Novartis AG

Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: We are looking for experience in the field of the industrialization of Radioisotope production and related technologies, with an emphasis on isotope separation technologies and isotope development supporting our growing portfolio. Our Unit is driving successful execution of a wide range of isotope-related projects. This starts with early strategic and operational discussions on isotope production technologies, assembly of internal teams and execution of desired strategy, up to technical leadership of early process development and the developability assessment of chosen isotope separation technologies. You will be reporting to the Head of the Global Isotope Development Unit. You will be leading an Isotope Project Team consisting of Isotope Project Leads from different scientific areas who act as members of the development project teams by optimally setting up people, assets, and equipment to best serve project needs according to priority and ensure timely delivery of high-quality products and solutions. About the Role Major accountabilities: Work collaboratively with cross-functional and multidisciplinary teams, spanning multiple NVS global sites to discover and develop efficient RLTs. Build and lead internal Project management team of experimental scientists and project leads. Seek technical and operational input from key stakeholders to build the project execution plan. Lead internal project meetings. Collect and interprets data to advance project, adapts strategy, and addresses the right scientific questions. Ensure team discussions and decisions are summarized in minutes. Ensure that key milestones and go / no go criteria are data driven and clearly defined. Own quality of project information and make sure project information is accurate and included in the system(s) in a timely matter. Guide projects with respect to isotope approaches and technologies and leads corresponding efforts. Lead developability assessment, manufacturing line development and early process development. Track and oversee projects by maintaining an overview of the project goals, activities and commitments, and timelines of project teams, in line with strategic priorities. Manage and optimize project plans and resource assignments with the aim to manage/mitigate risks. Align with RLT LT project strategy and resourcing. Regular project/portfolio updates to IDU LT. Contribute to vendor/CRO evaluations, coordination of outsourcing requests, budget monitoring and communication, evaluation of external collaborations and due diligence. Plan R&D programs and recommends technological application programs to accomplish long-range objectives. Supports scientific decision making by providing advice and recommendations to global project teams. Develop concepts and propose approach, to address identified medical device/science/technology needs. Supply technical advice and counsel to other professionals and represent the organization in outside discussions and technical forums. Originate and apply complex concepts and propose new and unique approaches, methods, procedures and designs with regular use of creativity and originality to research and/or development. Assure continuity of products and processes assessment feasibility, research, design, development, compliance to customer and non-customer requirements, transfer to production. Focus on implementing and executing in own area of expertise provides thought leadership in own area. Provides leadership direction, determining and developing approach to solutions by coordinating multiple resources to solve complex problems. Minimum Requirements: PhD with a strong background in Radiochemistry and radio-isotope production technologies desired 5+ years of relevant radio/pharma experience, including industrialization of radio-isotopes Previous track record of success in leadership position, working with international and multidisciplinary development teams. Ambitious, yet highly collaborative and fully committed to team’s and project success. Result- and quality oriented. Able to deal with conflicting interests and willing to make compromises to ensure project progress. Excellent project management skills, organizational and team management skills, interpersonal communication, strong verbal and written communication. Creativity with demonstrated critical thinking and problem-solving skills, ability to pay attention to detail but also see a bigger picture. Comfortable with ambiguity and change, eager and fast learner willing to adopt new tools and processes. Ability to operate in a fast-paced dynamic environment and effectively process multiple avenues of communication and requests in parallel Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060714 Sep 01, 2025 Switzerland Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: We are looking for experience in the field of the industrialization of Radioisotope production and related technologies, with an emphasis on isotope separation technologies and isotope development supporting our growing portfolio. Our Unit is driving successful execution of a wide range of isotope-related projects. This starts with early strategic and operational discussions on isotope production technologies, assembly of internal teams and execution of desired strategy, up to technical leadership of early process development and the developability assessment of chosen isotope separation technologies. You will be reporting to the Head of the Global Isotope Development Unit. You will be leading an Isotope Project Team consisting of Isotope Project Leads from different scientific areas who act as members of the development project teams by optimally setting up people, assets, and equipment to best serve project needs according to priority and ensure timely delivery of high-quality products and solutions. About the Role Major accountabilities: Work collaboratively with cross-functional and multidisciplinary teams, spanning multiple NVS global sites to discover and develop efficient RLTs. Build and lead internal Project management team of experimental scientists and project leads. Seek technical and operational input from key stakeholders to build the project execution plan. Lead internal project meetings. Collect and interprets data to advance project, adapts strategy, and addresses the right scientific questions. Ensure team discussions and decisions are summarized in minutes. Ensure that key milestones and go / no go criteria are data driven and clearly defined. Own quality of project information and make sure project information is accurate and included in the system(s) in a timely matter. Guide projects with respect to isotope approaches and technologies and leads corresponding efforts. Lead developability assessment, manufacturing line development and early process development. Track and oversee projects by maintaining an overview of the project goals, activities and commitments, and timelines of project teams, in line with strategic priorities. Manage and optimize project plans and resource assignments with the aim to manage/mitigate risks. Align with RLT LT project strategy and resourcing. Regular project/portfolio updates to IDU LT. Contribute to vendor/CRO evaluations, coordination of outsourcing requests, budget monitoring and communication, evaluation of external collaborations and due diligence. Plan R&D programs and recommends technological application programs to accomplish long-range objectives. Supports scientific decision making by providing advice and recommendations to global project teams. Develop concepts and propose approach, to address identified medical device/science/technology needs. Supply technical advice and counsel to other professionals and represent the organization in outside discussions and technical forums. Originate and apply complex concepts and propose new and unique approaches, methods, procedures and designs with regular use of creativity and originality to research and/or development. Assure continuity of products and processes assessment feasibility, research, design, development, compliance to customer and non-customer requirements, transfer to production. Focus on implementing and executing in own area of expertise provides thought leadership in own area. Provides leadership direction, determining and developing approach to solutions by coordinating multiple resources to solve complex problems. Minimum Requirements: PhD with a strong background in Radiochemistry and radio-isotope production technologies desired 5+ years of relevant radio/pharma experience, including industrialization of radio-isotopes Previous track record of success in leadership position, working with international and multidisciplinary development teams. Ambitious, yet highly collaborative and fully committed to team-s and project success. Result- and quality oriented. Able to deal with conflicting interests and willing to make compromises to ensure project progress. Excellent project management skills, organizational and team management skills, interpersonal communication, strong verbal and written communication. Creativity with demonstrated critical thinking and problem-solving skills, ability to pay attention to detail but also see a bigger picture. Comfortable with ambiguity and change, eager and fast learner willing to adopt new tools and processes. Ability to operate in a fast-paced dynamic environment and effectively process multiple avenues of communication and requests in parallel Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Alternative Location 1 Ivrea, Italy Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The purpose of the role is to provide nonclinical regulatory toxicology expertise on R&D project teams supporting the successful initiation of clinical trials and achievement of registration for drug candidates of various modalities. The Director level Project Team Member leads cross functional associates (i.e. PCS Target Team) to develop and implement integrated nonclinical toxicology study plans, drafts regulatory responses and all required submission documentation and manages the respective project communication strategy within PCS and Novartis About the Role This hybrid role can be based in Basel or London (White City) Key Responsibilities: Leads PCS Target Teams to design, integrate and interpret results of nonclinical safety assessment program including impact to drug development and/or project timeline Represents PCS on cross functional R&D project teams to design appropriately compliant and scientifically relevant nonclinical safety package Recognize the need for a “fit for purpose and modality” nonclinical program as needed and collaborate with line functions outside of PCS to accomplish this goal Participates in internal Novartis initiatives to improve use of nonclinical/translational safety data for drug development decisions. Manages communications and builds relationships between PCS and R&D project teams Negotiates with Global Health Authorities (HA) worldwide regarding safety issues, scientific interpretation and acceptability nonclinical safety package to support clinical trials and market approval. Responsible for authoring nonclinical safety sections of internal and regulatory documents supporting clinical development and market approval May evaluate in/out-licensing opportunities and carries out technical Due Diligence activities upon request. Participates or Leads internal and/or external cross-functional groups on key initiatives focused on PCS objectives and/or current nonclinical safety topics. Mentors colleagues on drug development strategy and project-related matters Essential Requirements: Minimum of 5 years experience as a nonclinical safety Project Team member; Demonstrated experience in the preclinical development of small molecule, biotherapeutics and/or gene and cell therapies and the safety issue awareness of these modalities. 8+ years experience in a nonclinical drug development scientific discipline (e.g. study director, project team toxicologist or pharmacologist). Demonstrated experience in direct or written communication of strategy and data to global health authorities, supporting clinical development and market approval. Knowledge of drug development strategy for immunomodulatory drugs Leadership in cross-industry organizations (discipline-related or related to drug development). Excellent interpersonal, leadership, organizational skills (e.g. planning and time management) and teamwork skills. Excellent oral and written communication and influencing skills. Highly efficient, self-motivated, flexible and able to work independently and efficiently under time constraints. Ability to focus and work on several projects simultaneously and to effectively manage conflicting expectations from the line unit, TA Strategy team and project teams in a matrix management environment. Customer focused thinking. Recognized ability to represent PCS on Novartis cross functional decision boards or other cross functional project teams. Recognized expertise in technical and scientific problem solving in a project driven, multi-disciplinary international environment. Ability to mentor and coach Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) #LI-hybrid Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland OR Ivrea, Italy Role Purpose: Act as Isotope Project Lead (IPL) by providing the specialist knowledge and expertise as Subject Matter Expert (SME) of radioisotope production and purification with particular focus on assessing, developing, and optimizing new technologies that support RLT products Life Cycle Management (LCM). Develop, optimize and transfer radioisotopes production and purification/separation processes. This is done in close collaboration with the relevant development centers, and Contract Manufacturing Organizations (CMOs). About the Role Major accountabilities: Manage inter functional project plan and budget using the Project Planning tool or System Identify issues and potential bottlenecks within projects and proposes options Contribute to the Radioisotope TRD-related activities. Ensure constant technological survey on the field of radioisotopes production. Apply scientific/technical expertise to identify new programs of interest for the company and support their development from early evaluation up late phase supply. Participate to development programs and activities around isotopes in adherence with global Isotope strategy and objectives within agreed timelines and budget, timely report key advancements and challenges. Identify strategic external partners for the activation of research collaboration agreement to develop new production technologies/ access to innovative isotopes. Implements strategic policies when selecting methods, techniques, and evaluation criteria for obtaining results. Establishes and assures adherence to budgets, schedules, work plans, and performance requirements. Represents area as core member in the Global Project Teams for defining global scientific strategy for development up to submission and approval in major markets of assigned product(s). Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable) Minimum Requirements: BSc. in Chemical Engineering, Pharmaceutical Technology, or equivalent scientific degree. Desirable MSc., PhD or equivalent experience. Desirable degree in Radiochemistry and strong scientific knowledge in nuclear medicine Successfully demonstrated several years (minimum of 5 years) of directly related experience in a scientific area or Ph.D. or equivalent Proven Project Leadership in all project phases Proven process understanding (Pharma, GMP, Validation and Regulatory aspects). Sound experience of data handling and applied statistics is a must. Strong understanding of risk assessment and risk management fundamentals/tools Quality-oriented with attention to detail Excellent verbal and written communication skills Excellent problem solving and decision-making skills Defining and implementing productivity improvement measures. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis Pharma AG is seeking a Legal Brand Protection Paralegal to join the IP and Legal Support function. This is a terrific opportunity to work independently and take ownership of the trademark, copyright and domain name portfolio, supporting an important, fast paced and dynamic business. Work alongside a high performing team of professionals on operational improvement initiatives. The position offers the opportunity to interact directly with business clients and trademark counsels worldwide. You will work and collaborate closely with the Legal Brand Protection Attorneys and Legal Brand Rights Creation group, collaborate on complex substantive and operational excellence projects across the larger IP organization based in many countries around the world. Discover our curious and unbossed culture! We are not able to offer relocation for this position and will only consider candidates able to be in the Basel office on a hybrid working model. About the Role Key responsibilities: Proactively manage all operational tasks related to the trademark (TM) portfolio, ensuring continuity and timely handling of deadlines and correspondence. Independently draft responses to domestic and international trademark agents with minimal attorney input. Provide guidance and oversight on draft responses prepared by other paralegals within the Legal Brand Production (LBP) team. Support attorneys on complex trademark matters and ensure consistent operational backup. Identify, analyze, and resolve data inconsistencies in TM records, reporting findings and improvements to stakeholders. Maintain and enhance TM operational procedures, especially during supervisor absences, and lead process improvement initiatives. Coordinate attorney trademark work with internal filing teams and external service providers, ensuring data accuracy and file completeness. Mentor and onboard new LBP attorneys and paralegals, providing comprehensive briefings on IP Services and LBP support functions. Contribute to training development, lead workshops, and support role evolution within the LBP and IP Services teams. Act as deputy in the absence of managers or colleagues, managing meetings, workload distribution, and team coordination. Contribute to exploring and implementing AI opportunities in LBP to drive efficiencies Essential Requirements: Several years of paralegal experience in a law firm or corporate in-house setting; paralegal certificate and college degree preferred. Strong organizational, analytical, and communication skills with a high attention to detail and problem-solving mindset. Proven ability to manage large, multi-national trademark portfolios, including U.S., EU, WIPO (Madrid System), and international filings. Skilled in trademark portfolio management tasks such as online searches, analyzing search reports, and preparing filing materials. Experience supporting attorneys with trademark use identification on packaging and promotional materials. Capable of managing high workloads, prioritizing tasks, and delivering results in a fast-paced environment. Familiarity with drafting and reviewing license, prior-rights, and consent agreements. Effective team player with strong interpersonal skills and willingness to mentor and collaborate across functions. Proficient in trademark docketing systems, electronic file management, and domain name portfolio/UDRP actions. Knowledge of copyright law and the pharmaceutical industry is a plus. Commitment to Diversity and Inclusion / EEO paragraph Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and Accommodation: Switzerland: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10053839 Sep 10, 2025 Switzerland Summary Novartis Pharma AG is seeking a Legal Brand Protection Paralegal to join the IP and Legal Support function. This is a terrific opportunity to work independently and take ownership of the trademark, copyright and domain name portfolio, supporting an important, fast paced and dynamic business. Work alongside a high performing team of professionals on operational improvement initiatives. The position offers the opportunity to interact directly with business clients and trademark counsels worldwide. You will work and collaborate closely with the Legal Brand Protection Attorneys and Legal Brand Rights Creation group, collaborate on complex substantive and operational excellence projects across the larger IP organization based in many countries around the world. Discover our curious and unbossed culture! We are not able to offer relocation for this position and will only consider candidates able to be in the Basel office on a hybrid working model. About the Role Key responsibilities: Proactively manage all operational tasks related to the trademark (TM) portfolio, ensuring continuity and timely handling of deadlines and correspondence. Independently draft responses to domestic and international trademark agents with minimal attorney input. Provide guidance and oversight on draft responses prepared by other paralegals within the Legal Brand Production (LBP) team. Support attorneys on complex trademark matters and ensure consistent operational backup. Identify, analyze, and resolve data inconsistencies in TM records, reporting findings and improvements to stakeholders. Maintain and enhance TM operational procedures, especially during supervisor absences, and lead process improvement initiatives. Coordinate attorney trademark work with internal filing teams and external service providers, ensuring data accuracy and file completeness. Mentor and onboard new LBP attorneys and paralegals, providing comprehensive briefings on IP Services and LBP support functions. Contribute to training development, lead workshops, and support role evolution within the LBP and IP Services teams. Act as deputy in the absence of managers or colleagues, managing meetings, workload distribution, and team coordination. Contribute to exploring and implementing AI opportunities in LBP to drive efficiencies Essential Requirements: Several years of paralegal experience in a law firm or corporate in-house setting; paralegal certificate and college degree preferred. Strong organizational, analytical, and communication skills with a high attention to detail and problem-solving mindset. Proven ability to manage large, multi-national trademark portfolios, including U.S., EU, WIPO (Madrid System), and international filings. Skilled in trademark portfolio management tasks such as online searches, analyzing search reports, and preparing filing materials. Experience supporting attorneys with trademark use identification on packaging and promotional materials. Capable of managing high workloads, prioritizing tasks, and delivering results in a fast-paced environment. Familiarity with drafting and reviewing license, prior-rights, and consent agreements. Effective team player with strong interpersonal skills and willingness to mentor and collaborate across functions. Proficient in trademark docketing systems, electronic file management, and domain name portfolio/UDRP actions. Knowledge of copyright law and the pharmaceutical industry is a plus. Commitment to Diversity and Inclusion / EEO paragraph Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and Accommodation: Switzerland: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We’re a dedicated team united by a drive to deliver significant value to Novartis. As an individual contributor you will participate in internal audits as part of an audit team working under the guidance of the audit team leader. You will perform functional audits that assess risks within Research, Development and Strategy & Growth and evaluate related internal controls in accordance with Novartis IA’s methodology standards. About the Role Key Responsibilities: Conduct audits in areas that have established control frameworks in close co-operation with the team leader. Build effective business partnering relationships with senior management on the audit or advisory engagement and with managers in the relevant functions, while maintaining the independence and objectivity of self, the audit team and the Internal Audit function. Support the audit team in the annual assessment of operational risks across the region. Support team leaders in the planning of audits. Identify and evaluate risks and controls across the range of Novartis businesses and functional areas. Support the team leader in delivering audit reports, including reviewing and agreeing issues with responsible management. Build effective relationships with staff and management on the audit in order to obtain information, discuss and agree solutions to control issues and to communicate findings. Perform special projects and other duties and provide input on audit practices, tools and administrative activities. Keep up to date with the audit methodology and the use of technology. Essential Criteria: Good Experience as Internal Auditor. Fluent in English: oral and writing Desirable criteria Life science industry experience ideally in Pharma. Certified Internal Auditor (CIA) Must have the ability to travel domestically/internationally (Max 20% travel) Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you eager to dive into the world of People & Organization, combining your passion for people development with impactful projects that shape workplace culture and efficiency? Join us as a P&O Intern and bring your skills to life! We are looking for an agile, creative and collaborative profile to join our Development P&O team. About the Role Preferred start date / asap? : As soon as possible Latest start date / flexible? : November 15, 2025 – December 1st, 2025 Duration: 12 months Major accountabilities: P&O data analytics -Supports with Functional P&O analytics and KPIs reporting- Analysis and interpretation of P&O relevant data/trends. Provide data and process support, coordination, and consolidation of information in Global, Region, and Countries to streamline P&O service delivery model in partnership with Various P&O , finance and other stakeholders. Project Management support in areas of Talent Management, Organization, Culture , Operational Excellence and other organizational initiatives. Participate in key P&O projects and provide related support - Project participation, coordination and management including scheduling, tracking, follow up on minutes. Supports team in setting up relevant meeting, communication channels etc. Minimum Requirements: Finished bachelor’s degree and / or nearly finished master’s degree in human resources, Organizational Psychology or Business Administration (graduation not longer than 12 months ago) Skills: Analytical and problem-solving skills. Strong skills in tools of MS Word, Excel skills and MS PowerPoint. Knowledge of other analytical tools is a plus. Agility to work in a cross-functional international environment. Strong verbal and written communication and interpersonal skills Client-focused action-oriented approach to work and ability to build collaborative relationships. Ability to work independently and demonstrate initiative. Languages : Fluent in both written and spoken English. Additional language, if used for local Business purposes. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 7 years of experience in clinical research or drug development (Senior 10 + years plus) Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland Are you a seasoned IP leader ready to shape the future of pharmaceutical innovation at a global scale? At Novartis, we’re seeking a Global Head of IP Transactions to lead high-energy and high-impact patent and IP diligence across more than 100 M&A and BD&L deals annually. This is a unique opportunity to influence strategic decisions, collaborate with top-tier legal and business teams, and drive IP excellence for the most transformative medicines in the world. Join us in a role where your expertise will directly support breakthrough therapies and deliver lasting value to patients and society. About the Role Key Responsibilities: Coordinates, manages, leads, and drives the IP diligence and strategy for transactions (M&A and BD&L), using the support of all enterprise, legal, and IP functions in the analysis of IP issues (patents, trademarks, trade secrets), resulting in proactive, timely, thorough, and comprehensive advice on all relevant issues. Ensures clear, well-communicated, and accurate IP advice for all M&A and BD&L deals, recognizing the time-sensitive nature of transactions requires constant attention also during non-standard working hours. Develops and drives the IP and regulatory transaction governance framework, establishes appropriate tools and processes, and leads high-visibility, complex global IP transactions projects. Advises the Global Head IP and the Global Head Legal Transactions, as well as other senior business leaders, on IP transactions and risk exposure, including strategies for minimizing adverse consequences. Builds strong interface with M&A/BD&L colleagues to ensure transactions are supported by IP staff trained and equipped to advise on all IP aspects of transactions and manages external counsel providing diligence information and contract clauses. Ensures exchange of information and know-how across the enterprise and provides training, with the goal that in-house and external lawyers take a consistent and proactive approach in effectively dealing with IP transactions, and that stakeholders are advised early and proactively of IP issues impacting the deal business cases. Leads the IP Transactions team, ensuring that their services are timely, proactive, targeted, and of high quality. Retains and develops key talents within IP, particularly in IP transactions. Member of IP Leadership Team (IPLT) and Transactions Legal Leadership Team (TLLT) Essential Requirements: Law school graduate (Common or Civil Law) with an additional science degree, Common Law and admission to the bar preferred; Patent attorney qualification required Extensive, multi-year IP transactions and diligence experience within a pharmaceutical company or with health care clients, including experience leading a team Sound knowledge of related following disciplines: Regulatory, Antitrust, and Contracts paired with a good understanding of Corporate, Tax Proven ability to deal positively when working under time pressure and with demanding clients as well as in handling a high volume of activity involving multiple, often complex projects simultaneously Proficiency in English (written and spoken), other languages are a plus Benefits and Rewards: Company Pension Plan, Life and Accidental Insurance, Meals Allowance or Canteen in the office, Flexible working hours. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity and Inclusion Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Director (CDD) in the Cardio Renal & Metabolic (CRM) Development Unit is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As a CDD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive the execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: • Providing clinical leadership and strategic input for all clinical deliverables in the assigned project or section of a clinical program. Clinical deliverables may include clinical sections of individual protocols or sub studies consistent with the Integrated Development Plans (IDP), clinical data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications • Leading development of clinical sections of trial and program level regulatory documents • Driving execution of the section of the clinical program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, if applicable • Overseeing/conducting ongoing medical and scientific review of clinical trial data with Clinical Scientific Expert(s) with appropriate oversight from Medical Lead • Supporting (Sr.) GPCH in ensuring overall safety of the molecule for the assigned section and may be a core member of the Safety Management Team, supporting overall program safety reporting in collaboration with Patient Safety • As a clinical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards • Contributing to scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise medical/scientific training and may be the Program Manager of other associates Minimum Requirements: • Advanced degree in life sciences / healthcare (or clinically relevant degree) is required. PharmD or PhD is strongly preferred • Fluent oral and written English • Minimum 7 years experience in clinical research or drug development • Working knowledge of the assigned disease area is desired with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) or program level • Demonstrated ability to establish effective working relationship with key investigators • Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes • Strong communication skills with the ability to work in a cross functional and global organization Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people - and - culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits - rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: The Director, Global External Partner Management RLT is responsible for leading the external CMC development efforts of the Global RLT TRD platform, inclusive of both create & supply domains. In addition, the incumbent will be responsible for evolving the overall TRD RLT externalization strategy in alignment with the TRD RLT LT. Leading the RLT External Partner Management team, overseeing TRD RLT global external operations, and third-party compliance processes, are key elements of the role. The incumbent will also manage the interfaces related to third party oversight and management and will function as the TRD RLT representative to the TRD External Partner Management network and will also be a member of the TRD RLT Leadership Team. About the Role Major accountabilities: Lead the global External Partner Management (EPM) team consisting of ca. 5-10 associates based in Switzerland, US, and Italy. Work closely with the RLT LT and contribute to the RLT make versus buy strategy definition to proactively complement line function capabilities and capacities to best serve a growing portfolio. Drive the resulting outsourcing strategy on behalf of the TRD RLT LT and align category strategies cross-functionally with business representatives and global functions such as Quality, Procurement, HSE and Technical Operations. Build and maintain a strong network of CDMOs which can provide (radio-) pharmaceutical services associated with medical isotopes, DP development and manufacturing, as well as analytical support services. Establish solid business partnerships with BR/TCO, GCO/VPG and Operations/ESO to enable seamless development efforts across the RDC continuum Set Key Performance Indicators and monitor performance of external vendors, in collaboration with procurement. Lead issue resolution and prevention initiatives in line with MSAs and Quality Agreements with Service Providers Ensure that both strategic and operational objectives are met or exceeded by setting appropriate priorities and building collaborative partnerships with external vendors for capability gains Provide professional negotiation expertise with strategic (e.g., IP, technology, contract agreements) and transactional focus (vendor management) for effective collaboration with Legal, QA and Procurement. Ensure best-in-class partnership with third party vendors. Maintain ongoing oversight of the Outsourcing and offshoring activities. As the single point of accountability for RLT externalization efforts, proactively assess relevant risks and put effective measures in place to mitigate them, drive productivity, quality and ensure time deliverables and milestones. Collaborate with the Global RLT LT and interface partners (project and technology managers) to ensure accurate allocation of projects and actively support project teams in project execution at third parties. Managing the skills and competency development of the RLT EPM team, including training development and knowledge management capabilities Budget management and oversight for external spend in alignment with TRD RLT functional heads Minimum Requirements: Ph.D., MBA or related life science field Minimum of 10 years of relevant experience; minimum of 5 years in a leadership position with successful performance and track record in the role of line/people manager or matrix manager in the pharmaceutical industry, preferably in drug development or a related industrial area (e.g., TechOps; TRD) Broad knowledge in pharmaceutical development processes, quality and regulatory requirements with focus on Phase I-III / Registration / Life cycle management projects Proven track record of successfully managing interfaces to other functions within and outside TRD. A proven track record in leading multidisciplinary, multicultural groups with people having widely varying backgrounds Languages : English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This team within Discovery Sciences at Novartis Biomedical Research is at the forefront of integrating AI-powered tools into the drug discovery pipeline. Through collaboration in multidisciplinary and cross-functional teams, we are driving the adoption of these technologies to advance early-stage drug discovery, including the development of wet lab workflows informed by computational (in-silico) results— and vice versa. If you thrive on turning scientific challenges into computational solutions that enhance data-driven drug discovery, we encourage you to apply today. As part of a global Data Science group, you will engage with experts in structural bioinformatics, computational biology, cheminformatics, and imaging. This position offers a unique opportunity to apply cutting-edge structure-based AI approaches—such as protein–ligand co-folding and peptide design—to generate meaningful impact through collaborative wet and dry lab work. About the Role Role Responsibilities Apply AI technologies to drive progress in drug discovery projects with a focus on protein biology, including protein–ligand co-folding and peptide design. Collaborate with wet-lab specialists (structural biologists, biophysicists, protein chemists) to move structure-informed drug discovery forward using innovative, AI-enabled strategies. Develop and adapt structure-based computational methodologies tailored to project objectives. Integrate proprietary data from protein crystallography, biomolecular NMR, cryo-EM, biophysics, and screening into predictive AI models. Leverage internal and external protein data resources to create impact in drug discovery. Candidate Profile PhD or equivalent experience in structural biology, bioinformatics, cheminformatics, molecular modeling, or a related scientific discipline. Must have direct experience with modern computational tools for protein and peptide design, as well as co-folding applications. Solid understanding of molecular recognition and protein-ligand binding energetics. Competence with machine learning frameworks such as PyTorch or TensorFlow. Proficiency in scripting languages (Python, R) and high-performance computing environments on Linux. Experience automating workflows and scripting for large-scale data processing. Ability to work effectively in fast-paced, innovative settings focused on solution-driven approaches. Strong communication skills, able to present complex findings clearly in both spoken and written formats. Desirable Qualifications Understanding of drug discovery and structure-based drug design. Experience with advanced machine learning techniques. Familiarity with relational databases and SQL. Experience utilizing AWS resources. Background in protein and peptide design. Expertise in structural biophysics methods. Experience working at the wet-dry lab interface. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary At Novartis, we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. In 2020, we reached >800 million patients with our products. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks. In Global Discovery Chemistry (GDC) at Novartis Biomedical Research in Basel, Switzerland, we are at the core of Novartis’ purpose, designing and making new molecules for treating patients. We are looking for a highly motivated, passionate chemist with a curious mindset and cultural agility to invent innovative medicines and help advance the frontiers of drug discovery. Join us and help reimagine medicine! About the Role Your responsibilities will include but are not limited to: Plan and execute chemical syntheses of novel drug molecules (including LMW and bRo5) aided by in silico tools and facilitated by state-of-the-art synthetic methodologies and technologies (automation, miniaturization). Experiment in a first-class laboratory infrastructure and evaluate and deploy novel synthetic technologies to progress projects. Work collaboratively in a multidisciplinary project team and integrate experimental data to develop scientific hypotheses and prioritize novel molecules for synthesis to answer key project questions. Intellectual contribution to the success of project(s) e.g. design of novel compounds and synthesis routes as well as application of data analysis and digital tools. Support and coach other team members by sharing your know-how and experience. Discuss and communicate scientific results at project/group meetings. Take over responsibilities to maintain the highest levels of laboratory safety and infrastructure. Minimum Requirements What you will bring to the role: Degree from a University or Fachhochschule (BSc, MSc or Diplom) with a strong focus on synthetic organic chemistry, or education as Lab Technician / Chemielaborant (or equivalent apprenticeship) with significant further chemistry training. At least 7 years of drug discovery experience with excellent theoretical and practical knowledge in synthetic organic and medicinal chemistry. A strong passion for hands-on chemistry experimentation in the laboratory. Ability to critically interpret results, build new experimental hypotheses, take calculated risks and make smart decisions. Interest in disruptive technologies and science trends, such as data science and automation/miniaturization, and their application to drug discovery. Experience in overseeing synthesis conducted at Contract Research Organizations (CROs) is viewed as an advantage. Experience with molecules in the bRo5 chemical space such as peptides or siRNA is not a requirement but is viewed favorably. A mind-set of curiosity, creativity, collaboration and openness to diverse thinking, with an enthusiasm to develop yourself and others, along with having excellent oral and written communication skills. Aptitude to work in a fast-paced team-oriented matrix environment to collaborate within a highly dynamic team. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary BioMedical Research (BR) is the global pharmaceutical research organization of Novartis. With approximately 6,000 scientists and physicians around the world, our research is focused on discovering innovative new drugs that will change the practice of medicine. We have an open and entrepreneurial culture, encouraging collaboration to make effective therapies. At BR, our mission is to discover innovative medicines that treat disease and human health. To do that, our scientists need cutting-edge, state-of-the-art computing systems. With Research Informatics (RX), BR is making a strategic investment into informatics capabilities and is positioning itself to deliver the systems and services that are critical to the future of drug discovery. The Scientific Data and Products (SDP) group in RX builds and applies excellence in product and data management to continuously improve the impact and value of software and data to Biomedical Research. We deliver intuitive, intentional, and integrated software solutions that create a frictionless user experience. About the Role Purpose of the role: As Product Manager Drug Candidate Selection, you play a leading role in defining the future of our suite of software applications used by over 2,000 scientists in BR to search, analyze, and visualize project data to derive insights and drive high-quality decisions in our drug candidate selection process – both for classical small molecules as well as new therapeutic modalities. Key Responsibilities You combine your knowledge of informatics and chemistry/biology applied to drug discovery with your matrix leadership skills to manage and evolve a high-impact product consisting of a portfolio of chemistry and new therapeutic modalities software applications. Together with a Product Operations Manager and an Engineering Lead, you will co-lead a matrixed product team, ensuring the initiatives you lead contribute to an intentional, integrated, and capability-based product architecture and continuously increase the value to drug discovery in BR. You provide scientific expertise to the product team, sharing a deep understanding of drug discovery data including how to integrate and visualize scientific data from multiple disparate sources (e.g. chemical structures, dose response, and structure activity relationships). You collaboratively provide strategic context and focus to the teams, act as facilitator to prioritization, and cultivate good team-based decision-making practice to increase the value of the Product towards the strategic mandate of your Product Line. You actively and transparently manage, and communicate to, all key stakeholders to co-create visions and roadmaps for the initiatives you lead, and you define how we measure their success and value delivery. This includes partnering with multiple providers as well as the large community of system users, meeting frequently with key stakeholders to set the product roadmap. You shape your teams’ culture and processes for success by exemplifying excellence in leadership and product management. Role Requirements Leading effectively in a co-leadership model inside of a global matrix organization. Ability to effect change, manage conflict, and create alignment through direct and indirect influence. Creativity in identifying, encouraging, and accelerating innovative solutions. Domain expertise in core drug discovery disciplines such as chemistry and new therapeutic modalities (e.g. xRNA, RLT, complex biologics). Experience in managing complex suites of interdependent scientific applications and data sources. Experience with chemistry related data management, analysis, and visualization in a drug discovery setting. Agile mindset and experience with Agile software development. 7+ years of experience in an informatics related role in a drug discovery matrixed environment. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll Receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Join our Novartis Network : If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Expert to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time they leave the discovery laboratory until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Expert with experience in Oligonucleotide analytics. About the Role Major accountabilities: You will help leading analytical activities within a Technical CMC project team (e.g., help to define control and specification setting strategies for Drug substances and Drug products, method development, validation, stability, and release testing) You provide valuable input to the analytical CMC documents and support regulatory submissions. Manage interactions and contribute to a high level of collaboration with internal and external stakeholders. Write of analytical source documents (e.g Analytical methods, Specifications, Validation reports, Stability reports) Lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. You will be responsible to evaluate and implement new analytical methodologies with the aim of bringing the lab at the forefront of Oligonucleotide analytics. You will be responsible for writing and reviewing analytical documentations with a high focus on quality, data integrity and timelines. You will drive, lead, and manage analytical activities including impurity profiling related to the analytical development of Oligonucleotides (e. g. method development, validation, stability, and release testing). Provide scientific guidance to the cross-functional and global project teams and thereby scientifically driving our exciting Oligonucleotide portfolio. Display a collaborative and inspired attitude within the Oligonucleotide lab, project teams and stakeholders is key. What you’ll bring to the role: Desirable: PhD in analytical chemistry or equivalent and a minimum 3 years’ experience in the pharmaceutical industry in analytical development, preferably in development of sterile parenteral products. Strong expertise in the field of oligonucleotide analytics. Profound knowledge in analytical separation techniques such as liquid chromatography (RP, IEX and HILIC) is a must. Experience in method development and troubleshooting. Experience in developing control strategies. Profound expertise in Mass Spectrometry (ranging from mass confirmation to actual quantitative analysis of impurities and sequencing) is a plus. Proven leadership in guiding and mentoring colleagues GMP experience and qualification expertise in a GMP environment are assets. Strong coordination skills, collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus Eager to develop new methods and assess new analytical techniques. High level of intrinsic motivation, excellent collaborative spirit and agility are key elements for our success. Analyse and interpret complex situations, provide detailed directions for analytical approaches Languages : English. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: We are looking for an Analytical Project Leader to support Analytical Research & Development (ARD) in the area of Project management. ARD sits within the Technical R&D department of Novartis Development and plays an essential role in the characterization and analysis of Drug Substances and Drug Products from the time the compounds leave the discovery laboratories until they are transferred to Commercial Production. We are looking for a highly motivated and experienced Analytical Project Leader with experience in Oligonucleotide analytics. About the Role Your main responsibilities: You will be a member of a global CMC subteam, which is responsible for leading the technical development of Drug Substance and Drug Products from early to late phase clinical development. You will manage analytical activities within a Technical CMC project team (e. g. defining control and specification setting strategies for Drug substances and Drug products of small molecule new modalities (e.g. xRNAs) In your role, you will be leading an analytical subteam and preparing analytical project plans and be accountable to meet quality, timelines and budget for assigned projects. You are responsible to accurately forecast FTE and cost demand for your assigned projects. You are responsible for the timely issuance of analytical source documents (e.g., Specifications, Validation reports, Stability reports, etc.) You provide scientific inputs to the analytical CMC documents and support regulatory submissions. You collaborate with internal and external stakeholders of drug development and coaching of analytical experts. You lead outsourced analytical activities at CROs / CDMOs and contribute to manage the external partnership. Educational background: Desirable: PhD in analytical chemistry or equivalent and a minimum of 5 years’ experience in the pharmaceutical industry in analytical development as project leader, preferable in development for sterile parenteral products. Experience in Oligonucleotides analytic is a plus. Proven knowledge in Early or late phase parenteral development and filings Proven leadership experience in managing development projects, ideally in a global matrix environment. Excellent understanding and awareness of regulatory guidelines for analytical development. Collaborative spirit, self-driven attitude, high level of learning agility are key attitudes Strong quality focus and experience in a cGMP environment. High level and intrinsic motivation to work with new development compounds where it is sometimes necessary to go the extra mile is a key element to our success. Broad scientific knowledge in chemistry, pharmaceutical or analytical sciences, ability to perform in a highly dynamic environment. Good scientific/technical writing skills. Good understating on how to use novel digital tools to become more productive in a global project management environment. Proven leadership in guiding and coaching colleagues Excellent communication and role model skills Fluent in English (oral and writing), German/ French a plus Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are 100 quantitative scientists supporting more than 80 clinical development projects in 10 therapeutic areas every day. As the Associate Director Pharmacometrics, you will drive the pharmacometric strategy for programs in multiple indications or a disease area. You will define the quantitative strategy that will be part of the Integrated Development Plans (IDP) for projects in Research and Early Development. In this role, you will perform or supervise execution of the pharmacometrics strategy in those programs with focus on implementing model-informed drug development (MIDD) approaches. You may manage a portfolio of projects at the disease area or indication level. You will set the strategy for informed decision making at early-stage project milestones, directly influencing drug development decisions with internal and external partners. About the Role Your Key Responsibilities: Provide global strategic pharmacometrics leadership for integrated development plans of medium to high complexity, based on relevant technical and disease area knowledge Lead and drive PMX contributions to integrate relevant technical and scientific knowledge in the planning and execution of robust quantitative development programs with focus on MIDD strategies Drive and coordinate the synthesis and integration of pharmacometrics information to support transition of drug development milestones / decision boards; identify alternative strategic options to mitigate risk on clinical programs Act as the PMX representative on early project teams and contribute to interactions with Health Authorities (e.g., responsible for PMX contributions to Briefing books, Investigator brochures, etc.) Proactively interact with partner line functions (pharmacologists, clinicians, statisticians, preclinical modelers, biomarker experts) on quantitative pharmacology aspects Plan, develop, execute and document PMX analyses Contribute to Integrated Evidence generation by leveraging disease progression and PKPD modeling techniques using various data sources (e.g., literature or Real-World Data); use historical data and knowledge for early benchmarking of assets Represent PMX in due-diligence teams to evaluate in-licensing opportunities Essential Requirements: Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent) with 6+ years’ experience in clinical drug development applying model-based methods using NLME methods and its application in Dose-exposure-response analysis, population PK/PD modeling, disease progression modeling and clinical trial simulation in academia and/or industry Clinical pharmacology, statistics and therapeutic knowledge in one or more disease areas Diverse experience in pharma industry on incorporation of MIDD strategies into drug development plans across all phases and answering challenging questions on dose and regimen justification, study design, safety analysis among others Track record of contributions to external whitepapers/ policy shaping best practice in pharmacometrics. Internally and externally established track record of developing/establishing pharmacometrics excellence Scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy. Track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10057260 Jul 17, 2025 Switzerland Summary We are 100 quantitative scientists supporting more than 80 clinical development projects in 10 therapeutic areas every day. As the Associate Director Pharmacometrics, you will drive the pharmacometric strategy for programs in multiple indications or a disease area. You will define the quantitative strategy that will be part of the Integrated Development Plans (IDP) for projects in Research and Early Development. In this role, you will perform or supervise execution of the pharmacometrics strategy in those programs with focus on implementing model-informed drug development (MIDD) approaches. You may manage a portfolio of projects at the disease area or indication level. You will set the strategy for informed decision making at early-stage project milestones, directly influencing drug development decisions with internal and external partners. About the Role Your Key Responsibilities: Provide global strategic pharmacometrics leadership for integrated development plans of medium to high complexity, based on relevant technical and disease area knowledge Lead and drive PMX contributions to integrate relevant technical and scientific knowledge in the planning and execution of robust quantitative development programs with focus on MIDD strategies Drive and coordinate the synthesis and integration of pharmacometrics information to support transition of drug development milestones / decision boards; identify alternative strategic options to mitigate risk on clinical programs Act as the PMX representative on early project teams and contribute to interactions with Health Authorities (e.g., responsible for PMX contributions to Briefing books, Investigator brochures, etc.) Proactively interact with partner line functions (pharmacologists, clinicians, statisticians, preclinical modelers, biomarker experts) on quantitative pharmacology aspects Plan, develop, execute and document PMX analyses Contribute to Integrated Evidence generation by leveraging disease progression and PKPD modeling techniques using various data sources (e.g., literature or Real-World Data); use historical data and knowledge for early benchmarking of assets Represent PMX in due-diligence teams to evaluate in-licensing opportunities Essential Requirements: Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent) with 6+ years- experience in clinical drug development applying model-based methods using NLME methods and its application in Dose-exposure-response analysis, population PK/PD modeling, disease progression modeling and clinical trial simulation in academia and/or industry Clinical pharmacology, statistics and therapeutic knowledge in one or more disease areas Diverse experience in pharma industry on incorporation of MIDD strategies into drug development plans across all phases and answering challenging questions on dose and regimen justification, study design, safety analysis among others Track record of contributions to external whitepapers/ policy shaping best practice in pharmacometrics. Internally and externally established track record of developing/establishing pharmacometrics excellence Scientific leadership skills demonstrated in facilitating and optimizing the clinical development strategy. Track record for global scientific leadership in the development and evaluation of modern program/trial design methodologies Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Verantwortlich für das Arzneimittelüberwachungsprogramm einschließlich der notwendigen Nachverfolgung, Risikobewertung und Produktverwandtwerden zu Berichten über Nebenwirkungen, Aufsicht über die Sicherheit in klinischen Studien und Post-Marketing-Programmen. Beteiligt sich an der Lösung jeglicher rechtlicher Haftung und der Einhaltung behördlicher Vorschriften. Bietet und trägt zur Trend- und Sicherheitssignalerkennung und Risikomanagementbewertung für den Lebenszyklus der Produkte bei. Bietet Sicherheitsunterstützung für die klinischen Entwicklungsteams. About the Role #LI-Hybrid Location: Basel, Switzerland Working Model: Hybrid Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible. Key Responsibilities Lead scientific projects and evaluations of safety topics across early development, full development, and marketed products Guide mechanistic investigations and integrate safety insights into cross-functional development activities Co-lead Safety Science platform meetings such as the Early Safety Hub (ESH) and Early Portfolio Safety Group (EPSG) Support preparation and scientific quality of safety board meetings, including Integrated Safety Assessment Board (ISAB) and Medical Safety Review Board (MSRB) Review and advise on mechanistic studies, Risk Management Plans, and safety signal action plans Contribute to safety training and knowledge sharing within Patient Safety as well as important clinical partner functions (Clinical Development, Translational Medicine and Translational Clinical Oncology) Collaborate with internal and external experts to advance safety science standards and practices Essential Requirements Medical degree (preferred) or PhD with relevant drug safety experience in a pharmaceutical or biotech company Peer-reviewed publications in pharmacology, clinical research or safety 3–5 years of postdoctoral or clinical experience 3–5 years of drug development experience in academia or the pharmaceutical industry Proven experience preparing clinical safety assessments and regulatory safety submissions Strong leadership in cross-functional, multicultural team environments Deep understanding of clinical trial methodology, regulatory standards, and scientific writing Fluent in English, both spoken and written Desirable Skills Understanding of an additional major language (e.g. French or German) Experience contributing to external scientific collaborations in drug safety Ready to shape the future of safety? Apply now and bring your scientific leadership to a team that’s transforming lives. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Join our team at data42! The vision of data42 is to inspire collaborative groundbreaking data and AI initiatives, to reimagine drug discovery at Novartis and accelerate time to market, ultimately transforming healthcare and improving lives. We are a small team dedicated to bringing this vision to life by accelerating secondary research and data-driven decisions where we provide scientific support and data ready for analysis in a collaborative environment, leveraging a secure and governed AI-enabled platform The Semantics Technologies Associate Director will Lead data42’s implementation of Semantics and Metadata standards and be responsible of their quality across all data processing pipelines (Pre-Clinical, Clinical, Omics & RWD) from ingest to making data accessible for disease-centric multimodal analysis & investigation as well as being responsible for enabling “Data Findability” through a data FAIRification process by providing the required structured data with integrating advanced ontology management and metadata standardization (e.g., MedDRA, SDTM, ADaM, WHODrug & ISO taxonomies) enabling advanced patient cohorting & analytical functionalities. The Semantics Technologies lead will also be responsible for maintaining the data42 data catalog, designing and developing metadata management systems and shaping data42’s vision for how semantics can transform the landscape of multimodal & multidimensional data utilization in the R&D and medical continuum. About the Role Major accountabilities: Interface seamlessly with semantic experts across the company including the Biomedical Research (BR), Development (Clinical Operations & Analytics) and others. Establish and implement the multimodal data roadmap for data42 contributing to identify novel drug targets and therapeutic strategies. Apply all FAIR principles ensuring that all data assets are properly tagged, governed and aligned with business objectives and make any data understandable for data42 end users Maintain data catalog of all data assets managed across the data42 ecosystem Brings expertise and supports the implementation of the standardization of data models and reference data across all master data defined by each data assets owner. Maintain AI-enabled metadata tools to facilitate data findability and metadata management across all data assets and expose them to data42 end users. Lead and coordinate pipelines teams towards implementing data42’s vision for enabling disease-centric multimodal investigation. Coordinate closely with teams working on semantics and metadata standards across Novartis. In conjunction with a scrum master, run the team through an agile methodology ​ Experience/Professional requirements: Third level Degree qualification and 10+ years of professional experience in metadata management, semantic technologies, ontology, Artificial Intelligence (AI), and insights generation, within the pharmaceutical, biotechnology, or a related industry. In-depth knowledge of industry standardization like CDISC (SDTM, ADaM, SEND), HL7 FHIR, MedDRA, and WHODrug. Demonstrated experience in leading and implementing large-scale data projects and initiatives, particularly those involving semantic technologies, ontologies, and knowledge graphs. Proficiency in FAIR (Findable, Accessible, Interoperable, and Reusable) data principles and their application in a business/biomedical context. In-depth knowledge of Ontological authoring & engineering e.g. ontology development process, ontology life cycle, methodologies, tools and languages required for building ontologies. Knowledge of Generative AI and Large Language Models (LLM), with a focus on leveraging these technologies to transform unstructured and unharmonized data sources into insightful and actionable information. Semantic Web Technologies (Web 2.0/3.0, RDF/OWL/SKOS, SPARQL...) and their application to the biomedical domain (OBO). Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Novartis is at the forefront of medical research and bringing innovative and life changing medicines to millions of patients. Animal research is key to many of the great medical advances of today and animals play an integral part in the discovery and development of innovative, safe and life-saving medicines for patients. The Basel Head of Animal Welfare and Integrity Assurance (AW&IA) will lead, manage, and evolve the internal animal care and use program oversight for Biomedical Research Basel. About the Role Novartis upholds the highest standards and ethics of Animal Welfare and research, with steadfast commitment to the 3Rs principles (Reduction, refinement, Replacement), as well as introducing further improvements including the ‘4th R’ of Responsibility and our Biomedical Research sites all earning independent, international Gold Standard accreditation from the Association for Assessment and Accreditation of Laboratory Care (AAALAC). The Head of Animal Welfare and Integrity Assurance will ensure that all work involving research animals at Biomedical Research Basel is in compliance with Swiss laws and the Novartis Animal Welfare policies and standards. The role will include responsibilities such as liaising on behalf of Novartis Biomedical Research with regulatory authorities, accreditation bodies, and external groups and championing animal welfare and the 3Rs, as well as advocate for the critical role of animals in biomedical research. Your Responsibilities will include but not be restricted to: Lead internal oversight of the Biomedical Research Basel animal care and use program, including acting as site’s Lead Animal Welfare Officer and key contact for all in vivo users, regulators, and accreditation bodies. Direct Biomedical Research Basel AW&IA activities as Site Head to achieve efficient, consistent, compliant, and continuous improvement of animal care and use oversight operations, including: management and support of the license review and animal number reporting process post-approval monitoring program semi-annual inspections and program reviews investigation of reported animal welfare concerns/non-compliances ensure appropriate management of the Animal Welfare Body meetings as chair and all related preparation, facilitation, administration and follow-up actions serve as key contact to in vivo leadership including to the Institutional Official, Basel Pharmacology Council, and Basel Leadership Team support the development of the new animal management system Serve as named main point of contact for regulatory and accreditation needs, including both announced and unannounced inspections, communication with the Cantonal and Federal veterinary authorities, for documentation/information (e.g. lead AAALAC program description and site visits), and reporting out to agencies on applicable timelines (e.g. annual reports, ad hoc event reporting) Lead and manage direct reports in local AW&IA team, ensuring their development and appropriate time management. Act as a key contributor to the Global AW&IA team representing the Basel site to the Ethical Review Council, Global 3Rs Working Group and Global Risk Review teams Promote the 3Rs via leadership or delegated leadership of the local 3Rs Working Group including promotion of the 3Rs Awards programs and Innovation in 3Rs Granting program Together with colleagues in Public Affairs, promote openness and education about the continued need for and value of animal research through internal and external collaborations and communication, including participation in direct political stakeholder engagement. Minimum Requirements – what you will bring to the role: Education : University degree (PhD, Vet med, Med) in biology, veterinary medicine or medicine. Special knowledge in laboratory animal science and alternative methods. Authority approved study director role in Switzerland Experience in regulatory compliance and working as an Animal Welfare Officer in Switzerland, leading an IACUC or animal welfare body Experience: At least 5 years experiences in animal experimentation and leading and managing personnel in an in-vivo research environment Experienced in leading and managing a team of Direct and indirect Reports in a complex matrixed research and operations pharma industry environment Knowledge in public relations and Professional experience in communicating about and supporting advocacy efforts for the need for animal research to internal and external audiences highly desirable Experience working collaboratively with regulators and accreditation bodies Experience in supporting 3Rs (reduce, refine, replace animal studies) programs Languages: English and German fluent, proficiency in e.g. French would be of advantage. Desirable Continuous improvement skills and experience in using evidence to design and test improvements to programs and processes, including advancing AI and automation in licensing and reporting Experience in assessing animal care and use programmes requiring larger laboratory animal species, including Non-Human Primates (NHP), Pig, and Dog Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Der CBC Equipment Specialist ist verantwortlich für den GMP-konformen Herstellungsprozess von Zellbanken im Basel Cell Bank Center. Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role Major Accountabilities Teilnahme an den Herstellungsprozessen Durchführung aller notwendigen Verarbeitungsschritte des Zellbankwesens mit höchstemKenntnisstand der aseptischen/niedrigen Keimbelastungstechnik (Auftauen, Zellpassage,Zellzählung und Einfrieren der Zellbank) Ausführung sämtlich zugewiesener Tätigkeiten gemäß dem Produktionsplan und der gültigenGMP-, Arbeits-,Betriebs-, Umwelt- und Sicherheitsanweisungen und -richtlinien Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagenund -räume Verantwortung für die Haushaltsführung des Produktionsbereichs (Reinigung, Ordnung, 5S, usw.) Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien(HSE) Anwendung und Durchsetzen der aktuellen GMP-Regeln Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften Education: Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen, Technischer Abschluss; Universitatsabschluss (Chemieingenieurwesen, pharmazeutische Technologie, Biotechnologie, Biochemie) fur einige Technologieplattformen erwOnscht oder gleichwertige Erfahrung Languages: Grundkenntnisse in Englisch und Beherrschung der Landessprache des Standorts - German Experiences: Mindestens 2 Jahre abgeschlossene Berufserfahrung als Novartis-Gerätebediener oder (vorzugsweise) 5 Jahre in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Clinical Development Medical Director (CDMD) is the clinical leader of a section of a clinical program (e.g., an indication, a new formulation, or a specific development phase), or a large, complex trial, under the leadership of the (Sr.) GPCH. About the Role Your responsibilities include, but are not limited to: Provide clinical leadership and medical strategic input for deliverables in the assigned project/program. Deliverables may include sections of individual protocols consistent with the IDP, data review, program specific standards, clinical components of regulatory documents/registration dossiers, and publications (e.g., IBs, Brochures, briefing books, safety updates, submission dossiers, and responses to Health Authorities) Drive execution of the section of the program in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates Oversee/conduct medical and scientific review of trial data with Clinical Scientific Expert(s). May be the Program Manager of other associates (e.g.., CSE). May function as study medical monitor Support SR/GPCH in ensuring overall safety of the molecule. May be a core member of the Safety Management Team (SMT), and supports program safety reporting (e.g., PSURs, DSURs, and safety related documents) in collaboration with Patient Safety Support the Therapeutic Area Head (TAH) by providing medical input into IDP and CTP reviews and contributing/driving development of disease clinical standards for disease areas. Provide support to the (Sr.) GPCH or TAH in interactions with external partners (e.g., regulatory authorities, KOLs, data monitoring boards, AD Boards, patient advocacy groups), internal partners (e.g., CTT, Research, Translational Medicine, GMA, Marketing, HE&OR), and decision boards) Work with BR (Biomedical Research)/ Translational Medical Sciences) to drive transition of pre-PoC projects to DDP and with BD&L including target identification and due diligences together with additional matters Ensure career development of Program reports and clinical colleagues through active participation in performance management and talent planning processes. Provide on-boarding, training, & mentoring support Contribute to medical/scientific training of relevant Novartis stakeholders on the disease area and compound/molecule. May serve as speaker for franchise. May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) Minimal Requirements: MD (or equivalent medical degree) is required. Medical Board certification preferred. 4+ years Clinical practice experience (including residency) is preferred Possess advanced knowledge and clinical training in a medical/scientific area (e.g., internal medicine or sub-specialty) is required. 5+ years’ experience in clinical research or drug development from the pharma/biotech industry spanning clinical activities in Phases I through IV. 3+ years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting, and publishing) in a global/matrix environment Showcase advanced knowledge of assigned therapeutic area Demonstrate ability to establish strong scientific partnership with key partners Need thorough knowledge of GCP, trial design, statistical analysis methodology, and regulatory/ clinical development process Have people management experience preferred, this may include management in a matrix environment. Global people management is preferred. Exhibit excellent business communication and presentation skills Possess strong interpersonal skills Adept with excellent negotiation and conflict resolution skills Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Are you a highly skilled and ambitious medical professional with a passion for research? If so, we have an exceptional opportunity for you! Novartis, a world-class pharmaceutical company, is seeking a Clinical Development Medical Director - Renal to join our team in Switzerland. As a Research role, this position offers a unique chance to contribute to groundbreaking medical advancements in the field of renal medicine. About the Role Novartis is seeking a highly qualified Clinical Development Medical Director - Renal **80-100% to join our exceptional team in Switzerland or the UK. As a world-class pharmaceutical company, Novartis is dedicated to improving global health through groundbreaking research and innovative solutions. Responsibilities: Lead the clinical development activities for renal disease therapeutic area, ensuring flawless execution of clinical trials. Collaborate with cross-functional teams to design and implement clinical development plans. Provide medical expertise and guidance throughout the clinical development process. Successfully compete clinical trial protocols, investigator brochures, and informed consent forms. Determine appropriate safety monitoring and risk management strategies. Ensure compliance with all applicable regulatory and ethical guidelines. Contribute to the preparation and submission of regulatory documents. Analyze and interpret clinical trial data to support decision-making. Participate in scientific conferences and present clinical trial results. Requirements: Medical degree and experience in Nephrology or a related field. Proven experience in clinical development within the pharmaceutical or biotech industry. Strong knowledge of renal diseases and related therapies. Excellent understanding of clinical trial design and execution. Exceptional communication and interpersonal skills. Ability to work effectively in a cross-functional and multicultural environment. Strong leadership and project management abilities. Proficiency in English, both written and spoken. Novartis offers a unique opportunity for a CDMD to contribute to innovative research and make a significant impact on patients' lives. Joining our team means working with individuals who demonstrate exceptional problem-solving skills and a dedication to collaborative work in a dynamic and driven environment. At Novartis we are committed to fostering diversity and inclusion. We are an equal opportunity employer (EOE) and value the contributions of individuals from all backgrounds. We strive to provide a work environment that promotes fairness, respect, and equal opportunities for growth and development. We also understand the importance of reasonable accommodations and adjustments for individuals with disabilities. If you require any accommodations or adjustments throughout the application process, please let us know, and we will ensure that your needs are met. Join a leading organization committed to revolutionizing healthcare through advanced research and inventive solutions. Apply today and contribute to our impactful work! Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. As a Clinical Program Leader, you have the critical responsibility to lead and coordinate planning, execution, and interpretation of oncology early phase clinical trials. About the Role 6000! That's the number of associates in the BioMedical Research (BR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients! In Translational Clinical Oncology, we are global disease, modality, and trial experts in oncology early development. Our mission is to deliver innovative therapies through deep understanding of cancer biology, pioneering study design, agile evidence-based decision making, and collaborating with the scientific and medical community to accelerate new medicines for patients. This role is to provide strategic medical guidance and lead the development of experimental oncology agents in the TCO portfolio, from the Phase of preclinical development, continuing through clinical First in Human and Phase 1b/2 studies. Your responsibilities will include but are not limited to: • Acts as a clinical leader responsible for assigned global clinical program(s) -driving medical strategy implementation and operational deliverables for investigational products in a defined therapeutic area • Ensure effective cross-functional communications to align with global strategy and leads the development of clinical sections of trial and program level regulatory documents • Acts as the medical expert, engages interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders • Contributes to medical/scientific training of relevant Novartis stakeholders. May serve as speaker for medical/scientific training -May serve on or lead global initiatives (e.g., process improvement, training, SOP development, other Clinical Development line function initiatives) • Experience leading early and/or late phase Oncology clinical programs from the pharma/biotech industry plus credible experience from an academic medical center. • Track record of significant contributions to your field over time, creating new concepts and seeking out new clinical discovery opportunities approaches Role Requirements : What you'll bring to the role: ∙ Medical degree, oncology board certified preferred, and PhD level basic Science or equivalent expertise ∙ Essential requirement is Clinical Development experience within the pharma/biotech industry in Oncology. ∙ ≥ 3 years technical, operational and managerial experience in planning, executing, reporting and design of clinical trials studies in a pharmaceutical company or biotech. ∙ Good knowledge of Good Clinical Practice, clinical trial design, statistics, regulatory processes, and global clinical development process ∙ Good knowledge of oncology and experience in early clinical development preferred. ∙ Good communication, writing and organization and skills, fluent in English written and spoken Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive : You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility & Accommodation : Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary ROLE LOCATION: Basel, Switzerland ROLE Type: Full-time Onsite, #LI-onsite We are currently recruiting a Principal Scientist with a strong background in Cryo-Electron Microscopy (Cryo-EM) (Cryo-EM) to join our team in Basel, Switzerland. This position offers a unique opportunity to contribute to a dynamic and collaborative research environment. The ideal candidate will bring scientific curiosity, strong motivation and a collaborative mindset, along with excellent organizational and communication skills. About the Role Job Purpose Biomedical Research at Novartis is committed to pioneering innovative approaches that lead to transformative therapies for patients. The Discovery Sciences department at Novartis plays a critical role in early-stage drug discovery, driving the development of novel therapeutics to address complex and challenging disease targets. Within Discovery Sciences, the Protein Sciences group is a collaborative team of experts dedicated to producing and characterizing proteins using biophysics, NMR, X-ray crystallography and Cryo-Electron Microscopy (Cryo-EM). These efforts enable target-based drug discovery and support the identification of promising therapeutic candidates. Your responsibilities will include: Perform day-to-day operations within the EM group from maintaining and operating high-end electron microscopy to structure determination, modeling and interpretation of biologically and therapeutically relevant targets. Collaborate closely within the Protein Sciences group and cryo-EM colleagues at Novartis globally. Stay up to date with the latest developments in cryo-EM technologies. Mentor and train new users in EM techniques and best practices. Maintain detailed records of experiments, instrument logs, and maintenance activities. Minimum requirements Ph.D. in a relevant scientific discipline with 5 years experience or equivalent relevant research experience in an academic setting and/or in the pharmaceutical/biotech sector Strong background in cryo-EM techniques including sample preparation, single-particle analysis, and modeling. Excellent communication and presentation skills in oral and written English, German and/or French. Desirable Requirements: Proficiency in scripting and automated processing workflows. Ability to troubleshoot and optimize cryo-EM data pipelines for single-particle analysis. Familiarity with AI-based tools for construct design. Experience with expression, purification and modification of a range of protein targets. Experience in cryo-electron tomography and dual-beam scanning electron microscopy. Why Novartis?: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are looking for a currently enrolled Master student and can offer the rare opportunity to write a Master's thesis in our Data Science and Analytics Department. The task in a nutshell: Define the Data architecture of a solution elaborated in a project leveraging existing patterns. About the Role Data Architect - Internship We are looking for a Data Architect Intern to join our project team. The ideal candidate will have a strong understanding of data flow diagrams, data modelling, and data dictionaries. They will be responsible for designing consistent and efficient storage, integration, and access to data across the development process. Preferred Start Date : ASAP Duration : 6-12 months Key responsibilities: Design and maintain data flow diagrams, data models, and data dictionaries. Develop and implement data integration processes to combine data from multiple sources into a unified view. Establish relationships between data entities and set rules and standards for integration and interoperability. Ensure efficient data management and effective analysis/reporting to support business goals. Collaborate with various departments to ensure data architecture aligns with organizational objectives. Work Arrangement : Hybrid Minimum Requirements: Education : Currently enrolled in a Master's Degree in Computer Science, Information Technology, or a related field. Experience/Professional Requirements : Proven experience in data architecture, data modelling, and data integration processes. Desirable Requirements : Experience with data governance and metadata management. Familiarity with data storage solutions and data management tools Skills: Business Architecture. (Relito, Immuta) Enterprise Architecture. (Colibra) Data Quality (Ataccama) Data Governance. Solution Architecture. (databricks on AWS) Languages : Proficiency in English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are in search of a Director/Senior Director, Health Technology Assessment (HTA) Biostatistics, with statistical expertise in HTA and Pricing and Reimbursement activities. This role offers the chance to provide statistical solutions to HTA problems. The successful candidate will work closely with International Value & Access and HEOR teams to shape ways of working for Joint Clinical Assessment in Europe to ensure high-quality deliverables. About the Role Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people’s lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities – all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and welcome to where we thrive together! The Role 200+ compounds in Novartis are supported by biostatisticians in 10+ sites around the globe. Biostatisticians transform clinical data into analyses that build the basis for making innovative drugs accessible for patients. They influence decision-making in cross-functional international teams from early to late phase drug development. We are in search of a Director/Senior Director, Health Technology Assessment (HTA) Biostatistics, with statistical expertise in HTA and Pricing and Reimbursement activities. This role offers the chance to provide statistical solutions to HTA problems. The successful candidate will work closely with International Value & Access and HEOR teams to shape ways of working for Joint Clinical Assessment in Europe to ensure high-quality deliverables. Come to an industry leader where you will lead implementation of modern and innovative trial/experimental designs, statistical models, analysis and data exploration methodologies at the project level. Key Accountabilities: Accountable for strategic statistical input and influence into one or more projects (clinical development plan, integrated evidence generation strategy, publication strategy, market access strategy, pricing & reimbursement strategy) Lead implementation of efficient and innovative statistical methodology in HTA (indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.), reimbursement activities, clinical trials, and observational research to accelerate patient access considering requirements across the globe (Europe, Asia Pacific and other geographies). Lead collaborations with Health Economics and Outcome Research, Market Access, and other strategic functions to drive quantitative decision making in assigned indications/program. Plan, prioritize and oversee project level activities and ensure efficient resource management within or across franchise and effective partnership with vendors. Support responses to payer requests and/or interactions. Actively contribute to internal and external scientific interactions with decision making agencies and healthcare professionals. Responsible for all statistical work, scientific and operational, in collaboration with cross-functional and cross-regional partners. Ensure quality, timely and consistency of statistical deliverables, organizational learning, and knowledge through consistent application of processes & best practices. Support selection of external vendors and oversee them for outsourced activities Keep up to date with industry trends, advancements in HTA, and innovative statistical methodology (particularly in methods applicable to observational research area of HTA) to maintain proficiency in applying new and varied methods and to be competent in justifying methods selected. Communicate statistical findings and recommendations to non-statistical stakeholders in a clear and understandable manner. Develop and mentor biostatisticians on statistical methodologies and processes. Your experience: PhD with experience preferred or MS with experience with a degree emphasis in in Statistics, Mathematics or equivalent quantitative field Advanced knowledge of applying statistics (especially indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.) and innovative approaches in experimental design and causal inference method. Expertise in HTA, reimbursement process and regulations, including key decision drivers and review processes for key international markets and strong understanding of regulatory authority processes, and drug development. Ability to manage parallel multiple projects in different therapeutic areas Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary At data42, our vision is to inspire collaborative, groundbreaking data and AI initiatives that reimagine drug discovery at Novartis and accelerate time to market—ultimately transforming healthcare and improving lives. We are a dynamic team committed to this mission by enabling secondary research and data-driven decisions through scientific support and analysis-ready data, all within a secure, governed, AI-enabled platform. The Semantic Technologies Lead (Director Level) is responsible for setting the strategic vision and leading the implementation of semantics and metadata standards within data42. This role is accountable for the integrity, scalability, and impact of semantic frameworks across data42’s Pre-Clinical, Clinical, Omics, and Real-World Data pipelines, enabling disease-centric multimodal analysis and investigation. The Director ensures that all semantic initiatives within data42 are closely aligned with Novartis’s broader R&D and enterprise data strategies, while driving innovation and excellence from within the data42 organization through structured metadata and advanced ontology management (e.g., MedDRA, SDTM, ADaM, WHODrug, ISO taxonomies), driving data FAIRification and supporting sophisticated patient cohorting and analytical capabilities. In addition to overseeing the evolution of metadata systems and the data42 data catalog, this position plays a critical role in enhancing AI-driven projects and guiding the transformation of data42 into a next-generation AI-enabled program and will act as a strategic enabler of semantic technologies to unlock the full potential of multimodal and multidimensional data across the R&D and medical continuum, while maintaining strong alignment with enterprise-wide standards and objectives. About the Role Major Accountabilities Advise data42 and Novartis R&D leadership on data and AI strategy, risk, and investment, and communicate complex technical concepts to non-technical stakeholders. Manage large, cross-functional teams and budgets within data42, fostering a culture of innovation, collaboration, and high performance. Represent data42 in cross-functional and enterprise-wide working groups, standards bodies, and relevant external forums, ensuring data42’s needs and innovations are well integrated and recognized. Lead the development and deployment of AI-enabled metadata tools and knowledge graphs to facilitate data findability, semantic enrichment, and advanced analytics within data42. Champion the adoption and operationalization of FAIR data principles within data42, ensuring all data assets are properly tagged, governed, and aligned with both data42 and enterprise business and scientific objectives. Oversee the strategic evolution and governance of the data42 data catalog and metadata systems, ensuring comprehensive coverage, accessibility, and regulatory compliance of all managed data assets. Lead the design, build, and operationalization of scalable, cloud-based data and analytics platforms—including data lakes, catalogs, and ontology management solutions—within data42, supporting the full drug development lifecycle. Serve as the primary liaison between data42 and enterprise-level data and semantic governance bodies, ensuring that data42’s frameworks, standards, and tools are interoperable and consistent with company-wide objectives. Set and execute the semantic and metadata strategy for data42, ensuring all initiatives are fully aligned with the broader Novartis R&D and enterprise data strategy, while proactively fostering a culture of innovation within data42 to deliver transformative, next-generation solutions. Experience / Professional Requirements Advanced degree (PhD or equivalent) and 15+ years of progressive experience in metadata management, semantic technologies, ontology engineering, AI, and insights generation within the pharmaceutical, biotechnology, or related industry, including at least 5 years in a senior leadership role. Deep expertise in industry standards such as CDISC (SDTM, ADaM, SEND), HL7 FHIR, MedDRA, and WHODrug, with a proven track record of applying these in large-scale, complex data environments within R&D or clinical settings. Demonstrated leadership in designing, building, and operationalizing department-level or cross-functional data initiatives involving semantic technologies, ontologies, and knowledge graphs, with a focus on driving innovation and aligning with broader enterprise data strategies as the most senior semantic technologies leader within data42. Strong proficiency in FAIR data principles and their operationalization in biomedical and business contexts, with experience championing FAIR adoption within a department or program. Advanced knowledge of ontology authoring and engineering, including lifecycle management, methodologies, tools, and languages for building and maintaining ontologies at scale. Proven ability to lead and inspire multidisciplinary teams, manage budgets, and influence stakeholders at all levels, including executive and enterprise partners. Familiarity with Generative AI and Large Language Models (LLMs), with a focus on transforming unstructured and unharmonized data into actionable insights and enabling AI-driven innovation within a department or program. Expertise in Semantic Web technologies (e.g., RDF, OWL, SKOS, SPARQL) and their application to biomedical domains, including OBO Foundry ontologies. Experience serving as a liaison between a department/program and enterprise-level data governance or standards bodies, ensuring alignment and interoperability. Exceptional communication, stakeholder management, and change leadership skills. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Job Description Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Radioligand Therapies (RLTs) and xRNA Therapüeutics, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Scientist design, plan, perform and document scientific lab experiments for the preparation and timely development of drug product formulations and manufacturing processes in collaboration within a multifunctional project team coordinated by a Project leader. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Key Responsibilities: Design, plan, perform, interpret, and report results of scientific experiments for the preparation and timely delivery of drug product formulation and manufacturing process Lead and manage all project/local network activities, support team members, participate in project teams, and contribute to overall TRD strategies and goals Conduct experiments related to formulation and process development of oligonucleotides or RLT Communicate and address problems, perform literature searches under moderate guidance Contribute to the maintenance of lab instruments Contribute to transfer of processes to non-GMP and GMP manufacturing facilities Review and approve batch documentation, support deviations. Ensure adherence to HSE rules and guidelines. Required Qualification: Bachelor’s or Master’s degree (preferred) in Chemistry, Pharmaceutical Science, or a related field. A minimum of 3 years of experience in the pharmaceutical industry working on parenteral product development. Skills: Technical Knowledge: Expertise in parenteral drug product formulation and process development. Familiarity with oligonucleotide and peptide therapeutics, as well as radioligand therapies. Experience with lab techniques and tools like lyophilization, spray drying, analytical equipment, and autoclaves. Scientific and Analytical Skills: Ability to design, plan, perform, and document scientific experiments for drug formulation and process development. Troubleshooting and interpreting experimental outcomes, with the ability to conduct literature searches. Process Development: Knowledge of transferring processes to GMP and non-GMP manufacturing facilities. Experience reviewing and approving batch documentation, supporting deviations, and ensuring compliance. Collaboration and Teamwork: Comfortable working in multifunctional project teams and contributing to overall development strategies. Communication Skills: Strong verbal and written communication skills, including the ability to present ideas clearly and write scientific/technical documents. Computing Skills: Familiarity with software tools and computer systems relevant to laboratory work. Attention to Compliance : Adherence to Health, Safety, and Environment (HSE) guidelines and rules to maintain a safe and effective workspace. Languages : Fluent English (spoken and written) is required. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Join the Pharmaceutical Development (PHAD) Specialty Unit as an Associate Director – Drug Product Project Leader (DPPL) for drug product formulation and process development of parenteral innovative medicines, especially xRNA therapeutics and radioligand therapies (RLT). Advance the technology platform for both xRNA and RLTs and contribute to the development of patient-centric drugs. The position is ideal for an individual who is passionate about bringing transformational medicines to patients and working on exciting novel pharmaceutical products. The PHAD Specialty Unit is seeking an experienced Drug Product Project Leader (DPPL) to lead DP development sub-teams, be accountable for the DP development project strategy and represent DP development in the global CMC project team! Apply now and be a part of a team that is revolutionizing drug product development. About the Role Responsibilities As Drug Product Project Leader be the strategic lead of complex Drug Product Development projects (e.g. for Oligonucleotides or RLTs) within the PHAD Specialty Unit Lead and manage all formulation and process development activities for parenteral formulation development and parenteral manufacturing. Represent DP project teams in global CMC teams, providing strong quality awareness, scientific expertise, and project management skills. Develop a sound DP project strategy, including contingency planning and risk assessments, in line with overall Technical R&D project plan and guidelines. Monitor project plans and ensures timely availability of agreed timelines. Contribute actively to network deliverables and cross-functional initiatives, promoting collaboration and knowledge sharing. Act as an author, reviewer, or approver for PHAD owned documents, supporting submission writing and addressing inspection requirements. Ensures adherence to the EP/ LP project review process and high-quality documentation through relevant governance boards. Leads the Transfer Team and clinical development activities in alignment with TDP for late phase and LCM projects. Leads and / or contributes actively to respective Network deliverables and cross-functional workstreams/initiatives. Assesses, consolidates and negotiates resource needs (internal & external costs) and timelines. Lead budgeting process for DP activities. Requirements Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Technology or related disciplines with 7+ years of industry experience in parenteral drug product development, e.g. for Oligonucleotides (mRNA, siRNA, ASO) or Biologics (ADC, proteins), OR Master's degree with 9+ years of biopharmaceutical industry experience. Broad and profound understanding of development activities and processes in pharmaceutical sciences (parenteral, aseptic, solution, and/or suspension) Strong knowledge of laboratory and/or technical tools ((e.g., Quality by Design, statistical software, Process Analytical Technology). Familiarity with devices such as pre-filling syringes, vials, and combination products is an advantage. Strong scientific leadership skills. Basic / Advanced skills in Data Analysis and Data Visualization, including application of data science tools Strong knowledge of relevant GLP, GMP regulations and policies requirements in parenteral Drug Product development and manufacturing. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ausführung der zugewiesenen Aufgaben und Tätigkeiten in der biopharmazeutischen Produktion unter Einhaltung der relevanten GMP-, Arbeitssicherheits- und Umweltrichtlinien. Operative Routinetätigkeiten um den Herstellprozess fachgerecht durchzuführen und die zeitgerechte Bereitstellung von Wirkstoff in korrekter Qualität und Quantität zu ermöglichen. About the Role 1. Mitarbeit im biopharmazeutischen Herstellungsprozess im Schichtbetrieb 2. Ausführung aller zugewiesenen Tätigkeiten unter Einhaltung der gültigen GMP-, Arbeits-, Betriebs-, Umwelt- und Sicherheitsanweisungen und –richtlinien. 3. Anleitung von neuen Mitarbeitern während des on-the-job Trainings / Einarbeitungszeit. 4. Verantwortliche Durchführung einzelner Prozessstufen (Vorbereitung, Durchführung, Abschluss). 5. Ordnungsgemäße und zeitgerechte Reinigung, Vorbereitung und Sterilisierung der Produktionsgeräte und Produktionsräume 6. Durchführung von zugewiesenen Produktionsservicetätigkeiten (z.B. SAP-Buchungen, Dokumentenvorbereitung und –prüfung, Unterstützung bei Wartungsarbeiten) 7. Probenzug, Aliquotierung, Verteilung und Durchführung von ln-Prozesskontrollen 8. Durchführung des delegierten Umgebungsmonitorings für Reinräume und der delegierten Bemusterung von Reinstwasser und Reindampf 9. Organisation von Sofortmaßnahmen im Störungsfall, Melden von Auffälligkeiten an den Vorgesetzten 10. Ausführung aller zugewiesenen Tätigkeiten unter Einhaltung der GMP-, Arbeitssicherheits- und Umweltrichtlinien 11. Exzellente Dokumentation der Tätigkeiten gemäß GMP-Vorschriften 12. Einsatz für kontinuierliche Verbesserung 13. Ordnungsgemäßer Umgang mit biologischen und chemischen Substanzen in der Produktionsanlage 14. Bereitschaft zur kontinuierlichen Verbesserung und Schwachstellenanalyse 15. Teilnahme an allen für die Stelle relevanten Schulungen, Pflege der entsprechenden Trainingsnachweise 16. Voranbringen und Erhaltung eines HSE gerechten Umfelds: Melden von Beinahe-Unfällen Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Internal job title: Expert Regulatory Writer As an Expert Regulatory Writer, you will be responsible for authoring, reviewing, and managing the production of high-quality clinical documentation for submission to regulatory authorities in support of clinical trial and marketing applications. You will serve as a subject matter expert, providing authoritative consultancy on documentation-related matters to other departments, and mentoring less experienced writers. This position is part of the Regulatory Writing and Submissions (RWS) team and reports directly to the Unit Head. #LI-Hybrid About the Role Key Responsibilities: Independently author, review, and manage high-quality clinical documents, including Clinical Trial Protocols (CTPs) and amendments, complex Clinical Study Reports (CSRs), and CTD submission documents (e.g., clinical overviews, summaries of clinical efficacy and safety, clinical pharmacology and biopharmaceutics summaries), as well as other regulatory documents (e.g., briefing books, responses to Health Authority questions). Lead writing teams for complex submissions , contributing to key messaging and pooling strategies, offering expert guidance on clinical content, and ensuring compliance with internal standards and external regulatory requirements. Act as a member of Clinical Trial Teams (CTTs), leading the Protocol and CSR sub-teams, core member of Clinical Submission Teams (CSTs), and extended member of Global Clinical Teams (GCTs). Provide input into the planning and presentation of data analyses (e.g., review of statistical analysis plans and participation in related meetings) for use in CSRs, submission documents, and responses to regulatory queries. Ensure documentation compliance with internal standards and external guidelines while providing strategic and content expertise for the CTP and clinical sections of the CTD. Serve as Program Writer for large and/or complex programs , liaising with clinical teams and internal management to ensure adequate medical writing resources and consistency across documents. Lead and contribute to RWS practices and process improvements within RWS and cross-functionally. Coach and mentor junior writers. Facilitate cross-functional communication to ensure effective feedback and input for high-quality documentation. Maintain compliance with audit requirements, SOPs, and training standards. Essential Requirements: Academic degree in life sciences, healthcare, or a related field; an advanced degree is preferred. Full professional proficiency in English (native or near-native level). Several years of experience in medical writing or relevant pharmaceutical industry roles, with strong scientific and regulatory knowledge and expertise in medical writing processes. In-depth understanding of the global regulatory environment, including key Health Authorities, clinical trial design principles, documentation requirements, approval processes, and safety reporting. Proven experience and success in global drug registration. Strong knowledge of biostatistics principles. Excellent communication skills and experience working in a matrixed organizational environment. Demonstrated ability to prioritize and manage multiple projects and demands, and to solve complex problems effectively. Track record of successfully managing global, cross-functional teams or complex international projects. Proven ability to motivate and influence team members. Why Novartis? Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Disclaimer*: Some restrictions on flexible working options may apply and will be discussed during interview if applicable You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve. Hiring decisions are only based on the qualification for the position, regardless of gender, ethnicity, religion, sexual orientation, age and disability. The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Adjustments for Applicants with Disabilities: The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10058957 Sep 04, 2025 Switzerland Summary Internal job title: Expert Regulatory Writer As an Expert Regulatory Writer, you will be responsible for authoring, reviewing, and managing the production of high-quality clinical documentation for submission to regulatory authorities in support of clinical trial and marketing applications. You will serve as a subject matter expert, providing authoritative consultancy on documentation-related matters to other departments, and mentoring less experienced writers. This position is part of the Regulatory Writing and Submissions (RWS) team and reports directly to the Unit Head. #LI-Hybrid About the Role Key Responsibilities: Independently author, review, and manage high-quality clinical documents, including Clinical Trial Protocols (CTPs) and amendments, complex Clinical Study Reports (CSRs), and CTD submission documents (e.g., clinical overviews, summaries of clinical efficacy and safety, clinical pharmacology and biopharmaceutics summaries), as well as other regulatory documents (e.g., briefing books, responses to Health Authority questions). Lead writing teams for complex submissions , contributing to key messaging and pooling strategies, offering expert guidance on clinical content, and ensuring compliance with internal standards and external regulatory requirements. Act as a member of Clinical Trial Teams (CTTs), leading the Protocol and CSR sub-teams, core member of Clinical Submission Teams (CSTs), and extended member of Global Clinical Teams (GCTs). Provide input into the planning and presentation of data analyses (e.g., review of statistical analysis plans and participation in related meetings) for use in CSRs, submission documents, and responses to regulatory queries. Ensure documentation compliance with internal standards and external guidelines while providing strategic and content expertise for the CTP and clinical sections of the CTD. Serve as Program Writer for large and/or complex programs , liaising with clinical teams and internal management to ensure adequate medical writing resources and consistency across documents. Lead and contribute to RWS practices and process improvements within RWS and cross-functionally. Coach and mentor junior writers. Facilitate cross-functional communication to ensure effective feedback and input for high-quality documentation. Maintain compliance with audit requirements, SOPs, and training standards. Essential Requirements: Academic degree in life sciences, healthcare, or a related field; an advanced degree is preferred. Full professional proficiency in English (native or near-native level). Several years of experience in medical writing or relevant pharmaceutical industry roles, with strong scientific and regulatory knowledge and expertise in medical writing processes. In-depth understanding of the global regulatory environment, including key Health Authorities, clinical trial design principles, documentation requirements, approval processes, and safety reporting. Proven experience and success in global drug registration. Strong knowledge of biostatistics principles. Excellent communication skills and experience working in a matrixed organizational environment. Demonstrated ability to prioritize and manage multiple projects and demands, and to solve complex problems effectively. Track record of successfully managing global, cross-functional teams or complex international projects. Proven ability to motivate and influence team members. Why Novartis? Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Disclaimer*: Some restrictions on flexible working options may apply and will be discussed during interview if applicable You-ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse team-s representative of the patients and communities we serve. Hiring decisions are only based on the qualification for the position, regardless of gender, ethnicity, religion, sexual orientation, age and disability. The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Adjustments for Applicants with Disabilities: The law provides for severely disabled / equal applicants the opportunity to involve the local representative body for disabled employees (SBV) in the application process. If you would like to request this, please let us know in advance as a note on your CV. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (link is external) Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Universal Hierarchy Node Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Drug Product Project Leader (FPL) to lead drug product formulation and manufacturing process development. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Major accountabilities: Be accountable for all formulation and manufacturing process deliverables including scientific documentation, design of experiments of parenteral products, batch records, deviations, change controls, CAPAs, tech transfer, and reports. Drive DP development, manufacturing process transfers and supply activities with scientific and technological excellence Work closely with cross functional teams both internal and external to provide technical input for the development and manufacturing process (including CRO and CMOs). Provide technical support to compile technical regulatory documentation and responses to regulatory agencies as needed. Assist with writing and reviewing of CMC documentation associated with project or manufacturing changes. Key Skills Formulation Expertise: Experience developing injectable drugs, including solutions, suspensions, and aseptic formulations. Knowledge of RNA-based therapies (e.g., siRNA, mRNA) and drug delivery systems like pre-filled syringes or vials. Process Development : Skills in designing manufacturing processes and transferring them to production environments. Familiarity with aseptic drug manufacturing and methods like QbD. Regulatory Knowledge: Understanding of GMP and preparing technical documentation for regulatory submissions. Analytical Thinking: Designing experiments (e.g., DoE) and analyzing data to improve formulations and manufacturing processes. Collaboration & Communication: Strong teamwork skills for working with internal teams and external partners (e.g., CROs/CMOs). Clear communication and ability to write reports, technical documents, and regulatory responses. Problem-Solving: Ability to handle deviations, implement corrective actions, and improve manufacturing processes. Innovation: Interest in advancing RNA drug delivery platforms and contributing new ideas to the field. Preferred Technical Experience Working knowledge of oligonucleotide-based therapies (e.g., ADCs, proteins, RNA-based drugs). Familiarity with process development for clinical-grade parenteral drug products. Proven experience in related fields such as pharmaceuticals, biotechnological product development, and advanced drug delivery platforms. Required Qualifications: Ph.D., Master’s or Bachelor’s Degree in Chemistry or related disciplines: With 2+ years (Ph.D.), 5+ years (Master’s), or 8+ years (Bachelor’s) biopharmaceutical experience. Proven expertise in formulation and manufacturing process development for parenteral and aseptic products. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059955 Aug 19, 2025 Switzerland Summary Join our team in Pharmaceutical & Analytical Development (PHAD) and be a part of cutting-edge parenteral drug product development. Contribute to the advancement of novel technology platforms such as Oligonucleotides, and work on the Novartis main Campus in Basel. This is your chance to make a significant impact in the biopharmaceutical field and be at the forefront of bringing life-changing medicines to patients worldwide. The PHAD specialty Unit is seeking an experienced Formulation Drug Product Project Leader (FPL) to lead drug product formulation and manufacturing process development. Apply now and be a part of a team that is revolutionizing drug product development. About the Role Major accountabilities: Be accountable for all formulation and manufacturing process deliverables including scientific documentation, design of experiments of parenteral products, batch records, deviations, change controls, CAPAs, tech transfer, and reports. Drive DP development, manufacturing process transfers and supply activities with scientific and technological excellence Work closely with cross functional teams both internal and external to provide technical input for the development and manufacturing process (including CRO and CMOs). Provide technical support to compile technical regulatory documentation and responses to regulatory agencies as needed. Assist with writing and reviewing of CMC documentation associated with project or manufacturing changes. Key Skills Formulation Expertise: Experience developing injectable drugs, including solutions, suspensions, and aseptic formulations. Knowledge of RNA-based therapies (e.g., siRNA, mRNA) and drug delivery systems like pre-filled syringes or vials. Process Development : Skills in designing manufacturing processes and transferring them to production environments. Familiarity with aseptic drug manufacturing and methods like QbD. Regulatory Knowledge: Understanding of GMP and preparing technical documentation for regulatory submissions. Analytical Thinking: Designing experiments (e.g., DoE) and analyzing data to improve formulations and manufacturing processes. Collaboration & Communication: Strong teamwork skills for working with internal teams and external partners (e.g., CROs/CMOs). Clear communication and ability to write reports, technical documents, and regulatory responses. Problem-Solving: Ability to handle deviations, implement corrective actions, and improve manufacturing processes. Innovation: Interest in advancing RNA drug delivery platforms and contributing new ideas to the field. Preferred Technical Experience Working knowledge of oligonucleotide-based therapies (e.g., ADCs, proteins, RNA-based drugs). Familiarity with process development for clinical-grade parenteral drug products. Proven experience in related fields such as pharmaceuticals, biotechnological product development, and advanced drug delivery platforms. Required Qualifications: Ph.D., Master-s or Bachelor-s Degree in Chemistry or related disciplines: With 2+ years (Ph.D.), 5+ years (Master-s), or 8+ years (Bachelor-s) biopharmaceutical experience. Proven expertise in formulation and manufacturing process development for parenteral and aseptic products. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Bringing life-changing medicines to millions of people, Novartis sits at the intersection of cutting-edge medical science and innovative digital technology. As a global company, the resources and opportunities for growth and development are plentiful including global and local cross functional careers, a diverse learning suite of thousands of programs & an in-house marketplace for rotations & project work. With strong medicines pipeline our current transformation will not just deliver growth for our business but continue to allow us to bring innovative medicines to patients quickly. The Global Clinical Imaging and Analytics Head will coordinate and lead the application of different imaging strategies to support our portfolio of innovative medicines spanning across oncology, cardiovascular, renal, immunology, and neuroscience. Will coordinate with cross-divisional multidisciplinary teams spanning clinical, data science and commercial functions to discover, develop, evaluate and implement innovative AI/ML derived imaging biomarkers/endpoint strategies across the Novartis portfolio. This role will collaborate extensively with internal and external stakeholders to access/leverage medical imaging data/platforms and build a Novartis high value portfolio and reputation in the fields of imaging technology and clinical radiology. About the Role Major accountabilities: Develop fit for purpose clinical imaging strategies/technologies for our clinical trials and ensure high quality training at clinical sites and to data acquisition Develop and lead unique Novartis strategies for mining internal and external medical image and device data to support innovative biomarker discovery, development and implementation in drug development across multiple therapeutic areas Leverage diverse knowledge and skillsets to fully integrate and effectively communicate with clinicians, epidemiologists, data scientists, imaging experts and software engineers to meaningfully advance translational research efforts, including integration into disease animal models and other “omics/phe-nomics” data sets, where appropriate, across multiple therapeutic areas Lead AI/Machine learning approaches to develop novel structural and functional biomarkers/endpoints from medical imaging and device data to enable better quantitation of common clinical parameters or improve diagnostics, sub-classify diseases and enable predictive patient risk/stratification Lead and partner to enable impact of data science derived imaging biomarker approaches in the early drug development portfolio for “Proof of Concept/Proof of Mechanism” with Translational Medicine across multiple therapeutic areas Partner and serve as a leadership team member with NVS data platform groups e.g. DATA42/Data Sciences and AI, to clarify the landscape of clinical needs, challenges and the scope of imaging/DICOM data available to enable new analytic approaches with existing radiology software suites as well as de novo deep learning models at the voxel level Collaborate with internal stakeholders to support the advancement of imaging data repositories and data collection technologies such that the data are of maximal value to NVS systems and processes. Shape NVS policies on imaging data storage, aggregation, harmonization, retention and application so that it is well positioned to benefit NVS now and in the future Lead collaborations with internal stakeholders across NVS e.g. Biomedical Research/Development - clinical, data sciences, Chief Digital Office/AI Innovation Center/DATA42 to fully leverage enterprise imaging and data science expertise, optimize our portfolio value and drive innovation Team management and responsibility for a group of 10-30 Associates Key performance indicators: Lead the discovery, advancement and qualification of specific imaging based biomarkers/endpoints which can deliver personalized medicine approaches across Novartis portfolio spanning over research and development programs, providing the highest value added medicines Enable BR and Dev to test biological and therapeutic hypotheses in clinical development, resulting in clear proof of concept/mechanism readouts, health authority endorsements, and commercial differentiation, potentially helping in successful program acceleration. Recognized internally and externally through publications, leading global strategies/teams and consortium impacts as a subject matter expert/leader for NVS Adherence to Novartis Values and Behaviors, especially innovation and collaboration Education/Experience : PhD/MD, preferably MD, board certified radiologist with clinical research and data sciences training and/or certification, as well as a deep understanding of clinical epidemiology that can be applied to questions of diagnosis, biomarker development and treatment monitoring 5 to 10 years professional/industry experience Extensive Clinical and Diagnostic Radiology experience in areas such as Cardiovascular, Immunology, Neurology, Renal and Oncology Experienced in medical multi-modality imaging platforms such as MRI, CT, PET and ultrasound Substantial impactful global experience developing and leading multidisciplinary matrix teams across Pharma/biotech (clinical research through healthcare applications), academic institutions, and commercial business functions Demonstrated technical and scientific expertise in multiple areas for development of innovative biomarker solutions Well-developed interpersonal skills with good presence and ability to influence and negotiate with senior leadership, experienced presenter and communicator Recognized internally and externally by key stakeholders; in depth understanding of external environment/trends; develops a strong professional network Languages: Fluent in oral and written English Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards its-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland or Cambridge, MA, USA The Global Head of Modeling and Simulation (M&S) is a strategic scientific leader responsible for shaping and executing the global modeling and simulation strategy across all therapeutic areas—from early research to development. This role leads a high-performing team of expert modelers in the Pharmacokinetics (PK) Science department, driving productivity and decision-making in drug discovery and development. The Global Head will works closely with key departments within Research (including Preclinical Safety, Data and Digital, Pharmacology, Chemistry, and Biologics) and beyond (including Advanced Quantitative Sciences, Technical Research Development to ensure quantitative integration of disease, target, and compound knowledge—enhancing internal decision-making, contributing to submissions to health authorities, and increasing the probability of success for development candidates. About the Role Major accountabilities: Lead the M&S organization with responsibility for the management, allocation, and development of all M&S associates and resources and attracting and retaining top talent. Develop and champion a strategic vision to best implement and integrate the four M&S sub teams across data science, translational modeling and quantitative systems pharmacology (QSP), PBPK, and non-clinical statistics. Direct, supervise, and manage portfolio of M&S contributions to integrate relevant drug discovery and development, technical, and target / compound / disease area knowledge in the planning and execution of robust development programs and disease area strategies. In the Discovery & Preclinical Phases , M&S: M&S function to provide comprehensive support from early discovery to first-in-human clinical entry. Develops systems pharmacology platforms to guide early drug design for optimal therapeutic outcomes. Models biological targets and pathways to assess biomarkers, efficacy, and toxicity. Expands Artificial Intelligence approaches to optimize drug design across multiple therapeutic modalities and across therapy areas. Deploys statistical approaches to maximize impact of preclinical studies. In Clinical Ensure strong PBPK contributions to generate mechanistic insights on drug disposition and evaluate the impact of intrinsic and extrinsic factors on drug exposure. Expand PBPK applications beyond small molecules to support broader translational insights. Integrates preclinical and clinical biomarker and competitor data to develop mechanistic models to support FIH dose decisions. Expands the use of mechanistic models in clinical development to inform trial design and regulatory submissions through collaboration with the data and AI and pharmacometrics groups. Supports regulatory documentation and strategy. Drive the data strategy covering access, use, and storage of data used by and produced by M&S Anticipate organizational needs for M&S and strategic support based on in-depth understanding of the relevant issues and the drug development process. Identify opportunities and advocate and drive integration and implementation of innovation across the drug discovery and development continuum, such as next-generation M&S capabilities for new therapeutic modalities and emerging technologies such as digital twins & artificial intelligence. Lead infrastructure / process / scientific consulting improvement initiatives. Develop next generation M&S capabilities to serve new therapeutic modalities and emerging technologies such as digital twins and Artificial Intelligence. Provide on-boarding, training, mentoring and career development of staff, and oversee constructive and continuous performance evaluation. Member of the PK Sciences Leadership Team, contribute to overarching disciplinary and departmental strategy for PKS research and development across all Therapeutic Areas. Key performance indicators: Significant strategic and scientific impact on Biomedical Research projects and portfolio. Recognized as leading a team with best-in-class drug discovery and development M&S capabilities Develop next-generation M&S capabilities Development of staff, retention of high-performance associates, and driving a high-performance culture. Contributions to high functioning PK sciences Leadership Team Demonstrated and visible thought leadership through external visibility, reputation and shaping of industry practice. Minimum Requirements: Work Experience: Ph.D in pharmacology, biology, engineering, mathematics, statistics, computational science, or a field with significant modeling-related content (or equivalent Ph.D/MD) Skills: 15 years of relevant postdoctoral, academic, industry, or government experience with a track record as a leader and individual contributor in one or more of the following fields: Quantitative Pharmacology, Systems Pharmacology, Mechanistic Modeling, Physiologically based Pharmacokinetic Modeling, Disease Modeling, Pathway Modeling, Pharmacometrics. • Broad, integrative experience and a driven approach to the use of modeling and simulation in drug research and development. • Expert knowledge of drug discovery, drug development, and HA guidelines relevant to pre-clinical and clinical drug development. Substantial track record of identifying and leading contributions to policies that shape best practice in M&S. • Internal and external strong and established track record of establishing M&S excellence. • Excellent critical thinking and problem-solving skills. Strong record in leading global scientific improvement/change initiatives. • Significant experience in coaching, development, and influencing scientists and physicians Languages : English. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland or Dublin, Ireland. Data42 is Novartis’s data and analytics platform, that allows us to integrate different data modalities (discovery, preclinical, clinical, Real World Data (RWD)) at scale to support data-driven decision making across Novartis. We are seeking a Head of Data Engineering and Data Products to join our dynamic and innovative data and analytics team. This pivotal role is responsible for designing, building and maintaining data solutions using Palantir Foundry. In this role you will foster the use of AI/GenAI to advance the speed of high quality data delivery as well as to democratize the access to data and insights across the organization. The Head of Data Engineering and Data Products is a member of the Data42 Leadership team which comprises a Head of Data Science and Innovation, a Head of Platform as well as a Data Governance lead. In addition, this role will collaborate with key stakeholders across the Data and Digital Organization and across Novartis to ensure the rapid delivery of high quality data and data products with a team of ~50 internal and external team members. You will contribute to the overall success of Data42 as a member of the Data42 Leadership Team. This role will report directly to the Global Head of Data42. About the Role Your responsibilities include but are not limited to: Data Engineering Define the vision, lead and continue to develop our cross-functional Data Engineering and Data Products team by staying current with emerging technologies Responsible for architecting, designing, maintaining and optimizing complex data pipelines to support data exploration, operational workflows as well as advanced analytics Ensure best practices for data ingestion, processing, validation, transformation and storage Implement processes that guarantee data quality, integrity, security, compliance, and discoverability across platforms Advance the further use of automation and AI to accelerate the quality, speed and breadth of data delivery Data Products Accountable for designing, building and running scalable data product solutions using agentic workflows on Palantir Foundry to democratize data access with future needs in mind. Establish and action security and compliance policies to safeguard data access and dissemination Collaborate across the Data and Digital Organization as well as across Novartis. Support and ensure the flexible co-ordination of activities to deliver against timelines Delivery and Operations: Define and track key measurements for data systems and product success Oversee the project planning, delivery, and ongoing support for data engineering and product development Drive continuous improvement by monitoring system performance, analyze product data, and respond to feedback Essential Requirements: PhD or master’s degree in computer science or a related discipline with experience in pharma R&D with more than 10-15 yrs of experience in pharma or biotech Experience in data management, data engineering and data modelling, particularly in the design and implementation of efficient and scalable data models across different data domains with Clinical and RWD experience preferred Knowledgeable and experienced in CDISC data models/standards (i.e. SEND, SDTM, ADaM) and RWD data models/standards (i.e. OMOP) Experience with cloud platforms and cloud-based data and AI/ML solutions (Databricks, Snowflake, AWD SageMaker etc…) Strong enterprise mindset strategic thinker with a vision for data-driven decision-making from an end-to-end perspective Proven global cross-functional leadership skills including coaching and talent development, with the ability to influence stakeholders and drive organizational change within complex and ambiguous environments Excellent communication skills with proficiency in English (oral and written) Nice to have: Ideally proficient in Palantir Foundry to integrate, manage and analyze large data-sets Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards For Basel, Switzerland: Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary #LI-Hybrid Location: Basel, Switzerland Join our dynamic legal team as the Head of Finance Legal RoW, where you will play a pivotal role in shaping strategic decisions at the Novartis Group level. This is a unique opportunity to lead a talented team with impact— serving as a strategic legal advisor to senior leaders on Swiss and European capital markets, securities law, and corporate finance, while driving compliance and innovation in a fast-paced, global healthcare environment. About the Role Key Responsibilities Lead the Swiss Finance Legal team Provide strategic expert legal advice to, and contribute to the decision-making process of business partners, including but not limited to top and senior management, such as ECN members, Group Treasury, Global Tax, Global FRA, Global Head Investor Relations, in all aspects of financial law (e.g. legal advice relating to disclosure and reporting requirements, Swiss and European debt and equity capital markets transactions, asset management, investments and hedge funds, derivatives and treasury operations, financial structuring, capital allocation and corporate housekeeping) and Swiss company law Lead the processes for SIX filings and ad hoc disclosures coordinated at Novartis Group level Lead global, cross-divisional, cross-border and cross-functional complex transactions and regulatory projects requiring in-depth legal, finance and business knowledge Act as secretary, member and/or chair to, and attend meetings of, as needed, the boards of directors of strategically important Novartis subsidiaries and foundations, and exercise supervision, control activities and influence strategically important decision-making Ensure compliance and corporate governance of the activities of strategically important Novartis subsidiaries with applicable corporate laws and regulations and develop innovative solutions to challenges Ensure global compliance with financial regulations (e.g., EU Directives, SOX, IFRS standards and Swiss standards), including monitoring of regulatory changes and advising on implementation. Train and advise Business Partners on new legal trends, legislation and regulations in the Subject Matter Areas Instruct and supervise law firms providing advice to Novartis in the Subject Matter Areas and represent the interests of the Novartis Group in trade associations and other bodies Essential Requirements: University degree in law and admission to the Swiss bar Substantial working experience with expert level knowledge in all aspects of financial law and Swiss company law, including strong experience in transactional matters such as Swiss and European debt and equity capital markets, financing and other corporate finance related transactions Several years of experience in leading a team of lawyers Prior experience working in a top-tier law firm Excellent leadership, communication, and analytical skills paired with the ability to manage complex legal issues and provide clear, actionable advice Proficiency in English (written and spoken) Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Head of Data for Biomedical Research (BR) is responsible for developing and executing the Data and Digital (D&D) organization's data strategy to support research and early development. This role includes setting the vision for data utilization, managing data governance, and fostering a data-driven culture across the organization. The Head of Data will work closely with key stakeholders to ensure data quality, accessibility, and compliance across functions. As a member of the Research Informatics Leadership Team, this leader will report directly to the Global Head of Digital, Informatics, and AI. About the Role Major accountabilities but not limited to: Develop and implement comprehensive data strategies that align with business objectives and research priorities. Advise management on strategic direction, scope and approach. Promote and foster a data-driven culture, enhancing data literacy across the organization. Monitor and evaluate the effectiveness of data strategies, adjusting as needed to achieve desired outcomes. Stay informed about emerging trends and technologies in data management and apply innovative solutions to enhance data utilization. Establish and oversee data governance frameworks, ensuring high standards of data quality, accessibility, and compliance. Align on and contribute to Novartis Enterprise Data Management framework. Define and implement data standards, policies, and procedures, driving interoperability across systems and processes. Lead efforts to validate, review, and reconcile data, maintaining high-quality standards across all datasets. Integrate and harmonize data across multiple systems and functions, facilitating seamless data flow. Develop tools, workflows, and integration solutions to eliminate data silos and enhance collaboration across teams. Enable access to high-quality, reliable data for research and development teams to drive decision-making. Facilitate effective collaboration between data teams and business stakeholders, ensuring alignment with organizational goals. Build strong relationships with internal and external stakeholders, including external partners, to drive innovation and data-sharing opportunities. Communicate data strategies, insights, and recommendations to stakeholders at all levels of the organization. Lead a growing organization expected to reach 35+ people. Minimum Requirements: PhD or master’s degree in computer science, data science, AI, machine learning, or a related discipline. 15+ years of experience in data strategy, management, and governance, with a demonstrated understanding of advanced data methodologies applied to drug discovery and development in the pharmaceutical/biotech industry. Experience leading multidisciplinary, global teams and operating successfully in matrixed, fast-paced environments. Proven ability to manage complex portfolios and work with diverse stakeholders to prioritize resources and meet business needs. Strong leadership and communication skills, with the ability to influence stakeholders and drive organizational change. Strategic thinker with a vision for data-driven decision-making and a strong understanding of data management, governance, and analytics. In addition to traditional data management skills, the ideal candidate would possess competency in the following advanced data technologies: deploying scalable data solutions on cloud-native data platforms, experience with vector databases, implementing a decentralized, domain-driven data architecture, a solid grasp of ML Ops principles including the data centric aspects of model training, deployment and monitoring, experience implementing data observability tools, and familiarity with graph databases. Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Head of IMEX Program will spearhead the International Medical Excellence (IMEX) transformation program across Novartis International business unit, with special focus on the top 11 markets. This role demands a strategic and dynamic leader capable of driving the program’s vision, strategy, and execution, ensuring alignment with the overall business objectives. The IMEX Program Lead will work closely with the executive committee, IMA regional/country leaders, and cross-functional teams to optimize Medical Affairs practices and achieve significant growth, launch excellence and executional efficiencies in the key markets. About the Role Key Responsibilities: IMEX Program Leadership and Strategy: Lead the development and execution of the IMEX transformation program across all designated regions and markets. Collaborate with the executive committee to define and communicate the program’s vision, mission, and objectives. Develop a comprehensive roadmap for the IMEX program, including key milestones, timelines, and resource allocation. Design and implement program operating model, work architecture and governance that enables the transformation first for 4 key markets and then at scale for all international markets. Stakeholder Engagement and Management: Engage with senior leadership and key stakeholders to ensure alignment and support for the IMEX program. Foster strong relationships with regional and market leaders to facilitate the successful implementation of IMEX initiatives. Act as the primary point of contact for all IMEX-related activities and communications. Operational Execution: Oversee the roll-out of IMEX 1.0 across Wave 1, Wave 2, and Wave 3 countries, ensuring readiness and successful implementation. Bridge MarTech gaps and finalize MarTech workplan Coordinate with cross-functional teams, including GMA, DAP, TA, IT, and finance, to ensure integrated and efficient program execution. Identify, mobilize, and onboard relevant resources for Wave 1 roll-out (international and in-market) Implement and monitor key performance indicators (KPIs) to track progress and impact, making data-driven adjustments as necessary. Change Management: Lead change management initiatives to ensure smooth adoption of IMEX practices and processes within the organization. Develop and execute a communication plan to keep all stakeholders informed about program progress, successes, and challenges. Provide training and support to teams to enhance their capabilities and adoption of new tools and processes. Continuous Improvement: Identify and implement best practices to continuously enhance the IMEX program’s effectiveness and efficiency. Leverage data and analytics to gain insights and drive improvements in IMA strategies. Stay abreast of industry trends and innovations to keep the IMEX program at the forefront of Medical Affairs excellence. Talent and Culture Builds a high performing program team – with right capabilities, skills and mindsets Role model ICU and foster the culture that empowers with accountability, enables collaborations, and drives performance as ONE team Essential requirements: PhD or MD. Other degree like MBA or Project Management certification is a plus Minimum of 10 years of experience in Medical Affairs within the pharmaceutical or healthcare industry. Proven track record of leading large-scale transformation programs. Experience working in a multinational environment with cross-functional teams. Collaborative – fosters an Enterprise-first culture / mindset, demonstrates high emotional intelligence, connects cross-divisionally to build alignment across innovative ideas. Superior communication and interpersonal skills, with the ability to influence and engage stakeholders at all levels. Embraces and drives change, continually seeking ways to improve and innovate. Has track-record of operational innovation. Results-Oriented: Focused on achieving measurable outcomes and delivering value to the business. Proficiency in data analysis and performance management.Knowledge of AI and data-driven tools and techniques. Experienced people leader and maintains leadership role under pressure & during ambiguity.Strategic leadership - demonstrates the courage to assume personal accountability in challenging situations. Able to think broad and deep across different levers and align work to expected outcomes. High integrity – achieves objectives with high ethical standards. Location: This role is based in Basel, Switzerland. Benefits: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. About the Role We are offering a 6-month legal trainee position starting January 2026 to support the Novartis Procurement, Data/Digital &IT Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, antitrust law, intellectual property and disputes/litigation. This legal trainee position offers excellent opportunities to gain first-class, hands-on in-house legal experience within the stimulating, multinational environment of a leading pharmaceutical company. Duration: 6 months Start: January 1, 2026 Your responsibilities will include: • Support a diverse range of commercial matters relating to direct and indirect procurement, manufacturing, IT • Support diverse range of legal projects, e.g. contract templates, legal trainings, global legal research projects, digitalization, outsourcing, etc. • Assist with the drafting, negotiation and review of a variety of transactional, commercial and agreements • Draft legal memoranda on a wide variety of legal issues and disputes, Draft document and key position summaries • Provide legal advice to internal clients • You will be supervised and guided by a range of lawyers on different levels of the company, ensuring a great learning experience What you’ll bring to the role: Essential: • Swiss Law degree (Master of Law and Bachelor of Law has to be on Swiss Law), master's degree needs to be completed before start date • Business-level English skills (written and spoken), additional language is a plus • Interest in legal topics in a large multinational group of companies • High motivation to perform, to discover and learn new things and ability to work independently Desirable requirements: • Prior legal professional experience in a law firm, court or legal in-house department (internships etc.) would be helpful. We are also open to applicants without prior experience who have a strong interest and are motivated to learn on the job • Other professional experience in the corporate environment is a plus Please submit a cover letter that includes your motivation for the position and your availability to start in January 2026. Thank you. Why Novartis Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We offer a 6-month legal traineeship position in Legal for Corporate Functions, starting June 1, 2026! About the Role Are you interested in pursuing a career in law? We have the perfect opportunity for you! Our legal trainee position offers excellent hands-on, in-house legal experience within the dynamic and multinational environment of a leading pharmaceutical company. More than 70’000 unique individuals work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world. We are seeking a motivated and diligent legal trainee who has the courage to navigate in unknown and ambiguous legal areas and has the curiosity to learn and being exposed to interesting and challenging new legal questions. If you're passionate about making a difference and keen to kickstart your career with our in-house team, this could be the ideal role for you. We offer a 6-month legal traineeship position starting June 1, 2026 Your responsibilities include: • You'll be the backbone of our Legal team, offering essential advice in employment law (including questions related to Diversity, Equity & Inclusion), as well as litigation and investigation. You'll have the opportunity to tackle complex global and local issues, transforming challenges into solutions. • You'll get your hands on practical tasks, managing individual legal cases, but also major projects (reorganizations, divestments, implementation of new policies and processes, etc.), drafting and reviewing agreements, internal regulations, and templates. This is your chance to shift from theory to practical application, making an immediate impact. • Your role will involve in-depth legal research and the creation of legal memoranda, helping us to break down complex ideas into digestible insights. Here, your knowledge will fuel our mutual success. • You'll also play a pivotal role in reporting key legal matters to our audit committees in strict adherence to the Sarbanes-Oxley Act. What you’ll bring to the role: • Swiss Bachelor of Law (BLaw) und Master of Law (MLaw); master degree needs to be completed before start date • Excellent proficiency in English and German, both in verbal and written communication • High motivation and ability to work independently on challenging tasks and projects • Prior legal internship and knowledge in employment law is a plus Are you ready to sharpen your skills and inspire change? If you're excited to contribute and learn, apply now, and submit a cover letter that includes your motivation for the position and your availability for six months starting in June 2026. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben , and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary We are offering two 6-months legal trainee positions to support the Novartis Operations Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, M&A and licensing transactions, restructuring, antitrust law etc. Start dates: January 1 - June 30, 2026 and June 1 - November 30, 2026 About the Role We are offering two 6-months legal trainee positions to support the Novartis Operations Legal department on a wide range of legal matters and projects in areas such as contract law, commercial law, M&A and licensing transactions, restructuring, antitrust law etc. These legal traineeships offer excellent opportunities to gain first-class, hands-on in-house legal experience within the stimulating, multinational environment of a leading pharmaceutical company. Start dates: January 1 - June 30, 2026 and June 1 - November 30, 2026 Your responsibilities will include: • Support M&A and corporate projects, manufacturing and supply agreements, real estate projects, portfolio and manufacturing site divestments, including conducting due diligence, managing data rooms and enquiries in the sale process, and legal project management • Support a diverse range of commercial matters relating to the development, procurement, manufacturing, quality assurance and supply chain and distribution of pharmaceutical products • Support diverse range of legal department projects, e.g. contract templates, legal trainings, global legal research projects, digitalization, outsourcing etc. • Assist in drafting, negotiation and review of a variety of transactional, commercial and technical agreements • Draft legal memoranda on a wide variety of legal issues and disputes • Provide legal advice to internal clients, draft documents and key position summaries • Interact with Novartis global, regional and country legal network What you’ll bring to the role: • Education: Swiss Law degree (Master of Law and Bachelor of Law has to be on Swiss Law), master's degree needs to be completed before start date • Languages: Business-level English (written and spoken); German ideally and additional languages are a plus • Experience/Professional requirements: o Prior legal professional experience in a law firm, court or legal in-house department (internships etc.) would be helpful. We are also open to applicants without prior experience who have a strong interest and are motivated to learn on the job o Overall high motivation and ability to work independently Desirable requirements: • Other professional experience in the corporate environment is a plus Please submit a cover letter that includes your motivation for the position and your availability to start in January or June 2026. Thank you. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Ulcerative colitis and Crohn's disease, along with other gastrointestinal ailments, represent a diverse array of conditions impacting millions globally. These afflictions have significant unmet medical needs and often lead to a diminished quality of life. Novartis stands at the forefront of pharmaceutical innovation in immunology, leveraging advanced scientific research to develop transformative treatments that enhance patients' lives worldwide. We are seeking a Medical Director or Executive Director of Gastrointestinal (GI) Immunology in Translational Medicine Immunology. Join us in this endeavor! You will provide medical and scientific leadership and expertise in a role that significantly impacts the drug development pipeline. 1. Drive success of early global programs, develop and implement strategies to achieve Transition Decision Point (TDP) 2. Drive success of late global programs by developing and implementing strategies, which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling. 3. Support Translational Research in developing new indications, endpoints and biomarkers, using in vitro, in vivo, or in silico methods. 4. Provide scientific expert assessments and support for in-licensing opportunities, including due diligences. About the Role Major Accountabilities Early clinical projects (Phase I / II, “Discovery”): Develop, in collaboration with TM TA Head and work with teams to carry out, strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications, including post-indication expansion projects. Lead global project teams through phase I/IIa to drive implementation of the development strategy. Convene relevant (internal and external) experts to consider the proposed approach to reach TDP; present plans for approval at relevant decision boards. Be responsible for clinical portions of the Integrated Development Plan (IDP, including the Clinical Development Plan and Clinical Profiling Plan) Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Late-stage clinical projects (post-TDP, “Profiling”): In collaboration with TM TA Head or Translational Medicine Profiling Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs, representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection, study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials, such as special populations, drug-drug interactions, mechanism of action assessments, Pediatric Investigational Plan, etc. Drive analysis of studies and presents results to relevant decision boards. Communicate clinical team matters to GPTs and relevant BR and Development boards [and other Novartis Boards] Evaluate clinical centers and foster communication with crucial collaborating investigators, regulatory authorities, and other stakeholders. Be responsible for writing TM portion of documents needed for regulatory submission through drug registration (including advisory committee and scientific advice group meetings) Translational Research (TR; indication seeking, endpoint and biomarker development): In collaboration with TM TA Head, BR Research scientists, other TM line functions (BMD, CS&I, PCS, PKS), develop strategies to identify initial or expansion (PIE) indications, and to obtain sufficient evidence to fund these ideas. In collaboration with research scientists, identify, develop, and implement strategy for preclinical support of clinical program-related scientific objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities. This may include methodology studies to identify and validate novel endpoints for early decision making in Phase IIa studies. Be accountable for compound-related biomarker strategies; works closely with Biomarker Expert in implementation. Business Development and Licensing (BD&L; in-licensing and outlicensing compounds): Participate on BD&L teams as the TM representative. In collaboration with BD&L team, evaluate the risks and benefits of potential in-licensing opportunities, identifying the strengths and weaknesses of external programs in terms of TM’s scope of responsibility. Participate in teams carrying out out-licensing of BR programs, as subject matter expert for the disease indication, molecule, and clinical trial experience. Leadership: Lead study-specific teams/ clinical trial teams in partnership with other line functions. Lead BR-sub-team(s) on Global Project Teams for late-phase programs Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Man- agement) line functions to ensure operational excellence, continued urgency, and close attention to timelines, costs, and subject burden in balance with high scientific stand- ards and innovation. Key Performance Indicators Delivery of proposed Development Candidate ((B)DC) and Integrated Development Plan Approval (IDPA) milestones, and results driving decision-making for/against transition into later phase development (TDP), according to defined timelines. Delivery of Clinical pharmacology and profiling strategy including execution of studies according to timelines to support regulatory submissions and approvals. Delivery of TR plans, whether in vitro, in vivo, or in silico, to drive program strategy and clinical trial efficiency. Team leadership skills that create high performing teams and drive efficient conduct of innovative, interpretable clinical results and a focus on operational excellence at all levels. Strong adherence to and modeling of Novartis values and behaviors. Impact of this role? Design and implementation of early Integrated Develop- ment Plan (IDP) and design and implementation of studies according to the IDP, enabling efficient and rational decision-making, high probability of fast drug registration, favorable drug label and high competitiveness of compounds. This role has a key impact on the entire Novartis pipeline, transitioning programs from preclinical through early clinical and ultimately to full development via the TDP mechanism, and driving the program after TDP by delivering key Profiling data to support regulatory submissions. Recognized Expert in field, drives project team clinical strategy. Works globally across Novartis. Role Requirements : Education Doctoral degree, MD required in most cases. PhD or relevant scientific experience with academic track record preferred Demonstrated excellence and clinical expertise in relevant medical subspecialty. Experience/Professional Requirement: At least 5 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience. Recognized medical expertise, as evidenced by publication of significant contributions to a field over time. Excellent written and oral communication/presentation skills. Independence: Able to work independently as outlined above, commensurate with level of role. Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP. Demonstrated passion for science. Recognized expert in field, driving success for individual studies and projects; respected by colleagues across R&D, Development, and externally. Languages: Fluent English (oral and written). ABOUT TRANSLATIONAL MEDICINE: Translational Medicine is a global group of scientists and Physicians working at the pre-clinical and early clinical stage of drug discovery. Our Physician-Scientist Discovery & Profiling group drives innovative and cutting–edge science from Discovery to the market through the selection, profiling and effective global development of successful medicines. The group closes the gap between preclinical research and clinical development and integrates clinical science into the discovery and preclinical development phase. Our Translational Medicine concepts are driven by medical needs of the patient and the concept of personalized medicine, tailoring the drug, its dose and dosing regimen in such way to the patient that the clinical response is optimal in terms of efficacy and safety. We focus from identification of drug targets (molecular pathways relevant to disease) up to the completion of Proof of Concept (Phase IIa studies). Our Translational Medicine Experts are part of preclinical project teams in all drug discovery phases and help design the pathway for First in Human studies (healthy volunteer) that bridge to studies in the patient population. They have the comprehensive responsibility for designing and executing the early clinical drug development phase together with a project team from researcher, biomarkers, biostatistics, modeling and simulation, toxicology, technical experts and the clinical trial teams. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Co-supervised by Novartis Pharmacometrics Department and Uppsala University in Sweden. The INVENTS project consortium (https://invents-he.eu/), in which Novartis is an associated partner, aims at developing methods, workflows, and evidence-tools to improve the development and evaluation of evidence in rare diseases and pediatric populations. Pharmacometrics (PMX) models are often used to support drug development in these settings, however, there is limited research on when the dose response relationship inferred through pharmacometrics models has the intended causal interpretation. The aim of this project is to advance our understanding of the potentials and limitations of pharmacometrics modeling approaches from an estimand and causal inference perspective for the development of new medicines in small sample size populations such as rare diseases and pediatric populations. Preferred start date: ASAP Duration: 4 years About the Role Major accountabilities: Assessing types of intercurrent events that can impact the interpretation or even the existence of measurements of the efficacy or safety endpoint of interest in the target population. Assessing and contrasting strategies, including the required assumptions, to handle such intercurrent events. Developing causal inference methodologies adapted to pharmacometrics models, to identify valid estimators (i.e., yielding unbiased estimates) of the estimand. Developing tools such as model diagnostics that help assess whether a model can be interpreted causally. Performing simulation studies and analyze real clinical data to assess the impact and limitations of the proposed approaches on the evidence generated. Minimum Requirements: Master’s level degree or equivalent in a relevant field such as statistics, pharmacometrics, mathematics, engineering, biomedicine, or medicine, with strong interest in causal inference. Strong interest in bridging principles from causal inference and pharmacometrics. Good interpersonal and communication skills. Exposure to scientific computing and programming Desirable requirements: Expertise or coursework in causal inference. Expertise in R. Experience with modeling & simulation software such NONMEM or Monolix Suite. Languages : Fluency in English (IELTS (academic) total score of 6.5 or higher with no section less than 5.5), or equivalent. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a edical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060747 Aug 29, 2025 Switzerland Summary Co-supervised by Novartis Pharmacometrics Department and Uppsala University in Sweden. The INVENTS project consortium ( https://invents-he.eu/ ), in which Novartis is an associated partner, aims at developing methods, workflows, and evidence-tools to improve the development and evaluation of evidence in rare diseases and pediatric populations. Pharmacometrics (PMX) models are often used to support drug development in these settings, however, there is limited research on when the dose response relationship inferred through pharmacometrics models has the intended causal interpretation. The aim of this project is to advance our understanding of the potentials and limitations of pharmacometrics modeling approaches from an estimand and causal inference perspective for the development of new medicines in small sample size populations such as rare diseases and pediatric populations. Preferred start date: ASAP Duration: 4 years About the Role Major accountabilities: Assessing types of intercurrent events that can impact the interpretation or even the existence of measurements of the efficacy or safety endpoint of interest in the target population. Assessing and contrasting strategies, including the required assumptions, to handle such intercurrent events. Developing causal inference methodologies adapted to pharmacometrics models, to identify valid estimators (i.e., yielding unbiased estimates) of the estimand. Developing tools such as model diagnostics that help assess whether a model can be interpreted causally. Performing simulation studies and analyze real clinical data to assess the impact and limitations of the proposed approaches on the evidence generated. Minimum Requirements: Master-s level degree or equivalent in a relevant field such as statistics, pharmacometrics, mathematics, engineering, biomedicine, or medicine, with strong interest in causal inference. Strong interest in bridging principles from causal inference and pharmacometrics. Good interpersonal and communication skills. Exposure to scientific computing and programming Desirable requirements: Expertise or coursework in causal inference. Expertise in R. Experience with modeling & simulation software such NONMEM or Monolix Suite. Languages : Fluency in English (IELTS (academic) total score of 6.5 or higher with no section less than 5.5), or equivalent. Why Novartis: Our purpose is to reimagine medicine to improve and extend people-s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a edical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Others Job Type Full time Employment Type Early Career (Fixed Term) Shift Work No

Summary Location: Basel, Switzerland Full time, onsite, #LI-onsite We are seeking a highly motivated and experienced Principal Scientist II/Senior Principal Scientist to be a leader in our RNAi drug discovery efforts at Novartis' Biomedical Research labs at our Basel site. This is an exciting opportunity to be at the cutting-edge of xRNA therapeutics, and to play a strategic role in driving the development of RNAi-based therapies, leveraging a deep understanding of RNAi biology and chemistry to advance programs from concept to clinical development, in areas such as Liver, Renal and Metabolic diseases. The ideal candidate will combine exceptional scientific expertise with strong leadership and collaborative skills to contribute to our mission of delivering transformative therapies to patients. About the Role Your responsibilities will include: Lead and mentor a team of highly skilled molecular biology scientists at the Basel site, focusing on the design, screening, and characterization of RNAi-based therapies. Design, plan, and oversee siRNA cell-based screening activities, including assay development and optimization, with a focus on implementation of high throughput automation. Perform end-to-end RNA-Seq NGS experiments to assess off-target risks, including library preparation, sequencing, and data analysis. Expand research space for off-target assessment to advance safe siRNA therapeutics to clinic Define mid- and long-term goals, establish action plans, and implement strategies for the local xRNA team in alignment with the global xRNA and Biologics Research Center strategy. Co-lead RNAi drug discovery and development programs in collaboration with Global Discovery Chemistry and Disease Areas (DA) teams. Partner with downstream development colleagues to progress RNA lead candidates toward full development. Coordinate and align activities with other Global Biologics Research Center teams and functional groups . Collaborate with DA partners to identify unmet medical needs and enable the development of novel therapeutic solutions. Represent the xRNA team on cross-functional project teams, driving the advancement of siRNA programs through the development pipeline. Provide innovative solutions to scientific challenges and lead troubleshooting efforts. Provide supervision in the laboratory setting and talent development opportunities Minimum requirements: What you will bring to the role Ph.D. in a relevant scientific discipline, including genomics, molecular biology & biochemistry with a minimum of 5 years of experience in RNAi/oligonucleotide drug discovery, recognized as an expert in the field both internally and externally. Proven experience in RNAi drug discovery, including RNAi design, screening, and characterization. Comprehensive knowledge of RNAi chemistry and biology, with a focus on lead optimization of therapeutic candidates. Strong genomics expertise, including hands-on experience with RNA-Seq experiments, from library preparation to data processing and analysis. A demonstrated track record of success, as evidenced by high-quality publications and patents. Highly collaborative mindset, combined with strong communication skills, creativity, and the ability to manage multiple projects in a fast-paced environment. Excellent oral and written communication skills. Experience with extrahepatic targeting of RNAi is preferred. Expertise in lab automation is highly desirable. If you are passionate about leading cutting-edge research, thrive in a collaborative and innovative environment, and are eager to make an impact in delivering RNAi-based therapies to patients, we encourage you to apply. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated scientist to advance our mission to deliver transformative new therapies for patients with chronic diseases, with a special emphasis on liver diseases, in the Disease Area x (DAx) at the Novartis Biomedical Research (BR) facility located in Basel, Switzerland. In this position, you will identify and lead novel innovative therapeutic approaches to treat chronic diseases, such as liver diseases, ranging from target identification and validation to drug discovery and identification of candidate molecules towards clinical evaluation. A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In that role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. About the Role A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In this role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. Key responsibilities: Lead a group of scientists focused on preclinical activities related to the identification and validation of targets and drug candidate molecules for chronic illnesses, with a particular emphasis on liver diseases. Apply innovative in vitro/ex vivo models, which reflect human disease conditions, to identify drug candidates. Translate therapeutic concepts from preclinical models to patients and vice versa , including cutting-edge experimental approaches and application of data science tools. Strongly contribute and influence the strategic direction of liver research in DAx, stay up-to-day with latest developments in the field of liver diseases. Shape, mentor, and lead a high-performing team of scientists by fostering a collaborative environment and developing skills of team members. Navigate effectively in a matrix-based, cross-functional environment, collaborating across departments within Novartis Biomedical Research and beyond. Maintain a strong external network with academic institutions and manage external collaborations. Essential requirements: PhD/Postdoc in life science, such as cell or molecular biology or physiology. A minimum of 5 years in drug discovery for chronic diseases in an industrial setting with demonstrated expertise ranging from target identification toward clinical application. Possess an in-depth molecular understanding of physiology and disease pathophysiology, such as for liver diseases, and have expert knowledge of cell-based methods (primary cells, organotypic cultures, explants) to mimic disease conditions in vitro/ex vivo . Is highly proficient in state-of-the-art molecular, cellular and biochemical assay and profiling technologies, including – but not limited to – single-cell transcriptomics techniques. A deep understanding of data science and application of data science tools to evaluate complex datasets is highly desired. Proven leadership skills in managing and guiding teams effectively, including setting and evaluation of objectives, and advancing the development of people. Demonstrated ability to work independently and as part of a collaborative, interdisciplinary team of biologists, computational scientists, and translational research/medical scientists. Strong written and verbal communication skills, organizational skills, and excellent attention to detail. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059813 Aug 27, 2025 Switzerland Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite We are seeking a highly motivated scientist to advance our mission to deliver transformative new therapies for patients with chronic diseases, with a special emphasis on liver diseases, in the Disease Area x (DAx) at the Novartis Biomedical Research (BR) facility located in Basel, Switzerland. In this position, you will identify and lead novel innovative therapeutic approaches to treat chronic diseases, such as liver diseases, ranging from target identification and validation to drug discovery and identification of candidate molecules towards clinical evaluation. A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In that role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. About the Role A deep understanding of liver physiology and pathology is strongly desirable. You should possess advanced proficiency in cutting-edge molecular biology techniques, have expert knowledge of cellular tissue models and profiling technologies, and be adept at using data science tools to analyze complex datasets. In this role, you will be leading a team of experienced scientists and contribute to the strategic development of the liver therapeutic area and beyond. Key responsibilities: Lead a group of scientists focused on preclinical activities related to the identification and validation of targets and drug candidate molecules for chronic illnesses, with a particular emphasis on liver diseases. Apply innovative in vitro/ex vivo models, which reflect human disease conditions, to identify drug candidates. Translate therapeutic concepts from preclinical models to patients and vice versa , including cutting-edge experimental approaches and application of data science tools. Strongly contribute and influence the strategic direction of liver research in DAx, stay up-to-day with latest developments in the field of liver diseases. Shape, mentor, and lead a high-performing team of scientists by fostering a collaborative environment and developing skills of team members. Navigate effectively in a matrix-based, cross-functional environment, collaborating across departments within Novartis Biomedical Research and beyond. Maintain a strong external network with academic institutions and manage external collaborations. Essential requirements: PhD/Postdoc in life science, such as cell or molecular biology or physiology. A minimum of 5 years in drug discovery for chronic diseases in an industrial setting with demonstrated expertise ranging from target identification toward clinical application. Possess an in-depth molecular understanding of physiology and disease pathophysiology, such as for liver diseases, and have expert knowledge of cell-based methods (primary cells, organotypic cultures, explants) to mimic disease conditions in vitro/ex vivo . Is highly proficient in state-of-the-art molecular, cellular and biochemical assay and profiling technologies, including - but not limited to - single-cell transcriptomics techniques. A deep understanding of data science and application of data science tools to evaluate complex datasets is highly desired. Proven leadership skills in managing and guiding teams effectively, including setting and evaluation of objectives, and advancing the development of people. Demonstrated ability to work independently and as part of a collaborative, interdisciplinary team of biologists, computational scientists, and translational research/medical scientists. Strong written and verbal communication skills, organizational skills, and excellent attention to detail. *Restrictions on flexible working and reduced working time may apply and can be discussed at interview stage if required Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary #LI-Onsite We are looking for a dedicated QC Analyst to support Good 'x' Practice (GxP) activities in our quality department. This role involves managing quality systems, implementing operational processes, and ensuring compliance with Novartis quality standards. About the Role Key Responsibilities: Maintain compliance with current Standard Operating Procedures (SOPs), GxP-compliant documentation, and records within the Novartis quality management system. Perform and evaluate analytical tasks in a pharmaceutical laboratory, including working in shifts where necessary. Ensure the integrity of all quality assurance records and data, as applicable, and foster collaboration between your team and other functions and departments. Ensure an appropriate level of education and GxP knowledge. Support quality audits and health authority inspections. Essential Requirements: Experience in quality assurance and analytical skills. Proficiency in analytical technologies (e.g., HPLC, GC, titration). Knowledge in the use of lab-specific software (e.g., Empower, Chromeleon, TiAmo). GMP experience and technological expertise. Willingness to work in shifts. Fluency in German and English. This role is limited to 24 months. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) *Disclaimer: Some restrictions on flexible working options may apply and will be discussed during interview if applicable. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059577 Aug 11, 2025 Switzerland Summary #LI-Onsite We are looking for a dedicated QC Analyst to support Good 'x' Practice (GxP) activities in our quality department. This role involves managing quality systems, implementing operational processes, and ensuring compliance with Novartis quality standards. About the Role Key Responsibilities: Maintain compliance with current Standard Operating Procedures (SOPs), GxP-compliant documentation, and records within the Novartis quality management system. Perform and evaluate analytical tasks in a pharmaceutical laboratory, including working in shifts where necessary. Ensure the integrity of all quality assurance records and data, as applicable, and foster collaboration between your team and other functions and departments. Ensure an appropriate level of education and GxP knowledge. Support quality audits and health authority inspections. Essential Requirements: Experience in quality assurance and analytical skills. Proficiency in analytical technologies (e.g., HPLC, GC, titration). Knowledge in the use of lab-specific software (e.g., Empower, Chromeleon, TiAmo). GMP experience and technological expertise. Willingness to work in shifts. Fluency in German and English. This role is limited to 24 months. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture&nbsp ; Benefits and Rewards : Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards&nbsp ; Commitment to Diversity and Inclusion / EEO: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, be-cause of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) *Disclaimer: Some restrictions on flexible working options may apply and will be discussed during interview if applicable. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Befristet (Befristet) Shift Work No

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite At Novartis we are reimagining medicine to improve and extend people's lives. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. We are looking for a highly motivated, passionate researcher with a strong scientific background in radiochemistry, a curious mindset, and cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapy (RLT) . About the Role Key Responsibilities: Radioligand synthesis: Independently plan and perform the synthesis of radioligands (including LMW compounds, peptides, and protein-based vectors) using radionuclides such as Lu-177, Ga-68, and F-18, as part of a dynamic team of radiochemists in alignment with project goals. Method development: Develop, evaluate, and validate novel radiolabeling methods and formulation strategies to optimize processes. Quality control: Conduct quality control analyses of radioligands (e.g., HPLC, TLC, SEC) and ensure their readiness for preclinical in vitro and in vivo studies. Collaborative research: Collaborate effectively with multidisciplinary teams, including organic chemists, pharmacologists and cell biologists, to advance the characterization and development of radioligand therapies (RLTs) in oncology. Innovation: Explore and implement innovative technologies, including automation, to enhance efficiency in daily tasks. Radiation Safety: Adhere to radiation safety guidelines, including training, dosimetry monitoring, and proper handling and disposal of radioactive materials. Minimum Requirements - What You’ll Bring to the Role: Scientific expertise: A strong enthusiasm for hands-on experimental chemistry and radiochemistry, with the ability to interpret results critically, formulate new hypotheses, and design subsequent steps. Education: A master’s or bachelor’s degree or equivalent apprenticeship in chemistry, pharmacy, or a related field, with prior experience in radiochemistry and radiolabeling techniques (PhD is not required). Experience: At least 1-2 years of practical experience in a radiochemistry laboratory, along with proficiency in standard IT tools (e.g., E-Notebook, ChemDraw, and software-controlled lab equipment). Team-oriented approach: Passion for working in cross-disciplinary teams, exchanging scientific ideas, contributing to shared goals and learning from colleagues with diverse perspectives to advance future RLTs Mindset: Strong organizational skills, attention to detail, flexibility, and a commitment to delivering high-quality results. Technical proficiency: Familiarity with automated synthesizers for radiolabeling and purification is an advantage. Communication skills: Good written and verbal communication skills in English. Professional Growth and Development We are committed to fostering the professional growth of every team member. In this role, you will have the opportunity to develop and expand your expertise both scientifically and technically. Scientific Involvement : You will be actively involved in project teams, where you can engage intellectually, contribute your ideas, and help shape the direction of innovative projects. Technical Growth : You will have the chance to become an expert and go-to person for specific instruments, tools, or processes, making an impactful contribution to the team. As you grow in this role, you'll take on increasingly significant responsibilities, becoming a valued contributor to our team’s success. We believe in empowering our team members to thrive through collaboration, continuous learning, and meaningful challenges. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. *Please note that restrictions on flexible working may apply and will be discussed at interview stage if applicable Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10029829 Aug 15, 2025 Switzerland Summary The Neuroscience Department within BioMedical Research at Novartis Pharma AG in Basel, Switzerland, is searching for a motivated and experienced Research or Senior Scientist. This individual will assume a hands-on role within the in vivo neuroinflammation team and contribute to several research projects focused on the development of new therapies for neurodegenerative disorders, potentially helping improve the lives of millions of patients worldwide suffering neurodegenerative illnesses and conditions. The main focus will be on novel neuroimmune cell pathways to elucidate the mechanisms at the molecular, cellular and ex vivo/in vivo level. Joining our team you will independently but with close collaboration with the other members of the Neurosciences group plan, execute, document, analyze and interpret experiments. About the Role Your responsibilities will include: Designing, conducting and protocolling independently in vivo studies with specific focus on neuroinflammatory pathways Establishment of new in vivo models for neuroinflammatory/neurodegenerative diseases Performing and interpreting ex vivo analyses with emphasis on histology, biochemistry, FACS and molecular biology Development and execution of in vitro cellular assays for assessing inflammatory processes Presenting data and putting it in a complex context Supporting general laboratory duties Your profile: University degree (MSc) or equivalent qualification, preferably in neuroscience, immunology, cell biology. *Please note that PhD candidates will not be considered for this position* Minimum 2-3 years relevant lab based work experience in an industrial or academic setting Previous experience in neuroscience drug discovery area would be an advantage. Strong expertise in in vivo rodent work e.g. different routes of dosing, surgery, stereotactic brain injections, behavior, perfusion. Relevant animal experiment course available (e.g. LTK1) Experience in different histological methods, microscopy and image analyses Experience in RNA/DNA technologies and biochemistry, e.g. qPCR technologies, Westernblot Good knowledge of immunology and immunological methods such as flow cytometry, HTRF, ELISA Good knowledge in cell culture work, e.g. primary cells, iPSCs Used to evaluating large datasets, strong documentation capabilities and interest to use new informatics analysis tools Eager to learn and combine new techniques and concepts, to present results within the lab, to use and apply literature data, to perform exploratory activities and to work independently and as a team member Scientific curiosity, initiative, commitment, flexibility and good organization skills Track record of successful collaborations, open communication with different stakeholders, strong team player and networker Excellent oral and written English Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Biomedical Research Business Unit Pharma Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Part time Employment Type Regulär Shift Work No

Summary The Senior Clinical Development Medical Director (CDMD) is responsible for leading the strategic planning and management of the assigned clinical program(s) from an end-to-end clinical development perspective. As Sr CDMD in the Renal TA, you will have oversight of the clinical development for the assigned programs and drive execution of the clinical development plan. In addition, you will enable an empowered organization, which can navigate in a matrix environment and adjust quickly to business needs. About the Role Major accountabilities: Your responsibilities will include, but are not limited to: Providing clinical leadership and strategic medical input for all clinical deliverables in the assigned project or section of a clinical program Leading development of clinical sections of trial and program level regulatory documents Driving execution the assigned clinical program and/or clinical trial in partnership with global line functions, assigned Global Trial Directors (GTDs), and regional/country medical associates, where applicable Supporting (Senior) Global Program Clinical Head (GPCH) in ensuring overall safety of the molecule for the assigned section, and may act as a core member of the Safety Management Team (SMT), supporting overall program safety reporting in collaboration with Patient Safety colleagues Supporting the Clinical Development Head (CDH) by providing medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new disease areas As a medical expert, supporting the (Sr.) GPCH or CDH in interactions with external and internal stakeholders and decision boards May work with NIBR (Novartis Institute of Biomedical Research/ Translational Medical Sciences) to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed. Minimum Requirements: MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Clinical practice experience 4 years (including residency) and board certification or eligibility in disease area preferred Minimum of 10 years of experience in clinical research or drug development Experience in an academic clinical research or industry environment spanning clinical activities in Phases I through IV required. • 2 years of contribution to and accomplishment in all aspects of conducting clinical trials (e.g., planning, executing, reporting and publishing) in a global/matrix environment in pharmaceutical industry required. Working knowledge of disease area is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports Demonstrated ability to establish effective scientific partnerships with key stakeholders Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes Previous global people management experience is preferred, though this may include management in a matrix environment. Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: Novartis Life Handbook Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Without safe, easy-to-use, high-quality drug delivery systems our patients could not get their medicines. This is where you come in; the Device Technology Solution Center needs you as Senior Expert Engineering for the development of drug device combination products working alongside our talented, bright and diverse teams. Our Device Technology Solution Center drives the technical development of auto-injectors as well as novel drug delivery principles, e.g. drug delivery to the brain or radioligand therapy. We closely collaborate with project management, human factors engineers, packaging experts, analytical testing, production, external partners, regulatory experts and many more. The aim is to develop and/or integrate innovative drug delivery systems with drug formulation and author state-of-the-art technical documentation for health authorities and production. About the Role Your Responsibilities: Your responsibilities include, but are not limited to: Develop platforms and collaborate with cross-functional teams to deliver safe, user-friendly, and reliable products Lead and support teams in the field of assembly and injection molding for device/part design, equipment and process across from prototyping to commercial scale Create and maintain relevant Design History File (DHF) documents, ensuring high-quality device design and development Contribute to all phases of medical device development: ideation, prototyping, piloting, and manufacturing transfer Ensure components meet quality standards for clinical trials and commercial production Collaborate with external partners, including prototypers, toolmakers, and CMOs Identify root causes of issues, define and implement robust solutions Role Requirements Degree in mechanical engineering or equivalent Preferably 10 years of experience in medical device development Proficient spoken communication and excellent technical writing skills in English Proven experience in production of plastic and metal components Proven experience in assembly of plastic and metal components / sub-assemblies Proven experience in design for manufacturing and design for assembly Good knowledge in key regulations and standards (e.g. ISO 13485, ISO 23908, ISO 11608, ISO 10993, MDR, Design Controls) Ability to interact with cross functional team in matrix organization Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: Basel, Switzerland Role Purpose: Responsible for Engineering activities including planning and coordination of maintenance & calibration activities, project execution and continuous improvement at area of responsibility (e.g. buildings, process equipment, utilities, automation). About the Role Major Accountabilities: Strategy & Organizational Development: Ensures equipment operates to required HSE, Quality, Environmental and Reliability standards Lead or contribute to equipment, utility, facility improvement projects (e.g. energy efficiency, productivity, environmental compliance, maintenance) Support internal and external audits Maintenance & Calibration: Execute maintenance improvement projects and initiatives (local or corporate) Establish cost efficient repair and maintenance processes in compliance with local regulations, HSE, GMP Enter master data into CMMS (e.g. confirmation and technician time allocations) Supervise and Coordinate maintenance / calibration activities and plan relevant resources Project Engineering & Control: Prepare Equipment Specifications and System Requirements in project (e.g. User Requirement Specification) Prepare, review and approve drawings, lists, schedules, diagrams, layouts, calculations and datasheets in project Provide technical trouble shooting during PQ and validation Work Experience: Experience in pharmaceutical or chemical Industry is desired Experience in Plant Engineering Collaborating across boundaries Education: Degree in engineering (Dipl. Ing. / M. Sc. / B. Sc.) or equivalent Skills: Manufacturing Engineering Process Engineering Project Commissioning Project Engineering Project Management Applications (eg. COMOS / SAP / 1QEM / etc.) Languages : German English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10059479 Aug 20, 2025 Switzerland Summary Location: Basel, Switzerland Role Purpose: Responsible for Engineering activities including planning and coordination of maintenance & calibration activities, project execution and continuous improvement at area of responsibility (e.g. buildings, process equipment, utilities, automation). About the Role Major Accountabilities: Strategy & Organizational Development: Ensures equipment operates to required HSE, Quality, Environmental and Reliability standards Lead or contribute to equipment, utility, facility improvement projects (e.g. energy efficiency, productivity, environmental compliance, maintenance) Support internal and external audits Maintenance & Calibration: Execute maintenance improvement projects and initiatives (local or corporate) Establish cost efficient repair and maintenance processes in compliance with local regulations, HSE, GMP Enter master data into CMMS (e.g. confirmation and technician time allocations) Supervise and Coordinate maintenance / calibration activities and plan relevant resources Project Engineering & Control: Prepare Equipment Specifications and System Requirements in project (e.g. User Requirement Specification) Prepare, review and approve drawings, lists, schedules, diagrams, layouts, calculations and datasheets in project Provide technical trouble shooting during PQ and validation Work Experience: Experience in pharmaceutical or chemical Industry is desired Experience in Plant Engineering Collaborating across boundaries Education: Degree in engineering (Dipl. Ing. / M. Sc. / B. Sc.) or equivalent Skills: Manufacturing Engineering Process Engineering Project Commissioning Project Engineering Project Management Applications (eg. COMOS / SAP / 1QEM / etc.) Languages : German English Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Development Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Join a mission-driven team at Novartis as a Senior Intelligence Analyst, where you'll play a pivotal role in safeguarding our global operations, people, and reputation from a wide spectrum of criminal threats—ranging from cybercrime, the falsification and counterfeiting of Novartis products, attacks against travelling associates, unscrupulous vendors/counterparties, ‘insider’ threats regarding fraud and corruption to asymmetric threats from extremism, extortion, blackmail, bribery, indiscriminate terrorism and other criminal activity. This high-impact role not only leads intelligence operations and travel security programs but also empowers cross-functional collaboration and analytical excellence to protect what matters most. Let your expertise drive meaningful changes in a dynamic, global environment! About the Role Key Responsibilities: Deputize in the absence of the Head Global Security Intelligence, leading the day-to-day operational management of the Global Security Intelligence Unit (GSIU), tasks include: quality assurance of intelligence reports, negotiation of requests for intelligence reports, tasking of GSIU analysts Work on assigned priorities and to an agreed plan, manage the ‘intelligence cycle’ through the systematic collection, collation, evaluation, interpretation and analysis of information and process this into timely, accurate, and relevant intelligence.. Drive innovation to the analysis and understanding of root cause analysis and contribute to the wider training around its application. Lead the process of conducting Global Security Background Checks. Manage the process of global country risk mapping assessments (as part of the External Party Risk Management Process) across all regions through the collation of intelligence requests, procurement process for vendors, vendor and stakeholder management and quality review of the final product. Lead the global travel security and travel incident response program and advise/coach team members in complex analysis. Provide to the GSIU and wider Legal community peer-to-peer coaching and training, as well as on-boarding of new team members Responsibility for collation of submissions for Enterprise Risk Management and One Novartis Controls Environment for Global Security Alongside the Head of Global Security Intelligence manage knowledge and drive innovation within analysis to ensure high-quality, value-adding intelligence products Act as the single point of contact for external sources and agencies - to build a detailed intelligence picture regarding threats to Novartis. Essential Requirements: University degree in intelligence management, international corporate security, criminology or equivalent Deep expertise in career intelligence / investigations paired with a strong project management track record, ideally in a complex international company Proven experience in intelligence work applicable to role: e.g. counter-terrorism/ counter-extremism/ counter-narcotics / criminal investigations /other relevant area Significant working experience in a military, law enforcement and/or customs/security intelligence/commercial intelligence environment Outstanding written and verbal communications skills (e.g.. report writing / presentations) with the ability to influence at senior executive level Proficiency in English (written and spoken), other languages are a plus Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060264 Sep 04, 2025 Switzerland Summary Join a mission-driven team at Novartis as a Senior Intelligence Analyst, where you'll play a pivotal role in safeguarding our global operations, people, and reputation from a wide spectrum of criminal threats-ranging from cybercrime, the falsification and counterfeiting of Novartis products, attacks against travelling associates, unscrupulous vendors/counterparties, -insider- threats regarding fraud and corruption to asymmetric threats from extremism, extortion, blackmail, bribery, indiscriminate terrorism and other criminal activity. This high-impact role not only leads intelligence operations and travel security programs but also empowers cross-functional collaboration and analytical excellence to protect what matters most. Let your expertise drive meaningful changes in a dynamic, global environment! About the Role Key Responsibilities: Deputize in the absence of the Head Global Security Intelligence, leading the day-to-day operational management of the Global Security Intelligence Unit (GSIU), tasks include: quality assurance of intelligence reports, negotiation of requests for intelligence reports, tasking of GSIU analysts Work on assigned priorities and to an agreed plan, manage the -intelligence cycle- through the systematic collection, collation, evaluation, interpretation and analysis of information and process this into timely, accurate, and relevant intelligence.. Drive innovation to the analysis and understanding of root cause analysis and contribute to the wider training around its application. Lead the process of conducting Global Security Background Checks. Manage the process of global country risk mapping assessments (as part of the External Party Risk Management Process) across all regions through the collation of intelligence requests, procurement process for vendors, vendor and stakeholder management and quality review of the final product. Lead the global travel security and travel incident response program and advise/coach team members in complex analysis. Provide to the GSIU and wider Legal community peer-to-peer coaching and training, as well as on-boarding of new team members Responsibility for collation of submissions for Enterprise Risk Management and One Novartis Controls Environment for Global Security Alongside the Head of Global Security Intelligence manage knowledge and drive innovation within analysis to ensure high-quality, value-adding intelligence products Act as the single point of contact for external sources and agencies - to build a detailed intelligence picture regarding threats to Novartis. Essential Requirements: University degree in intelligence management, international corporate security, criminology or equivalent Deep expertise in career intelligence / investigations paired with a strong project management track record, ideally in a complex international company Proven experience in intelligence work applicable to role: e.g. counter-terrorism/ counter-extremism/ counter-narcotics / criminal investigations /other relevant area Significant working experience in a military, law enforcement and/or customs/security intelligence/commercial intelligence environment Outstanding written and verbal communications skills (e.g.. report writing / presentations) with the ability to influence at senior executive level Proficiency in English (written and spoken), other languages are a plus Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Legal Business Unit Corporate Location Switzerland Site Basel (City) Company / Legal Entity C010 (FCRS = CH010) Novartis International AG Functional Area Legal & Intellectual Property & Compl. Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary We’re a team of dedicated and smart people united by a drive to achieve together. Are you a passionate communicator ready to drive change and make a meaningful impact? You will support the development and execution of end-to-end communications strategy for the President Europe and be responsible for working with Director of Policy Comms & Media Relations to deliver regional thought leadership, enhanced external stakeholder engagement and reputational impact. You will drive the internal communications at the regional level for increased associate engagement and sense of belonging across Novartis Europe and advise senior management and collaborate with a range ofteams both internally and externally todrive impactful execution of communications activities. About the Role Key Responsibilities: Develop and execute an integrated communications strategy for President Europe. Support and enable external positioning of the Europe President to build influence, reputation, and thought leadership. Drive and execute internal communications strategies for Region Europe and President Europe to boost associate engagement and sense of belonging. Develop and coordinate content generation and briefings for President Europe’s formal communications e.g. speaking engagements, media opportunities, social media, organizational announcements. Manage multiple communications formats (verbal, audiovisual, and written) across internal and external channels. Work with external agencies to plan and execute internal and external programs designed to shape behaviours, reputation, and environments. Utilize a range of analytical and insight tools to inform practices and learnings, and set clear objectives, goals, strategies, and measures. Essential Criteria: Bachelor's degree in related area. Extensive experience in both internal and external communications Executive stakeholder communication and management Data-driven and embraces measurable action Social media strategy and management Track record of thriving in a large matrix organization English (C2 / fluent written and verbal) Desirable Criteria: Understanding of policy communication Media relations knowledge Pharma or Medical Device experience Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network(link is external) Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Lead innovative and impactful communications and patient advocacy for our Cardiovascular, Renal & Metabolic (CRM) Therapeutic Area across key international markets. Drive forward-thinking strategies that support brand launches and boost market impact in our top 11 global markets. Collaborate across functions to harness real-time insights, adapting approaches in a fast-evolving external landscape. Location: Basel, Switzerland #Hybrid About the Role Key Responsibilities : Lead and implement innovative CRM therapy area and product communications and patient advocacy strategies, with a focus on digital-first, data-driven campaigns that support pre-launch, launch, and in-market brand success. Drive impactful, value-based partnerships and co-creation initiatives with key stakeholders across the top 11 priority markets, leveraging digital platforms to scale engagement and outcomes. Apply the OGSM framework, KPIs, and advanced analytics to monitor, predict, and optimize product performance management above country and for Top 11 markets, ensuring agile decision-making aligned with Communications & Advocacy (CA) Strategy and Operations. Establish new and maintain strategic partnerships with relevant patient communities and groups, including management of grants and sponsorships. Provide strategic counsel and foster a culture of innovation by sharing best practices, insights, and measurement learnings across top 11 markets and Rest of World (ROW). Collaborate cross-functionally with International TAs, marketing, medical, value and access teams to align on integrated, digitally enabled strategies that drive business and patient impact. Develop and execute branded and unbranded omnichannel communications, patient engagement, and disease awareness campaigns—leveraging social media, digital storytelling, and emerging technologies to amplify reach and relevance to support business objectives to achieve patient and healthcare system impact. Design and deliver audience-centric programs that support pre-launch and growth brands, using real-time insights to continuously refine messaging, media strategy, and congress engagement. Monitor and anticipate key environmental, policy, and digital trends impacting the company’s operations across international geographies, ensuring alignment with an agile and forward-looking media relations strategy and implementation. Partner with agencies to co-create strategic, innovative, and digitally driven programs that resonate with stakeholders and deliver measurable impact. Ensure seamless implementation and compliance with systems and processes related to communications and patient advocacy—leveraging digital tools for transparency, reporting (e.g., ToV), and continuous improvement. Essential Requirements : Bachelor’s degree or equivalent experience. Proficiency in English required – spoken & written, other languages is an asset. Proven experience in diversified communications and patient advocacy, with a strong ability to influence and build trust-based, value-driven partnerships with patient communities and stakeholders. Demonstrated experience across multiple therapeutic areas, with a track record of applying innovative and digital-first approaches to engagement and strategy. Strong capability in predictive modelling and data-driven decision-making, using multidirectional insights to understand evolving environments, customer needs, and drive iterative, measurable experimentation. Excellent analytical and conceptual thinking skills, with the ability to translate complex data and trends into actionable, innovative strategies. Ability to navigate and simplify highly complex environments, providing strategic recommendations that balance innovation with business impact. Deep business and organizational awareness, with an enterprise mindset and a collaborative approach to cross-functional alignment. Hands-on experience in product PR communications, including the design and execution of social media strategies and digital campaigns. Solid background in corporate communications, investor relations, media relations, stakeholder engagement, and policy advocacy. Proven ability to manage crisis and issues communications, including agency collaboration and rapid response planning in dynamic environments. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary BDSS QC Bioanalytics is responsible for bioanalytical testing of Biopharmaceuticals for late-phase development projects and commercial products. Applied analytical techniques are mainly cell-based potency assays for bioactivity determination and ELISA /qPCR for the determination of process-related impurities (e.g. host-cell proteins (HCP), residual Protein A, residual DNA). About the Role We are looking for a motivated Senior QC Specialist (Lab Head) to supervise the performance of bioanalytical experiments (i.e. cell-based bioassays, ELISA and qPCR) for quality control (release, stability, and in-process control (IPC) testing) of biotech drug substances (DS) and drug products (DP) in collaboration with members of the own and cross-functional teams in a cGMP environment. Analytical method validation and transfers will be part of the position. Major Accountabilities of the role as Senior QC Specialist (Lab Head) include: • Supervision of routine QC testing activities, including line unit approval of analytical records and raw data, investigations of deviations, OOE/OOS, and analytical changes • Full compliance with regulatory and cGMP guidelines within the field of responsibility • Support of technical project teams as analytical expert • Performance of method validations (full ICH validation) and transfers, author of validation- and transfer protocols / -reports • Trending and evaluation of analytical data • Method lifecycle management for commercial products including method updates, post-approval changes, or troubleshooting • Management and coordination of internal and external customer interfaces (e.g. testing/resource requirements, setup of service level agreements) • Support in health authority inspections as subject matter expert (e.g. routine GMP inspections, pre-approval inspections) • System owner of laboratory equipment and computerized systems including initial qualification and periodic maintenance/functional testing Requirements: • PhD or equivalent education in Biology, Biochemistry, Chemistry, or related discipline • Several years of experience in analytics / quality control in a leadership role. Experience with Biopharmaceuticals desirable • Thorough knowledge of cGMP requirements • Results oriented, team player and able to work with all levels of the organization • Strong leadership and problem solving skills. Able to identify issues and develop business-friendly solutions in line with the overall compliance • Good knowledge of instrument qualification, quality metrics • Experience in audits or inspections from health authorities • Very good communication and presentation skills • Fluent English required (oral & written); good skills in German and/or French as local site language (oral) desired Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10058702 Aug 11, 2025 Switzerland Summary BDSS QC Bioanalytics is responsible for bioanalytical testing of Biopharmaceuticals for late-phase development projects and commercial products. Applied analytical techniques are mainly cell-based potency assays for bioactivity determination and ELISA /qPCR for the determination of process-related impurities (e.g. host-cell proteins (HCP), residual Protein A, residual DNA). About the Role We are looking for a motivated Senior QC Specialist (Lab Head) to supervise the performance of bioanalytical experiments (i.e. cell-based bioassays, ELISA and qPCR) for quality control (release, stability, and in-process control (IPC) testing) of biotech drug substances (DS) and drug products (DP) in collaboration with members of the own and cross-functional teams in a cGMP environment. Analytical method validation and transfers will be part of the position. Major Accountabilities of the role as Senior QC Specialist (Lab Head) include: Supervision of routine QC testing activities, including line unit approval of analytical records and raw data, investigations of deviations, OOE/OOS, and analytical changes Full compliance with regulatory and cGMP guidelines within the field of responsibility Support of technical project teams as analytical expert Performance of method validations (full ICH validation) and transfers, author of validation- and transfer protocols / -reports Trending and evaluation of analytical data Method lifecycle management for commercial products including method updates, post-approval changes, or troubleshooting Management and coordination of internal and external customer interfaces (e.g. testing/resource requirements, setup of service level agreements) Support in health authority inspections as subject matter expert (e.g. routine GMP inspections, pre-approval inspections) System owner of laboratory equipment and computerized systems including initial qualification and periodic maintenance/functional testing Requirements: PhD or equivalent education in Biology, Biochemistry, Chemistry, or related discipline Several years of experience in analytics / quality control in a leadership role. Experience with Biopharmaceuticals desirable Thorough knowledge of cGMP requirements Results oriented, team player and able to work with all levels of the organization Strong leadership and problem solving skills. Able to identify issues and develop business-friendly solutions in line with the overall compliance Good knowledge of instrument qualification, quality metrics Experience in audits or inspections from health authorities Very good communication and presentation skills Fluent English required (oral & written); good skills in German and/or French as local site language (oral) desired Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Quality Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary Are you an Analytical Expert who can demonstrate creativity in the field of analytical science and technology and with an interest in analytical lifecycle management.? We are looking for an expert who can support not only our current and but also future analytical control strategies for new chemical entities ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Main responsibilities: Analytical expert supporting launch and lifecycle management of projects in collaboration with the analytical project lead and multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Good understanding of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with internal and external stakeholders (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders, colleagues and third parties) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060112 Aug 19, 2025 Switzerland Summary Are you an Analytical Expert who can demonstrate creativity in the field of analytical science and technology and with an interest in analytical lifecycle management.? We are looking for an expert who can support not only our current and but also future analytical control strategies for new chemical entities ensuring long-term supplies to our patients. We play a meaningful role in the late phase delivery, launch and lifecycle management of small molecule drug substances. About the Role Main responsibilities: Analytical expert supporting launch and lifecycle management of projects in collaboration with the analytical project lead and multiple partners Manage product specifications including the design, development, validation, transfer and performance monitoring of analytical procedures/technologies Good understanding of scientific, regulatory and quality standards Ensure training according to cGMP requirements Maintain excellent planning and collaboration with internal and external stakeholders (e.g. laboratory analysts, production specialists, manufacturing science and technology, quality assurance, regulatory CMC, project leaders, colleagues and third parties) Design and plan analytical experiments. Interpret and report results in preparation for timely delivery of project milestones Support change control, preparation of the regulatory dossier and health authority inspections Support root cause investigations (deviations / OOX) Languages : German English. Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Universal Hierarchy Node Location Switzerland Site Basel (Land) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Quality Job Type Full time Employment Type Temporary (Fixed Term) Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary The Scientific Data & Products (SDP) group in Research Informatics (RX) is driven to maximize the impact and value to BR of software and data. We deliver powerful, functional, beautiful, and integrated software solutions that create a frictionless user experience. Our organization is here to build and apply excellence in product and data management to further Novartis drug discovery. About the Role The Data Management group in Research Informatics (RX) is seeking a visionary and technically skilled Data Architect to lead the design and implementation of enterprise-scale data architectures. This role is pivotal in ensuring that biomedical research data is AI-ready, accessible, and interoperable across scientific domains. The focus is on designing robust data architectures, technical stacks, and APIs that enable seamless data integration, governance, and utilization by AI models and data scientists. Major Responsibilities - Design and evolve enterprise-level data architectures that support scientific data interoperability and AI-readiness. - Define and implement technical stacks and APIs to enable secure, scalable, and performant data access. - Establish formal data architecture processes aligned with research data management policies and FAIR principles. - Collaborate with domain experts to define logical data domains, sub-domains, and critical data elements (CDEs). - Inventory and map physical data repositories to logical domains and facilitate metadata capture at data creation. - Develop conceptual and logical data models and document relationships between data objects. - Ensure alignment with scientific standards (e.g., HELM, CDISC) and enforce metadata governance. - Promote the creation of “born FAIR” data and support the publication of CDEs to foundational platforms (e.g., data lakes, warehouses). - Collaborate with IT, data engineering, and security teams to ensure compliance, automation, and operational integration. - Drive architectural improvements and standardization across scientific data workflows. ​ Essential Requirements: - 10+ years of experience in data architecture, data engineering, or software development. - 5+ years in scientific software or drug discovery environments. - Master’s degree or equivalent experience in a relevant field. - Deep expertise in designing data architectures, APIs, and technical stacks. - Experience with RDF, ontologies, cloud platforms (AWS, Google, Azure), and graph databases. - Strong understanding of laboratory data workflows and scientific data types (biology, chemistry, clinical). - Proven ability to align scientific and IT stakeholders around strategic data initiatives. This role offers a unique opportunity to shape the future of data architecture in biomedical research and to enable transformative AI-driven insights. ​ You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Summary Location: this role can be based in Basel Switzerland or Cambridge MA, / East Hanover NJ USA. If applying in the US, please apply to REQ-10060708. LI - #hybrid The Novartis Strategy & Growth Therapeutic Area Strategy team for Neuroscience (NS) is seeking a new Director. This individual will support the creation and update of a holistic TA strategy for NS, provide early-phase commercial insights to project teams, guide TA-specific internal pipeline development and external licensing / acquisitions opportunities and support integrated enterprise alignment across Biomedical Research, Development, Strategy & Growth, and the US and International Commercial units. About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the Neuroscience TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, Neuroscience and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs. To do this effectively, in-market experience in the US is critical. Analyses reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Successfully ensures accurate and timely delivery of key commercial insights for early phase projects to the program teams. Effectively manage the commercial transition from S&G to the US and International commercial units. Actively seeks input into the TA strategy from other internal experts (e.g. the Therapeutic Areas Leadership team). Successfully completes ad-hoc requests as defined. Delivery of agreed health improvement partnership projects on time and within budget. High quality contributions to other HCS group activities. Feedback from project sponsors and (internal and external) key stakeholders regarding quality of project output and interaction. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable In-depth knowledge of Neuroscience (or track record to acquire required TA expertise effectively and rapidly) Experience with NS or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). At least 5-7 years of Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analyzing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Recent (post 2015) local US in-market experience; local US experience includes working within the US market with the local US customers, US health care systems / systems Experience as an equity analyst covering Pharmaceuticals beneficial. Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10060684 Aug 28, 2025 Switzerland Summary Location: this role can be based in Basel Switzerland or Cambridge MA, / East Hanover NJ USA. If applying in the US, please apply to REQ-10060708. LI - #hybrid The Novartis Strategy & Growth Therapeutic Area Strategy team for Neuroscience is seeking a new Director. This individual will support the creation and update of a holistic TA strategy for RLT, provide early-phase commercial insights to project teams, guide TA-specific internal pipeline development and external licensing / acquisitions opportunities and support integrated enterprise alignment across Biomedical Research, Development, Strategy & Growth, and the US and International Commercial units. About the Role Key Responsibilities: Brings external benchmarking, analysis and insights, and judgement to support the Neuroscience TA Strategy Head in developing a holistic Novartis TA strategy that achieves sustainable growth in short, mid and long-term. Brings both understanding of the pharmaceutical industry, Neuroscience and the core Therapeutic Areas (TA) and Disease area to derive insightful and differentiating competitive advantages over our peers. Provides key commercial insights to the R&D project teams, particularly for early phase programs. To do this effectively, in-market experience in the US is critical. Analyses reports and publications to extract key messages, including building product forecasts. Supports development and delivery of TA-specific strategic external insights to support identification of growth opportunities, emerging competitive challenges and support creation of a third-party view around key strategic levers, and commissions targeted primary research. Successfully ensures accurate and timely delivery of key commercial insights for early phase projects to the program teams. Effectively manage the commercial transition from S&G to the US and International commercial units. Actively seeks input into the TA strategy from other internal experts (e.g. the Therapeutic Areas Leadership team). Successfully completes ad-hoc requests as defined. Delivery of agreed health improvement partnership projects on time and within budget. High quality contributions to other HCS group activities. Feedback from project sponsors and (internal and external) key stakeholders regarding quality of project output and interaction. Essential Requirements: Advanced degree (PhD, MD or other advanced University degree) or equivalent experience in life science/healthcare; MBA or consulting or equivalent experience highly desirable In-depth knowledge of Neuroscience, including multiple tumor types (or track record to acquire required TA expertise effectively and rapidly) Experience with NS or demonstrated ability to learn complex, highly technical areas quickly Highly agile having the capacity to support multiple strategic Disease Areas within a TA and multiple programs internal and external Substantial experience evaluating new product opportunities (through M&A, BD&L and internal research programs). At least 5-7 years of Industry pharma and/or medical devices experience in Research & Development and/or Commercial functions with experience conducting, commissioning, analyzing primary research and developing forecasts Experience of strategy development and asset shaping early in lifecycle (any functional perspective) Recent (post 2015) local US in-market experience; local US experience includes working within the US market with the local US customers, US health care systems / systems Commitment to Diversity & Inclusion: We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve. Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in any order to receive more detailed information about essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Benefits and Rewards : Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Strategy & Growth Business Unit Innovative Medicines Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area BD&L & Strategic Planning Job Type Full time Employment Type Regular Shift Work No Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Summary ~Shift Lead I ~Der Schichtleiter ist dafür verantwortlich, sein Team zu leiten, um die Produktionsvorgänge planmäßig in Übereinstimmung mit den HSE- und GMP-Regeln durchzuführen. ~Prozessspezialist / Anlagenspezialist ~Führen Sie zugewiesene Fertigungsaufgaben und -aktivitäten gemäß dem Produktionsplan aus, um die rechtzeitige Produktion von Produkten in der Qualität und Quantität in Übereinstimmung mit den relevanten GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. ~Dokumentationsspezialist GMP ~Der Dokumentationsspezialist GMP prüft und konsolidiert die Chargenprotokolle nach der Produktion, um sie der Qualitätssicherung gemäß den festgelegten Fristen und in der richtigen Qualität zu liefern. Der Dokumentationsspezialist GMP führt Eingaben durch und prüft Transaktionen/Deklarationen im ERP-System. About the Role Hauptaufgaben: · Vorbereitung, Druck und Zusammenstellung der Herstelldokumentation sowie Übergabe an die Produktionsmitarbeitenden gemäß den Vorgaben des Produktionsplans · Nachverfolgung und Koordination der Aktualisierung von Dokumenten in der Produktion · Prüfung und Zusammenstellung der Batchdokumentation nach der Produktion zur fristgerechten Übergabe an die Qualitätssicherung in der geforderten Qualität · Durchführung und Verifizierung von Einträgen und Transaktionen im ERP-System · Archivierung von Produktionsdokumenten Key Performance Indicators: · Einhaltung des Produktionsplans · Rechtzeitige Bereitstellung der Herstelldokumente · Rechtzeitige Freigabe der Herstellaufträge im SAP Ausbildung & Erfahrung: · Ausbildung im administrativen Bereich · Erfahrungen in einem Produktionsbetrieb sind von Vorteil Fähigkeiten: · Sehr gute Kenntnisse in Office Software · SAP-Kenntnisse · Hohes Maß an Gewissenhaftigkeit und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) · Teamfähigkeit und ausgeprägter Teamgeist · Belastbarkeit und Fähigkeit, unter Druck zu arbeiten · Kenntnisse über GMP, Gute Dokumentationspraxis Sprachkenntnisse: · Englischkenntnisse auf mittlerem Niveau sowie sehr gute Kenntnisse der lokalen Sprache am Standort Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job ID REQ-10061459 Sep 11, 2025 Switzerland Summary ~Shift Lead I ~Der Schichtleiter ist dafür verantwortlich, sein Team zu leiten, um die Produktionsvorgänge planmäßig in Übereinstimmung mit den HSE- und GMP-Regeln durchzuführen. ~Prozessspezialist / Anlagenspezialist ~Führen Sie zugewiesene Fertigungsaufgaben und -aktivitäten gemäß dem Produktionsplan aus, um die rechtzeitige Produktion von Produkten in der Qualität und Quantität in Übereinstimmung mit den relevanten GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. ~Dokumentationsspezialist GMP ~Der Dokumentationsspezialist GMP prüft und konsolidiert die Chargenprotokolle nach der Produktion, um sie der Qualitätssicherung gemäß den festgelegten Fristen und in der richtigen Qualität zu liefern. Der Dokumentationsspezialist GMP führt Eingaben durch und prüft Transaktionen/Deklarationen im ERP-System. About the Role Hauptaufgaben: · Vorbereitung, Druck und Zusammenstellung der Herstelldokumentation sowie Übergabe an die Produktionsmitarbeitenden gemäß den Vorgaben des Produktionsplans · Nachverfolgung und Koordination der Aktualisierung von Dokumenten in der Produktion · Prüfung und Zusammenstellung der Batchdokumentation nach der Produktion zur fristgerechten Übergabe an die Qualitätssicherung in der geforderten Qualität · Durchführung und Verifizierung von Einträgen und Transaktionen im ERP-System · Archivierung von Produktionsdokumenten Key Performance Indicators: · Einhaltung des Produktionsplans · Rechtzeitige Bereitstellung der Herstelldokumente · Rechtzeitige Freigabe der Herstellaufträge im SAP Ausbildung & Erfahrung: · Ausbildung im administrativen Bereich · Erfahrungen in einem Produktionsbetrieb sind von Vorteil Fähigkeiten: · Sehr gute Kenntnisse in Office Software · SAP-Kenntnisse · Hohes Maß an Gewissenhaftigkeit und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) · Teamfähigkeit und ausgeprägter Teamgeist · Belastbarkeit und Fähigkeit, unter Druck zu arbeiten · Kenntnisse über GMP, Gute Dokumentationspraxis Sprachkenntnisse: · Englischkenntnisse auf mittlerem Niveau sowie sehr gute Kenntnisse der lokalen Sprache am Standort Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network (link is external) Benefits and Rewards: Read our handbook to learn about all the ways we-ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards Division Operations Business Unit Innovative Medicines Location Switzerland Site Muttenz (with Canteen) Company / Legal Entity C049 (FCRS = CH049) Novartis Pharma Schweizerhalle AG Functional Area Technical Operations Job Type Full time Employment Type Befristet (Innendienst) (Befristet) Shift Work No

Summary Ausführung von zugewiesenen Herstellungsaufgaben und -tätigkeiten gemäß dem Produktionsplan, um die rechtzeitige Produktion des Produkts mit entsprechender Qualität und Quantität gemäß der einschlägigen GMP-, Sicherheits- und Umweltrichtlinien zu ermöglichen. About the Role Hauptverantwortlichkeiten · Teilnahme an den Herstellungsprozessen · Rechtzeitige und fehlerfreie Überprüfung der Chargendokumentation (Teil der Produktion) · Ordentliche und rechtzeitige Reinigung, Vorbereitung und Desinfektion der Produktionsanlagen und -räume · Einhaltung und Durchsetzen der Gesundheits-, Sicherheits- und Umweltregeln und -richtlinien (HSE) · Probenahme, Aliquotierung, Verteilung und Durchführung von prozessbegleitenden Kontrollen · Im Störfall sofortige Maßnahmen ergreifen, Auffälligkeiten an die Manager; Experten und operative Qualitätssicherung melden · Ausführung sämtlich zugewiesener Tätigkeiten gemäß den GMP-, Arbeitsschutz- und Umweltrichtlinien · Sicherstellung/Überwachung einer ordnungsgemäßen Funktionstüchtigkeit der Anlagen, um frühzeitige Anzeichen von Anomalien zu erkennen. Im Störfall geeignete Maßnahmen ergreifen · Exzellente Dokumentation der Maßnahmen, gemäß den GMP-Vorschriften · An Wochenenden/Feiertagen arbeiten und planmäßigen Bereitschaftsdienst haben (Schichtsystem). Mindestanforderungen · Abgeschlossene Ausbildung zum Chemie- und Pharmatechnologen oder gleichwertige Erfahrung · Erfahrung (vorzugsweise) in den Bereichen Chemie/Lebensmittel/Arzneimittel/ Biotechnologie/aseptische Herstellung oder Entwicklung · Kenntnisse über Technik und/oder Prozesse/Produkte · Teamplayer mit gutem Teamgeist · Anpassungsfähigkeit, Fähigkeit unter Druck zu arbeiten · Hohes Pflichtbewusstsein und Sorgfalt (Dokumentation, Ordnung und Sauberkeit am Arbeitsplatz) · Konstruktive Arbeitsweise, Flexibilität, lösungsorientiert, Verantwortung für die eigene Arbeit, tiefes Verständnis der Qualität · Selbstmotivation und Lernfähigkeit · Feinmotorische Fähigkeiten (Umgang mit Analysegeräten, Mikroskopie, Aliquotierung) · Gutes GMP-Verständnis · Gute Kenntnisse in MS Office und Prozessleitsystemen · Grundlegendes technisches Verständnis/der Automatisierung Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network(link is external) Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards