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Novartis AG

Novartis bietet innovative medizinische Lösungen an, um damit auf die sich verändernden Bedürfnisse von Patienten und Gesellschaften einzugehen. Novartis, mit Hauptsitz in Basel (Schweiz), verfügt über ein diversifiziertes Portfolio, um diese Bedürfnisse so gut wie möglich zu erfüllen: mit innovativen Arzneimitteln, Produkten für die Augenheilkunde und kostengünstigen generischen Medikamenten. Novartis ist das einzige Unternehmen mit weltweit führenden Positionen in diesen Bereichen.
Novartis bietet innovative medizinische Lösungen an, um damit auf die sich verändernden Bedürfnisse von Patienten und Gesellschaften einzugehen. Novartis, mit Hauptsitz in Basel (Schweiz), verfügt über ein diversifiziertes Portfolio, um diese Bedürfnisse so gut wie möglich zu erfüllen: mit innovativen Arzneimitteln, Produkten für die Augenheilkunde und kostengünstigen generischen Medikamenten. Novartis ist das einzige Unternehmen mit weltweit führenden Positionen in diesen Bereichen.
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27.07.2024

Novartis AG

Clinical Document Management: Technology Release Manager

  • Novartis AG

  • Basel

  • 27.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10014888 Jul 10, 2024 Switzerland Summary -Contributes, with appropriate oversight, to all relevant aspects of global clinical trial(s) activities to deliver study outcomes within schedule, budget, quality/compliance and performance standards. May lead specific aspects of global clinical trial(s). Core member of the Clinical Trial Team, Contributes to operational excellence through process improvement and knowledge sharing and/or provide inputs to clinical development process. -Applicable to Clinical Scientific Expert IIThe Clinical Scientific Expert II (CSE II) provides clinical and scientific support through all phases of a clinical study under the guidance of the (A)CD(M)D in compliance with Novartis processes, ICH GCP and regulatory requirements. This role applies the principles of clinical data review excellence and identifies clinical data insights to ensure data is scientifically plausible and to identify trends, signals and risks associated to trial endpoints and patient safety. The CSE II is a core member of the Clinical Trial Team (CTT). In addition, the CSE II supports/leads program level documents or activities as assigned. About the Role About the Role: Effective planning and delivery of releases of Novartis enterprise-wide clinical electronic document management systems (eDMS), partnering with technical vendors, internal IT and business stakeholders. Drives implementation of CDGM initiatives, projects and process improvement activities to enhance the planning and execution of releases of enterprise clinical eDMS at Novartis. o Act as CDGM point of contact for specific releases of eDMS, partnering with CDGM, IT (internal and external) and business stakeholders to plan and deliver releases to clinical eDMS, in line with Novartis technology roadmap, compliance and operational requirements. o Partner with CDGM and business stakeholders to understand business requirements, identify functionality gaps in eDMS and contribute to the planning of future releases through prioritisation of backlog items. o Contribute to activities to ensure efficient processes & integrations of systems with eDMS based on strong understanding of Novartis enterprise systems landscape and in line with compliance and business priorities. Serves as Subject Matter Expert for training materials, formal and informal processes and tracking tools for eDMS release management activities in collaboration with CDM Process team and other key stakeholders o Plan and contribute to agile working methodologies being applied during development cycles to prepare for releases and during post release hypercare period. o Owner or Contributor of activities related to release related Incident Management, Change Management and ongoing operations of the eDMS. o Support forecasting of internal resource allocations and vendor provided activities as part of eDMS release management. o Executes vendor oversight plan, monitors service metrics and identifies opportunities for improvement to the operating model. Acts as point of escalation for issues. o Provides support for inspections/audits, contributes to root cause analysis identification and creation/delivery of CAPAs. Role Requirements : Bachelor-s degree or equivalent and relevant industry experience Minimum of 6 years working in Pharmaceuticals, Lifesciences and Clinical Research with specific experience in managing releases of clinical document management, TMF and/or records & information management. Minimum 1 year of Veeva related hands on and provable experience in leading and planning of releases for Veeva and Internal business. Prior experience in Electronic Document Management systems, specifically in Clinical and Regulatory highly desired. Business relevant technical and working experience of eDMS systems like Veeva Clinical vault, RIM, Documentum D2LS or similar Knowledge of industrywide Electronic and Clinical Document Management systems and features Working knowledge of incident management and hyper care principles post releases Deep knowledge of Agile way of working with cross functional teams for releases Strong influencing and presentation skills. Ability to communicate effectively at all levels. High organisational awareness, including experience working in multi disciplinary teams, across cultures and geographies. Good negotiation, problem solving and conflict resolution skills; experience establishing trusted relationships with internal and external stakeholders. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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27.07.2024

Novartis AG

Associate Director, Strategic Projects

  • Novartis AG

  • Basel

  • 27.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10014450 Jul 24, 2024 Switzerland Summary To gain long-term value, it is vital that our Environmental Social Governance (ESG) efforts are embedded to ensure systemic change across the organization. You will collaborate with the internal community of Environment, Social, Governance (ESG) experts to develop and support key initiatives to position Novartis as a trusted leader in the pharmaceutical sector. This is a unique opportunity to shape Novartis- Sustainability strategy and work with senior leaders across the organization to drive long-term impact. You will report to the Head Strategy, Sustainability & ESG and supports key strategic initiatives across ESG dimensions and the cross-functional community of ESG exerts. About the Role Key responsibilities: Strategic initiatives: Support the Head Strategy, Sustainability & ESG with global initiatives in sustainability and ESG, e.g., lead and contribute to strategic projects and initiatives in the areas of health equity, social impact and environmental sustainability ESG 5-year roadmap: Contribute to the continued development and refinement of the 5-year sustainability and ESG strategy Governance processes & leadership support: Support key governance processes, owned by the ESG & Sustainability Office - incl. support the preparation of key leadership meetings (incl. ESG Committee, Executive-level decision board for ESG); act as Secretariat for the ESG Leaders Forum (one Executive-1 leader per unit/function responsible for Novartis cross-functional ESG strategy) and ESG Strategy LT (key stakeholders in units/functions) Commitment tracking: Lead ESG Commitments process oversight and tracking Capability building: Support training/learning concept and execution for the Board of Directors, Leadership, ESG Community and all-employee levels. Intelligence: Be on the forefront of knowledge in the sustainability and ESG space in the industry; support trend monitoring and benchmarking efforts; distill outputs and recommendations which enable informed decisions of top-level leaders External partnerships: Define and drive the sustainability & ESG engagement strategy for Novartis, with external stakeholders - including key events and memberships (Point of contact for external memberships) What you-ll bring to the role: Essential Criteria: Degree in Business, Engineering, Sustainability or Life Sciences (MBA a plus), or equivalent on-the-job experience. Strong knowledge of sustainability and ESG topics. Project and program management experience in strategic projects; management consulting background preferred (equal to associate, senior associate or project manager level) or other relevant work experience..... Ability to support and manage projects with high quality, interact with senior stakeholders and lead cross-functional project teams (internal stakeholders and external providers); strong attention to detail. Previous experience developing presentations for senior leaders, communicate and present clearly and make strategic recommendations in a complex matrix environment and to work at all levels of the organization, including senior stakeholders Desirable skills: Previous experience in the pharmaceutical industry (industry knowledge) Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential High proficiency in English - both written and oral Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Corporate Affairs Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area BD&L & Strategic Planning Job Type Full time Employment Type Regulär Shift Work No
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23.07.2024

Novartis AG

Data Science Innovation Fellow - Renal Translational Research

  • Novartis AG

  • Basel

  • 23.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012381 Jun 25, 2024 Switzerland Summary You are encouraged to apply for our Data Science Innovation Fellowship, which is a three-year post-doctoral research program to augment the way we approach drug discovery. The fellow will have the unique opportunity to train in data science and AI for biomedical research. As a fellow, you will apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will participate on a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying innovative data approaches in collaboration with a vibrant community of over 300 data scientists globally. The program provides a unique platform to access real-world, biomedical data at scale, rarely available in academia. Working with experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with options for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Your project will evolve practices in disease target identification and drug discovery through strengthening our ability to translate mechanistic insights gained from preclinical models to human kidney diseases. Developing a more sophisticated understanding of drug-kidney interactions is a crucial step towards creating successful drugs. To this end, you will use your quantitative background and leverage large-scale data to derive mechanistic insights from preclinical models relevant to human kidney biology and pathophysiology. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Advance methods and practices in spatial transcriptomics, including integrated histology image and transcriptomics analysis at scale. Explore novel multimodal and transfer learning analysis approaches towards advances in translatable kidney function assessment. Leverage a knowledgebase of hundreds of rodent studies to characterize the range of notable observations made on preclinical and patient kidney data. Uncover and seize opportunities for drug development by identifying relationships in large-scale datasets that can guide preclinical safety evaluations and novel target hypotheses. Collaborate closely with colleagues in toxicology, pathology, early discovery, and data sciences. Foster the role of data science and AI in drug discovery by implementing best practices and making data more accessible. Communicate research results to both internal and external audiences, such as scientific conferences and publications. Role requirements : PhD in a quantitative field (data science, machine learning, computer science, statistics) or life sciences, preferably with multidisciplinary background (chemoinformatics, bioinformatics, biomedical engineering, AI/ML in drug discovery or life sciences). PhD students in the last year of their thesis work, are eligible to apply. Solid understanding of statistics, machine learning and deep learning; Demonstrated knowledge of data visualization and exploratory analysis. Knowledge of Python and/or R, as well as machine learning/deep learning libraries. Experience with generative algorithms and explainable AI is a plus. Experience with reproducible data science tools and practices. Strong publication record or other scientific achievements (i.e. awards, patents, grants, public code repository) Highly effective analytical, communication, presentation, and organizational skills Passion for research and boundless curiosity. Team player. Strives for continuous learning (scientific and technical). #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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22.07.2024

Novartis AG

Data Science Innovation Fellow

  • Novartis AG

  • Basel

  • 22.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012275 Jul 09, 2024 Switzerland Summary Data Science Innovation Fellow Computed Aided Drug Design About the Role About the role We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in data science, AI/ML methodology, computer-aided drug discovery, cheminformatics and medicinal chemistry as well as pharmacokinetics, you will leverage state-of-the-art AI methodology and unique internal datasets to investigate multi-objective optimization in combination with generative models to accelerate drug discovery efforts. Start date: Autumn 2024 Key responsibilities As a Data Science Innovation Fellow, you will: Leverage proprietary data sets to evaluate and refine modern optimization algorithms in the context of generative chemistry. Apply a deep understanding of foundation models, including pre-trained and large language models, to leverage multi-objective optimization in generative AI applications. Collaborate with cross-functional teams in drug discovery projects; design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Explore the application of latest optimization, predictive and generative AI models to drug discovery and present your findings to the scientific community at conferences and in publications. Be part of a unique organization and work with an interdisciplinary team of highly accomplished scientists to push the frontiers of AI in drug discovery. Role requirements : PhD in computational chemistry, cheminformatics, computer science, mathematics, statistics or equivalent with a strong focus on machine-learning (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to drug discovery or small molecule design. Proficiency in Python and deep learning frameworks (e.g. Pytorch, Tensorflow, Keras), solid knowledge of statistics, machine learning and deep learning algorithms. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to re-imagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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20.07.2024

Novartis AG

Principal Scientist II Drug Discovery - Kidney Diseases (80-100%*)

  • Novartis AG

  • Basel

  • 20.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10006954 May 15, 2024 Switzerland Summary Location: Basel, Switzerland or Cambridge Mass, US Full time, onsite, #LI-onsite We are seeking an innovative and dynamic scientist with broad expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease. In this role, you will be responsible for driving research programs focused on delineating the key mechanisms involved in proteinuric kidney diseases and progressing new targets towards drug discovery. This individual will join the Renal Research team within Disease Area X (DAx) in Biomedical Research and report to the Head of Renal Research. About the Role Major accountabilities: Contribute to the Biomedical Research drug discovery process with the goal of progressing the development of new therapeutic options for patients with chronic kidney diseases. Formulate novel target hypothesis based on human disease mechanisms using deep and broad scientific expertise in renal physiology and pathophysiology of proteinuric kidney diseases. Design and execute in vitro and in vivo research plans to deliver high quality data-driven package and enable project decisions. Deliver impact to projects by identifying technical trends, both internal and external to your discipline. Lead multi-disciplinary project team(s) to portfolio transitions a/o decision milestones. Enable partnerships with data scientists, external partners, and individuals across Biomedical Research Disease Areas and platform functions. Develop and communicate project strategy, scientific vision, and data to key stakeholders. Manage and develop a team of research scientists. Develop and maintain external relationships/contacts. Essential requirements: A PhD and/or MD degree with postdoctoral experience and a minimum of three years of research in renal biology and physiology, preferably in the pharmaceutical or biotechnology industry. In-depth knowledge of kidney (patho-)physiology, including cultivation and analysis of complex renal cell-based platforms, e.g. 3D kidney organoids, primary 2D/3D endothelial or epithelial cell systems. Extensive “hands-on” experience and proven track-record in the use of a wide range of cellular, biochemical and genome editing methods and technologies to unravel complex cellular signaling pathways. Proficiency in “state of the art” computational and analytical approaches and comfortable with analyzing large scale genetic, NGS and single cell datasets. A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases. Ability to lead a project and plan ahead, be well organized and effectively use resources to execute experiments and deliver high quality data in a timely fashion. A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts. Experience in leading and mentoring associates and cross-functional teams. Excellent oral and written communication skills (in English) are essential. *Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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19.07.2024

Novartis AG

Data Science Innovation Fellow - Histopathology Foundation Models

  • Novartis AG

  • Basel

  • 19.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013211 Jun 26, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Over the period of three years, you will conceptualize and develop general-purpose Histopathology Foundation Models by leveraging thousands of whole-slide histopathology images from our internal data archives. You will be deeply embedded in our Computational Pathology and Artificial Intelligence & Computational Science teams and will work on large-scale representation learning approaches to build models that will lay the foundation of AI-enhanced pathology-based applications within Novartis. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Implement the state-of-the-art and design custom self- and weakly-supervised algorithms to build Foundation Models for histopathology data. Work as a team member on AI research projects independently, focusing on large-scale imaging data and practicing scientifically rigorous and reproducible methodology. Collaborate with other AI specialists, data architects, software engineers and pathologists within Biomedical Research on applications in the histopathology domain. Engage with diverse stakeholders in non-clinical as well as clinical settings. Build a bridge between academia and industry partners. Keep ahead of the latest developments in the field and bring curious and critical thinking to the team. Role requirements : PhD in Computer Science, Machine Learning, or a related field with a focus on image and vision applications (PhD students in the last year of their thesis work, are eligible to apply). Strong programming experience in python and proficiency in at least one main deep learning framework (PyTorch/TensorFlow/JAX). Proven experience in implementing state-of-the-art machine/deep learning algorithms. Scientific publications in AI/ML conferences and/or in journals with a focus on computational biology/medicine. Ability to clearly communicate technical concepts to a variety of audiences, including scientists, engineers, and subject matter experts from other domains. Familiarity with working on high-performance computing systems and/or cloud computing environments and version controlling is nice to have. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No Apply to Job(link is external)
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16.07.2024

Novartis AG

Strategy Director, Clinical Development

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10010244 Jul 04, 2024 Switzerland Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for a Strategy Director, Clinical Development. About the Role The purpose of the Strategy Director Clinical Development will be to support the crafting and execution of portfolio strategy and clinical program/functional excellence by actively partnering with the Head of Portfolio Strategy and Operations, Clinical Development Functional Heads, Head of Clinical Workforce Insights, Head of Program Capability and Quality, Head of Advanced Methods and Centers of Excellence, and Head of Data Design and Clinical Innovation. The Strategy Director may deputize for Head of Portfolio Strategy and Operations within Clinical Development and with a wide range of cross-functional teams. What you will be doing: Undertake diagnostics, study and analysis as required, suggest recommendations and drive resultant actions as approved. Continuously looks for new and better ways to deliver Clinical Development (CD) agenda. Prepares content for pivotal initiatives on behalf of the Head of Clinical Development/Head Portfolio Strategy & Operations. Support the streamlining and provide governance co-leadership for the Head Portfolio Strategy and Operations CD, ensuring consistent messaging across various governance forums (DevLT, CD LT). Support the build of the CD organization, creating and tracking meticulous and quantifiable objectives and communications; to support CD embedding best in class approaches to clinical development while growing deep therapeutic expertise. Lead on the benchmarking of CD activities at Novartis vs. peers Helps shape, influence and lead on functional strategy related activities and requests e.g., cross functional activities such as SRC governance with Global Medical Affairs, new initiatives to strengthen Development and CD, requests from Strategy Program Portfolio Operations. Represents the Head of Portfolio Strategy and Operations with cross-functional teams and within Clinical Development where needed. Supports the annual Clinical Development Strategy Review and objectives setting in collaboration with the CD Head, Clinical Development Heads and CD functional heads. Helps maintain updated CD program and above program reviews for, e.g., IMB, DevLT partnering closely with functional leaders. Ensure connectivity with global line functions to establish CD leadership amongst related functional teams, to ensure objectives are met, as mandated by DevLT/IMB. For example, work with Methods Head to establish IEP review process, work with Program Excellence & Capability Head to establish and embed Integrated Data Review, work with Data Design & Clinical Innovation head to help establish protocol AI. Supports the Head of Portfolio Strategy & Operations, to establish relationships and reinforce CD as single point leader for clinical programs, including Global Clinical Operations, Analytics, and Global Medical Affairs. Provides analytic insights into potential S&G, M&A and BD&L initiatives to evaluate from clinical perspective new opportunities Responsible for effective internal and external communication co-ordination on initiatives led by CD that warrant white papers or other external communication, e.g. updates to DevLT, IMB, Leadership forums. Navigates complexity and drives effectiveness across the function and in collaboration with other functions in Novartis Work closely with Head of Operational Excellence, Clinical Development Function Heads, head of Clinical Workforce Insights, Head of Capabilities, Engagement Lead. What you will bring to the role: Master degree or equivalent advanced degree or equivalent education/degree in life science/healthcare preferred (MD, PhD) -5 years people and matrix management required. Global people management experience desirable. Strong relationship builder and communicator with experience leading diverse work teams, driving program excellence, engaging functional partners Previous work and leadership in international and multidisciplinary drug development teams Strong knowledge of drug development strategy, Novartis experience in this area is preferred. Strong planning and project management skills Organizational awareness, including meaningful experience working cross-functionally and in global teams. Strong written & verbal communication coupled with excellent problem-solving, negotiation and conflict resolution skills. Strong communication skills with excellence understanding of presentation tools Experience in Consulting/Banking (Healthcare focus) preferred. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Strategy Director, Clinical Development

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10010244 Jul 19, 2024 Switzerland Summary When we put our heads together, we can do brilliant work. And when we do brilliant work, we can achieve remarkable things for patients as we positively transform healthcare. We are looking for a Strategy Director, Clinical Development. About the Role The purpose of the Strategy Director Clinical Development will be to support the crafting and execution of portfolio strategy and clinical program/functional excellence by actively partnering with the Head of Portfolio Strategy and Operations, Clinical Development Functional Heads, Head of Clinical Workforce Insights, Head of Program Capability and Quality, Head of Advanced Methods and Centers of Excellence, and Head of Data Design and Clinical Innovation. The Strategy Director may deputize for Head of Portfolio Strategy and Operations within Clinical Development and with a wide range of cross-functional teams. What you will be doing: Undertake diagnostics, study and analysis as required, suggest recommendations and drive resultant actions as approved. Continuously looks for new and better ways to deliver Clinical Development (CD) agenda. Prepares content for pivotal initiatives on behalf of the Head of Clinical Development/Head Portfolio Strategy & Operations. Support the streamlining and provide governance co-leadership for the Head Portfolio Strategy and Operations CD, ensuring consistent messaging across various governance forums (DevLT, CD LT). Support the build of the CD organization, creating and tracking meticulous and quantifiable objectives and communications; to support CD embedding best in class approaches to clinical development while growing deep therapeutic expertise. Lead on the benchmarking of CD activities at Novartis vs. peers Helps shape, influence and lead on functional strategy related activities and requests e.g., cross functional activities such as SRC governance with Global Medical Affairs, new initiatives to strengthen Development and CD, requests from Strategy Program Portfolio Operations. Represents the Head of Portfolio Strategy and Operations with cross-functional teams and within Clinical Development where needed. Supports the annual Clinical Development Strategy Review and objectives setting in collaboration with the CD Head, Clinical Development Heads and CD functional heads. Helps maintain updated CD program and above program reviews for, e.g., IMB, DevLT partnering closely with functional leaders. Ensure connectivity with global line functions to establish CD leadership amongst related functional teams, to ensure objectives are met, as mandated by DevLT/IMB. For example, work with Methods Head to establish IEP review process, work with Program Excellence & Capability Head to establish and embed Integrated Data Review, work with Data Design & Clinical Innovation head to help establish protocol AI. Supports the Head of Portfolio Strategy & Operations, to establish relationships and reinforce CD as single point leader for clinical programs, including Global Clinical Operations, Analytics, and Global Medical Affairs. Provides analytic insights into potential S&G, M&A and BD&L initiatives to evaluate from clinical perspective new opportunities Responsible for effective internal and external communication co-ordination on initiatives led by CD that warrant white papers or other external communication, e.g. updates to DevLT, IMB, Leadership forums. Navigates complexity and drives effectiveness across the function and in collaboration with other functions in Novartis Work closely with Head of Operational Excellence, Clinical Development Function Heads, head of Clinical Workforce Insights, Head of Capabilities, Engagement Lead. What you will bring to the role: Master degree or equivalent advanced degree or equivalent education/degree in life science/healthcare preferred (MD, PhD) ≥5 years people and matrix management required. Global people management experience desirable. Strong relationship builder and communicator with experience leading diverse work teams, driving program excellence, engaging functional partners Previous work and leadership in international and multidisciplinary drug development teams Strong knowledge of drug development strategy, Novartis experience in this area is preferred. Strong planning and project management skills Organizational awareness, including meaningful experience working cross-functionally and in global teams. Strong written & verbal communication coupled with excellent problem-solving, negotiation and conflict resolution skills. Strong communication skills with excellence understanding of presentation tools Experience in Consulting/Banking (Healthcare focus) preferred. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

QC Analyst II.

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10014886 Jul 09, 2024 Switzerland Summary ~Unterstützt alle GxP-Aktivitäten in der Qualitätsabteilung. Verwaltet Qualitätssysteme / Prozesse einschließlich Dokumentation, Metriken und Überwachung von Aktionen. ~ Unterstützt die Etablierung von Qualitätsbetriebsprozessen. Führt routinemäßige GxP-Compliance/ Operative Aktivitäten gemäß den Novartis Qualitätsstandards durch. Unterstützt Qualitätsprojekte und -initiativen. About the Role Diese Stelle ist auf 2 Jahre ausgeschrieben. Ihr Verantwortungsbereich: Behält die geltenden Standard Operating Procedures (SOPs), GxP-konforme Dokumentationen und Aufzeichnungen innerhalb des Novartis Qualitätsmanagementsystems bei. Gewährleistet die Integrität aller Qualitätssicherungsdatensätze und -daten, soweit anwendbar, und die Zusammenarbeit des eigenen Teams mit anderen Funktionen und Abteilungen. Gewährleistet ein angemessenes Bildungsniveau, GxP-Kenntnisse. Aktualisierung und Verwaltung relevanter Informationen in elektronischen Systemen (z.B. Change Control, Dokumentation, Training). Weiterverfolgung und Überwachung von z. B. CAPAs, Maßnahmen, Metriken, Qualitätsplan). Unterstützt Qualitätsaudits und Inspektionen durch die Gesundheitsbehörde. Meldung von technischen Beschwerden / unerwünschten Ereignissen / Sonderfallszenarien im Zusammenhang mit Novartis-Produkten innerhalb von 24 Stunden nach Erhalt Verteilung von Vermarktungsmustern (falls zutreffend) Was Sie zur Rolle mitbringen: QC/ QA in der pharmazeutischen Industrie/Biotechnologie mit Umweltüberwachung und Reinheitszonen QA (Qualitätssicherung) und Qualitätskontrolle (Qc) Prüfung GMP-Verfahren Qualitätsmaßstäbe Technologisches Know-how und technologische Intelligenz Englische Sprache Warum Novartis? Über 766 Millionen! - so viele Leben haben wir im Jahr 2021 mit unseren Produkten erreicht. Und während wir darauf stolz sind, stellen wir uns ständig die Frage: Wie können wir in einer Welt des digitalen und technologischen Wandels noch mehr Leben verbessern und verlängern? Wir glauben, dass an der Schnittstelle von medizinischer Wissenschaft und digitaler Innovation neue Erkenntnisse, Perspektiven und bahnbrechende Lösungen gefunden werden können und dass ein vielfältiges, gleichberechtigtes und integratives Umfeld zu neuen Arbeitsweisen inspiriert. Wir sind davon überzeugt, dass unser Potenzial in einer von Integrität, Neugier und Flexibilität geprägten Kultur gedeihen und wachsen kann. Und wir können neu erfinden, was möglich ist, wenn wir mit Mut zusammenarbeiten, um die schwierigsten medizinischen Herausforderungen der Welt offensiv und ehrgeizig anzugehen. Denn das größte Risiko im Leben ist das Risiko, es nie zu versuchen! Stellen Sie sich vor, was Sie hier bei Novartis tun könnten! Engagement für Vielfalt & Inklusion Novartis ist bestrebt, ein hervorragendes, integratives Arbeitsumfeld und ein vielfältiges Team aufzubauen, das die Patienten und Gemeinschaften, denen wir dienen, repräsentiert. Zugänglichkeit und Unterbringung Der Novartis Konzern ist bestrebt, mit allen Personen zusammenzuarbeiten und ihnen angemessene Vorkehrungen zu bieten. Wenn Sie aufgrund einer Erkrankung oder Behinderung eine angemessene Vorkehrung für einen Teil des Einstellungsverfahrens benötigen oder um detailliertere Informationen über die wesentlichen Funktionen einer Stelle zu erhalten, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihrer Anfrage und Ihre Kontaktdaten mit. Bitte geben Sie in Ihrer Nachricht die Nummer der Stellenausschreibung an. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Stelle nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber in Verbindung bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, werden Sie hier Mitglied des Novartis Netzwerks: https://talentnetwork.novartis.com/en\_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH028) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Befristet (Befristet) Shift Work No
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16.07.2024

Novartis AG

Principal Scientist - Radioligand Therapy (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID REQ-10010495 Jun 11, 2024 Switzerland Summary Novartis' Biomedical Research division is our Innovation engine. Within our ground-breaking Radioligand Therapy Labs in our Oncology division we have ambitions to transform the lives of millions of people living with cancer and focus in powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Oncology Research department at Novartis Institutes for Biomedical Research is recruiting for a Ph.D. level Principal Scientist with a strong background and track record in cancer cell biology. Expertise in the field of radioligand therapy development and/or radiobiology would be desirable. About the Role The candidate will join an Oncology Drug Discovery Research group located in Basel/Switzerland and will be responsible to lead projects in the areas of oncology drug discovery and radioisotope-based therapies. This is an excellent opportunity to join a world class research team at NIBR in Basel, Switzerland. The successful candidate exhibits strong leadership skills, a collaborative team spirit, excellent communication skills and willingness to pro-actively interact across the global organization. Excellent mentoring and coaching skills will be a necessary asset to develop team members scientifically and professionally. Your responsibilities will include: · Design and manage in vivo studies to support the preclinical evaluation of novel radioligand therapies (efficacy, biodistribution, PET/SPECT imaging and MoA studies) · Collaborate with cross-functional project teams (chemistry, clinical, safety, pathology etc) to advance novel radioligand therapies to the clinic. · Work effectively with CROs and academic institutes. · Guide, supervise and develop team members across functions. · Present concepts and projects in a clear, scientifically sound and data-driven, objective manner in different settings and venues. · Work closely with multiple teams across expertise groups within Oncology and across departments in the global organization (e.g. BD&L, Global Drug Development, Commercial). What will you bring to the role: Ph.D. in pharmacology and/or cell biology with a minimum of 3 years additional experience in biomedical research (either industry or academia). Strong background in cancer biology and a track record of scientific accomplishment at high standards. Considerable experience performing and managing in vivo oncology studies (efficacy, PK/PD, ex vivo analysis by flow cytometry, IF/IHC, RNA Seq etc). Highly collaborative team player that enjoys working across multi-disciplinary team. Background in radioligand therapy development/radiobiology is highly desirable - Strong experience in drug development would be favorable. Excellent communication and presentation skills in English. Self-motivated, proactive, and able to work independently. * This position is eligible for 80-100%* working time, however, some restrictions on flexible working options may apply and will be discussed during interview if applicable. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

Principal Scientist - Drug Discovery Glomerulonephritis (80-100%*)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 80-100%

Festanstellung 80-100%

Basel

Job ID 390562BR Jun 11, 2024 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Immunology (IMM) department is accommodated within the Biomedical Research department of Novartis and works in collaboration with colleagues from Novartis Research and Development on several therapeutic areas with high unmet need, including autoimmune and inflammatory kidney diseases. Using a diverse array of approaches and ground breaking technology, IMM strives to develop drugs that improve the lives of individuals suffering from autoimmune and inflammatory kidney diseases for which there is currently no cure. At Novartis we have a bold ambition to transform the lives of millions of people living with such diseases. About the Role We are seeking an innovative, independent and dynamic Principal Scientist with broad expertise in nephrology and immunology to join a discovery biology team focused on developing innovative therapeutic agents in the area of glomerulonephritis. Your responsibilities will include: Contribute to the Biomedical Research drug discovery process with the goal to discover and develop novel therapeutic treatment options for patients with glomerulonephritis. Lead drug discovery projects in the renal disease space, propose and champion new targets and novel approaches for disease treatment. Contribute to translational research activities and mechanism of action studies to support ongoing clinical development programs Design and execute in vitro and in vivo research plans to evaluate targets modulating glomerulonephritis indications. Engage in interdisciplinary research requiring the application of specialized scientific knowledge and advanced laboratory techniques, in particular in vitro and in vivo models of glomerular diseases. Collaborate with other scientists in a global matrixed dynamic environment fostering innovation and advance project activities. Develop and maintain external relationships/contacts. What you will bring to the role: A PhD and/or MD degree with Postdoctoral experience and a minimum of three years of research in renal biology and/or immunology, preferably in the pharmaceutical / biotechnology industry or academia. In-depth knowledge of pathophysiology of autoimmune and inflammatory glomerular diseases, especially around the role of pathogenic autoantibodies in disease i.e. expert in B cell biology, immune complex mediated renal diseases, autoantibody mediated effector function and inflammatory pathways in renal diseases. A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases. A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts. Excellent oral and written English communication skills, with an ability to effectively interact with people in a dynamic matrix environment, both internally and externally Experience in leading and mentoring associates and cross-functional teams *Restrictions on working flexibility may apply to this position and can be discussed at interview as required Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Ground Services Manager

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10011036 Jun 21, 2024 Switzerland Summary Location: Basel, Switzerland #LI-Hybrid The Ground Services Manager plays a critical role in the efficient and effective operation of ground services for JAPAT, so this role requires a strong aviation background, extensive leadership experience, and a service-oriented mindset. Reporting directly to the Accountable Manager (AM), the Ground Services Manager is responsible for leading the ground operations team and ensuring seamless coordination between ground operations and all other processes involved in the JAPAT flight activities. About the Role Key Responsibilities: Team Leadership: Lead, mentor, and develop the ground operations team, fostering a positive culture of accountability, teamwork and continuous improvement. Provide guidance and support to the team members, ensuring they have the required resources and learning, training and development opportunities to perform their roles effectively. Foster a positive team culture by effective communication, empowerment of all team members to work independently and efficiently, recognizing and valuing their contributions and identify and resolve conflicts before they aggravate. Stakeholder Management: Serve as the primary point of contact for the Novartis booking agents, providing personalized assistance and ensuring their needs are met before and after flights. Maintain strong communication channels with all JAPAT internal stakeholders to coordinate ground services and address any operational issues or concerns. Cooperation with the Nominated Person Flight Operations (NPFO) to liaise on all processes between both entities as well as with the Nominated Person Safety and Compliance (NPSC) for all safety related matters and to address non compliances and/or root cause analysis (CAPAs). Vendor Coordination: Liaise with ground support vendors, including Fixed Base Operators (FBOs), fueling companies, and deicing providers, to ensure timely and efficient service delivery. Pre-flight and Post-flight Operations: Oversee the JAPAT pre-flight and post-flight processes, to ensure a smooth and enjoyable travel experience for passengers and follow up on all service-related deviations (in close collaboration with the NPFO and the Cabin Attendant Manager). Process Improvement: Identify opportunities for process improvement and implement strategies to enhance the efficiency and effectiveness of ground service operations as well as develop and monitor metrics to measure the performance of ground services and identify areas for improvement. Essential Requirements: Bachelor's degree in Aviation Management, Business Administration, or a related field Experience in aviation operations, with a strong understanding of ground handling procedures and regulations as well as aviation safety regulations and best practices Proven leadership experience, with the ability to effectively lead and develop a team of aviation professionals Excellent communication skills and ability to interact professionally with internal and external stakeholders at all levels Strong service mindset, with a focus on delivering exceptional customer service and ensuring passenger satisfaction paired with a can-do-attitude and effective problem-solving skills Proficiency in Microsoft Office suite and aviation-specific software systems Flexibility to work irregular hours, including evenings, weekends (as needed) and willingness to travel occasionally for training and professional development opportunities Proficiency in English (written and spoken), knowledge of German is a plus Desirable Requirements: Business aviation and flight dispatch background Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. Thrive Together (novartis.com) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Corporate Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Drug Product Project Leader - Parenterals (m/f/d)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013083 Jul 08, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Join our team in Pharmaceutical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical experience. Demonstrated expertise in formulation development (parenteral, aseptic, solution, and/or suspension) and manufacturing process development Experience with aseptic Drug Product manufacturing of parenterals, including process transfer, scale-up and QbD design. Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Knowledge of regulatory requirements in parenteral Drug Product development and manufacturing is a plus. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Drug Product Project Leader - Parenterals (m/f/d)

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013083 Jul 09, 2024 Switzerland Summary Location: Basel, Switzerland Role Purpose: Join our team in Pharmaceutical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Apply to Job(link is external) Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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16.07.2024

Novartis AG

Data Science Innovation Fellow, Structural Bioinformatics

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10010397 Jun 10, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in computational and data science, AI/ML methodology, protein science, high throughput screening as well as modeling/computer-aided drug design, you will leverage state-of-the-art AI methodology and unique internal datasets to model protein-protein and protein-ligand interactions and drive drug discovery efforts. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage large, proprietary data sets to fine-tune innovative AI models for protein-ligand structure predictions. Design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Collaborate with cross-functional teams and apply the latest structural AI models to real world drug discovery projects. Explore the application of the latest structure-based AI methods to drug discovery workflows and present your findings to the scientific community at BR (Biomedical Research) Role requirements : PhD in computational biology, cheminformatics, structural biology or equivalent, with extensive computational experience (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to protein modeling, drug discovery or small molecule design. Strong background in structural AI methods (e.g., Alphafold, Rosetta Fold, Openfold). Proficiency in Python and machine learning libraries (e.g., TensorFlow, PyTorch, Jax) in high performance computing/cloud computing environments (e.g. AWS). Experience with protein-ligand interaction prediction and drug discovery workflows. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 15 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow - Renal Translational Research

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012381 Jun 19, 2024 Switzerland Summary You are encouraged to apply for our Data Science Innovation Fellowship, which is a three-year post-doctoral research program to augment the way we approach drug discovery. The fellow will have the unique opportunity to train in data science and AI for biomedical research. As a fellow, you will apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will participate on a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying innovative data approaches in collaboration with a vibrant community of over 300 data scientists globally. The program provides a unique platform to access real-world, biomedical data at scale, rarely available in academia. Working with experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with options for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Your project will evolve practices in disease target identification and drug discovery through strengthening our ability to translate mechanistic insights gained from preclinical models to human kidney diseases. Developing a more sophisticated understanding of drug-kidney interactions is a crucial step towards creating successful drugs. To this end, you will use your quantitative background and leverage large-scale data to derive mechanistic insights from preclinical models relevant to human kidney biology and pathophysiology. Start date: Winter 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Advance methods and practices in spatial transcriptomics, including integrated histology image and transcriptomics analysis at scale. Explore novel multimodal and transfer learning analysis approaches towards advances in translatable kidney function assessment. Leverage a knowledgebase of hundreds of rodent studies to characterize the range of notable observations made on preclinical and patient kidney data. Uncover and seize opportunities for drug development by identifying relationships in large-scale datasets that can guide preclinical safety evaluations and novel target hypotheses. Collaborate closely with colleagues in toxicology, pathology, early discovery, and data sciences. Foster the role of data science and AI in drug discovery by implementing best practices and making data more accessible. Communicate research results to both internal and external audiences, such as scientific conferences and publications. Role requirements : PhD in a quantitative field (data science, machine learning, computer science, statistics) or life sciences, preferably with multidisciplinary background (chemoinformatics, bioinformatics, biomedical engineering, AI/ML in drug discovery or life sciences). PhD students in the last year of their thesis work, are eligible to apply. Solid understanding of statistics, machine learning and deep learning; Demonstrated knowledge of data visualization and exploratory analysis. Knowledge of Python and/or R, as well as machine learning/deep learning libraries. Experience with generative algorithms and explainable AI is a plus. Experience with reproducible data science tools and practices. Strong publication record or other scientific achievements (i.e. awards, patents, grants, public code repository) Highly effective analytical, communication, presentation, and organizational skills Passion for research and boundless curiosity. Team player. Strives for continuous learning (scientific and technical). #DSIF How to apply Please submit your CV and cover letter by July 15 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow, Multimodal Neuroscience

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013277 Jun 26, 2024 Switzerland Summary 275 million years of life were prematurely lost due to neurological conditions in 2021. We are now looking for a Data Science Innovation Fellow to join us in our mission to develop disease-modifying treatments for some of the most common, debilitating neurodegenerative diseases. Leveraging rich real-world data from patients, you will develop cutting-edge multimodal approaches to investigate neurodegenerative disease progression and work together with our drug discovery teams to incorporate data science insights into our programs. This applied 3-year Data Science Innovation Fellowship program is set to change the way we approach drug discovery, offering fellows a unique chance to train in Data Science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in data science and AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data Science and AI and shape the future of drug discovery! Start date: Autumn 2024 About the Role Location: Basel #LI Hybrid About the role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage your curiosity and creativity to investigate complex biological problems in drug discovery of neurodegenerative disease. Design computational workflows to integrate real-world data from patients with molecular readouts. Apply cutting-edge multimodal AI approaches across multiple data modalities, incl. clinical data, imaging, genetics, omics-, metabolomics. Empower our teams by collaborating with interdisciplinary groups, presenting findings, and communicating complex concepts to stakeholders. Role requirements PhD in a statistical or quantitative field such as computer science, data science, computational biology, mathematics, statistics, or physics, or a related field (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying machine learning to biomedical or biological problems, and experience in data manipulation, cleaning, and preprocessing techniques. Experience working with multiple data modalities or omics data (genomics, proteomics, transcriptomics, etc.) is a plus. Strong understanding of statistical analysis, mathematical modeling, and machine learning algorithms. Proficiency in Python, R with experience in frameworks and libraries commonly used in machine learning and AI, such as TensorFlow, PyTorch. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow - Histopathology Foundation Models

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10013211 Jun 26, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! Over the period of three years, you will conceptualize and develop general-purpose Histopathology Foundation Models by leveraging thousands of whole-slide histopathology images from our internal data archives. You will be deeply embedded in our Computational Pathology and Artificial Intelligence & Computational Science teams and will work on large-scale representation learning approaches to build models that will lay the foundation of AI-enhanced pathology-based applications within Novartis. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Implement the state-of-the-art and design custom self- and weakly-supervised algorithms to build Foundation Models for histopathology data. Work as a team member on AI research projects independently, focusing on large-scale imaging data and practicing scientifically rigorous and reproducible methodology. Collaborate with other AI specialists, data architects, software engineers and pathologists within Biomedical Research on applications in the histopathology domain. Engage with diverse stakeholders in non-clinical as well as clinical settings. Build a bridge between academia and industry partners. Keep ahead of the latest developments in the field and bring curious and critical thinking to the team. Role requirements : PhD in Computer Science, Machine Learning, or a related field with a focus on image and vision applications (PhD students in the last year of their thesis work, are eligible to apply). Strong programming experience in python and proficiency in at least one main deep learning framework (PyTorch/TensorFlow/JAX). Proven experience in implementing state-of-the-art machine/deep learning algorithms. Scientific publications in AI/ML conferences and/or in journals with a focus on computational biology/medicine. Ability to clearly communicate technical concepts to a variety of audiences, including scientists, engineers, and subject matter experts from other domains. Familiarity with working on high-performance computing systems and/or cloud computing environments and version controlling is nice to have. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Data Science Innovation Fellow

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10012275 Jun 18, 2024 Switzerland Summary Data Science Innovation Fellow Computed Aided Drug Design About the Role About the role We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you-ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in data science, AI/ML methodology, computer-aided drug discovery, cheminformatics and medicinal chemistry as well as pharmacokinetics, you will leverage state-of-the-art AI methodology and unique internal datasets to investigate multi-objective optimization in combination with generative models to accelerate drug discovery efforts. Start date: Winter 2024 Key responsibilities As a Data Science Innovation Fellow, you will: Leverage proprietary data sets to evaluate and refine modern optimization algorithms in the context of generative chemistry. Apply a deep understanding of foundation models, including pre-trained and large language models, to leverage multi-objective optimization in generative AI applications. Collaborate with cross-functional teams in drug discovery projects; design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Explore the application of latest optimization, predictive and generative AI models to drug discovery and present your findings to the scientific community at conferences and in publications. Be part of a unique organization and work with an interdisciplinary team of highly accomplished scientists to push the frontiers of AI in drug discovery. Role requirements : PhD in computational chemistry, cheminformatics, computer science, mathematics, statistics or equivalent with a strong focus on machine-learning (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to drug discovery or small molecule design. Proficiency in Python and deep learning frameworks (e.g. Pytorch, Tensorflow, Keras), solid knowledge of statistics, machine learning and deep learning algorithms. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 15 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and tru ste d medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people and culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Early Talent (Fixed Term) Shift Work No
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16.07.2024

Novartis AG

Clinical Development Medical Director - Oncology

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10003632 Jul 08, 2024 Switzerland Summary -Leads the strategic and operational planning and management of the assigned clinical program(s) from an end-to-end clinical operations perspective. Complete oversight of budget and resource allocation for the assigned programs. Drives operational excellence through process improvement and knowledge sharing across the function. Enables an empowered organization which can navigate in a matrix environment and adjust quickly to business needs. About the Role Novartis is deeply committed to transforming the lives of people living with solid tumors. We believe that anyone living with these conditions has the right to a life free from pain, free from symptoms and free from disease - this is our vision for the future. Our mission is to reimagine medicine to extend and improve peoples lives - and our overall company strategy to achieve this is to Focus Novartis as a leading medicine company powered by data science and advanced therapy platforms such as Radioligand Therapy (RLT). Novartis has become the industry leader in RLT after the acquisition of Advanced Accelerator Applications (AAA) and Endocyte in 2018, together with other significant investments to advance radioligand research. Novartis Oncology is now developing a wide range of targeted RLTs, and precision Radioligand Imaging (RLI) agents, for oncology with a rich pipeline targeting multiple tumor types through a phenotypic precision medicine approach. Nuclear Medicine (NM) expertise is key for Novartis Oncology to expand RLT and supportive RLI agents in a sustainable manner. The Clinical Development Medical Director (CDMD) is responsible for leading the planning and management of the assigned RLI clinical program(s) to support the RTL trials from an end-to-end clinical development perspective. As CDMD, you will have oversight of assigned programs and drive execution of the plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. Your responsibilities as a Nuclear Medicine expert will include: Providing clinical leadership and strategic medical input for all clinical results in the assigned project or section of a clinical program Leading development of RLI related clinical sections of trial and program level regulatory documents Driving execution of the program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a Nuclear Medicine physician specialist, supporting the (Sr.) GPCH or CDH in interactions with external and internal partners and decision boards Contribute to the publication strategy of RLI/RLT compounds from the scientific standpoint May work with NIBR (Novartis Institute of Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Commitment to Diversity & Inclusion: : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements : What you'll bring to the role: Nuclear medicine Physician/Medical Doctor Sophisticated knowledge and clinical training in oncology PET; Clinical practice experience - 5 years preferred. Experience in Clinical Trials with a PET component Experience with Radioligand therapy A consistent track record to interpret, discuss and present data relating to clinical trial(s) with a Nuclear Medicine component Demonstrated ability to establish effective scientific partnerships with key partners Solid understanding of GCP, clinical trial design, statistics, regulatory and clinical development processes Some restrictions to flexible working models may apply and will be discussed at interview if applicable Why consider Novartis? 769 million lives were touched by Novartis medicines in 2023, and while we-re proud of this, we know there is so much more we could do to help improve and extend people-s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world-s toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 India Alternative Location 2 United Kingdom Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

Clinical Development Medical Director - Immunology

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%Management / Kader

Festanstellung 100%

Management / Kader

Basel

Job ID REQ-10008803 Jul 10, 2024 Switzerland Summary As the Clinical Development Medical Director (CDMD) Immunology you will lead clinical teams dedicated to autoimmune rheumatic disease development programs in indications of lupus, including both systemic lupus erythematosus and lupus nephritis, through all study phases from inception/design to database lock and read-out. Core responsibilities include planning and management of the assigned clinical projects(s) from an end-to-end clinical development perspective. Together with your team, you will drive execution of the clinical development plan. You will harness the strengths of a diverse team and create a collaborative and inclusive work environment You are eager to empower your team members, in a complex matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Lead development of clinical sections of trial and program level regulatory documents Drive execution of the program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors, and regional/country medical associates Support the Global Program Clinical Head in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety colleagues Support the Clinical Development Head by providing medical input into the Clinical Development Plan, Integrated Development Plan and Clinical Trial Protocol reviews. and contributing to development of disease clinical standards for new disease areas As a medical specialist, supporting the GPCH or CDH in interactions with external and internal partners and decision boards May work with Novartis Biomedical Research/ Translational Medical Sciences to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with other medical matters, as needed Key performance indicators: Timely, efficient and quality execution of trials and trial related activities within assigned clinical program(s) within budget, and in compliance with quality standards Appropriate funding and resourcing for assigned clinical program(s) Adherence to Novartis policy and guidelines and external regulations Minimum Requirements: MD or equivalent medical degree is required, in addition to a proven track record of clinical experience in and scientific contributions to your field of expertise Training or working experience in one or more of the following: 1) rheumatology or clinical immunology; 2) lupus clinical trials (systemic lupus erythematous and/or lupus nephritis; 3) B cell-depleting biologics 3+ years minimum in clinical research or drug development in immunology/inflammation Working knowledge in the area of Immunology and Inflammation with ability to interpret, discuss and present efficacy (clinical, biomarker) and safety data relating to clinical trials Understanding of GCP, clinical trial design, statistics, and regulatory and clinical development processes. Availability of, and readiness to leverage scientific and clinical networks to establish scientific partnerships with key collaborators Ability to confidently lead independent data monitoring committees and phase 2b/3 advisory boards Skills: Budget Management Clinical Research Clinical Trials Coaching Cross-Functional Teams Lifesciences People Management Risk Management Risk Monitoring Languages : English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ireland Alternative Location 2 United Kingdom Alternative Location 3 Spain Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No
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16.07.2024

Novartis AG

AD Product Manager, Drug Candidate Selection Software Applications

  • Novartis AG

  • Basel

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10008985 Jun 21, 2024 Switzerland Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process - both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams- culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
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14.07.2024

Novartis AG

Data Science Innovation Fellow, Structural Bioinformatics

  • Novartis AG

  • Basel

  • 14.07.2024

  • Festanstellung 100%

Festanstellung 100%

Basel

Job ID REQ-10010397 Jul 09, 2024 Switzerland Summary We are thrilled to open applications for our Data Science Innovation Fellowship. This applied 3-year research program is set to change the way we approach drug discovery, offering fellows a unique chance to train in data science and AI for biomedical research. As a talented fellow, you will learn to apply your computational skills to make a difference for patients and reimagine medicine at Novartis. Drug hunting is a team sport, and you will gain experience in DS&AI for drug discovery as part of a multi-disciplinary team in Biomedical Research. You will drive innovation by deploying cutting-edge data approaches in collaboration with a vibrant and diverse community of over 300 data scientists globally. The program provides a unique platform to work on real-world, biomedical data at scale, rarely accessible in academia. Under the guidance of experienced mentors, you’ll embark on a journey of professional growth, benefiting from a tailored training program with built-in time for a mini-sabbatical in other areas of Novartis and for attending conferences/workshops. Biomedical Research is the home of a vibrant postdoctoral community connected through science and events supporting the professional growth of our fellows, including monthly seminars and an annual Research Day Symposium. Seize this chance to be at the forefront of Data science and AI and shape the future of drug discovery! As a key member of an interdisciplinary team with expertise in computational and data science, AI/ML methodology, protein science, high throughput screening as well as modeling/computer-aided drug design, you will leverage state-of-the-art AI methodology and unique internal datasets to model protein-protein and protein-ligand interactions and drive drug discovery efforts. Start date: Autumn 2024 About the Role Key responsibilities As a Data Science Innovation Fellow, you will: Leverage large, proprietary data sets to fine-tune innovative AI models for protein-ligand structure predictions. Design and conduct in silico experiments to inform wet lab experiments and integrate generated data to optimize prediction models. Collaborate with cross-functional teams and apply the latest structural AI models to real world drug discovery projects. Explore the application of the latest structure-based AI methods to drug discovery workflows and present your findings to the scientific community at BR (Biomedical Research) Role requirements : PhD in computational biology, cheminformatics, structural biology or equivalent, with extensive computational experience (PhD students in the last year of their thesis work, are eligible to apply). Experience in applying computational methods to protein modeling, drug discovery or small molecule design. Strong background in structural AI methods (e.g., Alphafold, Rosetta Fold, Openfold). Proficiency in Python and machine learning libraries (e.g., TensorFlow, PyTorch, Jax) in high performance computing/cloud computing environments (e.g. AWS). Experience with protein-ligand interaction prediction and drug discovery workflows. Strong publication record or other scientific achievements (i.e. awards, patents, grants). Excellent analytical, communication, presentation and organizational skills. Passion for research and boundless curiosity. #DSIF How to apply Please submit your CV and cover letter by July 29 for consideration. Please make sure to discuss in the cover letter how this training program will help you fulfill your career goals. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No Apply to Job(link is external)
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26.07.2024

Novartis AG

Postdoc / Postgraduate Manufacturing Unit Galenic (m/w/d)

  • Novartis AG

  • Stein

  • 26.07.2024

  • Festanstellung 100%

Festanstellung 100%

Stein

Job ID REQ-10008481 Jul 22, 2024 Switzerland Summary Für die Manufacturing Unit Galenic suchen wir ab sofort eine:n motivierte:n und engagierte:n Postdoc / Postgraduate für 24 Monate, der/die einen Einblick in die Rolle des Prozessexperten/-in in der sterilen Produktion erhalten und uns aktiv unterstützen möchte. About the Role 80 Millionen! Das ist die Anzahl der sterilen Produkte, die in unserem Arbeitsplatz pro Jahr verarbeitet werden. Als Teil des Teams für die Produktion spielen Sie eine Schlüsselrolle bei der Herstellung und Sicherstellung der höchsten Produktqualität für Millionen von Patienten in mehr als 150 Ländern auf der ganzen Welt. Für die Line 2 in der Manufacturing Unit Galenic suchen wir ab sofort eine:n motivierte:n und engagierte:n Postdoc / Postgraduate für 24 Monate , der/die einen Einblick in die Rolle des Prozessexperten/-in in der sterilen Produktion erhalten und uns aktiv unterstützen möchte. Präferiertes Startdatum: sobald wie möglich, z.B. Oktober 2024; flexibel Aufgaben Unterstützung bei Untersuchung und Bearbeitung von Herstellabweichungen (Deviations) und dem CAPA-Management Identifikation von Prozessschwachstellen und Mithilfe bei Projekten zur Prozessverbesserung Erstellung und Update von SOPs Update von Herstellungsdokumenten Mithilfe bei der Dokumentationsvorbereitung und Bearbeitung von Risikoanalyse und Änderungsanträgen Erstellung von Dokumentationen und Testberichten Unterstützung bei der Mitarbeiterqualifizierung Koordination/Leitung ausgewählter Projekte Nutzung digitaler Tools und Lösungen zur Prozessverbesserung Anforderungen Abgeschlossenes Naturwissenschaftliches oder Pharmazeutisches Studium - mind. Master oder PhD (abgeschlossen innerhalb der letzten ca. 12 Monate) Gute Englisch- und Deutschkenntnisse (fliessend) Teamfähigkeit und Flexibilität Offene Kommunikation und Engagement Kenntnisse in digitalen Tools und Lösungen Programmierfähigkeiten (z.B. Python) sind von Vorteil Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Barrierefreiheit und Unterstützung: Wenn Sie aufgrund einer Erkrankung oder Behinderung spezielle Unterstützung während des Rekrutierungsprozesses brauchen und/oder deswegen detailliertere Informationen über die wesentlichen Funktionen einer Stelle benötigen, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihres Anliegens und Ihre Kontaktinformationen mit. Bitte vergessen Sie nicht, dabei die Referenznummer der Stellenausschreibung anzugeben. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Innovative Medicines Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No
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24.07.2024

Novartis AG

Postdoc / Postgraduate Manufacturing Unit Galenic (m/w/d)

  • Novartis AG

  • Stein

  • 24.07.2024

  • Festanstellung 100%

Festanstellung 100%

Stein

Job ID REQ-10008481 Jul 22, 2024 Switzerland Summary Für die Manufacturing Unit Galenic suchen wir ab sofort eine:n motivierte:n und engagierte:n Postdoc / Postgraduate für 24 Monate, der/die einen Einblick in die Rolle des Prozessexperten/-in in der sterilen Produktion erhalten und uns aktiv unterstützen möchte. About the Role 80 Millionen! Das ist die Anzahl der sterilen Produkte, die in unserem Arbeitsplatz pro Jahr verarbeitet werden. Als Teil des Teams für die Produktion spielen Sie eine Schlüsselrolle bei der Herstellung und Sicherstellung der höchsten Produktqualität für Millionen von Patienten in mehr als 150 Ländern auf der ganzen Welt. Für die Line 2 in der Manufacturing Unit Galenic suchen wir ab sofort eine:n motivierte:n und engagierte:n Postdoc / Postgraduate für 24 Monate , der/die einen Einblick in die Rolle des Prozessexperten/-in in der sterilen Produktion erhalten und uns aktiv unterstützen möchte. Präferiertes Startdatum: sobald wie möglich, z.B. Oktober 2024; flexibel Aufgaben Unterstützung bei Untersuchung und Bearbeitung von Herstellabweichungen (Deviations) und dem CAPA-Management Identifikation von Prozessschwachstellen und Mithilfe bei Projekten zur Prozessverbesserung Erstellung und Update von SOPs Update von Herstellungsdokumenten Mithilfe bei der Dokumentationsvorbereitung und Bearbeitung von Risikoanalyse und Änderungsanträgen Erstellung von Dokumentationen und Testberichten Unterstützung bei der Mitarbeiterqualifizierung Koordination/Leitung ausgewählter Projekte Nutzung digitaler Tools und Lösungen zur Prozessverbesserung Anforderungen Abgeschlossenes Naturwissenschaftliches oder Pharmazeutisches Studium – mind. Master oder PhD (abgeschlossen innerhalb der letzten ca. 12 Monate) Gute Englisch- und Deutschkenntnisse (fliessend) Teamfähigkeit und Flexibilität Offene Kommunikation und Engagement Kenntnisse in digitalen Tools und Lösungen Programmierfähigkeiten (z.B. Python) sind von Vorteil Warum Novartis? Unser Vorsatz ist es, die Medizin neu zu gestalten, um Menschenleben zu verbessern und zu verlängern. Unsere Vision ist es, das wertvollste und vertrauenswürdigste Pharmaunternehmen der Welt zu werden. Wie wir das erreichen werden? Mit unseren Mitarbeitern. Es sind unsere Mitarbeiter, die uns tagtäglich dazu antreiben, unsere Ziele zu erreichen. Werden Sie Teil dieser Mission und dieses großartigen Teams! Erfahren Sie hier mehr: https://www.novartis.com/about/strategy/people-and-culture Barrierefreiheit und Unterstützung: Wenn Sie aufgrund einer Erkrankung oder Behinderung spezielle Unterstützung während des Rekrutierungsprozesses brauchen und/oder deswegen detailliertere Informationen über die wesentlichen Funktionen einer Stelle benötigen, senden Sie bitte eine E-Mail an diversity.inclusion_ch@novartis.com und teilen Sie uns die Art Ihres Anliegens und Ihre Kontaktinformationen mit. Bitte vergessen Sie nicht, dabei die Referenznummer der Stellenausschreibung anzugeben. Treten Sie unserem Novartis Netzwerk bei: Wenn diese Position nicht zu Ihrer Erfahrung oder Ihren Karrierezielen passt, Sie aber dennoch mit uns in Kontakt bleiben möchten, um mehr über Novartis und unsere Karrieremöglichkeiten zu erfahren, dann treten Sie hier dem Novartis Netzwerk bei: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Innovative Medicines Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Job Type Full time Employment Type Praktikant*in/Student*in (Befristet) Shift Work No Apply to Job(link is external)
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19.07.2024

Novartis AG

QC Analyst I (Temporary) 2 years contract

  • Novartis AG

  • Stein

  • 19.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390991BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient’s T-cells, before returning them with the potential to save a patient’s life. This is a unique and novel personalized treatment where we work with the patient’s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities: Your responsibilities include, but are not limited to: • Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary • Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing • Work on shifts covering daytime / evening and one or both weekend days • Knowledge of LabWare LIMS and/or other QC data systems • Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements • Sample storage and management • Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes Apply to Job(link is external)Access Job Account(link is external)
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16.07.2024

Novartis AG

QC Analyst I (Temporary) 2 years contract

  • Novartis AG

  • Stein

  • 16.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390991BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient-s T-cells, before returning them with the potential to save a patient-s life. This is a unique and novel personalized treatment where we work with the patient-s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities:- Your responsibilities include, but are not limited to: Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing Work on shifts covering daytime / evening and one or both weekend days Knowledge of LabWare LIMS and/or other QC data systems Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements Sample storage and management Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes
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Merken

16.07.2024

Novartis AG

QC Analyst I (Temporary) 1 year contract

  • Novartis AG

  • Stein

  • 16.07.2024

  • Temporär (befristet) 100%

Temporär (befristet) 100%

Stein

Job ID 390993BR Jun 30, 2024 Switzerland About the Role 10 ! days - that is how long we in Cell & Gene Therapy treat a patient-s T-cells, before returning them with the potential to save a patient-s life. This is a unique and novel personalized treatment where we work with the patient-s own cells during our production process. Not only are re-imagining medicine but we are also impacting on, saving and improving quality of life. This role will help get our Cell & Gene Therapy product to reach our patient worldwide. Cell & Gene Therapy at Novartis is a very dynamic and innovative environment, focus on delivering bring therapy to the patient. Your key responsibilities:- Your responsibilities include, but are not limited to: Perform Bio-Analytical testing such as Flow, ELISA, cell count, cell viability, residual bead assessment, qPCR, Potency, in collaboration with experienced team members, if necessary Perform all testing and activities compliantly following appropriate SOPs and procedures and maintain controls, reagents and reference standards to support testing Work on shifts covering daytime / evening and one or both weekend days Knowledge of LabWare LIMS and/or other QC data systems Ensure all activities in compliance with cGxP, incl. data integrity Diversity & Inclusion / EEO We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Role Requirements Sample storage and management Knowledge of LabWare LIMS and/or other QC data systems Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit QUALITY Location Switzerland Site Stein (Säckingen) Company / Legal Entity Novartis Pharma AG Functional Area Quality Job Type Full Time Employment Type Temporary Shift Work Yes
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Merken

16.07.2024

Novartis AG

Equipment Operator

  • Novartis AG

  • Stein

  • 16.07.2024

  • Festanstellung 100%

Festanstellung 100%

Stein

Job ID REQ-10008960 May 28, 2024 Switzerland Summary -Gerätebediener -Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten nach Produktionsplan, um die rechtzeitige Produktion des Produkts mit der Qualität und Quantität in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. -Service-Operator -Ausführen zugewiesener Fertigungsaufgaben und -tätigkeiten gemäß Produktionsplan in Übereinstimmung mit den einschlägigen GMP-, Sicherheits- und Umweltrichtlinien. Führen Sie routinemäßige operative Support-Aktivitäten nach dem Herstellungsprozess und Zeitplan durch und ermöglichen Sie die zeitnahe Produktion des Produkts mit der Qualität und Quantität -Dokumentationsspezialist Admin Der Dokumentationsspezialist Admin verwaltet die Änderung, Bearbeitung, Verteilung, Überprüfung und Archivierung von GMP-Fertigungsdokumenten und die Ausgabe der Batch-Datensätze, um sie in der Qualität und innerhalb der Fristen an die Produktion zu liefern. Der Dokumentationsspezialist Admin stellt eine Reihe von Verwaltungsaufgaben sicher, die für das ordnungsgemäße Funktionieren des Geräts erforderlich sind. About the Role Major accountabilities: Participation to the manufacturing processes Execution of all assigned activities according to production schedule and in compliance with the valid GMP, work, operating, environmental and safety instructions and guidelines Minimum Requirements: Transportation experience General HSE Knowledge Knowledge of GMP Art Curator Transportation Classification (i.e. IATA or DOT) expertise Manufacturing Process Execution English language You-ll receive: Breakdown of benefits received in this role. Include flexible working, learning and development opportunities as well. Why-Novartis? 766 million lives were touched by Novartis medicines in 2021, and while we-re proud of this, we know there is so much more we could do to help improve and extend people-s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis! Commitment to Diversity & Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve. Accessibility and accommodation Novartis group is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.- Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/en\_US/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Division Operations Business Unit Pharmaceuticals Location Switzerland Site Stein Aargau Company / Legal Entity C046 (FCRS = CH028) Novartis Pharma Stein AG Functional Area Technical Operations Job Type Full time Employment Type Befristet (Befristet) Shift Work No
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