA chemistries that address critical scientific challenges and facilitate their seamless transition into development. Document and effectively communicate results and scientific insights to internal and external stakeholders through patent applications and scientific publications. Mentor and support team members by sharing technical expertise and hands-on experience within the work environment. Excellent problem solving skills and solution orientated mindset Qualifications and Requirements A PhD in synthetic chemistry focused on oligonucleotides. 2-3 years experience in the industry setting Proven practical experience in oligonucleotide solid phase synthesis and downstream processing with an expertise in a mid/large scale oligo synthesis and in process development. Demonstrated leadership abilities and experience developing scientific teams. Capacity to promote and implement innovative ideas within a global team context. Strong independent problem-solving skills. Proven collaborative attitude Proficiency in managing multiple priorities effectively while maintaining focus where necessary. Excellent verbal and written communication abilities. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Strategic Assistant will report directly to International Medical Affairs (IMA) head and act as their primary advisor and point person. This strategic and operational position is responsible for developing and ensuring the execution of strategic plans, projects, and commitments which drive operational efficiencies and connectivity across stakeholder groups. Additionally, this role is responsible for keeping the IMA Head apprised of key initiatives, providing project oversight and management of cross-functional and key initiatives, and ensuring appropriate coordination and management of budgets and integrated project plans for the IMA. The Strategic Assistant is a key partner on a variety of strategic, operational, and organizational matters. This role provides dedicated support to the IMA head in achieving team objectives, shaping the agenda, and ensuring execution through operational management and moderation of governance bodies, leadership team, and projects. It supports proactively identifying and resolving upcoming issues and improving processes. About the Role Key Responsibilities: Serves as a strategic thought partner with the IMA Head, providing high-level executive support associated with complex problems, current and future initiatives, strategies, and budgets. Assists the IMA Head in day-to-day responsibilities, ensuring coordination of cross-organizational activities. Develops a clear understanding of IMA ambition and key priorities to provide operational leadership as a member of the International leadership team. Demonstrates collaborative leadership and influence necessary to ensure alignment among key stakeholders and seamless execution of deliverables. Works cross-functionally to ensure the strategic and operational plans are delivered Works with Finance partners and IMA leaders to ensure budget alignment and validation with the head of IMA Serves as an ambassador for the IMA Head and leadership team, facilitating communication with other members of the organization as needed. Leads IMA LT meetings including agenda, action planning, tracking deliverables, and KPIs. Responsible for IMA team’s governance: Drives agenda, moderates meetings, and minutes. Actively shapes team priorities and the alignment of goal setting across cross-functional teams. Ensures effective operational management of critical decision-making bodies. Looks for opportunities to simplify and drive synergies between teams in the organization. Coordinates and anticipates timely preparation of IMA content for critical internal and external meetings. Supports change management, culture, and OD initiatives together with other IMA LT members. Builds and supports the execution of an internal communications plan aligned to IMA priorities and cultural agenda. Essential requirements: Minimum BS/BA degree, preferably MA, MBA Strategic Consulting background. Strategic capability and commercial acumen. Over 5 years in the Pharma industry, ideally including in a regional/global environment or in a major consultancy. 5+ years of experience in project management, operations, and/or people leadership. Ability to influence without authority. Ability to work independently and collaboratively, strong leadership and organizational skills, and able to drive multiple projects to successful, timely completion. Ability to communicate ideas and data both verbally and written in a persuasive and appropriate manner. Analytical skills to identify the root cause of problems/opportunities and determine possible solutions. Highly autonomous, self-directed, and collaborative. Energetic and hands-on self-starter with a desire to learn new things quickly. Proven ability to refine and improve the organization’s capabilities. Demonstrated track record of effectively handling key organizational matters. Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis has embraced a bold strategy to drive a company-wide digital transformation. Our objective is to position Novartis as an industry leader by proactively adopting digital technologies that foster innovative approaches to hasten drug discovery and development. By utilizing both internal and external Research & Development data with the power of data science, predictive models, generative AI, and machine learning, our objective is to identify new targets, create more effective therapeutic molecules, better predict drug pharmacokinetics and safety risks, refine clinical trial design, and significantly shorten development cycles. The Artificial Intelligence & Computational Sciences (AICS) team leads Biomedical Research (BR) in exploring and applying advanced AI and ML methodologies to generate novel drug discovery insights, and to speed and improve drug discovery efficiency whilst focusing on patients’ needs. AICS partners with drug discovery teams, raises the level of AI expertise across BR and ensures that BR science keeps up with the rapidly evolving ecosystem of AI technologies by connecting with AI leaders in academia and industry. This rolewithintheAI Methodsgroup of AICS will be tasked with critical assessment of the model landscape, identifying opportunities for methodological innovation, and building the right AI approaches, algorithms, models and workflows to maximize impact on key domains areas of biomedical research that will potentially lead to developing better drugs, faster. About the Role Responsibilities: Work with a team of AI researchers, data scientists and SMEs with core domain expertise to develop and deliver focused, robust, performant AI algorithms and solutions to accelerate drug discovery. Stay informed about the latest AI methods, increase understanding of the problem domain, and ask detailed questions to identify potential areas for innovation in AI across the drug discovery pipeline. Promote awareness of advancements in AI methods for addressing key research questions within biomedical research. Fluently adopt Engineering and Product Development resources to ensure the adoption of AI solutions . Help position AI-aided drug discovery contributions to deliver and support progress of BR’s portfolio, enable new kinds of therapeutic discoveries, shorten cycle times, and increase efficiency. Collaboration & partnership A respectful, team-player attitude is an absolute must. Regularly communicate, engage, align with AICS teams, broader data science community, and senior scientists. Initiate and lead key high-value internal collaborations across BR. Help design translatable metrics for AI models that will lead to tangible impact in collaboration with BR DAs and FAs. Collaborate cross-functionally to translate model outputs into actionable hypotheses and guide experimental design. What you’ll bring to the role: 4+ years of significant experience in innovation, development, deployment and continuous support of Machine Learning and modeling. Strong hands-on coding proficiency in Python and deep learning frameworks and an expertise in bringing advanced analytics insights and actions to a large r esearch organization Wide exposure to representation learning, deep generative modeling, probabilistic reasoning, and explainability approaches. with a deep passion for understanding and explaining the technical concepts underlying ML approaches. Strong understanding and experience in using version control systems for developing software (e.g. GitHub, git, subversion, bitbucket, etc.) with expertise in large-scale model training, distributed computation, and foundation model adaptation. Publications, patents, or open-source contributions that demonstrate machine learning innovation and expertise, with passion for understanding emerging technologies and how they can integrate into business solutions Ability to balance requirements, manage expectations, and drive effective results using a proactive can-do attitude towards identifying and resolving issues, as well as a proven ability to work exceptionally well within complex matrixed teams. A deep curiosity and passion for biomedical sciences driven therapeutic discovery. Nice to have: Experience with applying ML to one or more functional areas of core drug discovery like target identification, computational chemistry, protein structure modelling and design or translational medicine is a plus. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Relevant areas of desired expertise: Transformer architectures (Text, Vision, DNA/amino-acid sequences, Gene expression vectors);Long-context transformersandefficient attention mechanisms; diffusion models;flow matching;energy-based models; multimodal architectures; graph neural networks; geometric deep learning; Bayesian optimization; Reinforcement learning; Active learning; Variational Inference; Self-supervised learning; Contrastive learning; Domain adaption; Test-time adaptation Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Der CBC Equipment Specialist ist verantwortlich für den GMP-konformen Herstellungsprozess von Zellbanken im Basel Cell Bank Center. Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role Major Accountabilities Teilnahme an den Herstellungsprozessen Durchführung aller notwendigen Verarbeitungsschritte des Zellbankwesens mit höchstemKenntnisstand der aseptischen/niedrigen Keimbelastungstechnik (Auftauen, Zellpassage,Zellzählung und Einfrieren der Zellbank) Ausführung sämtlich zugewiesener Tätigkeiten gemäß dem Produktionsplan und der gültigenGMP-, Arbeits-,Betriebs-, Umwelt- und Sicherheitsanweisungen und -richtlinien Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagenund -räume Verantwortung für die Haushaltsführung des Produktionsbereichs (Reinigung, Ordnung, 5S, usw.) Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien(HSE) Anwendung und Durchsetzen der aktuellen GMP-Regeln Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften Education: Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen, Technischer Abschluss; Universitatsabschluss (Chemieingenieurwesen, pharmazeutische Technologie, Biotechnologie, Biochemie) fur einige Technologieplattformen erwOnscht oder gleichwertige Erfahrung Languages: Grundkenntnisse in Englisch und Beherrschung der Landessprache des Standorts - German Experiences: Mindestens 2 Jahre abgeschlossene Berufserfahrung als Novartis-Gerätebediener oder (vorzugsweise) 5 Jahre in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are committed to fostering a source of versatile, commercially focused, and inspiring talent. As part of our ongoing quest to embody proactive thought leadership, we emphasize on sharing our enterprise strategies while remaining focused on addressing the unique country’s needs as a value-added solution focused partner. Join the International HEOR & PCO Team, a pivotal partner in International Value & Access, leading with excellence the evidence generation to demonstrate the value of our innovative medicine portfolio. An opportunity has arisen for an experienced Senior HTA Statistician to apply innovative statistical approaches to complex challenges in health technology assessment (HTA). This role offers the chance to lead the evidence synthesis of patient data from clinical, observational, and real-world data studies supporting HTA submissions, in a flexible and collaborative environment. The role is responsible for leading the design and execution of evidence-synthesis for HTA submissions incl. EU HTA JCA Dossier and for health economic models. Position applies methodological and analytical expertise to predict the value of Novartis assets and develop strategies on how best to demonstrate this to external decision makers. Role will strategically and effectively communicate, and tailor generated evidence to multiple stakeholder audiences. About the Role Key responsibilities: As part of the HEOR & PCO Team: Develop core global Indirect Treatment Comparison (ITC) plan for HTA, payer and other Access stakeholder assessments, submissions, and negotiations. Lead publications associated with these to meet business objectives. Provide strategic, methodological, and analytical support to regions and top countries with adaptation of the Indirect Treatment Comparison (ITC) for local HTA submissions and support the local assessment of HTA strategy. Coordinate data requirements across evidence generations functions (Clinical Development; Medical Affairs/Biostat and HEOR & PCO) to support Pricing & Reimbursement. Set-up systems internally to proactively capture key HTA analytic requirements across key international markets to inform and optimize key internal deliverables e.g., statistical analysis plans. Track key HTA statistics priorities and sequence them aligning with resource availability and risks. Identify need for preliminary ITCs to inform value proposition, development, pricing and commercial strategic forecast and decisions. Lead and facilitate the sharing of best practices and key learnings across regions, countries and cross-functional partners. Stay on top of innovative techniques, using robust analytical techniques leveraging available clinical data and published information to inform pricing and market access strategy. Collaborate with the MA Biostats team for trial analyses, HTA challenges, and statistical analyses. Act as a Strategic Partner for key partners from HEOR & PCO and International Value & Access (Therapeutic Area Access, Pricing) to ensure alignment to brand and commercial, access and evidence strategy. Ensure optimal utilization of comparative evidence through partnership with teams generating payer & promotional materials, generating regulatory dossiers and publications. Provide mentoring and coaching support to junior members of evidence modelling teams and across function. Essential requirements: The ideal candidate will possess a strong background in statistics, with relevant experience in HTA and clinical research. MSc/PhD in Statistics, Biostatistics, or a related field. Experience from pharmaceutical industry or life-science consultancy 6-8 years relevant experience in consultancy or pharmaceutical industry in Evidence Synthesis, Health Economics, Health Technology Assessment, or related area Strong understanding of clinical drug development and HTA-related regulations and processes Local HTA experience including experience with country HTA submissions Strong understanding of statistical methodologies for indirect treatment comparisons (ITCs) and population-adjusted indirect comparison (PAIC) Proficiency in statistical software such as R and/or SAS Strong interpersonal and scientific communication skills. Excellent problem-solving abilities and attention to detail Ability to lead in a matrix environment and work collaboratively in interdisciplinary cross-functional teams Location: This role can be based in the UK, London but also based in Basel, Switzerland and Dublin, Ireland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10064204 Oct 23, 2025 Switzerland Summary Join a dynamic team where you will be managing high-impact patent litigation cases. You'll work closely with both in-house and external counsel, driving strategic litigation efforts and overseeing key operational processes. This role offers the opportunity to lead projects that enhance litigation workflows, contribute to budget planning, and deliver insightful IP reporting-making a real difference in how we protect and leverage our intellectual property. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities : Provides and utilizes IP expertise to support several IP Counsels and the IP function as a whole - championing quality, collaboration and operational excellence in the Department. Contributes to the implementation and application of IP policies and guidelines - providing non-legal advice to business colleagues, collaborating with the business under the supervision of project leads to ensure business goals are met in an efficient and timely manner. Contributes to the #OneNovartisIP culture - Proactively and autonomously supports in-house patent litigation counsel and attorneys in preparation for patent enforcement and defense, by interacting with local counsel and local Business Franchises. Maintain and share advanced knowledge of latest litigation rules and adapting practices to comply. Monitor and updating Anaqua on a daily basis. Communicate effectively with colleagues, agents and other associates - Actively participate in litigation group and cross-divisional meetings as needed - being flexible to provide support in other areas within the Patent Support team (i.e. invoicing and data input). Leads teams in development of procedures and processes - ability to conduct meetings as needed; Recommends areas/systems of possible improvement in efficiencies in procedures. Leads projects relating to litigation processes/operations, driving the successful implementation of new and revised processes and guidelines. Autonomously supports in-house patent litigation counsel and attorneys on matters such as patent ownership and licensing structure. Manages the flow of information by acting as a contact point for local lawyers/local team for patent litigation matters - using Litigation database document and information management; familiarity with patent databases e.g. PatBase, Espacenet, etc. Attend and draft memorandum of litigation meetings with local counsel and local business, provide action points and follow up on agreed objectives. Manages the IP Litigation budget process; drive the preparation of and deliver the various litigation budget forecasts by liaising with internal and external attorneys & counsel, as well as BPA, assisting in the review, as appropriate. Responsible for full project life cycle including Liaises with department eBilling coordinator, utilizes Anaqua to record and report litigation matters, litigation reporting and leads the interactions on behalf of IP Litigation Project Team with any third-party co-owners, licensors, patentees. Supervision of junior litigation paralegals, local litigation team coordinators and new team members providing guidance on internal and external processes, litigation database management, etc. Essential Requirements: Relevant degree, or equivalent experience. Paralegal qualification/ certifications or equivalent Proficiency in English required - spoken & written, other languages is an asset. Demonstrated professional experience as an IP paralegal or equivalent in an IP litigation law firm or corporation. Extensive experience in autonomously providing complex patent litigation support in a large multinational company preferably in-house, or in a law firm. Able to work autonomously in preparation of draft schedules and supporting documents for subsequent attorney review - able to communicate with business clients in multiple countries. Excellent team-player with exemplary interpersonal skills - Reliable, service-oriented with impeccable integrity and willingness to learn. Proven ability to balance and identify priorities in daily work, manage varying workload levels, ensuring a consistent work product, and support the IP team efficiently and in a solution-oriented, contextualized manner. Proactive approach to project/workstream involvement. Able to consider the needs of the team and where they can contribute, implementing or suggesting solutions prior to being instructed. Active participation in relevant projects - willingness to learn and develop in role. Extensive experience in autonomously managing complex patent litigation support in a large multinational company, preferably in-house, or in a law firm. IP Identified leadership potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Join a dynamic team where you will be managing high-impact patent litigation cases. You'll work closely with both in-house and external counsel, driving strategic litigation efforts and overseeing key operational processes. This role offers the opportunity to lead projects that enhance litigation workflows, contribute to budget planning, and deliver insightful IP reporting—making a real difference in how we protect and leverage our intellectual property. #Hybrid Location: Basel, Switzerland About the Role Key Responsibilities : Provides and utilizes IP expertise to support several IP Counsels and the IP function as a whole - championing quality, collaboration and operational excellence in the Department. Contributes to the implementation and application of IP policies and guidelines - providing non-legal advice to business colleagues, collaborating with the business under the supervision of project leads to ensure business goals are met in an efficient and timely manner. Contributes to the #OneNovartisIP culture - Proactively and autonomously supports in-house patent litigation counsel and attorneys in preparation for patent enforcement and defense, by interacting with local counsel and local Business Franchises. Maintain and share advanced knowledge of latest litigation rules and adapting practices to comply. Monitor and updating Anaqua on a daily basis. Communicate effectively with colleagues, agents and other associates - Actively participate in litigation group and cross-divisional meetings as needed – being flexible to provide support in other areas within the Patent Support team (i.e. invoicing and data input). Leads teams in development of procedures and processes - ability to conduct meetings as needed; Recommends areas/systems of possible improvement in efficiencies in procedures. Leads projects relating to litigation processes/operations, driving the successful implementation of new and revised processes and guidelines. Autonomously supports in-house patent litigation counsel and attorneys on matters such as patent ownership and licensing structure. Manages the flow of information by acting as a contact point for local lawyers/local team for patent litigation matters – using Litigation database document and information management; familiarity with patent databases e.g. PatBase, Espacenet, etc. Attend and draft memorandum of litigation meetings with local counsel and local business, provide action points and follow up on agreed objectives. Manages the IP Litigation budget process; drive the preparation of and deliver the various litigation budget forecasts by liaising with internal and external attorneys & counsel, as well as BPA, assisting in the review, as appropriate. Responsible for full project life cycle including Liaises with department eBilling coordinator, utilizes Anaqua to record and report litigation matters, litigation reporting and leads the interactions on behalf of IP Litigation Project Team with any third-party co-owners, licensors, patentees. Supervision of junior litigation paralegals, local litigation team coordinators and new team members providing guidance on internal and external processes, litigation database management, etc. Essential Requirements: Relevant degree, or equivalent experience. Paralegal qualification/ certifications or equivalent Proficiency in English required – spoken & written, other languages is an asset. Demonstrated professional experience as an IP paralegal or equivalent in an IP litigation law firm or corporation. Extensive experience in autonomously providing complex patent litigation support in a large multinational company preferably in-house, or in a law firm. Able to work autonomously in preparation of draft schedules and supporting documents for subsequent attorney review - able to communicate with business clients in multiple countries. Excellent team-player with exemplary interpersonal skills - Reliable, service-oriented with impeccable integrity and willingness to learn. Proven ability to balance and identify priorities in daily work, manage varying workload levels, ensuring a consistent work product, and support the IP team efficiently and in a solution-oriented, contextualized manner. Proactive approach to project/workstream involvement. Able to consider the needs of the team and where they can contribute, implementing or suggesting solutions prior to being instructed. Active participation in relevant projects - willingness to learn and develop in role. Extensive experience in autonomously managing complex patent litigation support in a large multinational company, preferably in-house, or in a law firm. IP Identified leadership potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible. Step into a role where your organizational excellence and proactive mindset will directly support strategic leadership across international teams. As Executive Assistant to the International NS Head, you’ll be at the heart of global initiatives, ensuring seamless operations and enabling high-impact decision-making. This is more than an administrative position—it’s a chance to shape how Novartis delivers innovation and collaboration across borders. About the Role Key Responsibilities Provide executive-level administrative support to the International NS Head and team Coordinate complex scheduling across global time zones for meetings and trainings Organize logistics for international business travel and submit expense reports Manage on-site, off-site, and virtual meetings with precision and discretion Lead administrative projects with defined scope, timelines, and deliverables Streamline and optimize administrative processes for improved team efficiency Act as liaison for departmental guidelines and services across internal teams Maintain confidentiality while handling sensitive information and communications Support cross-functional collaboration and contribute to special initiatives Model Novartis values through proactive ownership and operational excellence Essential Requirements Proven ability to manage multiple priorities with efficiency and professionalism Strong organizational skills and attention to detail in a fast-paced environment Excellent verbal and written communication skills across diverse audiences Demonstrated discretion in handling confidential and sensitive information Bachelor’s degree or equivalent professional experience Advanced proficiency in MS Word, Excel, and PowerPoint Ability to work independently with minimal supervision High tolerance for deadlines and conflicting priorities Desirable Requirements Experience supporting senior leadership in a global, matrixed organization Proven ability to manage cross-cultural interactions and foster inclusive collaboration Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10064284 Dec 09, 2025 Switzerland Summary #LI-Hybrid Location: Basel, Switzerland Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible. Step into a role where your organizational excellence and proactive mindset will directly support strategic leadership across international teams. As Executive Assistant to the International NS Head, you-ll be at the heart of global initiatives, ensuring seamless operations and enabling high-impact decision-making. This is more than an administrative position-it-s a chance to shape how Novartis delivers innovation and collaboration across borders. About the Role Key Responsibilities Provide executive-level administrative support to the International NS Head and team Coordinate complex scheduling across global time zones for meetings and trainings Organize logistics for international business travel and submit expense reports Manage on-site, off-site, and virtual meetings with precision and discretion Lead administrative projects with defined scope, timelines, and deliverables Streamline and optimize administrative processes for improved team efficiency Act as liaison for departmental guidelines and services across internal teams Maintain confidentiality while handling sensitive information and communications Support cross-functional collaboration and contribute to special initiatives Model Novartis values through proactive ownership and operational excellence Essential Requirements Proven ability to manage multiple priorities with efficiency and professionalism Strong organizational skills and attention to detail in a fast-paced environment Excellent verbal and written communication skills across diverse audiences Demonstrated discretion in handling confidential and sensitive information Bachelor-s degree or equivalent professional experience Advanced proficiency in MS Word, Excel, and PowerPoint Ability to work independently with minimal supervision High tolerance for deadlines and conflicting priorities Desirable Requirements Experience supporting senior leadership in a global, matrixed organization Proven ability to manage cross-cultural interactions and foster inclusive collaboration Benefits: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division International Business Unit Marketing Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Facilities & Administration Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Facilities & Administration International Switzerland Job ID REQ-10064284 Executive Assistant to International NS Head Apply to Job (link is external)

Summary #LI-Hybrid Join us as the Site Quality Head and lead the charge in ensuring world-class quality and compliance at one of Novartis’ strategic manufacturing sites. In this pivotal role, you’ll shape quality standards, safeguard patient trust, and drive operational excellence across all GxP functions. Your leadership will not only uphold regulatory compliance but also inspire a culture of continuous improvement and collaboration. If you’re passionate about making a tangible impact on global healthcare, this is your opportunity to lead with purpose. About the Role Key Responsibilities: Lead the Site Quality organization and foster a culture of compliance and continuous improvement. Ensure full adherence to cGMP, regulatory requirements, and Novartis Quality Manual standards. Act as Qualified Person (Technical Responsible Person) for site operations. Oversee quality governance across all GxP functions and ensure robust risk management. Final responsible to approve or reject raw materials, facilities, utilities, and finished products. Drive execution of training programs and maintain compliance with DI and eCompliance standards. Manage internal and external audits, inspections, and regulatory submissions. Ensure effective complaint investigations and exception management processes. Essential Requirements: 10–15 years of experience in the pharmaceutical or chemical industry. University degree in Chemistry or Pharmacy or related discipline (per Swiss law also Biology would be acceptalbe) Strong knowledge of regulatory requirements and cGMP standards. Experience with FDA/Swissmedic regulations and compliance. Dynamic, resilient, and versatile approach to problem-solving. Demonstrated people leadership and team management skills. Excellent communication skills and ability to collaborate across functions. Fluency in German and English. Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you passionate about pharmaceutical innovation and eager to see how cutting-edge technologies shape the medicines of tomorrow? Join our Pharmaceutical Development team for a 6–12 month internship and dive into the world of advanced drug formulation. Based in a dynamic industrial setting, you’ll work hands-on in our labs and technicum to explore Solid Oral Dosage forms and novel processing technologies that accelerate medicine delivery to patients worldwide. During your internship, you’ll gain practical experience in developing and characterizing dosage forms and their components, while learning how these translate into scalable production processes. You’ll collaborate with experts in pharmaceutical science, technology, and data-driven innovation—building skills that matter for the future of healthcare. About the Role Location: Basel, Switzerland, #LI-Onsite This internship is limited to 6 - 12 months, with a start date as soon as possible. Please note that we can only accept applicants who are eligible to work in Switzerland. Key Responsibilities: Support the formulation and process development for oral drug products and perform feasibility trials to advance the assessment and innovation of new technologies, under supervision of an experienced team member Perform related work in our galenical lab (non-GMP) incl. characterization of material properties Utilize data digital tools (e.g. e-Lab Journal, digital IPC data handling, digital data recording, data visualization tools) Provide raw data documentation, evaluation and interpretation of results incl. presentations at internal meetings. Propose and provide input for the design of next experiments Adherence to quality, quantity, and timelines for all assigned tasks. Adherence to Novartis standards, in particular, quality, ethical, health, safety, and environment (HSE), and information security (ISEC) standards. Essential Requirements : You have a recent degree in Pharmaceutical Sciences, Pharmaceutical Engineering, Chemical Engineering or a related discipline (e.g. MSc, or BSc or a College of Applied Science Diploma or equivalent). Good scientific or technical knowledge in galenics / pharmaceutical technology / formulation- and/or process development Special interest in formulation, pharmaceutical technology/processing and/or physicochemical properties / pharmaceutical material including curiosity and interest in performing lab work Excellent Communication and organizational skills with respect to planning and tracking of commitments Languages: Proficiency in English (oral and written) required, German skills are advantageous Desirable Requirements : Experience in working with active ingredients in a lab setting incl. experience with related HSE principles Experience or general digital severity in actively applying data-digital tools like e-LabNotebook, digital documentation and data recording tools Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, color, race, sexual orientation, nationality or disability. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Application deadline: December 24 EOB. Please submit a cover letter that includes your motivation for the position and from when you will be available and for how long. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Linienführer:in Primärverpackung – Feste Darreichungsformen Für unser Team in der Primärverpackung fester Darreichungsformen suchen wir per sofort eine:n motivierte:n und erfahrene:n Linienführer:in mit fundierten GMP-Kenntnissen, ausgeprägtem technischem Verständnis und Teamgeist. In dieser Funktion sind Sie verantwortlich für die termingerechte Ausführung der Ihnen zugewiesenen Herstellungs- und Verpackungsaufgaben gemäß Produktionsplan unter Einhaltung aller GMP-, Sicherheits- und Umweltrichtlinien. About the Role Hauptaufgaben Maschinelles Verpacken von Arzneimitteln (Flaschen und Blister) an modernen, komplexen Verpackungsanlage Führen, Einteilen und Unterstützen des Anlagenteams der zugewiesenen Produktionslinie Umrüsten/ Einrichten und Anfahre/Betreiben der Produktionsanlagen Verantwortung für die Anlagenreinigung und Desinfektion Durchführung von In-Process-Control (IPC)-Kontrollen Auftragsvorbereitung in Zusammenarbeit mit Planung, Lager und Prozessexpert:innen Beheben kleiner technischer Störungen; Unterstützung bei Qualifizierungs- und Instandhaltungsarbeiten nach Bedarf Einarbeitung neuer Mitarbeitender im Bereich Korrekte, vollständige und nachvollziehbare Dokumentation der Tätigkeiten auf Papier und in der elektronischen Chargendokumentation (z. B. SAP) gemäß GMP Fachansprechpartner:in für die zugewiesenen Anlagen und Prozesse bei Audits und Inspektionen Sicherstellung und Durchsetzung von GMP- und HSE-Vorgaben Mitwirkung am Housekeeping (Ordnung, Sauberkeit, 5S) im Produktionsbereich Kontinuierliche Verbesserung: Identifikation von Schwachstellen und Vorschlag von Maßnahmen (Organisation, Prozess, Sicherheit, Hygiene) Teilnahme an allen funktionsrelevanten Schulungen und Sicherstellung des geforderten Trainingsstandes Bereitschaft zu Mehrarbeit bzw. Schichtarbeit (Früh- und Spätschicht), sofern erforderlich Zusammenarbeit mit anderen Einheiten und Einsatz in angrenzenden Bereichen bei Bedarf (z. B. weitere Primärverpackungslinien, Lager, Sekundärverpackung, Manuelle Handverpackung) Erforderliche Fähigkeiten Abgeschlossene Ausbildung im Bereich Chemie / Pharma oder Technik Berufserfahrung als Linienführer:in/Linienleiter:in im GMP-regulierten Umfeld, idealerweise in der Verpackung pharmazeutischer Produkte (Flaschen und Blister)Ausgeprägte technische Kompetenz mit Erfahrung im Einrichten, Bedienen und Störungsbeheben an automatisierten Produktionsanlagen Hohes Pflicht- und Qualitätsbewusstsein; sorgfältige Dokumentations- und Arbeitsweise sowie Ordnung und Sauberkeit am Arbeitsplatz Konstruktiv, lösungsorientiert, verantwortungsbewusst; tiefes Verständnis für Qualität und Compliance Hohe Selbstmotivation und schnelle Auffassungsgabe zur Einarbeitung in neue Tätigkeiten Erfahrung in der Führung kleiner Teams und in der Mitarbeitendenausbildung von Vorteil Gute IT- sowie MS-Office-Kenntnisse (z. B. Erstellung einfacher Arbeits- oder Bedienungsanweisungen) Fundierte Kenntnisse im GMP-Umfeld und in hygienekritischen Bereichen Organisationstalent und Durchsetzungsvermögen Sehr gute Deutschkenntnisse in Wort und Schrift; Englischkenntnisse von Vorteil Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland #onsite We have a fantastic opportunity for a Oligonucleotide Chemist in our CHAD department here in Basel. About the Role Your responsibilities: Your responsibilities include, but are not limited to: Defining fit-for-purpose synthesis strategy for drug substance manufacturing and Health Authority documentation. Develop efficient and scalable oligonucleotide processes on relevant projects within Novartis portfolio across different scales. Be part of the Oligo chemist / engineering team to develop and optimize syntheses used in process R&D. Investigate various approaches for oligonucleotide preparation and evaluate their potential by applying cutting-edge automated platforms. Ensuring utilization of state-of-the-art technologies and science. Efficient use of lab resources. Maintaining oversight on process safety. Co-leading the process transfer to pilot plants. Serving as consultants for troubleshooting during campaigns. Collaborating with internal and external stakeholders or partners Collaborate with diverse experts in the areas of Nucleic Acid Chemisty, Process Chemistry, Process Engineering and Analytics. What you’ll bring to the role: A completed PhD in Organic Chemistry, or Chemical engineering PostDoc with a focus on oligonucleotides processes. Experience in developing platform synthesis concepts for oligonucleotides Experience in process development using state of art oligo synthesizers. Experience in downstream processing including TFF and chromatographic processes An excellent track record of original research and extensive experience in using “state of the art” technologies. Fluency in English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary ~ Bieten Sie Qualitätssicherung und Compliance-Aufsicht für Entwicklungs- und Forschungsfunktionen. Fördern Sie die Überwachung von Qualitätsmanagementsystemen und -initiativen innerhalb der globalen, regionalen und Länderorganisation und stellen Sie die Einhaltung der geltenden regulatorischen Anforderungen der Gesundheitsbehörden (z. B. GCP, GLP, GMP, PV, IP) und der Novartis-Verfahren und Qualitätsstandards sicher. Vorbild für gutes Qualitätsverhalten bei gleichzeitiger Förderung einer Qualitätskultur (z. B. richtiges erstes Mal usw.), um die nicht-qualitativ hochwertigen Stakeholder (z. B. NIBR, GDD) positiv zu beeinflussen. Entwickeln, vorantreiben und/oder unterstützen Sie Qualitätsplaninitiativen, um Die Organisationsstrategie, Mission und Vision zu erreichen. About the Role Key Responsibilities: Proactively provide QA leadership to the business strategy for assigned programs/trials by ensuring considerable organization awareness (e.g. Interrelationship of departments and business priorities), Drive implementation of quality strategy within Global Clinical Team (GCT )/ Clinical Trial Team (CTT) under responsibility Regularly monitor the implementation of the annual Quality Plan pertaining to the assigned programs/studies Ensure adequate oversight of proactive quality risk management process in the overseen areas including quality risk assessments and submission/inspection readiness activities and ensure that Clinical Trial Process (CTP) are in control Provide robust and clear quality oversight in the following areas of clinical development: Support/collaborate with key stakeholders (e.g., Country Development Quality (CDQ), Development Units (DUs), GCT and/or CTT members) to ensure that risks are detected and remediated. Support core governance for quality incident management for critical and major deviations pertinent to the programs being assigned and ensure timely escalation when required. Provide Good Clinical Practice (GCP) guidance to day-to-day questions arising from Clinical trials deliverables. Collaborate with Country Development QA and External Service Providers (ESP) QA to drive initiatives relevant to internal monitoring and outsourced activities Quality oversight. Support inspections preparation and facilitation in collaboration with other QA groups within Research & Development Quality (RDQ). Support audits and inspections follow-up activities including Corrective & preventative Actions (CAPA) preparation. Actively leverage audit/inspection outcomes/trends to sustain improvement in clinical trials conduct. Active participation in continuous improvement initiatives (including Work streams) and ensure that areas identified as weaknesses are properly being addressed and executed for sustainability Be QA point of contact for the defined trials and attend the meetings and ensure quality is embedded in the decision taking processes. Essential Requirements: Bachelor’s degree in life science or healthcare field required. Advanced degree or equivalent education/degree in life sciences/healthcare preferred (PhD/MD/ PharmD/ Masters). 7 years of involvement in regulated activities (GCP/ Pharmacovigilance (PV)), clinical development and/or QA positions. Broad understanding of global expectations of Health Authorities in the area of Clinical Development and profound understanding of the science of product development. Ability to work independently and in a global/matrix environment. 3 or more years’ experience in managing projects. Strong skills in GCP, quality and/or clinical development Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10067104 Nov 20, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. About the Role About the role: The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. Key responsibilities: Lead a research team and collaborate with groups across BR Oncology Contribute to biomarker strategies and supervise translational experimental plans for various RLT drug discovery programs Design and conduct translational studies, dissect the biological mechanisms driving response and resistance to RLT, and develop rational drug combinations. Mentor and develop associates with various levels of experience Essential Requirements: Ph.D. in molecular, cellular, cancer biology or related fields. Minimum 2 years of Postdoctoral and/or industry experience in an Oncology/Cancer biology relevant field Recognised academic publication record Deep understanding of cancer cell biology, familiarity with innovative cell and molecular biology techniques. Excellent creative thinking and problem-solving skills, scientific curiosity. Proficiency in working collaboratively and flexibly on various projects Strong communication skills, at ease with conveying complex scientific concepts Desirable Requirements: Strong foundational knowledge and experience working on cell death mechanisms, experience in the field of DNA damage response and repair, radiobiology or RLT. Expertise in prostate cancer biology Proficiency with data mining and computational skills. Track record in managing a research team and scientific projects Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Location: Basel, Switzerland #onsite Role Purpose: The Technical Project Leader (TPL) formulates and drives a scientifically sound and business driven technical project strategy for Technical Research & Development (TRD), including financial planning, risk assessments and contingency planning as appropriate and in line with the overall Research & Development Project Team strategy and TRD objectives. The TPL will lead the TRD-development of Mixed Modality, Small Molecule and/or Biologics projects as well as leading, representing, managing, and supporting the CMC team, ensuring alignment with other departments and functions inside and outside of TRD as well as third parties as appropriate About the Role Strategy Establishes technical development plans in line with priority classification of project, gated by clinical readouts as appropriate and with an enterprise view in consideration of overall portfolio priorities. Establishes high level summaries for presentation to management and stakeholders. Has advanced skill to identify, assess, manage, and communicate CMC risks / program risks. Due to seniority and experience, can handle more difficult risks, issues in more complex projects and handle multiple risks of DS/DP/Device even with junior CMC team members. Provides drug development expertise in addition to technical expertise. Follows standard process but at the same time thinks outside the box based on existing knowledge. Challenges the status quo, is curious and fosters creativity of team members and own creativity. Leverages existing knowledge and implements in the overall Global Project Team project strategy. Continues to follow and stands behind Global Project Team decisions. For complex late phase programs, supports Senior TPL for defined work packages. Interfaces Participates in boards and joins and/or can lead discussions in leadership teams. Is highly skilled in collaborative settings (i.e., external vs internal, CROs, DDs, in-/out-licensing settings). Approaches/analyses issues and collaborates with other line functions for optimal solutions. Takes into account multiple stakeholder perspectives and approaches to find optimal solutions and build commitment and consensus. Provides knowledge of industry, main competitors, customers and external environment – this includes healthcare industry and global industry, digital and technological advancements. Shares knowledge with CMC community, e.g., by lessons learned sessions. Uses knowledge and experience to challenge and influence CMC line functions and/or Global Project Team in background of the overall drug development strategy / industry insight. Actively contributes to Global Project Team beyond CMC line functions. Is able to navigate and manage the complexity of the disease area GPTs. Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. People Learns to manage teams/stakeholders appropriately (utilizing their support). Brings forward sound proposals and shares lessons learned, without passing the blame. Anticipates setbacks and stays in control – takes criticism as intended for situations (not personally or toward particular individuals). Recovers quickly from problems and setbacks. Exhibits servant leadership and provides mentoring/coaching to junior TPLs, line functions and CMC team members to support their professional and personal growth. Leads by example and drives decisions. Generic Activities Leads CMC teams (in a matrix set up). Leads CMC team and other meetings (agendas, minutes, action tracker, moderation). Acts as link and conveys CMC topics between Global Project Team, CMC line functions and CMC boards to support decision making. Sets the CMC team and sub-teams objectives in line with the GPT / PoC Team objectives. Communicates transparently. Is able to communicate and adjust the message based on the audience (i.e., level of technical detail, etc.). Has financial and resource oversight, budget accountability/oversight. Takes responsibility for successes and failures of own and team's work, holds self and team accountable for outcomes (shifts priorities to ensure success). Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. Ideal Background Education (minimum/desirable): Advanced degree in life science, engineering or equivalent. Languages: Fluent in English Experience/Professional requirement: Successfully demonstrated several years (minimum of 2-3 years) of directly related experience as functional project leader and relevant experience as Associate TPL or equivalent. Has strong scientific/technical knowledge & understands technical development tasks for Small Molecules or Biologics (minimum) and Mixed Modalities (ideal). Is able to establish/maintain DS/DP/Device supply plan (in alignment with the clinical supply project lead). Has fundamental knowledge of GMP and regulatory requirements. Has a solid cross-functional knowledge (PK/PD, tox, clinical, commercial) regarding drug development. Manages end to end technical drug development and knowledge. Completed basic project management training. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10067576 Dec 03, 2025 Switzerland Summary Location: Basel, Switzerland #onsite Role Purpose: The Technical Project Leader (TPL) formulates and drives a scientifically sound and business driven technical project strategy for Technical Research & Development (TRD), including financial planning, risk assessments and contingency planning as appropriate and in line with the overall Research & Development Project Team strategy and TRD objectives. The TPL will lead the TRD-development of Mixed Modality, Small Molecule and/or Biologics projects as well as leading, representing, managing, and supporting the CMC team, ensuring alignment with other departments and functions inside and outside of TRD as well as third parties as appropriate About the Role Strategy Establishes technical development plans in line with priority classification of project, gated by clinical readouts as appropriate and with an enterprise view in consideration of overall portfolio priorities. Establishes high level summaries for presentation to management and stakeholders. Has advanced skill to identify, assess, manage, and communicate CMC risks / program risks. Due to seniority and experience, can handle more difficult risks, issues in more complex projects and handle multiple risks of DS/DP/Device even with junior CMC team members. Provides drug development expertise in addition to technical expertise. Follows standard process but at the same time thinks outside the box based on existing knowledge. Challenges the status quo, is curious and fosters creativity of team members and own creativity. Leverages existing knowledge and implements in the overall Global Project Team project strategy. Continues to follow and stands behind Global Project Team decisions. For complex late phase programs, supports Senior TPL for defined work packages. Interfaces Participates in boards and joins and/or can lead discussions in leadership teams. Is highly skilled in collaborative settings (i.e., external vs internal, CROs, DDs, in-/out-licensing settings). Approaches/analyses issues and collaborates with other line functions for optimal solutions. Takes into account multiple stakeholder perspectives and approaches to find optimal solutions and build commitment and consensus. Provides knowledge of industry, main competitors, customers and external environment - this includes healthcare industry and global industry, digital and technological advancements. Shares knowledge with CMC community, e.g., by lessons learned sessions. Uses knowledge and experience to challenge and influence CMC line functions and/or Global Project Team in background of the overall drug development strategy / industry insight. Actively contributes to Global Project Team beyond CMC line functions. Is able to navigate and manage the complexity of the disease area GPTs. Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. People Learns to manage teams/stakeholders appropriately (utilizing their support). Brings forward sound proposals and shares lessons learned, without passing the blame. Anticipates setbacks and stays in control - takes criticism as intended for situations (not personally or toward particular individuals). Recovers quickly from problems and setbacks. Exhibits servant leadership and provides mentoring/coaching to junior TPLs, line functions and CMC team members to support their professional and personal growth. Leads by example and drives decisions. Generic Activities Leads CMC teams (in a matrix set up). Leads CMC team and other meetings (agendas, minutes, action tracker, moderation). Acts as link and conveys CMC topics between Global Project Team, CMC line functions and CMC boards to support decision making. Sets the CMC team and sub-teams objectives in line with the GPT / PoC Team objectives. Communicates transparently. Is able to communicate and adjust the message based on the audience (i.e., level of technical detail, etc.). Has financial and resource oversight, budget accountability/oversight. Takes responsibility for successes and failures of own and team's work, holds self and team accountable for outcomes (shifts priorities to ensure success). Leads DDs for assets in development. Is able to cope with time pressure and senior management exposure. Ideal Background Education (minimum/desirable): Advanced degree in life science, engineering or equivalent. Languages: Fluent in English Experience/Professional requirement: Successfully demonstrated several years (minimum of 2-3 years) of directly related experience as functional project leader and relevant experience as Associate TPL or equivalent. Has strong scientific/technical knowledge & understands technical development tasks for Small Molecules or Biologics (minimum) and Mixed Modalities (ideal). Is able to establish/maintain DS/DP/Device supply plan (in alignment with the clinical supply project lead). Has fundamental knowledge of GMP and regulatory requirements. Has a solid cross-functional knowledge (PK/PD, tox, clinical, commercial) regarding drug development. Manages end to end technical drug development and knowledge. Completed basic project management training. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Development Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Mengeš, Slovenia Alternative Location 2 Schaftenau, Austria Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary As part of International HEOR & PCO in International Value & Access, the Patient Centered Outcomes (PCO) HTA, TA Director within the HEOR TA teams, in partnership with HEOR leads co-leads the PCO reimbursement strategy that enables measurements of patient centered outcomes to support robust payer value propositions and evidence for HTAs, optimizing international access for prioritized Novartis assets. The PCO HTA TA Director will oversee one therapeutic area (e.g., CRM, immunology, oncology, or neurosciences) and their responsibility will span multiple assets/indications. Support and guidance to other members of the HEOR TA team for input or development of plans e.g. Health Technology Assessment Strategy Plans, Integrated Evidence Plans. The PCO HTA TA Director will be leading the HEOR Patient Centered Outcomes strategy within a Therapeutic Area and will contribute to the OnePCO Strategy through direct interface with the Clinical Development PCO Center of Excellence (PCO COE) when novel or disease-specific PCOs are required. In collaboration with regions and countries, The PCO HTA TA Director ensures that local PCO requirements are integrated into the PCO reimbursement strategy, and in the global and international evidence plans and PCO activities. Focus will be given to providing clear strategic rationale for and selection of health utility and other PROs for differentiation and translation to economic impact in partnership with HEOR. In addition, support the implementation of country-specific PCO evidence generation as needed to support access. The Director, HEOR PCO, will serve as an internal expert on health utility assessment activities. She/he will also lead health state valuation projects via development and management of Time Trade-Off (TTO) or Standard Gamble (SG) studies where appropriate. The PCO HTA TA Director will support HEOR TA on early scientific advice with HTAs e.g. EU HTA JSC and attend HTA meetings and/or support negotiations in collaboration with cross-functional and country team members. The Director will cultivate a strong partnership with team members from internal groups incl. Access, Clinical Development, PCO COE, AQS Biostat, Medical Affairs, and the International Commercial organization. In addition, PCO HTA TA Director will represent Novartis externally and ensure thought leadership in collaboration with external partners (e.g. industry consortiums e.g., ISPOR, ISOQOL, PRO/Utility experts). Internally, the Director ensures within HEOR TA and Novartis to drive understanding of HTA requirements for PCO, health utility assessment, and adoption of standards and best practices. About the Role Key Responsibilities: Co-leads with the HEOR TA lead the development, delivery and communication of a compelling PCO reimbursement strategy within the HTAP (Health Technology Assessment Strategy Plan), IPAS (Integrated Product Access Strategy), 1BP (One Brand Plan) and aligned with Integrated Evidence Plan (IEP). In partnership with the PCO COE, Global Program Teams, HEOR Leads, HTA Evidence Synthesis, Access, Medical Affairs, and AQS Biostat, ensures that the PCO measurement strategy includes patient reported outcomes and health utilities of relevance for international HTAs and payers into clinical development program. Participates in and co-leads projects on behalf of the OnePCO Alignment Forum to ensure PCOs critical for HTAs and payers are included in in clinical trials, non-interventional studies and real-world studies for select assets and coordinates with countries to ensure alignment on local HTA and payer needs. Drive understanding of HTA requirements for PCO, health utility assessment, and adoption of standards and best practices by key markets. Leads health state valuation projects via development and management of Time Trade-Off (TTO) or Standard Gamble (SG) studies where appropriate. Assists in scientific discussions with HTA agencies, particularly scientific advice from e.g. EU HTA JSC, NICE, CADTH…for PRO/PCO endpoints, MCIDs, and by preparing appropriate briefing documents and dossier by ensuring robust patient value proposition is included. Develops strategic scientific communication plan incl. submission and presentation of research in peer-reviewed journals and scientific/methodological congresses. Engages with external thought leaders, identify research collaboration/partnerships and represent Novartis with external stakeholders (academic institutions, HTA agencies…) to monitor and shape the external environment with respect to patient centred outcomes research and evolving evidentiary standards for utility endpoints and ensures awareness of these changes for Novartis. Lead above-brand research projects/initiatives to pilot innovative methodologies for value demonstration and elevate internal standards/best practices within International Value and Access and at Novartis with cross-functional partners. Essential requirements: 8+ years of Pharma Industry experience with 5+ years of experience in HEOR roles in pharmaceutical companies or consulting, with at least 3 years demonstrating specific leadership of health utility projects Advanced Degree in relevant field Experience in evaluating, developing and validating PRO/PCO instruments to meet HTA reimbursement requirements In-depth understanding of key patient centered outcomes measurement systems – e.g., EuroQoL, Quality Metric Short-Form measures, HUI etc. Ability to lead in a cross functional environment Ability to manage multiple priorities in rapidly changing environment Ability to work collaboratively to leverage other HEOR capabilities (strategy, regions, countries, COE PCO) Desirable requirements: Ph.D., M.D., MBA, MSc or equivalent. Strong external interfaces and network: KOLs, clinical research & scientific groups, payers, and policy organizations Experience in conducting and evaluating PCO measures from conceptualization through negotiation with international health authorities. Experience in HTA submissions Location: This role can be based in the UK, London but also in Dublin, Ireland or Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. About the Role About the role: The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. Key responsibilities: Lead a research team and collaborate with groups across BR Oncology Contribute to biomarker strategies and supervise translational experimental plans for various RLT drug discovery programs Design and conduct translational studies, dissect the biological mechanisms driving response and resistance to RLT, and develop rational drug combinations. Mentor and develop associates with various levels of experience Essential Requirements: Ph.D. in molecular, cellular, cancer biology or related fields. Minimum 2 years of Postdoctoral and/or industry experience in an Oncology/Cancer biology relevant field Recognised academic publication record Deep understanding of cancer cell biology, familiarity with innovative cell and molecular biology techniques. Excellent creative thinking and problem-solving skills, scientific curiosity. Proficiency in working collaboratively and flexibly on various projects Strong communication skills, at ease with conveying complex scientific concepts Desirable Requirements: Strong foundational knowledge and experience working on cell death mechanisms, experience in the field of DNA damage response and repair, radiobiology or RLT. Expertise in prostate cancer biology Proficiency with data mining and computational skills. Track record in managing a research team and scientific projects Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10065689 Nov 03, 2025 Switzerland Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten Teilnahme an den Herstellungsprozessen Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Kenntnisse über Technik und/oder Prozesse/Produkte Teamplayer mit gutem Teamgeist Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität Selbstmotivation und Lernfähigkeit Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) Gutes GMP-Verständnis Gute Kenntnisse in MS Office und Prozessleitsystemen Grundlegendes technisches Verständnis/der Automatisierung Warum Novartis: Um Menschen mit Krankheiten und ihren Familien zu helfen, braucht es mehr als nur innovative Wissenschaft. Es braucht eine Gemeinschaft intelligenter, engagierter Menschen wie Sie. Menschen, die zusammenarbeiten, sich gegenseitig unterstützen und inspirieren. Menschen, die gemeinsam Durchbrüche erzielen, die das Leben von Patienten verändern. Sind Sie bereit, gemeinsam eine bessere Zukunft zu gestalten? https://www.novartis.com/about/strategy/people-and-culture Vorteile und Vergütungen: In unserem Handbuch erfahren Sie alles darüber, wie wir Sie persönlich und beruflich fördern: https://www.novartis.com/careers/benefits-rewards Engagement für Vielfalt und Inklusion: Novartis hat sich zum Ziel gesetzt, ein hervorragendes, inklusives Arbeitsumfeld und vielfältige Teams zu schaffen, die die Patienten und Gemeinschaften, denen wir dienen, repräsentieren. Menschen und Kultur Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards